JPH02250810A - Dental cement composition - Google Patents
Dental cement compositionInfo
- Publication number
- JPH02250810A JPH02250810A JP1073352A JP7335289A JPH02250810A JP H02250810 A JPH02250810 A JP H02250810A JP 1073352 A JP1073352 A JP 1073352A JP 7335289 A JP7335289 A JP 7335289A JP H02250810 A JPH02250810 A JP H02250810A
- Authority
- JP
- Japan
- Prior art keywords
- powder
- calcium phosphate
- dental
- dental cement
- cement composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 33
- 239000003479 dental cement Substances 0.000 title claims abstract description 12
- 239000000843 powder Substances 0.000 claims abstract description 56
- 239000001506 calcium phosphate Substances 0.000 claims abstract description 25
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims abstract description 23
- 229910000389 calcium phosphate Inorganic materials 0.000 claims abstract description 16
- 235000011010 calcium phosphates Nutrition 0.000 claims abstract description 16
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims abstract description 14
- GBNXLQPMFAUCOI-UHFFFAOYSA-H tetracalcium;oxygen(2-);diphosphate Chemical compound [O-2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GBNXLQPMFAUCOI-UHFFFAOYSA-H 0.000 claims abstract description 13
- 238000004898 kneading Methods 0.000 claims abstract description 12
- 239000007788 liquid Substances 0.000 claims abstract description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims abstract description 7
- 229920001577 copolymer Polymers 0.000 claims abstract description 6
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims abstract description 5
- JAHNSTQSQJOJLO-UHFFFAOYSA-N 2-(3-fluorophenyl)-1h-imidazole Chemical compound FC1=CC=CC(C=2NC=CN=2)=C1 JAHNSTQSQJOJLO-UHFFFAOYSA-N 0.000 claims abstract description 5
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 5
- XAAHAAMILDNBPS-UHFFFAOYSA-L calcium hydrogenphosphate dihydrate Chemical compound O.O.[Ca+2].OP([O-])([O-])=O XAAHAAMILDNBPS-UHFFFAOYSA-L 0.000 claims abstract description 5
- LVHBHZANLOWSRM-UHFFFAOYSA-N methylenebutanedioic acid Natural products OC(=O)CC(=C)C(O)=O LVHBHZANLOWSRM-UHFFFAOYSA-N 0.000 claims abstract description 5
- 235000019700 dicalcium phosphate Nutrition 0.000 claims abstract description 3
- 229940095079 dicalcium phosphate anhydrous Drugs 0.000 claims abstract description 3
- RBLGLDWTCZMLRW-UHFFFAOYSA-K dicalcium;phosphate;dihydrate Chemical compound O.O.[Ca+2].[Ca+2].[O-]P([O-])([O-])=O RBLGLDWTCZMLRW-UHFFFAOYSA-K 0.000 claims description 10
- 235000019739 Dicalciumphosphate Nutrition 0.000 claims description 8
- NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 claims description 8
- 229910000390 dicalcium phosphate Inorganic materials 0.000 claims description 8
- 229940038472 dicalcium phosphate Drugs 0.000 claims description 8
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims description 8
- 238000002156 mixing Methods 0.000 claims description 6
- 239000011775 sodium fluoride Substances 0.000 claims description 4
- 235000013024 sodium fluoride Nutrition 0.000 claims description 4
- WUKWITHWXAAZEY-UHFFFAOYSA-L calcium difluoride Chemical compound [F-].[F-].[Ca+2] WUKWITHWXAAZEY-UHFFFAOYSA-L 0.000 claims description 3
- 229910001634 calcium fluoride Inorganic materials 0.000 claims description 3
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 abstract description 5
- 210000003074 dental pulp Anatomy 0.000 abstract description 4
- 239000004568 cement Substances 0.000 abstract description 3
- 210000005036 nerve Anatomy 0.000 abstract description 3
- 150000001875 compounds Chemical class 0.000 abstract description 2
- 230000000704 physical effect Effects 0.000 abstract description 2
- 239000005548 dental material Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 description 21
- 239000002245 particle Substances 0.000 description 12
- 229960001714 calcium phosphate Drugs 0.000 description 9
- 238000011049 filling Methods 0.000 description 6
