JPH04305229A - Hollow yarn type mass-transfer device - Google Patents
Hollow yarn type mass-transfer deviceInfo
- Publication number
- JPH04305229A JPH04305229A JP9485891A JP9485891A JPH04305229A JP H04305229 A JPH04305229 A JP H04305229A JP 9485891 A JP9485891 A JP 9485891A JP 9485891 A JP9485891 A JP 9485891A JP H04305229 A JPH04305229 A JP H04305229A
- Authority
- JP
- Japan
- Prior art keywords
- header
- hollow fiber
- port
- casing
- transfer device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000012546 transfer Methods 0.000 title claims abstract description 11
- 239000000463 material Substances 0.000 claims abstract description 15
- 239000012510 hollow fiber Substances 0.000 claims description 45
- 238000005192 partition Methods 0.000 claims description 13
- 230000004087 circulation Effects 0.000 claims description 11
- 230000015572 biosynthetic process Effects 0.000 abstract description 4
- 239000002244 precipitate Substances 0.000 abstract description 3
- 239000008280 blood Substances 0.000 description 23
- 210000004369 blood Anatomy 0.000 description 23
- 239000000126 substance Substances 0.000 description 19
- 210000003734 kidney Anatomy 0.000 description 10
- 230000017531 blood circulation Effects 0.000 description 8
- 230000002093 peripheral effect Effects 0.000 description 6
- 208000007536 Thrombosis Diseases 0.000 description 5
- 238000012545 processing Methods 0.000 description 5
- 241000283690 Bos taurus Species 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 238000000926 separation method Methods 0.000 description 4
- 238000009825 accumulation Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 239000004743 Polypropylene Substances 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229920003002 synthetic resin Polymers 0.000 description 2
- 239000000057 synthetic resin Substances 0.000 description 2
- 238000004026 adhesive bonding Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000005374 membrane filtration Methods 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920000379 polypropylene carbonate Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 238000004382 potting Methods 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000004627 regenerated cellulose Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 238000001223 reverse osmosis Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/21—Specific headers, end caps
Abstract
Description
【０００１】0001
【産業上の利用分野】本発明は、中空糸を利用した透析
、限外濾過、膜濾過、逆浸透、気−気分離、気−液分離
、液−液分離、固−液分離等に用いられる中空糸型物質
移動装置に関する。[Industrial Application Field] The present invention is applicable to dialysis, ultrafiltration, membrane filtration, reverse osmosis, gas-gas separation, gas-liquid separation, liquid-liquid separation, solid-liquid separation, etc. using hollow fibers. The present invention relates to a hollow fiber type mass transfer device.
【０００２】0002
【従来の技術】中空糸型物質移動装置は、例えば特公昭
６３−５２５２２号公報に記載の如く、ケーシング内に
多数の中空糸が装填され、該中空糸束の端部が該ケーシ
ングの端部に充填固化される合成高分子材料の隔壁部材
により支持されて各中空糸の開口部が該隔壁部材の外端
面に開口される。2. Description of the Related Art A hollow fiber type mass transfer device, as described in Japanese Patent Publication No. 63-52522, has a casing loaded with a large number of hollow fibers, and the ends of the hollow fiber bundle are connected to the ends of the casing. The hollow fibers are supported by a partition wall member made of a synthetic polymer material that is filled and solidified, and the openings of each hollow fiber are opened at the outer end surface of the partition wall member.
【０００３】そして、各中空糸の開口部全体を包囲する
漏斗状ヘッダーの大径被着口部が該ケーシングの端部に
接続され、該ヘッダーの小径接続口部には第１物質（例
えば血液）循環回路が接続され、該ケーシングに設けた
接続口部には、該中空糸束の周囲の空間に連通する第２
物質（例えば透析液）循環回路が接続される。[0003]The large-diameter attachment port of a funnel-shaped header that surrounds the entire opening of each hollow fiber is connected to the end of the casing, and the small-diameter connection port of the header is connected to a first substance (for example, blood). ) A circulation circuit is connected to the connection port provided in the casing, and a second connection port is connected to the connection port provided in the casing.
A substance (eg dialysate) circulation circuit is connected.
