JPH0427201B2 - - Google Patents
Info
- Publication number
- JPH0427201B2 JPH0427201B2 JP61148993A JP14899386A JPH0427201B2 JP H0427201 B2 JPH0427201 B2 JP H0427201B2 JP 61148993 A JP61148993 A JP 61148993A JP 14899386 A JP14899386 A JP 14899386A JP H0427201 B2 JPH0427201 B2 JP H0427201B2
- Authority
- JP
- Japan
- Prior art keywords
- pulp
- capping agent
- dental
- dentin
- capping
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003827 pulp capping and pulpectomy agent Substances 0.000 claims description 23
- 210000003074 dental pulp Anatomy 0.000 claims description 16
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 11
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims description 11
- 239000000920 calcium hydroxide Substances 0.000 claims description 11
- 235000014653 Carica parviflora Nutrition 0.000 claims description 9
- 241000243321 Cnidaria Species 0.000 claims description 9
- 239000000843 powder Substances 0.000 claims description 7
- 239000012153 distilled water Substances 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 3
- 210000004268 dentin Anatomy 0.000 description 15
- 238000000034 method Methods 0.000 description 8
- 206010028851 Necrosis Diseases 0.000 description 5
- 206010052428 Wound Diseases 0.000 description 5
- 208000027418 Wounds and injury Diseases 0.000 description 5
- 230000017074 necrotic cell death Effects 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 239000002344 surface layer Substances 0.000 description 3
- 206010002091 Anaesthesia Diseases 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 2
- 230000037005 anaesthesia Effects 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 210000003464 cuspid Anatomy 0.000 description 2
- 208000002925 dental caries Diseases 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000004898 kneading Methods 0.000 description 2
- 231100000344 non-irritating Toxicity 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 239000011574 phosphorus Substances 0.000 description 2
- 229910052698 phosphorus Inorganic materials 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 208000034656 Contusions Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 208000034526 bruise Diseases 0.000 description 1
- 239000004568 cement Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 210000001968 dental pulp cell Anatomy 0.000 description 1
- 208000007147 dental pulp necrosis Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000010304 firing Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 229940040145 liniment Drugs 0.000 description 1
- 239000000865 liniment Substances 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 230000036407 pain Effects 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
Landscapes
- Dental Preparations (AREA)
Description
【発明の詳細な説明】
〈産業上の利用分野〉
本発明は、現今の臨床における人の歯の露髄処
置として、活性力旺盛な歯髄は可能な限り残して
置く歯髄保存治療術が行なわれているが、この時
に用いられる歯科用歯髄治療剤、即ち、覆髄剤に
関する。[Detailed Description of the Invention] <Industrial Application Field> The present invention is a method for treating the exposed pulp of human teeth in current clinical practice, in which pulp preservation treatment is carried out in which the highly active pulp is preserved as much as possible. However, the present invention relates to a dental pulp treatment agent used at this time, that is, a pulp capping agent.
〈従来の技術〉
健全な歯が、殴打、打撲で破折したり、虫歯の
治療中に切削ミスで削り過ぎて中の歯髄が露出し
た場合、あるいはまた、虫歯の進行度合が著しい
ので本来の治療のために虫歯に罹つた象牙質を削
除していくうちに歯髄が露出した場合、この露出
創面をカバーする治療法（覆髄法）と、歯髄の一
部が細菌に感染している時は、この歯髄の歯冠部
を切除して歯髄の切断創をカバーする治療法（生
活歯髄切断法）の二つがある。この露出歯髄の創
面及び切断創傷面の両方をカバーするために用い
る歯科治療用塗布剤を覆髄剤と呼ぶ。このよう
に、生きている歯髄に直接接触させる覆髄剤は歯
髄組織に対し、刺激性、為害性、腐触性、あるい
は感染性を有するものであつてはならない。理想
的な覆髄剤で歯髄がカバーされた場合、残存する
生活歯髄が外界のあらゆる刺激から保護されるよ
うな硬組織の隔壁が作られることである。即ち、
健康な歯髄は健全な象牙質で囲まれているよう
に、覆髄剤でもつて露出及び切断歯髄をカバーし
た場合、一定期間後に歯髄表層と覆髄剤との接触
面下に象牙質が形成されればこれに優るものはな
