JPH04308515A - Cosmetic composition - Google Patents

Abstract

PURPOSE:To obtain a cosmetic composition protecting hair, providing hair and skin with wetting properties and an oily feeling, natural luster, etc., containing a mixed amount of a keratin peptide ester prepared by esterifying a keratin peptide derived from a keratin. CONSTITUTION:A cosmetic composition ocntaining 0.1-20wt.% keratin peptide ester, e.g. keratin peptide ethyl ester shown by the formula (R1 is side chain of amino acid constituting keratin peptide obtained by hydrolyzing keratin of wool; (n) is 1-50; R2 is alkyl or hydroxylalkyl) prepared by esterifying the keratin peptide. This composition has improved adsorbability on hair and affinity to skin due to the esterification of keratin and provides hair and skin with proper oily feeling, natural luster and gloss. The composition is readily applied, has excellent touch and is safe.

Description

[Detailed description of the invention]

0001

FIELD OF THE INVENTION The present invention relates to cosmetic compositions containing keratin peptide esters.

0002

[Prior Art] Keratin peptides obtained by acid, alkaline or enzymatic hydrolysis of keratin,
Incorporation of keratin peptide derivatives such as acylated products and quaternary ammonium derivatives into cosmetics is being considered (for example, Japanese Patent Application Laid-Open No. 61-69714).
.

[0003] This is because keratin peptides and their derivatives are
This is because it adsorbs to the hair and has the effect of preventing hair damage and restoring damaged hair, and because it is a natural protein derivative, it is less irritating to the hair and skin and is highly safe. be.

0004

[Problems to be Solved by the Invention] However, for those involved in cosmetics research, there is a need to add more useful properties to keratin peptides as cosmetic formulations without impairing the above-mentioned properties of keratin peptides, or to There is a desire to provide keratin peptides with properties that could not be obtained with the proposed derivatives, to further increase their usefulness as cosmetic formulation agents, and to obtain higher quality cosmetics by incorporating them into cosmetics. be.

[0005]

[Means for Solving the Problems] The present inventors synthesized various derivatives using keratin peptides obtained by acid, alkali or enzymatic hydrolysis of keratin, that is, keratin peptides derived from keratin. As a result of various studies on their characteristics, the following general formula (I)

[0006]

[Case 2]

(In the formula, R1 is a side chain of an amino acid constituting a keratin peptide derived from keratin, and n
is 1-50. R2 is an alkyl group having a straight chain or a side chain having 1 to 24 carbon atoms or a hydroxyalkyl group having a straight chain or a side chain having 2 to 24 carbon atoms)

0
The keratin peptide ester represented by [008] has excellent adsorption properties to the hair, has the effect of adsorbing to the hair, protecting the hair, restoring damaged hair, and giving the hair wetness, oily feel, It imparts natural luster and luster, and also has an affinity for the skin, giving the skin a high level of moisture, a moderate oiliness, and a natural luster and luster. It has the characteristics of being easy to absorb, has an excellent texture, and is highly safe.When blending it into conventional hair cosmetics and skin cosmetics, it is necessary to take advantage of the characteristics of the keratin peptide ester mentioned above. They discovered that high-quality cosmetics could be obtained and completed the present invention.

That is, the keratin peptide ester represented by the above general formula (I) has a keratin peptide portion derived from keratin, and has a chemical structure similar to that of the same keratin, hair and the stratum corneum of the skin. It is adsorbed to the hair by its amino group, carboxyl group, or side chain of various amino acids, has the effect of protecting the hair and restoring damaged hair, and imparts wettability to the hair, and also has the effect of improving the skin. It also has an affinity for skin, is easily blended with the skin, provides moisturizing properties to the skin, and is highly safe.

[0010] Esterification causes the carboxyl group of the keratin peptide to disappear, increasing its basicity, further improving its adsorption to hair and affinity for the skin, and making it soluble in organic solvents such as alcohol. Therefore, the range of cosmetics that can be applied is expanded, and the preparation of cosmetics becomes easier. It also dissolves in water. Moreover,
The alkyl group or hydroxyalkyl group introduced through esterification gives the hair and skin a moderate oily feel, natural luster, and luster. In addition, the effect of imparting wettability to hair and skin is further improved by improving adsorption to hair and affinity to skin by esterification. Since it is derived from keratin, which is a natural protein, it is easily compatible with hair and skin, has an excellent texture, and is also excellent in safety.

[0011] Therefore, when the keratin peptide ester represented by the general formula (I) is blended into hair cosmetics, it adsorbs to the hair, protects the hair, and prevents damage, without impairing the properties of the hair cosmetics. The effect of enhancing the effect of restoring damaged hair and imparting wettability, oily feel, natural luster, luster, etc. to the hair is particularly noticeable. In addition, when the keratin peptide ester represented by the above general formula (I) is blended into skin cosmetics, it is possible to impart moisture to the skin, a moderate oily feel, natural gloss, etc. without impairing the properties of the skin cosmetics. The effects of imparting gloss, being easy to blend into the skin, having an excellent feel, and being safe come to be especially noticeable.

In the above general formula (I), amino acids whose side chains are represented by R1 include alanine, glycine, valine, leucine, isoleucine, proline, phenylalanine, tyrosine, serine, threonine, methionine, arginine, histidine, and lysine. , asparagine, aspartic acid, glutamine, glutamic acid, cystine, tryptophan, etc. An example is shown in Table 1.

However, in the amino acid analysis of proteins, the sample is usually completely hydrolyzed using 6N hydrochloric acid before the amino acid analysis, so the amide bond between asparagine and glutamine is hydrolyzed by the complete hydrolysis. become aspartic acid and glutamic acid, respectively. Tryptophan also decomposes and disappears. Therefore, Table 1
In Table 1, asparagine and glutamine are shown as being added to aspartic acid and glutamic acid, respectively, and tryptophan is not quantified, so it is not shown at all in Table 1.

[0014]

[Table 1]

[0015] As a method for producing keratin peptide ester, a method is usually adopted in which first, keratin peptide is derived from keratin, and then the ester is produced. As a method for inducing keratin peptides from keratin, a method of hydrolyzing keratin with acid, alkali or enzyme is adopted. The average molecular weight of the keratin peptide obtained by appropriately selecting acid, alkali or enzymatic hydrolysis conditions is in the range of 100 to 5000, and when expressed as n in general formula (I), n is in the range of 1 to 50. be able to.

The keratin peptide thus obtained is preferably further purified using methods such as ion exchange resin, dialysis, ultrafiltration, and electrodialysis. Decolorization and deodorization are also performed as necessary.

Next, the keratin peptide is esterified after water is removed by vacuum concentration, spray drying, or the like. Esterification, like the esterification of oils and fats, is carried out by mixing with the alcohol to be esterified, heating and stirring for a certain period of time in the presence of an acid or alkali catalyst, preferably in the presence of an acid catalyst.