【０００４】0004
【発明が解決しようとする課題】然しながら、従来技術
では、第１物質が流入するヘッダー内で第１物質の偏流
及び滞溜を生じ、その滞溜部に沈殿物又は堆積物の生成
を見ることがある。特に第１物質が血液の場合には血栓
が生成される。[Problems to be Solved by the Invention] However, in the prior art, the first substance is caused to drift and stagnate in the header into which the first substance flows, and precipitation or deposits are formed in the stagnation part. There is. In particular, when the first substance is blood, a thrombus is generated.
【０００５】尚、上述のヘッダー内における第１物質の
偏流及び滞溜の発生は、ヘッダーの小径接続口部に接続
される第１物質循環回路がヘッダー軸心に対して曲がり
をなす等において顕著である。Incidentally, the above-mentioned occurrence of drifting and accumulation of the first substance in the header becomes noticeable when the first substance circulation circuit connected to the small-diameter connection port of the header is bent with respect to the axis of the header. It is.
【０００６】本発明は、中空糸型物質移動装置において
、第１物質が流入するヘッダー内で第１物質の偏流及び
滞溜をなくし、沈殿物又は堆積物の生成を見ることなく
、良好な物質処理性能を確保することを目的とする。[0006] In a hollow fiber type mass transfer device, the present invention eliminates uneven flow and stagnation of the first substance in the header into which the first substance flows, and produces a good quality of the substance without the formation of precipitates or deposits. The purpose is to ensure processing performance.
【０００７】[0007]
【課題を解決するための手段】請求項１に記載の本発明
は、ケーシング内に多数の中空糸が装填され、該中空糸
束の端部が該ケーシングの端部の隔壁部材により支持さ
れて各中空糸の開口部が該隔壁部材の外端面に開口され
、各中空糸の開口部全体を包囲する少なくとも１つの漏
斗状ヘッダーの大径被着口部が該ケーシングの端部に接
続され、該ヘッダーの小径接続口部には第１物質循環回
路が接続され、該ケーシングに設けた接続口部には該中
空糸束の周囲の空間に連通する少なくとも１つの第２物
質循環回路が接続されて構成される中空糸型物質移動装
置において、該ヘッダーの内面が、該被着口部側の略テ
ーパ部と、該接続口部側の略ストレート部とを、アール
部にて連続化したものであり、該ヘッダーの被着口部内
径をＤとし、該ヘッダーの該被着口部から該接続口部ま
での高さをＨとし、該略テーパ部の勾配をθとし、該略
ストレート部の頂角をφとするとき、０．８≦Ｈ／Ｄ≦
１．３ 、θ≦７ 度、１８度≦φ≦２２度であるよう
にしたものである。Means for Solving the Problems The present invention as set forth in claim 1 is characterized in that a large number of hollow fibers are loaded in a casing, and the ends of the hollow fiber bundle are supported by partition members at the ends of the casing. The opening of each hollow fiber is opened at the outer end surface of the partition member, and the large-diameter adhesion portion of at least one funnel-shaped header that surrounds the entire opening of each hollow fiber is connected to the end of the casing; A first material circulation circuit is connected to the small-diameter connection port of the header, and at least one second material circulation circuit that communicates with the space around the hollow fiber bundle is connected to the connection port provided in the casing. In the hollow fiber type mass transfer device, the inner surface of the header has a substantially tapered part on the side of the adhering port and a substantially straight part on the side of the connecting port, which are made continuous at a rounded part. , the inner diameter of the header opening is D, the height from the header opening to the connection port is H, the slope of the approximately tapered portion is θ, and the approximately straight portion is When the apex angle of is φ, 0.8≦H/D≦
1.3, θ≦7 degrees, and 18 degrees≦φ≦22 degrees.
【０００８】請求項２に記載の本発明によれば、請求項
１に記載の本発明において更に、前記アール部が、前記
略テーパ部と前記略ストレート部とを最大曲率半径にて
連続化するようにしたものである。According to the present invention as set forth in claim 2, in the present invention as set forth in claim 1, the rounded portion further connects the substantially tapered portion and the substantially straight portion with a maximum radius of curvature. This is how it was done.
【０００９】[0009]
【作用】請求項１に記載の本発明によれば、下記■〜■
の作用がある。[Operation] According to the present invention as set forth in claim 1, the following ■ to ■
There is an effect.
