JPH04197363A - Manufacture of catheter - Google Patents
Manufacture of catheterInfo
- Publication number
- JPH04197363A JPH04197363A JP2332030A JP33203090A JPH04197363A JP H04197363 A JPH04197363 A JP H04197363A JP 2332030 A JP2332030 A JP 2332030A JP 33203090 A JP33203090 A JP 33203090A JP H04197363 A JPH04197363 A JP H04197363A
- Authority
- JP
- Japan
- Prior art keywords
- catheter
- catheter body
- semihardened
- hardened
- metal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004519 manufacturing process Methods 0.000 title claims description 6
- 239000002184 metal Substances 0.000 claims abstract description 28
- 229910052751 metal Inorganic materials 0.000 claims abstract description 28
- 230000001954 sterilising effect Effects 0.000 claims abstract description 11
- 239000004033 plastic Substances 0.000 claims abstract description 6
- 229920003023 plastic Polymers 0.000 claims abstract description 6
- 239000002344 surface layer Substances 0.000 claims abstract description 5
- 238000007772 electroless plating Methods 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 9
- 230000000844 anti-bacterial effect Effects 0.000 claims description 8
- 208000015181 infectious disease Diseases 0.000 abstract description 8
- 238000007747 plating Methods 0.000 abstract description 8
- 229920005989 resin Polymers 0.000 abstract description 7
- 239000011347 resin Substances 0.000 abstract description 7
- 208000002193 Pain Diseases 0.000 abstract description 4
- 230000036407 pain Effects 0.000 abstract description 4
- 230000000873 masking effect Effects 0.000 abstract description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 2
- 238000010438 heat treatment Methods 0.000 abstract description 2
- 238000004299 exfoliation Methods 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 239000010949 copper Substances 0.000 description 10
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 9
- 229910052802 copper Inorganic materials 0.000 description 7
- PXHVJJICTQNCMI-UHFFFAOYSA-N nickel Substances [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 6
- 239000012530 fluid Substances 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 239000011248 coating agent Substances 0.000 description 4
- 238000000576 coating method Methods 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 239000010410 layer Substances 0.000 description 3
- 238000000465 moulding Methods 0.000 description 3
- 210000003708 urethra Anatomy 0.000 description 3
- 239000004809 Teflon Substances 0.000 description 2
- 229920006362 Teflon® Polymers 0.000 description 2
- 239000012190 activator Substances 0.000 description 2
- 239000003513 alkali Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229910021645 metal ion Inorganic materials 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- 229910052759 nickel Inorganic materials 0.000 description 2
- 238000004381 surface treatment Methods 0.000 description 2
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 206010046543 Urinary incontinence Diseases 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 201000003146 cystitis Diseases 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000005053 encephalomalacia Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- -1 ethanol Chemical compound 0.000 description 1
- 210000004392 genitalia Anatomy 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 231100000516 lung damage Toxicity 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 229920002050 silicone resin Polymers 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
Description
【発明の詳細な説明】
〔産業上の利用分野〕
本発明は体腔内に溜まった液体を排出したり、逆に液体
を体腔内に注入したりする医療用のカテーテル本体、特
に、尿道を経て膀胱に挿入する尿管カテーテル本体の壁
面に殺菌作用或いは滅菌作用を有する金属の膜を形成す
るカテーテルの製造方法に関するものである。[Detailed Description of the Invention] [Field of Industrial Application] The present invention relates to a medical catheter body for draining fluid accumulated in a body cavity or conversely injecting a fluid into a body cavity, particularly for a catheter body for discharging fluid accumulated in a body cavity or injecting a fluid into a body cavity through the urethra. The present invention relates to a method for manufacturing a catheter in which a metal film having a bactericidal or sterilizing effect is formed on the wall surface of a ureteral catheter body inserted into the bladder.
脳を髄疾患、例えば脳溢血、脳軟化症或いはを肺損傷等
では、しばしば排尿困難、尿失禁等の症状を伴うため、
尿管カテーテルを膀胱に挿入し、留置して排尿を行わせ
ている。また、手術後の患者には排尿の補助だけでなく
体腔内に溜まった液体や膿等を排出するために各種のカ
テーテルが使用され、これらのカテーテルはその必要性
から体腔内に留置して使用されることが多い。Diseases that affect the brain, such as cerebral hemorrhage, encephalomalacia, or lung damage, are often accompanied by symptoms such as difficulty urinating and urinary incontinence.
