JPH03118302A - Antimicrobial and mildewproofing powder alcohol composition - Google Patents

Abstract

PURPOSE:To obtain the title readily handleable composition extremely useful in terms of industry, having excellent germicidal effects by adsorbing a specific anhydrous lower alcohol on a polyvinyl alcohol-based resin adsorbent having specific degree of saponification in a specific ratio. CONSTITUTION:70-200 pts.wt. 1-3C anhydrous lower alcohol such as methanol, ethanol or 1-propanol having germicidal effects is blended with 100 pts.wt. polyvinyl alcohol (PVA for short)based resin having 60-90mol% degree of saponi fication as an adsorbent at room temperature while stirring and adsorbed on the resin to give the objective composition having high germicidal power per unit volume by simple procedure. The PVA-based resin used generally has <=840mu average particle diameter and 400-3,000 average degree of polymerization and not only a saponified polyvinyl acetate but also a saponified vinyl acetate copolymer copolymerized with a small amount of a component except vinyl acetate may be used as the resin. The composition is used especially for an antimicrobial and mildewproofing agent for foods.

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial Field of Application] The present invention relates to an easy-to-handle antibacterial and antifungal powder alcohol composition that utilizes the bactericidal action of lower alcohols.

[Prior art] The bactericidal properties of lower alcohols have been well known,
It is used as alcohol vapor for antibacterial and antifungal purposes in foods, feed, etc. However, if the source of alcohol vapor remains in liquid form, even if the alcohol is placed in a bag-like container or the like and placed in the system, there is a risk of direct contact with the contents due to liquid leakage due to vibrations, shocks, etc. always exists.

Therefore, in Japanese Patent Publication No. 55-2273, starch, sugar,
Powdered ethanol in which ethanol is adsorbed on a carrier such as dextrin, cellulose-free, methyl cellulose, ethyl cellulose, gelatin, silicon dioxide, aluminum silicate, talc, etc. is used, and in JP-A No. 63-63777, ethanol and sugar alcohol are used. Powdered ethanol obtained by heating and melting a mixture of ethanol and cooling and pulverizing the mixture is used to prevent liquid leakage. Also, JP-A-58-56669
The publication discloses a manufacturing method in which a carrier is added to an alcohol-containing liquid, and after swelling and dissolution, the solution is sprayed and freeze-dried to obtain a powdered liquor.

[Problems to be Solved by the Invention] However, the powdered ethanol disclosed in Japanese Patent Publication No. 55-2273 uses silicon dioxide, aluminum silicate,
When using something with a low apparent specific gravity, such as talc, the product becomes bulky, making transportation and storage inconvenient, and the sterilizing power of powdered ethanol tends to be low on a unit volume basis. On the other hand, in the case of starch, sugar, dextrin, cellulose, gelatin, etc., which have a higher apparent specific gravity than such carriers, this problem does not occur, but the porosity is low, so the adsorption capacity for ethanol itself is inferior, and this is also a practical problem. It is not sufficient in terms of its sterilizing power. Furthermore, the method of JP-A No. 63-63777 involves heating melting, cooling pulverization, etc.
The method described in Japanese Patent No. 56669 requires the use of special means such as spray freeze-drying, which increases the number of manufacturing steps and requires new equipment, which is a disadvantage. As described above, the reality is that it is still not possible to obtain powdered alcohol with high bactericidal power using a simple production method using any of the conventional methods.

[Means for Solving the Problems] Therefore, the present inventors continued intensive research on carriers that adsorb alcohol, and found that when using polyvinyl alcohol (hereinafter abbreviated as PVA)-based resin,
The inventors have discovered that such objects can be achieved and have completed the present invention.

That is, the present invention provides: U PVA-based fruit tree with a degree of saponification of 60 to 90 mol% +
70 to 70 parts by weight of anhydrous alcohol having 1 to 3 carbon atoms
An antibacterial and antifungal powder alcohol composition containing 200 parts by weight. It is Go.

A feature of the present invention is that an anhydrous lower alcohol is adsorbed onto a PVA resin having a specific degree of saponification. As a result, an antibacterial and antifungal powder alcohol composition with a sufficient amount of alcohol adsorption and high bactericidal power per unit volume can be obtained with a simple operation.

