JPH02204033A - Laminate - Google Patents

Abstract

PURPOSE:To obtain a packing material for liquid transporting bag, prominent in flexibility as well as gas barrier properties and durable upon heating germicidal process by a method wherein a laminate is constituted of the outermost layer of a specified thermoplastic elastomer layer, a polyvinylidene chloride resin layer, a seal layer consisting of polyolefin resin and a bonding layer. CONSTITUTION:The outermost thermoplastic elastomer layer 1 is provided with flexibility, heat resistant properties, excellent transparency and water vapor barrier properties while prevents the fusion welding between bags as well as the invasion of water vapor upon autoclave heating germicidal process. The thermoplastic elastomer, having the elastic modulus in tension of 500-5,000 kgf/cm<2> and the Vicat softening point of 100 deg.C or higher, is used. A polyvinylidene resin layer 2 holds gas barrier properties. Polyolefin resin, used for a seal layer 3, is the individual polymer of polyethylene, polypropylene, polybuthane and the like, the copolymer of them or the mixed composition of the other resin and prominent in sealing property. Bonding layers 4, 4' are constituted of adhesive resin when they are co-extruded or are constituted of a bonding agent when they are dry laminates while they bond respective layers.

Description

Detailed Description of the Invention [Industrial Field of Application] The present invention has excellent flexibility and gas barrier properties, and also has heat resistance and whitening resistance that can withstand heat sterilization treatment, as well as a reduction in gas barrier properties even after heat sterilization treatment. The present invention relates to a laminate for a high gas barrier infusion bag that does not cause the

[Conventional technology]

Retort heat sterilization and autoclave heat sterilization have been conventionally used to completely kill and remove microorganisms that cause deterioration and spoilage of foods and medicines. The packaging material used for this application is a multilayer film based on glass or AI foil. However, the At foil was opaque and it was not possible to inspect changes in the contents after heat treatment.

In addition, soft vinyl chloride has traditionally been used for infusion bags as a material that is flexible, has excellent heat resistance and transparency, but it can only be used at room temperature, and when heat sterilized in an autoclave, plasticizers and other additives may be added. There are problems with substance elution and whitening resistance, and a material that can withstand use has not been obtained. Furthermore, although various polypropylene materials have been studied, none have been sufficiently satisfactory in terms of flexibility, heat resistance, and whitening resistance. At medical institutions, amino acids, vitamins, etc. are added and prepared immediately before administering an intravenous drip to a patient, but due to rationalization of work schedules, there is a growing demand for pre-prepared IV drips from manufacturers. In that case, the infusion bathoge will need gas barrier properties.

Since the above-mentioned materials have poor gas barrier properties, they cannot be satisfactorily used alone in that respect as well. [11 Films that are a combination of polyester film or polypropylene film and gas barrier film are commercially available, but they have no flexibility and cannot be used for infusion bags.

(Problem to be solved by the invention) The present invention has excellent flexibility and gas barrier properties, heat resistance and whitening resistance that can withstand heat sterilization treatment, and stable gas barrier properties that were not available with conventional heat-resistant packaging materials. To provide a packaging material R4 for an infusion bag having a high gas barrier property.

[Means to solve the problem]

The present invention has a tensile modulus of 500 to 5000 kgf/cj
and a laminate comprising at least a thermoplastic elastomer layer having a Vicat softening point of 100°C or more as the outermost layer, a polyvinylidene chloride resin layer, a sealing layer made of a polyolefin resin, and an adhesive layer. It is.

The thermoplastic elastomer used in the present invention has a tensile modulus of 500 to 5000 kgf/cd and Vica
The temperature of the softening point is 00°C or higher.

If the tensile modulus is less than 50Qkgf/cd, it will be too flexible and cause trouble during sheet processing.
At gf/e- or higher, the flexibility required for the infusion bag is impaired. In addition, if the VicaL softening point is 100'C or less, the bags will be thermally fused together during autoclave heat sterilization.

Polyolefin resins are mixture compositions of homopolymers such as polyethylene, polypropylene, polybutene, copolymers thereof, and other resins in which polyolefin resins are the main component.

Further, the adhesive layer is an adhesive resin in the case of coextrusion, and an adhesive in the case of dry lamination.

[For production]

FIG. 1 is a cross-sectional view of one specific example of the laminate according to the present invention, in which numeral 1 is the outermost thermoplastic elastomer layer, which maintains flexibility and heat resistance, and desirably has an excellent transparency and water vapor barrier. It also prevents the bags from thermally adhering to each other during autoclave heat sterilization, and also prevents water vapor from entering, thereby preventing deterioration of gas barrier properties and whitening.

2 is a polyvinylidene chloride resin layer which is a gas barrier layer, and a saponified ethylene/vinyl acetate copolymer is not desirable because the gas barrier properties are degraded by water vapor that enters during autoclave heat sterilization treatment.

3 is a sealing layer, which is an olefin resin with excellent sealing properties, and 4.4 is an adhesive layer for bonding each layer.

〔Example〕

A laminate was prepared using the following materials and had the configuration shown in Table 1, and its properties as a high gas barrier infusion bag were measured.In order to make the effects of the present invention clearer, comparative examples are also shown.

■ Outermost Layer Vicat Softening Point f Liesde Wisteria-based Nilaston- 1°-Stmann+: PCCE9966f Lyolefin-based Elasto 7- Jusumu Kagaku Kogyo: TPE907 Nine Elas 4 M-Sli? Run ELY2694 Dali Ju Pyrene Tabulation Chemistry 1 + PHIO15 Polyethylene Resident Chemical [Industry: F208-1 +65'c 130°C 175°C 145'c 96'C ■f Vinyritine Chloride Resin First Chemical Company: glan468 So 1<- company: 1XAN pvg8゜Asahi Kasei T-gyo: f run υB Tensile modulus 1260 kgf/cd ■Seal Layer f rib n pyrene resin Dainippon Plus f Kukusu MK
-1 straight line #, density IIJ1fk> Mitsui Petrochemical Industries 20201 low density I'Jlfkn Resident Chemical Industry L
2113200kgf/cd 3800kgf/cd 13000kgf/cd 2200kgf/cd ■Adhesive layer Horib■Pyrene system Mitsui Petrochemical Industries 7F? -QF
SOOl tyrene/α/olefin copolymer system 7Fmer AT469
CAa [f Liethylene-based Mitsubishi Yuka
(Tick I+-100F urethane adhesive [Effects of the invention]) By using the laminate of the present invention, it maintains excellent heat resistance and flexibility that could not be obtained conventionally, and also has excellent transparency and gas barrier properties. This makes it possible to create a high gas barrier M liquid buff, which can greatly contribute to the medical field.

■H-Renyl Vinyl Acetate Copolymer 'J'n compound Kurile = Ever-Katsu ε-151

[Brief explanation of the drawing]

FIG. 1 is a sectional view of one embodiment of a laminate according to the present invention.

Claims (1)

[Claims] (1) Tensile modulus is 500 to 5000 kgf/cm^2
and a laminate comprising at least a thermoplastic elastomer layer having a Vicat softening point of 100°C or more as the outermost layer, a polyvinylidene chloride resin layer, a sealing layer made of a polyolefin resin, and an adhesive layer. .