JPH03277375A - Organism detention tool - Google Patents

Abstract

PURPOSE:To make the insertion of a detention tool into a biological part easy and to prevent a biological system impaired by performing moderate self- expansion by forming a detention tool main body by mixing a high water absorptive material, and comprising it by setting the contention ratio of the high water absorptive material dif-ferently partially. CONSTITUTION:The contention ratio of the high water absorptive material in both terminal parts 3, 3 of a tube main body 2 is increased higher than that of an intermediate part. Therefore, when water absorption to the tube main body 2 is performed, the main body is expanded as a whole, and inner and outer diameters are increased, however, since the contention ratio of the high water absorptive material at both terminal parts 3, 3 of the tube main body 2 is set higher than that of the intermediate part 4, larger expansion occurs, and it is expanded in horn shape, which enables the tube main body to be staged. The biological system can be prevented impaird since a processing tool main body is expanded extremely moderately and successively.

Description

[Detailed Description of the Invention] [Industrial Application Field] The present invention relates to an in-vivo indwelling device for securing the duct by indwelling it particularly in a biological duct, such as the esophagus, bile duct, blood vessel, or urethra. .

[Prior Art] In general, in-vivo indwelling devices that are inserted and placed in constricted sites of biological ducts such as the esophagus, bile ducts, blood vessels, and urethra to secure the ducts are:
JP-A-60-220030 and JP-A-62-201
This is proposed in Publication No. 163. JP-A-60-2
The one disclosed in No. 20030 has a prosthesis made of a shape memory alloy, and is disclosed in Japanese Patent Application Laid-Open No. 62-2011.
The device disclosed in Japanese Patent No. 63 is an indwelling device made of a shape memory polymer. These are small until they are inserted into the body, and after they are inserted and placed inside the body, they expand due to body heat. Since this conventional device is made of a shape memory alloy or a shape memory polymer alloy, it is thin and easy to insert into a living body for indwelling.

Once inserted into a living body, it expands or deforms into an effective shape due to its own shape memory effect.

[Problems to be Solved by the Invention] However, since the above-mentioned conventional devices are formed of shape memory alloys or shape memory polymers, they deform rapidly when they reach the deformation temperature due to body temperature after being inserted into a living body. and expand it. As a result, the lumen portion in which the indwelling device is installed is rapidly expanded, which may cause lacerations or perforations in the living body.

The present invention has been made with attention to the above-mentioned problems, and its purpose is to facilitate insertion into an in-vivo site, and
It is an object of the present invention to provide a highly safe in-vivo indwelling device that slowly self-expands and does not damage living tissues.

[Means for Solving the Problems] In order to solve the above-mentioned problems, the present invention provides an indwelling device that is introduced into an in-vivo site and indwelled at that site, by incorporating a highly water-absorbing material into the body of the indwelling device. The content of the superabsorbent material is partially varied.

[Function] When the indwelling device is placed at the target site within the living body, the highly water-absorbent material absorbs water and engraves. Also, expansion action, removal prevention action, and straying (movement of the indwelling device)
It reliably transforms into a form that has a preventive effect, etc. Moreover, since the treatment instrument main body made of a highly water-absorbent material is engraved very slowly and continuously, no damage is caused to living tissue.

[Embodiment] FIGS. 1 to 3 show a first embodiment of the present invention. The in-vivo indwelling device in this first embodiment is a drainage device (ERB) that is inserted into the bile duct endoscopically and indwelled.
D) This is an example of tube 1.

The tube body 2 of the drainage tube 1 is made of a biocompatible material and is formed into a cylindrical shape having an equal diameter over its entire length. This material includes, for example, a resin base material such as silicone elastomer, polyurethane elastomer, or ethylene vinyl alcohol (EVA), into which a superabsorbent resin as a superabsorbent material is mixed. Examples of superabsorbent resins include starch-polyacronitrile hydrolyzate, starch-polyacrylate, carboxymethylcellulose and its derivatives, vinyl acetate-
Examples include methyl acrylate copolymer, crosslinked polysodium acrylate, and the like, such as Sumikagel and Our Arich (trade name).

In the drainage tube 1, the mixing ratio of the super absorbent material to the resin of the base material is partially different. In this embodiment, the content of the super absorbent material in the end portions 3.3 of the tube body 2 is higher than that in the middle portion. Therefore, when water is absorbed into the tube body 2, the entire body is engraved and the inner and outer diameters are increased as shown in FIG. Since it is set higher than the middle part 4, it is engraved particularly large and spreads out like a trumpet.

FIG. 3 shows a state in which the drainage tube 1 is inserted and left in a constricted site 6 of the bile duct 5.

7 is the duodenum, 8 is the duodenal papilla, and 9 is the pancreatic duct.