【００１０】■０．８ ≦Ｈ／Ｄ≦１．３ において、
第１物質循環回路からヘッダー内に導入される第１物質
の流線をヘッダー軸心方向に規制する、ヘッダー高さ方
向経路（特に略ストレート部の経路）長さが、適度とな
る（０．９ ≦Ｈ／Ｄ≦１．１ であれば、より適度と
なる）。このため、第１物質はヘッダー内にてヘッダー
軸心方向に沿う適度なストレート流れとなるように整流
される。■0.8≦H/D≦1.3,
The length of the path in the height direction of the header (particularly the path of the substantially straight portion) that regulates the streamlines of the first material introduced into the header from the first material circulation circuit in the axial direction of the header becomes appropriate (0. If 9≦H/D≦1.1, it becomes more appropriate). For this reason, the first substance is rectified in the header so as to have an appropriate straight flow along the header axial direction.
【００１１】■１８度≦φ≦２２度において、上記■に
より整流される第１物質の流れが、ヘッダー内の略スト
レート部を経るに際し、均一な拡がりを持ちながら、中
空糸の開口部へ進み、該第１物質を中空糸へと導入せし
める。[0011] ■ At 18 degrees ≦ φ ≦ 22 degrees, the flow of the first substance rectified by the above-mentioned (■) advances to the opening of the hollow fiber while spreading uniformly as it passes through the approximately straight part in the header. , the first substance is introduced into the hollow fiber.
【００１２】■θ≦ ７度において、ヘッダー内の周辺
部分である略テーパ部の勾配が浅くなり、第１物質の周
辺部分での線速度を上げ、結果として第１物質の流速を
周辺部分においても低下することなく、該第１物質を中
空糸へと導入せしめる。[0012] When θ≦7 degrees, the slope of the substantially tapered portion, which is the peripheral portion in the header, becomes shallower, increasing the linear velocity of the first material in the peripheral portion, and as a result, the flow velocity of the first material decreases in the peripheral portion. This allows the first substance to be introduced into the hollow fibers without decreasing the quality.
【００１３】■上記■〜■により、第１物質はヘッダー
内に偏流を生ずることなく、結果として、ヘッダー内に
滞溜部を生ずることがなく、特に、第１物質が血液の場
合には血栓の発生をみることがない。よって、良好な物
質処理性能を確保できる。[0013] As a result of the above-described steps (■) to (■), the first substance does not cause a biased flow in the header, and as a result, no stagnation is generated in the header, and especially when the first substance is blood, blood clots are prevented. I have never seen this occur. Therefore, good material processing performance can be ensured.
【００１４】請求項２に記載の本発明によれば、下記■
の作用がある。According to the present invention as set forth in claim 2, the following
There is an effect.
【００１５】■上記■の略ストレート部と、上記■の略
テーパ部とを、最大曲率半径のアール部にて連続化する
ことにより、ヘッダー内に第１物質の偏流と滞溜のない
、より均一な流れを形成できる。[0015] By making the substantially straight part of the above (■) and the substantially tapered part of the above (2) continuous at the rounded part with the maximum radius of curvature, it is possible to prevent the first substance from drifting and accumulating in the header. A uniform flow can be formed.
【００１６】[0016]
【実施例】図１は本発明に係るヘッダー形状の一例を示
す断面図、図２は本発明に係るヘッダー形状を選定する
ために行なった実験回路を示す模式図、図３は本発明の
人工腎臓の一例を示す断面図である。[Example] Fig. 1 is a sectional view showing an example of the header shape according to the present invention, Fig. 2 is a schematic diagram showing an experimental circuit conducted to select the header shape according to the present invention, and Fig. 3 is a cross-sectional view showing an example of the header shape according to the present invention. FIG. 2 is a cross-sectional view showing an example of a kidney.
【００１７】人工腎臓１０は、図３に示す如く、円筒状
のケーシング１１内に多数の中空糸１２を装填され、中
空糸束１３の両端部をケーシング１１の両端部にて充填
固化されるポッティング樹脂の隔壁部材１４、１５によ
り支持する。As shown in FIG. 3, the artificial kidney 10 is a potting in which a large number of hollow fibers 12 are loaded into a cylindrical casing 11, and both ends of the hollow fiber bundle 13 are filled and solidified at both ends of the casing 11. It is supported by resin partition members 14 and 15.