い。このように形成された象牙質は被蓋象牙質
（デンテインブリツヂ）と呼ばれて、現在のとこ
ろ、このような象牙質の形成を誘導する覆髄剤が
最良のものであると考えられている。<Conventional technology> When a healthy tooth is broken due to a blow or bruise, or when the tooth pulp is exposed due to excessive cutting due to a cutting error during the treatment of tooth decay, or when the tooth pulp has progressed to a significant degree, the original If the dental pulp is exposed while removing carious dentin for treatment, there is a treatment method that covers this exposed wound surface (pulp capping method), and a treatment method that covers the exposed wound surface (pulp capping method) and when a part of the pulp is infected with bacteria. There are two treatment methods (vital pulp cutting method) that cover the cutting wound of the pulp by cutting off the crown of the tooth pulp. The dental treatment liniment used to cover both the wound surface of the exposed pulp and the cut wound surface is called a pulp capping agent. Thus, the pulp capping agent that is brought into direct contact with the living dental pulp must not be irritating, harmful, corrosive, or infectious to the pulp tissue. When the pulp is covered with an ideal pulp capping agent, a hard tissue septum is created that protects the remaining vital pulp from all external stimuli. That is,
Just as a healthy pulp is surrounded by healthy dentin, if a pulp capping agent is used to cover the exposed or cut pulp, dentin will form under the contact surface between the pulp surface layer and the pulp capping agent after a certain period of time. There is nothing better than this. The dentin formed in this way is called dentin bridge, and at present, the best pulp-capping agent is thought to induce the formation of this kind of dentin. ing.
ヘルマン（1928年）の露出歯髄に対する覆髄剤
の研究以来、現在まで多くの人々がより良い覆髄
剤について研究を行なつているが、鎮痛作用を有
すると共に、上記のような被蓋象牙質が比較的容
易に、かつ、高率に形成される覆髄剤は、現在の
ところ、水酸化カルシウムを主成分としたもの
で、ライフ、ダイカル（商品名）がある。特に水
酸化カルシウム単味のものはより高率にデンテイ
ンブリツヂの形成が行なわれる。しかしながら、
デンテインブリツヂの形成能は確かに高率ではあ
るが、水酸化カルシウム製剤はこの特徴である高
い塩基性のため歯髄の表層を一層壊死せしめるこ
とが多い。この強い塩基性は歯髄の表層のみ壊死
する場合と、歯髄組織の体積が小さく、かつ、生
活力が低下しているような場合には歯髄全体を壊
死させてしまうことが多い。 Since Hellman's (1928) research on pulp capping agents for exposed pulp, many people have been conducting research on better pulp capping agents. At present, pulp capping agents that are formed relatively easily and at a high rate are those containing calcium hydroxide as a main component, such as Life and Daical (trade names). In particular, when using only calcium hydroxide, dentine bridges are formed at a higher rate. however,
Although the ability to form dentine bridges is certainly high, calcium hydroxide preparations often cause further necrosis of the surface layer of the dental pulp due to their characteristic high basicity. This strong basicity often causes necrosis of the entire dental pulp in cases where only the surface layer of the dental pulp becomes necrotic, or in cases where the volume of the pulp tissue is small and the vitality is reduced.
〈発明が解決しようとする問題点〉
本発明は上記実情に鑑み発明したものであつ
て、毒性を有しないため細胞に刺激を与えず、か
つ、歯髄を壊死させることなく、しかも、人の歯
の成分であるカルシウム、りんの成分と同じ成分
からなる珊瑚を主成分とし、これに鎮痛作用を有
する水酸化カルシウムを混合し、滅菌蒸溜水によ
つて混練することにより、刺激性なく、かつ、被
蓋象牙質を作り、しかも、歯髄の壊死を招くよう
な虞のない理想的な歯科用覆髄剤を提供せんとす
るものである。<Problems to be solved by the invention> The present invention was invented in view of the above circumstances, and is non-toxic, does not stimulate cells, does not cause necrosis of the dental pulp, and is The main component is coral, which is the same as the calcium and phosphorus components, and is mixed with calcium hydroxide, which has an analgesic effect, and kneaded with sterile distilled water to create a non-irritating and It is an object of the present invention to provide an ideal dental pulp capping agent that creates dentin capping and does not cause necrosis of the dental pulp.