As the esterification progresses, the keratin peptide becomes dissolved in the reaction solution, so that the progress of the esterification reaction can be confirmed. After the reaction, add an alkali if an acid catalyst is used, or add an acid to neutralize the reaction solution if an alkali catalyst is used, and remove the precipitated salt by filtration to obtain the obtained keratin peptide ester. is usually dissolved in a lower alcohol such as ethanol.

Keratin as a raw material for obtaining keratin peptides includes animal hair such as wool, hair, feathers, hooves,
It is economically advantageous to use eggshell membranes such as nails, horns, chicken eggs, etc., and wool is particularly preferred. It is preferable that these raw materials be cut or pulverized into appropriate sizes as necessary, or subjected to washing, high-temperature pressure treatment, etc., so as to be easily hydrolyzed.

For acid hydrolysis of keratin, for example, inorganic acids such as hydrochloric acid, sulfuric acid, phosphoric acid, nitric acid, and hydrobromic acid, and organic acids such as acetic acid and formic acid are used. For alkaline hydrolysis of keratin, for example, sodium hydroxide, potassium hydroxide, lithium hydroxide, barium hydroxide, sodium carbonate, lithium carbonate, etc. are used.

[0021] When hydrolyzing keratin with enzymes, for example, acidic proteolytic enzymes such as pepsin, protase A, and protase B, and neutral proteolytic enzymes such as papain, bromelain, thermolysin, trypsin, pronase, and chymotrypsin are used. used. Furthermore, fungi-produced neutral proteolytic enzymes such as subtilisin and staphylococcal protease can also be used. When using enzymes, they can be used in the form of bacterial cells containing these bacterially produced proteases, or in the form of membranes, granules, etc. in which enzymes or bacterial cells containing enzymes are immobilized.

[0022] Regarding acid hydrolysis, alkaline hydrolysis, and enzymatic hydrolysis of keratin, for example, JP-A-61
The details are shown in JP-A-69717 and the like. The average molecular weight of the keratin peptide obtained by these acid, alkali or enzymatic hydrolysis is preferably 100 to 5,000. This is expressed as n in general formula (I)
When expressed as n, it corresponds to n=1 to 50. This is because keratin peptide ester has the best adsorption to hair, affinity for skin, and good feel within this range.

That is, when the average molecular weight of the keratin peptide is less than 100, the adsorption to hair and affinity for the skin based on the keratin peptide decrease, so even if esterified, the adsorption of the keratin peptide ester to hair and the affinity for the skin will decrease. If the affinity for the skin and the feel are not as high as desired, and if the molecular weight of the alkyl group or hydroxyalkyl group introduced by esterification is high, the oil solubility increases and the water solubility decreases, making it difficult to handle. On the other hand, if the average molecular weight of the keratin peptide is greater than 5,000, the effect based on the alkyl group or hydroxyalkyl group in the keratin peptide ester will decrease, and the effect of imparting an oily feel, gloss, luster, etc. will decrease, and the molecular weight This is because if the amount is too large, adsorption to hair, affinity for skin, and good feel will be reduced.

[0024] To esterify the keratin peptide,
The keratin peptide obtained as described above is mixed with an alcohol or alkane polyol to be esterified in a lower alcohol such as methanol, ethanol, n-propyl alcohol, or isopropyl alcohol for 1 to 1
The mixture is refluxed around the boiling point of the lower alcohol as a solvent for about 0 hours. At this time, it is preferable to carry out the process under conditions where the liquid contains almost no water. If too much water is contained, esterification will not proceed sufficiently. Further, in order to promote esterification, it is preferable to add a small amount of an acid such as anhydrous hydrochloric acid or sulfuric acid as a catalyst. Progress of esterification can be confirmed by dissolving the keratin peptide in the reaction solution. That is, keratin peptides do not dissolve in lower alcohols, but by making them into ester derivatives, they become soluble in lower alcohols.

The solution of keratin peptide ester obtained as described above is decolorized with activated carbon, or when an acid such as anhydrous hydrochloric acid or sulfuric acid is used as a catalyst, an alkali such as sodium hydroxide or potassium hydroxide is used. In addition, in order to obtain an appropriate concentration, treatments such as distilling off excess lower alcohols or filtering are performed.

The obtained keratin peptide ester can be dried and used in the form of powder, but it is usually a 10 to 40% solution of lower alcohol (concentration is in weight %, and in the following, the concentration is is also weight%)
It is prepared and used as a cosmetic formulation.

[0027] As the alcohol or alkane polyol for esterifying the keratin peptide, those having 1 to 24 carbon atoms are used. This is because when the number of carbon atoms exceeds 24, it becomes too oily and difficult to handle, and even after esterification with the keratin peptide, its properties remain, resulting in the resulting keratin peptide ester being sticky and not pleasant to the touch. The above-mentioned alcohol or alkane polyol may be linear or may have a side chain. The number of carbon atoms in this alcohol or alkane polyol influences the oily feel it imparts to hair and skin, and generally the larger the carbon number, the greater the oily feel.

Preferred specific examples of the alcohol or alkane polyol used to esterify the above keratin peptide include methanol, ethanol, n-propyl alcohol, isopropyl alcohol,
lauryl alcohol, myristyl alcohol, cetyl alcohol, stearyl alcohol, isostearyl alcohol, 2-hexyl-1-decanol, ethylene glycol, propylene glycol, 1,6-hexanediol, 1,12-dodecanediol, glycerin, etc. Especially ethanol, isopropyl alcohol, lauryl alcohol, cetyl alcohol, 2-
Hexyl-1-decanol and the like are preferred.

Cosmetics containing the keratin peptide ester represented by the general formula (I) include, for example, shampoos, hair rinses, permanent wave first agents, permanent wave second agents, hair creams, aerosol foams, and hair care products. Hair cosmetics such as conditioner, setting lotion, hair color, hair bleach, hair treatment, liquid hair lotion, hair liquid, hair pack, hair tonic, hair blow, lotion, nutritional cream, shaving cream, face lotion, Various creams such as aftershave lotion, cleansing cream, emollient cream, cold cream, moisture cream, emulsion, body shampoo, various soaps,
Make-up supplies, nail polish, sunscreen supplies, etc.
Various cosmetics can be mentioned.

In particular, by solubilizing it in organic solvents through esterification, it can be incorporated into hair liquids containing alcohol and other organic solvents, split-end preventers, setting sprays, nail polish, nail polish removers, hair tonics, hair tonics, aftershave lotions, etc. It can be applied to a wide range of applications, such as being able to be used as

The keratin peptide ester represented by the general formula (I) is incorporated in these cosmetics in an amount of 0.1 to 20%. This is because if the keratin peptide ester represented by the general formula (I) is less than 0.1% in the cosmetic composition, the effect of the keratin peptide ester represented by the general formula (I) cannot be fully exhibited, and the cosmetic composition In the product, keratin peptide ester represented by general formula (I) accounts for 20%.
This is because if the keratin peptide ester is excessively left on the hair or skin, it may cause stickiness or an excessively oily feeling.

