JPH04210070A - Manufacture of mixing/injecting section - Google Patents
Manufacture of mixing/injecting sectionInfo
- Publication number
- JPH04210070A JPH04210070A JP2401289A JP40128990A JPH04210070A JP H04210070 A JPH04210070 A JP H04210070A JP 2401289 A JP2401289 A JP 2401289A JP 40128990 A JP40128990 A JP 40128990A JP H04210070 A JPH04210070 A JP H04210070A
- Authority
- JP
- Japan
- Prior art keywords
- synthetic resin
- connection member
- resin cap
- connecting member
- high frequency
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004519 manufacturing process Methods 0.000 title claims description 12
- 229920003002 synthetic resin Polymers 0.000 claims abstract description 53
- 239000000057 synthetic resin Substances 0.000 claims abstract description 53
- 239000007788 liquid Substances 0.000 claims abstract description 25
- 229920001971 elastomer Polymers 0.000 claims abstract description 24
- 239000005060 rubber Substances 0.000 claims abstract description 24
- 238000012546 transfer Methods 0.000 claims abstract description 20
- 238000003466 welding Methods 0.000 claims abstract description 20
- 238000000034 method Methods 0.000 claims abstract description 18
- 238000005304 joining Methods 0.000 claims abstract description 7
- 238000002347 injection Methods 0.000 claims description 36
- 239000007924 injection Substances 0.000 claims description 36
- 229920002457 flexible plastic Polymers 0.000 claims description 17
- 230000002093 peripheral effect Effects 0.000 claims description 8
- 229920003023 plastic Polymers 0.000 claims description 8
- 239000004033 plastic Substances 0.000 claims description 8
- BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 abstract description 7
- 238000000926 separation method Methods 0.000 abstract description 2
- 229920005989 resin Polymers 0.000 description 11
- 239000011347 resin Substances 0.000 description 11
- 239000000853 adhesive Substances 0.000 description 10
- 230000001070 adhesive effect Effects 0.000 description 10
- 239000000463 material Substances 0.000 description 7
- 210000001124 body fluid Anatomy 0.000 description 5
- 239000010839 body fluid Substances 0.000 description 5
- 239000005062 Polybutadiene Substances 0.000 description 4
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 4
- DQXBYHZEEUGOBF-UHFFFAOYSA-N but-3-enoic acid;ethene Chemical compound C=C.OC(=O)CC=C DQXBYHZEEUGOBF-UHFFFAOYSA-N 0.000 description 4
- 239000005038 ethylene vinyl acetate Substances 0.000 description 4
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 description 4
- 229920002857 polybutadiene Polymers 0.000 description 4
- -1 polyethylene Polymers 0.000 description 4
- 238000004113 cell culture Methods 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 229920000219 Ethylene vinyl alcohol Polymers 0.000 description 2
- 244000043261 Hevea brasiliensis Species 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 229920001328 Polyvinylidene chloride Polymers 0.000 description 2
- 239000004715 ethylene vinyl alcohol Substances 0.000 description 2
- RZXDTJIXPSCHCI-UHFFFAOYSA-N hexa-1,5-diene-2,5-diol Chemical compound OC(=C)CCC(O)=C RZXDTJIXPSCHCI-UHFFFAOYSA-N 0.000 description 2
- 238000001802 infusion Methods 0.000 description 2
- 229920003052 natural elastomer Polymers 0.000 description 2
- 229920001194 natural rubber Polymers 0.000 description 2
- 239000003960 organic solvent Substances 0.000 description 2
- 229920000728 polyester Polymers 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 239000005033 polyvinylidene chloride Substances 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 2
- 229920006257 Heat-shrinkable film Polymers 0.000 description 1
- 229920006311 Urethane elastomer Polymers 0.000 description 1
- 229920005549 butyl rubber Polymers 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 239000011810 insulating material Substances 0.000 description 1
- 229920003049 isoprene rubber Polymers 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 229920006255 plastic film Polymers 0.000 description 1
- 229920002050 silicone resin Polymers 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 229920003051 synthetic elastomer Polymers 0.000 description 1
- 239000005061 synthetic rubber Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/05—Particular design of joint configurations
- B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
- B29C66/11—Joint cross-sections comprising a single joint-segment, i.e. one of the parts to be joined comprising a single joint-segment in the joint cross-section
- B29C66/112—Single lapped joints
- B29C66/1122—Single lap to lap joints, i.e. overlap joints
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
- B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
- B29C65/04—Dielectric heating, e.g. high-frequency welding, i.e. radio frequency welding of plastic materials having dielectric properties, e.g. PVC
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/05—Particular design of joint configurations
- B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
- B29C66/13—Single flanged joints; Fin-type joints; Single hem joints; Edge joints; Interpenetrating fingered joints; Other specific particular designs of joint cross-sections not provided for in groups B29C66/11 - B29C66/12
- B29C66/131—Single flanged joints, i.e. one of the parts to be joined being rigid and flanged in the joint area
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
- B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
- B29C66/53—Joining single elements to tubular articles, hollow articles or bars
