JPH0356069B2 - - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION (Field of Industrial Application) The present invention relates to a method for generating a low frequency electrical stimulation signal for applying electrical stimulation to a living body.

(Prior art) Traditionally, when a living body is given auditory stimulation by listening to classical music or favorite music, it feels pleasure or displeasure based on experiential ideas, or focuses consciousness on other things. It is known that it has the effect of alleviating or curing pain, stiff shoulders, and other discomforts. On the other hand, it is known that when electrical stimulation (transcutaneous stimulation (also referred to as skin stimulation)) is applied to a living body through the skin, pain, stiff shoulders, and other discomforts can be alleviated or cured.

It is also known that multiple stimulations are more refreshing than regular stimulations, and irregular stimulations are more refreshing and therapeutically effective than regular stimulations.

Based on these facts, research is being conducted on methods to reduce or treat pain sensation, stiffness, etc. using these stimuli.

Conventionally, as electrical stimulation signal generation techniques for applying this type of electrical stimulation to a living body, especially its sympathetic/parasympathetic nerves, there have been methods for generating electrical stimulation signals in which the pulse frequency does not vary over time, for example; Special Publication No. 56-5543 (Literature) and Actual Publication No. 1983
There is a device disclosed in Publication No. -22921 (document).

The technique disclosed in the literature analyzes the frequency of a music signal and adjusts the frequency of the electrical stimulation signal from 10 to 100 according to the so-called 1/f fluctuation law, which states that the power spectral density of the signal is inversely proportional to the frequency f.
It is a technique that generates electrical stimulation signals while varying frequencies within the Hz range in relatively long duration units, such as 0.5 to 4 seconds.

The technique disclosed in the literature involves recording in advance on a recording medium an irregular pulse pattern in which the pulse generation frequency and the generation duration of the same pulse frequency vary as electrical stimulation signals, and then reproducing from the recording medium. This is a technique that follows the 1/f fluctuation law.

(Problems to be Solved by the Invention) By the way, if you listen to your favorite music, your nerves will synchronize with the tempo, and your tissues and cells will also synchronize with the same tempo, so you can enhance the effects of pain relief and the like. Therefore, this effect can be achieved by using the volume level (sound pressure level) as sound information to provide skin stimulation to the living body in accordance with the tempo of the music.

However, the above-mentioned conventional technology uses 1/f of sound.
Since this technique provides skin stimulation based on frequency according to the fluctuation law, there is a problem in that it is difficult to match the stimulation to the tempo of music.
Furthermore, when using a combination of auditory stimulation from music and sounds and skin stimulation (electrical stimulation) that reflects these sound information, the living body is able to treat psychogenic pain far more effectively than when using either stimulation alone. It is known to be highly effective. Furthermore, the effects of the treatment, etc. will be even greater if the auditory stimulation and the electrical stimulation are made so that there is no substantial time delay and the living body feels that both stimulations are received in almost real time (real time).

However, according to the above-mentioned conventional techniques, it is not possible to apply both types of stimulation to a living body as real-time stimulation. This causes the music or sound to pause (such as rests or when the sound pressure (volume) is low).
Since electrical stimulation is given to the living body even when the body is in a state of stress, it cannot be matched with the living body's experiential psychological relaxation, and therefore, from the living body's perspective, such electrical stimulation is nothing more than a constant change in the stimulation pattern. There was a problem in that the patient did not feel any pain, and the relief of pain and other therapeutic effects could not be expected to be that great.

In view of the above-mentioned conventional problems, the first object of the present invention is to provide a method for generating a low-frequency electrical stimulation signal that applies electrical stimulation (skin stimulation) to a living body in accordance with the tempo of auditory stimulation. be.

A second object of the present invention is to provide a method for generating a low frequency electrical stimulation signal that provides auditory stimulation and skin stimulation to a living body substantially in real time.

(Means for Solving the Problem) In order to achieve this objective, according to the low frequency electrical stimulation signal generation method of the present invention, direct sound information from the sound source is not used as control information for the electrical stimulation signal. This method is configured to read out control information stored in a control unit in advance and apply alternating current and voltage stimulation to a living body. In this case, the sound information from the sound source is used only for auditory stimulation.

In carrying out this invention, it is preferable that the control information be one or more types of information selected from waveform, frequency, and intensity, and that these control information can be selected and varied to optimal values for the living body by external input. be.

Furthermore, in practicing the invention, it is preferred that the current and voltage stimulation signals be alternately switched at random.

Furthermore, the time interval of this alternating switching can be randomly set within the range of several seconds to several tens of seconds. In particular, it is preferable to set the switching time interval to about 2 seconds to 1 minute.

Further, preferably, the frequency of the electrical stimulation signal used here is a low frequency within the range of 0 to 60 Hz.

(Operation) As described above, according to the method of the present invention, current or voltage control is performed based on the waveform of sound information to perform irregular modulation of the electrical stimulation signal. Therefore, by storing the frequency, waveform, and intensity of sound information such as one's favorite music in advance, the living body can be electrically stimulated (transcutaneous stimulation) in accordance with the tempo of the music. Therefore, it is possible to apply transcutaneous stimulation at a timing that the living body perceives as substantially real time, so that pain relief and therapeutic effects can be further enhanced in music therapy compared to conventional methods.

