JPH02307480A - Intravenous atrial septal defect hole closing apparatus - Google Patents

Abstract

PURPOSE:To close the defect part of a septum interatriale without performing the incision of the thorax and the heart by connecting the dilated part on the side of the left atrium and the dilated part on the side of the right atrium by a defect hole closing means through the septum interatriale part capable of piercing a defect hole. CONSTITUTION:The small vein of the cervix is exposed to be incised and a connection tube 4 unified with balloons 1, 2, 3 folded small is inserted in the small vein and passed through the atrial septal defect hole 23 to be inserted in the left atrium 20. For example, a physiologlcal saline solution is injected in a fine tube 5 from the terminal end part thereof on the atmosphere side to inflate the balloon 1 to close the fine tube 5. The balloon 1 is brought into close contact with a septum interatriale 19 and the physiological saline solution is injected in a fine tube 6 to inflate the balloon 2 to close the fine tube 6. The connection pipe 4 is pulled and the physiological saline solution is injected from a fine tube 7 to inflate the balloon 3 in the right atrium 18 to close the fine tube 7. The atrial septal defect hole 23 is closed in a state grasped in an H-shape by the balloon 1 on the side of the left atrium 20, the balloon 2 at the part of the atrial septal defect hole 23 and the balloon 3 on the side of the right atrtum 18 and the fundamental abnormality of an atrial septal defect such that blood flows backward from the left atrium 20 to the right atrium 18 is almost corrected.

Description

[Detailed Description of the Invention] [Industrial Application Field] The present invention is a method for repairing atrial septal defects, which are frequently seen as a congenital heart disease, through veins without performing surgery. The present invention relates to a transvenous atrial septal defect closure device that aims at treatment by inserting and indwelling a closing structure.

[Prior art 1] Atrial septal defect is a congenital defect in the atrial septum, which is the dividing wall between the right atrium and the left atrium. functional decline and pulmonary hypertension,
It is a disease that causes lung infections. It is the most common congenital heart disease, and is generally irreversible unless the defect is surgically closed during elementary or junior high school age.
Because it causes damage to the pulmonary system, it is an important target for cardiac surgery. Conventionally, in order to surgically close this defect, the thorax and heart were incised, and the defect hole was sewn together using a heart-lung machine or a special patch was sewn on.

[Problems to be Solved by the Invention] As described above, even with the above-mentioned conventional techniques and techniques, it is possible to treat atrial septal defect through surgery, and this surgery has also improved due to recent medical advances. It's pretty safe.

However, this surgery requires advanced techniques and equipment similar to what is called cardiac surgery, and it also causes major surgical invasion of the living body, causing anxiety for the patient and his family, and the psychological impact of scars remaining on the chest after the surgery. It had problems that cannot be ignored.

The present invention solves these problems and closes a defect in the atrial septum using a defect closure structure inserted through a small incision in a peripheral vein such as a jugular vein without making an incision in the thorax or heart. The purpose of the present invention is to provide treatment using simple means and to eliminate most of the problems in the conventional techniques mentioned above.

[Means for Solving the Problem 1] A means for solving the above object is, as described in the claims, a defect in the atrial septum that is attached to the tip of a tubular means inserted through an incision in a vein such as the neck. A transvenous atrial septum, which is a hole closing means and has a structure in which the enlarged part located on the left atrium side and the enlarged part located on the right atrium side are connected via an atrial septal part that can pass through the defect hole. It is a defect hole closure device.

The device is inserted by tubular means via a vein into the defect in the atrial septum and placed to close the defect and prevent backflow of blood from the left atrium to the right atrium.

Hereinafter, the effects and the like of the present invention will be explained based on Examples.

[Example 1 (Description of drawings related to the embodiment) Figures 1 to 29 are diagrams showing five embodiments based on the present invention.