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 6
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 239000011521 glass Substances 0.000 description 3
- 239000002631 root canal filling material Substances 0.000 description 3
- 208000005888 Periodontal Pocket Diseases 0.000 description 2
- MCMNRKCIXSYSNV-UHFFFAOYSA-N Zirconium dioxide Chemical compound O=[Zr]=O MCMNRKCIXSYSNV-UHFFFAOYSA-N 0.000 description 2
- 238000005299 abrasion Methods 0.000 description 2
- 229910052788 barium Inorganic materials 0.000 description 2
- DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 238000004108 freeze drying Methods 0.000 description 2
- 230000009931 harmful effect Effects 0.000 description 2
- OKJPEAGHQZHRQV-UHFFFAOYSA-N iodoform Chemical compound IC(I)I OKJPEAGHQZHRQV-UHFFFAOYSA-N 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 241000270298 Boidae Species 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- -1 amine compound Chemical class 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000002639 bone cement Substances 0.000 description 1
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 1
- 239000000920 calcium hydroxide Substances 0.000 description 1
- 229910001861 calcium hydroxide Inorganic materials 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 208000002925 dental caries Diseases 0.000 description 1
- 229940023487 dental product Drugs 0.000 description 1
- 150000004683 dihydrates Chemical class 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000005530 etching Methods 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 229910052587 fluorapatite Inorganic materials 0.000 description 1
- 238000005755 formation reaction Methods 0.000 description 1
- 239000003178 glass ionomer cement Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 150000002734 metacrylic acid derivatives Chemical class 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000003504 photosensitizing agent Substances 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- LFULEKSKNZEWOE-UHFFFAOYSA-N propanil Chemical compound CCC(=O)NC1=CC=C(Cl)C(Cl)=C1 LFULEKSKNZEWOE-UHFFFAOYSA-N 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 150000004059 quinone derivatives Chemical class 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 229910052712 strontium Inorganic materials 0.000 description 1
- CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
Abstract
Description
【発明の詳細な説明】
［産業上の利用分野］
本発明は歯科治療で使用されるセメント組成物に関する
。DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to cement compositions used in dental treatment.
［従来の技術］
８！康な歯はその内部に歯髄を有する。歯髄は神経端末
と接しているので、（！ｌｌ１Ｉｉｆｉが熱及び圧力に
敏感であることはよく知られている。従って、歯科用修
復材料としては、歯髄に熱及び圧力を伝達しにくい、即
ち耐熱伝導及び機械的強度に優れるとともに、耐摩耗性
、耐水性、歯との親和性すなわち接着性等の物理的性質
に優れ、更により天然歯に近づける為に透明性、研摩性
等の審美的性質及び生体に対して為害作用がない等の生
体適合性を兼ね備えることが重要である。[Conventional technology] 8! Healthy teeth have pulp inside them. Since the dental pulp is in contact with the nerve terminals, it is well known that (!ll1Iifi) is sensitive to heat and pressure. Therefore, as a dental restorative material, materials that are difficult to transmit heat and pressure to the dental pulp, i.e., heat-resistant It has excellent conductivity and mechanical strength, as well as physical properties such as abrasion resistance, water resistance, and affinity with teeth, i.e., adhesion, as well as aesthetic properties such as transparency and abrasiveness to more closely resemble natural teeth. It is also important to have biocompatibility, such as having no harmful effects on living organisms.
従来、かかる硬化性材料として、硬化後に骨や歯の主成
分であるヒドロキシアパタイトを生成する組成物が提案
されている。例えば、リン酸四カルシウム及び／又はα
−リン酸三カルシウムと水又は有ｆｌｉｔ水溶液の練和
液とよりなる組成物が知られている。Conventionally, compositions that produce hydroxyapatite, which is the main component of bones and teeth, after hardening have been proposed as such hardenable materials. For example, tetracalcium phosphate and/or α
- A composition comprising a kneading solution of tricalcium phosphate and water or a flit aqueous solution is known.