Further, according to the method of the present invention, since the current and voltage control methods are alternately switched to provide alternate stimulation, it is possible to avoid the living body becoming insensitive to current stimulation, and therefore to eliminate discomfort. Relief of pain effects,
It is possible to reliably improve the therapeutic effect.

Furthermore, according to the method of the present invention, the frequency of the electrical stimulation signal is set to a low frequency, for example, a frequency within the low frequency range of 0 to 60 Hz, so ``Hair raising'' and ``trembling'' are around 15Hz), which can relax both body and mind.

(Embodiments) Hereinafter, embodiments of the present invention will be described with reference to the drawings.

FIG. 1 is a block diagram showing a basic configuration for explaining this invention, and FIG. 2 is a block diagram showing a specific example of the configuration of a low frequency electrical stimulation signal generating device for explaining this invention. be.

In FIG. 1, the low frequency electrical stimulation signal generation device basically includes a stimulation signal generation section 10 for generating a low frequency electrical stimulation signal, and this stimulation signal generation section 1.
The device includes a host section 12 for selectively supplying data necessary for operating the 0, and an electrode section 14 for applying generated stimulation signals to the living body.

Description of Basic Configuration In this embodiment, the host unit 12 includes necessary conditions for the stimulation signal generation unit 10, such as amplitude (intensity), waveform, frequency, stimulation pattern, control method such as current control or voltage control, electrode It mainly includes an input section 20 for inputting various signals for initial setting of selection and other conditions, adjustment of appropriate conditions, start of stimulation signal generation, etc. Furthermore, this host unit 12 includes a suitable sound source device for generating music, etc., a speaker for reproducing sound information from the sound source device, an electroacoustic transducer such as earphones, or a device for visually displaying the generated electrical stimulation signal. It is also possible to provide a display section 21, etc., or to prepare these sound source devices as an external device (shown as a sound source device 16) without providing them in the host section 12, so that the stimulation signal generating section 1
It may be configured so that it can be connected to 0.

In this embodiment, the stimulation signal generator 10
The current and/or voltage method detects the volume level from the sound source device 16 and controls the physical quantity of the current and/or voltage stimulation signal, such as the frequency, amplitude (intensity), or number of pulses, in accordance with the detected volume level. Using a control method, while constantly modulating the electrical stimulation signal,
The configuration is such that the electrical stimulation signal is output. In this case, the frequency of the electrical stimulation signal can be selectively set to a certain low frequency within the preset frequency range of approximately 0 to 50 Hz that is comfortable for the person using the device. It is preferable to configure the following. Therefore, the stimulation signal generating section 10 mainly includes a control section including a CPU (central processing unit) for converting the volume level into a required control amount for controlling physical quantities and controlling other necessary controls. 30, a current control section 40 that controls the current according to this control amount, a voltage control section 50 that controls the voltage according to this control amount, and a voltage stimulation signal and a voltage stimulation signal generated from the current control section 40 and the voltage control section 50. It includes a control method selection section 60 for selecting a current stimulation signal and an output section 70.

Furthermore, in this embodiment, the stimulation signal generating section 10 generates a current and a voltage with a sound waveform of approximately 200 Hz or less when there is sound and a pseudo-generated sound waveform when there is no sound, regardless of the volume level. A waveform control unit 80 is provided for performing rhythm stimulation (also referred to as rhythm modulation) by controlling the rhythm of the electrical stimulation signal by performing waveform control.

Furthermore, in this embodiment, since the control unit 30 randomly switches between the current control method and the voltage control method regardless of music or sound information, the waveform and pulse that are the parameters of stimulation to the living body are controlled. Means are provided for generating width, frequency, intensity (amplitude), switching, etc. control signals. With this control means, as will be described later, the analog or digital pattern of the electrical stimulation signal of current or voltage can be set to any suitable stimulation pattern for each living body.

Description of Specific Configuration The specific configuration and control method shown in FIG. 2 will be explained below. In the figure, the same components as those shown in FIG. 1 will be described with the same reference numerals. Further, since the specific configuration and control method described in this embodiment are merely preferred examples, the present invention is not limited only to this embodiment.

<Description of Block Circuit> In FIG.
0 to a volume to DC level converter 91, and the resulting volume level signal is sent to an A/D converter 92.

On the other hand, the output from the amplifier 90 is
The sound is transmitted to an electroacoustic transducer 95 such as a speaker or earphone via an electronic volume 93 and an amplifier 94 whose volume can be adjusted using a SW, and is reproduced to provide auditory stimulation. Note that these reproduction systems do not necessarily need to be provided in this electrical stimulation device, and those provided in the external sound source device 16 may be used.

Further, if necessary, the output of the amplifier 94 can be configured to pass through the DC converter 22 of the display section 21 and display changes in the sound information on the light emitting display section 23 such as an LED, for example. Further, this light emitting display section 23 may be provided in the host section 12.

