JPH0370A - Blood circuit for circulation outside body - Google Patents

Abstract

PURPOSE:To prevent the occurrence of residence to blood and to prevent the occurrence of a thrombus by a method wherein a pressure gauge with a liquid connection mechanism is connected to a branch pipe, and a blood coagulation preventing liquid introducing means is mounted in the branch pipe between the pressure gauge with a liquid connection mechanism and a blood sampling means. CONSTITUTION:3-way stop cocks 23 are located in branch pipes 21 and 22, and a liquid connection type pressure gauge 24 is connected to the tip of each branch pipe. The 3-way stop cock 23 is connected to each of the branch pipes 21 and 23, and a blood coagulation preventing liquid feed source 32 is connected between the liquid connection type pressure gauges 24 through a blood coagulation preventing liquid feed pipe 31 branched through a 3-way stop cook 33. Blood coagulation preventing liquid is caused to flow in fourth and fifth pipings 8 and 11 from the blood coagulation preventing liquid feed source 32 through a blood coagulation preventing liquid feed pipe 31, the 3-way stopcock 33, the branch pipe 21 or 22, and the 3-way stop cock 23. In this case, since blood coagulation preventing liquid flows through the branch pipes 21 and 22 and the blood coagulation preventing liquid feed pipe 31, blood is prevented from residence.

Description

DETAILED DESCRIPTION OF THE INVENTION "Field of Industrial Application" The present invention relates to an extracorporeal circulation blood circuit that can prevent blood clots.

"Prior Art" As is well known, in a conventional extracorporeal circulation blood circuit, as shown in FIG. 5, a reservoir 3 is connected to a first pipe 2 connected to a patient's blood outlet 1. This reservoir 3 has a second
A blood pump 5 is connected to the blood pump 5 via a third pipe 4, and a heat exchanger 7 is connected to the blood pump 5 via a third pipe 6.
An oxygenator 9 is connected to the heat exchanger 7 via a fourth pipe 8, and this oxygenator 9 is connected to a fifth pipe 11 connected to the patient's blood return port IO. This removes oxygen and carbon dioxide from the patient's blood.

Note that the first pipe 2. Second piping 4. Third piping 6, fourth piping 8. The fifth pipe 11 constitutes a main pipe.

However, it is necessary to check in what condition the blood taken from the patient flows into the oxygenator 9 and whether the blood is given the required amount of oxygen in the oxygenator 9 and returned to the patient. Become. For this reason, branch pipe 1 from the main pipe
The syringe 18 attached to these three-way stopcocks 16 and 17 by opening the three-way stopcocks 16 and 17 interposed in 2.14.
．． 19, blood sampling is periodically performed at the blood inlet or outlet of the artificial lung 9 to confirm the condition of the blood.

Note that the pressure gauge 13 is connected to the fourth pipe 8, and the fifth
A pressure gauge 15 is connected to the pipe 11 so that the blood pressure at the blood inlet and outlet of the artificial lung 9 can be checked.

The purpose of these pressure measurements is to measure the pressure at the oxygenator blood inlet in order to know when to replace the oxygenator due to an abnormality in the oxygenator. For example, due to thrombus formation, the effective area decreases and the pressure increases, causing gas exchange. In order to detect an artificial lung whose capacity has decreased,
In the case of measuring the pressure at the outlet of the oxygenator, the purpose is to know if there is any trouble between the outlet of the oxygenator and the cannula connected to the patient (particularly the occurrence of blood clots in this area).

"Problem to be Solved by the Invention" However, in such a conventional extracorporeal circulation blood circuit, the branch pipe 12.14 and the pressure gauge 1315 portion, that is,
Blood stagnation occurs in the blood sampling line and pressure measurement line.
There was a problem in that blood clots were likely to form in areas where blood remained.

The present invention has been made in view of the above-mentioned circumstances, and an object of the present invention is to provide an m1ff1 circuit for extracorporeal circulation that can prevent stagnation of blood and prevent the occurrence of blood clots.

"Means for Solving the Problems" The present invention has the following configuration in order to achieve the above object. That is, in the invention according to claim 1, from the blood extraction port side, the main pipe is connected to the blood pump, the heat exchanger 1, the oxygenator, and the blood extraction port and the white liquid return port in order, and from this main pipe An extracorporeal circulation blood circuit comprising a blood collection means for collecting blood through a branched branch pipe, and a pressure gauge for measuring the pressure of blood flowing in the main pipe,
A pressure gauge with a liquid contact mechanism is connected to the branch pipe, and a blood coagulation prevention liquid introducing means is provided in the branch pipe between the pressure gauge with a liquid contact mechanism and the blood sampling means.

