JPH0371909B2 - - Google Patents
Info
- Publication number
- JPH0371909B2 JPH0371909B2 JP62271098A JP27109887A JPH0371909B2 JP H0371909 B2 JPH0371909 B2 JP H0371909B2 JP 62271098 A JP62271098 A JP 62271098A JP 27109887 A JP27109887 A JP 27109887A JP H0371909 B2 JPH0371909 B2 JP H0371909B2
- Authority
- JP
- Japan
- Prior art keywords
- frequency
- coil
- current
- induced current
- frequency magnetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000010438 heat treatment Methods 0.000 claims description 20
- 206010020843 Hyperthermia Diseases 0.000 claims description 16
- 230000036031 hyperthermia Effects 0.000 claims description 16
- 230000006698 induction Effects 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 9
- 230000004907 flux Effects 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 5
- 201000011510 cancer Diseases 0.000 description 9
- 238000010586 diagram Methods 0.000 description 7
- 206010028980 Neoplasm Diseases 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 238000005481 NMR spectroscopy Methods 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000009442 healing mechanism Effects 0.000 description 1
- 238000009533 lab test Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000000015 thermotherapy Methods 0.000 description 1
- 238000003325 tomography Methods 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
- A61N1/403—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals for thermotherapy, e.g. hyperthermia
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Electrotherapy Devices (AREA)
- Radiation-Therapy Devices (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Description
【発明の詳細な説明】
（産業上の利用分野）
本発明は、高周波磁場によつて発生する誘導電
流を用いて患部を加温する高周波誘導加温法によ
るハイパーサーミア装置に関する。DETAILED DESCRIPTION OF THE INVENTION (Field of Industrial Application) The present invention relates to a hyperthermia device using a high-frequency induction heating method that heats an affected area using an induced current generated by a high-frequency magnetic field.
（従来の技術）
癌等の悪性腫瘍の温熱療法はハイパーサーミア
と呼称されている。最近臨床又は実験室での生物
資料による実験によつて治癒のメカニズムの解明
が進むにつれて、世界各国でハイパーサーミアの
使用が盛んになつてきた。治癒のメカニズムがす
べて解明されているわけではないが、正常組織に
無害であつて悪性腫瘍は影響を受ける温度条件が
あること、又、放射線治療等で損傷を受けた悪性
腫瘍組織の回復を阻害し、死滅させる温度条件が
ある等のことが分つてきて用いられるようになつ
た。ハイパーサーミアのための装置は加温の手段
により異なる数種の装置があるが、ここでは高周
波誘導加温によるハイパーサーミア装置について
考察する。本方式のハイパーサーミア装置は、高
周波磁束を生体中に貫通させ、磁界の周囲に発生
する誘導電流により加温する装置である。第４図
に従来のハイパーサーミア装置による加温の状態
を示す。図において、高周波磁界を生体に供給す
るアプリケータである1Tコイル１を胴体２の周
囲に設置して、1Tコイル１に高周波発生器３か
ら高周波電流を供給すると、紙面に垂直な方向の
高周波磁界が発生して胴体２を貫通し、胴体２の
周辺部に誘導電流４が流れる。(Prior Art) Thermotherapy for malignant tumors such as cancer is called hyperthermia. Recently, as the mechanism of healing has been elucidated through clinical and laboratory experiments using biological materials, the use of hyperthermia has become popular around the world. Although not all healing mechanisms have been elucidated, there are temperature conditions that are harmless to normal tissue but affect malignant tumors, and that it inhibits the recovery of malignant tumor tissue damaged by radiation therapy, etc. However, it came to be used after it was discovered that there are temperature conditions that kill it. There are several types of hyperthermia devices that differ depending on the means of heating, but here we will consider a hyperthermia device that uses high-frequency induction heating. This type of hyperthermia device is a device that penetrates a high-frequency magnetic flux into a living body and heats it by an induced current generated around the magnetic field. FIG. 4 shows a heating state using a conventional hyperthermia device. In the figure, when a 1T coil 1, which is an applicator that supplies a high-frequency magnetic field to a living body, is installed around the body 2 and a high-frequency current is supplied from a high-frequency generator 3 to the 1T coil 1, a high-frequency magnetic field is generated in a direction perpendicular to the plane of the paper. is generated, passes through the fuselage 2, and an induced current 4 flows around the fuselage 2.
