JPH01272503A - Detergent for sterilization and disinfection of finger - Google Patents

Abstract

PURPOSE:To obtain the subject detergent having excellent sterilizing power and washing power and readily usable, containing respectively specific amounts of anionic, nonionic and/or ampholytic surfactant, ethanol and/or isopropanol and sterilizer as necessary components. CONSTITUTION:(A) A mixture of anionic, nonionic and/or ampholytic surfactant, preferably anionic : nonionic and/or ampholytic surfactant (wt. ratio)=1:0.05-10, especially 1:0.1-2 (B) ethanol and/or isopropanol, (C) sterilizer and (D) water are mixed in the ratio of A=3-30wt.%, B=40-96.9wt.%, preferably 40-92wt.%, especially 60-80wt.%, C=0.1-10wt.% and D=0-56.9wt.%. Washing and sterilization of fingers are simultaneously performed in a simple treatment process and also lathering is stable with a slight remained odor, feeling of use and rinsability are also excellent using the detergent for sterilization and disinfection of finger.

Description

[Detailed description of the invention] [Industrial application field] The present invention relates to a cleaning agent for disinfecting and disinfecting hands.

In particular, the present invention provides a cleaning agent for hand sterilization and disinfection that contains a sterilization disinfectant in a single liquid agent and can effectively clean and disinfect hands with a simple hand washing process.

[Conventional technology and issues]

Employees in food-related industries such as meat and seafood processing and restaurant kitchens; doctors and nurses at hospitals and public health centers;
Conventionally, various methods have been used to wash and sterilize the hands of caregivers, patients, etc. The most common method is to first wash your hands thoroughly with soap, etc., and then go through some kind of sterilization process. Examples of this sterilization method include soaking your hands in disinfectant or spraying them. .

These methods can be said to be effective methods if they are carried out faithfully according to the cleaning and sterilization manuals.

However, since the processing procedure is divided into two steps: cleaning and sterilizing the hands, it is laborious and time-consuming, and the operation tends to be uncertain.Moreover, if either cleaning or sterilization is performed incompletely, It has drawbacks such as extremely reduced efficacy.

Therefore, it cannot necessarily be said to be an effective method under actual usage conditions.

In addition, attempts are currently being made to simultaneously clean and disinfect by adding lid-killing agents to soap or other surfactants, but these methods are still insufficient in terms of their disinfecting power. there were.

Therefore, the purpose of the present invention is to have excellent sterilizing power and cleaning power,
Moreover, it is an object of the present invention to obtain a cleaning agent for hand sterilization and disinfection that is easy to use and can easily obtain a sterilizing effect and a cleaning effect.

[Means to solve the problem]

The inventors of the present invention have completed the present invention as a result of intensive research into a cleaning agent for hand sterilization and disinfection that is highly effective in removing dirt from hands and fingers, has strong sterilizing power, and is easy to use. be.

That is, the invention of the hand sterilizing and disinfecting detergent of the present invention is based on one or more surfactants selected from anionic surfactants, nonionic surfactants, and amphoteric surfactants.
A cleaning agent for hand disinfection containing 40-96.9% by weight of ethanol and/or isopropanol, 0.1-10% by weight of a disinfectant, and 0-56.9% by weight of water. Not only can sterilization be easily carried out in a single treatment, but it also has excellent sterilization and cleaning effects.

The present invention will be explained in more detail below.

Among surfactants, anionic surfactants include soaps, alkyl sulfate ester salts, polyoxyalkylene alkyl ether sulfate ester salts such as polyoxyethylene and polyoxypropylene, α-olefin sulfonates, acyl glutamates, monomers, etc. Alkyl phosphates and the like are preferred, and among these, soaps are particularly preferred from the viewpoint of feeling on use and lathering, and the constituent fatty acids are saturated fatty acids and/or unsaturated fatty acids having 12 to 18 carbon atoms, potassium salts thereof, Ammonium salt, ethanolamine salt, isopropanolamine salt,
Preferred in terms of low irritation to the skin, solubility, etc.
As nonionic surfactants, fatty acid alkylolamides, alkylpolyoxyalkylene ethers such as alkylpolyoxyethylene and alkylpolyoxypropylene, amine oxides, etc. can be used, and as amphoteric surfactants, betaine type, Ampholytic surfactants such as imidacillin type, alanine type, and glycine type are preferred from the viewpoint of stable foaming and alleviation of skin irritation.

These anionic, nonionic, amphoteric surfactants, etc. may be blended alone or in combination of two or more to obtain more preferable performance, but preferably, anionic surfactants, etc. It is preferable to use a nonionic and/or amphoteric surfactant in combination with the agent and a nonionic and/or amphoteric surfactant in terms of foaming and feeling on use.

In this case, anionic surfactant: nonionic and/or amphoteric surfactant = 1:0.05-10 (weight ratio), preferably,
The ratio is 1:0.1 to 2 (weight ratio).

The formulation of the hand sterilizing and disinfecting detergent of the present invention is as described above, but if the surfactant is 3 parts by weight or less, dirt adhering to the hands will not be removed sufficiently, there will be little foaming, and there will be a feeling of use. becomes worse.

If it is more than 30 parts by weight, the irritation to the skin becomes strong, which is undesirable, and there is no improvement in cleansing properties, so it is economically meaningless.

Ethanol and/or isopropanol is blended in an amount of 40 to 96.9% by weight, preferably 40 to 92% by weight, and more preferably 60 to 80% by weight, based on the total amount of the hand disinfectant disinfectant of the present invention.