[0032] Components that can be added to the above cosmetics in combination with the keratin peptide ester represented by the general formula (I) include anionic surfactants, cationic surfactants, nonionic surfactants, amphoteric surfactants, etc. Various surfactants such as activators, polymers such as cationic polymers, anionic polymers, nonionic polymers, and amphoteric polymers, naturally extracted oils, higher fatty acids, hydrocarbons, fatty acid esters, glycerides, waxes, alkyl alcohols, alkyl Oils such as amides, silicone oils (e.g. dimethylpolysiloxane, methylphenylpolysiloxane, and various other modified silicone oils), animal and vegetable protein hydrolysates such as collagen peptides, keratin peptides, silk peptides, soybean peptides, and their derivatives (however, (excluding keratin peptide esters represented by general formula (I)), humectants, alcohols, thickeners, plant extracts, animal extracts, ultraviolet absorbers, pH adjusters, chelating agents, preservatives, pigments, fragrances, etc. Various cosmetic compounding agents can be mentioned.

[0033]

[Examples] Examples of the present invention will be described below.
In explaining the examples, first, esterification of keratin peptide will be cited as a reference example, and then a cosmetic composition containing the keratin peptide ester obtained in the reference example will be cited and explained as an example.

Reference Example 1 Keratin peptide obtained by acid hydrolysis of wool
(Average molecular weight 300, n (n in general formula (I)) =
3. Acid used: 100 g of dehydrated powder of hydrochloric acid was placed in a 500 ml three-necked flask, and 400 g of ethanol was added and heated to the boiling point of ethanol while stirring, and the ethanol was refluxed using a cooling tube. After blowing anhydrous hydrochloric acid gas into the reaction solution at a rate of 20 ml per minute for 15 minutes, reflux was continued for an additional 3 hours to complete the reaction. The reaction solution was cooled and potassium hydroxide was added little by little to the reaction solution while stirring to neutralize the reaction solution. After decolorizing the reaction solution by adding 20 g of activated carbon and removing the activated carbon, an ethanol solution of keratin peptide ethyl ester with a concentration of 25% was obtained by vacuum concentration and filtration.

Reference Example 2 500 ml of 100 g of dehydrated powder of keratin peptide obtained by alkaline hydrolysis of feathers (average molecular weight 2500, n=25, alkali used: sodium hydroxide)
400 g of ethanol was added thereto, and 2 ml of concentrated sulfuric acid was added dropwise while stirring. Heat to the boiling point of ethanol, reflux the ethanol using a cooling tube,
Refluxing was continued for 3 hours to complete the reaction. The reaction solution was cooled and potassium hydroxide was added little by little to the reaction solution while stirring to neutralize the reaction solution. After adding 20 g of activated carbon to the reaction solution and removing the activated carbon, the concentration was reduced to 2 by vacuum concentration and filtration.
A 5% keratin peptide ethyl ester solution in ethanol was obtained.

Reference Example 3 100 g of dehydrated powder of keratin peptide (average molecular weight 1000, n=10, enzyme used: subtilisin) obtained by enzymatic hydrolysis of wool was placed in a 500 ml three-necked flask, and 400 g of ethanol was added and stirred. While
2 ml of concentrated sulfuric acid was added dropwise. The mixture was heated to the boiling point of ethanol, and the ethanol was refluxed using a condenser, and the reflux was continued for 3 hours to complete the reaction. The reaction solution was cooled and potassium hydroxide was added little by little to the reaction solution while stirring to neutralize the reaction solution. 20 g of activated carbon was added to the reaction solution to decolorize it, the activated carbon was removed, and an ethanol solution of keratin peptide ethyl ester with a concentration of 25% was obtained by vacuum concentration and filtration.

Reference Example 4 Keratin peptide obtained by acid hydrolysis of wool (
Put 100 g of dehydrated powder of average molecular weight 500, n=5, acid used: hydrochloric acid into a 500 ml three-necked flask, add 400 g of ethanol and 20 g of 2-hexyl-1-decanol (carbon number 16), and while stirring, pour the powder into a cooling tube. The mixture was heated to boiling point and refluxed. After blowing anhydrous hydrochloric acid gas into the reaction solution at a rate of 20 ml per minute for 30 minutes, reflux was continued for an additional 3 hours to complete the reaction. The reaction solution was cooled and potassium hydroxide was added little by little to the reaction solution while stirring to neutralize the reaction solution. After adding 20 g of activated carbon to the reaction solution and removing the activated carbon, keratin peptide ethyl ester and keratin peptide 2 with a concentration of 25% were concentrated under reduced pressure and filtered.
- An ethanol solution of the mixture with hexyldecyl ester was obtained.

Reference Example 5 50 g of dehydrated powder of keratin peptide obtained by alkaline hydrolysis of wool (average molecular weight 200, n=2, alkali used: sodium hydroxide) was placed in a 500 ml three-necked flask, and 2-hexyl-1 -decanol 4
00g was added thereto, and while stirring, 2ml of concentrated sulfuric acid was added dropwise. Using a cooling tube, heat to 120℃ to 2-hexyl-
1-decanol was refluxed and refluxed for 3 hours to complete the reaction. The reaction solution was cooled and potassium hydroxide was added little by little to the reaction solution while stirring to neutralize the reaction solution. After removing excess 2-hexyl-1-decanol by vacuum distillation, the reaction product was dissolved in 200 g of ethanol, and 20 g of activated carbon was added to the solution to decolorize it. After removing the activated carbon, ethanol was added. An ethanol solution of keratin peptide 2-hexyldecyl ester with a concentration of 25% was obtained.

Next, a cosmetic composition containing the keratin peptide ester obtained in the above reference example will be shown as an example. In principle, the blended amount of each component in the examples is shown in terms of pure content, but for some components, the pure content concentration is written in parentheses after the component name and the total blended amount (water, etc.) is indicated. Indicates the amount (including all other ingredients such as solvent).

Examples 1 to 3 and Comparative Example 1 (Shampoo) Three types of shampoos (Examples 1 to 3) were prepared by blending the keratin peptide ethyl esters obtained in Reference Examples 1 to 3. The blending composition is shown in Table 2. For comparison, a shampoo having the same composition as in Example 1 was prepared, except that the above-mentioned keratin peptide ethyl ester was not blended, and this was designated as Comparative Example 1. Regarding the shampoo of Comparative Example 1,
The composition is shown in Table 2.

[0041]

[Table 2]

Regarding the shampoos of Examples 1 to 3 above 1
A comparative test with the shampoo of Comparative Example 1 was conducted by 0 panelists. The test was conducted by comparing the shampoo of Comparative Example 1 with respect to the moist feeling (moisture) of the hair, the feel of the hair, and the luster of the hair (hair was washed with each shampoo and the hair was compared after washing with water), and the following scoring criteria were used. The total scores were calculated by 10 panelists, and the average values are shown in Table 3.