A ureteral catheter is inserted into the bladder and left in place to allow urination. In addition, various catheters are used for patients after surgery, not only to assist with urination, but also to drain fluids and pus accumulated in the body cavity. It is often done.
カテーテルを体腔内に留置したときに問題となるのが細
菌による感染症である。特に尿管カテーテルでは比較的
長時間尿道に留置しておくため、カテーテルを通じて肛
門や性器等に４１着している細菌がしばしば膀胱内に侵
入して膀胱炎を誘発させる原因をつくっている。特に、
女性の場合には男性と比較して尿道が太く、かつ短くて
直線的であるため、この細菌による感染が非常に多い。Bacterial infection is a problem when a catheter is placed in a body cavity. In particular, since ureteral catheters are left in the urethra for a relatively long period of time, bacteria that are present in the anus, genitals, etc., often enter the bladder through the catheter, causing cystitis. especially,
In women, the urethra is thicker, shorter, and straighter than in men, so infections caused by this bacteria are much more common in women.
この細菌の膀胱内侵入を防止するために従来はカテーテ
ルの管状体に殺菌作用或いは滅菌作用のある金属製リン
グまたはコイルを被着させたりする提案がなされている
（特公昭５４−１４８７６号参照）。In order to prevent these bacteria from entering the bladder, a proposal has been made to cover the tubular body of the catheter with a metal ring or coil that has a bactericidal or sterilizing effect (see Japanese Patent Publication No. 14876/1983). .
しかしながら、前記の金属リングやコイルを被着する方
法では金属リング等が太いため、カテーテルの管状体部
分の太さが太くなって患者への挿入に際し苦痛を増加さ
せることとなり、加えてカテーテルの管状体部分の所定
位置に金属リング等を固定しておくことが非常に困難で
あった。However, in the above-mentioned method of attaching a metal ring or coil, the metal ring, etc. is thick, so the tubular part of the catheter becomes thicker, which increases the pain when inserting it into the patient. It has been very difficult to keep metal rings etc. fixed at predetermined positions on the body part.
本発明は上記のような従来のカテーテルの問題点を解消
し、患者に苦痛を与えることなく、しかも感染症予防の
効果が長期間保持されるカテーテルを極めて安価に提供
することにある。The present invention solves the problems of conventional catheters as described above, and provides an extremely inexpensive catheter that does not cause pain to patients and maintains its effectiveness in preventing infections for a long period of time.
前記目的を達成するために、本発明は、ゴムまたはプラ
スチックでカテーテル本体を成型し、少なくとも人体の
体腔内に挿入される部分の表面層を半硬化の状態とし、
該半硬化の表面層に無電解メッキ処理を施して滅菌作用
あるいは殺菌作用を有する金属皮膜を形成し、次いで、
半硬化部分を所望の硬度に硬化することを特徴とするカ
テーテルの製造方法に関するものである。In order to achieve the above object, the present invention molds the catheter body from rubber or plastic, and makes the surface layer of at least the part inserted into the body cavity of the human body semi-hardened,
The semi-hardened surface layer is subjected to electroless plating to form a metal film having a sterilizing or bactericidal effect, and then
The present invention relates to a method for manufacturing a catheter, characterized in that a semi-hardened portion is hardened to a desired hardness.
本発明はカテーテルの管状体の少なくとも人体に挿入さ
れる部分の表面に無電解メッキ処理により殺菌作用或い
は滅菌作用を有する例えば銅、金、銀のような金属薄膜
を設けることで、金属の層を極めて薄く被着でき、従っ
てカテーテル管状体部分の太さが太くなるようなことが
ない（管内壁に被着した場合でも管の内径を狭めること
もない）。The present invention provides a thin layer of metal, such as copper, gold, or silver, which has a bactericidal or sterilizing effect by electroless plating on the surface of at least the portion of the tubular body of the catheter that is inserted into the human body. It can be applied extremely thinly, so the thickness of the catheter tubular body portion will not increase (even if it adheres to the inner wall of the tube, it will not narrow the inner diameter of the tube).