- B29C66/534—Joining single elements to open ends of tubular or hollow articles or to the ends of bars
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/80—General aspects of machine operations or constructions and parts thereof
- B29C66/81—General aspects of the pressing elements, i.e. the elements applying pressure on the parts to be joined in the area to be joined, e.g. the welding jaws or clamps
- B29C66/818—General aspects of the pressing elements, i.e. the elements applying pressure on the parts to be joined in the area to be joined, e.g. the welding jaws or clamps characterised by the cooling constructional aspects, or by the thermal or electrical insulating or conducting constructional aspects of the welding jaws or of the clamps ; comprising means for compensating for the thermal expansion of the welding jaws or of the clamps
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/80—General aspects of machine operations or constructions and parts thereof
- B29C66/83—General aspects of machine operations or constructions and parts thereof characterised by the movement of the joining or pressing tools
- B29C66/832—Reciprocating joining or pressing tools
- B29C66/8322—Joining or pressing tools reciprocating along one axis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
- B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
- B29C65/08—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using ultrasonic vibrations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/05—Particular design of joint configurations
- B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
- B29C66/12—Joint cross-sections combining only two joint-segments; Tongue and groove joints; Tenon and mortise joints; Stepped joint cross-sections
- B29C66/122—Joint cross-sections combining only two joint-segments, i.e. one of the parts to be joined comprising only two joint-segments in the joint cross-section
- B29C66/1222—Joint cross-sections combining only two joint-segments, i.e. one of the parts to be joined comprising only two joint-segments in the joint cross-section comprising at least a lapped joint-segment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/05—Particular design of joint configurations
- B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
- B29C66/12—Joint cross-sections combining only two joint-segments; Tongue and groove joints; Tenon and mortise joints; Stepped joint cross-sections
- B29C66/122—Joint cross-sections combining only two joint-segments, i.e. one of the parts to be joined comprising only two joint-segments in the joint cross-section
- B29C66/1224—Joint cross-sections combining only two joint-segments, i.e. one of the parts to be joined comprising only two joint-segments in the joint cross-section comprising at least a butt joint-segment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
- B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
- B29C66/53—Joining single elements to tubular articles, hollow articles or bars
- B29C66/532—Joining single elements to the wall of tubular articles, hollow articles or bars
- B29C66/5324—Joining single elements to the wall of tubular articles, hollow articles or bars said single elements being substantially annular, i.e. of finite length
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
- B29C66/71—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the composition of the plastics material of the parts to be joined
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Lining Or Joining Of Plastics Or The Like (AREA)
Abstract
Description
［０００１１ [00011
【産業上の利用分野］本発明は、医療用もしくは細胞培
養用可撓性プラスチック容器に、または体液処理用回路
を構成する液体移送チューブに設けられる混注部の製造
方法に関する。
［０００２］
【従来の技術】医療用や細胞培養用の可撓性プラスチッ
ク容器や、体液処理用回路を構成する液体移送チューブ
の途中には、混注ゴムを用いた混注部が構成されている
ことが多い。すなわち、可撓性プラスチック容器では、
筒状の口部に混注ゴムを圧入し、口部の開口端側から合
成樹脂製キャップを被着してなる混注部が構成されてお
り（実公平２−９８１０号）、液体移送チューブでは、
チューブの途中に筒状の接続部材を接続し、該接続部材
内に混注ゴムを圧入し、筒状部材の他方端側に合成樹脂
製キャップを被着することにより混注部が構成されてい
る（例えば実公平２−２３３１２号）。
［０００３］上記のような混注部は、シリンジの針先を
混注ゴムを貫通させ、シリンジにより内部の液体を取り
出すことを可能とするために、並びにプラスチック容器
または液体移送チューブ内の液体にシリンジより薬剤等
を添加することを可能とするために設けられている。と
ころで、上記混注部では、合成樹脂よりなる筒状接続部
材と混注ゴムとの間、並びに合成樹脂製キャップと接続
部材との間の液密性が保たれている必要がある。さもな
ければ、例えば輸液のようなプラスチック容器内の液体
が混注部から容器外に漏れ出したり、液体移送チューブ
を流れている体液等が外部に漏れ出すおそれがあるから
である。特に、液体移送チューブでは、送液ポンプの加
圧力等により、チューブ内の圧力が非常に高くなる場合
があり、従って合成樹脂製キャップは、筒状部材に強固
に接合されていることが要請される。
［０００４］従来、上記筒状接続部材と合成樹脂製キャ
ップの接合は、接着剤あるいは熱収縮シールにより行わ
れていた。接着剤による方法は、例えばテトラヒドロフ
ラン（ＴＨＦ）のような有機溶剤を接着剤として用いた
接合方法であり、他方、熱収縮シールは、加熱により収
縮するフィルムを合成樹脂製キャップの外側を囲むよう
に取り付け、熱収縮させて緊張させることにより合成樹
脂製キャップを接続部材の周囲に固着する方法である。
［０００５］また、実公平２−９８１０号では、筒状接
続部材としてのプラスチック製容器の口部と、合成樹脂
製キャップとの密着性を高めるために、筒状接続部材の
外周面と、合成樹脂製キャップの内周面とに、互いに嵌
合し合う環状の凹部及び凸部を形成した構造が開示され
ており、さらにヒートシールをも適用することにより両
者の密着性がより一層高められる旨記載されている。
［０００６］[Industrial Field of Application] The present invention relates to a method for manufacturing a co-injection unit provided in a flexible plastic container for medical use or cell culture, or in a liquid transfer tube constituting a body fluid processing circuit. [0002] [0002] [0002] A mixed injection section using mixed injection rubber is constructed in the middle of a flexible plastic container for medical use or cell culture, or a liquid transfer tube constituting a body fluid processing circuit. There are many. In other words, for flexible plastic containers,
The mixed injection section is constructed by press-fitting mixed injection rubber into a cylindrical mouth and covering it with a synthetic resin cap from the open end of the mouth (Refer to Utility Model Publication No. 2-9810).