Scoring Standards Same as Comparative Example 1 0 points Slightly better than Comparative Example 1 1 point Better than Comparative Example 1 2 points Much better than Comparative Example 1 3 points

[0044]

[Table 3]

As shown in Table 3, the shampoos of Examples 1 to 3 had higher scores of 2.5 to 2.7 in terms of moisturizing, texture, and shine, and were higher than the shampoo of Comparative Example 1. It was excellent. This is thought to be due to the fact that the keratin peptide ethyl esters of Reference Examples 1 to 3 that were blended into the shampoo were adsorbed onto the hair, giving the hair wettability, oily feel, natural luster, luster, and the like.

Example 4 (Transparent Shampoo) A transparent shampoo was prepared by blending the mixture of keratin peptide ethyl ester and keratin peptide 2-hexyldecyl ester obtained in Reference Example 4. The composition is as follows.

Keratin peptide ethyl ester and keratin peptide
Mixture with 5.02-hexyldecyl ester (Reference example 4)
Sodium lauryl ether sulfate
7.5 Lauryl sulfate triethanolamine
6.0 coconut oil fatty acid diethanolamide
6.0 Polyoxyethylene higher alkyl ether
0.8 collagen peptide coconut oil fatty acid condensate potassium salt
1.5 [Promois ECP, trade name, manufactured by Seiwa Kasei Co., Ltd.] Polyoxyethylene cetyl ether
0.5 glycerin

3.0EDTA

0.1
Methylparaben

0.2 Propylparaben

0.02 purified water

A total of 100

[0048] The shampoo of Example 4 has a better effect on hair than the shampoo of the same composition as Example 4, except that it did not contain the mixture of keratin peptide ethyl ester and keratin peptide 2-hexyldecyl ester of Reference Example 4. It was able to give a moist feeling (moisture) to the hair, as well as impart a good texture and shine to the hair.

Examples 5 to 6 (Shampoo) A shampoo was prepared by blending the keratin peptide 2-hexyldecyl ester obtained in Reference Example 5. The composition is as follows.

[0050]

Example 5 Example 6 Keratin peptide 2-hexyldecyl ester 3.0
4.0 (Reference Example 5) Soybean peptide [Promois WS, product name, Co., Ltd.
0.5 1.0 Seiwa Kasei] Ammonium lauryl sulfate
30.0 10
．． 0 Sodium lauryl ether sulfate
─
30.0 Coconut oil fatty acid diethanolamide
4.5
5.0 Undecyl-N-hydroxyethyl N-carbo 2.5 2.5
oxymethylimidazolinium betaine isopropyl isostearate
0.5 0
．． 5-cationized cellulose
─
0.3 propylene glycol

─ 1.0 Preservative [Ceycept, trade name, manufactured by Seiwa Kasei Co., Ltd.] 0
．． 5 0.5 fragrance

appropriate amount appropriate
quantity purified water
Both have a total of 100

The shampoos of Examples 5 and 6 were the same as those of Examples 5 and 6 except that the keratin peptide 2-hexyldecyl ester of Reference Example 5 was not blended.
Compared to shampoos with the same composition, this product was able to provide suitable moisture to the hair, as well as give the hair a good texture and shine.

Examples 7 to 8 (Shampoo) A shampoo was prepared by blending the keratin peptide ethyl ester obtained in Reference Example 1. The composition is as follows.

[0053]

Example 7 Example 8 Keratin peptide ethyl ester (Reference example 1) 5
．． 0 5.0 Collagen peptide coconut oil fatty acid condensate sodium 5.0
7.0m salt [Promois ECS, product name, Co., Ltd.
Made by Seiwa Kasei] Collagen peptide isostearic acid condensate 2-2.0 2.
0 amino-2-methyl-1,3-propanediol salt [
Promois E-118D, trade name, manufactured by Seiwa Kasei Co., Ltd.] Sodium lauryl ether sulfate
10.2 9.5
Lauric acid diethanolamide
4.0 4
．． 0 stearyltrimethylammonium chloride
─ 0
．． 3 lauryldimethylaminoacetic acid betaine
2.1 2.
1 polyethyleneimine
0.1
0.1 ethylene glycol monosterate
1.5
─Ethylene glycol distearate
─
1.5EDTA

0.1 0.1 malic acid
0.1
0.1 fragrance

Appropriate amount Appropriate amount Purified water
Both have a total of 100

[0054] The shampoos of Examples 7 and 8 above gave more suitable moisture to the hair than the shampoos of the same composition as Examples 7 and 8, except that the keratin peptide ethyl ester of Reference Example 1 was not blended. In addition, it was possible to impart good texture and shine to the hair.

Example 9 (Shampoo) A shampoo was prepared by blending the keratin peptide ethyl ester obtained in Reference Example 2. The composition is as follows.

Keratin peptide ethyl ester (Reference example 2)
2.5α-
Sodium olefin sulfonate
12.0 Coconut oil fatty acid diethanolamide

4.5 Collagen peptide coconut oil fatty acid condensate potassium
2.
Omu salt (Promois ECP, mentioned above) Cationized cellulose

0.4 Preservative (Ceycept, supra)

0.5 citric acid (pH approximately 7)
0.07 fragrance


Appropriate amount of purified water

A total of 100

The shampoo of Example 9 is the same as that of Reference Example 2.
Compared to the shampoo having the same composition as in Example 9, except that the keratin peptide ethyl ester was not blended, the shampoo was able to provide suitable moisture to the hair, and was able to impart good texture and shine to the hair.

Example 10 (Anti-dandruff shampoo) An anti-dandruff shampoo was prepared by blending the keratin peptide ethyl ester obtained in Reference Example 3. The composition is as follows.

Keratin peptide ethyl ester (Reference example 3)
2.5 Collagen peptide coconut oil fatty acid condensate potassium
3.5 salt (Promois ECP, mentioned above) Coconut oil fatty acid diethanolamide

5.0 Coconut oil fatty acid methyl taurine sodium

10.0 Coconut oil fatty acid ethyl ester sodium sulfonate 2.0
Polyethylene glycol (molecular weight 4 million)
0.01 propylene glycol

10.0EDTA

0.2 triethanolamine

4.0 zinc parathion

1.0 Methylparaben


0.2 dye

Appropriate amount of fragrance


Appropriate amount of purified water

A total of 100

[0060] The anti-dandruff shampoo of Example 10 provides suitable moisture to the hair and improves hair retention compared to the shampoo having the same composition as Example 10 except that the keratin peptide ethyl ester of Reference Example 3 was not blended. It was possible to impart good texture and gloss to the product.

Example 11 (Anti-dandruff shampoo) An anti-dandruff shampoo was prepared by blending the keratin peptide ethyl ester obtained in Reference Example 1. The composition is as follows.

Keratin peptide ethyl ester (Reference example 1)
2.0 coconut oil fatty acid diethanolamide
5
．． 0 Sodium lauryl sulfate

8.0 Polyoxyethylene tridecyl ether sodium acetate
2.0 Thorium Collagen Peptide Undecylenic Acid Condensate Tri
1.5 ethanolamine salt [Promois EUT, trade name, manufactured by Seiwa Kasei Co., Ltd.] EDTA

0.2 Piroctone Olamine

0.2
fragrance

Appropriate amount of purified water

Total 1
Set to 00

[0063] The anti-dandruff shampoo of Example 11 provides suitable moisture to the hair and improves hair retention as compared to the shampoo having the same composition as Example 11 except that the keratin peptide ethyl ester of Reference Example 1 was not blended. It was possible to impart good texture and gloss to the product.