更に、歯科用セメント組成物として多くの提案がなされ
ている。例えば特開昭６３−２０１０３８は、歯科用グ
ラスアイオノマーセメント用に提供されるフルオロアル
ミノシリケートガラス粉末を；特開昭６３−２４３００
９は、アクリレート誘導体またはメタクリレート誘導体
からなる重合性中量体、３８０〜５００ｎｍの波長にお
いて明らかな吸収を示すα−ジケトンまたはキノン誘導
体からなる光増感剤及びアミン化合物の重合促進剤から
成る歯科用光硬化性組成物を；
特開昭６３−２５３０１１は、光重合可能な水酸化カル
シウムセメントから成る歯科用セメント組成物を；及び
特開昭６３−３１６７０９は、可視光の照射により簡便
に重合硬化して、高い機械的性質と優れた耐水性とを有
する光重合性歯科用補綴組成物を提案している。Furthermore, many proposals have been made for dental cement compositions. For example, JP-A-63-201038 discloses a fluoroaluminosilicate glass powder provided for dental glass ionomer cement;
9 is a dental product consisting of a polymerizable intermediate consisting of an acrylate derivative or a methacrylate derivative, a photosensitizer consisting of an α-diketone or quinone derivative that exhibits clear absorption at a wavelength of 380 to 500 nm, and a polymerization accelerator of an amine compound. JP-A No. 63-253011 discloses a dental cement composition comprising a photopolymerizable calcium hydroxide cement; and JP-A No. 63-316709 discloses a photocurable composition that can be easily polymerized and cured by irradiation with visible light. We have proposed a photopolymerizable dental prosthetic composition that has high mechanical properties and excellent water resistance.
本発明者は、天然歯と同じような機械的特性を有し、生
体適合性に優れた硬化性材料を得るべく鋭意研究の結果
、リン酸四カルシウム粉末及び第二リン酸カルシウム・
２水塩粉末及び／又は第二リン酸カルシウム粉末から成
るリン酸カルシウム混合物（ａ）とポリ酸粉末（ｂ）と
から成る粉末成分子Ａ）と
水又はリン酸水溶液から成る練和液（Ｂ）とから成る歯
科用セメント組成物を根管充填材、裏國材、覆準材等の
歯科用修復材として用いた場合、前述の歯科用修復材料
として要求されている特性をすべて満足し且つ、低分子
化合物のＭｕによる歯髄又は神経端末へのダメージがな
いことを見出し、この知見に基づいて本発明を成すに至
った。As a result of intensive research to obtain a curable material with mechanical properties similar to those of natural teeth and excellent biocompatibility, the present inventor discovered tetracalcium phosphate powder and dicalcium phosphate powder.
A powder component element A) consisting of a calcium phosphate mixture (a) consisting of a dihydrate powder and/or a dicalcium phosphate powder and a polyacid powder (b), and a kneading liquid (B) consisting of water or an aqueous phosphoric acid solution. When the dental cement composition is used as a dental restorative material such as a root canal filling material, lining material, and covering material, it satisfies all of the characteristics required for the dental restorative material mentioned above and is a low molecular compound. It was discovered that Mu caused no damage to the dental pulp or nerve terminals, and based on this finding, the present invention was accomplished.
［問題点・を解決するための手段］
本発明の粉末成分（Ａ）はリン酸四カルシウム粉末及び
第二リン酸カルシウム・２水塩粉末及び／又は第二リン
酸カルシウム粉末から成るリン酸カルシウム混合物（ａ
）とポリ酸粉末（ｂ）とから成る。[Means for Solving the Problems] The powder component (A) of the present invention is a calcium phosphate mixture (a
) and polyacid powder (b).
ポリ酸粉末（ｂ）の使用量はリン酸カルシウム混合物（
ａ）に対してｂ／ａ＝ ０．２−０．４ ／１ （ＩＩ
比）の割合である。The amount of polyacid powder (b) used is the same as that of the calcium phosphate mixture (
b/a= 0.2-0.4/1 (II
ratio).