In this embodiment, the control unit 30 controls the host unit 12
A serial interface 31 that receives signals from the input section 20 wirelessly or by wire, and a CPU that performs various processes in accordance with the signals from this interface 31.
32. RAM where data necessary for processing by this CPU 32 is written and read as required
(Random Access Memory) 33, ROM (Read Only Memory) 3 that stores data necessary for processing etc. in the CPU 32 in advance and reads it when necessary.
4. Automatically outputs an arbitrary frequency as an internal clock for the data set by the CPU 32
A PTM (programmable time unit) 35, an output port 36 for outputting outputs including various control signals from the control unit 30 to other components, an input to the control unit 30, for example, a frequency 1 from the PTM 35.
It primarily comprises an input port 37 for receiving a signal for detecting the end of a cycle.

A portion of the output from the output port 36 is sent to the pulse number generator 96, the PTM 35 and the pulse number generator 96.
The signal is sent to the changeover switch 97 as a control signal.

In this embodiment, the current control section 40 and the voltage control section 50 each commonly include a waveform generation section 41 and a waveform selection section 42 composed of, for example, an electronic switch for selectively extracting the generated voltage waveform. The frequency clock section 4 of this waveform generating section 41
3, a frequency or pulse number control signal is sent through the changeover switch 97, and a frequency control signal is sent from the output port 36. Furthermore, data for changing the pulse width of the voltage waveform to be generated is sent from the output port to the pulse width data section 4 of this circuit 41.
Send to 4.

This waveform generating section 41 is provided with a waveform generating circuit 45 . This waveform generating circuit 45 is, for example, shown in FIG.
It is equipped with a large number of circuits that can individually output signals of various voltage waveforms as shown in . The configuration is such that each can be changed depending on data from the section 44. Such a waveform generation circuit 4
5. The frequency clock section 43 and the pulse width data section 44 can be easily formed using conventional electronic circuit technology, and there is no need for any special circuit configuration. A control signal from the output port 36 is used as a waveform select signal to determine whether at least one or two or more of these waveform generation circuits 45 are to be operated to output one or more required voltage waveform patterns. It is structured so that you can choose according to your preferences. Further, one or more types of voltage waveform patterns outputted from the waveform generation section 41 are selected by the waveform selection section 4.
2, it is configured so that it can be selected and taken out based on the waveform select signal from the output port 36 in the same way. The circuit configuration of this waveform selection section 42 can also be easily configured using conventional electronic circuit technology, and there is no need for this circuit to have any special circuit configuration.

One of the voltage waveform signals selected by the waveform selection section 42 is supplied to the current stimulation generation circuit 47 via the intensity (amplitude) setting circuit 46 of the current control section 40 . Further, the other voltage waveform signal is supplied to the voltage stimulus generation circuit 51 of the voltage control section 50.

In the current control section 40, an intensity setting circuit 46
The input voltage waveform signal is set to an arbitrary suitable amplitude by the control signal from the output port 36, and the input voltage waveform pattern is maintained in the current stimulation generating circuit 47. In other words, the voltage waveform pattern is the same as that of the voltage waveform. It converts the patterned current waveform into an electrical stimulation signal and outputs it.

On the other hand, in the voltage control section 50, the voltage waveform signal inputted to the supply voltage stimulation generation circuit 51 via the waveform selection section 42 is arbitrarily controlled as required by the intensity (amplitude) and frequency control signal from the output port 36. The signal is changed to an appropriate intensity and/or frequency and output as an electrical stimulation signal in the form of a voltage waveform.

Furthermore, in this embodiment, a control method selection section 60 is provided for selecting which method, current control or voltage control, should be used to apply the electrical stimulation signal to the living body as skin stimulation. This selection can be made by a selection method control signal from the output port 36, and depending on the need, only one of the current control method or the voltage control method is selected, or both control methods are selected. It is configured so that it can be selected alternately at random.

The electrical stimulation signal obtained through the control method selection section 60 is sent to the output section 70 of the low frequency electrical stimulation signal generator. This output unit 70 is connected to electrodes for applying skin stimulation to one or more required locations on the living body, and which electrode is selected can be controlled by an electrode selection control signal from the output port 36. Configure.

Furthermore, in this embodiment, the waveform control section 8
0, for example, a comparator 81 that detects the sound information from the amplifier 90, a low-pass filter 82 that passes sound information of approximately 200 Hz or less, and a rhythm generator 83 that generates a pseudo sound wave during the pause period of the sound information.
When the comparator 81 detects sound information, it selects the sound information of approximately 200Hz or less from the low-pass filter 82, and when it does not detect sound information, the rhythm generator 8 selects the sound information from the low-pass filter 82.
A selection switch 84 is provided for selecting pseudo sound information No. 3 and sending it to the waveform selection section 42 as a rhythm modulation (stimulation) waveform. On the other hand, this sound information is sent as a rhythm stimulation display signal to the control section via the A/D converter 92, and the rhythm display section 21 is configured to display the rhythm based on the control signal from the output port.

Control Method for Generating Electrical Stimulation Signal In the present invention, the frequency of the electrical stimulation signal for stimulating the skin is set to a low frequency. In this case, the frequency range is approximately 0 to 60 Hz, which the living body feels comfortable with. In this method, the electrical stimulation signal is modulated by one or both of current control and voltage control corresponding to the volume level from the sound source.