更に、無電解メッキ処理は、ゴムまたはプラスチックで
カテーテル本体を成型し、少なくとも金属皮膜を形成す
る部分を半硬化の状態で無電解メッキ処理を施し、次い
で該金属皮膜被着部を硬化させるので、メッキされる金
属が樹脂内に食い込め、容易に脱落することがなく、長
期間にわたって金属イオンの放出が可能となる。Furthermore, in the electroless plating process, the catheter body is molded from rubber or plastic, and at least the part where the metal film is to be formed is subjected to the electroless plating process in a semi-hardened state, and then the part to which the metal film is applied is hardened. The metal to be plated bites into the resin and does not fall off easily, allowing metal ions to be released over a long period of time.
従って本発明カテーテルはゴムまたはプラスチックで製
造された市販のカテーテルと太さが殆ど変わらないほど
に、前述した金属リング等を装着したカテーテルとは比
較にならないほど薄い金属層を設けることにより、患者
に挿入する際該患者−３＝
に苦痛を与えることなく、しかも長期間にわたり体腔内
に留置しても感染症を併発することがなく、感染症の予
防をも兼ね備えるものである。Therefore, the catheter of the present invention has a metal layer that is almost the same in thickness as commercially available catheters made of rubber or plastic, but is incomparably thinner than the catheters equipped with metal rings, etc., as described above. It does not cause pain to the patient when inserted, and even if it is left in the body cavity for a long period of time, infection does not occur, and it also prevents infection.
なお、本発明は、カテーテル本体の少なくとも体腔内に
挿入される部分に無電解メッキ処理により人体へ刺激を
与えない金属皮膜を設けるので、人体に刺激を与えると
し“ζ裸の状態では使用できなかったゴム製カテーテル
を裸の状態でも使用が可能となり、従って、従来のよう
にゴム本体の表面にテフロンコートを施す必要がなくな
り、ゴム製カテーテルを安価に提供しうる利点もある。In addition, in the present invention, at least the part of the catheter body that is inserted into the body cavity is coated with a metal coating that does not cause irritation to the human body by electroless plating. The rubber catheter can be used even in a naked state, so there is no need to apply a Teflon coat to the surface of the rubber body as in the past, and there is an advantage that the rubber catheter can be provided at low cost.
次に、本発明の詳細な説明する。Next, the present invention will be explained in detail.
本発明は、ゴムまたはプラスチックで成型したカテーテ
ル本体を熱処理することにより半硬化の状態とし、かか
る半硬化状態のカテーテル本体を必要により、無電解メ
ッキ処理に必要な部分を残してマスキングして後、無電
解メッキ処理により金属を析出せしめ、次いで、全体を
更に熱処理して所望の硬さにまで硬化させるカテーテル
の製造方法である。The present invention heat-treats a catheter body molded from rubber or plastic to make it semi-hardened, and if necessary, after masking the semi-hardened catheter body leaving only the parts necessary for electroless plating, This is a method of manufacturing a catheter in which metal is deposited by electroless plating, and then the whole is further heat-treated to harden it to a desired hardness.
このように無電解メッキを半硬化状態のカテーテル本体
に施し、次いで本硬化させることにより、カテーテル表
面に析出した金属皮膜は樹脂に強固に接着されることと
なり、カテーテル使用に際して、または使用中に金属皮
膜が剥がれることがなくなる。By applying electroless plating to the catheter body in a semi-hardened state and then fully curing it, the metal film deposited on the catheter surface will be firmly adhered to the resin, and the metal film will be firmly adhered to the resin when or during use of the catheter. The film will not peel off.
カテーテル本体を成型する樹脂によっては直接無電解メ
ッキ処理を行なっても金属の密着性が悪い場合がある。Depending on the resin used to mold the catheter body, metal adhesion may be poor even if direct electroless plating is performed.