リン酸カルシウム混合物（ａ）に対するポリ酸粉末の割
合（重量比）が０．２未満であると硬化時間が長くなり
且つ硬化物の機械的特性が低下することがある。当該重
量比が０．４を超えると硬化時間が短かくなり実用的で
なく、更に、ペースト又は硬化物のｐＨが低くなるので
、治療部分に疼痛を生ずることがある。If the ratio (weight ratio) of the polyacid powder to the calcium phosphate mixture (a) is less than 0.2, the curing time may become longer and the mechanical properties of the cured product may deteriorate. If the weight ratio exceeds 0.4, the curing time will be short, making it impractical, and furthermore, the pH of the paste or cured product will be low, which may cause pain in the treated area.
リン酸四カルシウム粉末の使用ｆｆ１（ａ、）は第二リ
ン酸カルシウム・２水塩粉末及び／又は第二リン酸カル
シウム粉末のｆｆ１（ａ２）に対して、ａ ／ａ
−１，０−１，３／１ （モル比）の割合である。Use of tetracalcium phosphate powder ff1(a,) is a/a for ff1(a2) of dicalcium phosphate dihydrate powder and/or dicalcium phosphate powder.
-1,0-1,3/1 (molar ratio).
リン酸四カルシウム粉末の使用量が第二リン酸カルシウ
ム・２水塩粉末及び／又は第二リン酸カルシウム粉末の
母に対して１．０モル未満であると、所望の機械的強度
を有さない硬化物が産生ずることがある。リン酸四カル
シウム粉末の使用量が１．３モル以上であると、硬化物
の機械的強酸が低下する傾向にある。If the amount of tetracalcium phosphate powder used is less than 1.0 mol based on the base of dicalcium phosphate dihydrate powder and/or dicalcium phosphate powder, a cured product may not have the desired mechanical strength. It may be produced. When the amount of tetracalcium phosphate powder used is 1.3 mol or more, the mechanical strong acidity of the cured product tends to decrease.
本発明で使用するリン酸四カルシウム粉末の粒径は１−
２０μｍで、その平均粒径は５−１０μｌであることが
好ましい。The particle size of the tetracalcium phosphate powder used in the present invention is 1-
Preferably, the average particle size is 20 μm and the average particle size is 5-10 μl.
粒径１μｍ未満のリン酸四カルシウム粉末が多いと初期
硬化反応が急激に起り、機械的強度の低下した硬化物が
産生ずることがある。粒径２０μｔを超えるリン酸四カ
ルシウム粉末が多く存在すると、硬化物の中に空隙が存
在するので、硬化物の機械的特性が低下する。If there is a large amount of tetracalcium phosphate powder with a particle size of less than 1 μm, the initial curing reaction may occur rapidly, resulting in the production of a cured product with reduced mechanical strength. If a large amount of tetracalcium phosphate powder with a particle size exceeding 20 μt is present, voids will be present in the cured product, and the mechanical properties of the cured product will deteriorate.
本発明で使用する第二リン酸カルシウム・２水塩粉末及
び第二リン酸カルシウム粉末の粒径は０．２−２μｍで
あることが好ましい。粒径２μｍを超える第二リン酸カ
ルシウム・２水塩粉末及び第二リン酸カルシウム粉末が
多いと硬化時間が長くなるので、実用的でない。The particle size of the dibasic calcium phosphate dihydrate powder and dibasic calcium phosphate powder used in the present invention is preferably 0.2-2 μm. If there are a large amount of dicalcium phosphate dihydrate powder and dicalcium phosphate powder with a particle size exceeding 2 μm, the curing time becomes long, which is not practical.
本発明のリン酸カルシウム混合物に５重量％以下の割合
でヒドロキシアパタイト粉末を、及び／又は１重量％以
下の割合でフッ化ナトリウムを添加することも出来る。It is also possible to add hydroxyapatite powder in a proportion of up to 5% by weight and/or sodium fluoride in a proportion of up to 1% by weight to the calcium phosphate mixture according to the invention.
本発明で使用するヒドロキシアパタイト粉末は粒径０．
０５−５μｍのも・のが好ましい。The hydroxyapatite powder used in the present invention has a particle size of 0.
