JPH0429906A - Artificial tooth stabilizer - Google Patents

Abstract

PURPOSE:To provide the title improved stabilizer free from such problems as discomfort, offensive taste, oral stickiness and adhesive force, comprising a dimethylpolysiloxane of a specified viscosity and a water-soluble polymer. CONSTITUTION:The objective artificial tooth stabilizer comprising (A) 40-99wt.% of a compound of the formula (R1 and R2 are each CH3 or OH; (n) is >=40) with 50-15000000 (pref. 100-10000000) cps in the viscosity at 25 deg.C and (B) 1-60wt.% of a water-soluble polymer (e.g. karaya gum, carboxymethylcellulose sodium salt, polyethylene oxide). The present stabilizer gives no offensive taste when used, being excellent in adhesiveness for a long period of time, and also excellent in releaseability from artificial teeth after use. If desired, this stabilizer may further be incorporated with other organopolysiloxane(s).

Description

DETAILED DESCRIPTION OF THE INVENTION Field of the Invention The present invention relates to a paste-like denture stabilizer used for fixing dentures.

BACKGROUND OF THE INVENTION Various denture adhesives have been known to date, and are broadly classified into powder-like and paste-like products. Powdered ones are
Water-soluble natural polymer substances, such as karaya gum,
The main component is semi-synthetic polymeric substances such as sodium carboxymethylcellulose and sodium polyacrylate. In addition, paste-like products are made by mixing water-soluble polymeric substances with petrolatum, etc.
There are two main types: cream paste type) and paste made from vinyl acetate etc. and water-alcohol (vinyl acetate paste type). However, these denture adhesives have several problems.

For example, when using a powdered material, the powder scatters during use and ends up sticking to areas other than the intended denture. In addition, since it dissolves easily in saliva, the duration of denture fixation is short, and (2) it is necessary to apply it at least once a day to maintain adhesion to the molecules during the day.

A water-soluble polymer cream paste type product has a longer fixation duration than a powdered product, but it must be applied at least once a day to maintain adhesion to the molecules throughout the day. In addition, the inside of the mouth becomes oily during use, and after use, Vaseline remains throughout the day, causing discomfort.

Vinyl acetate paste type has a fixed duration of 1
Although it lasts for more than a few days, it is highly compatible with dentures and sticks to the dentures after use, making it extremely difficult to remove. There is also a pungent, bad taste from the alcohol that migrates from the denture adhesive into your saliva. These bad tastes are indescribable and cannot be avoided as long as the denture adhesive is used during the day, not only when eating or drinking but also when not eating or drinking.

Among these problems, in order to solve the bad taste during use and the ease of peeling from the denture after use, 1 million cp at 20℃ was used.
A denture stabilizer made of dimethylpolysiloxane with a molecular weight of s or more has been proposed (Japanese Patent Application No. 1308234).

However, since dimethylpolysiloxane exhibits water repellency, during use, it may become immersed in water from the oral mucosa.
Since it peels off more easily than the oral mucosa, there is a need for an improved denture stabilizer that has a bad taste during use, has excellent adhesive properties over a long period of time, and has excellent peelability from dentures after use.

Means for Solving the Problems The denture stabilizer of the present invention further improves the problems of the conventional denture stabilizers described above, and is made of dimethylpolysiloxane with a viscosity of 50 to 15 million centipoise (cps) at 25°C and a water-soluble denture stabilizer. It is made by blending a polymeric substance.

The dimethylpolysiloxane used has the general formula: [wherein R1
and R2 is a methyl group or a hydroxyl group, and n is a dimethylsolane group average polymerization number, which is usually 40 or more.
million cps, preferably 100-+0 million cps
belongs to. If the viscosity at 25°C is less than 50 cps, it will only protrude from the denture during use;
If it exceeds 5 million cps, it becomes difficult to apply it to dentures.

Such dimethylpolysiloxanes are well known and commercially available, such as those sold by Toray Nlicon Co., Ltd. under the trade name rsH200 Oil. Further, in the present invention, in addition to using dimethylpolysiloxane having a predetermined viscosity alone, two or more types of dimethylpolysiloxane may be used in combination to obtain a predetermined viscosity.

The amount of dimethylpolysiloxane blended is preferably 40 to 99% by weight based on the total amount of the denture stabilizer. If it is less than 40% by weight, it will be difficult to apply to dentures, and if it exceeds 99% by weight, it will become water-soluble. The adhesive properties of the polymer are poor, making it impossible to keep dentures in place for long periods of time.

As the water-soluble polymeric substance, any of natural polymeric substances, semi-synthetic polymeric substances, and synthetic polymeric substances can be used alone or in combination of two or more.

Preferable natural polymer substances include karaya gum, gelatin, and arahya gum; vegetable gums such as tragacanth gum, locust bean gum, and guar gum; agar; seaweed extracts such as carrageenan; amylose, dextrin, dextran, pullulan, and xanthan gum. It can also be used.

As the semi-synthetic polymer, carboxymethylcellulose sodium and sodium alginate are preferred, and methylcellulose, ethylcellulose, and hydroquineethylcellulose can also be used.

Preferred synthetic polymers include polyethylene oxide, storium polyacrylate, methylhinyl ether/maleic anhydride copolymer or maleic anhydride copolymer and its salts, polyvinylpyrrolidone, ethyl acrylate, styrene, vinyl acetate, and other copolymers. water-soluble copolymers with monomers that can be copolymerized with polyhinyl alcohol, partially hydrolyzed polyhinyl acetate, or monomers that can be copolymerized with hynyl acetate, such as acrylic acid, methacrylic acid , crotonic acid, or copolymers of their esternes, polyhinylphosphonic acid, polyhinylphosphonic acid, polyitaconic acid, polyhinylcarpoquinamide, e.g. polyacrylamide, styrene and maleic anhydride. A copolymer, a copolymer of ethylene and maleic anhydride, a copolymer of acrylamide and acrylic acid, etc. can be used.