この様な時には、半硬化状態の成型カテーテル本体をア
ルカリ（例えばＮａＯＨ１ＫＯＨ）を１規定以上１０規
定以下と、５ｖｏ １％以上５０ｖｏ１％以下のアルコ
ール（例えばエタノール、プロパツール）を含み残部が
水からなるカテーテル表面処理溶液に浸漬してカテーテ
ル本体表面に親水基を導入したのち無電解メッキを施す
とよい。ここで、アルカリ濃度とアルコール濃度を限定
したのは、これらが共に少ないと親水基の導入が不完全
となり、逆に多過ぎると樹脂を劣化するおそれがあるか
らである。In such cases, the semi-hardened molded catheter body is made of an alkali (e.g. NaOH1KOH) of 1N to 10N and an alcohol (e.g. ethanol, propatool) of 5VO 1% to 50VO 1%, with the remainder being water. It is preferable to immerse the catheter in a surface treatment solution to introduce hydrophilic groups onto the surface of the catheter body, and then perform electroless plating. The reason why the alkali concentration and alcohol concentration are limited here is that if both of these concentrations are too low, the introduction of hydrophilic groups will be incomplete, whereas if they are too high, the resin may deteriorate.
なお、カテーテル本体の先端には管内部と連通する孔が
設けられているので、この孔をマスキングすることなく
無電解メッキ処理を施せば、カテーテル本体の内壁にも
金属皮膜を形成しうろことは勿論である。Note that the tip of the catheter body has a hole that communicates with the inside of the tube, so if electroless plating is applied without masking this hole, a metal film will also be formed on the inner wall of the catheter body, eliminating scales. Of course.
〔実施例１］
生ゴムでカテーテル本体を成型後、熱処理により約６０
％まで半硬化させた。ごの半硬化状態にあるカテーテル
本体をアクチヘータ４４４（メルテソクス社製）でアク
チヘーションし、表面に活性なＰｄを吸着させる。次い
で、ノビガントＨＣ（日本シェーリング社製）に浸漬し
て無電解Ｃｕメッキを施し、カテーテル本体の表面に約
０．２μｍの銅の皮膜を形成した。次いで再び熱処理し
て所望の硬度まで硬化させた。かかる方法で製造したカ
テーテルはゴム表面に均一な銅の皮膜が強固に接着（微
視的には銅粉が均一に被着）されていた。[Example 1] After molding the catheter body with raw rubber, it was heated to approximately 60 mm.
It was semi-cured to %. The catheter body, which is in a semi-hardened state, is activated with actiheter 444 (manufactured by Meltesox), and active Pd is adsorbed on the surface. Next, electroless Cu plating was performed by immersing it in Novigant HC (manufactured by Nippon Schering Co., Ltd.) to form a copper film of about 0.2 μm on the surface of the catheter body. Then, it was heat treated again to harden it to the desired hardness. The catheter manufactured by this method had a uniform copper film firmly adhered to the rubber surface (microscopically, the copper powder was uniformly adhered).
〔実施例２〕
生ゴムでカテーテル本体を成型後、熱処理により約７５
％まで半硬化させた。この半硬化状態にあるカテーテル
本体を、２規定Ｎａ ＯＨ＋２５ ｖｏ１％Ｃ，＋＋、
、ＯＨからなるカテーテル表面処理溶液に浸漬してカテ
ーテル本体表面に親水基を導入したのち、アクチベータ
４４４（メルテックス社製）でアクチベーションし、表
面に活性なＰｄを吸着させた。次いで、ノビガントＨＣ
（日本シェーリング社製）に浸漬して無電解Ｃｕメッキ
を施し、カテーテル本体の表面に約０．４μｍの銅の皮
膜を形成した。次いで、再び熱処理して所望の硬度に硬
化させた。かく処理したカテーテルは銅の皮膜を厚く付
けることができ、しかもカテーテル本来の柔軟性を阻害
することもない。[Example 2] After molding the catheter body with raw rubber, it was heated to approximately 75 mm.
It was semi-cured to %. This semi-hardened catheter body was treated with 2N NaOH+25 vo1%C,++,
, OH was immersed in a catheter surface treatment solution to introduce hydrophilic groups onto the surface of the catheter body, and then activated with Activator 444 (manufactured by Meltex) to adsorb active Pd onto the surface. Next, Novigant HC
(manufactured by Nippon Schering Co., Ltd.) to perform electroless Cu plating to form a copper film of about 0.4 μm on the surface of the catheter body. Then, it was heat treated again to harden it to the desired hardness. Catheters treated in this way can be coated with a thick copper coating without interfering with the inherent flexibility of the catheter.