In addition, in the invention according to claim 2, a main pipe is connected to the blood take-out port and the blood return port in order from the blood take-out port side through a blood pump, a heat exchanger 1 and an oxygenator, and a main pipe is branched from this main pipe. In the extracorporeal circulation blood circuit, the branch pipe is provided with a blood sampling means for collecting blood through a branch pipe, and a pressure gauge for measuring the pressure of blood flowing in the main pipe, wherein the branch pipe is connected to the oxygenator and the blood sample. It consists of a bypass passage communicating with the outlet, a pressure regulator is interposed in the bypass passage, a pressure gauge is connected to the pressure regulator, and a blood coagulation prevention liquid introducing means is provided in the branch pipe.

"Function" According to the invention described in claim 1, blood does not stagnate by continuously introducing the blood coagulation prevention liquid into the branch pipe branched from the main pipe by the blood coagulation prevention liquid introduction means.
The occurrence of blood clots is prevented, and even if a blood clot occurs in the oxygenator or the downstream side of the oxygenator, a pressure gauge with a liquid contact mechanism installed in the branch pipe will detect the increase in blood pressure, and the oxygenator or blood Informs you that it is time to replace the circuit.

Further, according to the invention as set forth in claim 2, by continuously introducing the blood coagulation prevention liquid into the branch pipe branched from the main pipe by the blood coagulation prevention liquid introducing means, blood does not stagnate and blood clots are formed. Even if a blood clot occurs in the oxygenator or the downstream side of the oxygenator, the constant pressure regulator installed in the branch pipe automatically bypasses the blood to the blood outlet and removes this blood. By bypassing the oxygenator, it is possible to know that it is time to replace the oxygenator.

"Embodiment" Hereinafter, a first embodiment of the present invention will be described based on FIGS. 1 and 2. In this embodiment, the same parts as in the conventional example are given the same reference numerals, and the explanation thereof will be omitted. In this embodiment, a branch pipe 21.22 is provided instead of the branch pipe 12.14 of the prior art.

The branch pipes 21 and 22 each have a conventional three-way stopcock 16.
, 17, a three-way stopcock 23 is interposed.

A liquid chamber 24c of a pressure gauge with a liquid contact mechanism (hereinafter referred to as a liquid contact type pressure gauge) 24 is connected to the tips of the branch pipes 21 and 22, respectively.

This pressure gauge 24 with a liquid contact mechanism consists of a liquid contact mechanism 24a, a connecting line 25, and a pressure gauge 26. The inside of the liquid contact mechanism 24a is divided by a diaphragm 24b into a liquid chamber 24c and a pressure sensor 24d. A three-way stopcock 24e for venting air when filling heparinized saline into the liquid chamber 24c is connected to the pressure sensor 24d, and a pressure gauge 26 is connected to the pressure sensor 24d via a connecting line 25.

A three-way stopcock 27 is connected to the - connection port 23a of the three-way stopcock 23. A syringe 29 is connected to the - connection port 27a of the three-way stopcock 27, and a syringe 29 is connected to the - connection port 27a of the three-way stopcock 27.
A syringe 3o is connected to b. Three-way stopcock 23,
27. A blood sampling means is constituted by a syringe 29°30 and the like.

In addition, blood is supplied to the branch pipes 21 and 22 through a blood coagulation prevention liquid supply pipe 31 which is branched from the branch pipe 21 or 22 via the three-way stopcock 33 between the three-way stopcock 23 and the wetted type pressure gauge 24. An anticoagulation liquid supply source (infusion bag, syringe, etc.) 32 is connected. Blood coagulation prevention liquid supply source 32 The blood coagulation prevention liquid supply pipe 31 constitutes blood coagulation prevention liquid introducing means.