05-5 μm is preferred.
混合するヒドロキシアパタイト粉末はリン酸四カルシウ
ムと第二リン酸カルシウム・２水塩及び／又は第二リン
酸カルシウムのヒドロキシアパタイト化反応の促進剤と
して作用するとともに、シードとして作用して反応によ
り生成したヒドロキシアパタイトの結晶の生成が促進さ
れる。フッ化ナトリウムもまた上記反応の促進剤として
作用する。The hydroxyapatite powder to be mixed acts as a promoter of the hydroxyapatite reaction between tetracalcium phosphate and dicalcium phosphate dihydrate and/or dicalcium phosphate, and also acts as a seed to form hydroxyapatite crystals produced by the reaction. The production of is promoted. Sodium fluoride also acts as a promoter of the above reaction.
歯の主要構成成分であるヒドロキシアパタイト粉末をリ
ン酸カルシウム混合物中に混在させることにより、ヒド
ロキシアパタイト化反応が促進されるとともに、望まし
い形状のヒドロキシアパタイトを生成することが出来且
つ生成した硬化物の機械的特性が歯に一層近づき、充填
物の脱離、脱落及び変色がなく、生体適合性もより一層
優れたものとなるので、ヒドロキシアパタイト粉末を混
合することが好ましい。By mixing hydroxyapatite powder, which is a main component of teeth, in the calcium phosphate mixture, the hydroxyapatite formation reaction is accelerated, hydroxyapatite with a desired shape can be produced, and the mechanical properties of the produced cured product are improved. It is preferable to mix hydroxyapatite powder because the filler will be closer to the tooth, the filling will not come off, fall off, or discolor, and the biocompatibility will be even better.
本発明のリン酸カルシウム混合物にフッ化カルシウムを
５重量％以下の割合で混合することも出来る。フッ化カ
ルシウムは、生成したヒドロキシアパタイトをフルオロ
アパタイトに変換するので、虫歯予防の上からも好まし
い。Calcium fluoride can also be mixed into the calcium phosphate mixture of the present invention in a proportion of 5% by weight or less. Calcium fluoride converts generated hydroxyapatite into fluoroapatite, so it is preferable from the viewpoint of preventing dental caries.
本発明で使用するポリ酸はアクリル酸とイタコン酸との
共重合体であって、分子量がｓ、ｏｏｏ〜３０、Ｇｏｏ
１好ましくは１０．Ｇｏｏ〜１７，０００のものが用い
られる。本発明で使用するポリ酸粉末であるアクリル酸
とイタコン酸との共重合体は、上述のような分子量を有
する共重合体を凍結乾燥法によりその水溶液から固体と
して分離し、粉砕して微粉としたものである。The polyacid used in the present invention is a copolymer of acrylic acid and itaconic acid, and has a molecular weight of s, ooo to 30, goo
1 preferably 10. Goo~17,000 is used. The copolymer of acrylic acid and itaconic acid, which is the polyacid powder used in the present invention, is prepared by separating the copolymer having the above-mentioned molecular weight from an aqueous solution as a solid by freeze-drying, and then pulverizing it into a fine powder. This is what I did.
本発明で使用する練和液は水又はリン酸水溶液である。The kneading liquid used in the present invention is water or an aqueous phosphoric acid solution.
リン酸水溶液中のリン酸の濃度は４０ｎＨ以下であるこ
とが好ましい。The concentration of phosphoric acid in the phosphoric acid aqueous solution is preferably 40 nH or less.
本発明の粉末成分（Ａ）と練和液（Ｂ）は使用直前にト
レー上で練和して用いる。その混合割合は特に限定され
るものではない。根管充填材、裏層材、覆畢材、歯周ポ
ケット充填材、抜歯上充填材等の修ＩＩＮの用途に従っ
て、任意に混合する一般には、得られるペーストの粘度
が１〜１０００ボイズとなるように粉液比を調整すれば
よく、例えば粉末成分（Ａ）の練和液（Ｂ）に対する混
合割合は１−５／１（重量化）が例示し得る。The powder component (A) and the kneading liquid (B) of the present invention are kneaded on a tray immediately before use. The mixing ratio is not particularly limited. Mix as desired according to the purpose of the repair IIN, such as root canal filling material, lining material, lining material, periodontal pocket filling material, tooth extraction filling material, etc. Generally, the viscosity of the resulting paste will be 1 to 1000 boids. For example, the mixing ratio of the powder component (A) to the kneading solution (B) may be 1-5/1 (by weight).