（発明が解決しようとする問題点）
ところで、癌等の悪性腫瘍の治療のためには加
温部位は患部のみに限定することが望まれてい
る。しかし、高周波誘導加温ではその加温部位の
局所化を行える技術は全く無く、現在まで実用化
されている1Tコイルによる高周波誘導加温装置
では、その中に挿入される胴体等の周辺部が悪性
腫瘍等の病変部の有無に拘らず一様に加温されて
しまう。(Problems to be Solved by the Invention) Incidentally, for the treatment of malignant tumors such as cancer, it is desirable to limit the area to be heated only to the affected area. However, in high-frequency induction heating, there is no technology that can localize the heated area, and the high-frequency induction heating devices using 1T coils that have been put into practical use to date only cover the surrounding areas of the torso etc. that are inserted into it. Heat is applied uniformly regardless of the presence or absence of a lesion such as a malignant tumor.
本発明は上記の問題点に鑑みてなされたもの
で、その目的は、加温する部分は体表付近に限ら
れるものの、必要な部分のみを加温することので
きる高周波誘導加温法によるハイパーサーミア装
置を実現することにある。 The present invention was made in view of the above-mentioned problems, and its purpose is to use hyperthermia using a high-frequency induction heating method that can heat only the necessary parts, although the heating part is limited to the vicinity of the body surface. The purpose is to realize the device.
（問題点を解決するための手段）
前記の問題点を解決する本発明は、周波磁場に
よつて発生する誘導電流を用いて患部を加温する
高周波誘導加温法によるハイパーサーミア装置に
おいて、高周波電流を発生する高周波発生器と、
該高周波発生器の出力する高周波電流が供給さ
れ、生体が載置される空間に向けて高周波磁束を
発生するコイルと、生体組織より電気伝導度の高
い液体が内部に充満され、前記コイルによる高周
波磁束の周囲に生じる誘導電流の環状の電流路の
内、加温を必要とする部分以外の電流路を形成す
るパツドとを有することを特徴とするものであ
る。(Means for Solving the Problems) The present invention solves the above-mentioned problems in a hyperthermia device using a high-frequency induction heating method that uses induced currents generated by a frequency magnetic field to heat an affected area. a high frequency generator that generates
A coil is supplied with the high-frequency current output from the high-frequency generator and generates high-frequency magnetic flux toward the space in which the living body is placed, and the inside is filled with a liquid that has higher electrical conductivity than the living tissue, and the high-frequency current generated by the coil is filled. This device is characterized by having a pad that forms a current path other than a portion that requires heating among the annular current path of the induced current generated around the magnetic flux.
（作用）
高周波発生器からコイルに高周波電流が供給さ
れ、生体が載置される空間に向けて高周波磁束が
発生する。これにより、高周波磁束の周囲に誘導
電流が生じ、その環状の電流路の内、加温を必要
とする部分以外の電流路はパツドが形成する。し
かしパツドのない部分では誘導電流が生体（患
部）を流れてそこを加温する。(Operation) A high-frequency current is supplied from the high-frequency generator to the coil, and high-frequency magnetic flux is generated toward the space in which the living body is placed. As a result, an induced current is generated around the high-frequency magnetic flux, and the pad forms the current path other than the portion that requires heating among the annular current paths. However, in areas without pads, induced current flows through the living body (affected area) and warms it.
（実施例）
以下、図面を参照して本発明の実施例を詳細に
説明する。(Example) Hereinafter, an example of the present invention will be described in detail with reference to the drawings.
第１図は本発明の一実施例の模式的構成図であ
る。図において、第４図と同等の部分には同じ符
号を付してある。図中、５は胴体２の周辺部にあ
る癌等の悪性腫瘍が発生している患部、６は胴体
２等の生体組織よりも電気伝導度の高い液体（例
えば生理食塩水）を満たしたパツドで、患部５を
残して胴体２の周囲を覆つている。 FIG. 1 is a schematic diagram of an embodiment of the present invention. In the figure, parts equivalent to those in FIG. 4 are given the same reference numerals. In the figure, 5 is an affected area around the torso 2 where a malignant tumor such as cancer has occurred, and 6 is a pad filled with a liquid (e.g. physiological saline) that has higher electrical conductivity than the living tissue of the torso 2 etc. The area around the torso 2 is covered, leaving the affected area 5.