Example 12 (Body Shampoo) Reference Example 2
A body shampoo was prepared by blending the keratin peptide ethyl ester obtained in . The composition is as follows.

Keratin peptide ethyl ester (Reference example 2)
5.0 Collagen Peptide Coconut Oil Fatty Acid Condensate Potassium
3.0m salt (Promois ECP, mentioned above) Coconut oil potash soap

25.0 Lauric acid

2.0
Coconut oil fatty acid diethanolamide

9.0 Potassium hydroxide

0.5 triethanolamine
4.0
Preservative (Ceycept, supra)

0.5EDTA

0.1 fragrance


Appropriate amount of purified water

A total of 100

[0066] The body shampoo of Example 12 above,
A body shampoo with the same composition as Example 12 except that the keratin peptide ethyl ester of Reference Example 2 was not blended (
Using Comparative Example 2), 10 panelists evaluated foaming,
We investigated which one was better in terms of fineness of foam, cleaning power, and moisturizing and gloss of the skin after washing. The results are shown in Table 4.

[0067]

[Table 4]

As shown in Table 4, the body shampoo of Example 12 containing the keratin peptide ethyl ester of Reference Example 2 was compared with the body shampoo of Comparative Example 2 which did not contain the keratin peptide ethyl ester of Reference Example 2. As a result, the foaming, fineness of the foam, and cleaning power were only slightly superior, but the moisturization and shine of the skin after washing were clearly superior. This is because the keratin peptide ethyl ester of Reference Example 2, which is blended into the body shampoo, has excellent affinity for the skin, and by adsorbing to the skin, it gives the skin moisture, moderate oiliness, natural luster, and luster. This is thought to be due to the results of the assignment.

Example 13 (Hair Rinse) A hair rinse was prepared by blending the mixture of keratin peptide ethyl ester and keratin peptide 2-hexyldecyl ester obtained in Reference Example 4. The composition is as follows.

Keratin peptide ethyl ester and keratin peptide
Mixture with 2.52-hexyldecyl ester (Reference example 4) Stearyl alcohol

2.0 Palmityltrimethylammonium chloride

1.2 Distearyldimethylammonium chloride

2.3 Collagen peptide isostearic acid condensate 2-ami 0
．． 7-2-Methyl-1,3-propanediol salt (Promois E-118D, supra) Hexadecyl stearate

2.0 propylene glycol

3.0 preservative (Ceycept, supra)
0.3 malic acid (pH 5.5)

Appropriate amount of fragrance

Appropriate amount of purified water

A total of 100

[0071] The hair rinse of Example 13 and the hair rinse of the same composition as Example 13 except that the mixture of keratin peptide ethyl ester and keratin peptide 2-hexyldecyl ester of Reference Example 4 was not blended (comparative example). 3) (using a commercially available shampoo on the hair after washing and washing with water), 10 panelists evaluated the moistness (moisture), plumpness (volume), and shine of the hair after washing and drying. I investigated whether it is better. The results are shown in Table 5.

[0072]

[Table 5]

As shown in Table 5, the hair rinse of Example 13 containing the mixture of the keratin peptide ethyl ester of Reference Example 4 and the keratin peptide 2-hexyldecyl ester contains the keratin peptide ethyl ester of Reference Example 4 and the keratin peptide 2-hexyldecyl ester. Compared to the hair rinse of Comparative Example 3 which does not contain the mixture with peptide 2-hexyldecyl ester, it gives a moist feeling (moisture) to the hair, and also gives a rich plump feeling (volume feeling) and good gloss. I was able to do that. This is the keratin peptide ethyl ester of Reference Example 4 and the keratin peptide 2-
This is thought to be due to the fact that the mixture with hexyldecyl ester is adsorbed onto the hair, imparting wettability to the hair, and also imparting an appropriate oily feel, natural luster, and luster to the hair.

Examples 14 to 15 (Hair Rinse Cream Type) Hair rinse containing the keratin peptide 2-hexyldecyl ester obtained in Reference Example 5 (Cream Type)
was prepared. The composition is as follows.

[0075]

Example 14 Example 15 Keratin peptide 2-hexyldecyl ester 0.7
0.7 (Reference Example 5) Ethylene glycol distearate
1.5 1.5
isopropyl isostearate
0.5 0
．． 5 cetyl alcohol
2.
5 2.5 Distearyldimethylammonium chloride 1.8
1.8 Coconut oil alkyldimethylammonium derived kola ─
0.3-gen peptide [Promois W-42CAQ
, product name, manufactured by Seiwa Kasei Co., Ltd.] Cationized cellulose
0.3
─Collagen peptide [Promois W-32
R, 1.0
-Product name, manufactured by Seiwa Kasei Co., Ltd.] 1,3-butylene glycol
1.0
1.0 citric acid (pH 5.5)
Appropriate amount
Appropriate amount of purified water

Both have a total of 100

The hair rinses of Examples 14 and 15 above are more suitable for hair than the hair rinses of Examples 14 and 15 with the same composition except that the keratin peptide 2-hexyldecyl ester of Reference Example 5 was not blended. It was able to provide deep moisture, a rich sense of volume, and a good shine.

Example 16 (Hair Treatment) A hair treatment was prepared by blending the keratin peptide ethyl ester obtained in Reference Example 1. The composition is as follows.

Keratin peptide ethyl ester (Reference example 1)
4.0 collagen peptide isostearic acid condensate
5.025% hexadecyl isostearate solution collagen peptide (
Average molecular weight 400)
1.0 stearic acid

13
．． 0 cetyl alcohol

2.0 ethylene glycol monostearate
4.0 Methylparaben

0
．． 2 Silicone oil (dimethylpolysiloxane)
0.
2 triethanolamine

1.6 propylene glycol

8.0EDTA


0.1 fragrance

suitable
quantity purified water

A total of 100

Example 1 except that the hair treatment of Example 16 and the keratin peptide ethyl ester of Reference Example 1 were not blended.
Using a hair treatment (comparative example 4) with the same composition as 6 (used on hair after washing with a commercially available shampoo and water), 10 panelists evaluated the moist feeling (moisture) and plumpness of the hair after washing and drying. Feeling (volume feeling)
, we investigated which one is better in terms of gloss. The results are shown in Table 6.

[0080]

[Table 6]

As shown in Table 6, the hair treatment of Example 16 containing the keratin peptide ethyl ester of Reference Example 1 was superior to the hair treatment of Comparative Example 4, which did not contain the keratin peptide ethyl ester of Reference Example 1. It was able to give the hair a moisturizing feeling (moisture), a rich plump feeling (volume feeling), and a good shine. This is due to the fact that the keratin peptide ethyl ester of Reference Example 1, which was blended into the hair treatment, adsorbs to the hair and imparts moisture to the hair, as well as imparting an appropriate oiliness, natural luster, and luster to the hair. Conceivable.