The mixed injection part is constructed by connecting a cylindrical connecting member in the middle of the tube, press-fitting the mixed injection rubber into the connecting member, and covering the other end of the cylindrical member with a synthetic resin cap. For example, Jikkoi No. 2-23312). [0003] The co-injection part as described above is used to allow the needle tip of the syringe to penetrate the co-injection rubber and take out the liquid inside with the syringe, and also to allow the syringe to penetrate the liquid in the plastic container or liquid transfer tube. It is provided to enable the addition of drugs and the like. By the way, in the co-injection part, it is necessary to maintain liquid tightness between the cylindrical connection member made of synthetic resin and the co-injection rubber, and between the synthetic resin cap and the connection member. Otherwise, there is a risk that the liquid in the plastic container, such as an infusion, may leak out of the container from the mixed injection part, or the body fluid flowing through the liquid transfer tube may leak to the outside. In particular, in liquid transfer tubes, the pressure inside the tube may become extremely high due to the pressurizing force of the liquid transfer pump, etc. Therefore, the synthetic resin cap must be firmly bonded to the cylindrical member. Ru. [0004] Conventionally, the cylindrical connecting member and the synthetic resin cap have been joined using an adhesive or a heat-shrinkable seal. The adhesive method is a bonding method that uses an organic solvent such as tetrahydrofuran (THF) as an adhesive, while the heat shrink seal method uses a film that shrinks when heated to surround the outside of a synthetic resin cap. This is a method of fixing a synthetic resin cap around a connecting member by attaching it, heat-shrinking it, and tightening it. [0005] Furthermore, in Utility Model Publication No. 2-9810, in order to improve the adhesion between the opening of the plastic container as the cylindrical connecting member and the synthetic resin cap, the outer peripheral surface of the cylindrical connecting member and the synthetic resin cap are A structure is disclosed in which annular recesses and protrusions are formed on the inner circumferential surface of the resin cap, and the adhesion between the two is further improved by applying heat sealing. Are listed. [0006]
【発明が解決しようとする課題】従来の混注部における
筒状接続部材と合成樹脂製キャップの接合方法のうち、
接着剤を用いた方法では、接着剤の両者間の隙間への浸
透が十分でないためか、両者の接触面が全周に渡って接
着されていないことがあった。また、接着剤が筒状接続
部材や合成樹脂製キャップを構成しているプラスチック
表面や素材中に残留することが避けられないという問題
もあった。
［０００７］他方、熱収縮シールを用いた方法では、筒
状接続部材と合成樹脂製キャップを完全に一体化するこ
とが困難であり、熱収縮不良が生じがちであった。従っ
て、使用しているうちに合成樹脂製キャップが筒状の接
続部材から外れ、内容物が汚染されることがあった。さ
らに、実公平２−９８１０号に開示されているように、
筒状接続部材としての口部の外周面と、合成樹脂製キャ
ップの内周面とに、互いに嵌合し合う環状の凹部及び凸
部を設け、さらにヒートシールを行ったとしても、両者
の密着性は、なお十分なものではなかった。のみならず
、この先行技術の方法では、筒状接続部材の外周面及び
合成樹脂製キャップ内周面に、上記のような環状の凹凸
を正確に設ける必要があり、さらに該凹凸が正確に形成
されない場合には、逆に両者間の接合部における液密性
が損なわれるという問題もあった。
［０００８］よって、本発明の目的は、上述した先行技
術における種々の問題点を解消するものであり、筒状の
接続部材に対して合成樹脂製キャップが強固に接合され
ており、従って内部の液体の漏洩や合成樹脂製キャップ
の離脱が生じ難い構造を備えた混注部の製造方法を提供
することにある。
［０００９］[Problems to be Solved by the Invention] Among the conventional methods for joining a cylindrical connecting member and a synthetic resin cap in a mixed injection section,
In the method using an adhesive, the contact surface between the two may not be bonded all the way around, probably because the adhesive does not penetrate sufficiently into the gap between the two. Another problem is that the adhesive inevitably remains on the plastic surface or in the material that constitutes the cylindrical connecting member or the synthetic resin cap. [0007] On the other hand, in the method using a heat shrinkable seal, it is difficult to completely integrate the cylindrical connecting member and the synthetic resin cap, and poor heat shrinkage tends to occur. Therefore, during use, the synthetic resin cap may come off from the cylindrical connecting member and the contents may be contaminated. Furthermore, as disclosed in Utility Model No. 2-9810,