〔実施例３〕
シリコン樹脂で成型してなるカテーテル本体を熱処理に
より約７０％まで硬化させた。この半硬化カテーテル本
体の人体に挿入される管の部分を除いてマスキングし、
アクチヘータ４４４（メルテックス社製）でアクチベー
ションし、表面に活性なＰｄを吸着させた。次いで、ノ
ビガントＨＣ（日本シェーリング社製）に浸漬して無電
解Ｃｕメッキを施し、カテーテル本体の表面に約０．
３μｍの銅の皮膜を形成した。次いで、再び熱処理して
所望の硬度に硬化させた。かかる方法で製造したカテー
テルはゴム表面に均一な銅の皮膜が強固に接着（微視的
には銅粉が均一に被着）されていた。[Example 3] A catheter body made of silicone resin was cured to about 70% by heat treatment. This semi-hardened catheter body is masked except for the tube part that will be inserted into the human body.
Activation was performed using Actiheta 444 (manufactured by Meltex), and active Pd was adsorbed onto the surface. Next, electroless Cu plating is applied by immersing it in Novigant HC (manufactured by Nippon Schering Co., Ltd.), and the surface of the catheter body is coated with approximately 0.
A 3 μm copper film was formed. Then, it was heat treated again to harden it to the desired hardness. The catheter manufactured by this method had a uniform copper film firmly adhered to the rubber surface (microscopically, the copper powder was uniformly adhered).
〔実施例４〕
生ゴムでカテーテル本体を成型後、熱処理により約６０
％まで半硬化させた。この半硬化状態にあるカテーテル
本体をアクチベータ４４４（メルテックス社製）でアク
チヘーションし、表面に活性なＰｄを吸着させる。次い
で、ＢＥ＞８０１（上村工業株式会社製）に浸漬して無
電解Ｎｉメッキを施し、カテーテル本体の表面に約０．
２μｍのニッケルの皮膜を形成した。次いで再び熱処理
して所望の硬度まで硬化させた。かかる方法で製造した
カテーテルはゴム表面に均一なニッケルの皮膜が強固に
接着（微視的にはニッケル粉が均一に被着）されていた
。[Example 4] After molding the catheter body with raw rubber, it was heated to approximately 60 mm.
It was semi-cured to %. This semi-hardened catheter body is activated with an activator 444 (manufactured by Meltex) to adsorb active Pd on its surface. Next, electroless Ni plating is applied by immersing it in BE>801 (manufactured by Uemura Kogyo Co., Ltd.), and the surface of the catheter body is coated with approximately 0.
A nickel film of 2 μm was formed. Then, it was heat treated again to harden it to the desired hardness. The catheter manufactured by this method had a uniform nickel film firmly adhered to the rubber surface (microscopically, the nickel powder was uniformly adhered).
以上の実施例で製造されたカテーテルは、何れも樹脂表
面に金属の層が均一に膜状に被着されており、しかも、
カテーテル本来の柔軟性も損なうことがなく、カテーテ
ルを人体に挿入しても人体を刺激し、体腔内を損傷する
ようなことはない。The catheters manufactured in the above examples all had a metal layer uniformly adhered to the resin surface in the form of a film, and
The inherent flexibility of the catheter is not impaired, and even if the catheter is inserted into the human body, it will not irritate the human body or damage the inside of the body cavity.
また、金属イオンによる滅菌作用或いは殺菌作用により
、長期にわたって人体に挿入しても感染症を発生ずるこ
ともない。Furthermore, due to the sterilizing or sterilizing effect of the metal ions, no infection will occur even if the device is inserted into the human body for a long period of time.
以上詳述したように、本発明により、カテーテル本体の
少なくとも人体に挿入される部分に、人体に挿入したと
きに該人体を刺激することなく、かつ殺菌作用或いは滅
菌作用を有する金属皮膜を形成することができ、かかる
金属の殺菌作用或いは滅菌作用で感染症が防止でき、し
かも、カテーテル本体に形成される金属皮膜は極めて薄
いため患者への挿入に際しても支障とならず、感染症防
止のための例えば膀胱の洗浄等の手間も軽減でき、しか
も、従来のテフロンコートのものに殺菌作用或いは滅菌
作用を有する金属を付着せしめたものより安価に提供し
うる等の優れた効果がある。As detailed above, according to the present invention, a metal coating is formed on at least the portion of the catheter body to be inserted into the human body, which does not irritate the human body when inserted into the human body and has a bactericidal or sterilizing effect. Infections can be prevented by the bactericidal or sterilizing effect of such metals, and since the metal coating formed on the catheter body is extremely thin, it does not interfere with insertion into a patient, making it an effective material for preventing infections. For example, it has excellent effects such as reducing the labor involved in cleaning the bladder, and can be provided at a lower cost than conventional Teflon-coated products to which a metal having a bactericidal or sterilizing action is attached.