Drainage tube 1 is introduced endoscopically and placed at its placement site. The tube body 2 absorbs the surrounding water such as bile and engraves it as a whole. It grows over several days. Then, a sufficient duct that communicates the bile duct 5 with the duodenum 7 is formed. Furthermore, since the content of the superabsorbent material in both end portions 3, 3 of the tube body 2 is set higher than in the middle portion 4, the engraving is particularly large, and the portion 3.3 is greatly expanded into a trumpet shape. .

The trumpet-shaped end portions 33 that are widened widely function as a stopper to prevent the drainage tube 1 from being pulled out.

In addition, since the tube body 2 is made of a highly water-absorbent material, its expansion progresses slowly and continuously to expand the stenosis site 6, which causes less stimulation to the living body and prevents damage. to ensure safety.

4 and 5 show a second embodiment of the present invention. This embodiment relates to the drainage tube 1 like the above embodiments, but the portion 3.3 in which the proportion of highly absorbent material is increased is located closer to the middle side than both ends of the tube body 2.

The rest is the same as that of the above embodiment.

In this way, parts 3 and 3 where the proportion of super absorbent material is increased
Since it is constructed so that it is moved toward the middle part, when it is water-absorbed engraved, it bulges out into a rounded mountain shape as shown in Figure 5. of course,
The entire piece is also engraved and the inner and outer diameters are enlarged.

6 and 7 show a third embodiment of the present invention. This embodiment relates to a drainage tube 1 like the above-mentioned embodiments, but the portion 3 in which the proportion of highly absorbent material is increased is only at one end of the tube body 2. This one end portion 3 is tapered before being inflated to facilitate insertion. The rest of the structure is similar to that of the above embodiment.

Since the portion 3 in which the proportion of superabsorbent material is increased is only at one end of the tube body 2, when it absorbs water and expands, the one end portion 3 swells greatly in a trumpet shape as shown in FIG. Of course, it also expands as a whole, increasing its inner and outer diameters.

FIGS. 8 and 9 show a fourth embodiment of the present invention. This embodiment relates to a drainage tube 1 like the above-mentioned embodiments, but the portion 3 that increases the proportion of highly water-absorbent material mixed is located only at one end of the tube body 2. Furthermore, cuts 11 are made in this portion 3 to form a large number of pieces 12. Therefore, when it absorbs water and expands, the portion 3 expands into a number of pieces 12 as shown in FIG. 9. Therefore, it can be expanded greatly. Other structures and operations are similar to those of the above embodiment. In addition, if the cut 11 is a slit with a gap as shown in FIG. 10, the surface area becomes large and the engraving speed can be increased.

In addition, the in-vivo indwelling device of the present invention may be made by making the part 3 in which the content of the superabsorbent material is partially different from other parts, and by connecting these parts. .

Below are examples of disclosures. The disclosed example shown in FIGS. 11 and 12 is an example of a drainage tube 21 that is endoscopically inserted into a bile duct and left therein.

The tube body 22 of the drainage tube 21 is made of a biocompatible material and is formed into a cylindrical shape having an equal diameter over its entire length. This material is based on, for example, a resin such as silicone elastomer, polyurethane elastomer, or ethylene vinyl alcohol (EVA). The portions 23 and 23 at both ends of the tube body 22 are mixed with a highly absorbent resin as a highly absorbent material as described above. Note that the above portions 23 and 23 are connected to the tube body 2.
It may be made separately from 2.

When this is indwelled in a living body, only the portion 23° 23 absorbs water and expands, expanding into a trumpet shape as shown in FIG.

The disclosed example shown in FIGS. 13 and 14 relates to the drainage tube 21 similarly to the first disclosed example, but the portions 23 and 23 made of a highly absorbent material are located between both ends of the tube body 22. It was placed on the side. The rest is the same as that of the first disclosed example.

The portion 23 formed by mixing the super absorbent material in this way.
23 is arranged closer to the middle portion, when it absorbs water and expands, it swells into a rounded mountain shape as shown in FIG. 14. Of course, it also expands as a whole, increasing its inner and outer diameters.

The disclosed example shown in FIGS. 15 and 16 relates to a drainage tube 21 similar to each of the above-mentioned disclosed examples, but the portion 23 in which the proportion of highly absorbent material mixed is increased is at one end of the tube body 22. It was formed only in

The disclosed example shown in FIG. 17 relates to a drainage tube 21 similar to the above-mentioned disclosed examples, but the outer surface of the portion 23 in which the proportion of superabsorbent material mixed is increased is roughened.

The disclosed example shown in FIGS. 18 to 19 relates to a drainage tube 21 like the above-mentioned respective disclosed examples, but has a notch 24 formed in a portion 23 formed of a highly absorbent material. For this reason, it is greatly expanded as shown in FIG. Further, as shown in FIG. 20, the notch 24 may be a slit.

In the disclosed example shown in FIG. 21, a band-shaped member 27.27 made of a highly absorbent material is attached to the outer periphery of a tube 26, and when this in-vivo indwelling device is inserted into a living body, the member 27.
7.27 absorbs water and expands, functioning as a balloon (double balloon). Further, the tube 26 has a closed end and a hole 26a formed in the middle thereof.

