JPH0448494B2 - - Google Patents

Info

Publication number
JPH0448494B2
JPH0448494B2 JP59073122A JP7312284A JPH0448494B2 JP H0448494 B2 JPH0448494 B2 JP H0448494B2 JP 59073122 A JP59073122 A JP 59073122A JP 7312284 A JP7312284 A JP 7312284A JP H0448494 B2 JPH0448494 B2 JP H0448494B2
Authority
JP
Japan
Prior art keywords
capsule
capsules
membrane
volume
concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP59073122A
Other languages
English (en)
Japanese (ja)
Other versions
JPS59206041A (ja
Inventor
Rimu Furankurin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Biotech Inc
Original Assignee
Damon Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Damon Biotech Inc filed Critical Damon Biotech Inc
Publication of JPS59206041A publication Critical patent/JPS59206041A/ja
Publication of JPH0448494B2 publication Critical patent/JPH0448494B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Cosmetics (AREA)
  • Artificial Filaments (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
JP59073122A 1983-04-15 1984-04-13 持続放出システム Granted JPS59206041A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48547183A 1983-04-15 1983-04-15
US485471 1983-04-15

Publications (2)

Publication Number Publication Date
JPS59206041A JPS59206041A (ja) 1984-11-21
JPH0448494B2 true JPH0448494B2 (show.php) 1992-08-06

Family

ID=23928300

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59073122A Granted JPS59206041A (ja) 1983-04-15 1984-04-13 持続放出システム

Country Status (8)

Country Link
EP (1) EP0126537B1 (show.php)
JP (1) JPS59206041A (show.php)
AT (1) ATE54412T1 (show.php)
AU (1) AU567155B2 (show.php)
CA (1) CA1230054A (show.php)
DE (1) DE3482672D1 (show.php)
DK (1) DK193884A (show.php)
IL (1) IL71462A (show.php)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1307632C (en) * 1984-12-21 1992-09-22 Uwe B. Sleytr Forming membrane structure by applying protein suspension to carrier
US4683092A (en) * 1985-07-03 1987-07-28 Damon Biotech, Inc. Capsule loading technique
US4708834A (en) * 1986-05-01 1987-11-24 Pharmacaps, Inc. Preparation of gelatin-encapsulated controlled release composition
IL84167A (en) * 1986-10-24 1991-04-15 Southern Res Inst Oral delivery of bioactive agents to and through the peyer's patch by use of microencapsulation
US5075109A (en) * 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US6024983A (en) * 1986-10-24 2000-02-15 Southern Research Institute Composition for delivering bioactive agents for immune response and its preparation
FR2619503A1 (fr) * 1987-08-20 1989-02-24 Hutchinson Application de microcapsules a la fabrication d'un dispositif prophylactique en materiau elastomere, comme un preservatif ou analogue, et son procede de fabrication
JPH01229046A (ja) * 1988-03-09 1989-09-12 Kibun Kk ゲルの製法
JPH01229047A (ja) * 1988-03-09 1989-09-12 Kibun Kk ゲルの製造法
US7705215B1 (en) 1990-04-17 2010-04-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US6803499B1 (en) 1989-08-09 2004-10-12 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US5550318A (en) * 1990-04-17 1996-08-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US6946587B1 (en) 1990-01-22 2005-09-20 Dekalb Genetics Corporation Method for preparing fertile transgenic corn plants
US6329574B1 (en) 1990-01-22 2001-12-11 Dekalb Genetics Corporation High lysine fertile transgenic corn plants
US5484956A (en) * 1990-01-22 1996-01-16 Dekalb Genetics Corporation Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin
US6777589B1 (en) 1990-01-22 2004-08-17 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
WO1991010725A1 (en) 1990-01-22 1991-07-25 Dekalb Plant Genetics Fertile transgenic corn plants
US6395966B1 (en) 1990-08-09 2002-05-28 Dekalb Genetics Corp. Fertile transgenic maize plants containing a gene encoding the pat protein
US5780709A (en) * 1993-08-25 1998-07-14 Dekalb Genetics Corporation Transgenic maize with increased mannitol content
US6326527B1 (en) 1993-08-25 2001-12-04 Dekalb Genetics Corporation Method for altering the nutritional content of plant seed
US6118047A (en) * 1993-08-25 2000-09-12 Dekalb Genetic Corporation Anthranilate synthase gene and method of use thereof for conferring tryptophan overproduction
US5514377A (en) * 1994-03-08 1996-05-07 The Regents Of The University Of California In situ dissolution of alginate coatings of biological tissue transplants

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3937668A (en) * 1970-07-15 1976-02-10 Ilse Zolle Method for incorporating substances into protein microspheres
GB1414812A (en) * 1970-10-21 1975-11-19 Alza Corp Device for sustained release of drugs and like active agents
AU466503B2 (en) * 1972-06-05 1975-10-30 Alza Corporation Osmotic dispenser
JPS5451979A (en) * 1977-09-30 1979-04-24 Agency Of Ind Science & Technol Granular body with chemical action that its inside occlude chemicals
US4251387A (en) * 1979-04-17 1981-02-17 Damon Corporation Process for preparing semipermeable microcapsules
US4322311A (en) * 1978-08-04 1982-03-30 Damon Corporation Process for producing controlled porosity microcapsules
JPS591087B2 (ja) * 1978-09-21 1984-01-10 ぺんてる株式会社 無機物質壁マイクロカプセル並びにその製造方法
US4205060A (en) * 1978-12-20 1980-05-27 Pennwalt Corporation Microcapsules containing medicament-polymer salt having a water-insoluble polymer sheath, their production and their use
US4221778A (en) * 1979-01-08 1980-09-09 Pennwalt Corporation Prolonged release pharmaceutical preparations
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
US4349530A (en) * 1980-12-11 1982-09-14 The Ohio State University Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal

Also Published As

Publication number Publication date
DE3482672D1 (de) 1990-08-16
JPS59206041A (ja) 1984-11-21
DK193884A (da) 1984-10-16
EP0126537A3 (en) 1986-05-28
ATE54412T1 (de) 1990-07-15
EP0126537B1 (en) 1990-07-11
DK193884D0 (da) 1984-04-13
CA1230054A (en) 1987-12-08
IL71462A0 (en) 1984-07-31
EP0126537A2 (en) 1984-11-28
IL71462A (en) 1988-03-31
AU2643084A (en) 1984-10-18
AU567155B2 (en) 1987-11-12

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