【００１８】各中空糸１２の開口部は隔壁部材１４、１
５の外端面に開口され、各中空糸１２の開口部全体を包
囲する漏斗状ヘッダー１６、１７の大径被着口部１６Ａ
、１７Ａがケーシング１１の両端部に接着又は螺着等に
て被着される。尚、１８、１９はＯリング等のシール部
材である。The opening of each hollow fiber 12 is connected to the partition member 14, 1.
5, and surrounds the entire opening of each hollow fiber 12.
, 17A are attached to both ends of the casing 11 by gluing or screwing. Note that 18 and 19 are sealing members such as O-rings.
【００１９】ヘッダー１６の小径接続口部１６Ｂには血
液循環回路が接続されて各中空糸１２の開口部に連通す
る血液流入ポート２１が設けられ、ヘッダー１７の小径
接続口部１７Ｂには血液循環回路が接続されて各中空糸
１２の開口部に連通する血液流出ポート２２が設けられ
る。また、ケーシング１１の隔壁部材１５寄りに位置す
る接続口部１１Ａには中空糸束１３の周囲の空間に連通
する透析液流入ポート２３が設けられるとともに、隔壁
部材１４寄りに位置する接続口部１１Ｂには中空糸束１
３の周囲の空間に連通する透析液流出ポート２４が設け
られる。A blood circulation circuit is connected to the small-diameter connection port 16B of the header 16, and a blood inflow port 21 that communicates with the opening of each hollow fiber 12 is provided, and a blood circulation circuit is connected to the small-diameter connection port 17B of the header 17. A blood outflow port 22 is provided to which a circuit is connected and communicates with the opening of each hollow fiber 12. Further, a dialysate inflow port 23 communicating with the space around the hollow fiber bundle 13 is provided in the connection port 11A of the casing 11 located near the partition member 15, and a connection port 11B located near the partition member 14 is provided. 1 hollow fiber bundle
A dialysate outflow port 24 is provided which communicates with the space around 3.
【００２０】即ち、人工腎臓１０にあっては、血液流入
ポート２１から流入して血液流出ポート２２から流出す
る血液の図において下向流と、透析液流入ポート２３か
ら流入して透析液流出ポート２４から流出する透析液の
図において上向流とを、多数の中空糸１２の半透膜を介
して互いに物質移動せしめる。That is, in the artificial kidney 10, blood flows downward from the blood inflow port 21 and flows out from the blood outflow port 22, and blood flows downward from the dialysate inflow port 23 and flows out from the dialysate outflow port. The upward flow in the diagram of the dialysate flowing out from the hollow fibers 24 causes mass transfer to each other through the semipermeable membranes of the plurality of hollow fibers 12.
【００２１】尚、人工腎臓１０において、ケーシング１
１、ヘッダー１６、１７は例えばポリプロピレン、ポリ
カーボネート等の硬質合成樹脂材料等にて構成される。[0021] In the artificial kidney 10, the casing 1
1. The headers 16 and 17 are made of a hard synthetic resin material such as polypropylene or polycarbonate.
【００２２】また、隔壁部材１４、１５は、例えばポリ
ウレタン、シリコーン等の合成樹脂材料等にて構成され
る。The partition members 14 and 15 are made of a synthetic resin material such as polyurethane or silicone.
【００２３】また、中空糸１２は、例えば、人工腎臓の
場合は再生セルロース、人工肺の場合はポリプロピレン
等から構成され、人工腎臓の場合は、内径約 ２００μ
、肉厚 ７〜１５μの半透膜を形成する。中空糸束１３
は、例えば５００ 〜１７，０００本の中空糸１２の集
合体である。The hollow fibers 12 are made of, for example, regenerated cellulose in the case of an artificial kidney, polypropylene in the case of an artificial lung, and have an inner diameter of about 200 μm in the case of an artificial kidney.
, forming a semipermeable membrane with a wall thickness of 7 to 15 μm. Hollow fiber bundle 13
is an assembly of, for example, 500 to 17,000 hollow fibers 12.
【００２４】然して、上記人工腎臓１０において、血液
が流入するヘッダー１６内で血液の偏流及び滞溜をなく
し、血栓の発生を見ることなく、良好な血液処理性能を
確保することを目的として、以下の如くの実験を行なっ
た。[0024] In the artificial kidney 10, in order to eliminate uneven flow and stagnation of blood in the header 16 into which blood flows, and to ensure good blood processing performance without the occurrence of thrombus, the following steps have been taken. I conducted an experiment like this.
