JPH0427866B2 - - Google Patents
Info
- Publication number
- JPH0427866B2 JPH0427866B2 JP58124921A JP12492183A JPH0427866B2 JP H0427866 B2 JPH0427866 B2 JP H0427866B2 JP 58124921 A JP58124921 A JP 58124921A JP 12492183 A JP12492183 A JP 12492183A JP H0427866 B2 JPH0427866 B2 JP H0427866B2
- Authority
- JP
- Japan
- Prior art keywords
- blood
- access device
- present
- blood vessel
- passage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008280 blood Substances 0.000 claims description 46
- 210000004369 blood Anatomy 0.000 claims description 46
- 210000004204 blood vessel Anatomy 0.000 claims description 18
- 239000000463 material Substances 0.000 description 9
- 238000000034 method Methods 0.000 description 6
- 229920001971 elastomer Polymers 0.000 description 4
- -1 polytetrafluoroethylene Polymers 0.000 description 4
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 4
- 239000004810 polytetrafluoroethylene Substances 0.000 description 4
- 231100000614 poison Toxicity 0.000 description 3
- 239000003440 toxic substance Substances 0.000 description 3
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 230000003872 anastomosis Effects 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 2
- 239000000806 elastomer Substances 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 238000001631 haemodialysis Methods 0.000 description 2
- 230000000322 hemodialysis Effects 0.000 description 2
- 229920000728 polyester Polymers 0.000 description 2
- 239000005060 rubber Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000002785 anti-thrombosis Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 229940109239 creatinine Drugs 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000004731 jugular vein Anatomy 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 239000012229 microporous material Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920002492 poly(sulfone) Polymers 0.000 description 1
- 229920002338 polyhydroxyethylmethacrylate Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 229940045136 urea Drugs 0.000 description 1
- 229940116269 uric acid Drugs 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 239000002759 woven fabric Substances 0.000 description 1
Landscapes
- External Artificial Organs (AREA)
Description
【発明の詳細な説明】
本発明は、ブラツド・アクセス装置に関する。
さらに詳しくは、コンパクトで装着時の違和感の
少ないブラツド・アクセス装置に関する。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a brad access device.
More specifically, the present invention relates to a blood access device that is compact and does not cause discomfort when worn.
医療分野においては、しばしば血管系を身体外
部に連結する必要が生ずる場合がある。例えば腎
不全の患者は、クレアチニン、尿酸、尿素等の毒
性物質を排泄する機能が低下し、血液中に毒性物
質の蓄積が起こるので、１週間に２〜３度、透析
により毒性物質を除去する必要があるが、血液透
析には血管より血液を体外へ導出する操作及び浄
化した血液を再び血管より体内へ返す操作が含ま
れている。また、近年血液透析以外にも吸着法や
血漿交換法などによつて血液中の毒性物質や有害
物質を除去することにより病気の治療を行う方法
が成果をあげつつあり、血液を体外へ導出して適
当な処理を行つた後、再び体内へ返す操作は、今
後さらに増加する傾向にある。このような場合、
従来は直接血管に針を穿刺したり、あるいはシヤ
ントを設ける方法が行われてきたが、これらの方
法はいずれも種々の問題点を有しており、その改
良が望まれている。すなわち、針を直接血管に穿
刺する方法は、患者に対して苦痛を与えるばかり
でなく、繰り返し行うと血管を損傷し、血流が得
られなくなるようになる。また、動脈と静脈を短
絡させるシヤントの場合、動脈と静脈にチユーブ
を挿入して体外で結合させる外シヤントは、チユ
ーブに血栓ができやすい欠点があり、動脈と静脈
を手術により吻合させ、吻合部に穿刺する内シヤ
ントは、穿刺時に苦痛を伴なうとともに、繰り返
し穿刺しているとしだいに吻合部が硬化して遂に
は針を挿入できなくなる。また、シヤントを形成
すると手足の末端部分への血液の循環が減少する
ので、長い間には生体に何らかの悪影響を与える
恐れがある。 In the medical field, it is often necessary to connect the vascular system to the outside of the body. For example, in patients with renal failure, the ability to excrete toxic substances such as creatinine, uric acid, and urea decreases, causing accumulation of toxic substances in the blood, so toxic substances should be removed through dialysis two to three times a week. Although necessary, hemodialysis includes the operation of drawing blood out of the body through a blood vessel and the operation of returning the purified blood back into the body through the blood vessel. In addition to hemodialysis, methods for treating diseases by removing toxic and harmful substances from the blood, such as adsorption methods and plasma exchange methods, have recently become successful. The number of operations in which materials are returned to the body after appropriate treatment is likely to increase further in the future. In such a case,
Conventionally, methods of directly puncturing a blood vessel with a needle or providing a shunt have been used, but all of these methods have various problems, and improvements are desired. That is, the method of directly puncturing a blood vessel with a needle not only causes pain to the patient, but also damages the blood vessel when repeated, making it impossible to obtain blood flow. In addition, in the case of shunts that short-circuit arteries and veins, external shunts that insert tubes into arteries and veins and connect them outside the body have the disadvantage that blood clots are likely to form in the tubes. The internal needle puncture causes pain during puncture, and repeated punctures gradually harden the anastomosis, eventually making it impossible to insert the needle. In addition, the formation of a shunt reduces blood circulation to the distal parts of the limbs, which may have some negative effects on the living body over a long period of time.