本発明のリン酸ｈルシウム混合物は必要に応じて、硬化
性に著しい悪影響を与えない範囲で他の成分を添加する
ことができる。例えばＸ線造影性を持たせるために、ｆ
ａＭバリウム、バリウムガラス、ストロンチウムガラス
、ジルコニア、ヨードホルム等をリン酸カルシウム温合
物１００ｍｆｆ１部に対して５〜５０重吊部添加するこ
とが出来る。If necessary, other components may be added to the lucium phosphate mixture of the present invention within a range that does not significantly adversely affect the curability. For example, in order to provide X-ray contrast properties, f
5 to 50 weight parts of aM barium, barium glass, strontium glass, zirconia, iodoform, etc. can be added to 1 part of 100 mff of the calcium phosphate warm material.
［効果１
本発明の粉末成分（Ａ）と練和液（Ｂ）とから成る硬化
物は、歯とほぼ同一の機械的特性を有し、即ち、橢械的
強度、耐熱伝ｗ４性、耐摩耗性、耐水性及び歯との親和
性すなわち接着性に優れ、特にエツチング処理又はボン
ディング処理することなく歯質に対する優れた接着性を
有し、且つ生体に対して為害作用がなし１等の生体適合
性を兼ね備えたものである。[Effect 1] The cured product composed of the powder component (A) and the kneading liquid (B) of the present invention has almost the same mechanical properties as teeth, that is, mechanical strength, heat transfer resistance, and It has excellent abrasion resistance, water resistance, and affinity with teeth, that is, adhesion, and has excellent adhesion to tooth structure without any etching or bonding treatment, and has no harmful effects on living organisms and is rated 1st class living organisms. It also has compatibility.
更に、粉末成分（Ａ）と練和液（Ｂ）とから成る硬化物
の硬化時間［ギルモアニードルテスト（ＡＮＳＩ／ＡＤ
Ａ Ｓｐｃ、Ｎｏ、８ ） 、 ３７℃±１℃、 ＲＨ
１００％で測定］は３−１５分であり、１日経過後の硬
化物の直径方向引張強ｒ！Ｌ（３７℃±１℃）は１０Ｈ
Ｐａ以上であって、実用に充分供し得るものである。Furthermore, the curing time of the cured product consisting of the powder component (A) and the kneading liquid (B) [Gilmore needle test (ANSI/AD
A Spc, No. 8), 37℃±1℃, RH
[measured at 100%] is 3-15 minutes, and the diametrical tensile strength r! of the cured product after one day has passed! L (37℃±1℃) is 10H
Pa or higher, which is sufficient for practical use.
本発明のペーストタイプ修復材は、歯の根管充填材、ｌ
Ｉ層材、覆畢材、歯周ポケット充填材、抜歯上充填材等
の歯科用修復材としてのみでなく、骨セメント、骨充噴
材などの整形外科用修復材等の用途にも広く使用するこ
とができる。The paste type restorative material of the present invention is a tooth root canal filling material, l
Widely used not only as dental restorative materials such as I-layer materials, covering materials, periodontal pocket filling materials, and tooth extraction filling materials, but also as orthopedic restorative materials such as bone cement and bone filling materials. can do.
［実施例］
以下、本発明を更に具体的に説明するため、実施例を示
すが、本発明はこれらの実施例に限定されるものではな
い。[Examples] Examples are shown below to further specifically explain the present invention, but the present invention is not limited to these Examples.