Examples 17-18 (Hair Treatment) Hair treatments were prepared by blending the keratin peptide ethyl ester obtained in Reference Example 2. The composition is as follows.

[0083]
Example 17 Example 18 Keratin peptide ethyl ester (Reference example 2) 5.0 10
．． 0 Keratin Peptide [Promois WK-HP, Commercial
5.0 ─Product name, (
Seiwa Kasei Co., Ltd. Stearyltrimethylammonium chloride
0.3 0.3 ethyl alcohol
5.0 5
．． 01,3-butylene glycol
5.0
5.0 Methylparaben
0.
3 0.3 Propylparaben

0.1 0.1 Collagen peptide isostearic acid condensate tri 1.0
1.0 Ethanolamine salt (Promois E
-118, supra) Phenoxyethanol
0.5
0.5 fragrance

Appropriate amount Appropriate amount Purified water

Both have a total of 100

[0084] The hair treatments of Examples 17 and 18 above provide more suitable moisture to the hair than hair treatments of the same composition as Examples 17 and 18, except that the keratin peptide ethyl ester of Reference Example 2 was not blended. give,
It was also possible to impart a rich sense of volume and good gloss.

Example 19 (hair conditioner)
A hair conditioner was prepared by blending the keratin peptide ethyl ester obtained in Reference Example 3. The composition is as follows.

Keratin peptide ethyl ester (Reference example 3)
12.0 Stearyl alcohol

1.0 cetyl alcohol

1.0Behenyltrimethylammonium chloride
0.7 Distearyldimethylammonium chloride
0.7 glyceryl monoisostearate
1.0 preservative (Ceycept, supra)

0.3 fragrance

Appropriate amount of glycerin

4.0 hydroxyethyl cellulose
0.5 citric acid (pH
6.5)
Appropriate amount of purified water

A total of 100

[0087] Above Example 19
Example 19 except that the hair conditioner of Example 1 and the keratin peptide ethyl ester of Reference Example 3 were not blended.
Using a hair conditioner (Comparative Example 5) with the same composition as (used on hair after washing with a commercially available shampoo or washing with water), 10 panelists evaluated the combability, the moist feeling (moisture) of the hair after drying, We investigated which one is better in terms of plumpness (volume) and shine. The results are shown in Table 7.

[0088]

[Table 7]

As shown in Table 7, the hair conditioner of Example 19 containing the keratin peptide ethyl ester of Reference Example 3 was superior to the hair conditioner of Comparative Example 5, which did not contain the keratin peptide ethyl ester of Reference Example 3. As a result, it was possible to give the hair good combability and a moist feeling (moisture), as well as a rich plump feeling (voluminous feel) and good gloss. This is because the keratin peptide ethyl ester of Reference Example 3, which is blended into the hair conditioner, is adsorbed onto the hair, imparting shine to the hair, making the hair smoother, and giving the hair a moisturizing effect, a moderate oily feel, and a natural texture. This is thought to be due to the addition of a glossy finish.

Example 20 (Permanent wave first agent) A permanent wave first agent was prepared by blending the mixture of keratin peptide ethyl ester and keratin peptide 2-hexyldecyl ester obtained in Reference Example 4. The composition is as follows. Note that the pH of the first permanent wave agent was adjusted to 9.2.

Mixture of keratin peptide ethyl ester and keratin peptide 2 7,5-hexyldecyl ester (Reference example 4) Ammonium thioglycolate (50%)
12.0 Ammonia water (28
%)
3.5 Amodimethicone (SM8702C, trade name, manufactured by Torre)
0.8EDTA


0.1 fragrance

Appropriate amount of cetyltrimethylammonium chloride

0.2 Purified water

A total of 100

Permanent wave first agent of Example 20, keratin peptide ethyl ester and keratin peptide 2 of Reference example 4
A permanent wave first agent (comparative example 6) having the same composition as in Example 20 was used, except that the mixture with hexyldecyl ester was not blended, and 1 g of hair was wrapped around a rod in each first agent. After rinsing with water, the hair bundle was wrapped around a rod and immersed in a second permanent wave agent consisting of an 8% aqueous solution of sodium bromate for 15 minutes at a temperature of 35°C to create a permanent wave. Wave processing was performed.

After washing and drying each hair bundle, 10 panelists evaluated the moistness (moisture) and plumpness of the hair.
It was determined which permanent wave first agent was better in terms of (volume feel), hair gloss, and hair feel. The results are shown in Table 8.

[0094]

[Table 8]

As shown in Table 8, the permanent wave first agent of Example 20 containing the mixture of the keratin peptide ethyl ester of Reference Example 4 and the keratin peptide 2-hexyldecyl ester was Compared to the first permanent wave agent of Comparative Example 6, which does not contain a mixture of ester and keratin peptide 2-hexyldecyl ester, it provides a suitable moisturizing feeling (moisture) to the hair and a rich plump feeling (volume feeling). ), giving good shine and greatly improving the feel of the hair. This is because the mixture of keratin peptide ethyl ester and keratin peptide 2-hexyldecyl ester of Reference Example 4, which was blended into the first permanent wave agent, adsorbs to the hair and prevents hair damage caused by permanent wave treatment. This is thought to be due to the fact that it not only imparts wettability to the hair, but also imparts a moderate oiliness, natural luster, and luster to the hair.

Example 21 (Permanent Wave 2nd
Agent) A second permanent wave agent was prepared by blending the keratin peptide ethyl ester obtained in Reference Example 1. The composition is as follows.

Keratin peptide ethyl ester (Reference example 1)
7.5
sodium bromate

6.0 citric acid

0.01 sodium citrate

0.3 Stearylbenzyldimethylammonium chloride
0.2 Purified water

A total of 100

[0098]
When the second permanent wave agent of Example 21 was used for oxidation after the use of the first permanent wave agent with ordinary ammonium thioglycolate as a reducing agent, the keratin peptide ethyl ester of Reference Example 1 was not blended. Other than that, compared to the second permanent wave agent having the same composition as in Example 21, it was able to impart suitable moisture, volume, gloss, and good texture to the hair.

Example 22 (Hair Cream) A hair cream was prepared by blending the keratin peptide 2-hexyldecyl ester obtained in Reference Example 5. The composition is as follows.

Keratin peptide 2-hexyldecyl ester
5.0 (
Reference example 5) Collagen peptide isostearic acid condensate
0.325
% liquid paraffin solution [Promois E-118 (MO)
, Product name, Seiwa Kasei Co., Ltd. Hexadecyl stearate
7.0 stearic acid

13.0 cetyl alcohol

2.0 ethylene glycol monostearate
4.0 Preservative (Ceycept, supra)

0.3 silicone oil (dimethylpolysiloxane)

0.2 triethanolamine

1.6 propylene glycol

8.0EDT
A

0.1 fragrance


Appropriate amount of purified water

A total of 100

Hair cream of the same composition as Example 22 except that the hair cream of Example 22 and the keratin peptide 2-hexyldecyl ester of Reference Example 5 were not blended (Comparative Example 7)
(Used on hair after washing, rinsing, and drying with a commercially available shampoo), 10 panelists asked which one was better in terms of moisturizing (moisture), shine, and texture of the hair after 3 hours. Examined. The results are shown in Table 9.