When the extracorporeal circulation blood circuit of this embodiment is used, normally the three-way stopcock 23 is in communication with the branch pipe 21 and the three-way stopcock 33, and the branch pipe 22 and the three-way stopcock 33 are connected, respectively.
Branch pipe 21 and three-way stopcock 27, branch pipe 22 and three-way stopcock 27
and the three-way stopcock 33 is in a state where the three-way stopcock 23 and the anti-blood coagulation liquid supply pipe 31 are in communication with each other, and the liquid chamber 24
c and the anticoagulation liquid supply pipe 31 or the branch pipe 21. The liquid chamber 24c, the blood coagulation prevention liquid supply pipe 31 are all in communication, and the branch pipe 22. The liquid chamber 24c and the blood coagulation prevention liquid supply pipe 31 are all in communication (in this state, continuous pressure measurement and coagulation prevention can be performed at the same time),
Furthermore, the three-way stopcock 27 is set in such a state that the three-way stopcock 23 and the syringe 30 communicate with each other, and the connection port 27a and the connection port 27b do not communicate with each other, and the fourth piping 8. A blood coagulation preventive liquid, for example, heparinized saline, is supplied into the fifth pipe 11 from a blood coagulation preventive liquid supply source 32 through a blood coagulation preventive liquid supply pipe 31°, a three-way stopcock 332, a branch pipe 21, or a branch pipe 22. The water is allowed to gradually and continuously flow in through the three-way stopcock 23. In this case, branch pipes 21, 22 . The heparinized saline flows in the blood coagulation prevention liquid supply pipe 31 as well, which prevents blood from stagnation, and in the wetted type pressure gauge 24, the heparinized saline flowing into the liquid chamber 24c and the pressure sensor 24d and is separated by a diaphragm 24b.

In addition, when sampling the blood in the extracorporeal circulation blood circuit at the inlet and outlet of the m liquid of the artificial lung 9, the anticoagulation liquid supply pipe 31 is supplied by the anticoagulation liquid supply source 32.
The supply of heparinized saline to the interior of the fourth stop was stopped, and the three-way stopcock 23 was removed because the three-way stopcock 33 and the three-way stopcock 27 were not communicating with each other. The 5' piping 8, 11 and the three-way stopcock 27 are switched to a state in which they are in communication, the three-way stopcock 27 is switched to a state in which the three-way stopcock 23 and the syringe 29 are in communication, and the three-way stopcock 23 and the syringe 3° are not in communication. . After all the blood diluted with heparinized saline is sucked out by the syringe 29, the three-way stopcock 27 is brought into communication with the three-way stopcock 23 and the syringe 3o, and the syringe 30 and the syringe 29
The blood is collected using the syringe 30. In this case, the fourth pipe 8. The blood in the fifth pipe ll is transferred to the branch pipe 21 or the branch pipe 22. Three-way stopcock 23,2
7. Flows into the syringe 30 through the connection port 27b, branch pipe 211 between the three-way stopcocks 23 and 33, branch pipe 22° blood coagulation prevention liquid supply pipe 31. Since heparin-added saline flows into the liquid chamber 24c of the wetted type pressure gauge 24, there is no place where blood will stagnate and coagulate (thrombus formation is prevented).

Therefore, according to this embodiment, blood will not stagnate and thrombi will not occur either in normal times or during blood sampling.
The blood pressure at the inlet or outlet of blood is displayed, and if a thrombus occurs in the extracorporeal circulation blood circuit, the pressure exceeds the limit and the occurrence of a thrombus is recognized.The displayed pressure is used to confirm the normal state of the extracorporeal circulation blood circuit. It also serves as a guide for when to replace the oxygenator 9.

In the above example, heparin-added physiological saline was used as the blood coagulation prevention liquid, but the present invention is not limited to this, and it does not affect the medical condition of the patient to whom the extracorporeal circulation blood circuit of this example is applied. In some cases, non-heparinized physiological saline may be used as long as it can prevent blood coagulation.

Further, the branch pipe 21 in the above embodiment. Branch pipe 22, three-way stopcock 23, 27, 33. The piping routes for the syringes 29, 30, etc. are an example for carrying out the present invention, and these routes can be modified in various ways without departing from the spirit of the present invention.

Next, a second embodiment of the present invention will be described based on FIG. A reservoir 43 is connected to a first pipe 42 connected to a patient's blood extraction port 41, a liquid pump 45 is connected to the reservoir 43 via a second pipe 44, and a third blood pump 45 is connected to the reservoir 43 via a second pipe 44. Heat exchanger 47 via piping 46
is connected, an oxygenator 49 is connected to the heat exchanger 47 via a fourth pipe 48, and this oxygenator 49 is connected to a fifth pipe 51 connected to a blood return port 50 of the patient. , oxygen is added to the patient's blood and carbon dioxide is removed by an artificial lung 49. Note that the first pipe 42. Second piping 44.
Third piping 46. Fourth piping 48. The fifth pipe 51 constitutes a main pipe.