上述した問題点を解決せんがために、特公昭57
−45591号公報においては、血管の側面に取り付
けるためのフランジを備えたブラツド・アクセス
装置が提案されている。かかる装置を用いれば上
述した問題点は一応解決できるものの、装置が複
雑で嵩張り、血液の導出、導入の操作も煩雑な欠
点を有している。 In order to solve the above-mentioned problems, the special public
Japanese Patent No. 45591 proposes a blood access device equipped with a flange for attachment to the side of a blood vessel. Although the above-mentioned problems can be solved by using such a device, it has the disadvantage that the device is complicated and bulky, and the operations for drawing out and introducing blood are complicated.
本発明者らは、上記のブラツド・アクセス装置
の欠点を改良すべく種々検討した結果、可撓性を
有する材料で血液通路を形成し、特定構成の閉止
機構を設けることにより、フランジ等を設けなく
ても生体組織との癒着がきわめて良好で小型化で
き、装着した際に患者へ与える違和感の少ないブ
ラツド・アクセス装置が得られることを見い出
し、本発明に到達した。すなわち本発明の目的
は、患者に苦痛を与えることなく長期にわたつて
安全に使用することのできるブラツド・アクセス
装置を提供することにある。また他の目的は、血
液の導出、導入操作がきわめて簡単なブラツド・
アクセス装置を提供することにある。さらに他の
目的は、小型で人体への装着感の良好なブラツ
ド・アクセス装置を提供することにある。 As a result of various studies to improve the drawbacks of the blood access device described above, the inventors of the present invention formed a blood passage using a flexible material, provided a closing mechanism with a specific configuration, and provided a flange, etc. The present inventors have discovered that even without this device, a blood access device can be obtained that has extremely good adhesion to living tissue, can be miniaturized, and causes less discomfort to the patient when worn, and has thus arrived at the present invention. That is, an object of the present invention is to provide a blood access device that can be used safely over a long period of time without causing pain to the patient. Another purpose is to use a blood pump that is extremely easy to draw out and introduce blood into.
The objective is to provide an access device. Still another object is to provide a blood access device that is small and comfortable to wear on the human body.
本発明のブラツド・アクセス装置は、血管の側
面に連結するための可撓性を有する血液通路と、
該血液通路の血管との連結部付近を圧迫して狭窄
し、血液通路を閉止する弾性体とを備えてなるこ
とを特徴とする。本発明においては、血液通路が
可撓性材料で形成されているので、生体組織との
癒着がきわめて良好である。また可撓性があり、
且つきわめて小型化できるので、装着後の違和感
が少なく、長期にわたつて快適に使用することが
できる。 The blood access device of the present invention includes a flexible blood passage for connection to the side of a blood vessel;
It is characterized by comprising an elastic body that compresses and narrows the blood passageway near the connecting portion with the blood vessel, thereby closing the blood passageway. In the present invention, since the blood passage is formed of a flexible material, adhesion with living tissue is extremely good. It is also flexible,
Moreover, since it can be extremely miniaturized, there is little discomfort after wearing it, and it can be used comfortably for a long period of time.
