JPH01284304A - Separation treatment with membrane - Google Patents
Separation treatment with membraneInfo
- Publication number
- JPH01284304A JPH01284304A JP11208488A JP11208488A JPH01284304A JP H01284304 A JPH01284304 A JP H01284304A JP 11208488 A JP11208488 A JP 11208488A JP 11208488 A JP11208488 A JP 11208488A JP H01284304 A JPH01284304 A JP H01284304A
- Authority
- JP
- Japan
- Prior art keywords
- membrane
- particles
- bioreactor
- separation
- deposition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012528 membrane Substances 0.000 title claims abstract description 45
- 238000000926 separation method Methods 0.000 title claims description 26
- 239000002245 particle Substances 0.000 claims abstract description 29
- 239000003463 adsorbent Substances 0.000 claims description 13
- 238000001179 sorption measurement Methods 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 6
- 241000894006 Bacteria Species 0.000 abstract description 6
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract description 6
- 230000000274 adsorptive effect Effects 0.000 abstract description 6
- 239000011148 porous material Substances 0.000 abstract description 4
- 239000004925 Acrylic resin Substances 0.000 abstract description 3
- 229920000178 Acrylic resin Polymers 0.000 abstract description 3
- 230000008021 deposition Effects 0.000 abstract description 3
- PNEYBMLMFCGWSK-UHFFFAOYSA-N Alumina Chemical compound [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 abstract description 2
- 230000000903 blocking effect Effects 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- 238000004140 cleaning Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 6
- 239000005416 organic matter Substances 0.000 description 6
- 239000000843 powder Substances 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 238000011001 backwashing Methods 0.000 description 3
- 238000007796 conventional method Methods 0.000 description 3
- 235000014655 lactic acid Nutrition 0.000 description 3
- 239000004310 lactic acid Substances 0.000 description 3
- 230000004907 flux Effects 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000001464 adherent effect Effects 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 239000012510 hollow fiber Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 229920005597 polymer membrane Polymers 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
Landscapes
- Separation Using Semi-Permeable Membranes (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
Description
【発明の詳細な説明】
〔産業上の利用分野〕
本発明は、膜分離処理方法、特に腔型バイオリアクタに
おける分離膜表面への有機物等の付着堆積とそれによる
目詰まりを防止し、高透過流束を維持しながら膜分離処
理を行う方法に関する。Detailed Description of the Invention [Industrial Application Field] The present invention is directed to a membrane separation treatment method, particularly in a cavity-type bioreactor, which prevents the adhesion and accumulation of organic substances on the surface of a separation membrane and the resulting clogging, and achieves high permeability. This invention relates to a method for performing membrane separation processing while maintaining flux.
〔従来の技術］
腔型バイオリアクタは、膜の分離機能を利用して、リア
クタ内の固定化微生物菌体または酵素を触媒とする反応
物質（基質）の分解、変換、合成等の反応や微生物菌体
の培養と、その生成物の分離等を同時に達成する生体反
応システムであり、その操作法としていくつかの方式が
行われており、また膜体は、分離される粒子のサイズに
応じた透過孔径を有する各種高分子膜、セラミック焼成
膜等が、スパイラル型、中空糸型、細管型、平板型等の
モジュールで使用されている。[Prior art] Cavity-type bioreactors utilize the separation function of membranes to perform reactions such as decomposition, conversion, and synthesis of reactants (substrates) using immobilized microbial cells or enzymes in the reactor, as well as microorganisms. It is a biological reaction system that simultaneously achieves the cultivation of bacterial cells and the separation of its products.Several methods are used for its operation, and the membrane body is different depending on the size of the particles to be separated. Various polymer membranes, fired ceramic membranes, and the like having permeable pore sizes are used in modules such as spiral type, hollow fiber type, capillary type, and flat plate type.
腔型バイオリアクタのシステム効率を高めるためには、
膜体が所定の分離機能を有するとともに、長期に亘って
その分離機能が維持されることが必要である。To increase the system efficiency of cavity bioreactors,
It is necessary for the membrane body to have a predetermined separation function and to maintain that separation function over a long period of time.
しかるに、その分離膜面には、リアクタへの供給液中に
添加された基質やりアクタ内の生体反応により生成した
有機物等が付着ないし吸着することによる目詰まり・透
過性能の低下が生じ易い。However, the surface of the separation membrane tends to be clogged and the permeation performance deteriorates due to adhesion or adsorption of substrates added to the liquid supplied to the reactor, organic substances generated by biological reactions within the reactor, and the like.