Claims (1)
少なくとも人体の体腔内に挿入される部分の表面層を半
硬化の状態にまで硬化反応させ、該半硬化表面層に無電
解メッキ処理を施して滅菌作用あるいは殺菌作用を有す
る金属皮膜を形成し、次いで、半硬化部分を所望の硬度
に硬化することを特徴とするカテーテルの製造方法。The catheter body is molded from rubber or plastic,
At least the surface layer of the portion to be inserted into the body cavity of the human body is hardened to a semi-hardened state, and the semi-hardened surface layer is subjected to an electroless plating treatment to form a metal film having a sterilizing or bactericidal action, A method for manufacturing a catheter, comprising: then hardening the semi-hardened portion to a desired hardness.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2332030A JPH04197363A (en) | 1990-11-29 | 1990-11-29 | Manufacture of catheter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2332030A JPH04197363A (en) | 1990-11-29 | 1990-11-29 | Manufacture of catheter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH04197363A true JPH04197363A (en) | 1992-07-16 |
Family
ID=18250356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2332030A Pending JPH04197363A (en) | 1990-11-29 | 1990-11-29 | Manufacture of catheter |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH04197363A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5490938A (en) * | 1993-12-20 | 1996-02-13 | Biopolymerix, Inc. | Liquid dispenser for sterile solutions |
| US5817325A (en) * | 1996-10-28 | 1998-10-06 | Biopolymerix, Inc. | Contact-killing antimicrobial devices |
| US5849311A (en) * | 1996-10-28 | 1998-12-15 | Biopolymerix, Inc. | Contact-killing non-leaching antimicrobial materials |
| US5869073A (en) * | 1993-12-20 | 1999-02-09 | Biopolymerix, Inc | Antimicrobial liquid compositions and methods for using them |
| US6180584B1 (en) | 1998-02-12 | 2001-01-30 | Surfacine Development Company, Llc | Disinfectant composition providing sustained residual biocidal action |
| US7288264B1 (en) | 1993-12-20 | 2007-10-30 | Surfacine Development Company, L.L.C. | Contact-killing antimicrobial devices |
| WO2010090098A1 (en) * | 2009-02-09 | 2010-08-12 | テルモ株式会社 | Method for producing antimicrobial medical instrument, and antimicrobial medical instrument |
-
1990
- 1990-11-29 JP JP2332030A patent/JPH04197363A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5490938A (en) * | 1993-12-20 | 1996-02-13 | Biopolymerix, Inc. | Liquid dispenser for sterile solutions |
| US5869073A (en) * | 1993-12-20 | 1999-02-09 | Biopolymerix, Inc | Antimicrobial liquid compositions and methods for using them |
| US6030632A (en) * | 1993-12-20 | 2000-02-29 | Biopolymerix And Surfacine Development Company | Non-leaching antimicrobial films |
| US6126931A (en) * | 1993-12-20 | 2000-10-03 | Surfacine Development Company, Llc | Contact-killing antimicrobial devices |
| US6264936B1 (en) | 1993-12-20 | 2001-07-24 | Biopolymerix, Inc. | Contact-killing non-leaching antimicrobial materials |
| US7288264B1 (en) | 1993-12-20 | 2007-10-30 | Surfacine Development Company, L.L.C. | Contact-killing antimicrobial devices |
| US5817325A (en) * | 1996-10-28 | 1998-10-06 | Biopolymerix, Inc. | Contact-killing antimicrobial devices |
| US5849311A (en) * | 1996-10-28 | 1998-12-15 | Biopolymerix, Inc. | Contact-killing non-leaching antimicrobial materials |
| US6180584B1 (en) | 1998-02-12 | 2001-01-30 | Surfacine Development Company, Llc | Disinfectant composition providing sustained residual biocidal action |
| WO2010090098A1 (en) * | 2009-02-09 | 2010-08-12 | テルモ株式会社 | Method for producing antimicrobial medical instrument, and antimicrobial medical instrument |
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