本発明のブラツド・アクセス装置の血液通路を
形成する可撓性材料としては、各種のプラスチツ
ク、ゴムなどが使用可能であるが、血液親和性に
優れた材料が好ましい。このような材料を例示す
るならば、ポリテトラフロロエチレン、ポリウレ
タン、ポリエステル、ポリヒドロキシエチルメタ
クリレート、ポリスルホン、シリコーン、ゴムな
どをあげることができる。これらのなかでも、生
体組織との癒着性の点で微細多孔構造のものや織
物または編物が好ましい。特に好ましい材料は、
ポリテトラフロロエチレンからなる微細多孔体及
びポリエステルからなる織物や編物である。また
これらの材料の生体親和性や抗血栓性を高めるた
めに、表面に他の物質をコーテイングしたり、あ
るいは化学処理を行つてもよい。血液通路として
は、これらの材料からなるチユーブ状のものを通
常は使用する。 As the flexible material forming the blood passage of the blood access device of the present invention, various types of plastics, rubbers, etc. can be used, but materials with excellent blood affinity are preferred. Examples of such materials include polytetrafluoroethylene, polyurethane, polyester, polyhydroxyethyl methacrylate, polysulfone, silicone, and rubber. Among these, those with a microporous structure, woven fabrics, or knitted fabrics are preferred from the viewpoint of adhesion to living tissues. Particularly preferred materials are
These are microporous materials made of polytetrafluoroethylene and woven or knitted fabrics made of polyester. Further, in order to enhance the biocompatibility and antithrombotic properties of these materials, the surface may be coated with other substances or chemically treated. A tube-shaped tube made of these materials is usually used as a blood passage.
血液通路を圧迫して狭窄し閉止する弾性体とし
ては、エラストマーやバネなどをあげることがで
きる。特にエラストマーを使用すれば、きわめて
構造が単純な狭窄機構を提供することができるの
で好ましい。 Elastomers, springs, and the like can be used as the elastic body that compresses the blood passage to narrow it and close it. In particular, the use of elastomers is preferred since it allows a constriction mechanism with a very simple structure to be provided.
以下図面に基づいて本発明のブラツド・アクセ
ス装置をさらに詳細に説明する。第１図及び第２
図は本発明のブラツド・アクセス装置の１実施例
を生体に装着した状態を示す断面図である。第１
図は血管に垂直に切断した図であり、第２図は血
管に平行に切断した図である。第１図及び第２図
に示すブラツド・アクセス装置は、血液通路とな
る可撓性チユーブ１を狭窄する機構を有するもの
であり、狭窄機構としては弾性体７による圧迫機
構を採用した例である。第１図は不使用時に可撓
性チユーブ１が弾性体７により圧迫狭窄されて閉
止された状態を示している。閉止は血管の近傍で
行われるので、血液の滞留はほとんど起こらな
い。血液を体外へ導出する場合あるいは体内へ導
入する場合には、第２図に示すように血液導出ま
たは導入回路８の先端部を１に挿入する。８を１
に挿入して１の閉止部を押し拡げることにより血
管は外部と連結され、血液の導入あるいは導出が
行われる。そして使用後は８を抜くだけで再び１
は７に圧迫されて閉止される。このように弾性体
による圧迫機構を用いたものは、きわめて簡単な
操作で繰り返し血液の導出、導入ができるので、
好ましい。 DESCRIPTION OF THE PREFERRED EMBODIMENTS The blood access device of the present invention will be explained in more detail below based on the drawings. Figures 1 and 2
The figure is a sectional view showing a state in which an embodiment of the blood access device of the present invention is attached to a living body. 1st
The figure is a view cut perpendicular to the blood vessel, and FIG. 2 is a view taken parallel to the blood vessel. The blood access device shown in FIGS. 1 and 2 has a mechanism for constricting a flexible tube 1 that serves as a blood passage, and is an example in which a compression mechanism using an elastic body 7 is used as the constriction mechanism. . FIG. 1 shows a state in which the flexible tube 1 is compressed and constricted by the elastic body 7 and closed when not in use. Since closure is performed near the blood vessel, there is little blood stagnation. When blood is to be led out of the body or introduced into the body, the distal end of the blood lead-out or introduction circuit 8 is inserted into the blood lead-out or introduction circuit 1 as shown in FIG. 8 to 1
The blood vessel is connected to the outside by inserting the blood vessel into the blood vessel and pushing open the closing portion of the blood vessel 1 to allow blood to be introduced or taken out. And after use, just pull out 8 and it will return to 1.
is compressed by 7 and closed. In this way, using a compression mechanism using an elastic body, blood can be drawn out and introduced repeatedly with extremely simple operations.
preferable.
