JPH0417845A - Thrombus dissolving therapy apparatus - Google Patents

Abstract

PURPOSE:To enable the fixing of an ultrasonic vibrator at the optimum position by providing an envelope dividable at least in two being as opposed to a thrombus part invivo from outside the body and an ultrasonic wave generation means which is built into the envelope free to move and irradiates an ultrasonic wave to the thrombus part to allow the arrangement of the vibrator with adjustable movement thereof optimally. CONSTITUTION:An ultrasonic gel or like is applied on the circumferential surface of a foot 2 having a part at which a thrombus 8 is developed and then, the part is covered with half cylinders 1a and 1b each having a pair of pouches 6a and 6b on the internal surface of which an ultrasonic gel or the like is applied likewise and both the cylinders are locked together with a key 11. Then, an ultrasonic wave transmitting agent 12 such as deaired water is injected into the pouches 6a and 6b through tubes 13a and 13b with a pump not illustrated and this apparatus 1 is made to press on the perimeter of a thrombus affected position optimally. In this case, the deaired water to be fed into the pouches 6a and 6b is adjusted depending on the diameter of a foot, which allows the fixing of the apparatus 1 accurately regardless of the diameter of the foot. On the other hand, a catheter 9 is inserted dermally into a blood vessel 7 affected by thrombus 8 and the tip thereof gets closer to the part of the thrombus 8.

Description

[Detailed Description of the Invention] [Industrial Application Field] The present invention relates to a thrombolytic treatment device, more specifically, a thrombolytic treatment device that injects a dissolving agent into the site of a blood clot formed in a blood vessel in the body and irradiates it with ultrasonic waves from outside the body. The present invention relates to a thrombolytic treatment device that promotes the dissolution of blood clots.

[Prior Art] Conventionally, this type of thrombolytic treatment device involves, for example, inserting a catheter toward the site of a thrombus that has formed in a blood vessel, injecting a dissolving agent through the catheter, and then injecting a dissolving agent into the site of the thrombus from the outside. Some methods use ultrasonic waves to promote the dissolution of blood clots by a dissolving agent. However, in this treatment device, nothing is known about how to fix or move the ultrasonic wave generating means, especially the ultrasonic transducer that generates the ultrasonic waves.

[Problem to be solved by the invention] However, depending on the location of the affected area where the thrombus has occurred, simply applying ultrasonic waves from the outside after injecting the dissolving agent may not be able to achieve much of the effect of promoting dissolution. Sometimes there isn't.

In other words, when a blood clot occurs in the upper and lower parts of the hands or feet, the outer circumferential surface of the affected area is rounded and there are bones inside, so ultrasound should not be applied to these bones. I get interrupted.

Therefore, it is necessary to emit ultrasonic waves while avoiding this, or it is necessary to dispose the ultrasonic transducer in a movable manner in order to emit ultrasonic waves while avoiding these bones and the like.

The purpose of the present invention is to solve the above-mentioned drawbacks of conventional thrombolytic treatment devices of this type, and to dissolve a thrombus by irradiating external ultrasonic waves toward the thrombus site where a thrombus is generated and a dissolving agent is injected. An object of the present invention is to provide a thrombolytic treatment device in which an ultrasonic transducer can be suitably arranged to be movable and can be fixed at an optimal position.

[Means for Solving the Problems and Effects] In order to achieve the above object, the present invention provides a thrombus treatment method in which a dissolving agent is injected into the site of a thrombus formed in the body, and ultrasonic waves are irradiated from outside the body to promote dissolution of the thrombus. In the lytic treatment device, an enclosure that can be divided into at least two parts and faces the thrombus site from outside the body, and an ultrasonic wave that is movably built into the enclosure and that irradiates the thrombus site with ultrasound waves. The ultrasonic wave generator is characterized in that the ultrasonic wave generating means is movably built into the surrounding body after surrounding the outside of the human body part where the thrombus site is located with the surrounding body. is moved to the optimal position and appropriate ultrasound is generated to efficiently promote the dissolution of the thrombus.