First, FIGS. 1 to 12 show a first embodiment, and are diagrams showing the structure and insertion procedure when the defect hole closing structure is a structure in which three independent balloons are integrally joined. Fig. 1 is an assembled external view of the entire device, Fig. 2 is an external view of the balloon in a deflated state, Fig. 3 is an enlarged view of the external end of the connecting tube,
Figure 4 is a parent view showing the outside of the closed laurel at the end of the capillary inside the connecting tube, Figure 5 is an external view of the cap for closing the outer end of the connecting tube, and Figure 6 is a perspective view showing the state of connection between each balloon part and the capillary. Figure, 7th~
FIG. 12 is a diagram showing the operational process from insertion of the balloon through the incision to completion of closure of the atrial septal defect.

13 to 15 show a second embodiment, in which the defect hole closing structure is a balloon-like structure in which the defect hole closing structure is integrally connected and the inside thereof is communicated, and the left atrium, the atrial septum, and the right atrium. FIG. 7 is a diagram showing a gradual change in shape of each balloon during closure of an atrial septal defect when each balloon has a different elongation rate with respect to pressure.

16 to 22 show a third embodiment, in which the defect hole closing structure is formed by integrally forming a membranous left atrium insertion part and a balloon-shaped atrial septal insertion part, and further forming them independently. FIG. 3 is a diagram showing the structure and insertion procedure of a structure in which a membrane-like right atrium insertion portion is connected with a magnet. Fig. 16 is an external view of the membranous left atrium insertion part and the balloon-like atrial septal insertion part attached to the tip of the injection tubule, as well as an external view of the membranous right atrium insertion part; Figures 1 to 21 are diagrams showing the operational process from insertion to completion of atrial septal defect closure. 22nd
The figure is a partial side sectional view when the defect hole closing structure has been inserted in this embodiment.

23 to 28 show a fourth embodiment, which consists of a membranous left atrium insertion part and a right atrium insertion part in which the defect hole closing structure is formed independently, and each membranous insertion part FIG. 3 is a diagram showing the structure and insertion procedure in the case where the structure is connected by a magnet.

FIG. 23 is an external view of a membranous left atrium insertion part and a membranous right atrium insertion part attached to the tip of the injection thin tube.

Moreover, FIGS. 24 to 27 are diagrams showing the operational process from insertion to completion of closure of the atrial septal defect hole, and FIG. 28 is a partial side sectional view at the time of completion of attachment of the defect hole closure structure in this embodiment.

FIG. 29 is a diagram showing a fifth embodiment, in which only the defect hole closing structure is placed in the defect hole portion, and the connecting tube for operating the structure is removed.

In Figures 1 to 29, 1 is the balloon inserted into the left atrium, 2 is the balloon inserted into the atrial septum, 3 is the balloon inserted into the right atrium, and 4 is the balloon inserted through the incision. Communication tubes connecting the defect hole closing structure and the outside; 5.6.7 are thin tubes installed inside the communication tubes and open into the inside of the balloon 1.2.3; 8.9.10 are thin tubes 5, respectively. .6.7,
Inflatable material that injects liquid or gas into the balloon through the balloon 1.2.3 to inflate it, or expel it to deflate it.
``Injection/evacuation device, 11 is a cap for closing the capillary end, 12 is a cap for closing the connecting tube, 13 is a jugular vein, 14 is a skin incision line,
15 is the superficial jugular venous incision, 16 is the superior vena cava, 17 is the superior vena cava, 18 is the right atrium, 19 is the atrial septum, 20 is the left atrium, 2
1 is the right ventricle, 22 is the left ventricle, 23 is the atrial septal defect, 2
4 is a hollow catheter; 25 is a membrane inserted into the left atrium;
26 is a membrane inserted into the right atrium, 27.28 is a magnet, 2
9 is a fixed thread, 30.31.32 is a needle that communicates the thin tube 5.6.7 with the balloon 1.2.3 and the inside, 33.34
．． 35 is a partition made of a soft and flexible material.

(First example) First, a first embodiment will be described based on FIGS. 1 to 12.

In this example, balloons 1 and 2.3 are inserted through the superficial jugular venous incision 15, through the superior vena cava 16 and the right atrium 18, into the atrial septal defect hole 23, and then into the left atrium 20. Inflatable material injector/discharge device 8 from the connected thin tube 5.6.7
．． 9.10, blood is transferred from the left atrium 20 to the right atrium 18 by injecting liquid, gas, or resin depending on the conditions, and placing the inflated balloon 1.2.3 in the atrial septal defect hole. It prevents the reflux of blood and treats hemodynamic abnormalities associated with atrial septal defect.