Further, a first branch pipe (first bypass circuit) 52 from the main pipe is provided between the first pipe 42 and the fourth pipe 48 near the oxygenator blood population, and the first pipe 42 and the fourth pipe 48 are connected to each other. A second pipe from the main pipe is connected between the pipe 51 of No. 5 and the part near the oxygenator fluid outlet.
A branch pipe (second bypass circuit) 53 is provided.

A pressure regulator 54 is interposed in the first branch pipe 52 and communicated with a liquid chamber 54c which will be described later, and a pressure regulator 55 is interposed in the second branch pipe 53 and communicated with a liquid chamber 55c which will be described later.

The pressure regulator 54 has a main body 54a partitioned by a diaphragm 54b into a liquid chamber 54c and an air chamber 54d.
A pressure gauge 54f is connected to d via a pipe 54e, and a syringe 54h is further connected to a branch pipe provided in the pipe 54e via a cock 54g. The pressure regulator 54 is
Blood or heparinized saline is passed through the liquid chamber 54C, air at a predetermined pressure is filled from the syringe 54h into the air chamber 54d, and the fluid pressure within the first branch pipe 52 is increased to the air chamber 54.
If the air pressure is lower than the air pressure in the first branch pipe 54C, the diaphragm 54b blocks the flow of fluid in the branch pipe 52 in the liquid chamber 54C, and if the fluid pressure in the first branch pipe 52 is higher than the air pressure in the air chamber 54d. The fluid in the branch pipe 52 flows through the liquid chamber 54c, and the fluid pressure flowing through the liquid chamber 54c is always kept at a constant pressure. In addition, the constant pressure regulator 55
consists of a main body 55a, a diaphragm 55b in the main body 55a, a liquid chamber 55C, an air chamber 55d, a pipe 55e, a pressure gauge 55f, a cock 54g, and a syringe 55h, and has the same configuration as the pressure regulator 54, so a description thereof will be omitted.

A feeding means 56 is interposed on the oxygenator 49 side between the pressure regulator 54 of the branch pipe 52 and the fourth pipe 48 near the artificial lung surface, and a blood coagulation prevention liquid is provided on the pressure regulator 54 side. A blood coagulation prevention fluid supply source (infusion bag, syringe, etc.) 58 is interposed via a supply pipe 57 .

The blood sampling means 56 is a three-way stopcock 59 interposed in the branch pipe 52.
The three-way stopcock 60 is connected to the three-way stopcock 59, and the syringes 61 and 62 are connected to the three-way stopcock 60.

In addition, the first pipe 42 of the branch pipe 52. A blood coagulation prevention liquid supply source (infusion bag, syringe, etc.) 64 is interposed between the two constant pressure blades 54 via a blood coagulation prevention liquid supply pipe 63 .

On the other hand, a blood sampling means 65 is interposed on the oxygenator 49 side between the pressure regulator 55 of the branch pipe 53 and the vicinity of the oxygenator blood outlet of the fifth pipe 51, and a blood coagulation prevention liquid is supplied to the pressure regulator 55 side. A blood coagulation prevention fluid supply source (infusion bag, syringe, etc.) 67 is interposed through the tube 66 .

The blood sampling means 65 is a three-way stopcock 68 interposed in the branch pipe 53.
It consists of a three-way stopcock 69 connected to this three-way stopcock 68, and a syringe 70, 71 connected to this three-way stopcock 69, and has the same configuration as the blood sampling means 56.

On the other hand, a blood sampling means 72 is interposed between the first pipe 42 of the branch pipe 53 and the pressure regulator 55 on the first pipe 42 side, and a blood sampling means 72 is interposed on the pressure regulator 55 side via a blood coagulation prevention liquid supply pipe 73. A blood anticoagulation fluid supply source (infusion bag, syringe, etc.) 74 is interposed.

The blood sampling means 72 is a three-way stopcock 75 interposed in the branch pipe 53.
It consists of a three-way stopcock 76 connected to the three-way stopcock 75, and a syringe 77.78 connected to the three-way stopcock 76, and has the same configuration as the blood sampling means 56.65.