Even if annular recesses and protrusions that fit into each other are provided on the outer circumferential surface of the opening as a cylindrical connecting member and the inner circumferential surface of the synthetic resin cap, and even if heat sealing is performed, the two will not come into close contact. Sex was still not enough. In addition, in the method of this prior art, it is necessary to accurately provide the above-mentioned annular irregularities on the outer circumferential surface of the cylindrical connecting member and the inner circumferential surface of the synthetic resin cap, and furthermore, it is necessary to accurately form the annular irregularities. If this is not done, there is a problem in that the liquid tightness at the joint between the two is impaired. [0008] Therefore, an object of the present invention is to solve the various problems in the prior art described above, and the synthetic resin cap is firmly joined to the cylindrical connecting member, so that the internal It is an object of the present invention to provide a method for manufacturing a co-injection part having a structure that prevents liquid leakage and separation of a synthetic resin cap. [0009]
【課題を解決するための手段】本発明は、可撓性プラス
チック容器に、または液体移送用チューブの途中に設け
られる混注部の製造方法であって、前記プラスチック容
器の容器本体に、または液体移送チューブの途中に一方
端が接続される筒状の接続部材を用意し、前記接続部材
の他方端側より該接続部材に混注ゴムを圧入し、前記接
続部材の他方端側において合成樹脂製キャップを被せ、
前記接続部材の外周面と合成樹脂製キャップの内面とを
高周波溶着または超音波溶着により接合することを特徴
とするものである。
［００１０１以下、本発明の構成を詳細に説明する。本
発明において筒状の接続部材としては、可撓製プラスチ
ック容器の容器本体もしくは液体移送チューブ及び合成
樹脂製キャップと接合可能であれば、適宜の材料からな
るものを用いることができる。このような材料としては
、例えば、軟質塩化ビニル樹脂、エチレン酢酸ビニル樹
脂、ポリエチレン、ポリプロピレン、ポリブタジェン、
フッ素化樹脂、ポリ塩化ビニリデン、エチレンビニルア
ルコールまたはポリエステル等からなるものが挙げられ
る。もっとも、好ましくは、接続される可撓製プラスチ
ック容器の容器本体、液体移送チューブまたは合成樹脂
製キャップと同一材料が用いられる。また、筒状接続部
材の形状については、用途によって適宜変更し得るが、
混注ゴムを圧入するための他方端側の開口部以外に、他
の開口部を有する形状、例えばＹ型またはＹ型のような
形状とされていてもよい。
［００１１］上記接続部材に圧入される混注ゴムとして
は、天然ゴム、またはイソプレンゴム、ブチルゴム、ブ
タジェンゴム、シリコンゴムもしくはウレタンゴム等の
合成ゴムからなるものを適宜用いることができる。また
、混注ゴムの形状については、接続部材に圧入された状
態で液密状態を維持することができる限り、その断面形
状は任意である。
［００１２］合成樹脂製キャップとしては、天面と、筒
状接続部材に被せられた状態で天面の周囲から筒状接続
部材の外周面に延びる環状側壁とを有する形状のものが
用いられるが、通常は、天面中央に開口が形成されてい
る。この開口は、シリンジの針を混注ゴムに貫通させる
作業を妨げないために設けられているものである。もっ
とも、合成樹脂製キャップの天面が非常に薄い場合には
、上記開口は設けられずともよい。また、合成樹脂製キ
ャップを構成する材料としては、特に限定されないが、
好ましくは、筒状の接続部材と同一材料からなるものが
用いられる。
［００１３］本発明では、まず、可撓性プラスチック容
器の容器本体に、または液体移送チューブの途中に一方
端が接続される筒状接続部材を用意する。この筒状接続
部材の用意は、可撓性プラスチック容器の容器本体に。
または液体移送チューブの途中に接続された状態で用意
されてもよいが、通常は、独立した部品として筒状接続
部材が用意される。
［００１４］次に、上記接続部材の他方端側から、混注
ゴムを圧入する。この圧入は、通常は、混注ゴムの外方
端が筒状接続部材の他方端からはみ出た状態まで行われ
るが、場合によっては、混注ゴムは筒状接続部材の他方
端よりも内側に陥没する状態まで圧入されてもよい。次
に、筒状接続部材の他方端側において、合成樹脂製キャ
ップを被せる。そして、接続部材の外周面と合成樹脂製
キャップの内周面とを、高周波溶着または超音波溶着に
より接合する。高周波溶着は、合成樹脂製キャップの内
面を筒状接続部材の外周面に当接させた状態で、合成樹
脂製キャップに高周波電圧を印加することにより行われ
る。同様に、超音波溶着は、合成樹脂製キャップの内周
面を筒状接続部材の外周面に当接させた状態で、合成樹
脂製キャップに超音波を加えて溶着し、両者を接合する
。
［００１５１本発明により得られる混注部が設けられる
可撓性プラスチック容器としては、輸液容器や細胞培養
用容器等の種々の医療用あるいは生化学用容器が挙げら
れる。このような可撓性プラスチック容器としては、軟
質塩化ビニル樹脂、エチレン酢酸ビニル樹脂、ポリエチ
レン、ポリプロピレン、ポリブタジェン、フッ素化樹脂
、ポリ塩化ビニリデン、エチレンビニルアルコールまた
はポリエステル等からなるものが挙げられる。また、可
撓性プラスチック容器の場合には、容器本体の一部に設
けられた口部が、上記筒状接続部材を兼ねることになる
。従って、上記プラスチック容器の材料としては、好ま
しくは、軟質塩化ビニル樹脂やエチレン酢酸ビニル樹脂
等が用いられる。なお、上記のような可撓性プラスチッ
ク容器には、本発明の製造方法により得られる混注部以
外に、他の１以上の接続部材が取り付けられてもよい。
［００１６１本発明の製造方法により得られる混注部が
設けられる液体移送チューブとしては、体外循環回路を
構成するための液体移送チューブや、分析装置の液体移
送チューブ等が挙げられ、通常、軟質塩化ビニル樹脂、
エチレン酢酸ビニル樹脂、シリコン樹脂またはポリブタ
ジェン等により構成されている。
［００１７］[Means for Solving the Problems] The present invention provides a method for manufacturing a co-injection section provided in a flexible plastic container or in the middle of a liquid transfer tube, which A cylindrical connecting member with one end connected to the middle of the tube is prepared, mixed injection rubber is press-fitted into the connecting member from the other end of the connecting member, and a synthetic resin cap is attached to the other end of the connecting member. Cover,
It is characterized in that the outer peripheral surface of the connecting member and the inner surface of the synthetic resin cap are joined by high frequency welding or ultrasonic welding. [00101 Below, the configuration of the present invention will be explained in detail. In the present invention, the cylindrical connecting member may be made of any suitable material as long as it can be joined to the container body of the flexible plastic container, the liquid transfer tube, and the synthetic resin cap. Examples of such materials include soft vinyl chloride resin, ethylene vinyl acetate resin, polyethylene, polypropylene, polybutadiene,