Each balloon is sufficiently thin and flexible so as not to damage the inner wall of each organ when inserted into a blood vessel or the heart, attached or removed, or left in the heart for a long period of time, and is also sufficiently flexible to prevent the formation of blood clots. The balloon 1 is made of, for example, Tear-on, Dacron, Votex, silicone rubber, etc., and is placed in the left atrium 20, and the balloon is placed in the atrial septal defect hole 23. 2. It consists of three independent parts of the balloon 3 which are located in the right atrium I8. Each balloon 1.2.3
5.6.7 Capillary tubes each opening independently in ,
is located in communication with the atmosphere. 3 thin tubes 5.6
．． 7 is bundled into one bundle and is sufficiently flexible so as not to damage the inner walls of each organ when inserted, withdrawn, or placed in a blood vessel or heart, as well as a balloon, and does not form a blood clot. For example, it is inserted into a communication pipe 4 made of a silicon-coated tube or the like. Each balloon and the communication tube 4 are integrally formed and smoothly formed, and each material is mixed with an X-ray opaque substance in advance so that insertion and attachment into the heart can be performed completely by X-ray observation. .

As shown in FIGS. 3 to 5, the open ends of the thin tubes 5, 6.7 inserted into the communication tube 4 on the outside air side are provided with thin tubes to prevent the expansion material from flowing backward after injection. It has a structure in which an end closing laurel 11 and a connecting pipe closing cap 12 for preventing the plug 11 from escaping are housed.

Next, the procedure from insertion of the defect hole closing structure to attachment at a predetermined position in this example will be explained.

■ First, as shown in Fig. 7, a small incision is made on the neck skin to expose and incise the cervical venule (superficial jugular vein), followed by a small balloon 1.2.3 and a connecting tube 4 integrated with it. Insert while pushing forward grammatically.

■Each balloon part and the communicating tube 4 integrated with it can be easily connected from the superior vena cava 16 to the right atrium 1 as shown in Figs.
8. Furthermore, it can be inserted into the left atrium 20 through the atrial septal defect hole 23, but all operations including that operation described below are performed under observation using X-ray fluoroscopy or cardiac ultrasound.

■Next, as shown in FIG. 10, for example, physiological saline is injected from the atmospheric side end of the thin tube 5 using the inflation material injector/discharge device 8, and the balloon I is first inflated in the left atrium 20, and then the thin tube ends. A laurel 11 is inserted to close the thin tube 5.

■Next, as shown in FIG. 11, while gently pulling the entire connecting tube 4 and bringing the balloon 1 into close contact with the atrial septum 19, saline is similarly injected into the atmospheric side end of the thin tube 6, and the balloon 2 Inflate the capillary 6 by closing the capillary end laurel 11
will be closed.

Next, as shown in Fig. 12, while being careful not to loosen the tension on the connecting tube 4, physiological saline is similarly injected through the tubule 7 to inflate the balloon 3 in the right atrium 18 and close the end of the tubule. Close the tubule 7 with laurel 11. As a result, the atrial septal defect hole 23 is connected to the balloon 1 on the left atrium 20 side,
The basic idea of an atrial septal defect is that the balloon 2 at the atrial septal defect hole 23 and the balloon 3 at the right atrium 18 are sandwiched in an H shape and closed, and blood backflows from the left atrium 2° to the right atrium 18. Most of the abnormalities will be corrected.

■Finally, a cap 12 for closing the connecting pipe 4 is placed at the end of the connecting pipe 4.
This completely prevents leakage of the physiological saline used as the inflation material injected into the balloon. The communication tube 4 is sufficiently fixed to the inserted vein with surgical thread, the excess end is buried subcutaneously, and the skin incision is sutured to complete the entire operation.