In addition, the blood coagulation prevention liquid supply pipe 57 and blood coagulation prevention liquid supply source 58, the blood coagulation prevention liquid supply pipe 63 and blood coagulation prevention liquid supply #64, and the blood coagulation prevention liquid supply pipe 66 and blood coagulation prevention liquid supply f! A87, the blood anticoagulation liquid supply pipe 73 and the blood anticoagulation liquid supply source 74 constitute a white liquid anticoagulation liquid introducing means.

When using the extracorporeal circulation blood circuit of this embodiment,
The internal pressure of the air chambers 54d and 55d of the pressure regulator 54.55 is set to a predetermined pressure, and the three-way stopcock 59.68.75 is normally turned on.
The first branch pipe 52 and the second branch pipe 53 are in an open state, and the first branch pipe 52 and the three-way stopcock 60 do not communicate with each other, and the second branch pipe 53 and the three-way stopcock 69 and the second branch pipe 53 and the three-way stopcock do not communicate with each other. 76, and the first branch pipe 52. Second
Inside the branch pipe 53, a blood coagulation prevention liquid supply source 5B,
64, 67. Blood clotting prevention liquid supply pipe 57, 63 from 74
, 66, 73, for example, heparinized saline is gradually and continuously introduced.

Then, this heparinized saline solution is maintained at a constant pressure if the oxygenator 49 and the blood flow between the oxygenator 49 and the blood return port 5o are normal, that is, if there is no accumulation of blood or thrombus in the circuit. Although the blood flows into the pressure regulators 54, 55 due to the action of the pressure regulators 54, 55, it does not flow through these pressure regulators 54, 55, but mixes with blood and flows in the other direction, thereby preventing blood stagnation and thrombus formation.

In the event that blood stagnates or a blood clot occurs in the oxygenator 49, the blood pressure at the blood inlet of the oxygenator 49 will rise, causing the second oxygenator 4
The blood of 9 blood flows through the first branch pipe 52 and the constant pressure regulator 54 to the first pipe 42 .

This first branch pipe 52. It is recognized that the oxygenator 49 has reached the time for replacement due to blood flowing through the constant pressure device 54. Note that if the pressure regulator 54 is configured to emit sound or light when blood flows, the sound or light emitted at such times can be used as an alarm to prevent thrombus occurrence.

In addition, if blood stagnation or a thrombus occurs between the oxygenator 49 and the blood return port 50 (thrombus is likely to occur at the cannula insertion part of the blood return port 50), the blood pressure on the blood outlet side of the oxygenator 49 rises, and the blood on the blood outlet side of the oxygenator 49 flows into the branch pipe 53. It flows through the constant pressure regulator 55 to the first pipe 42 . As blood flows through the second branch pipe 53 and the pressure regulator 55, it is notified that blood has accumulated or a thrombus has occurred between the oxygenator 49 and the blood return port 50.

Note that if the pressure regulator 55 is configured to emit a sound or light when blood flows, the sound or light emission at such times can be used as an alarm to prevent the occurrence of blood clots. It is similar to

In addition, when blood in the extracorporeal circulation blood circuit is sampled at the blood inlet of the artificial lung 49, heparinized saline is supplied into the blood anticoagulation liquid supply pipe 57 by the blood anticoagulation liquid supply source 58. Stop the three-way stopcock 59
The three-way stopcock 60 is switched to a state in which the three-way stopcock 59 and the syringe 61 are in communication and the five three-way stopcocks and the syringe 62 are not in communication. After all the blood diluted with the heparinized saline is sucked out by the syringe 61, the three-way stopcock 60 is brought into communication with the three-way stopcock 59 and the syringe 62, and the five three-way stopcocks are not in communication with the syringe 61. Then, venous blood is collected using the syringe 62. In this case, the blood in the fourth pipe 48 flows into the syringe 62 through the branch pipe 52 and the three-way stopcock 59.60. Since the heparinized saline flows between the first pipes 42, there is no place where blood stagnates and coagulates, and the formation of thrombus is prevented.