次に、上記のように構成された実施例の動作を
説明する。高周波発生器３で発生した高周波信号
を1Tコイル１に供給する。1Tコイル１は入力高
周波信号によつて目的とする胴体２の断面付近で
は紙面に垂直な方向の高周波磁界を発生する。こ
の高周波磁界に直交する面内に誘導電流４が発生
するが、この誘導電流は表皮効果により主として
導電体の周辺部を流れることになり、胴体２の周
囲を覆つているパツド６と、パツド６の無い部分
である患部５に誘導電流４が流れる。従つて、胴
体２の生体組織では、患部５とその周辺にのみ誘
導電流４が流れ、患部５を加温するが、胴体２の
他の健全な加温の必要のない部分を加温すること
はない。 Next, the operation of the embodiment configured as described above will be explained. The high frequency signal generated by the high frequency generator 3 is supplied to the 1T coil 1. The 1T coil 1 generates a high-frequency magnetic field in a direction perpendicular to the plane of the paper in the vicinity of the target cross-section of the fuselage 2 according to the input high-frequency signal. An induced current 4 is generated in a plane perpendicular to this high-frequency magnetic field, but this induced current mainly flows around the periphery of the conductor due to the skin effect, and the pad 6 surrounding the body 2 and the pad 6 An induced current 4 flows through the affected area 5, which is the area without the . Therefore, in the living tissue of the torso 2, the induced current 4 flows only in the affected area 5 and its surroundings, warming the affected area 5, but heating other parts of the torso 2 that do not require healthy heating. There isn't.
次に、他の実施例として核磁気共鳴断層撮影装
置の高周波磁界印加のためのバードケージコイル
を利用するハイパーサーミア装置について説明す
る。第２図はバードケージコイルをアプリケータ
として高周波磁界を印加したときに発生する誘導
電流を示す図である。図において、第１図と同等
な部分には同一の符号を付してある。バードケー
ジコイル１１によつて発生する高周波磁界１２
は、図示のように胴体２を横断する方向に発生
し、高周波磁界１２に垂直な面内にループ状に誘
導電流４を発生する。この誘導電流は図示の胴体
２の断面上では紙面に垂直に左右逆向の方向に流
れている。従つて誘導電流が胴体２の左右両周辺
部を加温している。 Next, as another embodiment, a hyperthermia device using a birdcage coil for applying a high frequency magnetic field of a nuclear magnetic resonance tomography device will be described. FIG. 2 is a diagram showing an induced current generated when a high frequency magnetic field is applied using a birdcage coil as an applicator. In the figure, parts equivalent to those in FIG. 1 are given the same reference numerals. High frequency magnetic field 12 generated by birdcage coil 11
is generated in a direction across the fuselage 2 as shown, and generates an induced current 4 in a loop shape in a plane perpendicular to the high frequency magnetic field 12. On the illustrated cross section of the body 2, this induced current flows in opposite directions, perpendicular to the plane of the paper. Therefore, the induced current heats both the left and right peripheral portions of the body 2.
第３図は本発明のバードケージコイルをアプリ
ケータとして用いたハイパーサミア装置の他の実
施例の模式的構成図である。図において、第２図
は同等の部分には同一の符号を付してある。図
中、１３は第１図のハイパーサーミア装置に用い
たパツド６と同様な導電率の高い液体を満たした
パツドで、パツド６とは異なり断面積は小さくて
よい。パツド１３を胴体２の誘導電流４の流れる
部分の患部の無い片側に取り付けたので、図の右
側の誘導電流４の断面はパツド１３内を流れ、左
側部分に示す誘導電流４のみが胴体２中を流れ
て、左側胴体中に存在する患部を加温する。 FIG. 3 is a schematic diagram of another embodiment of a hypersamia device using the birdcage coil of the present invention as an applicator. In the figures, the same parts in FIG. 2 are given the same reference numerals. In the figure, numeral 13 is a pad filled with a highly conductive liquid similar to the pad 6 used in the hyperthermia device of FIG. 1, and unlike the pad 6, the cross-sectional area may be small. Since the pad 13 is attached to one side of the body 2 where the induced current 4 flows through which there is no affected area, the cross section of the induced current 4 on the right side of the figure flows inside the pad 13, and only the induced current 4 shown on the left side flows through the body 2. Flows through the air to warm the affected area on the left side of the torso.
以上、説明したようにパツドを加温の必要のな
い部分に取り付けることにより、患部のみを加温
することができるようになり、従来、誘電加温法
に比べて被検体に全く接触することなく加温する
ことができる利点を有しているが、局所加温がで
きなかつた誘導加温法を、局所加温が可能な方法
にすることができるようになつた。 As explained above, by attaching the pad to an area that does not need heating, it is now possible to heat only the affected area, without having to come into contact with the subject at all compared to conventional dielectric heating methods. Although the induction heating method has the advantage of being able to heat the body, it is now possible to convert it to a method that allows local heating.