In addition, if you want to replace the balloon with a larger balloon as the patient grows, or if it becomes necessary to replace the balloon due to breakage of the balloon for some reason, we will first insert the balloon instead of inserting the balloon. 39
Next, balloon 2. Then, the balloons 1 can be easily removed and replaced by extracting the injected inflation material from the balloons 1 using the inflation material injection/discharge device 10.9.8 and deflating each balloon.

In addition, even if the balloon breaks for some reason, the inflation material inside the balloon is physiological saline if it is a liquid, or carbon dioxide if it is a gas, so there is no danger to the human body due to leakage. Never.

(Second Embodiment) Figures 13 to 15 show a second embodiment, in which the balloon for closing the atrial septal defect hole 23 in the embodiment @1 is connected to the 20th part of the left atrium and the 19th part of the atrial septum. Whereas the 18 parts of the right atrium each formed an independent chamber through a septum,
The balloon for closing the atrial septal defect hole 23 in this embodiment is integrally formed with the left atrium 20, the atrial septum 19, and the right atrium 18 communicating internally, and each balloon has a different pressure response. The structure maintains the same elongation rate. That is, by changing the material or thickness of each balloon, the elongation rate in response to pressure can be changed, for example, the left atrium 2
Part 0 is l OOmm [(,0, part 19 of the atrial septum is 200
The right atrium 18 is maintained at a predetermined shape and size by a pressure of 300 mmH, o.

When inserting it into the atrial septal defect hole 23, first open the superficial jugular venous incision 1 in the same manner as in the first embodiment.
Insert each balloon part and the connecting tube 4 integrated with it from 5 and push it forward. After confirming that the balloon At has reached the left atrium 20, a liquid or gaseous substance is inserted from the thin tube 5 inserted into the connecting tube 4. Inject the inflatable material. balloon l,
Since the insides of the balloons B2 and 3 are communicated with each other, each balloon is filled with the injected inflation material. When the inflation material is further injected and the pressure is increased to l Q Q mmH,o, the balloon 1 in the left atrium 20 first inflates and maintains a predetermined shape, as shown in FIG. 813. Next, the connecting tube 4 is pulled to bring the balloon 1 into close contact with the atrial septum 19, and the injection of the inflation material is continued to increase the pressure to 200 mmJo. Accordingly, the balloon 2 is inflated to a predetermined size as shown in FIG. 14, and the atrial septal defect hole 23 is closed. Furthermore, when the pressure of the injected expansion material is increased to 300 mmH, O while being careful not to loosen the tension on the connecting tube 4, the balloon 3 inflates in the right atrium 18 as shown in FIG. 15 and reaches a predetermined shape. . Then, as in the first embodiment, the ends of the thin tube 5 and the communicating tube 4 are closed, and after the ends are sufficiently fixed to the incised vein with surgical thread, the skin incision is sutured. As a result, the atrial septal defect hole 23 is closed by being sandwiched in an H shape by the balloon 1 on the left atrium 20 side, the balloon 2 in the atrial septal defect hole 23, and the balloon 3 on the right atrium 18 side. Backflow of blood into the right atrium 18 is corrected.

(Third Example) Next, a third example will be described based on FIGS. 16 to 22. In this embodiment, the defect hole closing means includes a membrane 25 inserted into the left atrium 20 and a balloon inserted into the atrial septum 19 and integrally formed with the membrane 25, as shown in FIG. 2, a thin tube 6 connected thereto, and an independently formed membrane 26 inserted into the right atrium 18. The procedure for inserting the defect hole closing structure into the atrial septal defect hole 23 based on this example will be described below.

First, as shown in FIG. 17, a thin tube 6 with a membrane 25 for the left atrium 20 made of a thin tear tube or the like and a balloon 2 for the atrial septum 19 formed integrally with the membrane 25 attached to the tip.
is passed through the hollow catheter 24. The hollow catheter 24 is made of a silicone-coated tube or the like, and by pushing the hollow catheter 24 through the incision 15, the membrane 25 at the tip and the balloon 2 pass through the blood vessel and first enter the right atrium 18, causing an atrial septal defect. It passes through hole 23 and enters left atrium 20 . The balloon 25 is folded toward the balloon 2 side when passing through a narrow part such as a blood vessel, but while it is indwelled in the left atrium 20, it unfolds into a flat plate shape as shown in FIG. Next, as shown in FIG. 19, the thin tube 6 and the hollow catheter 24 are pulled lightly, and the inflation material is injected into the balloon 2 through the thin tube 6 with the membrane 25 in contact with the atrial septum 19. With this, balloon 2 is carved,
The atrial septal defect hole 23 is in a closed state.

