JPH01230360A - Medical bag - Google Patents

Abstract

PURPOSE:To reduce blocking between respective sheets by forming more than two kinds of projections which are different in form and/or height on the inner and/or outer surfaces of at least one of the sheets forming a medical bag. CONSTITUTION:A blood bag 1 is composed of a master bag 2 containing collected blood and of No.1 and No.2 slave bags 3 and 4 for containing blood contained in the master bag 2. Projections 16 and 17 which are different in form and in height are formed on the inner surface of a sheet 15 constituting the master bag 2 and the slave bags 3 and 4. The projection 16 is formed into a cube with the height of (h) and the width of (w), and the projection 17 is formed into a semi-sphere with the height of H and the width of W. As for the relation among the heights H and (h) and the widths W and (w) of the respective projections 16 and 17, H is larger than (h) and W is larger than (w). When recesses and projections per unit area in the sheet surface are increased in number, air in the medical bag or air in spaces among more than two medical bags is thereby highly dispersed, blocking between the inner surfaces of the medical bag or between the outer surfaces of the medical bags can be prevented. In addition, change in the location of these projections enables partial blocking from being effectively prevented.

Description

Detailed Description of the Invention [Industrial Application Field] The present invention relates to a blood bag, a plasma pool bag, and/or an infusion bag containing a drug solution, which are used to store blood components and separate them. Regarding the improvement of medical bags such as

(1 line margin) [Prior art] Medical bags such as blood bags currently in use are:
It is made of soft polyolefin resin such as polyvinyl chloride or polyethylene, and when shipped as a product, it is subjected to high-pressure steam sterilization and then folded or layered in aluminum foil, plastic containers, etc., and shipped. ing.

However, due to the thermal history during high-pressure steam sterilization and the physical pressure during packaging, the inner surfaces or outer surfaces of the sheets that make up the medical bag (for example, in the case of blood bags, parent bags and child bags) may come into close contact with each other. It has the disadvantage that it is easily blocked (hereinafter referred to as "blocking").

Therefore, in order to reduce or eliminate such blocking, irregularities are formed by embossing on both or one of the inner surfaces of these sheets.

For example, as shown in FIG. 10, there is one in which gentle undulations 31 are formed irregularly, or as shown in FIG. 11, projections 32 of the same shape are formed regularly at regular intervals.

However, these uneven shapes do not necessarily provide a sufficient effect to eliminate blocking.

Furthermore, in recent years, when blood components are fractionated in a blood bag consisting of a parent bag and a child bag, the blood is usually collected into the parent bag and then filled into a centrifugal bucket together with the child bag to apply centrifugal force. Because blood moves to the bottom of the bag and the bottom of the parent bag is pushed by the pressure of the blood, it was confirmed that blocking was likely to occur near the bottom of the parent bag and child bag. ing.

It takes a considerable amount of force to separate the blocked parent bag and child bag in this way, and if you apply more force than necessary, the interface between the blood components in the parent bag that has been separated will be disturbed and the blood components will have to be centrifuged again. A problem arose in that the process had to be redone.

[Means for Solving the Problems] In order to solve the above problems, the inventors of the present invention have made extensive studies and have arrived at the following invention.

That is, the present invention provides a medical bag in which two or more types of protrusions with different shapes and/or heights are formed on the inner and/or outer surfaces of at least one sheet constituting the medical bag. be.

[Effects] The above configuration substantially increases the unevenness per unit area of the sheet surface and improves the dispersion of air existing in the medical bag or between two or more medical bags, making it suitable for medical use. Blocking between the inner surface of the bang or the outer surface of the medical bag can be suppressed. Further, by changing the arrangement of these protrusions, a partial blocking prevention effect can be obtained.

[Example] The case of a blood bag will be described below. Figure 1 1-
1', shows a schematic diagram of the blood bag 1.

The blood bag 1 includes a parent bag 2 for storing collected blood and a first reservoir for storing the blood stored in the parent bag 2.
, second child bag 3.4.

Parent bag 2 includes CPD, ACD-A, ACD-B.
A blood preservation solution such as a solution is enclosed.

The parent bag 2 includes a connecting tube 1 in which a blood collection needle 5, a blood collection tube 6, a blood transfusion lower, a protector 8, and a communication piece 9 are attached for piercing the donor's blood vessel and introducing blood.
Consists of 0.

The parent bag 2 and child bag 3.4 are connected to the communication tube 11.1.
2.13 and a branch pipe 14.

FIG. 2 shows an enlarged view of the sheet 15 constituting the parent bag 2 and child bag 3 of FIG.

On the inner surface of the sheet 15, projections 16 and 17 having mutually different shapes and heights are formed.

The protrusion 16 is cubic and has a height h and a width W.
is hemispherical and has a height H1 and a width W.

The relationship between the heights H, h and widths W, W of the protrusions 16 and 17 is H
>h, W>w.

In FIG. 3, protrusions 16a and 17a having different shapes and heights are formed on the inner and outer surfaces of the seal l-15a.

FIG. 4 shows the same shape on the inner surface of the sheet 15b, 7J',
In addition, protrusions 16b and 17b having different heights H and h are formed.