Examples include those made of fluorinated resin, polyvinylidene chloride, ethylene vinyl alcohol, or polyester. However, preferably, the same material is used as the container body, liquid transfer tube, or synthetic resin cap of the flexible plastic container to be connected. Furthermore, the shape of the cylindrical connecting member can be changed as appropriate depending on the application, but
In addition to the opening at the other end for press-fitting the co-injected rubber, the opening may have another opening, for example, a Y-shape or a Y-shape. [0011] As the co-injected rubber press-fitted into the connection member, natural rubber or synthetic rubber such as isoprene rubber, butyl rubber, butadiene rubber, silicone rubber, or urethane rubber can be used as appropriate. Furthermore, the cross-sectional shape of the co-injected rubber can be arbitrary as long as it can maintain a liquid-tight state when press-fitted into the connecting member. [0012] As a synthetic resin cap, one having a shape having a top surface and an annular side wall that extends from the periphery of the top surface to the outer peripheral surface of the cylindrical connection member while being placed over the cylindrical connection member is used. , usually an opening is formed in the center of the top surface. This opening is provided so as not to interfere with the operation of penetrating the co-injected rubber with the needle of the syringe. However, if the top surface of the synthetic resin cap is very thin, the opening may not be provided. In addition, the material constituting the synthetic resin cap is not particularly limited, but
Preferably, one made of the same material as the cylindrical connecting member is used. [0013] In the present invention, first, a cylindrical connecting member is prepared, one end of which is connected to the container body of a flexible plastic container or to the middle of a liquid transfer tube. Prepare this cylindrical connection member on the container body of the flexible plastic container. Alternatively, the cylindrical connecting member may be prepared as being connected in the middle of the liquid transfer tube, but usually, the cylindrical connecting member is prepared as an independent component. [0014] Next, co-injected rubber is press-fitted from the other end of the connecting member. This press-fitting is normally performed until the outer end of the co-injected rubber protrudes from the other end of the cylindrical connecting member, but in some cases, the co-injected rubber recesses inward from the other end of the cylindrical connecting member. It may be press-fitted to the state. Next, a synthetic resin cap is placed on the other end of the cylindrical connection member. Then, the outer peripheral surface of the connecting member and the inner peripheral surface of the synthetic resin cap are joined by high frequency welding or ultrasonic welding. High frequency welding is performed by applying a high frequency voltage to the synthetic resin cap while the inner surface of the synthetic resin cap is in contact with the outer peripheral surface of the cylindrical connection member. Similarly, in ultrasonic welding, ultrasonic waves are applied to the synthetic resin cap while the inner circumferential surface of the synthetic resin cap is in contact with the outer circumferential surface of the cylindrical connecting member, thereby joining the two. [00151] Examples of the flexible plastic container provided with the co-injection part obtained by the present invention include various medical or biochemical containers such as infusion containers and cell culture containers. Examples of such flexible plastic containers include those made of soft vinyl chloride resin, ethylene vinyl acetate resin, polyethylene, polypropylene, polybutadiene, fluorinated resin, polyvinylidene chloride, ethylene vinyl alcohol, or polyester. Furthermore, in the case of a flexible plastic container, the opening provided in a part of the container body also serves as the