実施例１
２１．９６Ｃ１の細かくすり砕いた（粒径：１−２０μ
ｍ、平均粒径ニアμ１１）のリン酸四カルシムウ（！Ｉ
山ソーダ社製、５−Ｃ４Ｐ ） 、８．１６ｇの細かく
すり砕いた（粒径：０．２−２μＩ）の第二リン酸カル
シウム（徳山ソーダ社製、Ｄ ＣＰＡ ） 、０．８７
９の（粒径：０゜０５−２μｌ）のヒトＯキシアパタイ
ト（セントラル硝子社製）、及び０．０６９のフッ化ナ
トリウムを混合してリン酸カルシウム混合物とした。Example 1 Finely ground 21.96C1 (particle size: 1-20μ
m, average particle size near μ11) of tetracalcium phosphate (!I
Yama Soda Co., Ltd., 5-C4P), 8.16 g finely ground (particle size: 0.2-2 μI) dicalcium phosphate (Tokuyama Soda Co., Ltd., DCPA), 0.87
A calcium phosphate mixture was prepared by mixing 9 parts (particle size: 0°05-2 μl) of human oxygen xiapatite (manufactured by Central Glass Co., Ltd.) and 0.069 parts of sodium fluoride.
このリン酸カルシウム混合物１０重吊部に対し、アクリ
ル酸とイタコン酸との共重合体（分子量：約１５，００
０＞を凍結乾燥して得た粉末を２．５重量部Ｉの割合で
加えて粉末成分（Ａ）を調整した。A copolymer of acrylic acid and itaconic acid (molecular weight: about 15,000
A powder component (A) was prepared by adding 2.5 parts by weight of powder obtained by freeze-drying 0>.
練和液としては水を用いた。Water was used as the kneading liquid.
得られた粉末成分（Ａンと練和液（Ｂ）をトレー上で混
練し、ステンレススチールの鋳型（６ＭＤ Ｘ３順Ｈ）
に充填した。３７℃±１℃で１日貯蔵した後、万能試験
機（ミネベア社製）を用いて１０ｒＩＩ！／分のクロス
ヘツド速度で圧縮荷重をかけて直径方向引張強度（ＤＴ
Ｓ）を測定した結果、１２．３７ＨＰａであった。The obtained powder components (A) and kneading liquid (B) were kneaded on a tray, and molded into a stainless steel mold (6MD x 3 order H).
was filled. After storing for one day at 37°C ± 1°C, 10rII! The diametrical tensile strength (DT
As a result of measuring S), it was 12.37 HPa.
硬化時間をギルモアニードルテスト（ＡＮＳＩ／＾０＾
Ｓｐｃ、Ｎｏ、８＞により３７℃±１℃、ＲＨ１００％
で測定した結果、７分であった。Curing time was determined by Gilmore needle test (ANSI/^0^
37℃±1℃, RH100% by Spc, No. 8>
The measurement result was 7 minutes.
代１！Ｉ：人１１月Ｉｌ： Ｉｉｉ 山武1 generation! I: November Il: Iii Yamatake
Claims (6)
ム・２水塩粉末及び／又は第二リン酸カルシウム粉末か
ら成るリン酸カルシウム混合物（ａ）とポリ酸粉末（ｂ
）とから成る粉末成分（Ａ）と水又はリン酸水溶液から
成る練和液（Ｂ）とから成る歯科用セメント組成物。(1) Calcium phosphate mixture (a) consisting of tetracalcium phosphate powder, dicalcium phosphate dihydrate powder and/or dicalcium phosphate powder (b) and polyacid powder (b)
A dental cement composition comprising a powder component (A) consisting of ) and a kneading liquid (B) consisting of water or an aqueous phosphoric acid solution.
体粉末である請求項１記載の歯科用セメント組成物。(2) The dental cement composition according to claim 1, wherein the polyacid powder is a copolymer powder of acrylic acid and itaconic acid.
ルシウム混合物（ａ）に対する混合割合（重量比）がｂ
／ａ＝０．２−０．４／１である請求項１記載の歯科用
セメント組成物。(3) The mixing ratio (weight ratio) of the polyacid powder (b) in the powder component (A) to the calcium phosphate mixture (a) is b
The dental cement composition according to claim 1, wherein /a=0.2-0.4/1.