In the case of this electrical control method, the cells of the living body sense electric charges as energy, and in the case of the voltage control method, voltage is oscillated, so less current is needed to provide the same physical sensation that is good for the nerves. It is known that either control method provides a unique sense of pleasure to the living body.

In a practical example of the present invention, when modulating an electrical stimulation signal by controlling the frequency, amplitude, and number of pulses of current and voltage in relation to the volume level, a sound waveform of approximately 200 Hz or less is modulated without using the volume level. When performing rhythm modulation of the electrical stimulation signal by controlling the current and voltage using the waveform and pseudo-sound waveform at appropriate times, various control information (waveform, frequency , amplitude) to control the current and voltage patterns to modulate the stimulation pattern of the electrical stimulation signal.

In the following description, further reference will be made to FIGS. 4 to 16. Figure 4 is a diagram explaining table conversion, Figure 5 is a functional block diagram of the CPU 32, and Figure 6 is a diagram explaining table conversion.
1 to 14 are flowcharts of the operation, and each processing step is indicated by S.

[] Using volume level <Frequency modulation> First, turn on the power switch and operate the sound source device 16 to generate sound information such as music to provide auditory stimulation.

The sound information from the sound source device 16 is converted into a volume level of 8-bit data by a volume to DC level converter 91 and an A/D converter 92 in real time, as shown in the upper column of FIG. 4, for example.

On the other hand, the input section 20 of the host section 12 (for example,
(input key) to input necessary initial information such as modulation, waveform, frequency, electrode selection, control method, and other necessary initial information as treatment data to the control section 30 of the stimulation signal generation section 10. Based on this initial information
Processing is performed by the setting means 102 of the CPU 32 (S1), and the corresponding control information is read out from the ROM 34 or converted into required control information, and each of these control information is sent to the output port 36.
to each corresponding component (S2) to set initial conditions.

For example, a waveform select signal is sent to the waveform generation section 41 to activate the waveform generation circuit 45, and a control signal is sent to the pulse width data section 44 to initialize an appropriate pulse width.

In addition, the initial frequency information is sent to the frequency clock section 43, and the frequency at which the living body feels the maximum stimulation when the waveforms of the electrical stimulation signals are the same is set, for example.
The frequency of the voltage waveform signal from the waveform generation circuit 45 is initially set to 30Hz. The initial setting of this frequency is set regardless of the presence or absence of sound information from the sound source device 16.

At the same time, a control signal is sent to the voltage control and current control method selection section 60 to select an electrical stimulation signal based on one of the control methods.

Furthermore, the intensities of these electrical stimulation signals are set each time by sending a control signal read from the ROM 34 to the intensity setting circuit 46 and the voltage stimulation generation circuit 51 in accordance with the selection at the input section 20. This intensity can be adjusted and set until the user feels comfortable.

When this stimulation intensity is appropriate, host part 1
2, the start key of the input unit 20 is turned on, a start input is sent to the control unit 30, treatment start data is sent to the stimulation signal generation unit 10 through the processing of the CPU 32 (S3), and the control unit 30 converts the A/D converter. The acquisition of the volume level starts from 92 (S4). This acquisition is performed by sampling by the CPU 32, and each volume level obtained for each sampling is once written to the RAM 33 (S5).
The data is sequentially read from the RAM 32 to the CPU 32 as required (S6), and the CPU 32 converts the volume level of the 8-bit data into 16 levels (S7). During this level conversion, not only when the volume is "0", but also when the volume is low, the electrical stimulation signal intensity is forced to the "0" level. Each of these 16 volume levels is converted to a corresponding frequency in the low frequency range (S8). This conversion is performed by, for example, storing conversion frequencies corresponding to each volume level in advance in the ROM 34 in the form of a table, comparing the frequency conversion table with the frequency conversion table for each volume level, and reading out the corresponding frequency (S8). This frequency information is sent to the corresponding component via the output port 36 (S9). In this case, sampling is preferably performed at a rate that the organism perceives as substantially real time, e.g.
It is preferable to carry out the periodicity within the range of 0.01 to 0.5 seconds. Also, the frequency conversion table is, for example, the fourth one.
As shown in the figure, for each of the 16 volume levels, the stimulation frequency ranges from 0 to 60 Hz, preferably 0 to 30, which is the stimulation frequency that the living body feels most comfortable.
Assign individual frequencies within the Hz range. For example, as can be understood from Figure 4, the volume level "0" is 1.5Hz, "1" is 2Hz, ... "5" is 5Hz, ... "10" is 10Hz, "11" is 15Hz, ... …
"15" is set as 30Hz. In this way, the CPU 32 includes a conversion means 102 that performs such sampling and converts the frequency.
(Figure 5).

When the volume level is frequency-converted for each sample and outputted sequentially from the output port 36, this frequency is converted to the frequency of the frequency clock section 43 of the waveform generation section 41.
and is supplied to the voltage stimulation generation circuit 51, and the initially set frequency is updated to a new frequency that immediately corresponds to the volume level that is sequentially sent.Therefore, analog control of the frequency of the current or voltage is performed. , frequency modulation of the electrical stimulation signal is achieved automatically in an analog manner.