【００２５】この実験においては、図１に示す如く、ヘ
ッダー１６の被着口部１６Ａ内径をＤとし、ヘッダー１
６の被着口部１６Ａから接続口部１７Ｂまでの高さをＨ
とした。また、上記ヘッダー１６の内面は、図１に示す
如く、被着口部１６Ａ側の略テーパ部１６Ｔと、接続口
部１６Ｂ側の略ストレート部１６Ｓとを、アール部にて
連続化して構成し、略テーパ部１６Ｔの勾配をθ、略ス
トレート部１６Ｓの頂角をφとし、アール部の曲率半径
をｒとした。In this experiment, as shown in FIG. 1, the inner diameter of the opening 16A of the header 16 was set to
6, the height from the attachment port 16A to the connection port 17B is H.
And so. Further, as shown in FIG. 1, the inner surface of the header 16 has a substantially tapered portion 16T on the side of the receiving port 16A and a substantially straight portion 16S on the side of the connection port 16B, which are continuous at a rounded portion. , the slope of the substantially tapered portion 16T is θ, the apex angle of the substantially straight portion 16S is φ, and the radius of curvature of the rounded portion is r.
【００２６】即ち、人工腎臓１０のヘッダー１６、１７
に図２に示す如くの血液循環回路を接続した。３０はポ
ンプ、３１は牛血貯溜槽、３２は生理食塩水貯溜槽であ
る。そして、表１に示す４種類のヘッダー１６を用意し
、表２に示す条件にて牛新鮮血循環試験を実施し、循環
可能時間及びヘッダー１６の内面における血栓の付着状
況を観察した。That is, the headers 16 and 17 of the artificial kidney 10
A blood circulation circuit as shown in FIG. 2 was connected to the tube. 30 is a pump, 31 is a bovine blood reservoir, and 32 is a physiological saline reservoir. Then, four types of headers 16 shown in Table 1 were prepared, and a bovine fresh blood circulation test was conducted under the conditions shown in Table 2, and the circulation time and the state of thrombus adhesion on the inner surface of the header 16 were observed.
【００２７】尚、現在までの実験では、牛新鮮血は ５
時間以上循環すると、牛血の活性が失われてしまうため
、試験時間は最大 ５時間を目安とした。また、循環可
能時間の判定については、ＰＢｉ（血液流入側における
圧力）が初期のＰＢｉより５０ｍｍＨｇ上昇したタイミ
ングを循環可能限界として定めた。[0027] In the experiments to date, fresh bovine blood has a
Since bovine blood loses its activity if it circulates for more than an hour, the test time was set at a maximum of 5 hours. Regarding the determination of the circulation possible time, the timing when PBi (pressure on the blood inflow side) rose by 50 mmHg from the initial PBi was determined as the circulation possible limit.
【００２８】試験結果を表３に示す。The test results are shown in Table 3.
【００２９】[0029]
【表１】[Table 1]
【００３０】[0030]
【表２】[Table 2]
【００３１】[0031]
【表３】 本発明者は、以上の実験の結果下記■〜■を認めた。[Table 3] As a result of the above experiment, the present inventor recognized the following points 1 to 2.
【００３２】■０．８ ≦Ｈ／Ｄ≦１．３ において、
血液循環回路からヘッダー内に導入される血液の流線を
ヘッダー軸心方向に規制する、ヘッダー高さ方向経路（
特に略ストレート部１６Ｓの経路）長さが、適度となる
（０．９ ≦Ｈ／Ｄ≦１．１ であれば、より適度とな
る）。このため、血液はヘッダー１６内にてヘッダー軸
心方向に沿う適度なストレート流れとなるように整流さ
れる。■0.8≦H/D≦1.3,
The header height direction path (
In particular, the length (path) of the substantially straight portion 16S is appropriate (if 0.9≦H/D≦1.1, the length is more appropriate). Therefore, the blood is rectified in the header 16 so that it flows appropriately straight along the header axial direction.
【００３３】■１８度≦φ≦２２度において、上記■に
より整流される血液の流れが、ヘッダー１６内の略スト
レート部１６Ｓを経るに際し、均一な拡がりを持ちなが
ら、中空糸１２の開口部へ進み、血液を中空糸１２へと
導入せしめる。■ At 18 degrees ≦ φ ≦ 22 degrees, the blood flow rectified by the above method (②) spreads uniformly as it passes through the substantially straight section 16S in the header 16 and flows toward the opening of the hollow fiber 12. The blood is then introduced into the hollow fibers 12.