Next, while maintaining this state by pulling the thin tube 6, only the hollow catheter 24 is removed, and the membrane 2 is removed as shown in FIG.
A membrane 26 made of the same material as 5 is passed through a small hole drilled between two magnets housed in the center of the membrane C26, and the thin tube 6 is again placed so as to be covered with the hollow catheter 24. , the membrane C26 is inserted up to the atrial septal defect hole 23 by pushing the hollow catheter 24 toward the atrial septal defect hole 23. The membrane 26 inserted into the right atrium 18 naturally unfolds into a flat plate while indwelling within the heart. Right atrium 1 of balloon 2
A magnet 27 is housed near the center of the end on the 8th side, and a magnet 28 is housed near the center of the left atrium 20 side of the membrane 26 . As a result, as shown in FIG. 21, the balloon 2 integrated with the membrane 25 and the membrane 26 are firmly attached by magnetic force, and the second
As shown in FIG. 2, the atrial septal defect hole 23 is closed. Thereafter, the hollow catheter 24 is removed and the thin tube 6 is closed in the same manner as in the first and second embodiments. Then, the end of the tubule b6 is fixed to the incised vein with surgical thread, and the skin incision is sutured to complete the entire operation. Membrane 25, and balloon 2 and membrane 26
As the coupling means, mechanical coupling means other than magnets can be used.

(Fourth Example) A fourth example will be described based on FIGS. 23 to 28. The defect hole closing means in this embodiment is formed by a membrane 25 inserted into the left atrium 20, a membrane 268 inserted into the right atrium 18, and a connecting means for connecting these, as shown in FIG. ing.

Both the membrane 25 and the membrane 26 are made of thin Teflon or the like, and the atrial septum 19 is approximately located in the center of the membrane 25.
A magnet 27 with a height equal to the wall thickness is installed, and a fixed thread 29 is fixedly installed in the center of the magnet 27. membrane 2
A magnet 28 is also attached to the center of the magnet 6, and a small hole through which a fixed thread 29 can pass is bored in the center. The procedure for inserting into the atrial septal defect hole 23 is to first insert the hollow catheter 24 made of a silicone-coated tube or the like so that the fixing thread 29 fixed to the membrane 25 is passed through the catheter. The membrane 25 is folded to the side of the fixing thread 29, inserted through the superficial jugular venous incision 15, and pushed forward with the hollow catheter 24, as in the case of the third embodiment. Accordingly, the membrane 25 passes through the blood vessel and first enters the right atrium 18 as shown in FIG. 24, then passes through the atrial septal defect hole 23 and enters the left atrium 20. @25, which was folded during insertion, is the left atrium 20
While indwelling in the tube, it expands into a flat plate as shown in Figure 25. In this state, the fixing thread 29 and the hollow catheter 24 are pulled lightly, and the hollow catheter 24 is removed from the fixing thread 29 with the membrane 25 in contact with the atrial septum 19. Next, the fixing thread 29 is passed through a small hole made in the center of the membrane 26, and the hollow catheter 24 is attached to cover the fixing thread 29, and the hollow catheter 24 is inserted into the atrial septal defect hole 23.
Insert the membrane 26 to the atrial septal defect hole 23 by pushing it to the side. The membrane 26 inserted into the right atrium 18 naturally unfolds into a flat plate while indwelling within the heart.

A magnet 27 is installed near the center of the end of the membrane 25 on the right atrium 18 side, and a magnet 28 is installed near the center of the apex 26 on the left atrium 20 side. 25
The membrane 26 is firmly attached to the membrane 26 by magnetic force, and the atrial septal defect hole 23 is closed as shown in FIG. Thereafter, the hollow catheter 24 is removed, the end of the fixing thread 29 near the incision is connected to the incised vein, and the skin incision is sutured to complete the entire operation. Mechanical coupling means other than magnets can also be used as coupling means for the membranes 25,26.