In this way, music/sound is used as an auditory stimulus, and the volume level from the sound source device 16 is sampled in substantially real time with the auditory stimulus, and electricity is always generated at a frequency corresponding to the volume level at the same time as this sampling time. Transcutaneous stimulation is provided by modulating the frequency of the stimulation signal.

The greatest feature of this frequency modulation is the near real-time sampling and the setting of electrical stimulation (corresponding to transcutaneous stimulation) that responds immediately to this sampling. In this embodiment, when the volume (sound pressure) level is "0" or an extremely low level (one-sixteenth of the maximum level or less), the frequency is set to, for example, 1.5 Hz or less. In this way, when the music is paused or the volume is low, the waiting time until the next stimulus is, for example, 1 second at 1 Hz, 2 seconds at 0.5 Hz,
At 0.25Hz, it is 4 seconds. Therefore, in terms of actual music, transcutaneous stimulation is not performed when the music is at rest or when the volume is low. Since this no-stimulation time of transcutaneous stimulation is substantially synchronized with the no-stimulation time of auditory stimulation, the cerebral cortex is innervated by the world of music based on experiential ideas due to the music you like, and pain can be felt. It makes you feel less and the therapeutic effect increases.

By the way, if the waiting time until the next transcutaneous stimulation becomes long, there may actually be cases where the patient does not immediately respond to the auditory stimulation. Therefore, in this embodiment, the control section 30 of the stimulation signal generation section 10 constantly observes this waiting time in terms of the conversion frequency and the volume level, and if the waiting time becomes longer, the control section 30 of the stimulation signal generating section 10 changes the newly sampled volume level. The frequency compulsory conversion means 103 is provided to forcibly convert the frequency to a frequency corresponding to the frequency.

An example of the flow of operation of this frequency forced conversion means 103 will be explained using FIG. 8.

First, a determination process is performed as to whether the sampled volume level is 1/16 or less of the maximum level (S10). If yes (Y), the treatment intensity level of the volume level is set to the "0" level (S10). If no (N), a determination process is performed as to whether the current frequency is, for example, 5 Hz or less (S12). When the volume level is below 1/10,
The treatment intensity is set to 0 (S11). Next, if the frequency is higher than 5Hz, 1 of this frequency
A process for determining whether the cycle has ended is performed (S13). If one cycle has not been completed, the treatment intensity is set to the set intensity (initial setting intensity) (S16). If one cycle has been completed, the volume level is converted to a frequency corresponding to the volume level obtained in the next sampling (S15), and outputted through step S16.

If the current frequency is 5 Hz or less in the judgment process in step S13 above, it is compared with the volume level at the previous sampling (S14), and if the current volume level is higher, the step
In the process of S15, the frequency is set to a frequency that corresponds in intensity to the current volume level, and then the process of S16 is performed and output. Furthermore, if the current volume level is low, the process of step S16 is performed. This series of processing is always performed while the electrical stimulation signal generator is in operation. In the above-mentioned embodiment, a case was explained in which the conversion means 102 and the forced frequency conversion means 103 were provided as separate functional blocks, but it is also possible to adopt a configuration in which the conversion means 102 includes the forced conversion means 103. . Further, the operation flow is not limited to the above-described flow, and a different flow may be used.

<Amplitude Modulation> First, similar to the case of frequency modulation, initial settings are performed (FIGS. 5 and 6). In this case, the initially set intensity is the maximum intensity that provides maximum stimulation to the living body, and this is the set intensity. This setting strength is written in the RAM 33 and read out at any time.

Next, when the volume level of the 8-bit data is sequentially captured by sampling, the set intensity is sequentially adjusted to the intensity (amplitude) corresponding to this newly captured volume level within the range of 0 to 100%. is updated in real time, thus achieving amplitude modulation of the electrical stimulation signal and thus modulation of the transcutaneous stimulation intensity. This amplitude (intensity) conversion is constantly performed.

In this embodiment, this amplitude modulation is
This can be mainly performed using the treatment intensity setting means 104 of No. 2.

This amplitude modulation process (see Figure 9) first involves
The set intensity is read from the RAM 33 (S20), and then the volume level of 8-bit data is read from the RAM 33 (S21). Then, the following formula ()
In order to calculate the equation, this 8-bit data of the sound quality level is divided by 256, and the resulting quotient is multiplied by the set intensity to calculate the treatment intensity, that is, the amplitude control value (S22). Note that this calculation process is not limited to this.

Treatment intensity = Setting intensity x {(8-bit data of volume level) / 256} ... () In this case, preferably, the amplitude control value is 24 levels of electrical stimulation signal intensity within the range of 0 to 100% of the setting intensity. It is best to set it so that you get Further, when the volume level of music/sound is "0" or extremely low, the electrical stimulation signal intensity is forcibly set to "0". However, even if this intensity is not set to "0", the intensity will also decrease when the volume level is low, so it will not be felt as a living body, and the bodily sensation will match the music/sound.

