JPH02181652A - Image display device of automatic blood image classifying device - Google Patents
Image display device of automatic blood image classifying deviceInfo
- Publication number
- JPH02181652A JPH02181652A JP31789A JP31789A JPH02181652A JP H02181652 A JPH02181652 A JP H02181652A JP 31789 A JP31789 A JP 31789A JP 31789 A JP31789 A JP 31789A JP H02181652 A JPH02181652 A JP H02181652A
- Authority
- JP
- Japan
- Prior art keywords
- image
- circuit
- camera
- color
- crt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004369 blood Anatomy 0.000 title claims description 10
- 239000008280 blood Substances 0.000 title claims description 10
- 210000000601 blood cell Anatomy 0.000 claims abstract description 17
- 239000003086 colorant Substances 0.000 abstract description 11
- 230000000007 visual effect Effects 0.000 abstract description 4
- 230000033458 reproduction Effects 0.000 abstract 2
- 235000019646 color tone Nutrition 0.000 abstract 1
- 230000006866 deterioration Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 238000010586 diagram Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 210000003743 erythrocyte Anatomy 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 210000004940 nucleus Anatomy 0.000 description 2
- 210000000805 cytoplasm Anatomy 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Closed-Circuit Television Systems (AREA)
Abstract
Description
【発明の詳細な説明】
〔産業上の利用分野〕
本発明は、画像処理を利用した血液像自動分類装置に係
り、特に、血球像をCRTデイスプレィ上に表示する際
に好適な画像表示装置に関する。DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to an automatic blood image classification device using image processing, and particularly to an image display device suitable for displaying blood cell images on a CRT display. .
従来の装置では、画像表示用のCRTに、画像処理用の
信号が直接入力され狭帯域フィルタを用いていることの
補正、γ特性の補正等が行われていない。そのため核は
実像色よりも青く、赤血球は実像色よりも赤く表示され
、顕微鏡による目視像との間に違和感があった。In the conventional apparatus, a signal for image processing is directly input to a CRT for image display, and correction for the use of a narrow band filter, correction for γ characteristics, etc. are not performed. As a result, the nucleus appeared bluer than the real image color, and the red blood cell appeared redder than the real image color, creating a sense of incongruity between the two images and the visual image obtained using a microscope.
上記従来技術は、血液像を分類するための画像信号と、
CRTに表示する信号が同一のものであり1分類端度を
向上させるため血球の特徴が最も顕著となるように置か
れた狭帯域フィルターなどCRT上への血球像の色再現
を劣化させている要因に対しての配慮がなされておらず
、顕微鏡による目視像とCRT上に再現された血球像の
色調が異なる。そのため、顕微鏡による目視に慣れた使
用者に違和感を与え、CRT上の血球像の色調で目視分
類する場合に支障をきたすという開運があった。The above conventional technology uses an image signal for classifying blood images;
The signals displayed on the CRT are the same, and in order to improve the accuracy of classification, narrow band filters are placed so that the characteristics of the blood cells are most noticeable, which deteriorates the color reproduction of the blood cell image on the CRT. No consideration is given to these factors, and the color tone of the visual image under a microscope and the blood cell image reproduced on a CRT are different. As a result, users accustomed to visual inspection using a microscope may feel uncomfortable, and this may pose a problem when visually classifying blood cells based on the color tone of blood cell images on a CRT.
本発明の目的は、この顕微鏡による目視像とCRT上に
再現される像との間の色調の相異を、光学系の変更を行
わずに、かつ、分類精・度の低下をきたすことなく画像
信号の処理を行って改善することにある。The purpose of the present invention is to correct the difference in color tone between the visual image by a microscope and the image reproduced on a CRT without changing the optical system and causing a decrease in classification accuracy. The aim is to process and improve image signals without any problems.
上記目的は、血液像自動分類装置においては。 The above purpose is achieved in a blood image automatic classification device.
カラーCRTに再現される画像の色は限られており、大
別すると、白血球の核、細胞質2種類、か粒2種類、赤
血球、背景の7色となり、これらの血球色を測色学的計
算によって3原色の比(R:G:B)を求め、狭帯域フ
ィルターを使ったTVカメラの画像信号(R“、G’、
B’)の比が、全ての像の色に均当に近くなるようにR
’ 、G’B″′に式(1)に示したマトリクス演算を
行い、さらに、カラーCRTのγ特性を補性する回路(
式(2))と組み合わせて、より見やすい色再現となっ
て達成される。The colors of images reproduced on a color CRT are limited, and can be roughly divided into seven colors: the white blood cell nucleus, two types of cytoplasm, two types of granules, red blood cells, and the background. These blood cell colors are calculated using colorimetric calculations. The ratio of the three primary colors (R:G:B) is determined by
R so that the ratio of B') is evenly close to the color of all images.