Embodiment FIGS. 1 to 3 respectively show a sectional view, an external view, and an exploded perspective view of a thrombolytic treatment device showing a first embodiment of the present invention.

The thrombolytic treatment device 1 in this embodiment is suitably applied to thrombi generated inside the hands, feet, etc., and as shown in FIG. 2, the main body surrounds the hands, feet, etc. A thick cylinder having an inner diameter sufficient for the purpose of the invention is vertically divided into two halves, and the pair of semicircular half cylinders 1a and lb have a hook member 10 and a key provided at their outer ends. 11(
(see FIG. 3) so that they can be opened and closed together. As shown in FIG.
A plurality of skewer-shaped grooves 2b are formed perpendicularly to the grooves a2a.

Ultrasonic transducers 5a and 5b are fixed to the lower end portions of the ultrasonic transducers 2b via operating knobs 4a and 4b (see FIG. 1).
can be moved freely.

As shown in FIG. 1, the inner surfaces of the semi-cylindrical bodies 1a and 1b are provided with a well-known pouch 6a made of a stretchable and flexible membrane filled with an ultrasonic transmitting agent 12.

6b is interposed. The pouches 6a, 6b are filled with an ultrasonic transmitting agent 12, such as deaerated water, by a pump (not shown) through tubes 13a13b, and the device main body l and legs 2 are suitably brought into close contact with each other so as to prevent air gaps from forming. It is designed to transmit ultrasonic waves to the affected area of the blood clot.

The thrombolytic treatment device 1 of this embodiment configured as described above is used as follows. First, as shown in Figs. 1 and 2, an ultrasonic jelly or the like is applied to the circumferential surface of the leg 2 in the area where the thrombus 8 has occurred, and then that area is coated with the above-mentioned pairs, the inner surface of which is also coated with an ultrasonic jelly or the like. The half-cylindrical bodies 1a and 1b having pouches 6a and 6b are covered and locked together with a key 11.

Next, an ultrasonic transmitting agent 12 such as degassed water is injected into the pouches 6a and 6b from a pump (not shown) through the tubes 13a and 13b, and the device 1 is suitably pressed around the location of the affected part of the blood clot. I'll do what I do. In this case, pouch 6a depends on the thickness of the foot.

By adjusting the amount of degassed water fed into 6b, it is possible to securely fix the device 1 even to a foot as thick as 6b.

On the other hand, a catheter 9 is percutaneously inserted into the blood vessel 7 where the thrombus 8 has occurred, as shown in FIG. 1, and its tip is brought close to the thrombus site. And with the same catheter 9,
For example, a thrombolytic agent such as urokinase is injected. At that time, if the positions of the ultrasonic transducers 5a and 5b attached to the semi-cylindrical bodies la and lb are obstructed by bones etc. and the thrombus cannot be irradiated properly, the ultrasonic transducers 5
a, 5b into the groove 2 via the operating knobs 4a, 4b.
All you have to do is move it to the optimal irradiation position along lines a and 2b.

That is, the ultrasonic transducers 5a and 5b are manually moved and placed at positions where the thrombolytic effect of the ultrasonic waves generated by them is always the highest.

Although the ultrasonic transducers 5a and 5b are designed to be able to be moved manually, it is of course possible to electrically control their movement using power from a motor or the like. In this case, an ultrasonic transducer with a higher frequency (3 MHz to 10 MHz) than that for therapeutic use is separately built in for observation of the thrombus position, and based on the observation results by the ultrasonic transducer, the therapeutic ultrasonic transducer 5a, 5b may be moved automatically. In this case, as shown in FIG. 4, the observation ultrasonic transducer 16 is placed on the inner surface of the curved support plate 16a, and after the observation signal is processed by the DSC 14 (digital scan converter), the CPU 18 The position of the therapeutic transducer 5a (5b) may be suitably moved by the position control means 17 based on the signal via the position control means 17. At the same time, the therapeutic ultrasonic output of the ultrasonic transducer 5a is also controlled by the CPU 18 through the amplifier 15.