The PVA-based resin of the present invention may be not only a saponified product of polyvinyl acetate, but also a saponified product of a copolymer obtained by copolymerizing a small amount of components other than vinyl acetate.

Components other than vinyl acetate, such as ethylene, propylene, isobutylene, α-octene, α-dodecene, α
Olefins such as octadecene, unsaturated acids such as acrylic acid, methacrylic acid, crotonic acid, maleic acid, maleic anhydride, itaconic acid, or their salts or mono- or dialkyl esters, nitriles such as acrylonitrile, methacrylonitrile, etc. Amides such as acrylamide and methacrylamide, olefin sulfonic acids or their salts such as ethylene sulfonic acid, allyl sulfonic acid and methalylsulfonic acid, alkyl vinyl ethers, N-acrylamidomethyl trimedelammonium chloride, allyl trimedel ammonium chloride , dimethyl diallyl vinyl ketone, N-vinylpyrrolidone, vinyl chloride, vinylidene chloride, and the like.

It is also possible to use PVA that has been modified by acetalization, glyoxalization, acetoacetylation, esterification, sulfonation, cationization, etc.

The degree of saponification of the PVA resin of the present invention is 60 to 90 mol%, preferably 60 to 80 mol%. If the amount is less than 60 mol %, the PVA resin will become gel-like due to the absolute alcohol, and if the degree of saponification is further reduced, it will dissolve and will no longer be in the form of powder. If it exceeds 90 mol%, absolute alcohol becomes difficult to adsorb to the PVA-based resin, the bactericidal power decreases, and it is not practical.

PVA resin has an average particle size of 840μ or less for boat fishing;
Preferably, those having a polymerization degree of 500 or less are used, and the average degree of polymerization is also selected from 400 to 3,000, preferably 500 to 2,000, but there is no particular restriction.

As the anhydrous alcohol of the present invention, alcohols having 1 to 3 carbon atoms can be used, such as methanol, ethanol, 1-propatol, 2-propatol, and the like. If such alcohol contains water, the water will reduce the PV
Since the A-based resin is welded or dissolved, drying and pulverization steps are required to obtain powdered alcohol, which is disadvantageous because the alcohol evaporates together with water during drying, which naturally deteriorates the properties of powdered alcohol.

The blending ratio of the PVA resin and absolute alcohol of the present invention is as follows:
5 to 5 parts of absolute alcohol per 100 parts by weight of PVA resin
The amount is 200 parts by weight, preferably 50 to 150 parts by weight.

If it is less than 5 parts by weight, the amount of alcohol contained is too small and the bactericidal ability is too low to be practical. If the amount exceeds 200 parts by weight, the liquid alcohol will coexist with the powdered alcohol, and solid-liquid separation will occur, making powderization impossible.

As a method for producing the powdered alcohol composition of the present invention, it is sufficient to simply add a predetermined amount of absolute alcohol to the above-mentioned PvA resin and stir and mix at room temperature. In addition, PVA fruit tree 1
1i Add a predetermined amount or more of anhydrous alcohol, stir and mix, then separate the powdered alcohol, and if necessary dry it to obtain a powdered alcohol with a predetermined composition, especially if the composition can be changed. There are no restrictions.

Furthermore, other known additives such as other known bactericides and pigments may be added to the powdered alcohol composition at the time of manufacture, or the powders may be mixed together.

The composition of the present invention mainly includes raw foods such as bread, meat, and fish;
It is particularly useful as an antibacterial and fungicidal agent for foods such as dried foods, grains, vegetables, and fruits, but is not limited to such uses.

In use, the target substance may be hermetically sealed in any bag or container, and the composition of the present application may be placed in the bag or container.

When using the composition of the present invention, the composition may be placed directly in an unpackaged state, or placed in a container such as an open container or a bag made of an alcohol-permeable resin film. You may do so, and there are no particular restrictions. - Examples of alcohol-permeable resins used in boat fishing include polyethylene, polypropylene, ethylene-vinyl acetate copolymer PVA, and the like.

[Function] The antibacterial and antifungal powder alcohol composition of the present invention can be obtained by a simple operation, and the PVA resin with a specific saponification degree range used as an adsorption carrier in the present invention has a specific degree of polymerization. Regardless, it has the effect of adsorbing a sufficient amount of alcohol for sterilization.