このため、分離膜面の付着・吸着物（以下、「付着物」
）を膜面か、ら離脱除去するための洗浄操作（逆洗浄等
）の頻繁な実施を余儀なくされている。For this reason, substances attached/adsorbed on the surface of the separation membrane (hereinafter referred to as “adherents”)
) must be removed from the membrane surface frequently by cleaning operations (backwashing, etc.).
本発明は、分離膜面への有機物等の付着堆積を抑制し、
長期に亘って膜面の洗浄処理を必要とせずに高透過性能
を維持させながら膜分離処理を行うことができるように
したものである。The present invention suppresses the adhesion and deposition of organic substances etc. on the separation membrane surface,
This makes it possible to perform membrane separation processing while maintaining high permeability without requiring cleaning of the membrane surface over a long period of time.
〔課題を解決するための手段および作用〕本発明の膜分
離処理方法は、膜壁バイオリアクタ内の液中に吸着性粒
子を分散懸濁させ、分離膜表面の付着物を、該吸着性粒
子の吸着力により分離膜面より離脱除去することを特徴
としている。[Means and effects for solving the problem] The membrane separation treatment method of the present invention involves dispersing and suspending adsorbent particles in a liquid in a membrane wall bioreactor, and removing deposits on the surface of the separation membrane by removing the adsorbent particles. It is characterized by the fact that it is separated and removed from the separation membrane surface by the adsorption force of .
本発明におけるバイオリアクタ内の液中に添加される吸
着性粒子としては、例えば活性炭微粉末やアクリル樹脂
微粉末等が挙げられる。これらの微粉末は、強力な吸着
作用により、分離膜面の付着物を膜面より離脱させ、粒
子表面に吸着保持する。吸着性粒子は、分離膜の透過孔
内への侵入・目詰まりを生じない範囲で微細なほど有効
であるが、例えば粒径Ｏ０１〜５Ｍの活性炭粉末、粒径
０．２〜３０μｍのアクリル樹脂微粉末等は、入手容易
で、良好な吸着作用が得られる粒子として好適に使用さ
れる。これらの吸着性粒子は異種同士を混合使用してよ
い。Examples of the adsorbent particles added to the liquid in the bioreactor in the present invention include activated carbon fine powder and acrylic resin fine powder. These fine powders use a strong adsorption action to remove deposits from the separation membrane surface and adsorb and hold them on the particle surface. The finer the adsorptive particles are, the more effective they are as long as they do not invade or clog the permeation pores of the separation membrane. Fine powder and the like are easily available and are preferably used as particles that provide a good adsorption effect. These adsorptive particles may be used in combination of different types.
吸着性粒子の添加量は液中の有機物の濃度や膜面への付
着傾向の程度等に応じて適宜増減調節される。The amount of adsorbent particles added is adjusted to increase or decrease as appropriate depending on the concentration of organic matter in the liquid, the degree of tendency of adhesion to the membrane surface, etc.
分離膜面の有機物を膜面から離脱させて粒表面に吸着保
持した吸着性粒子の一部は、その膜面上に付着・堆積す
ることがあるが、その場合にも、有機物が直接分離膜面
に付着・堆積している場合と異なって、液の膜面線速に
より容易に剥離するので分離膜の透過性能の維持に実質
的な妨げとなることはない。Some of the adsorbent particles that are adsorbed and retained on the particle surface after removing the organic matter from the separation membrane surface may adhere and accumulate on the membrane surface, but even in such cases, the organic matter is directly absorbed by the separation membrane. Unlike when it is attached or deposited on a surface, it is easily peeled off due to the linear velocity of the liquid on the membrane surface, so it does not substantially impede the maintenance of the permeation performance of the separation membrane.
液に添加された吸着性粒子の表面が吸着した有機物に被
覆されることによりその吸着作用が著しく低下するよう
な場合には、適時その粒子を系外に排出し、新たな吸着
性粒子を補充する操作を間けつ的または連続的に行えば
よい。対象とするりアクタが、微生物国体培養型である
場合には、粒子表面の有機物を菌体の栄養源として菌体
に摂取させることにより粒子の吸着作用を回復させれば
、吸着性粒子の入れ替え・補充を行うことなく、長期に
亘って所要の膜面洗浄効果を維持することができる。If the surface of adsorbent particles added to the liquid is coated with adsorbed organic matter and the adsorption effect is significantly reduced, the particles should be expelled from the system in a timely manner and new adsorbent particles should be replenished. This operation may be performed intermittently or continuously. If the target riacter is a cultured type of microorganism, if the adsorption effect of the particles is restored by allowing the bacteria to ingest the organic matter on the surface of the particles as a nutrient source for the bacteria, the adsorptive particles can be replaced. - The required membrane surface cleaning effect can be maintained over a long period of time without replenishment.