Furthermore, although an example has been described in which arithmetic processing is performed by the functional block of the treatment intensity setting means 104, the ROM 34
The treatment intensity (amplitude control value) may be stored as a conversion table in , and this conversion table may be read out and converted to the treatment intensity.

The amplitude control value thus obtained is outputted from the output port 36 and sent to the intensity setting circuit 46 and the voltage stimulation generation circuit 51 to modulate the amplitude of the current and voltage stimulation signals. In this case, as in the case of frequency modulation, either the current or voltage control method is selected by the control method selection section 60.

In the case of this amplitude modulation, as in the case of frequency modulation, the volume level from the sound source device is sampled in substantially real time with the auditory stimulation, and the amplitude is converted at the same time as the sampling time to convert the amplitude of the electrical stimulation signal. It is set in real time within the range of 0 to 100% of the set intensity.

The feature of this amplitude modulation is that no output stimulation is performed when the music is paused or the volume is low.As with frequency modulation, the non-stimulation time of transcutaneous stimulation is
It can be created in conjunction with music, and is highly effective in music therapy.

<Pulse number modulation> In this case as well, initial settings are performed in the same way as in the case of frequency modulation described above, but instead of the frequency, the pulse number generator 96 generates, for example, 16 pulses/second (corresponding to 30Hz). Initial settings are made to generate pulses at a pulse rate (FIGS. 5 and 6).

Next, when the volume level of the 8-bit data is sequentially captured by sampling, the number of pulses corresponding to this newly captured volume level is sequentially set within the range from the initial setting pulse number to the maximum pulse number. is updated in real time, thus achieving control of the electrical stimulation signal and thus achieving pulse number control of transcutaneous stimulation. This pulse number modulation is always performed.

This pulse number modulation, in this example,
This can be mainly performed using the pulse number setting means 105 of 32.

In the pulse number modulation process (see Figure 10), first,
The volume level divided into 16 levels is read from the RAM 33 (S23), then the corresponding pulse number conversion value is obtained by table conversion in the ROM 34 (S24), and then the calculation according to the following formula () is performed ( S25).

Pulse number control value = (16-step conversion value - 1)
...() According to this embodiment, a pulse number control value is calculated according to equation () and sent from the output port 36 to the pulse number generator 96, thereby immediately responding to the sampled volume level. to generate a pulse at the corresponding pulse rate, and switch 97
The signal is then sent to the frequency clock section 43 of the waveform generating section 41. Therefore, the pulse rate at which the current and voltage stimulation signals are generated as pulses can be controlled. In this case, the number of pulses is preferably within the range of 0 to 30 pulses/second that the living body feels comfortable with.

According to this formula, the number of pulses becomes "0" when the music is at rest or when the volume is low.

Note that the calculation of the pulse number control value is not limited to equation (), and other calculation methods may be used. Further, instead of these calculations, the pulse number control values corresponding to the volume levels may be stored in a table in the ROM 34, and the values may be obtained by converting the table.

Even when pulse number modulation is performed in this manner, percutaneous stimulation can be applied substantially in real time with auditory stimulation, as in the case of frequency modulation described above.

[] Not using volume level <Rhythm modulation> This process will be explained (Fig. 11). In this case, setting conditions such as modulation, waveform, stimulation pattern, control method, electrode selection, etc. are input as treatment data from the input unit 20 of the host unit 12 to the control unit 30. This process will be explained. As in the case of frequency modulation and the like described above, initial settings are performed based on these setting conditions. During this initial setting, a waveform with a large wave height is used to make it easier to feel the intensity. Then, for example, the treatment is started when a stimulation pattern that the living body feels is optimal stimulation is reached. First, the modulation method setting means 106 of the CPU 32 sends rhythm modulation command information from the output port to the waveform control section 80, and the waveform control section 80 is activated (S30). Sound source device 1
6 (S31), and if it is outputting, the comparator 81 detects this by, for example, level comparison, and switches the selection switch 84 to the low-pass filter 82 to detect sound information below approximately 200Hz. The sound information is sent to the waveform selection section 42 as a rhythm modulation waveform (S32). on the other hand,
If there is no sound information, this comparator 81
As a result, the pseudo sound waveform from the rhythm generator 83 is sent to the waveform selection section 42 as a rhythm modulation waveform (S33). Next, in response to a command from the modulation method setting means 106, the waveform selection section 42 is switched to select only the rhythm modulation waveform and set to send it to the subsequent stage (S34).

From this waveform selection section 42, the voltage stimulation generation circuit 5
1 and also sends it to the current stimulation generation circuit 47 via the intensity setting circuit 46 (S32). The rhythm and/or intensity of the current and stimulation stimulation signals are respectively controlled using both rhythm modulation waveforms (S33) and output as electrical stimulation signals using either current or voltage control as in the case of the other modulation methods described above. let Therefore, rhythmic and intense stimulation can be given to the living body.

In this embodiment, the low-pass filter 82 with a frequency of approximately 200 Hz or less is used because the stimulation obtained by a stimulation pattern with a frequency in that range is a stimulation that matches the bass and drums.

This rhythmic stimulation can also alleviate or treat the discomfort of the living body.