[Example] Next, the present invention will be explained in detail with reference to Examples.

(i) Production of powder alcohol Production example I PVA powder 202 with a degree of polymerization of 500 and a degree of saponification of 70 mol%
Absolute ethanol 201j was added to the mixture, and the mixture was stirred at room temperature for 30 minutes to obtain powdered alcohol (A). Apparent specific gravity is 0.8
7, and 100 parts by weight of absolute ethanol was supported on 100 parts by weight of PVA powder.

Production Examples 2 to 9 Powder alcohols (B) to (E) were prepared in the same manner as on the same side except that the carrier shown in Table 1 and absolute alcohol were used instead of the PVA powder and absolute ethanol in Production Example 1.
, (a) to (d) were obtained, and the apparent specific gravity and the amount of anhydrous alcohol supported are also shown in Table 1.

(11) Powdered alcohol performance test Example 1 (see Figures 1 and 2) Sterilized potato dextrose agar medium (20% by weight of Bareischif infusion, 2% by weight of glucose, 1.5% by weight of agar, pH 5, 0) ) Nyare I with a diameter of 9cm
was placed in the center of a paper box 2 with a width of 25 cm, a depth of 34 cm, and a height of 8 cm (interior laminated with polyethylene) without a top lid 3, and a spore suspension of the following five types of mold was placed on the agar medium surface. Inoculated by spraying.

Aspergillus sniker (IFo 6341) Venisorus funiculosum (IFo 6345) Rhizopus stolonifer (IFO3]005) Cladosporium cladosporioides (IPO634,8
) Chaetomium dalobosum (IFO6347) Thickness 3
1.15 cm3 (1) 7) of powdered alcohol (
After fixing both ends of the powdered alcohol preparation containing A) 4 to the center of the inside of the upper M3 with adhesive tape 6, the upper lid 3 was covered and the paper box was stored at room temperature.

Seven doses of M3 were taken orally and the extent of mold growing on the agar medium was observed.

Control Example I An experiment was conducted in the same manner as in Example 1 except that the powdered alcohol preparation was not used, and the results are shown in Table 2.

Examples 2 to 5, Control Examples 2 to 4 Instead of powder alcohol (A) in Example 1, powder alcohols (B) to (E), (b) to (d) shown in Table 1 were used.
An experiment was conducted in the same manner as in the same example except that .

0 Since the alcohols shown in Table 1 are in gel form and have a different purpose from the powdered alcohols of the present invention, a mold growth test was not conducted.

**Mold growth condition -: No growth, + 1 Mold grows on the 115 area of the top surface of the Noyale medium; Mold grows on the 215 area of the top surface of the Noyale medium ÷ 315 of the top surface of the Noyale medium Mold grows on an area of 415 on the surface of the second part of "Noyale's medium" Part 7: Mold grows on the entire surface of the second part = 11 [Effect] Prevention of the present invention The PVA-based resin with a specific saponification degree range used as an adsorption carrier in the powdered alcohol composition for anti-bacterial fungi has the ability to adsorb a sufficient amount of alcohol per unit volume, regardless of its degree of polymerization. The resulting composition of the present invention has a high bactericidal power per unit volume, and the method for producing the composition is simple, making it an extremely useful invention industrially.

[Brief explanation of drawings]

The drawing shows a paper box (the interior is laminated with polyethylene) used in the performance test of the antibacterial and antifungal powder alcohol of the present invention, and shows a Petri dish containing an agar medium and a seven powdered alcohol preparation placed inside. FIG. 1 is a longitudinal sectional view of such a box, and FIG. 2 is a diagram showing the arrangement of the powdered alcohol preparation inside the upper box. l; Agar medium 2, paper box (main body) (interior polyethylene laminate) 3;
Paper box top lid (interior polyethylene laminate) 4; Powdered alcohol 5 PVA film bag: Adhesive tape

Claims (1)

[Claims] 70 parts by weight of anhydrous alcohol having 1 to 3 carbon atoms to 100 parts by weight of polyvinyl alcohol resin with a degree of saponification of 60 to 90 mol%.
An antibacterial and antifungal powder alcohol composition containing ~200 parts by weight.