In the disclosed example shown in FIG. 22, a separate cylindrical member 28 made of a highly absorbent material is connected to one end of the tube body 22. When this in-vivo indwelling device is inserted into the living body, the member 28 is connected to one end of the tube body 22. A balloon that absorbs water and expands (double balloon)
It is designed to function as a

In the disclosed example shown in FIG. 23, a strip-shaped balloon member 29 made of a highly absorbent material is attached to the outer periphery of a tube 26, and a water supply catheter 30 is connected to the inside of this balloon member 29 so that water can be supplied. It is something. Balloon member 2
By supplying water to the balloon 9, the balloon member 29 is inflated by water pressure and also expanded by water absorption.

In the disclosed example shown in FIGS. 23 and 24, the intermediate portion of the tube body 22 of the in-vivo indwelling device is constructed with a cylindrical member 31 made of a highly water-absorbing material. Therefore, when this member is placed in a living body, the member 31 absorbs water and expands, as shown in FIG. 25. Functions as a balloon. Furthermore, in this disclosed example, a plurality of protrusions 32 are provided on the outer circumferential surface of the member 31 so that the member 31 is caught on the body cavity wall when indwelled in the body.

Although the above embodiments and disclosed examples have been explained using a drainage tube as an example, the present invention is not limited to this, and can also be used, for example, in an esophageal prosthesis (esophageal tube) inserted into a site of esophageal stricture, and in other cases, for example. It can be applied to a biological duct dilator that is placed in a constricted site of a biological duct such as a blood vessel or urethra to expand the duct. Furthermore, the form of the indwelling device main body can also be changed depending on the insertion and indwelling site. Alternatively, it may be introduced transdermally.

[Effects of the Invention] As explained above, according to the present invention, when this is placed at a target site within a living body, the super absorbent material absorbs water and expands. By partially varying the expansion rate, it is reliably transformed into a form that is optimally equipped with expansion action, removal prevention action, unnecessary movement prevention action, etc. Moreover, it is possible to provide an in-vivo indwelling device that has a simple configuration, is easy to insert into an in-vivo site, and is highly safe because it gradually self-expands without causing damage to living tissue.

[Brief explanation of the drawing]

1 to 3 show a first embodiment of the present invention, and FIG. 1 is a partially cutaway side sectional view of the in-vivo indwelling device;
FIG. 2 is a partially cutaway side sectional view of the expanded in-vivo indwelling device, and FIG. 3 is an explanatory diagram of the state in which the in-vivo indwelling device is used. 4 and 7 show a second embodiment of the present invention, FIG. 4 is a partially cutaway side sectional view of the in-vivo indwelling device, and FIG. 5 is an inflated in-vivo indwelling device. FIG. 2 is a partially cutaway side sectional view. FIG. 6 and FIG. 7 are the third embodiment of the present invention.
FIG. 6 is a partially cut-away side sectional view of the in-vivo indwelling device, and FIG. 7 is a partially cut-away side sectional view of the inflated in-vivo indwelling device. FIGS. 8 and 9 show a fourth embodiment of the present invention, with FIG. 8 being a side view of the in-vivo indwelling device, and FIG. 9 being a side view of the inflated in-vivo indwelling device. FIGS. 11 and 12 show examples of disclosure, and FIGS.
The figure is a side view of the in-vivo indwelling device, and FIG. 12 is a side view of the inflated in-vivo indwelling device. 13 and 14 show a disclosed example, and FIG. 13 is a side view of the in-vivo indwelling device,
FIG. 14 is a side view of the inflated in-vivo indwelling device. 1st
5 and 16 show the disclosed example, FIG. 15 is a side view of the in-vivo indwelling device, and FIG. 16 is a side view of the inflated in-vivo indwelling device. FIG. 17 is a side view of the in-vivo indwelling device showing the disclosed example. FIGS. 18 and 19 show disclosed examples, with FIG. 18 being a side view of the indwelling device, and FIG. 19 being a side view of the inflated indwelling device. FIG. 20 is a side view of the in-vivo indwelling device of the disclosed example. FIG. 21 is a partially cutaway side view of the in-vivo indwelling device of the disclosed example. FIG. 22 is a partially cutaway side view of the in-vivo indwelling device of the disclosed example. FIG. 23 is a partially cutaway side view of the in-vivo indwelling device of the disclosed example. 24 and 25 show a disclosed example, FIG. 24 is a partially cut-away side view of the in-vivo indwelling device, and FIG. 25 is a partially cut-away side view of the inflated in-vivo indwelling device. FIG. DESCRIPTION OF SYMBOLS 1...Drainage tube, 2...Tube body, 3...Part, 5...Bile duct, 6...Stricture site.

Claims (1)

[Claims] An in-vivo indwelling device that is introduced into an in-vivo site and indwelled therein, in which a highly water-absorbing material is mixed to form the indwelling device body, and the content of the super-absorbent material is partially varied. An in-vivo indwelling device characterized by: