JPH0332341Y2 - - Google Patents

Description

[Detailed Description of the Invention] [Industrial Application Field] The present invention relates to an apparatus for continuously collecting body fluids from laboratory animals such as mice, rats, and hamsters.

[Conventional technology]

Conventionally, for example, in order to collect body fluids (gastric juice, bile, lymph fluid, urine, etc.) from a laboratory animal after surgery at regular intervals, one end of the body fluid collection pipe was connected to the animal after surgery, and the animal was restrained in a retainer. A body fluid collection container such as a test tube is connected to the other end of the body fluid collection pipe, and the body fluid collection container is replaced every hour, for example, to collect body fluid whose properties change over time.

[Problem to be solved]

The conventional technology described above requires a great deal of labor because it collects body fluids at regular intervals over a long period of time, including during the night, and especially when there are multiple animals whose body fluids are collected, it is physically and mentally stressful. In addition, not only is it necessary to manually store the body fluid collection container in a refrigerator, but also the body fluid collection is performed in a laboratory atmosphere. There were a number of problems, including the possibility that body fluids would decompose due to outside temperature.

[Means to solve problems]

The structure of the present invention, which solves the problems of the prior art, is that a retainer is provided on the upper part of the frame to restrain the animal after surgery, and a retainer is provided in the frame below the retainer to restrain the animal. A large number of body fluids such as test tubes are collected at each set time by holding the lower end of the body fluid collection pipe with one end attached to the frame body, and moving intermittently at set time intervals. The present invention is characterized in that a container holder having containers is provided, and each of the body fluid collection containers is placed in a cooling atmosphere provided in the frame.

〔Example〕

The embodiments of the present invention will be described in detail with reference to the drawings.

FIG. 1 is a front view schematically showing the entire apparatus, FIG. 2 is a plan view of the same container holder, and FIG. 3 is a plan view showing another embodiment of the container holder.

1 is a frame body, and a shelf board 2 is provided on the upper part of this frame body 1, and on this shelf board 2, a known retainer for restraining laboratory animals 3 such as mice, rats, hamsters, etc. is installed. 4 is placed. , in Figure 1, 1
Although only one retainer 4 is installed, a plurality of retainers are installed. The animal 3 has undergone surgery, and one end of the body fluid collection pipe 5 is connected to the surgical site, and the other end of the body fluid collection pipe 5, that is,
The lower end is fixed in position below the shelf board 2 by a holder (not shown) 2.

Reference numeral 6 denotes a water tank formed in the frame 1 on the lower side of the shelf board 2. In this water tank 6, a disc-shaped container holder 8 of a body fluid collection container 7 is placed intermittently above the water surface in the water tank 6. It is rotatably provided. As shown in FIG. 2, this disk-shaped container holder 8 has a large number of holes 9 (12 holes in this embodiment) formed at equal intervals around the periphery, and each hole 9 is filled with the body fluid such as a test tube. The collection containers 7 are inserted and supported, and each body fluid collection container 7 of the container holder 8, which rotates intermittently every set time (for example, one hour), faces directly below the lower end of the body fluid collection pipe 5 at each set time. , the lower end attachment position of the body fluid collection pipe 5 and the position of the body fluid collection container 9 of the container holder 8 are determined.

The container holder 8 is fixed to the tip of a rotating shaft 11 that extends vertically through the bottom plate of the water tank 6 with a seal structure 10, and this rotating shaft 11 is intermittently rotated with respect to the frame 1. A worm gear 12 is attached to the lower end of the rotating shaft 11.
Attach the motor 13 to this worm gear 12.
A worm 14 driven by a worm 14 is engaged with the worm 14. Further, the circuit of the motor 13 is configured to rotate by a set number of rotations at each set time by a timer device 15, and the container holder 8 is configured to rotate, for example, 1/12 per hour. It is.

Further, a cooler 16 is connected to the water tank 6 to circulate and cool the water in the water tank 6, and the water in the water tank 6 is controlled at, for example, about 5°C. The water level in each body fluid collection container 7
It is desirable to have higher than expected levels of body fluids collected within the body.

In the above embodiment, as shown in FIG. 2, the container holder 8 was formed into a disk shape, and was intermittently rotated by a set angle by a rotating shaft 11 at set times, but as shown in FIG. The container holder 8a may be made of a plate having a rectangular planar shape, and twelve holes 9a may be formed at regular intervals in the container holder 8a.
In the case of this container holder 8a, the container holder 8a is moved by a set stroke at each set time in the direction of the arrow, and each body fluid collection container 7 that can be supported thereon is sequentially moved at each set time at the dripping end of the body fluid collection pipe 5. Let them face the situation. For this reason, the container holder is not limited to the embodiments shown in FIGS. 1 and 2.

It should be noted that a plurality of the container holders 8, 8a and the intermittent rotation mechanism related thereto are provided in the frame 1, so that body fluids from a plurality of animals can be collected simultaneously and separately. Furthermore, it is configured so that different body fluids can be collected from multiple locations of the same animal at the same time.

In the figure, 17 is a positioning cam provided on the rotating shaft 11, and 18 is a micro switch that turns on or off the motor circuit using the cam 17. By the operation, the body fluid collection container 7 can be positioned with respect to the body fluid collection pipe 5.

[Effect of idea]

As described above, according to the configuration of the present invention, the following effects can be obtained.

(a) The collection of body fluids can be automated, resulting in significant labor savings.

(b) Since the body fluid collected in the body fluid collection container is always kept in a cooling atmosphere, decomposition of the body fluid due to the influence of outside temperature is reasonably prevented, and data on various body fluids can be refined.

[Brief explanation of drawings]

Figure 1 is a front view schematically showing the position of the present invention;
The figure is a plan view of the container holder, and FIG. 3 is a plan view of another embodiment of the container holder. 1...Frame body, 2...Shelf board, 3...Animal, 4...
Retainer, 5... Body fluid sampling pipe, 6... Water tank, 7
...body fluid collection container, 8,8a...container holder,
9, 9a...hole, 10...seal structure, 11...
Rotating shaft, 12...worm gear, 13...motor, 14...worm, 15...timer device,
16...Cooler.

Claims (1)

[Claims for Utility Model Registration] (a) A retainer is provided on the upper part of the frame to restrain the post-operative animal, and one end of the frame is attached to the animal below the retainer for body fluid collection. (b) The frame body has a number of body fluid collection containers such as test tubes that move intermittently at set time intervals and that face directly below the lower end of the body fluid collection pipe at each set time. A continuous body fluid collection device for animals, characterized in that a container holder is provided, and (c) each of the body fluid collection containers described above is placed in a cooling atmosphere provided in the frame.