JPH04159208A - Hair production accelerator - Google Patents
Hair production acceleratorInfo
- Publication number
- JPH04159208A JPH04159208A JP28539190A JP28539190A JPH04159208A JP H04159208 A JPH04159208 A JP H04159208A JP 28539190 A JP28539190 A JP 28539190A JP 28539190 A JP28539190 A JP 28539190A JP H04159208 A JPH04159208 A JP H04159208A
- Authority
- JP
- Japan
- Prior art keywords
- hair
- accelerator
- composition
- effects
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004209 hair Anatomy 0.000 title abstract description 50
- 238000004519 manufacturing process Methods 0.000 title abstract 4
- 239000000126 substance Substances 0.000 claims abstract description 8
- 239000008280 blood Substances 0.000 claims abstract description 6
- 210000004369 blood Anatomy 0.000 claims abstract description 6
- 230000003779 hair growth Effects 0.000 claims description 23
- 241000283690 Bos taurus Species 0.000 claims description 5
- 239000007952 growth promoter Substances 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 21
- 201000004384 Alopecia Diseases 0.000 abstract description 9
- 239000000203 mixture Substances 0.000 abstract description 7
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract description 6
- 229910052760 oxygen Inorganic materials 0.000 abstract description 6
- 239000001301 oxygen Substances 0.000 abstract description 6
- 230000004060 metabolic process Effects 0.000 abstract description 5
- 230000003213 activating effect Effects 0.000 abstract description 4
- 239000006071 cream Substances 0.000 abstract description 4
- 239000000839 emulsion Substances 0.000 abstract description 4
- 239000006210 lotion Substances 0.000 abstract description 4
- 230000001766 physiological effect Effects 0.000 abstract description 4
- 230000001737 promoting effect Effects 0.000 abstract description 4
- 230000001965 increasing effect Effects 0.000 abstract description 3
- 231100000360 alopecia Toxicity 0.000 abstract description 2
- 238000002360 preparation method Methods 0.000 abstract description 2
- 239000002453 shampoo Substances 0.000 abstract description 2
- 230000001256 tonic effect Effects 0.000 abstract description 2
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 230000003834 intracellular effect Effects 0.000 abstract 1
- 238000002156 mixing Methods 0.000 abstract 1
- 230000000474 nursing effect Effects 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 230000000384 rearing effect Effects 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 description 8
- 230000003676 hair loss Effects 0.000 description 7
- 208000024963 hair loss Diseases 0.000 description 7
- 230000017531 blood circulation Effects 0.000 description 6
- 210000004027 cell Anatomy 0.000 description 6
- 238000010521 absorption reaction Methods 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 238000011282 treatment Methods 0.000 description 4
- 231100000957 no side effect Toxicity 0.000 description 3
- 239000003918 blood extract Substances 0.000 description 2
- 244000309466 calf Species 0.000 description 2
- 230000004663 cell proliferation Effects 0.000 description 2
- 230000003511 endothelial effect Effects 0.000 description 2
- 239000003676 hair preparation Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 210000004088 microvessel Anatomy 0.000 description 2
- 210000004761 scalp Anatomy 0.000 description 2
- 208000003024 Diffuse alopecia Diseases 0.000 description 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
- 235000011613 Pinus brutia Nutrition 0.000 description 1
- 241000018646 Pinus brutia Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 208000004631 alopecia areata Diseases 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 150000008237 desoxyribosides Chemical class 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 210000004709 eyebrow Anatomy 0.000 description 1
- 230000031774 hair cycle Effects 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 230000003658 preventing hair loss Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- -1 steroid compounds Chemical class 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000003797 telogen phase Effects 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 235000015961 tonic Nutrition 0.000 description 1
- 229960000716 tonics Drugs 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
Description
【発明の詳細な説明】 〈産業上の利用分野〉 幼牛血液抽出物質を主体とする頭髪用製剤に関する。[Detailed description of the invention] <Industrial application field> This invention relates to a hair preparation containing a substance extracted from young bovine blood.
利用分野は、医療用から一般大衆向の発毛料に用いるこ
とが出来る。It can be used for medical purposes as well as hair growth agents for the general public.