cylindrical connecting member. Therefore, as the material for the plastic container, soft vinyl chloride resin, ethylene vinyl acetate resin, or the like is preferably used. Note that, in addition to the mixed injection part obtained by the manufacturing method of the present invention, one or more other connecting members may be attached to the flexible plastic container as described above. [00161 The liquid transfer tube provided with the co-injection part obtained by the manufacturing method of the present invention includes a liquid transfer tube for configuring an extracorporeal circulation circuit, a liquid transfer tube for an analyzer, etc., and is usually made of soft vinyl chloride. resin,
It is made of ethylene vinyl acetate resin, silicone resin, polybutadiene, etc. [0017]
【作用】本発明の混注部の製造方法では、高周波溶着ま
たは超音波溶着により、合成樹脂製キャップが筒状接続
部材に接合される。高周波溶着や超音波溶着は、接合部
材を高周波電流及び超音波により内部加熱するものであ
るため、合成樹脂製キャップと筒状接続部材との接合強
度は効果的に高められる。
［００１８］[Operation] In the method of manufacturing a co-injection part of the present invention, a synthetic resin cap is joined to a cylindrical connecting member by high frequency welding or ultrasonic welding. Since high frequency welding and ultrasonic welding internally heat the joining member using high frequency current and ultrasonic waves, the joining strength between the synthetic resin cap and the cylindrical connecting member can be effectively increased. [0018]
【実施例の説明】図１は、本発明の一実施例の混注部の
製造方法を説明するための断面図である。本実施例では
、先ず軟質塩化ビニルよりなる円筒状の接続部材１を用
意する。接続部材１の開口端のうち、切欠により図示さ
れていない側の開口端は、液体移送チューブ（図示せず
）に接続されるように構成されている。
［００１９１次に、上記接続部材１の他方の開口端１ａ
側から、混注ゴム２を圧入する。混注ゴム２は、天然ゴ
ムからなり、その外径が、接続部材１の内径よりも大き
くされており、従って、図示のように接続部材１に圧入
された状態で、接続部材１の内周面と混注ゴム２の外周
面との間の液密性が保たれている。次に、混注ゴム２が
接続部材１に圧入された状態で、軟質塩化ビニルよりな
る合成樹脂製キャップ３を被せる。合成樹脂製キャップ
３は、天面部３ａと、天面部３ａの周囲から接続部材１
側に延びる環状側壁３ｂとを有する。環状側壁３ｂの内
径は、筒状の接続部材１の外径とほぼ同等にされており
、従って合成樹脂製キャップ３を筒状接続部材１に被せ
た状態で、環状側壁３ｂの内周面が筒状接続部材１の外
周面に接触されている。なお、天面部３ａの中央には開
口３ｃが形成されている。
［００２０１本実施例では、合成樹脂製キャップ３を接
続部材１に被せた状態で、図示のように、高周波溶着装
置４内に挿入する。高周波溶着装置４は、絶縁部材５゜
６を、それぞれ、電極７，８及び９，１０で挟持した構
造を有する。電極７，９は、図１の矢印Ａ方向から見た
ときに半円形状を有する当接面７ａ、９ａを有し、該当
接面７ａ、９ａが組み合わさって、合成樹脂製キャップ
３の外周面の全周に渡って当接されるように構成されて
いる。同様に、絶縁部材５，６の当接面５ａ、６ａ及び
電極８．１０の当接面８ａ、１０ａも同様の形状に構成
されている。高周波溶着にあたっては、電極９，１０間
に、高周波電源１１を接続し、高周波電圧を印加する。
この場合、電極７，８は、電極９，１０と図示しない位
置で接触されているため、電極７，８間にも同様に高周
波電圧が印加される。
［００２１１出力３ＫＷの高周波電源１１を用い、周波
数４０ＭＨｚの高周波電圧を４秒間印加したところ、絶
縁部材５，６の当接面５ａ、６ａに接触している領域に
おいて、合成樹脂製キャップ３と筒状の接続部材１とが
全周に渡って溶着し、接合された。このようにして得ら
れた混注部を図２に示す。図２おいて、混注部１２内に
おいて矢印Ｂで示す部分が溶着部分である。なお、上記
のようにして高周波溶着された接続部材１と合成樹脂製
キャップ３との間の接合部分は、従来の接着剤や熱収縮
フィルムを利用した接合方法に比べて、優れた接合強度
を示すことが確かめれた。
［００２２］上記実施例で得られた混注部１２は、体液
移送チューブに接続されるものであるが、本発明は、図
３に示すように、可撓性プラスチック容器の一部に混注
部を設ける場合にも適用することができる。図３におい
て、１３は可撓性プラスチック容器を示し、容器本体１
４は、２枚のプラスチックフィルムを、破線Ｃの外側の
領域でヒートシールすることにより構成されている。そ
して、該容器本体１４に、筒状の接続部材としての口部
１５が接続されている。口部１５には、図２に示した混
注部１２と同様の構造を有する混注部１６が、上記実施
例と同様の方法により形成されている。このように、本
発明の混注部の製造方法は、体液移送用チューブに接続
される混注部だけでなく、可撓性プラスチック容器の一
部である凹部を利用して混注部を構成する場合にも適用
することができる。
［００２３］DESCRIPTION OF THE EMBODIMENTS FIG. 1 is a sectional view for explaining a method of manufacturing a co-injection part according to an embodiment of the present invention. In this embodiment, first, a cylindrical connecting member 1 made of soft vinyl chloride is prepared. Among the open ends of the connecting member 1, the open end on the side not shown by the notch is configured to be connected to a liquid transfer tube (not shown). [00191 Next, the other open end 1a of the connecting member 1
Press-fit the co-injected rubber 2 from the side. The co-injected rubber 2 is made of natural rubber, and its outer diameter is larger than the inner diameter of the connecting member 1. Therefore, when it is press-fitted into the connecting member 1 as shown in the figure, the inner circumferential surface of the connecting member 1 Liquid-tightness between the rubber and the outer circumferential surface of the co-injected rubber 2 is maintained. Next, with the mixed injection rubber 2 press-fitted into the connecting member 1, a synthetic resin cap 3 made of soft vinyl chloride is placed on the connecting member 1. The synthetic resin cap 3 has a top surface portion 3a and a connection member 1 from around the top surface portion 3a.