[0102]

[Table 9]

As shown in Table 9, Example 2 in which the keratin peptide 2-hexyldecyl ester of Reference Example 5 was blended
Hair cream No. 2 contains Keratin Peptide 2 of Reference Example 5.
-Moisturizing feeling suitable for hair compared to the hair cream of Comparative Example 7 which does not contain hexyldecyl ester (
It was able to provide moisture), give good luster to the hair, and improve the feel of the hair. This is because the keratin peptide 2-hexyldecyl ester of Reference Example 5, which was blended into the hair cream, was adsorbed to the hair, giving it moisture, a moderate oily feel, a natural luster, etc., and making the hair smooth. This is thought to be due to the results.

Example 23 (Nutritional Cream) A nutritional cream was prepared by blending the mixture of keratin peptide ethyl ester and keratin peptide 2-hexyldecyl ester obtained in Reference Example 4. The composition is as follows.

Keratin Peptide Ethyl Ester and Keratin Pep
5.0 chido 2
-Mixture of hexyldecyl ester (Reference example 4) Emulsifier [Ayacol LC-WAX, trade name,
4.5(
Seiwa Kasei Co., Ltd.] Emulsifier [Ayacol GTISS, trade name,
6.0
Manufactured by Seiwa Kasei Co., Ltd.] Octyl isopalmitate

6.0 Isopropylisostearate

3.5 Glyceryl Monoisostearate
2.0 stearic acid


4.5 Silicone oil (polydimethylsiloxane)

0.2 methylparaben

0.2 Propylparaben

0.
1 triethanolamine

0.21,3-butylene glycol

10.0 Glycerin


4.0EDTA

0.1 fragrance


Appropriate amount of purified water

A total of 100

[
[0106] Nutritional cream of Example 23 above and Reference Example 4
A nutritional cream (Comparative Example 8) having the same composition as in Example 23 was used, except that the mixture of keratin peptide ethyl ester and keratin peptide 2-hexyldecyl ester was not blended (used after washing the face with commercially available soap). 1
After 3 hours of use, 0 panelists gave a 5-point rating (from 1 to
(5 points, higher numbers indicate better). The results (average of evaluations by 10 people) are shown in Table 10.

[0107]

[Table 10]

As shown in Table 10, the nutritional cream of Example 23 containing the mixture of the keratin peptide ethyl ester of Reference Example 4 and the keratin peptide 2-hexyldecyl ester contains the keratin peptide ethyl ester of Reference Example 4 and the keratin Compared to the nutritional cream of Comparative Example 8 which did not contain the mixture with peptide 2-hexyldecyl ester, it was easy to adapt to the skin and had an excellent effect of imparting suitable moisture to the skin and softening the skin. This is because the mixture of keratin peptide ethyl ester and keratin peptide 2-hexyl decyl ester of Reference Example 4, which is blended into the nutritional cream, has excellent affinity with the skin, and by adsorbing to the skin, it provides moisturizing and moderate moisture to the skin. This is thought to be due to the fact that it imparts an oily feel and softens the skin.

Example 24 (Face lotion) A face lotion was prepared by blending the keratin peptide ethyl ester obtained in Reference Example 2. The composition is as follows.

Keratin peptide ethyl ester (Reference example 2)
10.0 carboxyvinyl polymer

0.11,3-butylene glycol

5.0 Collagen peptide isostearic acid condensate
0.3 ethanolamine salt [Promois E
-118T, product name, manufactured by Seiwa Kasei Co., Ltd.] Aloe extract

1.0 preservative (Ceycept, supra)
0.3 Sodium hydroxide (to pH 6)
Appropriate amount of purified water

A total of 100

[0111] A face lotion (Comparative Example 9) having the same composition as that of Example 24 was used, except that the face lotion of Example 24 and the keratin peptide ethyl ester of Reference Example 2 were not blended (after washing the face with commercially available soap). 1 hour after use, 10 panelists evaluated the ease of adhesion to the skin, skin moisture,
Flexibility was evaluated on a five-point scale (1 to 5 points, the higher the number, the better). The results (average of evaluations by 10 people) are shown in Table 11.

[0112]

[Table 11]

[0113] As shown in Table 11, the face lotion of Example 24 containing the keratin peptide ethyl ester of Reference Example 2 was superior to the face lotion of Comparative Example 9 which did not contain the keratin peptide ethyl ester of Reference Example 2. It was easy to blend into the skin, provided suitable moisture to the skin, and had excellent skin softening effects. This is due to the fact that the keratin peptide ethyl ester of Reference Example 2, which was blended into the face lotion, has excellent affinity with the skin and imparts moisture and a moderate oily feel to the skin, making it soft. Conceivable.

Example 25 (Shaving cream, aerosol foam type) A shaving cream (aerosol foam type) was prepared by blending the keratin peptide ethyl ester obtained in Reference Example 1. The composition is as follows.

Keratin peptide ethyl ester (Reference example 1)
10.0 Collagen peptide myristic acid condensate tri
6.0 Ethanolamine Salt [Promois EMT, trade name, Co., Ltd.
Made by Seiwa Kasei Cetyl Alcohol

0.5 isopropyl isostearate
1.0 polyether modified silicone
1.0 (SH
3772C, trade name, manufactured by Torre) Butylparaben


0.1 collagen peptide coconut oil fatty acid condensate potash
3
．． 5um salt (Promois ECP, mentioned above) Glycerin

5.0 fragrance


Appropriate amount of purified water

A total of 100

[0116] The above base

90.0 dimethyl ether

10.0

0
117] The shaving cream of Example 25 gives better moisture and shine to the skin and is milder than the shaving cream of the same composition as Example 25 except that the keratin peptide ethyl ester of Reference Example 1 was not blended. It was possible to give a refreshing feel.

Example 26 (Aftershave lotion) The keratin peptide ethyl ester obtained in Reference Example 2 was blended to prepare an aftershave lotion. The composition is as follows.

Keratin peptide ethyl ester (Reference example 2)
8.0
Collagen peptide isostearic acid condensate
0.72
-Amino-2-methyl-1,3-propanediol salt (
Promois E-118D, supra) Emulsifier [Ayacol A-100, trade name,
2.0
Made by Seiwa Kasei Co., Ltd. Menthol

0.1 fragrance


Appropriate amount of ethanol

63.0 Purified water


A total of 100

[0120] The above base

8.0 Propane/Butane: 50
/50
92.0

[0121] The aftershave lotion of Example 26 has the same composition as Example 26, except that the keratin peptide ethyl ester of Reference Example 2 was not blended, and the aftershave lotion of Example 26 provides moisture and shine suitable for the skin. It was possible to impart a mild and refreshing feel to the skin.