〈従来の技術〉
従来、主として頭髪の脱毛の防止、増毛を計るべく多く
の治療、処置が行なわれている。例えば、毛母基を活性
化させるための処理剤、ステロイド系化合物による発毛
剤。<Prior Art> Conventionally, many treatments and treatments have been carried out mainly to prevent hair loss and increase hair growth. For example, treatment agents for activating hair matrix, and hair growth agents using steroid compounds.
前者は、多種の液剤の他、活性化を促すための機械設備
が必要で、時間と手間がかかり、後者は、ホルモン剤が
ゆえに副作用、その他の影響を考えると好ましくない。The former requires various liquid preparations and mechanical equipment to promote activation, which is time-consuming and labor-intensive, while the latter is undesirable in view of side effects and other effects because it is a hormonal drug.
また近年では、養毛化粧料の適要と共にブラシ（パッテ
ィングブラシ）を併用して頭皮の血行をマツサージまた
は、パッティングにより促進することが普及し目的とす
る養毛効果が得られることが知られている。しかし、期
待される程の育毛、発毛効果は得られず、頭皮まで傷つ
けかねなかった。In addition, in recent years, it has become popular to apply hair-growth cosmetics and use a brush (patting brush) to promote blood circulation in the scalp through pine surge or patting, and it is known that the desired hair-growth effect can be achieved. There is. However, the hair growth effect that was expected could not be obtained, and the scalp could even be damaged.
〈発明が解決しようとする課題〉
本発明は、人体での必要箇所に塗布することで簡単に抜
は毛を防止し、また顕著な増毛養毛効果が得られ、副作
用も全くない安全な発毛、養毛剤を提供することを目的
とする。<Problems to be Solved by the Invention> The present invention provides a safe hair growth method that can easily prevent hair loss by applying it to the necessary parts of the human body, provide a remarkable hair growth effect, and have no side effects. The purpose is to provide hair and hair nourishing agents.
〈課題を解決するための手段〉
一般に発毛促進剤として使用される物質は、優れた主的
効果を呈すると共に比較的長期間にわたり連用すること
から特に安全性が高いことが要求される。<Means for Solving the Problems> Substances generally used as hair growth promoters are required to have excellent main effects and to be particularly safe since they are used continuously for a relatively long period of time.
発明者は古くから医療、治療に幅広く使用されている幼
牛血液抽出物質を検索した。The inventor searched for a substance extracted from baby cow blood, which has been widely used in medicine and treatment since ancient times.
この物質は、１９５５年スイスのＪｓｅｇｅｒ、 １ｌ
ｆｌらにより幼牛血液中から細織呼吸促進物として発見
抽出されたもので、その成分は、多数の未知ポリペブタ
イト、デスオキシリボサイド、各種アミノ酸などの有機
成分および無機成分が含まれている。This substance was published in 1955 by Jseger in Switzerland, 1l
It was discovered and extracted from the blood of young cattle by Fl et al. as a fine respiration promoter, and its components include a large number of unknown organic and inorganic components such as polypebutite, desoxyriboside, and various amino acids.
この幼牛血液抽出物質は、生体細織の酸素吸収能を高め
て新陳代謝を促進し、細胞内皮系を賦活化、また細胞増
殖作用などの種々の生理活性を有することが認められて
いる。This baby bovine blood extract has been recognized to have various physiological activities such as increasing the oxygen absorption capacity of biological tissue, promoting metabolism, activating the cell endothelial system, and cell proliferation.
（文献所在）
１） Ｊｉｅｇｅｒ、に、Ｈｅ（！＋、 ： Ｋ１１
ｎ、 Ｗｓｃｈｒ、、 ３６゜４４１、１９５８
発明者は、この物質が目的にかなうことを見出し完成し
た。(Reference location) 1) Jieger, Ni, He (!+, : K11
n, Wschr, 36°441, 1958 The inventor discovered that this substance served the purpose and perfected it.
本発明の組成物は溶液・エマルジョンのいずれの形態で
も使用することが出来る。The composition of the present invention can be used in either solution or emulsion form.
例えば、ヘアーローション、ヘアークリーム。For example, hair lotion, hair cream.
