JPH0111291Y2 - - Google Patents

Description

[Detailed Description of the Invention] The present invention relates to a liquid reaction container shaking device used in chemical reactions.

Generally, when carrying out a chemical reaction of liquid agents, a shaking device is used to forcibly mix and stir the reaction liquid in order to promote the reaction. As a conventional shaking device of this type, one is known in which the bottom of a test tube, flask, etc. is held and eccentrically rotated.

However, all of these conventional shaking devices are designed to perform only the shaking operation separately, and are not used for a series of operations such as injection of various liquids and separation of necessary parts after reaction. It was something to do.

On the other hand, automation has been desired in recent years in chemical analysis work, and one method of automation is to support the reaction container on a turntable, and rotate the turntable to move the reaction container to various processing positions and automatically perform various treatments. Methods are being developed to do so.

In view of the current situation, the present invention is designed to automatically perform various operations in a reaction vessel supported by a turntable, such as chemical analysis or other reaction processing, while the reaction vessel is supported on a turntable. The purpose of this device is to provide a shaking device for liquid reaction containers that can perform shaking operations, and its gist is that a pair of reaction containers are placed facing each other in a vertically penetrating window formed on the periphery of a turntable. A support pin is provided protrudingly, and an engagement groove into which the pin is loosely inserted is provided in a built-up portion formed on the outer circumferential surface of the upper end of the reaction vessel having a bottomed cylindrical shape, and the pin is inserted into the engagement groove. The reaction container is suspended and supported by a turntable, and a crank is attached to the lower side of the turntable in correspondence with one of the reaction containers and is fixed to a vertical shaft that is rotatably driven, and is rotatable by a crank pin of the crank. A vibration excitation mechanism is provided with a vibrator that is attached to the oscillator and comes into contact with the bottom of the vibrated container, and is movable up and down by an elevator, and an upper end holder that elastically presses and supports the upper end of the reaction container is provided on the upper side of the vibration excitation mechanism. is movable up and down by an elevating mechanism, the turntable is stopped at a desired position, both elevating mechanisms are operated to raise the vibration generating mechanism, and the upper end holder is lowered to press and support the upper and lower sides of the reaction vessel. The present invention relates to a shaking device for a liquid reaction container, which rotates a crank under the condition.

Next, an example of an apparatus for carrying out the present invention will be described with reference to the drawings.

In the figure, 1 is a turntable provided within the main body of the apparatus. This turntable 1 is supported with a motor 3 around a shaft 2 so as to be rotatable at high speed, and
A disc 4 for angle detection is fixed to the shaft 2, and a sensor 4a detects the through hole of the disc 4, and controls the drive of the motor 3 so that the required angle of rotation and stop is achieved. I have to.

Reaction container support parts 5, 5, . . . are provided at regular intervals on the periphery of the turntable 1. As shown in FIGS. 2 and 3, this reaction vessel support part 5 has a concave part 6 which is made by recessing the periphery of the turntable 1 in the radial direction. A container support ring 8 is rotatably supported by a pair of pins 7, 7 facing toward each other, and the tips of the pins 7, 7 protrude from the inner peripheral surface of the container support ring 8. The reaction vessel 9 is supported within the vessel support ring 8, and a bayonet groove 10 is formed on the outer circumferential surface of the upper end of the reaction vessel 9, and a pin 7 is fitted into this groove 10 and rotated. The bayonet groove 10 is designed to be prevented from coming off by the L-shaped innermost vertical part 1.
0a is formed, and the pin 7 and reaction vessel 9 are
can move up and down relatively.

Above the turntable that supported the reaction container 9 in this manner, supporting substrates 13 and 14 were provided which were movable up and down with lifting means 11 and 12, and the supporting substrates 13 and 14 were connected to the pump. Various suction/exhaust nozzles 15 are arranged, and a support substrate 17 is provided below the turntable 1 and is moved up and down by a lifting means 16, and constant temperature layers 18, 18, . . . are provided on the support substrate 17. It is being Then, the turntable 1 automatically rotates according to a preset program and stops at various processing positions, and the nozzle 15 is raised and lowered to suck and discharge the reaction liquid, so that automatic reaction processing is performed. ing.