【００３４】■θ≦ ７度において、ヘッダー１６内の
周辺部分である略テーパ部１６Ｔの勾配が浅くなり、血
液の周辺部分での線速度を上げ、結果として血液の流速
を周辺部分においても低下することなく、血液を中空糸
１２へと導入せしめる。■When θ≦7 degrees, the slope of the approximately tapered portion 16T, which is the peripheral portion in the header 16, becomes shallower, increasing the linear velocity of blood in the peripheral portion, and as a result, decreasing the flow velocity of blood also in the peripheral portion. The blood is introduced into the hollow fibers 12 without any process.
【００３５】■上記■の略ストレート部１６Ｓと、上記
■の略テーパ部１６Ｔとを、最大曲率半径のアール部に
て外挿し、連続化することにより、ヘッダー１６内に血
液の偏流と滞溜のない、より均一な流れを形成できる。[0035] By extrapolating the substantially straight part 16S of the above (■) and the substantially tapered part 16T of the above (2) at the rounded part of the maximum radius of curvature and making them continuous, uneven flow and accumulation of blood in the header 16 can be prevented. A more uniform flow can be created without
【００３６】■上記■〜■により、血液はヘッダー１６
内に偏流を生ずることなく、結果として、ヘッダー１６
内に滞溜部を生ずることがなく、血栓の発生をみること
がない。よって、良好な血液処理性能を確保できる。[0036] ■ According to the above ■ ~ ■, the blood is in header 16
As a result, the header 16
There is no stagnation within the body, and there is no possibility of thrombus formation. Therefore, good blood processing performance can be ensured.
【００３７】[0037]
【発明の効果】以上のように本発明によれば、中空糸型
物質移動装置において、第１物質が流入するヘッダー内
で第１物質の偏流及び滞溜をなくし、沈殿物又は堆積物
の生成を見ることなく、良好な物質処理性能を確保する
ことができる。As described above, according to the present invention, in a hollow fiber type mass transfer device, uneven flow and accumulation of the first substance in the header into which the first substance flows can be eliminated, and the formation of precipitates or deposits can be prevented. Good material processing performance can be ensured without causing any problems.
【図１】図１は本発明に係るヘッダー形状の一例を示す
断面図である。FIG. 1 is a sectional view showing an example of a header shape according to the present invention.
【図２】図２は本発明に係るヘッダー形状を選定するた
めに行なった実験回路を示す模式図である。FIG. 2 is a schematic diagram showing an experimental circuit used to select a header shape according to the present invention.
【図３】図３は本発明の人工腎臓の一例を示す断面図で
ある。FIG. 3 is a sectional view showing an example of the artificial kidney of the present invention.
１０ 人工腎臓 １１ ケーシング １２ 中空糸 １３ 中空糸束 １４ 隔壁部材 １５ 隔壁部材 １６ ヘッダー １７ ヘッダー １６Ａ 被着口部 １６Ｂ 接続口部 １６Ｔ 略テーパ部 １６Ｓ 略ストレート部 ２１ 血液流入ポート ２２ 血液流出ポート ２３ 透析液流入ポート ２４ 透析液流出ポート 10 Artificial kidney 11 Casing 12 Hollow fiber 13 Hollow fiber bundle 14 Partition wall member 15 Partition wall member 16 Header 17 Header 16A Adhering opening part 16B Connection port 16T substantially tapered part 16S Almost straight part 21 Blood inflow port 22 Blood outflow port 23 Dialysate inflow port 24 Dialysate outflow port
Claims (2)
れ、該中空糸束の端部が該ケーシングの端部の隔壁部材
により支持されて各中空糸の開口部が該隔壁部材の外端
面に開口され、各中空糸の開口部全体を包囲する少なく
とも１つの漏斗状ヘッダーの大径被着口部が該ケーシン
グの端部に接続され、該ヘッダーの小径接続口部には第
１物質循環回路が接続され、該ケーシングに設けた接続
口部には該中空糸束の周囲の空間に連通する少なくとも
１つの第２物質循環回路が接続されて構成される中空糸
型物質移動装置において、該ヘッダーの内面が、該被着
口部側の略テーパ部と、該接続口部側の略ストレート部
とを、アール部にて連続化したものであり、該ヘッダー
の被着口部内径をＤとし、該ヘッダーの該被着口部から
該接続口部までの高さをＨとし、該略テーパ部の勾配を
θとし、該略ストレート部の頂角をφとするとき、０．
８ ≦Ｈ／Ｄ≦１．３ 、θ≦７ 度、１８度≦φ≦２