乳酸菌連続培養膜量バイオリアクタに、吸着性粒子とし
て活性炭微粉末（粒径：１〜３ｍｍ）とアクリル樹脂微
粉末（粒径：１０〜１５μｍ）とを各々１１０００ｐｐ
リアクタ内に投入して乳酸菌の連続培養（運転時間：
１６８Ｈｒ）を行った。分離膜としては、平均孔径０．
１μｍのアルミナセラミック焼成膜を使用した。また、
比較例として、吸着性粒子の使用を省略した点を除いて
上記と同一条件の従来法による乳酸菌の連続培養を行い
、分離膜の透過性能につき、それぞれ次の結果を得た。11,000 pp each of activated carbon fine powder (particle size: 1 to 3 mm) and acrylic resin fine powder (particle size: 10 to 15 μm) were added as adsorbent particles to a lactic acid bacteria continuous culture membrane bioreactor.
Continuous culture of lactic acid bacteria by introducing into the reactor (operating time:
168 hours). As a separation membrane, the average pore size is 0.
A 1 μm alumina ceramic fired membrane was used. Also,
As a comparative example, lactic acid bacteria were continuously cultured by the conventional method under the same conditions as above except that the use of adsorbent particles was omitted, and the following results were obtained regarding the permeation performance of the separation membrane.
膜面洗浄（逆洗浄） 透過流東
発明例 なし １．１ボ／ボｄａｙ従来
例 １回／ ２４Ｈｒ ０．５ ｒＩｆ／
％ｄａｙすなわち、吸着性粒子を使用しない従来法では
、２４時間周期の逆洗浄処理の反復実施を必要とし、し
かもその透過流束は０．５ｒｒｆ／ｒｙｆｄａｙである
のに対し、発明例では、膜面の洗浄処理を施すことなく
、１、１ ｒｒｆ ／ ｒｒｆｄａｙと、従来法の２倍
以上の高透過性能が維持された。Membrane surface cleaning (backwashing) Permeate flow east invention example None 1.1bo/boday conventional example 1 time/24Hr 0.5 rIf/
In other words, in the conventional method that does not use adsorbent particles, it is necessary to repeatedly carry out backwashing treatment in 24-hour cycles, and the permeation flux is 0.5rrf/ryfday. High permeation performance of 1.1 rrf/rrfday, which is more than twice that of the conventional method, was maintained without performing surface cleaning treatment.
本発明方法は、バイオリアクタに添加した吸着性粒子の
吸着作用により分離膜表面の付着有機物を離脱除去する
こととしたので、従来のように膜面洗浄操作を頻繁に行
う必要がなく、長期に亘る安定した連続稼動が可能とな
り、システム効率が大きく高められる。In the method of the present invention, organic matter adhering to the surface of the separation membrane is separated and removed by the adsorption action of adsorbent particles added to the bioreactor, so there is no need to perform membrane surface cleaning operations as frequently as in the past, and it can be used for a long period of time. This enables stable continuous operation over a long period of time, greatly increasing system efficiency.
Claims (1)
濁させ、分離膜表面の付着物を該吸着性粒子の吸着力に
より分離膜面より離脱除去することを特徴とする膜分離
処理方法。1. A membrane separation process characterized by dispersing and suspending adsorbent particles in a liquid in a membrane bioreactor, and removing deposits on the separation membrane surface from the separation membrane surface by the adsorption power of the adsorbent particles. Method.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11208488A JPH01284304A (en) | 1988-05-09 | 1988-05-09 | Separation treatment with membrane |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11208488A JPH01284304A (en) | 1988-05-09 | 1988-05-09 | Separation treatment with membrane |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH01284304A true JPH01284304A (en) | 1989-11-15 |
Family
ID=14577687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11208488A Pending JPH01284304A (en) | 1988-05-09 | 1988-05-09 | Separation treatment with membrane |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH01284304A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05154470A (en) * | 1991-12-04 | 1993-06-22 | Ebara Infilco Co Ltd | Membrane filter |
| WO2012146815A1 (en) | 2011-04-26 | 2012-11-01 | Universidade De Santiago De Compostela | Method for eliminating pharmaceutical products from waste water |
-
1988
- 1988-05-09 JP JP11208488A patent/JPH01284304A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05154470A (en) * | 1991-12-04 | 1993-06-22 | Ebara Infilco Co Ltd | Membrane filter |
| WO2012146815A1 (en) | 2011-04-26 | 2012-11-01 | Universidade De Santiago De Compostela | Method for eliminating pharmaceutical products from waste water |
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