If the ethanol and/or isopropanol concentration is outside the above range, the bactericidal effect will be reduced.

The disinfectant is not particularly limited as long as it can be used for hand disinfection, and examples include triclosan, trichlorocarbanilide, orthobenzylparachlorophenol, halocarpane, isopropylmethylphenol, chlorhexidine, benzalkonium chloride, benzethonium chloride, Undecylenic acid monoethanolamide, alkyl polyaminoglycine hydrochloride, polyhexamethylene biguanidine hydrochloride, etc. are used, and these may be used alone or in combination of two or more, and all are commercially available.

The blending amount of these fungicides varies depending on their effective concentration, safety, etc., but is generally 0.1 to 10 parts by weight. If the amount is less than 0.1 part by weight, the bactericidal power is insufficient;
Above parts by weight, there is no improvement in bactericidal activity and it is meaningless.
It is also unfavorable from the point of view of safety.

The hand sterilizing and disinfecting detergent of the present invention further contains lanolin, reduced lanolin, sodium pyrrolidone carboxylate, pebutide, acylated bebutide, etc. as a supergreasing agent and a moisturizing agent, as well as pigments and fragrances. etc. can be added as necessary.

When the hand disinfectant disinfectant of the present invention is used, the concentration of ethanol and/or isopropanol in the hand disinfectant disinfectant of the present invention is 40 to 92, preferably 60.
-80% by weight is preferred from the viewpoint of sterilizing cleaning effect, especially sterilizing effect. For example, when the ethanol and/or isopropanol concentration is 40 to 92% by weight, the hand sterilizing and disinfecting cleaner of the present invention Take approximately 3 to 5 g of the agent directly on your hands, rub it well into your hands, and when the ethanol and/or isopropanol evaporates, add a small amount of water and rub thoroughly to obtain a -layer effect.

In addition, when the ethanol and/or isopropanol concentration is 92% by weight or more, the hand sterilizing disinfectant of the present invention is diluted with water at the time of use, and the ethanol and/or isopropanol concentration is 40 to 92% by weight. Preferably, the operation is repeated.

[For production]

Since the hand sterilization disinfectant of the present invention has the above-mentioned structure, it can simultaneously clean and sterilize hands with simple processing operations, and has stable foaming, low residual odor, and good feeling of use. is also good.

〔Example〕

(Preparation of hand sterilizing and disinfecting cleaners) Hand sterilizing and disinfecting cleaners of various compositions were prepared according to the formulations shown in Table 1 below.

The trade names of the main chemicals used and the available light were as follows.

Polyoxyethylene alkyl ether sulfate9. ADEKAHOBE DES-3025 (Jiryu Kakogyo) Coconut oil Jetanolamide・Adekasol CO^ (Jiryuka Kogyo) Nonylphenol ethoxylate・Adekatol MP-700 (Jiryuka Kogyo) Benzalkonium chloride・Cachinal CB- 50 (Toho Chemical) Alkyldiaminoglycine hydrochloride... TEGO51 (GOLD SCHMIDT) (Evaluation of sterilizing power) Measurement of sterilizing power, feeling of use, and foaming of various hand sterilizing and disinfecting detergents prepared with the formulations in Table 1. , a test was conducted on the remaining tools after cleaning. To measure the bactericidal power, we adopted the wiping method as the test method most suited to actual usage conditions. That is, first, a person different from the test subject (hereinafter referred to as the tester) wipes the palm of one of the test subjects (including between the fingers and fingernails) with sterile gauze moistened with physiological saline for 1 to 2 minutes. 1. Next, the tester took each hand sterilization disinfectant (Example products No. 1 to No. 5 and Comparative example products No. 1 to No. 5) 51F, and
The test subject uses both hands to spread the cleansing agent over the entirety of their fingers, then apply water to create a lather and cleanse. After rinsing thoroughly under running water, the tester similarly wipes the other hand of the subject's hand than the one that was wiped before washing.

Each gauze that has been wiped off is added to sterile physiological saline and shaken well, and this is used as a bacterial solution to measure the number of bacteria after culturing at 37°C for 48 hours using the pour plate method. Comparing the number of bacteria on the hands and fingers before and after washing,
The sterilization rate was calculated and used as an index of the sterilization power of each hand sterilization disinfectant. The evaluation test was conducted with 10 subjects.

The results are shown in Table-2.

From Table 2 above, it can be seen that when the disinfectant is at the same concentration, the bactericidal power improves as the amount of ethanol increases (
Example 1, Comparative Examples 1 and 2).

Comparative Examples 1 and 4) containing no ethanol, those containing only 30% by weight of ethanol (Comparative Example 2), and Comparative Example 5) containing no disinfectant do not show much bactericidal effect. .

Furthermore, Comparative Example 3), which had a low surfactant concentration, had poor detergency, foaming, and usability, and also had low sterilizing power because the sterilizing effect of the surfactant was impaired.

〔Effect of the invention〕

The cleaning agent for hand sterilization and disinfection of the present invention has excellent sterilization and cleaning power, and can simultaneously wash and sterilize hands with simple processing operations.Moreover, it foams stably, leaves little residual material, and can be easily cleaned. It is also excellent in feeling when used and ease of rinsing.

Claims (1)

[Claims] One or more surfactants selected from anionic surfactants, nonionic surfactants, and amphoteric surfactants 3~
30% by weight, 40-96.9% by weight of ethanol and/or isopropanol, and 0.1-10% by weight of disinfectant.
and a cleaning agent for hand disinfection containing 0 to 56.9% by weight of water.