（発明の効果）
以上詳細に説明したように、本発明によれば、
局所的に加温することのできる高周波誘導加温法
によるハイパーサーミア装置を実現することがで
きて、実用上の効果は大きい。(Effects of the Invention) As explained in detail above, according to the present invention,
It is possible to realize a hyperthermia device using a high-frequency induction heating method that can locally heat the device, which has great practical effects.
第１図は本発明の一実施例の模式的構成図、第
２図はバードケージコイルをハイパーサーミア装
置のアプリケータに利用する場合の図、第３図は
バードケージコイルを利用した本発明の他の実施
例の図、第４図は従来の高周波誘導法によるハイ
パーサーミア装置の説明図である。
１……1Tコイル、２……胴体、３……高周波
発生器、４……誘導電流、５……患部、６，１３
……パツド、１１……バードケージコイル、１２
……高周波磁界。
FIG. 1 is a schematic diagram of an embodiment of the present invention, FIG. 2 is a diagram showing a case where a birdcage coil is used as an applicator of a hyperthermia device, and FIG. 3 is a diagram showing an example of the present invention using a birdcage coil. FIG. 4 is an explanatory diagram of a hyperthermia device using a conventional high-frequency induction method. 1... 1T coil, 2... Body, 3... High frequency generator, 4... Induced current, 5... Affected area, 6,13
...Putsudo, 11...Birdcage Coil, 12
...High frequency magnetic field.
Claims (1)
て患部を加温する高周波誘導加温法によるハイパ
ーサーミア装置において、 高周波電流を発生する高周波発生器と、 該高周波発生器の出力する高周波電流が供給さ
れ、生体が載置される空間に向けて高周波磁束を
発生するコイルと、 生体組織より電気伝導度の高い液体が内部に充
満され、前記コイルによる高周波磁束の周囲に生
じる誘導電流の環状の電流路の内、加温を必要と
する部分以外の電流路を形成するパツドと を有することを特徴とするハイパーサーミア装
置。[Claims] 1. A hyperthermia device using a high-frequency induction heating method that heats an affected area using an induced current generated by a high-frequency magnetic field, comprising: a high-frequency generator that generates a high-frequency current; and an output of the high-frequency generator. A coil is supplied with a high-frequency current to generate high-frequency magnetic flux toward the space where the living body is placed, and the inside is filled with a liquid that has higher electrical conductivity than the living tissue, and the induction generated around the high-frequency magnetic flux by the coil is filled with a liquid that has higher electrical conductivity than the living tissue. 1. A hyperthermia device comprising a pad that forms a current path other than a portion that requires heating among a circular current path.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP27109887A JPH01113076A (en) | 1987-10-27 | 1987-10-27 | Hyperthermia apparatus |
| PCT/JP1988/001093 WO1989003706A1 (en) | 1987-10-27 | 1988-10-27 | Hyperthermic apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP27109887A JPH01113076A (en) | 1987-10-27 | 1987-10-27 | Hyperthermia apparatus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH01113076A JPH01113076A (en) | 1989-05-01 |
| JPH0371909B2 true JPH0371909B2 (en) | 1991-11-14 |
Family
ID=17495325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP27109887A Granted JPH01113076A (en) | 1987-10-27 | 1987-10-27 | Hyperthermia apparatus |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JPH01113076A (en) |
| WO (1) | WO1989003706A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0474984A3 (en) * | 1990-09-10 | 1992-06-10 | Omron Corporation | Hyperthermia device |
| JP6143712B2 (en) * | 2014-06-13 | 2017-06-07 | 株式会社日立製作所 | Railway vehicle with multiple underfloor equipment |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62197073A (en) * | 1986-02-24 | 1987-08-31 | 株式会社東芝 | Hyperthermia apparatus |
| JPS63156618U (en) * | 1987-03-31 | 1988-10-14 |
-
1987
- 1987-10-27 JP JP27109887A patent/JPH01113076A/en active Granted
-
1988
- 1988-10-27 WO PCT/JP1988/001093 patent/WO1989003706A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH01113076A (en) | 1989-05-01 |
| WO1989003706A1 (en) | 1989-05-05 |
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