乳液、ヘアートニック、ヘアーシャンプー、ヘアーリン
スなどの頭髪用製剤中に配合することが出来る。It can be incorporated into hair preparations such as emulsions, hair tonics, hair shampoos, and hair rinses.
く作 用〉
毛髪は皮膚の生産物であり毛色の底部の毛母基でできて
いる表皮細胞から生じる毛母基での多数の細胞が急速に
増殖して、毛が伸長していることは判明している。一定
の周期で毛母基の活動が強くなったり弱くなったりする
毛周期があり、休止期を経て新宅が成長する。Hair is a product of the skin, and the growth of hair is caused by the rapid proliferation of a large number of cells in the hair matrix, which originate from epidermal cells that are made of the hair matrix at the bottom of the hair. It's clear. There is a hair cycle in which the activity of the hair matrix becomes stronger and weaker at regular intervals, and new hair grows after a resting period.
この際、休止期において、毛母基の活動が中止してしま
うと新宅が生えないことになる。At this time, if the activity of the hair matrix ceases during the telogen phase, new hair will not grow.
毛髪が発毛する絶対的な条件として血行とともに、毛母
系細胞の活発な活動が必要であり、毛母系細胞が分裂す
るとき酸素が不可欠になる。The absolute conditions for hair growth are blood circulation and active activity of hair matrix cells, and oxygen is essential when hair matrix cells divide.
本発明での発毛用組成物によれば、これを皮膚に（外用
的に供給）塗布すると良い。すると皮膚組織において毛
母系細胞の酸素吸収能を高めて新陳代謝を促進し、組織
機能を高め、微小血管の血行循環を改善し血行をよくす
ることにより毛根活性を刺激し、毛髪を生えやすい状態
にする。According to the hair growth composition of the present invention, it is preferable to apply it to the skin (supplied externally). Then, in the skin tissue, it increases the oxygen absorption capacity of hair matrix cells, promotes metabolism, enhances tissue function, improves blood circulation in microvessels, stimulates hair root activity, and facilitates hair growth. do.
また、細胞増殖作用による細胞生存期間の延長によって
脱毛防止にも有効である。It is also effective in preventing hair loss by extending the cell survival period due to its cell proliferation effect.
本発明の発毛用組成物が生化学的にどのような反応に関
与し、脱毛を防止し、発毛、増毛を促進するのか、その
生化学的作用、機構自体は明らかではない。The biochemical action and mechanism of the hair growth composition of the present invention involved in the biochemical reactions to prevent hair loss and promote hair growth and thickening are not clear.
しかしながら、発育最成期の幼牛血液の除蛋白抽出物か
ら発見された物質で、生体の組織の酸素吸収能を高めて
新陳代謝を促進し、細胞内皮系を賦活化するなどの種々
の生理活性を有することにより、有効で副作用のないき
わめて安全な発毛。However, it is a substance discovered from the deproteinized extract of the blood of calves at the peak of their growth, and it has various physiological activities such as increasing the oxygen absorption capacity of living tissues, promoting metabolism, and activating the cellular endothelial system. Effective and extremely safe hair growth with no side effects.
増毛、養毛促進効果が実現されると推定される。It is estimated that the effect of promoting hair growth and hair growth is achieved.
〈発明の効果〉
本発明の発毛用組成物によれば、幼牛血液抽出物質が皮
膚組織において、組織の酸素吸収能を高めて新陳代謝を
促進し、組織機能を高め、微小血管の血行循環を改善す
ることにより血行を良くし、毛根活性を刺激することで
毛髪を生えやすい状態にし、安全で副作用を伴わず、脱
毛、白髪を防止し、発毛、増毛、養毛促進に著しい効果
を認める。<Effects of the Invention> According to the hair growth composition of the present invention, the calf blood extract enhances the oxygen absorption capacity of the tissue in the skin tissue, promotes metabolism, enhances tissue function, and improves blood circulation in microvessels. It improves blood circulation by improving blood circulation, stimulates hair root activity, makes hair easier to grow, is safe and has no side effects, prevents hair loss and gray hair, and has remarkable effects on hair growth, hair growth, and hair growth. admit.