以上述べたように、本発明のブラツド・アクセ
ス装置は、構造が簡単でコンパクトあり、きわめ
て簡単な操作で血液の導出、導入ができ、生体組
織との癒着が良好であるので、長期にわたつて安
全に使用することができる。なお、本発明の装置
を使用しないときは、接着剤で被つたり、キヤツ
プやフイルムで蓋をしておくことが好ましい。 As described above, the blood access device of the present invention has a simple and compact structure, allows blood to be drawn out and introduced with extremely simple operations, and has good adhesion to living tissue, so it can be used for a long period of time. Can be used safely. When the device of the present invention is not in use, it is preferable to cover it with adhesive or cover it with a cap or film.
以下に本発明のブラツド・アクセス装置を使用
した実験例について述べるが、本発明は実験例に
より何ら限定されるものではない。 Experimental examples using the blood access device of the present invention will be described below, but the present invention is not limited to the experimental examples in any way.
実験例
ウサギの頚静脈に、血液通路として内径２mm、
外径３mmのポリテトラフロロエチレン製微細多孔
質チユーブをサイド・エンド吻合した。そして皮
膚面にチユーブの他端を固定し、先端をシリコー
ン・ゴムにて盲管とした外径２mmのポリテトラフ
ロロエチレン製チユーブ（非多孔質）を栓体とし
て挿入した。この状態で１週間放置し、観察を行
つたが、血液の漏出や細菌感染は認められなかつ
た。１週間経過後に栓体を抜き、カテーテルを挿
入したところ、容易に採血することができた。Experimental example: In the jugular vein of a rabbit, an inner diameter of 2 mm was placed as a blood passage.
Side-end anastomosis was performed using a polytetrafluoroethylene microporous tube with an outer diameter of 3 mm. Then, the other end of the tube was fixed to the skin surface, and a polytetrafluoroethylene tube (non-porous) with an outer diameter of 2 mm was inserted as a plug, with the tip of the tube closed with silicone rubber. The specimen was left in this state for one week and observed, but no blood leakage or bacterial infection was observed. After one week, the plug was removed and a catheter was inserted, and blood could be easily collected.
第１図及び第２図は、本発明のブラツド・アク
セス装置の１実施例を生体に装着した状態を示す
断面図である。
１……血液通路、２……栓体、３……血管、４
……皮膚、７……弾性体。
FIGS. 1 and 2 are cross-sectional views showing a state in which an embodiment of the blood access device of the present invention is attached to a living body. 1...Blood passageway, 2...Blug body, 3...Blood vessel, 4
...Skin, 7...Elastic body.
Claims (1)
血液通路と、該血液通路の血管との連結部付近を
圧迫して狭窄し、血液通路を閉止する弾性体とを
備えてなることを特徴とするブラツド・アクセス
装置。1. It is characterized by comprising a flexible blood passage for connecting to the side surface of a blood vessel, and an elastic body that compresses and narrows the blood passage near the connecting part with the blood vessel, thereby closing the blood passage. Blood access device.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58124921A JPS6018175A (en) | 1983-07-09 | 1983-07-09 | Blood access apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58124921A JPS6018175A (en) | 1983-07-09 | 1983-07-09 | Blood access apparatus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6018175A JPS6018175A (en) | 1985-01-30 |
| JPH0427866B2 true JPH0427866B2 (en) | 1992-05-12 |
Family
ID=14897432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58124921A Granted JPS6018175A (en) | 1983-07-09 | 1983-07-09 | Blood access apparatus |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6018175A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4815024B1 (en) | 2010-07-02 | 2011-11-16 | 日機装株式会社 | Artificial blood vessels and artificial blood vessel access ports |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5745591A (en) * | 1980-09-03 | 1982-03-15 | Ricoh Kk | Injection charge quantity controller for electrochromatic display |
| JPS5849155A (en) * | 1981-09-18 | 1983-03-23 | 日本メデイカルエンジニアリング株式会社 | Blood introducing and discharging apparatus |
-
1983
- 1983-07-09 JP JP58124921A patent/JPS6018175A/en active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5745591A (en) * | 1980-09-03 | 1982-03-15 | Ricoh Kk | Injection charge quantity controller for electrochromatic display |
| JPS5849155A (en) * | 1981-09-18 | 1983-03-23 | 日本メデイカルエンジニアリング株式会社 | Blood introducing and discharging apparatus |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6018175A (en) | 1985-01-30 |
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