シウム粉末（ａ＿１）の第二リン酸カルシウム・２水塩
粉末及び／又は第二リン酸カルシウム粉末（ａ＿２）に
対する混合割合（モル比）がａ＿１／ａ＿２＝１−１．
３／１である請求項１記載の歯科用セメント組成物。(4) The mixing ratio (molar ratio) of tetracalcium phosphate powder (a_1) to dibasic calcium phosphate dihydrate powder and/or dibasic calcium phosphate powder (a_2) in calcium phosphate mixture (a) is a_1/a_2=1 -1.
The dental cement composition according to claim 1, which has a ratio of 3/1.
ヒドロキシアパタイト粉末及び／又は１重量％以下のフ
ッ化ナトリウム粉末を添加してなる請求項１記載の歯科
用セメント組成物。(5) The dental cement composition according to claim 1, wherein 5% by weight or less of hydroxyapatite powder and/or 1% by weight or less of sodium fluoride powder are added to the calcium phosphate mixture (a).
フッ化カルシウム粉末を添加してなる請求項１記載の歯
科用セメント組成物。(6) The dental cement composition according to claim 1, wherein 5% by weight or less of calcium fluoride powder is added to the calcium phosphate mixture (a).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1073352A JPH02250810A (en) | 1989-03-24 | 1989-03-24 | Dental cement composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1073352A JPH02250810A (en) | 1989-03-24 | 1989-03-24 | Dental cement composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH02250810A true JPH02250810A (en) | 1990-10-08 |
Family
ID=13515688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1073352A Pending JPH02250810A (en) | 1989-03-24 | 1989-03-24 | Dental cement composition |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH02250810A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005132112A (en) * | 2003-10-28 | 2005-05-26 | Hewlett-Packard Development Co Lp | Resin-modified inorganic phosphate cement for solid free-form fabrication |
| CN100371409C (en) * | 2003-06-24 | 2008-02-27 | 惠普开发有限公司 | Cement system including a binder for use in freeform fabrication |
| WO2014050924A1 (en) * | 2012-09-28 | 2014-04-03 | クラレノリタケデンタル株式会社 | Curable composition for dentistry, and method for producing same |
| WO2015133149A1 (en) * | 2014-03-06 | 2015-09-11 | 株式会社メディカルユーアンドエイ | Method for controlling work time for forming shape of biphasic self-setting calcium phosphate |
-
1989
- 1989-03-24 JP JP1073352A patent/JPH02250810A/en active Pending
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100371409C (en) * | 2003-06-24 | 2008-02-27 | 惠普开发有限公司 | Cement system including a binder for use in freeform fabrication |
| JP2005132112A (en) * | 2003-10-28 | 2005-05-26 | Hewlett-Packard Development Co Lp | Resin-modified inorganic phosphate cement for solid free-form fabrication |
| US7455805B2 (en) | 2003-10-28 | 2008-11-25 | Hewlett-Packard Development Company, L.P. | Resin-modified inorganic phosphate cement for solid freeform fabrication |
| WO2014050924A1 (en) * | 2012-09-28 | 2014-04-03 | クラレノリタケデンタル株式会社 | Curable composition for dentistry, and method for producing same |
| CN104812358A (en) * | 2012-09-28 | 2015-07-29 | 可乐丽则武齿科株式会社 | Curable composition for dentistry, and method for producing same |
| JPWO2014050924A1 (en) * | 2012-09-28 | 2016-08-22 | クラレノリタケデンタル株式会社 | Dental curable composition and method for producing the same |
| US9427381B2 (en) | 2012-09-28 | 2016-08-30 | Kuraray Noritake Dental Inc. | Dental curable composition, and method for producing same |
| WO2015133149A1 (en) * | 2014-03-06 | 2015-09-11 | 株式会社メディカルユーアンドエイ | Method for controlling work time for forming shape of biphasic self-setting calcium phosphate |
| JPWO2015133149A1 (en) * | 2014-03-06 | 2017-04-06 | 株式会社メディカルユーアンドエイ | Control method of working time for shaping the shape of biphasic spontaneously hardening type calcium phosphate |
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