２度であることを特徴とする中空糸型物質移動装置。Claim 1: A large number of hollow fibers are loaded in a casing, the ends of the hollow fiber bundle are supported by a partition member at the end of the casing, and the opening of each hollow fiber is located on the outer end surface of the partition member. A large diameter application port of at least one funnel-shaped header which is open and surrounds the entire opening of each hollow fiber is connected to the end of the casing, and a small diameter connection port of the header is connected to a first material circulation circuit. in the hollow fiber type mass transfer device configured such that the header is connected to the header, and at least one second material circulation circuit that communicates with the space around the hollow fiber bundle is connected to the connection port provided in the casing. The inner surface of the header has a substantially tapered part on the side of the receiving port and a substantially straight part on the side of the connecting port, which are made continuous at a rounded part, and the inner diameter of the receiving port of the header is D. , when the height from the attachment port to the connection port of the header is H, the slope of the substantially tapered portion is θ, and the apex angle of the substantially straight portion is φ, 0.
8≦H/D≦1.3, θ≦7 degrees, 18 degrees≦φ≦2
A hollow fiber type mass transfer device characterized in that the temperature is 2 degrees.
記略ストレート部とを最大曲率半径にて連続化したもの
である請求項１記載の中空糸型物質移動装置。2. The hollow fiber type mass transfer device according to claim 1, wherein the rounded portion is formed by making the substantially tapered portion and the substantially straight portion continuous at a maximum radius of curvature.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9485891A JPH04305229A (en) | 1991-04-02 | 1991-04-02 | Hollow yarn type mass-transfer device |
| DE69115204T DE69115204T2 (en) | 1990-09-27 | 1991-09-27 | Hollow fiber mass transfer device. |
| EP91116538A EP0477966B1 (en) | 1990-09-27 | 1991-09-27 | Hollow fiber mass transfer apparatus |
| US07/887,609 US5238561A (en) | 1990-09-27 | 1992-05-22 | Hollow fiber mass transfer apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9485891A JPH04305229A (en) | 1991-04-02 | 1991-04-02 | Hollow yarn type mass-transfer device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH04305229A true JPH04305229A (en) | 1992-10-28 |
Family
ID=14121734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9485891A Withdrawn JPH04305229A (en) | 1990-09-27 | 1991-04-02 | Hollow yarn type mass-transfer device |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH04305229A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07184994A (en) * | 1993-12-28 | 1995-07-25 | Nikkiso Co Ltd | Hollow fiber blood processing device |
| WO2000012154A1 (en) * | 1998-08-27 | 2000-03-09 | Toray Industries, Inc. | Blood processing device |
| JP2016123820A (en) * | 2015-01-08 | 2016-07-11 | ニプロ株式会社 | Cap for blood apparatus and blood apparatus |
| WO2016159375A1 (en) * | 2015-04-03 | 2016-10-06 | 旭化成メディカル株式会社 | Hollow fiber membrane blood purifying device |
-
1991
- 1991-04-02 JP JP9485891A patent/JPH04305229A/en not_active Withdrawn
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07184994A (en) * | 1993-12-28 | 1995-07-25 | Nikkiso Co Ltd | Hollow fiber blood processing device |
| WO2000012154A1 (en) * | 1998-08-27 | 2000-03-09 | Toray Industries, Inc. | Blood processing device |
| US6409024B1 (en) | 1998-08-27 | 2002-06-25 | Toray Industries, Inc. | Blood processing device |
| JP2016123820A (en) * | 2015-01-08 | 2016-07-11 | ニプロ株式会社 | Cap for blood apparatus and blood apparatus |
| WO2016159375A1 (en) * | 2015-04-03 | 2016-10-06 | 旭化成メディカル株式会社 | Hollow fiber membrane blood purifying device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A300 | Application deemed to be withdrawn because no request for examination was validly filed |
Free format text: JAPANESE INTERMEDIATE CODE: A300 Effective date: 19980711 |