Example 27 (Liquid hair styling product) The keratin peptide ethyl ester obtained in Reference Example 3 was blended to prepare a liquid hair styling product. The composition is as follows.

Keratin peptide ethyl ester (Reference example 3)
8.0
Diisobutyl adipate

0.3 collagen peptide isostearic acid condensate 2-
0.6amino-2-methyl-1,3-propanediol salt (Promois E-118D, supra) Polyoxypropylene monobutyl ether
21.0 ethanol

50.0 Biosol

0.1 propylene glycol

3.0 fragrance

Appropriate amount of purified water

A total of 100

[0124] The liquid hair preparation of Example 27 has more moisture and shine suitable for hair than the liquid hair preparation of the same composition as Example 27 except that the keratin peptide ethyl ester of Reference Example 3 was not blended. I was able to grant it.

Example 28 (Hair tonic) Reference example 5
A hair tonic was prepared by blending the keratin peptide 2-hexyldecyl ester obtained in . The composition is as follows.

Keratin peptide 2-hexyldecyl ester (Reference example 5) 5.0 Ethanol


60.0 diisobutyl adipate

0.5 Togarashi tincture

0.4
L-menthol

0.4 Calcium pantothenate

0.4 vitamin B
6

0.2L-cystine

0.005 Hinokitiol

0.1EDTA

0.0 biosol

0.1 fragrance


Appropriate amount of purified water

A total of 100

[0127] The hair tonic of Example 28 has a natural luster and is more suitable for hair than the hair tonic of the same composition as that of Example 28 except that the keratin peptide 2-hexyldecyl ester of Reference Example 5 was not blended. It was able to provide intense moisture and maintain its effect for a long time.

Example 29 (Hair tonic) Reference example 1
A hair tonic was prepared by blending the keratin peptide ethyl ester obtained in . The composition is as follows.

Keratin peptide ethyl ester (Reference example 1)
4.0
Diisobutyl adipate

0.3 collagen peptide isostearic acid condensate 2-
0.6amino-2-methyl-1,3-propanediol salt (Promois E-118D, supra) Biosol

0.1 salicylic acid

0.2L
−Menthol

0.2 carpronium chloride

0.5 ethanol

66.0 fragrance

suitable
quantity purified water

A total of 100

[0130] The hair tonic of Example 29 has the same composition as Example 29, except that it does not contain the keratin peptide ethyl ester of Reference Example 1, and provides natural luster and suitable moisture to the hair. The effect was able to be maintained for a long time.

Example 30 (Hair blow, spray type) A hair blow (spray type) was prepared by blending the mixture of keratin peptide ethyl ester and keratin peptide 2-hexyldecyl ester obtained in Reference Example 4. The composition is as follows.

Keratin peptide ethyl ester and keratin peptide
Mixture with 2.52-hexyldecyl ester (Reference Example 4) Collagen peptide isostearic acid condensate 2-
0.5amino-2-methyl-1,3-propanediol salt (Promois E-
118D, supra) Cetyltrimethylammonium chloride
1.0 polyvinylpyrrolidone

1.0 ethanol

90.0 fragrance

suitable
quantity purified water

A total of 100

[0133] The above base

85.0 dimethyl ether

10.0 carbon dioxide

5.0

[0134] Above Example 3
The hair blow of No. 0 has a natural effect on the hair compared to the hair blow of the same composition as in Example 29 except that the combination of keratin peptide ethyl ester and keratin peptide 2-hexyldecyl ester of Reference Example 4 was not blended. It gives shine and keeps hair moisturized, so the blowout effect can be maintained for a longer period of time.

Example 31 (Nail polish) A nail polish was prepared by blending the keratin peptide ethyl ester obtained in Reference Example 1. The composition is as follows.

Keratin peptide ethyl ester (Reference example 1)
5.0 Pigment and Solvent Mixture (Marmaid TX Con
15.5k, trade name, manufactured by Marl) Pigment

Appropriate amount of lacquer No.
92 (manufactured by Marl Corporation)
A total of 100

[0137] The nail polish of Example 31 had better luster and luster than the nail polish of the same composition as Example 31 except that it did not contain the keratin peptide ethyl ester of Reference Example 1, and
It stayed that way for a long time.

Example 32 (Nail enamel remover)
A nail enamel remover was prepared by blending the mixture of keratin peptide ethyl ester and keratin peptide 2-hexyldecyl ester obtained in Reference Example 4. The composition is as follows.

Keratin peptide ethyl ester and keratin peptide
4. Mixture with 2-hexyldecyl ester (Reference Example 4) Ethyl acetate


25.0 Propylene glycol

10.0 Isopropyl alcohol
20.0 acetone

27.0 Polyoxyethylene (16) Lanolin Ether
2.0 polyacrylic acid (Carbopol 934
, product name, good 1
．． (Manufactured by 5Rich) Polyoxyethylene (20) Beef tallow alkylamine
1.5 Purified water

A total of 100

The nail enamel remover of Example 32 was the same as Example 32 except that the mixture of keratin peptide ethyl ester and keratin peptide 2-hexyldecyl ester of Reference Example 4 was not blended.
Compared to a nail enamel remover with the same composition, damage to the nails after removal was reduced, and the gloss and luster of the nails were maintained.

Example 33 (lipstick, cream) Reference example 5
A lipstick (cream) was prepared by blending the keratin peptide 2-hexyldecyl ester obtained in . The composition is as follows.

Keratin peptide 2-hexyldecyl ester (Reference example 5) 7.5 Beeswax

1
2.0 Synthetic Whale Wax

8.0 Vaseline


24.0 Liquid paraffin

18.0 borax


0.8 methylparaben

0.1 pigment


Appropriate amount of purified water

A total of 100

[0143] The lipstick of Example 33 had better adhesion and superior luster and luster than the lipstick of the same composition as Example 33 except that it did not contain the keratin peptide 2-hexyldecyl ester of Reference Example 5. , and it was maintained for a long time.

[0144]

Effects of the Invention As explained above, in the present invention, by blending the keratin peptide ester represented by the general formula (I) into cosmetics, each cosmetic can
The keratin peptide ester represented by the general formula (I) has excellent adsorption to hair, protective effect on hair, excellent affinity for skin, wettability to hair and skin, moderate oiliness, natural luster, and luster. We were able to improve the quality of each cosmetic product by exerting the effect of imparting properties such as

Claims (1)

[Claims] Claim 1: General formula (I) [Formula 1] (wherein, R1 is a side chain of an amino acid constituting a keratin peptide derived from keratin, and n is 1 to 50. R2 is a carbon number of 1 - 0.1 to 20% by weight of keratin peptide ester represented by an alkyl group having a straight chain or side chain of ~24 or a hydroxyalkyl group having a straight chain or side chain having 2 to 24 carbon atoms. Cosmetic compositions characterized by: