JPH03212269A - Check valve for blood circuit - Google Patents
Check valve for blood circuitInfo
- Publication number
- JPH03212269A JPH03212269A JP2007297A JP729790A JPH03212269A JP H03212269 A JPH03212269 A JP H03212269A JP 2007297 A JP2007297 A JP 2007297A JP 729790 A JP729790 A JP 729790A JP H03212269 A JPH03212269 A JP H03212269A
- Authority
- JP
- Japan
- Prior art keywords
- tubular member
- check valve
- blood
- cylindrical housing
- blood circuit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008280 blood Substances 0.000 title claims abstract description 33
- 210000004369 blood Anatomy 0.000 title claims abstract description 33
- 239000007788 liquid Substances 0.000 abstract description 14
- 208000007536 Thrombosis Diseases 0.000 abstract description 10
- 239000012503 blood component Substances 0.000 abstract description 2
- 230000005484 gravity Effects 0.000 description 9
- 230000015572 biosynthetic process Effects 0.000 description 7
- 239000000463 material Substances 0.000 description 7
- 239000000853 adhesive Substances 0.000 description 6
- 230000001070 adhesive effect Effects 0.000 description 6
- -1 MS) Polymers 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 229920001971 elastomer Polymers 0.000 description 5
- 229920002635 polyurethane Polymers 0.000 description 5
- 239000004814 polyurethane Substances 0.000 description 5
- 230000002785 anti-thrombosis Effects 0.000 description 4
- 239000003146 anticoagulant agent Substances 0.000 description 4
- 239000000806 elastomer Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- 239000011148 porous material Substances 0.000 description 3
- 229920005989 resin Polymers 0.000 description 3
- 239000011347 resin Substances 0.000 description 3
- 239000004698 Polyethylene Substances 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 239000004793 Polystyrene Substances 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- MCMNRKCIXSYSNV-UHFFFAOYSA-N Zirconium dioxide Chemical compound O=[Zr]=O MCMNRKCIXSYSNV-UHFFFAOYSA-N 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 230000003205 diastolic effect Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 229920000515 polycarbonate Polymers 0.000 description 2
- 239000004417 polycarbonate Substances 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 229920000098 polyolefin Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 229920002223 polystyrene Polymers 0.000 description 2
- 230000000541 pulsatile effect Effects 0.000 description 2
- 229920002379 silicone rubber Polymers 0.000 description 2
- 239000004945 silicone rubber Substances 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 239000011147 inorganic material Substances 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 229920005597 polymer membrane Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920003225 polyurethane elastomer Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 229920000468 styrene butadiene styrene block copolymer Polymers 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Landscapes
- External Artificial Organs (AREA)
- Prostheses (AREA)
Abstract
Description
【発明の詳細な説明】
［産業上の利用分野］
本発明は、主として血液等の生物学的流体を搬送する流
体回路中に配設される逆止弁に関する。特に、本発明は
、弁体として球体（ボール）を用いたボール弁型逆止弁
に関する。DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to a check valve disposed in a fluid circuit that primarily transports biological fluids such as blood. In particular, the present invention relates to a ball valve type check valve using a sphere (ball) as a valve body.
［従来技術］
最近実用化が進んでいる補助心臓等に使用可能な血液ポ
ンプ用の逆止弁としては、はとんどの例でＢｊｏｒｋ−
８ｈｉ ｌｅｙ弁等の弁置換術用人工弁が一般的に流用
されている。[Prior Art] Most of the check valves for blood pumps that can be used in auxiliary hearts, etc., which have recently been put into practical use, are Bjork-
Artificial valves for valve replacement, such as the 8hi ley valve, are commonly used.
そして、最近では、高分子製の簡易な逆止弁の開発が行
われている。このような簡易な逆止弁としては、ポリウ
レタンなどの高分子膜を用いて生体の三葉弁を模倣した
タイプ、さらには、ボール弁タイプのものが知られてい
る。Recently, simple check valves made of polymers have been developed. As such simple check valves, there are known types that imitate biological three-leaf valves using polymer membranes such as polyurethane, and ball valve types.
さらに、最近では、工業的に生産しやすいため、ボール
弁タイプの逆止弁の使用が検討されて来ている。Furthermore, recently, the use of ball valve type check valves has been considered because they are easy to produce industrially.
そして、このボール弁タイプの逆止弁では管路径より大
きなボールを管路中に挿入する必要があるが、そのため
の構成として、以下のものがある。In this ball valve type check valve, it is necessary to insert a ball larger than the pipe diameter into the pipe, and the following configurations are available for this purpose.
例えば、特開昭６３−２４６１７４号公報に示されてい
るように、ハウジングを２ピース構造とし、ボールを挿
入した後に接着、ネジ止め等の手段でハウジングを固定
したもの、また、特開昭６２−１５９６４８号公報に示
されているように、ハウジングを１ピースで成形し、ハ
ウジング内でボールを成形したものなどがある。For example, as shown in Japanese Unexamined Patent Publication No. 63-246174, the housing has a two-piece structure, and after inserting a ball, the housing is fixed by adhesives, screws, etc.; As shown in Japanese Patent No. 159648, there is one in which the housing is molded in one piece and a ball is molded within the housing.
［発明が解決しようとする問題点コ
しかし、上記の弁置換術用人工弁は高価であり、さらに
、これら人工弁は、生体の血管に取り付けるように設計
されており、液体ポンプに用いると、弁軸固定部の血栓
形成、衝撃現象による弁体の破壊等の問題点を有してい
る。[Problems to be Solved by the Invention] However, the above-mentioned artificial valves for valve replacement surgery are expensive, and furthermore, these artificial valves are designed to be attached to a living blood vessel, and when used in a liquid pump, There are problems such as thrombus formation at the valve stem fixation part and destruction of the valve body due to impact phenomena.
そして、上記のポリウレタン等のエラストマーを使用し
た三葉弁では、エラストマーの劣化か生じるため、信頼
性と、耐久性に欠けるという欠点がある。The three-lobed valve using an elastomer such as polyurethane has the drawback of lacking reliability and durability due to deterioration of the elastomer.
さらに、上述のハウジングを１ピースで成形し、ハウジ
ング内でボールを成形したものでは、ハウジング内での
ボールの成形に時間がかかること、またボールの成形精
度に問題があるという欠点を有している。よって、ハウ
ジングを２ピース構造とし、ボールを挿入した後に接着
、ネジ止め等の手段でハウジングを固定するものが工業
的に最も単純であり、量産性に優れているが、ハウジン
グの内側に現れる継目の部分での血栓形成という問題が
ある。特に、２つ部材を接着のみにて接合する場合は、
接合面に適切な締め付は力をかけることが難しく、ハウ
ジング内側の継目部分に隙間があきやすく、血栓形成を
増進させるという問題がある。Furthermore, when the housing is molded in one piece and the ball is molded inside the housing, it takes time to mold the ball inside the housing, and there are problems with the accuracy of the ball molding. There is. Therefore, it is industrially simplest to have a two-piece housing and fix the housing by adhesives, screws, etc. after inserting the ball, and it is excellent for mass production, but the seams that appear on the inside of the housing There is a problem of thrombus formation in the area. In particular, when joining two parts using only adhesive,
There is a problem in that it is difficult to apply force to properly tighten the joint surfaces, and gaps tend to form at the joints inside the housing, promoting thrombus formation.
そこで、本発明の目的は、上記の問題点を解決し、２つ
の部材を接合することによりハウジングが形成されるた
め製造が容易で、かつ、２つの部材の接合部分での血栓
形成が少ないボール弁型の血液回路用逆止弁を提供する
ことにある。SUMMARY OF THE INVENTION Therefore, an object of the present invention is to solve the above-mentioned problems, and to provide a ball that is easy to manufacture because the housing is formed by joining two members, and that there is less thrombus formation at the joining part of the two members. An object of the present invention is to provide a valve-type check valve for a blood circuit.
［問題点を解決するための手段］
本発明は、中央に拡径部を有する筒状ハウジングと、該
筒状ハウジングの前記拡径部内に移動可能に収納された
球体とからなる血液回路用逆止弁であって、前記筒状ハ
ウジングは、第１管状部材と、該第１管状部材と嵌合す
る第２管状部材とからなり、そして、前記第１管状部材
と該第２管状部材との接合面はそれぞれ対応したテーパ
ー面となっている血液回路用逆止弁である。[Means for Solving the Problems] The present invention provides a blood circuit inverter comprising a cylindrical housing having an enlarged diameter portion in the center and a sphere movably housed within the enlarged diameter portion of the cylindrical housing. In the stop valve, the cylindrical housing includes a first tubular member and a second tubular member that fits into the first tubular member, and the first tubular member and the second tubular member are connected to each other. The joint surfaces are check valves for blood circuits each having a corresponding tapered surface.
そして、前記血液回路用逆止弁は、第１のネジ部を備え
た環状部材を有し、前記第１管状部材もしくは第２管状
部材のいずれか一方には、前記環状部材が有する第１の
ネジ部と螺合する第２のネジ部を有し、該第１のネジ部
と第２のネジ部とが螺合することにより、前記第１管状
部材と第２管状部材の接合面を抑圧可能としてでいるも
のが好ましい。さらに、前記第１管状部材または前記第
２管状部材のいずれか一方は、嵌合部・に突起を有し、
前記第１管状部材または前記第２管状部材の他方は、前
記突起に対応した凹部を有していることが好ましい。The blood circuit check valve includes an annular member having a first threaded portion, and either the first tubular member or the second tubular member has a first thread included in the annular member. It has a second threaded part that is threaded into the threaded part, and the first threaded part and the second threaded part are threaded together to suppress the joint surface between the first tubular member and the second tubular member. Preferably, it is possible. Furthermore, either the first tubular member or the second tubular member has a protrusion at the fitting portion,
Preferably, the other of the first tubular member and the second tubular member has a recess corresponding to the protrusion.
そこで、本発明の血液回路用逆止弁を図面に示した実施
例を用いて説明する。Therefore, the blood circuit check valve of the present invention will be explained using an embodiment shown in the drawings.
第１図は、本発明の逆止弁の実施例の断面図であり、第
２図は、第１図のＡ−Ａ線断面図である。FIG. 1 is a sectional view of an embodiment of the check valve of the present invention, and FIG. 2 is a sectional view taken along the line A--A in FIG.
この逆止弁１は、中央に拡径部８を有する筒状ハウジン
グ２と、筒状ハウジング２の拡径部８内に移動可能に収
納された球体３とからなる血液回路用逆止弁であり、筒
状ハウジング２は、第１管状部材２ａと、この第１管状
部材２ａと嵌合する第２管状部材２ｂとからなり、そし
て、第１管状部材２ａと第２管状部材２ｂとの接合面８
ｃ、３ｄはそれぞれ対応したテーパー面となっている。This check valve 1 is a blood circuit check valve consisting of a cylindrical housing 2 having an enlarged diameter part 8 in the center, and a sphere 3 movably housed within the enlarged diameter part 8 of the cylindrical housing 2. The cylindrical housing 2 consists of a first tubular member 2a and a second tubular member 2b that fits into the first tubular member 2a, and the first tubular member 2a and the second tubular member 2b are joined together. Face 8
c and 3d are respectively corresponding tapered surfaces.
そこで、図面を参照して説明する。Therefore, description will be given with reference to the drawings.
この実施例の逆止弁１は、第１管状部材２ａと第２管状
部材２ｂとにより形成された筒状ハウジング２と、この
ハウジング２の拡径部８の内部に収納された球体３とか
らなっている。The check valve 1 of this embodiment includes a cylindrical housing 2 formed by a first tubular member 2a and a second tubular member 2b, and a spherical body 3 housed inside an enlarged diameter portion 8 of this housing 2. It has become.
第１管状部材２ａは、第１図に示すように、一端に液体
流入口４を有しており、他端は、拡径部８ａとなってい
る。同様に、第２管状部材２ｂは、第１図に示すように
、一端に液体流出口５を有して、他端は拡径部８ｂとな
っている。As shown in FIG. 1, the first tubular member 2a has a liquid inlet 4 at one end, and an enlarged diameter portion 8a at the other end. Similarly, the second tubular member 2b has a liquid outlet 5 at one end and an enlarged diameter portion 8b at the other end, as shown in FIG.
そして、第１管状部材２ａの液体流入口部分および第２
管状部材２ｂの液体流出口部分は、端部に向かって拡径
するテーパー状にすることが好ましく、このようにする
ことにより、ポンプチューブ、液体チューブ、カニユー
レなどとの接続部の実質的な段差を少なくすることがで
き血栓の発生を抑制できる。The liquid inlet portion of the first tubular member 2a and the second
It is preferable that the liquid outlet portion of the tubular member 2b has a tapered shape that increases in diameter toward the end, and by doing so, there is no substantial step difference in the connection portion with the pump tube, liquid tube, cannula, etc. It is possible to reduce the occurrence of blood clots and to suppress the occurrence of blood clots.
そして、第１管状部材２ａと第２管状部材２ｂは、それ
らの拡径部８ａと８ｂとが嵌合することにより接合され
ている。The first tubular member 2a and the second tubular member 2b are joined by fitting their enlarged diameter portions 8a and 8b.
さらに、第１管状部材２ａの拡径部８ａと第２管状部材
２ｂの拡径部８ｂとの接合面８Ｃ１８ｄは、ともに対応
した（はぼ同角度の）テーパー面となりいる。このよう
に接合面８ｃ、 ８ｄをほぼ同角度のテーパー状に成
形することにより、第１管状部材２ａと第２管状部材２
ｂを嵌合させ、さらに押圧したとき、両者の接合面８ｃ
、 ８ｄにおいてくさび効果が生じ、通常の平行面接
合に比べ、より緊密に固定される。そして、好ましくは
、第１管状部材２ａと第２管状部材２ｂとの接合部分の
拡大断面図である第３図に示すように、第２管状部材２
ｂの凸状のテーパー面８ｄの先端部の内径ＤＩは、第１
管状部材２ａの凹状のテーパー面８Ｃの内径Ｄ２と同じ
あるいは若干小さく成形されていること（ＤＩ≧Ｄ２）
が好ましく、このようにすることにより、拡径部８の内
部に微少な突起が形成されることがなく好ましい。つま
り、血液流（血液流入口４→血液流出口５）が直接当接
する部分が第１管状部材２ｂと第２管状部材２ｂとの接
合面に形成されないことが好ましい。さらに、第１図に
示す実施例では、第１管状部材２ｂの拡径部８ｃの内面
側端部のテーパー角度が大きく、第２管状部材２ｂの拡
径部８ｄの内面側端部のテーパー角が小さく形成されて
おり、両者を接合するとほぼ接合端が直線上になるよう
に成形されている。両者の形状は、第１図に示すものに
限られず逆にしてもよい。最も好ましくは、第１図に示
すように、第２管状部材２ａの拡径部８ｄのを鋭角なテ
ーパーを有する端部とし、上述のように、この拡径部８
ｄの端部の内径を第１管状部材２ａの拡径部８ｃの端部
の内径を等しいか若干小さくすることである。この形状
が最も血栓発生を抑制できるものと考える。Further, the joint surfaces 8C18d between the enlarged diameter portion 8a of the first tubular member 2a and the enlarged diameter portion 8b of the second tubular member 2b are tapered surfaces that correspond to each other (at approximately the same angle). By forming the joining surfaces 8c and 8d into a tapered shape having approximately the same angle in this way, the first tubular member 2a and the second tubular member 2
When b is fitted and further pressed, the joint surface 8c of both
, 8d, a wedge effect occurs and the bond is more tightly fixed than a normal parallel surface connection. Preferably, the second tubular member 2
The inner diameter DI of the tip of the convex tapered surface 8d of b is the first
Shaped to be the same as or slightly smaller than the inner diameter D2 of the concave tapered surface 8C of the tubular member 2a (DI≧D2)
is preferable, and by doing so, minute protrusions are not formed inside the enlarged diameter portion 8, which is preferable. In other words, it is preferable that a portion where the blood flow (blood inlet 4 → blood outlet 5) directly contacts is not formed on the joint surface of the first tubular member 2b and the second tubular member 2b. Furthermore, in the embodiment shown in FIG. 1, the taper angle of the inner side end of the enlarged diameter part 8c of the first tubular member 2b is large, and the taper angle of the inner side end of the enlarged diameter part 8d of the second tubular member 2b is large. is formed small, and when the two are joined, the joined ends are formed on a substantially straight line. The shapes of both are not limited to those shown in FIG. 1, and may be reversed. Most preferably, as shown in FIG. 1, the enlarged diameter portion 8d of the second tubular member 2a has an acutely tapered end, and as described above, the enlarged diameter portion 8d
The inner diameter of the end portion d is equal to or slightly smaller than the inner diameter of the end portion of the enlarged diameter portion 8c of the first tubular member 2a. We believe that this shape can best suppress thrombus formation.
さらに、第１図に示す実施例の逆止弁１は、第１のネジ
部１６を備えた環状部材１２を有し、第１管状部材２ａ
もしくは第２管状部材２ｂいずれか一方（第１図に示す
実施例では、第１管状部材２ａ）には、環状部材１２が
有する第１のネジ部１６と螺合する第２のネジ部１７を
有し、第１のネジ部１６と第２のネジ部１７の螺合によ
り、第１管状部材２ａと第２管状部材２ｂの接合面が押
圧され、固定されている。このように構成することによ
り、第１管状部材２ａと第２管状部材２ｂの接合面８ｃ
と８ｄが、嵌合作業時に擦れ合うことがなく、よって、
内面に微少な傷が生ずることを抑制できる。Furthermore, the check valve 1 of the embodiment shown in FIG.
Alternatively, one of the second tubular members 2b (in the embodiment shown in FIG. 1, the first tubular member 2a) has a second threaded portion 17 that is threadedly engaged with the first threaded portion 16 of the annular member 12. By screwing the first threaded part 16 and the second threaded part 17, the joint surfaces of the first tubular member 2a and the second tubular member 2b are pressed and fixed. With this configuration, the joint surface 8c between the first tubular member 2a and the second tubular member 2b
and 8d do not rub against each other during the mating process, so
It is possible to suppress the occurrence of minute scratches on the inner surface.
さらに、第８図および第８図のＤ−Ｄ断面図である第９
図に示すように、第１管状部材２ａまたは第２管状部材
２ｂのいずれか一方（第８図に示す実施例では、第１管
状部材２ａ）は、嵌合部に突起２０を有し、第１管状部
材２ａまたは第２管状部材２ｂの他方（第８図に示す実
施例では、第２管状部材２ｂ）は、突起２０に対応した
凹部２１を設けることが好ましく、このようにすること
により、両部材の接合作業時の相対的回転を抑制し、相
対回転による接合面の擦れ合いに起因する微少な傷の発
生を抑制する。こ０
のような回り止め構造は最小限−ケ所あればよい。また
、第１管状部材２ａと第２管状部材２ｂとの固定は、第
６図および第６図のＣ−Ｃ線断面図である第７図に示す
ように、複数（例えば、６本）のボルト１０を用い、第
１管状部材２ａもしくは第２管状部材２ｂのいずれかの
拡径部３ａ、３ｂに球体３を保持させた状態で、他方管
状部材を一方の管状部材に嵌合させ、第１管状部材のフ
ランジもしくは第２管状部材のフランジのいずれかに（
第６図および第７図に示す実施例では、第２管状部材２
ｂ）軸対称の位置に複数に設けられた雌ネジ部にボルト
１０を螺合させることにより行われる。そして、第１管
状部材２ａの嵌合面８Ｃと第２管状部材の嵌合面８ｄは
、はぼ対応した同角度のテーパー状に成形されているた
め、くさび効果が生じ、通常の平行面嵌合に比べ、より
緊密に固定される。Furthermore, FIG. 8 and FIG.