A circuit (
In combination with Equation (2)), more visible color reproduction is achieved.
本回路は、血液像自動分類装置など画像処理用のTVカ
メラから得られた画像信号を実像色と等しい色がCRT
上に再現されるように処理する。This circuit converts image signals obtained from a TV camera for image processing, such as an automatic blood image classification device, into a CRT with the same color as the real image color.
Process as reproduced above.
−段目のマトリクス演算回路は、画像処理用のTVカメ
ラからの映像出力信号を、実像色と等しい色が再現され
るような信号の比に変換し、次段のγ補正回路に−加え
る。γ補正回路は、CRTのγ特性を補正するとともに
、R,G、B信号のγ補正の程度を個々に与え、画像の
特定部位のコントラストを向上させ、より見やすい画像
にする働きをする。つまり、第2−図のγ補正特性にお
いて、画像信号のレベルの低い部分では、aの入力電圧
にa′の出力が得られ、γ補正を大にすることにより画
像のコントラストが向上する。一方、レベルの高い画像
間のコントラストは、bからb′となってγ補正が小さ
い方が、コントラストが高くなり、γ補正の程度によっ
て、特定部分力画像のコントラストを向上させることが
できる6以上2つの回路により、実像色に近い色が再現
される。The -th stage matrix calculation circuit converts the video output signal from the TV camera for image processing into a signal ratio that reproduces a color equal to the real image color, and applies it to the next stage γ correction circuit. The gamma correction circuit serves to correct the gamma characteristics of the CRT, and to individually apply gamma correction degrees to the R, G, and B signals, thereby improving the contrast of a specific part of the image and making the image more viewable. That is, in the γ correction characteristic shown in FIG. 2, in a portion where the level of the image signal is low, an output of a' is obtained for an input voltage of a, and the contrast of the image is improved by increasing the γ correction. On the other hand, the contrast between high-level images goes from b to b', and the smaller the γ correction, the higher the contrast, and depending on the degree of γ correction, the contrast of a specific partial force image can be improved by 6 or more. The two circuits reproduce colors close to the real image colors.
以下、本発明の一実施例を第1図、第3図により説明す
る。第1図は、血液像自動分類装置の画像表示系の概略
図である。顕微鏡2により拡大された標本1の画像情報
は、血球の特徴を得るための狭帯域フィルターF p、
、 F a 、 F a6 を通ってTVカメラの
撮像管に入り、電気信号に変換される。この信号R’
、G’ 、B’により血球の分類を行う。この信号をC
RTに入力する際に、ミキシング回路8γ補正回路9を
通して、色再現の補正を行う。An embodiment of the present invention will be described below with reference to FIGS. 1 and 3. FIG. 1 is a schematic diagram of an image display system of an automatic blood image classification device. The image information of the specimen 1 magnified by the microscope 2 is passed through a narrow band filter F p to obtain characteristics of blood cells.
, F a , F a6 and enters the image pickup tube of the TV camera, where it is converted into an electrical signal. This signal R'
, G', and B'. This signal is C
When inputting to RT, color reproduction is corrected through a mixing circuit 8 and a gamma correction circuit 9.
色再現の補正は、第3図を用い説明する。画像処理用の
信号R’ 、G”、B″′は、オペアンプ16、ミキシ
ング係数を決定する抵抗15等で構成されたミキシング
回路によって色再現の補正が加えられる。その次に、C
RT18のγ特性を補正する回路17に入力される。ミ
キシング係数は、各血球色が一様に実像色に近くなるよ
う決定し、γ補正の大きさは、血球像のコントラストが
向上し、かつ、色再現の劣化がないように、ミキシング
回路との間で調整した。Correction of color reproduction will be explained using FIG. 3. The image processing signals R', G", B"' are corrected for color reproduction by a mixing circuit composed of an operational amplifier 16, a resistor 15 for determining a mixing coefficient, and the like. Next, C
The signal is input to a circuit 17 that corrects the γ characteristic of the RT 18. The mixing coefficient is determined so that each blood cell color is uniformly close to the real image color, and the magnitude of γ correction is determined based on the mixing circuit so that the contrast of the blood cell image is improved and color reproduction is not degraded. Adjusted between.