In addition, when sampling the blood in the extracorporeal circulation blood circuit at the blood outlet of the artificial node 49, the blood anticoagulation liquid supply pipe 6 by the blood anticoagulation liquid supply 21i%67
The supply of heparinized saline into B9 is stopped, the three-way stopcock 68 is brought into communication with the three-way stopcock 69, and the three-way stopcock B9 is switched to a state where it is not communicated with the pressure regulator 55, and the three-way stopcock B9 is brought into communication with the three-way stopcock 68 and the syringe 70. Then, the three-way stopcock 68 and the syringe 71 are switched to a state where they do not communicate with each other. And syringe 70
After sucking out all the blood diluted with heparinized saline, the three-way stopcock 69 is replaced with the three-way stopcock 68.
and the syringe 71 communicate, and the three-way stopcock 68 and the syringe 7
0, and arterial blood is collected using the syringe 71. In this case, the blood in the fifth pipe 51 passes through the branch pipe 53 and three-way stopcocks 68 and 69 to the syringe 71.
into the three-way stopcock 68. Since the heparinized saline flows between the first pipes 42, there is no place where blood stagnates and coagulates, and the formation of thrombus is prevented. It should be noted that blood can be collected in the blood collecting means 72 in the same manner as in the other blood collecting means 56 and 65.

Note that blood collection in the arterial direction is performed only by the blood collection means 65, but venous blood collection is performed using the blood collection means 58, 72 or the first branch pipe 52 between the blood anticoagulation liquid supply pipe 63 and the first pipe 42. 56 It is also possible to provide a similar blood sampling means, that is, any one of these three blood sampling means can be used.
You can do it in several places.

Therefore, according to this embodiment, blood does not stagnate and thrombus does not occur either in normal times or during [fu liquid sampling].

In the second embodiment shown in FIG. 3, the pressure regulator 54 and the first pipe 42 are connected by a first branch pipe 52, and the first branch pipe 52 is connected to a blood coagulation prevention liquid supply pipe 63. The anticoagulation liquid supply source 64 is communicated with the constant pressure regulator 54 and the fourth
The first branch pipe 52 connects the pipe 48 of the
A blood sampling means 56 is inserted into the branch pipe S2, and an anticoagulation liquid supply pipe 57. The blood coagulation prevention liquid supply source 58 is communicated with the constant pressure device 55 and the first pipe 42 through the second branch pipe 53.
The blood sampling means 72 is connected to the second branch pipe 53, and the anticoagulation liquid supply pipe 73. Although the blood coagulation prevention liquid supply source 74 is communicated with, for example, as shown in FIG.
Piping 42. The first branch pipe 52 between the pressure regulators 54 and the anticoagulation liquid supply pipe 63. The blood coagulation prevention liquid supply source 64 and the blood sampling means 5B are omitted, and the pressure regulator 55 of the second branch pipe 53 is used. The part between the blood coagulation prevention liquid supply pipe 73 and the liquid chamber 54c of the constant pressure regulator 54
A third branch pipe (third bypass circuit) 81 branched from the second branch pipe 53 may be used to communicate the blood with the second branch pipe 53, and venous blood may be collected only from the blood collection means 72.

Therefore, according to this embodiment, blood does not stagnate and thrombus does not occur either in normal times or during blood sampling (the third embodiment).

Note that the first branch pipe 52 in the second embodiment shown in FIG. Second branch pipe 53. Three-way stopcock 59°60.68.6
9,75.76, Syringe 61゜82.70,71
, 77, 78, etc., and the first branch pipe 52° and second branch pipe 53. in the third embodiment shown in FIG. The piping routes such as the third branch pipe 81 are an example for implementing the present invention, and these routes can be modified in various ways without departing from the spirit of the present invention.

"Effects of the Invention" According to the invention as claimed in claim 1, the main piping is connected to the blood extraction port and the blood return port in order from the blood extraction port side through the blood pump, the heat exchanger 2, and the oxygenator. In an extracorporeal circulation blood circuit comprising a blood sampling means for collecting blood through a branch pipe branched from the main pipe, and a pressure gauge for measuring the pressure of blood flowing in the main pipe, a mechanism in contact with the branch pipe. In addition to connecting a pressure gauge with a contact mechanism, a means for introducing a blood coagulation prevention liquid is provided in the branch pipe between the pressure gauge with a liquid contact mechanism and the blood sampling means. blood population,
Of course, it is possible to check the blood pressure at the outlet and to check the blood condition by collecting blood using a blood sampling device.
The anticoagulant liquid can be continuously introduced into the branch pipe branched from the main pipe by the anticoagulant introducing means, thereby preventing blood from stagnation and causing thrombus. can be prevented. Additionally, in the unlikely event that a blood clot occurs in the oxygenator or the downstream side of the oxygenator, a pressure gauge with a wetted mechanism installed in the branch pipe will detect an increase in blood pressure and indicate that it is time to replace the oxygenator. I can let you know.