As shown in the figure, either the first tubular member 2a or the second tubular member 2b (in the embodiment shown in FIG. 8, the first tubular member 2a) has a protrusion 20 at the fitting part, and The other of the first tubular member 2a and the second tubular member 2b (in the embodiment shown in FIG. 8, the second tubular member 2b) is preferably provided with a recess 21 corresponding to the protrusion 20, and by doing so, It suppresses relative rotation during the joining work of both members, and suppresses the occurrence of minute scratches caused by rubbing of the joint surfaces due to relative rotation. A minimum number of anti-rotation structures like this are sufficient. Further, the first tubular member 2a and the second tubular member 2b are fixed by a plurality of (for example, six) Using bolts 10, with the sphere 3 held in the expanded diameter portions 3a and 3b of either the first tubular member 2a or the second tubular member 2b, fit the other tubular member into one tubular member, and then Either the flange of the first tubular member or the flange of the second tubular member (
In the embodiment shown in FIGS. 6 and 7, the second tubular member 2
b) This is carried out by screwing the bolt 10 into a plurality of female screw portions provided at axially symmetrical positions. Since the fitting surface 8C of the first tubular member 2a and the fitting surface 8d of the second tubular member are formed into tapered shapes with the same angle corresponding to each other, a wedge effect occurs, and the fitting surface 8d of the second tubular member 2a has a wedge effect. It is fixed more tightly than when
そして、第２管状部材２ｂの上面図である第４図および
第４図のＢ−Ｂ断面図である第５図に示すように、第２
管状部材２ｂの拡径部８ｂの内面には、拡径部８ｂの開
口端部付近より液体流出口５方向に延び、拡径部８ｂの
終了端部付近に至る突出部６を有している。突出部６は
、３つ以上、好ましくは、３つ、第２管状部材２ｂの軸
方向と平行に設けられていることが好ましい。そして、
突出部６の端部６ａは、第５図に示すように、拡径部内
面と溝などを形成することなくなだらかに形成されてい
ることが好ましい。また、突出部６の他端部には、第１
図および第５図に示すように、球体３の係止部７が設け
られている。そして、第４図に示すように、突出部６は
、拡径部８ｂの内面にほぼ等間隔離間した距離に設けら
れている。さらに、突出部６の先端が規定する円（３つ
の先端が接する円）の半径は、球体３の半径より若干大
きいかほぼ等しいものとなっており、また、突出部６に
設けられた係止部７の先端が規定する円（係止部７の３
つの先端が接する円）の半径は、球体３の半径より若干
小さいものとなっている。そして、第１管状部材２ａの
拡径部８ａの体内流入口側の内面はほぼ円錐状に形成さ
れており、第１図に示すように、球体３と接触したとき
液密状態に密着可能な形状となっている。つまり、接触
部９の内面が形成する円形断面がその部分に当接する球
体３の外面（第１図において点線にて示す）形状とほぼ
合致している。これにより、液体流出口５側が陽圧とな
ったとき、球体３がこの拡径部８ａのほぼ円錐状の内面
である接触部９ａに接触した状態で密着し、液体の流通
を阻止する。As shown in FIG. 4, which is a top view of the second tubular member 2b, and FIG. 5, which is a sectional view taken along line BB in FIG.
The inner surface of the enlarged diameter portion 8b of the tubular member 2b has a protrusion 6 that extends in the direction of the liquid outlet 5 from near the open end of the enlarged diameter portion 8b and reaches near the end end of the enlarged diameter portion 8b. . It is preferable that three or more, preferably three, protrusions 6 are provided parallel to the axial direction of the second tubular member 2b. and,
As shown in FIG. 5, the end portion 6a of the protruding portion 6 is preferably formed smoothly without forming a groove or the like with the inner surface of the enlarged diameter portion. Further, at the other end of the protrusion 6, a first
As shown in the figure and FIG. 5, a locking portion 7 for the sphere 3 is provided. As shown in FIG. 4, the protrusions 6 are provided on the inner surface of the enlarged diameter portion 8b at approximately equal intervals. Furthermore, the radius of the circle defined by the tips of the protrusion 6 (the circle where the three tips touch) is slightly larger than or almost equal to the radius of the sphere 3, and The circle defined by the tip of part 7 (3 of locking part 7)
The radius of the circle (which the two tips touch) is slightly smaller than the radius of the sphere 3. The inner surface of the enlarged diameter portion 8a of the first tubular member 2a on the body inflow port side is formed into a substantially conical shape, and as shown in FIG. It has a shape. That is, the circular cross section formed by the inner surface of the contact portion 9 substantially matches the shape of the outer surface (indicated by a dotted line in FIG. 1) of the sphere 3 that comes into contact with that portion. As a result, when a positive pressure is applied to the liquid outlet 5 side, the sphere 3 comes into close contact with the contact portion 9a, which is the substantially conical inner surface of the enlarged diameter portion 8a, and blocks the flow of liquid.
よって、球体３は、ハウジングの拡径部を拡径部の接触
部９から係止部７に当接するまで移動可能であり、ハウ
ジング２内部を開閉し、弁体として機能する。Therefore, the sphere 3 can move the enlarged diameter portion of the housing from the contact portion 9 of the enlarged diameter portion until it abuts the locking portion 7, opens and closes the inside of the housing 2, and functions as a valve body.
そして、第１管状部材２ａおよび第２管状部材２ｂは、
ポリカーボネート、スチレン系樹脂（例えば、ポリスチ
レン、ＭＢＳ、ＭＳ） 、ポリオレフィン（例えば、ポ
リプロピレン、ポリエチレン）、塩化ビニル樹脂、ポリ
ウレタン、ポリウレタンエラストマー シリコーンゴム
な３
どにより形成される。The first tubular member 2a and the second tubular member 2b are
It is formed from polycarbonate, styrene resin (eg, polystyrene, MBS, MS), polyolefin (eg, polypropylene, polyethylene), vinyl chloride resin, polyurethane, polyurethane elastomer, silicone rubber, etc.
また、球体３は、断面がほぼ真円形を有する球体であり
、上述のように、拡径部８の接触部９の内径および係止
部７の規定する円の内径より大きい直径を有している。Further, the sphere 3 is a sphere having a substantially perfect circular cross section, and has a diameter larger than the inner diameter of the contact portion 9 of the enlarged diameter portion 8 and the inner diameter of the circle defined by the locking portion 7, as described above. There is.