It has an annular side wall 3b extending to the side. The inner diameter of the annular side wall 3b is approximately the same as the outer diameter of the cylindrical connecting member 1. Therefore, when the synthetic resin cap 3 is placed on the cylindrical connecting member 1, the inner circumferential surface of the annular side wall 3b is It is in contact with the outer peripheral surface of the cylindrical connecting member 1. Note that an opening 3c is formed in the center of the top surface portion 3a. [00201 In this embodiment, the connecting member 1 is covered with the synthetic resin cap 3 and inserted into the high frequency welding device 4 as shown in the figure. The high frequency welding device 4 has a structure in which an insulating member 5.6 is sandwiched between electrodes 7, 8 and 9, 10, respectively. The electrodes 7 and 9 have contact surfaces 7a and 9a that have a semicircular shape when viewed from the direction of arrow A in FIG. It is configured to be in contact with the entire circumference of the surface. Similarly, the contact surfaces 5a, 6a of the insulating members 5, 6 and the contact surfaces 8a, 10a of the electrodes 8.10 are configured in a similar shape. For high frequency welding, a high frequency power source 11 is connected between the electrodes 9 and 10, and a high frequency voltage is applied. In this case, since the electrodes 7 and 8 are in contact with the electrodes 9 and 10 at positions not shown, a high frequency voltage is similarly applied between the electrodes 7 and 8. [00211 When a high frequency voltage with a frequency of 40 MHz was applied for 4 seconds using the high frequency power supply 11 with an output of 3 KW, the synthetic resin cap 3 and the cylinder were damaged in the areas in contact with the contact surfaces 5a and 6a of the insulating members 5 and 6. The shaped connecting member 1 was welded and joined over the entire circumference. The co-injection part thus obtained is shown in FIG. In FIG. 2, the part indicated by arrow B in the co-injection part 12 is the welded part. The joint between the connecting member 1 and the synthetic resin cap 3, which is high-frequency welded as described above, has superior joint strength compared to conventional joining methods using adhesives or heat-shrinkable films. It was confirmed that this was shown. [0022] The mixed injection part 12 obtained in the above embodiment is connected to the body fluid transfer tube, but the present invention, as shown in FIG. 3, includes a mixed injection part in a part of the flexible plastic container. It can also be applied when provided. In FIG. 3, 13 indicates a flexible plastic container, and the container body 1
4 is constructed by heat-sealing two plastic films in the area outside the broken line C. A mouth portion 15 serving as a cylindrical connecting member is connected to the container body 14 . A co-injection part 16 having the same structure as the co-injection part 12 shown in FIG. 2 is formed in the mouth part 15 by the same method as in the above embodiment. As described above, the method for manufacturing a mixed injection section of the present invention is applicable not only to the mixed injection section connected to the body fluid transfer tube, but also when the mixed injection section is configured using a recess that is a part of a flexible plastic container. can also be applied. [0023]
【発明の効果】本発明では、合成樹脂製キャップと筒状
の接続部材とが高周波溶着または超音波溶着により接合
されるため、合成樹脂製キャップと接続部材との間の接
合強度を効果的に高めることができる。また、接着剤を
用いた接合方法では、接着剤のプラスチック表面もしく
はプラスチック内部への残留が問題となっていたが、本
発明では接着剤を使用しないため、このような問題もな
く、また作業者が有機溶剤雰囲気中で作業する必要がな
く、さらに組み立て工程の自動化も容易に図り得る。
［００２４］また、本発明では、筒状接続部材や合成樹
脂製キャップに環状の嵌合凹部及び凸部を形成する必要
がないため、環状の凹部及び凸部を設けた場合のように
各部材を高精度に成形せずとも、接続部材と合成樹脂製
キャップを確実に接合することができる。
［００２５］[Effects of the Invention] In the present invention, since the synthetic resin cap and the cylindrical connecting member are joined by high frequency welding or ultrasonic welding, the bonding strength between the synthetic resin cap and the connecting member can be effectively increased. can be increased. In addition, with bonding methods using adhesives, there was a problem with the adhesive remaining on the plastic surface or inside the plastic, but since the present invention does not use adhesives, there is no such problem. There is no need to work in an organic solvent atmosphere, and the assembly process can be easily automated. [0024] Furthermore, in the present invention, there is no need to form annular fitting recesses and protrusions on the cylindrical connecting member and the synthetic resin cap, so each member The connecting member and the synthetic resin cap can be reliably joined without being molded with high precision. [0025]