〈問題点を解決するための手段〉
本発明は焼成した珊瑚の粉末を80〜85重量％
と、水酸化カルシウムを15〜20重量％の配分率で
混合し、滅菌蒸溜水によつて混練したことを特徴
としたものである。<Means for solving the problems> The present invention uses 80 to 85% by weight of fired coral powder.
and calcium hydroxide at a distribution ratio of 15 to 20% by weight, and the mixture was kneaded with sterile distilled water.
〈作用〉
上記手段を用いることで、刺激性なく、かつ、
被蓋象牙質を作り、しかも、歯髄の壊死を招くこ
とのない歯科用覆髄剤を構成したものである。<Effect> By using the above means, it is non-irritating and
This is a dental pulp capping agent that creates capping dentin and does not cause pulp necrosis.
〈実施例〉
珪瑚の粉末を200〜300℃で30分間焼成し、該珊
瑚の粉末85重量％と、水酸化カルシウムを15重量
％の配分率で混合し、次に少量の滅菌蒸溜水によ
つて混練して歯科用覆髄剤を得る。<Example> Calcinate coral powder at 200 to 300°C for 30 minutes, mix 85% by weight of the coral powder and 15% by weight of calcium hydroxide, and then add to a small amount of sterilized distilled water. Then knead to obtain a dental pulp capping agent.
本発明品の覆髄剤を、第１に組織に対する刺激
為害性の有無を調べるため、ラツトの背部皮下に
包埋し、３〜６ケ月間検査した結果、刺激のない
ことが解つた。 The pulp capping agent of the present invention was firstly embedded subcutaneously in the backs of rats to determine whether it was irritating or harmful to tissues, and the test was conducted for 3 to 6 months, and it was found that there was no irritation.
第２に第１図に示すように、犬の歯１を用い、
これに麻酔下で生きている歯髄２の切断法、即
ち、バー３で生活歯髄切断を行ない、次に第２図
に示すように歯髄切断面２ａを、裏層器４を用い
て本発明品の覆髄剤５によりカバーし、さらに覆
髄剤５上にセメントの充填材６を充填し、ポスト
７によつてレジン歯８を接続し、１〜６ケ月間飼
育した。のち、光学顕微鏡で観察したところ、第
３図に示すように該覆髄剤３でカバーしてから１
〜２ケ月間経過した時より、歯髄切断面２ａ部
分、即ち、覆髄剤３と歯髄２の境界部分に被蓋象
牙質（デンテインブリツヂ）９の形成が始まつた
ことが認められた。 Second, as shown in FIG. 1, using canine tooth 1,
This is followed by cutting the living pulp 2 under anesthesia, that is, cutting the living pulp with a burr 3, and then, as shown in FIG. The pulp capping agent 5 was further filled with a cement filling material 6, a resin tooth 8 was connected with a post 7, and the teeth were raised for 1 to 6 months. Afterwards, when observed with an optical microscope, it was found that after covering with the pulp capping agent 3, as shown in FIG.
After ~2 months had passed, it was observed that dentine bridge 9 had begun to form at the pulp cut surface 2a, that is, at the boundary between the pulp capping agent 3 and the pulp 2. .
第３には、歯科矯正治療上、抜かなければなら
ない人の歯に対し第２の場合と同様に、麻酔下で
生活歯髄切断法を行ない、本発明品の覆髄剤でカ
バーし、１〜６ケ月間観察した。のち、光学顕微
鏡で観察したところ歯数の中で90％の高い割合で
被蓋象牙質が認められた。 Thirdly, as in the second case, vital pulp cutting is performed on a human tooth that needs to be extracted for orthodontic treatment under anesthesia, and the pulp is covered with the pulp capping agent of the present invention. It was observed for 6 months. Later, when the teeth were observed using an optical microscope, dentine was found in a high proportion of 90% of the teeth.