球体３は、ポリウレタン、シリコーンゴム、ＳＢＳエラ
ストマー、ラテックスゴムなどのゴム材またはエラスト
マー、また、ポリオレフィン（例えば、ポリプロピレン
、ポリエチレン）、ポリカーボネイト、ポリスチレンな
どの合成樹脂、さらには、ジルコニア、アルミナ、シリ
カなどの無機材料などにより形成される。The sphere 3 is made of rubber material or elastomer such as polyurethane, silicone rubber, SBS elastomer, latex rubber, synthetic resin such as polyolefin (for example, polypropylene, polyethylene), polycarbonate, polystyrene, and furthermore, zirconia, alumina, silica, etc. It is formed from inorganic materials.
好ましくは、球体３は、逆止弁が用いられる流体（例え
ば血液）の比重と同程度（液体の比重の０．７〜１．５
倍程度）とすることである。このようにすることにより
、逆止弁の設置方向により球体が浮力による影響を受け
、動作特性が著しく変化することを防止でき好ましい。Preferably, the sphere 3 has a specific gravity similar to that of the fluid (for example blood) in which the check valve is used (0.7 to 1.5 of the specific gravity of the liquid).
(approximately twice as much). By doing so, it is possible to prevent the sphere from being influenced by buoyancy depending on the direction in which the check valve is installed, thereby preventing the operating characteristics from changing significantly.
このような比重を有する球体は、目的とする比重を有す
る材料により形成する方法、また使用する材料、＝１４
−
例えば樹脂が目的とする比重より軽い場合は、比重調整
剤（例えば金属粉末）を混入させる方法、また逆に使用
する材料が比重が目的とする比重より大きい場合は、球
体を中空体に形成する方法などが考えられる。そして、
ハウジング２の拡径部８以外の部分（管路部分）の内径
は、成人用血液ポンプに使用する場合８〜２０■程度が
一般的であり、新生児用血液ポンプに使用する場合は、
３屑屑程度が一般的である。また、球体３の直径は、管
路部分の１．１〜１７倍程度が好ましい。そして、突出
部６の先端が規定する円の直径と、球体３の直径との差
は、０．１〜０，４■が好ましい。A sphere having such a specific gravity can be formed by a method of forming it from a material having a desired specific gravity, and a material used: =14
- For example, if the specific gravity of the resin is lighter than the desired specific gravity, there is a method of mixing a specific gravity adjusting agent (e.g. metal powder), or conversely, if the specific gravity of the material used is higher than the desired specific gravity, forming a sphere into a hollow body. There are ways to do this. and,
The inner diameter of the part of the housing 2 other than the enlarged diameter part 8 (pipe line part) is generally about 8 to 20 mm when used in an adult blood pump, and when used in a neonatal blood pump.
Generally, there are about 3 pieces of waste. Moreover, the diameter of the sphere 3 is preferably about 1.1 to 17 times that of the pipe portion. The difference between the diameter of the circle defined by the tip of the protrusion 6 and the diameter of the sphere 3 is preferably 0.1 to 0.4 square centimeters.
さらに、ハウジング２の内面には、抗血栓材料をコーテ
ィングすることが好ましい。Furthermore, the inner surface of the housing 2 is preferably coated with an antithrombotic material.
抗血栓材料としては、セグメント化ポリウレタン、ポリ
ＨＥＭＡ、ＨＥＭＡ−スチレンブロックポリマー、ＨＥ
ＭＡ−３ｔ−ＨＥＭＡブロックコポリマー、シリコーン
などが使用できる。Antithrombotic materials include segmented polyurethane, polyHEMA, HEMA-styrene block polymer, HE
MA-3t-HEMA block copolymer, silicone, etc. can be used.
また、ヘパリン等の抗血栓物質を内表面に固定してもよ
い。同様に、球体３の表面にも上記のような抗血栓材料
をコーティングあるいは固定することが好ましい。Additionally, antithrombotic substances such as heparin may be immobilized on the inner surface. Similarly, it is preferable that the surface of the sphere 3 is also coated or fixed with the above-mentioned antithrombotic material.
また、第１０図および第１１図に示すように、第１管状
部材２ａまたは第２管状部材２ｂの嵌合面付近さらには
、環状部材１２に接着剤注入用の細孔１４を設けてもよ
い。この細孔１４を設けることにより、第１管状部材２
ａと第２管状部材２ｂさらには環状部材３を取り付けた
後、上記細孔１４より接着剤を注入することができ、注
入された接着剤は、ハウジング２の内面に流出すること
がない。Further, as shown in FIGS. 10 and 11, a pore 14 for adhesive injection may be provided in the annular member 12 near the fitting surface of the first tubular member 2a or the second tubular member 2b. . By providing this pore 14, the first tubular member 2
After attaching the second tubular member 2a, the second tubular member 2b, and the annular member 3, the adhesive can be injected through the pore 14, and the injected adhesive will not flow out to the inner surface of the housing 2.
次に、本発明の逆止弁１を用いた血液回路について説明
する。Next, a blood circuit using the check valve 1 of the present invention will be explained.