［００２６］ [0026]
【図１】本発明の一実施例の製造方法を説明するための
部分切欠断面図。
［００２７］FIG. 1 is a partially cutaway sectional view for explaining a manufacturing method according to an embodiment of the present invention. [0027]
【図２】本発明の一実施例で得られた混注部を示す縦断
面図。
［００２８］FIG. 2 is a longitudinal sectional view showing a co-injection part obtained in an example of the present invention. [0028]
【図３】混注部が設けられたプラスチック製可撓性容器
を示す部分切欠正面断面図。
［００２９］FIG. 3 is a partially cutaway front sectional view showing a flexible plastic container provided with a mixed injection section. [0029]
１ 筒状の接続部材 ２ 混注ゴム ３ 合成樹脂製キャップ ４ 高周波溶着装置 ５．６ 絶縁部材 ７〜１０ 電極 １１ 高周波電源 1. Cylindrical connecting member 2 Mixed injection rubber 3. Synthetic resin cap 4 High frequency welding equipment 5.6 Insulating material 7-10 Electrode 11 High frequency power supply
【図１】[Figure 1]
Claims (1)
送チューブの途中に設けられる混注部の製造方法であっ
て、前記プラスチック容器の容器本体に、または前記液
体移送チューブの途中に一方端が接続される合成樹脂よ
りなる筒状接続部材を用意し、前記接続部材の他方端側
より該接続部材に混注ゴムを圧入し、前記接続部材の他
方端側に合成樹脂製キャップを被せ、前記接続部材の外
周面と合成樹脂製キャップの内面とを、高周波溶着また
は超音波溶着により接合することを特徴とする、混注部
の製造方法。1. A method for manufacturing a co-injection part provided in a flexible plastic container or in the middle of a liquid transfer tube, wherein one end is connected to the container body of the plastic container or in the middle of the liquid transfer tube. A cylindrical connecting member made of a synthetic resin is prepared, a co-injected rubber is press-fitted into the connecting member from the other end of the connecting member, a synthetic resin cap is placed on the other end of the connecting member, and the connecting member is A method for manufacturing a mixed injection part, characterized by joining the outer peripheral surface of the synthetic resin cap to the inner surface of the synthetic resin cap by high-frequency welding or ultrasonic welding.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2401289A JPH04210070A (en) | 1990-12-11 | 1990-12-11 | Manufacture of mixing/injecting section |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2401289A JPH04210070A (en) | 1990-12-11 | 1990-12-11 | Manufacture of mixing/injecting section |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH04210070A true JPH04210070A (en) | 1992-07-31 |
Family
ID=18511131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2401289A Pending JPH04210070A (en) | 1990-12-11 | 1990-12-11 | Manufacture of mixing/injecting section |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH04210070A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017035618A (en) * | 2013-03-15 | 2017-02-16 | ベクトン ディキンソン アンド カンパニー リミテッド | Connection system for medical device component |
-
1990
- 1990-12-11 JP JP2401289A patent/JPH04210070A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017035618A (en) * | 2013-03-15 | 2017-02-16 | ベクトン ディキンソン アンド カンパニー リミテッド | Connection system for medical device component |
| US10925807B2 (en) | 2013-03-15 | 2021-02-23 | Becton Dickinson and Company Ltd. | Connection system for medical device components |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA1058576A (en) | Attaching means and method for attaching flexible tubing to a plastic container | |
| JP3293122B2 (en) | Prefilled syringe | |
| US4854737A (en) | Bags for containing liquids | |
| JP2001522280A (en) | Sterile connector | |
| JP2004527408A (en) | Closure stopper for chemical bottles and method of making closure stopper | |
| JPH02192929A (en) | Bonding method for resin tube | |
| US4181549A (en) | Solvent-bonded joint and method of making the same | |
| AU771466B2 (en) | Membrane port for a container | |
| US3795558A (en) | Method of ultrasonic sealing hollow members | |
| JPH04210070A (en) | Manufacture of mixing/injecting section | |
| JP2001278320A (en) | Cap and its manufacturing method, and drug container using the cap | |
| JPH0720044Y2 (en) | Sealing structure of plastic container mouth | |
| JP6348125B2 (en) | cap | |
| JPH0840452A (en) | Drip container | |
| JP2599011B2 (en) | connector | |
| KR200377653Y1 (en) | Tubeless infusion tip | |
| WO2024103427A1 (en) | Integral inner film-coated connector and infusion bag | |
| CN1204573A (en) | Method for fixing medical tube to adapter of plastic | |
| JPH054835Y2 (en) | ||
| JPH06110Y2 (en) | Infusion plastic container | |
| JPH02255147A (en) | Plastic container for infusion | |
| KR810001445B1 (en) | Solvent bonded joint and method of making the same | |
| JPH1033635A (en) | Medical needle and medicine dissolution kit | |
| JP2005119739A (en) | Cap for medical plastic container | |
| JPH0736521Y2 (en) | Water bag for water bed |