In Fig. 5, protrusions 16c and 17c of different shapes and heights are formed on the inner surface of one sheet t-15c, and uniform protrusions 170' are formed on the inner surface of the other sheet t-15c. It is.

The specific shapes of the protrusions formed on the inner and/or outer surfaces of the sheet constituting the blood bun of the present invention include, in addition to the cubic and hemispherical shapes described above, rectangular parallelepipeds, right prisms, tilted prisms, right-angled mirrors, and right circular prisms. , a right circular truncated cone, a spherical zone, or an irregular shape.
It can be formed by combining different types.

In addition, when forming three or more types of protrusions, the height of the protrusions is
It is sufficient that at least two protrusions have different heights.

Further, the following embodiment can be considered as an embodiment in which two or more types of projections are arranged on the sheet surface -h.

(1) As shown in FIG. 6, two or more types of protrusions are arranged at specific positions without being mixed.

(2) As shown in FIG. 7, two or more types of protrusions are formed in positions where sheet blocking is likely to occur, and one type of protrusions are formed in other parts.

(3) As shown in FIG. 8, a mode in which protrusions constituting two or more types of protrusions are formed in a mixed manner over the entire surface of the sheet (excluding the fused portion of the sheet).

(4) In the above (]) to (3), the respective protrusions constituting two or more types of protrusions are formed regularly or irregularly.

(5) As shown in FIG. 9, in (2) to (3) above,
An embodiment in which two or more types of protrusions are formed regularly or irregularly for each two or more types of blocks.

(6) In the above (1) to (5), an aspect in which two or more types of protrusions are formed on the inner surface and/or outer surface of at least one sheet.

The maximum height 11 of the two types of protrusions on the north side is preferably 200 squares or less, and if it is 200 μ1 or more, it tends to impede the appearance and transparency of the blood bag and cause damage to blood components.

On the other hand, the minimum height h is preferably 5 cm or more. If the amount is less than 5, the effect of preventing blocking is not sufficient.

The maximum width W is preferably 500 degrees or less, and if it is greater than 500 degrees, the contact area between the protrusions becomes large and blocking is likely to occur.

The minimum width W is preferably 20 squares or more. If it is less than 20g, the effect on blocking will decrease and processing will be difficult.

Blood band of the present invention as described above (Example 1, Example 2)
) and conventional blood bags (Comparative Example 1, Comparative Example 2) were tested and compared for their anti-blocking effects.

Here, Example 1 refers to the shape of the protrusions shown in FIG. 2 (protrusions 16, 17) and the arrangement shown in FIG. 8 (protrusions 16f, 17).
A blood bag consisting of a pair of sheets formed in f).

In Example 2, the protrusions are shaped as shown in FIG. 3 (protrusions 16a,
17a) and the arrangement shown in FIG. 7 (protrusions 16e, 17e)
A blood bag consisting of a pair of sheets formed into

Comparative Example 1 is a liquid-retaining bag made of a pair of sheets in which projections are formed in an irregular shape and arrangement (projections 31) as shown in FIG.

Comparative Example 2 is a blood bag in which protrusions are formed in a regular shape and arrangement as shown in FIG.

After high-pressure steam sterilization of Example 1, Comparative Example 1, and Comparative Example 2 at I21'C in an autoclave for 20 minutes, a tensile test was conducted to compare the peel strength of both sheets. Example 1>Comparative Example 1>Comparison In the order of Example 2, it was easy to peel off.

Further, when Example 2 was used for fractionating blood components, no blocking was observed between the bottoms of the parent bag and child bag after centrifugation.

[Effects of the Invention] As described above, in the present invention, two or more types of protrusions with different shapes and/or heights are provided on the inner surface of the sheet and/or at least one
Or, by forming it on the outer surface, the contact area between the sheets is reduced, and the surface area of the unevenness on the sheet surface is increased, making it easier to diffuse the air inside the panda into the bag, reducing blocking between the sheets. can be done.

■By arranging the protrusions of the present invention in locations where blocking is likely to occur, blocking can be reliably prevented.

This invention has excellent effects as a shade.

[Brief explanation of the drawing]

Figure 1 is a schematic diagram of the blood bag, Figures 2 to 5 are the schematic diagram of the blood bag.
FIGS. 6 to 9 are partially enlarged views of the sheet constituting the blood bag shown in FIG. , Fig. 11 is an enlarged view of the C I part of the conventional NU fluid bung.
5 is a blood collection needle, 6d is a blood collection duplex, 7 is a blood transfusion 1-1.
8 is a protector, 9 is a communication piece, 10 is a connecting tube, 11, 12, 13 is a connecting tube, 14 is a branch pipe,
15 and 15a-15g are sheets, 16.16a-16
g, 17.17a-17g show protrusions. Patent applicant: Kawasumi Chemical Industry Co., Ltd.

Claims (1)

[Claims] In a medical bag such as a blood bag used to store blood components and separate them, a plasma pool bag, and/or an infusion bag formed by enclosing a medical solution, the inner surface of at least one sheet constituting the medical bag. and/or a medical bag characterized in that two or more types of protrusions with different shapes and/or heights are formed on the outer surface.