第１２図に示すものは、上述′の逆止弁１を内蔵するコ
ネクタ５１を遠心式血液ポンプ５２と熱交換器付人工肺
５３との間に取り付けた関心術などにに使用される体外
循環用血液回路５０であり、５６は脱血カニユーレ、５
７は送血カニユーレ、５５はポンプ制御装置、５４は流
量計プローブである。The one shown in FIG. 12 is an extracorporeal circulation system used for surgical procedures, etc., in which a connector 51 incorporating the above-mentioned check valve 1 is attached between a centrifugal blood pump 52 and an oxygenator with a heat exchanger 53. 56 is a blood removal cannula;
7 is a blood feeding cannula, 55 is a pump control device, and 54 is a flowmeter probe.
また、第１３図に示す血液回路５０は、逆止弁一体型血
液ポンプ５２を取り付けたものであり、また、第１４図
に示す血液回路５０は、逆止弁内蔵送血カニユーレ５７
を取り付けたものであり、第１５図に示すものは、逆止
弁内蔵脱血カニユーレ５６を取り付けたものである。The blood circuit 50 shown in FIG. 13 is equipped with a blood pump 52 with an integrated check valve, and the blood circuit 50 shown in FIG.
The one shown in FIG. 15 has a blood removal cannula 56 with a built-in check valve attached.
上記のように、血液回路の途中に逆止弁を設けることに
より、遠心ポンプの停止時に流出口の圧力が流入口の圧
力より高くなっても逆流が生じることを防止でき、また
、特別なりランプ等の操作を行う必要がない。また、遠
心ポンプは通常定常流で使用されており、より生理的に
好ましいと考えられている拍動流を発生するためには、
回転数を２段階で周期的に変化させている。すなわち、
心臓の収縮期に相当する期間には高回転で回転させ、心
臓の拡張期に相当する期間は逆流を防止する程度の低回
転で回転させることによって、液体を周期的に送り出す
ことになる。しかし、逆流防止のために必要な回転数は
、送血部位の血圧、回路の長さ等により相７
違するため、その設定が難しく、また血圧等の変化に応
じ設定を変更することが必要となり、操作がきわめて繁
雑である。しかし、遠心ポンプより下流側に逆止弁を設
けておけばこのような回転数の２段階制御は必要なく、
心臓の拡張期に相当する期間はポンプを完全に停止する
ことができるため、ポンプ制御もより簡略化することが
でき、より効率的に拍動流を得ることができる。As mentioned above, by providing a check valve in the middle of the blood circuit, it is possible to prevent backflow even if the pressure at the outlet becomes higher than the pressure at the inlet when the centrifugal pump is stopped. There is no need to perform operations such as In addition, centrifugal pumps are usually used with steady flow, but in order to generate pulsatile flow, which is considered to be more physiologically preferable, it is necessary to
The rotation speed is changed periodically in two stages. That is,
The liquid is periodically pumped out by rotating at a high rotation speed during a period corresponding to the systolic phase of the heart, and at a low rotation speed enough to prevent backflow during a period corresponding to the diastolic phase of the heart. However, the number of revolutions required to prevent backflow varies depending on the blood pressure at the blood delivery site, the length of the circuit, etc., so it is difficult to set, and it is necessary to change the setting according to changes in blood pressure, etc. Therefore, the operation is extremely complicated. However, if a check valve is installed downstream of the centrifugal pump, this two-step control of the rotation speed is not necessary.
Since the pump can be completely stopped during a period corresponding to the diastolic phase of the heart, pump control can also be simplified and pulsatile flow can be obtained more efficiently.
［発明の効果］
本発明の逆止弁は、中央に拡径部を有する筒状ハウジン
グと、該筒状ハウジングの前記拡径部内に移動可能に収
納された球体とからなる血液回路用逆止弁であって、前
記筒状ハウジングは、第１管状部材と、該第１管状部材
と嵌合する第２管状部材とからなり、そして、前記第１
管状部材と該第２管状部材との接合面はそれぞれ対応し
たテーパー面となっているので、第１管状部材と第２管
状部材を嵌合させ、さらに押圧したとき、両者のテーパ
ー状の接合面におい８
て（さび効果が生じ、通常の平行面接合に比べ、より緊
密に固定され、ハウジングの内面の継目に微小な間隙が
形成されることを抑制し、よって、ハウジングの内面の
継目への血液成分の侵入を防ぎ、血栓の形成を防止する
。[Effects of the Invention] The check valve of the present invention is a check valve for a blood circuit comprising a cylindrical housing having an enlarged diameter portion at the center and a sphere movably housed within the enlarged diameter portion of the cylindrical housing. In the valve, the cylindrical housing includes a first tubular member and a second tubular member that fits into the first tubular member;
The joining surfaces of the tubular member and the second tubular member are respectively tapered surfaces, so when the first tubular member and the second tubular member are fitted and further pressed, the tapered joining surfaces of both 8 (rusting effect occurs, the joints are more tightly fixed than normal parallel surface joints, and the formation of minute gaps at the joints on the inner surface of the housing is suppressed. Prevents the invasion of blood components and prevents the formation of blood clots.