Further, according to the invention set forth in claim 2, the blood pump, the heat exchanger 1 and the oxygenator are interposed in order from the blood extraction port side, and the +m
A main pipe connected to a liquid extraction port and a blood return port, a blood sampling means for collecting blood through a branch pipe branched from the main pipe, and a pressure gauge for measuring the pressure of blood flowing through the main pipe. In the night circuit (for extracorporeal circulation), the branch pipe includes a bypass passage that communicates the oxygenator with the blood extraction port, a pressure regulator is interposed in the bypass passage, and a pressure gauge is connected to the pressure regulator. In addition, since the branch pipe is provided with a blood coagulation prevention liquid introduction means, the blood coagulation prevention liquid is continuously introduced into the branch pipe branched from the main pipe by the blood coagulation prevention liquid introduction means. Blood does not stagnate and the occurrence of thrombus can be prevented.

In addition, even if a blood clot occurs in the oxygenator or downstream of the oxygenator, the pressure regulator installed in the branch pipe can automatically bypass the blood to the blood outlet, making it extremely safe. The phenomenon of blood bypass can inform the user that it is time to replace the artificial lung, which is extremely effective in use.

[Brief explanation of the drawing]

1 and 2 show a first embodiment of the present invention,
Figure 1 is a piping diagram of the main parts, Figure 2 is a schematic piping diagram, Figure 3 is a schematic piping diagram showing a second embodiment of the present invention, and Figure 4 is a diagram showing a third embodiment of the present invention. Schematic piping diagram, Fig. 5 is a schematic piping diagram of a conventional blood circuit for extracorporeal circulation. 1.41... Outlet port, 5, 45... Blood pump, 7.47. ...Heat exchanger, 9,49
......Artificial lung, 10.50...Blood return port, 21.22...Branch pipe, 23.27.33
... Three-way stopcock, 24 ... Pressure gauge with liquid contact mechanism (wetted type pressure gauge), 26 ... Pressure gauge, 29.30, 61.62, 70. 71.77.78・
...Syringe, 31.57, 63.6673...
...Blood coagulation prevention liquid supply pipe, 32.58, 64.6
7.74... Blood clotting prevention fluid supply source, 52...
...First branch pipe (first bypass circuit) 53...
・・Second branch pipe (second bypass circuit), 54.55・・
... Pressure regulator, 54 ... Pressure gauge, 56, 65
．． 72... Blood sampling means, 81... Third branch pipe (third bypass circuit).

Claims (2)

[Claims] (1) Blood is collected sequentially from the blood extraction port side through a main piping that is connected to the blood extraction port and blood return port via a blood pump, a heat exchanger, and an oxygenator, and a branch pipe that branches off from this main piping. In the extracorporeal circulation blood circuit, the blood circuit includes a blood sampling means for measuring blood flowing through the main pipe, and a pressure gauge for measuring the pressure of blood flowing in the main pipe, wherein a pressure gauge with a liquid contacting mechanism is connected to the branch pipe, and the liquid contacting mechanism is connected to the branch pipe. A blood circuit for extracorporeal circulation, characterized in that an anticoagulation liquid introduction means is provided in the branch pipe between the attached pressure gauge and the blood sampling means. (2) Blood is collected sequentially from the blood extraction port side through a main pipe connected to the blood extraction port and blood return port via a blood pump, a heat exchanger, and an oxygenator, and a branch pipe branched from this main pipe. In the extracorporeal circulation blood circuit, the branch pipe includes a blood sampling means for collecting blood, and a pressure gauge for measuring the pressure of blood flowing in the main pipe, wherein the branch pipe is connected to a bypass passage communicating with the oxygenator and the blood extraction port. A blood circuit for extracorporeal circulation, characterized in that a pressure regulator is interposed in the bypass passage, a pressure gauge is connected to the pressure regulator, and an anticoagulation liquid introducing means is provided in the branch pipe.