〈実 施 例〉
本発明の原理を仮説として作成したヘアーローションを
ボランティアの被験者（２４才男性）に実施したところ
、２ケ月で毛根よりうぶ毛が生じ、３〜４ケ月をすぎる
と軟毛からつややかで太い硬毛に変化した。<Example> When a hair lotion created based on the principle of the present invention was applied to a volunteer test subject (24-year-old male), downy hair appeared from the hair root in 2 months, and after 3 to 4 months, the hair changed from soft to shiny. It changed into thick terminal hair.
また、脱毛の著しく激しかった被験者（３２才男性）に
塗布したところ１ケ月過ぎたころより脱毛数が減少しは
じめ、２ケ月をすぎると正常値の１日１００本前後にと
どまった。Furthermore, when the product was applied to a test subject (a 32-year-old male) who had extremely severe hair loss, the number of hair loss started to decrease after one month, and after two months, it remained at the normal level of around 100 hairs per day.
他の被験者１３人（うち白髪３人）に実施したところ、
全員に効果が認められ、白髪も減少を認めた。When conducted on 13 other subjects (including 3 with white hair),
The effect was observed in all patients, and a reduction in gray hair was also observed.
またうすいまゆ毛の被験者５人（男性３１女性２）に本
発明のクリームを塗布したところ３週間で、はえていな
かった毛根より発毛しはじめ、２ケ月をすぎると全員が
太く濃くなった。Furthermore, when the cream of the present invention was applied to five test subjects (31 men and 2 women) with thin eyebrows, hair began to grow from the roots where it had not grown within 3 weeks, and after 2 months, the hair became thicker and thicker in all of them.
こうした皮膚への直接の塗布によっても皮膚疾患その他
の副作用は全く認められなかった。Even when applied directly to the skin, no skin diseases or other side effects were observed.
こうした養毛効果は、脱毛の原因が円形脱毛症。These hair-nourishing effects are due to alopecia areata, which is the cause of hair loss.
萎縮性脱毛症、びまん性脱毛症、白髪のいずれであって
も同様の効果が得られたものである。Similar effects were obtained for atrophic alopecia, diffuse alopecia, and gray hair.
実施した発毛促進剤の調整
ローション
ク リ − ム
特許出願人 有限会社カッムラ
手続補正書（方式）
％式％［１
１、事件の表示
平成２年特許願第２−２８５３９１号
２、発明の名称 発し促進剤
３、補正をする者
事件との間質 特許出願人
住所（居所） 大阪府堺市南瓦町１−１９グランビ
ルト堺東＋０１
氏名（名称） 有限会社カッムラ
住所（居所）Adjusted hair growth promoter lotion cream patent applicant Kamura Co., Ltd. Procedural amendment (method) % formula % [1 1, Display of the case 1990 Patent Application No. 2-285391 2, Title of the invention Issuance accelerator 3, interstitial relationship with the amended person's case Patent applicant address (residence) Granbilt Sakai Higashi +01, 1-19 Minamiwara-cho, Sakai-shi, Osaka Name (name) Kamura Co., Ltd. Address (residence)
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2285391A JPH066526B2 (en) | 1990-10-22 | 1990-10-22 | Hair growth promoter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2285391A JPH066526B2 (en) | 1990-10-22 | 1990-10-22 | Hair growth promoter |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH04159208A true JPH04159208A (en) | 1992-06-02 |
| JPH066526B2 JPH066526B2 (en) | 1994-01-26 |
Family
ID=17690934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2285391A Expired - Lifetime JPH066526B2 (en) | 1990-10-22 | 1990-10-22 | Hair growth promoter |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH066526B2 (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63139113A (en) * | 1986-11-29 | 1988-06-10 | Shiseido Co Ltd | Hair cosmetic |
| JPH03123722A (en) * | 1989-02-21 | 1991-05-27 | Masaru Ogino | Promotion of hair growth |
-
1990
- 1990-10-22 JP JP2285391A patent/JPH066526B2/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63139113A (en) * | 1986-11-29 | 1988-06-10 | Shiseido Co Ltd | Hair cosmetic |
| JPH03123722A (en) * | 1989-02-21 | 1991-05-27 | Masaru Ogino | Promotion of hair growth |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH066526B2 (en) | 1994-01-26 |
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