[] Stimulation pattern modulation without using a sound source device <Alternate switching of current and voltage control methods> In this case, the control unit 30 is configured to automatically change the selected parameters of the stimulation pattern regardless of the music. It is. Typical stimulation parameters include waveform, pulse width, frequency, and intensity.

In this embodiment, stimulation pattern modulation processing will be explained using two examples in which frequency and intensity are variable parameters (FIGS. 2, 5, and 12).

First, the initial setting values of each parameter and the variable parameter values of frequency and intensity are stored in the ROM 34 in advance.

This stimulation pattern modulation process will be explained.

Variable Frequency As in the case of each modulation method described above, the modulation method setting means 106 commands stimulation parameter modulation based on a command from the input section 20 (S40), and the setting means 101 sets the waveform, pulse width, and Make initial settings for intensity (S41). Next, based on this command, the stimulation parameter setting means 107 is operated to read the frequency from the ROM 34 and output it from the output port 36 to the waveform generation section 41 and the voltage stimulation generation circuit 51 (S42). This frequency may be fixed or may vary randomly. Next, the electrical stimulation signal is controlled in the same manner as in the case of frequency modulation described above (S43). Next, based on the above-mentioned modulation method setting means 106 selecting this modulation method, this means 106 selects the control method selection unit 60.
A command is given to alternately output current and voltage stimulation signals at a constant or random switching speed, and these stimulation signals are outputted alternately (S44). Therefore, stimulation can be applied alternately to the living body.

This alternating switching is performed by reading data from the ROM 34 and outputting it in accordance with commands from the input section 20. This process can also be performed by the setting means 101.

Variable intensity In this case, processing is basically the same as in the variable frequency case described above, so
Processing may be performed in which frequency in FIG. 12 is replaced with intensity (amplitude). However, to initialize the frequency, the setting means 101 sends a control signal to the PTM 35, and the PTM 35 automatically locks the frequency. By varying the intensity, the stimulation pattern can be modulated and alternating stimulation can be applied to the living body.

Thus, in any type of stimulation pattern modulation, the stimulation pattern is controlled by a program stored in the CPU 32 in advance.

By the way, in the case of this stimulation pattern modulation, the current and voltage stimulation signals are alternately switched, and the switching time is several seconds to several minutes, but preferably about 2 seconds to 1 minute. .

The reason why such alternating stimulation is provided by alternating switching is as follows. For example, if biological stimulation is performed using current control with a sine wave or exponential waveform and voltage control with a square wave or needle waveform, no stimulation will occur under current control even if the current value is the same as during voltage control. Even if the living body feels unstimulated, electric current control imparts an electric charge to the living body, so current stimulation is effective during anesthesia, children, or people who dislike electricity. However, since current stimulation alone does not produce any sensation, a sensitive stimulation is provided by alternately switching between voltage and current stimulation.

Flow of main control operations of this device FIG. 13 is a diagram showing an example of the flow of main operations of this device.

First, it is determined whether a signal is being received from the input section 20 (S50), and if it is being received, the data for that determination and each data are set, or if it is not being received, it is directly transmitted to the next step. Proceed to frequency modulation processing.

Next, it is determined whether or not frequency modulation is to be performed (S52). If there is such a command, frequency modulation processing is performed (S53), or if there is no such command, the process directly proceeds to the next process.

Next, it is determined whether it is amplitude modulation or not (S54).
If there is such a command, amplitude modulation processing is performed (S55), or if there is no such command, the process directly proceeds to the next process.

Next, it is determined whether or not there is rhythm modulation (S56). If there is a command, rhythm modulation processing is performed (S57), or if there is no command, the process directly proceeds to the next process.

Next, it is determined whether or not pulse number modulation is required (S58), and if there is a command, the frequency modulation process is performed (S59), or if there is no command, the process goes directly to the next process. move on.

Next, it is determined whether there is no modulation (S60),
If there is no modulation command, a process without modulation is performed (S61), or if there is a modulation command, the process directly proceeds to the next process.

Next, other necessary processing, including stimulation pattern processing, etc., is controlled.

Note that this process is repeated during the operation of this device. The process of determining the type and presence of each modulation method is performed by the modulation method setting means 106 of the CPU 32, and the results are sent to the frequency forced conversion means 103, the treatment intensity setting means 104, and the treatment intensity setting means 104, respectively.
A signal is sent to the pulse number setting means 105 and stimulation parameter setting means 107 to start their respective processes.

Processing of volume level data by the CPU In Fig. 5, from the A/D converter 92
The volume level data input to the CPU 32 is first converted into 8-bit data from the A/D converter 92 by the conversion means 102 as shown in the flowchart of FIG. 14, and then set in the RAM 33. (S63). The set data is converted into 16 levels and set in another area of the RAM 33 (S64).

Current stimulation generation circuit and voltage stimulation generation circuit Next, the current stimulation generation circuit 4 explained in FIG.
7 and the voltage stimulation generating circuit 51 will be briefly explained with reference to FIGS. 15 and 16.

Both of these circuits 47 and 51 can be easily assembled in a hardware configuration using conventionally known electronic circuit technology.