FIG. 5 is a schematic external view showing the state of use of the thrombolytic treatment device according to the second embodiment of the present invention. The thrombolytic treatment device 20 in this embodiment has an upper and lower half-cylinder body 1a divided into two in the thrombolytic treatment device 1 in the first embodiment.
, lb, the half cylinder 20 corresponding to the upper half cylinder 1a
Regarding H, it is configured exactly the same as the half cylinder 1a, or instead of the half cylinder corresponding to the lower half cylinder 1b, the upper surface is a half angle whose upper surface is a curved surface similar to the curved inner surface of the half cylinder 1b. The difference is that it is formed of a column 21.

This half-prismatic body 21 is attached to a treatment bed 22. The rest of the configuration is exactly the same as the thrombolytic treatment device 1 in the first embodiment, so
Identical members are designated by the same reference numerals, and their explanations will be omitted.

When using the thrombolytic treatment device 20 configured as described above, the key 11 is released, the upper half cylinder 20a is removed or opened, and the upper half cylinder 20a and the half prism body 2 are removed.
1, each internal pouch 23a.

At the same time as applying ultrasonic jelly or the like to 23b, apply ultrasonic jelly or the like to the peripheral surface of the leg corresponding to the thrombus site,
After that, the half-cylindrical body 20a is closed. The subsequent operations are as described in step 1 above.
Since it is completely the same as the case of the thrombolytic treatment device 1 in the embodiment, the explanation thereof will be omitted.

As described above, according to the thrombolytic treatment device 20 of this embodiment, the patient only needs to place his or her feet on the curved surface of the half-prismatic body 21, which serves as a footrest mounted on the treatment table.
You can get faster emergency treatment or more effective results.

[Effects of the Invention] As explained above, according to the present invention, depending on the position in the blood vessel of the human body where a thrombus has conventionally occurred, the effect of ultrasonic irradiation for accelerating the injected thrombolytic agent cannot be sufficiently obtained. In contrast, in the present invention, ultrasonic irradiation can be reliably applied to any thrombus location, and its dissolution promoting effect can be fully expected. Moreover, in order to align the ultrasonic transducer with the thrombus position, the operating knob can be moved along the guide groove without moving the entire device body. In addition, this makes it possible to provide a thrombolytic therapy device that eliminates the drawbacks of conventional thrombolytic therapy devices of this type, in which the main body of the device does not need to be moved once it is attached and is very easy to operate.

[Brief explanation of the drawing]

FIG. 1 is a cross-sectional view of a thrombolytic treatment device showing a first embodiment of the present invention, FIG. 2 is a schematic external view showing how the thrombolytic treatment device of FIG. 1 is used, and FIG. FIG. 4 is an exploded perspective view showing a state in which the upper and lower parts of the thrombolytic treatment device in FIG. 2 are separated, and FIG.
A schematic configuration diagram showing an example in which an ultrasonic transducer for observation is further attached to the ultrasonic treatment device shown in the embodiment. FIG. 5 is a schematic external view of a thrombolytic treatment device showing a second embodiment of the present invention. . 1.20... Thrombolytic treatment device la, l
b, 20a...Half cylinder body (enveloping body) 2...
......Feet 4a 4b...Operation knob

Claims (1)

[Claims] (1) A thrombolytic treatment device that injects a dissolving agent into the site of a blood clot formed in the body and irradiates ultrasound from outside the body to promote the dissolution of the blood clot, which can be divided into at least two parts and A thrombolytic treatment device comprising: an enclosure facing from outside the body; and an ultrasound generating means movably built into the enclosure for irradiating ultrasonic waves to the thrombus site.