(Fifth Example) In the atrial septal defect closing devices described in the first to fourth examples above, the connecting tube used for inserting the defect closing means into the atrial septal defect hole is 4. The thin tube 6 or the fixing thread 29 is tightly attached inside the body near the superficial jugular venous incision 15.

On the other hand, the fifth embodiment shown in FIG. 29 is an example in which only the defect hole closing means is left in the heart, and the means for attaching it is removed from the body. In the example in this figure, the first
As in the embodiment shown in FIG.
A similar partition wall 34 is provided between the balloon 3 and the balloon 3.
A similar partition wall portion 35 is provided between the connecting pipe 4 and the connecting pipe 4 . Between each balloon and the capillary 5.6.7,
A needle 30.31.32 is provided through the septum 33.34.35. The procedure for attaching this to the defect hole is the first step.
This embodiment is similar to that of the embodiment, but in this embodiment, when the capillary tube 5.6.7 is removed after installation, the needle 30.31.
32 is removed through the partition part 33, 34, 35,
Since the partition wall is made of a flexible and visible material, the extraction hole is closed and the fluid inside is prevented from leaking out. Thereafter, by further removing and withdrawing the communicating tube 4 from the septum 35, only the atrial septal defect closing device consisting of the balloon 1.2.3 can be left in the heart.

Further, for example, when the defect hole closing structure is composed of a balloon structure with an internally connected structure as in the second embodiment,
A reversal valve made of the same material as the connecting tube 4 is installed on the superior vena cava side of the balloon in the right atrium 18, and a removable fitting part is provided at the connection between the connecting tube 4 and the balloon. At the time of insertion, the balloon is inflated by injecting an inflation material from the connecting tube 4 through the check valve, and after the insertion is completed, the connecting tube 4 is removed from the removable fitting part and pulled out of the body, thereby creating the defect hole closing structure. It is also possible to indwell only the heart.

If it becomes necessary to replace the defect hole closing structure in the future due to growth of the patient, etc., the connecting tube 4 is inserted again and connected to the defect hole closing structure using the removable fitting part, and then The check valve is pushed open by a thin tube inserted into the communication tube 4, and the expansion material is discharged from the body through the communication tube 4. The contracted defect hole closing structure is easily taken out of the body through the vein, and a new defect hole is closed. It is also possible to replace the structure.

[Effects of the Invention] As explained in the above embodiments, the present invention is applicable to the treatment of atrial septal defect, which is the most frequently observed congenital heart disease, by eliminating the conventional incision into the thorax and heart. In contrast to the method of suturing the defect hole or sewing together a special patch using a heart-lung machine, a balloon-like or thin membrane-like material that can be expanded and contracted by injecting and expelling an inflation material inserted through a small incision in the jugular vein is used. In addition to inserting a defect closure means consisting of a device such as the above, and accurately inserting it into the atrial septal defect to close it, it is also possible to easily replace the defect closure structure as the patient grows. It is something to do. Therefore, it is possible to simplify the advanced techniques and equipment required when performing conventional surgery, greatly reduce the surgical invasion inflicted on the living body and the anxiety caused to the patient and his/her family, and This has an excellent effect that can sufficiently eliminate problems such as the psychological influence caused by scars.

[Brief explanation of the drawing]