A vibration generating mechanism 20 is provided at a stop position of a reaction container 9 supported by the turntable 1 and containing various reaction reagents and the like. As shown in FIG. 5, this vibration generating mechanism 20 has a support cylinder 21 fixed to the above-mentioned support substrate 17, and a spring 22 is interposed in this support cylinder 21 so that a motor 23 is biased in the projecting direction. It is accommodated. This motor 23
A detent fitting 24 is fixed to the support cylinder 21, and its lower end is inserted into a detent insertion hole 25 of the support tube 21.
A crank 26 is fixed to the shaft 23a of the motor 23, and a vibrator 27 is rotatably supported at a crank pin position of the crank 26 via a bearing. This vibrator 27 has an arm 27a for preventing rotation.
is provided protrudingly, and an elongated hole 28 is opened in the arm 27a, into which the upper end of the above-mentioned rotation stopper 24 is inserted, so that only that position can be rotated relative to the motor.

On the other hand, a presser 29 is provided on the support substrate 14 above the turntable 1 and descends onto the turntable 1 to press the upper end opening of the reaction container 9. This presser 29 is configured to press the upper end opening of the reaction vessel 9 with a tapered surface 20a at its lower end, and is attached to the support substrate 15 via an elastic member 30 made of anti-vibration rubber.

The shaking operation by the vibrating mechanism 20 configured in this way is performed by raising the support substrate 17 and
is brought into contact with the lower end of the reaction vessel 9, and the support substrate 15 is lowered to press the upper end with the presser 29. At this time, the reaction vessel 9 is slightly raised so that the pin 7 supporting it is located in the middle of the vertical portion of the bayonet groove 10, and the vibrator 27
and the presser 29.

In this state, the motor 23 is rotated at high speed to rotate the vibrator 27 and shake the reaction container 9.

The liquid reaction container shaking device of the present invention is constructed as described above, and the reaction container is supported by the turntable with a support pin, and the support is achieved by loosely fitting the support pin into the engagement groove of the reaction container. The reaction container is supported by the turntable by suspending it, lowering the presser from above the turntable, raising the vibrator at the same time, and shaking it by holding it between the presser and the vibrator. Therefore, the shaking process is incorporated into the automatic reaction processing process in which the reaction vessel is supported on a turntable and sequentially rotated, and various operations are sequentially performed while the position is determined. It has become easier.

[Brief explanation of the drawing]

The drawings show an example of the implementation of the present invention, and FIG. 1 is a vertical cross-sectional view schematically showing the entire reaction treatment apparatus, and FIG.
3 is a plan view of the turntable, FIG. 3 is an enlarged sectional view of the reaction vessel support, FIG. 4 is a partial side view of the reaction vessel, and FIG. 5 is an enlarged sectional view of the shaking device. DESCRIPTION OF SYMBOLS 1... Turntable, 5... Reaction container support part, 7... Pin, 9... Reaction container, 10... Groove,
20... Vibration mechanism, 23... Motor, 26...
Crank, 27... vibrator, 29... presser.

Claims (1)

[Scope of utility model registration request] A pair of reaction vessel support pins are protruded from and opposite to each other within a vertically penetrating window formed on the periphery of the turntable, and a built-up portion is formed on the outer circumferential surface of the upper end of the reaction vessel having a cylindrical shape with a bottom. An engagement groove into which the pin is loosely inserted is provided, and the pin is inserted into the engagement groove to suspend and support the reaction container on the turntable, and the reaction container is made to correspond to one of the reaction containers on the turntable. At the bottom, there is a vibration mechanism consisting of a crank fixed to a rotating vertical shaft and a vibrator that is rotatably attached to the crank pin of the crank and comes into contact with the bottom of the vibrating container, which can be moved up and down by an elevator. and an upper end holder for elastically pressing and supporting the upper end of the reaction container is provided on the upper side thereof so as to be movable up and down by a lifting mechanism,
The turntable is stopped at a desired position, and both lifting and lowering mechanisms are operated to raise the vibration generating mechanism, and the upper end holder is lowered to press and support the top and bottom of the reaction vessel, and the crank is driven to rotate. Liquid reaction container shaking device.