第１図は、本発明の逆止弁の一実施例の断面図、第２図
は、第１図のＡ−Ａ線断面図、第３図は、第１図の逆止
弁における第１管状部材と第２管状部材の接合部分の拡
大断面図、第４図は、第１図に示した逆止弁の第２管状
部材の上面図、第５図は、第４図のＢ−Ｂ線断面図、第
６図は、本発明の逆止弁の他の実施例の断面図、第７図
は、第６図のＣ−Ｃ線断面図、第８図は、本発明の逆止
弁の他の実施例の断面図、第９図は、第８図のＤ−Ｄ線
断面図、第１０図および第１１図は、本発明の逆止弁の
他の実施例の断面図第１２図ないし第１５図は、本発明
の逆止弁を用いた血液回路の具体例を示す図である。
９
１・・・逆止弁、 ２・・・ハウジング、２ａ・・
・第１管状部材、２ｂ・・・第２管状部材、３・・・球
体、 ４・・・液体流入口、５・・・液体流出口
、６・・・突出部、７・・・係止部、 ８・・・拡径
部、８ｃ、８ｄ・・・接合面、 ９・・・接触部０
］
区FIG. 1 is a sectional view of one embodiment of the check valve of the present invention, FIG. 2 is a sectional view taken along line A-A in FIG. FIG. 4 is a top view of the second tubular member of the check valve shown in FIG. 1, and FIG. 6 is a sectional view of another embodiment of the check valve of the present invention, FIG. 7 is a sectional view taken along the line CC of FIG. 6, and FIG. 8 is a sectional view of another embodiment of the check valve of the present invention. FIG. 9 is a sectional view taken along the line DD in FIG. 8, and FIGS. 10 and 11 are sectional views of other embodiments of the check valve of the present invention. 12 to 15 are diagrams showing specific examples of blood circuits using the check valve of the present invention. 9 1...Check valve, 2...Housing, 2a...
・First tubular member, 2b... Second tubular member, 3... Sphere, 4... Liquid inlet, 5... Liquid outlet, 6... Projection, 7... Locking Part, 8... Expanded diameter part, 8c, 8d... Joint surface, 9... Contact part 0 ] Ward
Claims (3)
ハウジングの前記拡径部内に移動可能に収納された球体
とからなる血液回路用逆止弁であって、前記筒状ハウジ
ングは、第１管状部材と、該第１管状部材と嵌合する第
２管状部材とからなり、そして、前記第１管状部材と該
第２管状部材との接合面はそれぞれ対応したテーパー面
となっていることを特徴とする血液回路用逆止弁。(1) A check valve for a blood circuit comprising a cylindrical housing having an enlarged diameter part in the center and a sphere movably housed in the enlarged diameter part of the cylindrical housing, wherein the cylindrical housing is , consisting of a first tubular member and a second tubular member that fits into the first tubular member, and the joint surfaces of the first tubular member and the second tubular member are respectively tapered surfaces. A check valve for blood circuits characterized by:
環状部材を有し、前記第１管状部材もしくは第２管状部
材のいずれか一方には、前記環状部材が有する第１のネ
ジ部と螺合する第２のネジ部を有し、該第１のネジ部と
第２のネジ部とが螺合することにより、前記第１管状部
材と第２管状部材との接合面を押圧可としている請求項
１に記載の血液回路用逆止弁。(2) The blood circuit check valve has an annular member having a first threaded portion, and either the first tubular member or the second tubular member has a first threaded portion that the annular member has. has a second threaded part that is threadedly engaged with the threaded part of the first threaded part, and the first threaded part and the second threaded part are threadedly engaged, thereby forming a joint surface between the first tubular member and the second tubular member. 2. The blood circuit check valve according to claim 1, wherein the check valve is pressable.
れか一方は、嵌合部に突起を有し、前記第１管状部材ま
たは前記第２管状部材の他方は、前記突起に対応した凹
部有している請求項１または２に記載の血液回路用逆止
弁。(3) Either the first tubular member or the second tubular member has a protrusion in the fitting portion, and the other of the first tubular member or the second tubular member has a recess corresponding to the protrusion. The blood circuit check valve according to claim 1 or 2, comprising:
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007297A JPH03212269A (en) | 1990-01-16 | 1990-01-16 | Check valve for blood circuit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007297A JPH03212269A (en) | 1990-01-16 | 1990-01-16 | Check valve for blood circuit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH03212269A true JPH03212269A (en) | 1991-09-17 |
Family
ID=11662090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007297A Pending JPH03212269A (en) | 1990-01-16 | 1990-01-16 | Check valve for blood circuit |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH03212269A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009150893A1 (en) * | 2008-06-11 | 2009-12-17 | 株式会社サンメディカル技術研究所 | Artificial heart control device, artificial heart system, and artificial heart control method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6212086B2 (en) * | 1977-04-29 | 1987-03-17 | Bosch Gmbh Robert | |
| JPS62159867A (en) * | 1985-12-31 | 1987-07-15 | Nippon Zeon Co Ltd | Valve device |
-
1990
- 1990-01-16 JP JP2007297A patent/JPH03212269A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6212086B2 (en) * | 1977-04-29 | 1987-03-17 | Bosch Gmbh Robert | |
| JPS62159867A (en) * | 1985-12-31 | 1987-07-15 | Nippon Zeon Co Ltd | Valve device |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009150893A1 (en) * | 2008-06-11 | 2009-12-17 | 株式会社サンメディカル技術研究所 | Artificial heart control device, artificial heart system, and artificial heart control method |
| US9125977B2 (en) | 2008-06-11 | 2015-09-08 | Sun Medical Technology Research Corporation | Artificial heart control device, artificial heart system and artificial heart control method |
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