1 to 12 show a first embodiment of the present invention, FIG. 1 is an assembled external view of the entire device, FIG. 2 is an external view of the balloon in a deflated state, and FIG. 3 is an external end of the connecting tube. Figure 4 is an external view of the cap for closing the end of the tube inside the connecting tube, Figure 5 is an external view of the cap for closing the outer end of the connecting tube, and Figure 6 is the state of connection between each balloon part and the tube. 7 to 12 are diagrams showing the operating process from insertion of the balloon through the incision to completion of closure of the atrial septal defect. Figures 13 to 15 show a second embodiment in which the defect hole closing structure is a balloon-like structure that is integrally connected, and each balloon has a different elongation rate with respect to pressure. It is a figure which shows the transition of a shape step by step. Figures 16 to 22 show the third embodiment, and Figure 16 shows the membranous left atrial insertion part attached to the tip of the injection tubule and the balloon-shaped atrial septum before insertion through the incision. External view of the insertion part and external view of the membranous right atrium insertion part before installation, No. 17-
FIG. 21 is a diagram showing the operation process from insertion to completion of atrial septal defect closure, and FIG. 22 is a partial side sectional view when attachment of the defect closure structure in this embodiment is completed. Figures 23 to 28 show the fourth embodiment, and Figure 23 is an external view of the membranous left atrium insertion part attached to the tip of the injection tubule before insertion through the incision, and a diagram before insertion. An external view of the membranous right atrium insertion part, Figures 24 to 27 are diagrams showing the operation process from insertion to completion of atrial septal defect closure, and Figure 28 is a diagram showing the completion of attachment of the defect closure means in this example. FIG. FIG. 29 is a perspective view showing the fifth embodiment. ■・・・Balloon, 2・・・Balloon, 3
...Balloon, 4...Connection pipe, 5.6
．． 7... Thin tube, 8.9.10... Inflation material injector/discharge device, 11... Thin tube end closed laurel,
12... Camp for closing the connecting pipe, 13...
... Jugular vein, 14... Growth incision line, 15...
...Superficial jugular vein incision, 16...Superior vena cava, 1
7...Superior vena cava, 18...Right atrium, 1
9...Atrial septum, 20...Left atrium, 2
1... Right ventricle, 22... Left ventricle, 23
......Atrial septal defect hole, 24...Hollow catheter, 25...Membrane, 26...Membrane,
27.28... Magnet, 29... Fixed thread, 30.31.32... Needle, 33.34.35...
・Bulkhead part. Agent Patent Attorney Takao Yoshizawa Figure 1 Figure 2 Balloon Figure 2 Figure 3 Figure 5 Figure 4 Figure 6 Figure M7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Fig. 15 Fig. 27 Magnet Fig. 16 Fig. 17 Fig. 18 Fig. 19 Fig. 20 Fig. 28 Magnet Fig. 21 Fig. 22 Fig. 23 Fig. 24 Fig. 25 Fig. 26 Fig. 28 Magnet Fig. 27 Fig. 28

Claims (8)

[Claims] (1) A defect hole closing means in the atrial septum that is attached to the distal end of a tubular means inserted from a vein, and the defect hole closing means is capable of passing through the defect hole through the enlarged left atrium side and the enlarged right atrium side. 1. A transvenous atrial septal defect closure device, characterized in that it is connected via the atrial septum. (2) The transvenous atrial septal defect closure device according to claim 1, wherein all or a portion of the defect closure means is in the form of a balloon that can be expanded by injection of fluid. (3) The transvenous atrial septal defect closure device according to claim 1, wherein the left atrium side enlarged portion and the right atrium side enlarged portion of the defect hole closure means are membrane-like. (4) The transvenous atrial septal defect closure device according to claim (1), wherein the defect closure means uses a combination of a balloon-like structure and a membrane-like structure. (5) Claim (1) wherein the left atrium-side expanded portion, the atrial septum, and the right atrium-side expanded portion of the defect hole closing means are integrally formed, each of which is an independent balloon-like structure with a septum interposed therebetween.
A transvenous atrial septal defect closure device as described. (6) The defect hole closing means is composed of a balloon-like structure in which the left atrium, the atrial septum, and the right atrium are integrally formed and communicate with each other, and each balloon-like structure resists pressure. The transvenous atrial septal defect closure device according to claim 1, which has different elongation rates. (7) The transvenous atrial septum according to claim (1), wherein the left atrium side enlarged part and the right atrium side enlarged part of the defect hole closing means are formed independently, and the atrial septum is the connecting means. Defect hole closure device. (8) Claim (8) wherein the defect hole closing means is such that the left atrial enlarged part and the atrial septum are integrally formed, and are connected to the independently formed right atrial enlarged part by a connecting means ( 1
) Transvenous atrial septal defect closure device.