〈発明の効果〉
上述したように本発明は焼成した珊瑚の粉末を
80〜85重量％と、水酸化カルシウムを15〜20重量
％の配分率で混合し、滅菌蒸溜水によつて混練し
たことを特徴とする歯科用覆髄剤であつて、先
ず、珊瑚の粉末を焼成することは、珊瑚の粉末に
よりアレルギー作用を生ずるのを防止したもので
あり、また、滅菌蒸溜水によつて混練したこと
は、これまた、細菌による幣害をなくしたもので
ある。<Effects of the Invention> As mentioned above, the present invention uses fired coral powder.
A dental pulp capping agent characterized by mixing 80 to 85% by weight of calcium hydroxide and 15 to 20% by weight of calcium hydroxide and kneading with sterilized distilled water. The firing process prevents the coral powder from causing allergic reactions, and the kneading with sterile distilled water also eliminates bacterial damage.
しかして、本発明において主成分となる焼成し
た珊瑚の粉末は、毒性を有しないため細胞に刺激
を与えず、かつ、歯髄を壊死させることがなく、
しかも、珊瑚の成分であるカルシウム、リンによ
つて歯髄細胞が分化されて象牙質牙細胞を作り、
さらにこれが増殖されて被蓋象牙質を作つて歯髄
を保護したものである。即ち、本発明品の覆髄剤
は水酸化カルシウム製剤に比べて高率に被蓋象牙
質が形成されること及び組織に対する親和性を有
する。また、水酸化カルシウムによつて痛みを防
ぐことができる特長がある。 Therefore, the calcined coral powder, which is the main ingredient in the present invention, is non-toxic and does not stimulate cells and does not cause necrosis of the dental pulp.
Moreover, calcium and phosphorus, which are components of coral, cause dental pulp cells to differentiate and form dentin cells.
This is then multiplied to form capping dentin, which protects the dental pulp. That is, the pulp capping agent of the present invention forms capping dentin at a higher rate than calcium hydroxide preparations and has an affinity for tissues. Additionally, calcium hydroxide has the advantage of preventing pain.
第１図は犬の歯に生活歯髄切断を行なつた場合
の断面を示す説明図、第２図は歯髄切断面を本発
明品の覆髄剤でカバーした場合の断面を示す説明
図、第３図は覆髄剤と歯髄の境界部分に被蓋象牙
質が形成された状態を示す断面の説明図である。
Fig. 1 is an explanatory diagram showing a cross section when vital pulp is cut in a canine tooth; Fig. 2 is an explanatory diagram showing a cross section when the pulp cut surface is covered with the pulp capping agent of the present invention; FIG. 3 is an explanatory diagram of a cross section showing a state in which capping dentin is formed at the boundary between the pulp capping agent and the dental pulp.
Claims (1)
化カルシウムを15〜20重量％の配分率で混合し、
滅菌蒸溜水によつて混練したことを特徴とする歯
科用覆髄剤。1. Mix 80 to 85% by weight of calcined coral powder and 15 to 20% by weight of calcium hydroxide,
A dental pulp capping agent characterized by being kneaded with sterile distilled water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61148993A JPS635008A (en) | 1986-06-25 | 1986-06-25 | Dental pulp capping agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61148993A JPS635008A (en) | 1986-06-25 | 1986-06-25 | Dental pulp capping agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS635008A JPS635008A (en) | 1988-01-11 |
| JPH0427201B2 true JPH0427201B2 (en) | 1992-05-11 |
Family
ID=15465301
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61148993A Granted JPS635008A (en) | 1986-06-25 | 1986-06-25 | Dental pulp capping agent |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS635008A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202319337A (en) * | 2021-11-12 | 2023-05-16 | 仆派海洋生技股份有限公司 | Tricalcium phosphate porous material, and use and preparation method thereof having significantly better mechanical properties and bone repairing efficacy |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50124489A (en) * | 1974-02-25 | 1975-09-30 | ||
| JPS6130507A (en) * | 1984-07-20 | 1986-02-12 | Kyocera Corp | Curable paste agent for filling root canal |
-
1986
- 1986-06-25 JP JP61148993A patent/JPS635008A/en active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50124489A (en) * | 1974-02-25 | 1975-09-30 | ||
| JPS6130507A (en) * | 1984-07-20 | 1986-02-12 | Kyocera Corp | Curable paste agent for filling root canal |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS635008A (en) | 1988-01-11 |
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