The blending amount of the water-soluble polymeric substance is preferably 1 to 60% by weight based on the total amount of the denture stabilizer; if it is less than 1% by weight, the adhesion of the water-soluble polymeric substance cannot be exhibited;
If the amount exceeds 100%, it will be difficult to spread the coating onto the dentures.

The denture stabilizer of the present invention may optionally contain other organopolysiloxanes, such as safety to living organisms, colorless and transparent appearance suitable as a denture stabilizer, ease of availability, etc. Therefore, methylhydrodiene polysiloxane, methylphenylpolysiloxane can be blended, and in addition, methylpolycyclosiloxane, alkyl-modified silicone, amino-modified silicone, epoxy-modified silicone, carboxyl-modified silicone, chloroalkyl-modified silicone, alkyl higher alcohol ester-modified silicone, Alcohol-modified silicone, polyether-modified silicone, or fluorine-modified silicone may be used alone or in combination.
It is also possible to use more than one species in combination. In this case, the viscosity of the dimethylpolysiloxane and the mixed fraction of these organopolysiloxanes is 50 cps or more at 25°C.

The denture adhesive of the present invention can be produced in the same manner as a normal viscous paste using equipment such as a kneader-1, a mixer, and the like. For example, dimethylpolysiloxane, water-soluble polymeric substances, organic powders, inorganic powders, and optionally additives such as colorants, flavoring agents, and fungicides are kneaded until uniform. . When the dimethylpolysiloxane fraction consists of a low viscosity dimethylpolysiloxane (e.g. viscosity 10,000 cps at 25°C) and a high viscosity dimethylpolysiloxane (e.g. viscosity 10 million cps at 25°C), the low viscosity dimethylpolysiloxane has a high water solubility. Preferably, the molecular substance is dispersed, added to the high viscosity dimethylpolysiloxane, and kneaded.

The present invention will be explained in more detail with reference to Examples below, but the present invention is not limited thereto. All "%" are "% by weight".

Example 1-17 According to the formulation shown in Table 1, each component was uniformly kneaded in a mortar to produce a denture stabilizer, and its performance was evaluated. The results are shown in Table 1.

Each evaluation in Table 1 was performed by the following method.

(1) Viscosity of dimethylpolysiloxane A Brookfield HBT viscometer was installed on a Helibus stand (Helibus stand).
The viscosity was measured using a TF spindle at a rotation speed of 2 and 5 rpm.

The measurements were performed in a constant temperature room at 25°C. In this system, 32
Although it can measure up to 1,000,000 centipoise, the measurement accuracy is poor below 1% of the full scale viscosity (320,000 centipoise), so we used a BL type viscometer manufactured by Tokyo Keiki Co., Ltd., No. 40 star, rotation speed 6 rpm. Measured at

(2) Applying to dentures An appropriate amount of denture stabilizer was applied to a methacrylic resin maxillary complete denture according to a conventional method, and the ease of application was sensory evaluated using the following criteria.

○: Easy, △: Slightly difficult, ×: Difficult.

(3) Taste The denture adhesive was placed in the mouth, and the presence or absence of a bad taste was sensory evaluated using the following criteria.

○: No bad taste, △: Slightly bad taste, ×: Bad taste.

(4) Adhere an appropriate amount of denture stabilizer to an adhesive methacrylic resin maxillary complete denture according to a conventional method, and place it in the oral cavity.

The adhesiveness of the complete denture after 8 hours was sensory evaluated using the following criteria.

○: Good, △: Slightly poor, ×: Poor.

(5) Ease of removal from dentures An appropriate amount of denture stabilizer was attached to a methacrylic resin denture according to a conventional method, and the dentures were immersed in water at 25° C. for 2 hours. Thereafter, the denture adhesive was removed from the denture, and the ease of removal was sensory evaluated using the following criteria.

O: Easy, △: Slightly difficult, ×: Difficult.

(6) Ease of removal from oral mucosa Take 1 to 2 g of denture adhesive, attach it to the human maxillary oral mucosa, leave it for 1 minute, and then remove the denture adhesive with your fingers.
Ease of removal was sensory evaluated using the following criteria.

○: Easy, △: Slightly difficult, ×: Difficult.

(7) Stickiness of saliva during use A suitable amount of denture stabilizer is attached to the maxillary complete denture made of methacrylic resin according to a conventional method, and the denture is placed in the oral cavity. The stickiness of saliva after 1 hour was sensory evaluated according to the following criteria.

O: Not sticky, △: Slightly sticky, ×: Sticky.

(8) Protruding from the denture An appropriate amount of denture stabilizer was attached to the maxillary complete denture made of methacrylic resin according to a conventional method, and the denture was placed in the oral cavity. Sensory evaluation was conducted to determine whether the denture adhesive protrudes from between the denture and the gums during use according to the following criteria.

○: None, △: Slightly present, ×: Present.

(9) Comprehensive evaluation The evaluation results of (2) to (8) were comprehensively evaluated in four stages according to the following criteria.

A: 1 or less △ and × is O B: 2 to 3 △ and × is O C: 4 or more △ and × is O or 1 × D: × is 2
As shown in Table 1, the denture adhesive of the present invention has desirable performance.

Effects of the Invention According to the present invention, an improved denture adhesive can be obtained that is free from problems such as discomfort, bad taste, stickiness in the mouth, and adhesive strength.

Claims (1)

[Claims] (1) A denture stabilizer comprising dimethylpolysiloxane and a water-soluble polymer substance having a viscosity of 50 to 15 million centipoise at 25°C.