Current Stimulation Generating Circuit FIG. 15 shows a block diagram of an example of this circuit. As already explained, this circuit is a circuit that outputs a current having the same waveform as the input voltage waveform.

This circuit mainly uses, for example, an operational amplifier, a photocoupler, a Darlington circuit, etc., and is composed of a first stage 110, a second stage 120, and a third stage 130.

The first stage 110 uses an operational amplifier 111 to convert the voltage waveform into a current waveform at a constant voltage level.
and a photocoupler light emitting element 112 to convert input voltage into optical output.

The second stage 120 is a photocoupler light receiving element 1
21, a current-to-voltage conversion circuit 122 that converts the current from the light receiving element into voltage, and an operational amplifier 123 that amplifies the voltage, and outputs the voltage.

The third stage 130 further converts the voltage to the operational amplifier 1
After being amplified at 31, it is converted into a current to be sent to the Darlington circuit, thereby generating an output current. At this time, by feeding back the output of the Darlington circuit 132 to the operational amplifier 131 side, it is possible to output a current with a waveform that always matches the input voltage waveform even if the impedance of the biological body to which this output current is applied changes. It has been done.

The circuit configuration of this current stimulation generating circuit 46 is not limited to the configuration of this embodiment, and may have other configurations.

Electrical Stimulation Generating Circuit This circuit is a circuit that simply amplifies the input voltage, and an example of its configuration is shown in a block diagram in FIG. 16, for example. This circuit 51 is composed of an operational amplifier 141 and a push-pull amplifier 142 for amplifying its amplified voltage output, and outputs a voltage whose amplitude and/or frequency of the input voltage has been changed as required.

This circuit 51 is also not limited to the circuit configuration of the embodiment described above, and may have another configuration.

The configuration of the control and/or device for achieving the present invention is not limited to the method and configuration described in the above-described embodiments, and it is clear that various changes can be made within the scope of the present invention.

For example, the configuration of the device shown in FIG. 2 and the like may be other configurations, and its operating method is not limited to the operating procedure described above.

It is also possible to generate an electrical stimulation signal by arbitrarily combining the frequency modulation, amplitude modulation, pulse modulation, rhythm modulation, and stimulation pattern modulation (alternate stimulation) described above.

(Effects of the Invention) As is clear from the above description, according to the present invention, control information stored in the control unit is read out in advance, and the living body is electrically controlled in real time in accordance with the tempo of one's favorite music. Because it can stimulate
In music therapy, pain relief and therapeutic effects can be further enhanced than when following the conventional 1/f fluctuation law. Therefore, there is no need to use a sound source during treatment. Furthermore, when a sound source is used during treatment, it is sufficient to simply use sound information from the sound source as auditory stimulation during treatment, or when the sound source is in a silent state, the method of the present invention can be used for treatment even during the silent period. It can be performed.

Further, according to the present invention, since alternating stimulation is applied by alternating current and voltage control methods, it is possible to avoid the living body becoming insensitive to electrical stimulation, thereby eliminating discomfort and pain effects. It is possible to reliably alleviate the symptoms and improve the therapeutic effect.

Furthermore, since it uses low-frequency electrical stimulation signals, it is possible to achieve mental and physical relaxation.

[Brief explanation of drawings]

FIG. 1 is a block diagram showing the basic configuration of a low frequency electrical stimulation generator used to explain the present invention, and FIG. 2 is a block diagram showing a specific example of the configuration of the low frequency electrical stimulation generator used to explain the invention. FIG. 3 is a voltage waveform diagram for explaining this invention, FIG. 4 is a diagram showing a frequency conversion table for explaining this invention,
FIG. 5 mainly serves to explain this invention.
Block diagram for explaining the functions of the CPU, Part 6
14 are flowcharts of operations to explain the present invention, FIG. 15 is a block diagram showing an example of the configuration of a current stimulation generation circuit to explain the present invention, and FIG.
The figure is a block diagram showing an example of the configuration of a voltage stimulation generating circuit for explaining the present invention. 10... Stimulus signal generation section, 12... Host section,
20... Input section, 30... Control section, 40... Current control section, 50... Voltage control section, 60... Control method selection section, 70... Output section, 80... Waveform control section.

Claims (1)

[Claims] 1. When generating an electrical stimulation signal for applying electrical stimulation to a living body, control information stored in a control unit in advance is read out to control current and voltage stimulation signals, and these current and voltage stimulation signals are A low frequency electrical stimulation signal generation method characterized by outputting stimulation signals alternately as electrical stimulation signals. 2. Claims characterized in that the control information for the current and electrical stimulation signal is one or more types of information selected from waveform, frequency, and intensity, and the control information is selectable and variable by external input. The method for generating a low frequency electrical stimulation signal according to item 1. 3. The low frequency electrical stimulation signal generation method according to claim 1, wherein the current and voltage stimulation signals are alternately switched at random. 4. The low frequency electrical stimulation signal generation method according to claim 3, wherein the time interval of the alternating switching can be randomly set within a range of several seconds to several tens of seconds. 5. The method for generating a low frequency electrical stimulation signal according to claim 1, wherein the frequency of the electrical stimulation signal is a low frequency within a range of 0 to 60 Hz.