このミキシング回路、γ補正回路を加えることにより、
CRTに再現される血球色は、顕微鏡による目視像の色
調と等しくなり、違和感が解消された。By adding this mixing circuit and γ correction circuit,
The color of the blood cells reproduced on the CRT was equal to the color tone of the image visually observed with a microscope, and the discomfort was eliminated.
本発明によれば、画像処理用のTVカメラ出力信号を演
算することだけで、血球色の色再現性を向上させること
ができ、CRT表示専用のTVカメラを別途設定する必
要がなく、安価に画像の色再現性を向上させるのに役立
つ。According to the present invention, the color reproducibility of blood cell color can be improved simply by calculating the TV camera output signal for image processing, and there is no need to separately set up a TV camera exclusively for CRT display, making it possible to reduce costs. Helps improve image color reproduction.
第1図は本発明の一実施例のブロックダイアグラムを示
す図、第2図はB信号のγ特性による輝度の変化量を示
す図、第3図はミキシング回路及びγ補正回路図である
。
1・・・標本、2・・・顕微鏡、5・・・TVカメラ、
8・・・ミキシング回路、9・・・γ補正回路、10・
・A/D変換器、11・・・CPU、12・・・CRT
、13・・・光源。
第1FIG. 1 is a block diagram of an embodiment of the present invention, FIG. 2 is a diagram showing the amount of change in luminance due to the γ characteristic of the B signal, and FIG. 3 is a mixing circuit and γ correction circuit diagram. 1...Specimen, 2...Microscope, 5...TV camera,
8... Mixing circuit, 9... γ correction circuit, 10.
・A/D converter, 11...CPU, 12...CRT
, 13... light source. 1st
Claims (1)
カメラで撮像し、前記TVカメラの出力信号をA/D変
換したデータを用いて血球像を分類し、かつ、前記TV
カメラの出力信号で、カラー画像表示装置に表示する血
液像自動分類装置において、前記TVカメラの出力信号
の色補正回路を設けたことを特徴とする血液像自動分類
装置における画像表示装置。 2、前記色補正回路にγ補正回路を追加したことを特徴
とする血液像自動分類装置における画像表示装置。 3、前記色補正回路はTVカメラの3つの出力信号の各
々に対して重み係数をかけ、その重み係数がかけられた
画像信号を加算することを特徴とする血液像自動分類装
置における画像表示装置。 4、前記γ補正回路は、非線形な入出力特性をもつた増
幅回路であることを特徴とする血液像自動分類装置にお
ける画像表示装置。[Claims] 1. After enlarging the image of the specimen using a light source and a microscope, the image is displayed on a TV.
Classifying blood cell images using data obtained by capturing an image with a camera and A/D converting the output signal of the TV camera, and
An image display device for an automatic blood image classification device that displays an output signal of a camera on a color image display device, characterized in that a color correction circuit for the output signal of the TV camera is provided. 2. An image display device for an automatic blood image classification apparatus, characterized in that a γ correction circuit is added to the color correction circuit. 3. An image display device in an automatic blood image classification apparatus, wherein the color correction circuit multiplies each of the three output signals of the TV camera by a weighting coefficient, and adds the image signals multiplied by the weighting coefficients. . 4. An image display device in an automatic blood image classification apparatus, wherein the γ correction circuit is an amplifier circuit with nonlinear input/output characteristics.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP31789A JPH02181652A (en) | 1989-01-06 | 1989-01-06 | Image display device of automatic blood image classifying device |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP31789A JPH02181652A (en) | 1989-01-06 | 1989-01-06 | Image display device of automatic blood image classifying device |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH02181652A true JPH02181652A (en) | 1990-07-16 |
Family
ID=11470530
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP31789A Pending JPH02181652A (en) | 1989-01-06 | 1989-01-06 | Image display device of automatic blood image classifying device |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPH02181652A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994011841A1 (en) * | 1992-11-06 | 1994-05-26 | Quatro Biosystems Limited | Method and apparatus for image analysis |
-
1989
- 1989-01-06 JP JP31789A patent/JPH02181652A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994011841A1 (en) * | 1992-11-06 | 1994-05-26 | Quatro Biosystems Limited | Method and apparatus for image analysis |
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