JP7822953B2 - 急性骨髄性白血病(aml)に対する新規の腫瘍特異的抗原及びそれらの使用 - Google Patents

急性骨髄性白血病(aml)に対する新規の腫瘍特異的抗原及びそれらの使用

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JP7822953B2
JP7822953B2 JP2022562561A JP2022562561A JP7822953B2 JP 7822953 B2 JP7822953 B2 JP 7822953B2 JP 2022562561 A JP2022562561 A JP 2022562561A JP 2022562561 A JP2022562561 A JP 2022562561A JP 7822953 B2 JP7822953 B2 JP 7822953B2
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hla
aml
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JP2023521219A (ja
JP2023521219A5 (cg-RX-API-DMAC7.html
Inventor
ペロー クラウデ
ティボー ピエール
ルミュー セバスティアン
エークス グレゴリー
ハーディ マリー-ピエール
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Universite de Montreal
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70539MHC-molecules, e.g. HLA-molecules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2022562561A 2020-04-14 2021-03-15 急性骨髄性白血病(aml)に対する新規の腫瘍特異的抗原及びそれらの使用 Active JP7822953B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025153952A JP2026009916A (ja) 2020-04-14 2025-09-17 急性骨髄性白血病(aml)に対する新規の腫瘍特異的抗原及びそれらの使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063009853P 2020-04-14 2020-04-14
US63/009,853 2020-04-14
PCT/CA2021/050340 WO2021207823A1 (en) 2020-04-14 2021-03-15 Novel tumor-specific antigens for acute myeloid leukemia (aml) and uses thereof

Related Child Applications (1)

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JP2025153952A Division JP2026009916A (ja) 2020-04-14 2025-09-17 急性骨髄性白血病(aml)に対する新規の腫瘍特異的抗原及びそれらの使用

Publications (3)

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JP2023521219A JP2023521219A (ja) 2023-05-23
JP2023521219A5 JP2023521219A5 (cg-RX-API-DMAC7.html) 2024-02-29
JP7822953B2 true JP7822953B2 (ja) 2026-03-03

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JP2022562561A Active JP7822953B2 (ja) 2020-04-14 2021-03-15 急性骨髄性白血病(aml)に対する新規の腫瘍特異的抗原及びそれらの使用
JP2025153952A Pending JP2026009916A (ja) 2020-04-14 2025-09-17 急性骨髄性白血病(aml)に対する新規の腫瘍特異的抗原及びそれらの使用

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US (1) US20230287070A1 (cg-RX-API-DMAC7.html)
EP (1) EP4136099A4 (cg-RX-API-DMAC7.html)
JP (2) JP7822953B2 (cg-RX-API-DMAC7.html)
KR (1) KR20220167288A (cg-RX-API-DMAC7.html)
CN (1) CN115397842A (cg-RX-API-DMAC7.html)
AU (1) AU2021256477A1 (cg-RX-API-DMAC7.html)
BR (1) BR112022020376A2 (cg-RX-API-DMAC7.html)
CA (1) CA3173666A1 (cg-RX-API-DMAC7.html)
IL (1) IL296881A (cg-RX-API-DMAC7.html)
MX (1) MX2022012758A (cg-RX-API-DMAC7.html)
WO (1) WO2021207823A1 (cg-RX-API-DMAC7.html)

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Publication number Priority date Publication date Assignee Title
CN114045341B (zh) * 2021-11-30 2024-03-01 中南大学 口腔黏膜下纤维化恶性进展或其所致口腔癌的早期诊断和/或预后生物标志物的应用及产品
WO2024077376A1 (en) * 2022-10-11 2024-04-18 Université de Montréal Novel tumor-specific antigens for myeloid leukemia and uses thereof

Citations (2)

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Publication number Priority date Publication date Assignee Title
JP2017524337A (ja) 2014-05-09 2017-08-31 イマティクス バイオテクノロジーズ ゲーエムベーハー 急性骨髄性白血病(aml)などの血液のいくつかの腫瘍に対する新規免疫療法
JP2018520670A (ja) 2015-06-24 2018-08-02 アイム・セラピューティクス・べー・フェー Aml抗原及びその使用

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US6867283B2 (en) * 2001-05-16 2005-03-15 Technion Research & Development Foundation Ltd. Peptides capable of binding to MHC molecules, cells presenting such peptides, and pharmaceutical compositions comprising such peptides and/or cells
ES2532896T5 (es) * 2008-05-14 2018-03-20 Immatics Biotechnologies Gmbh Péptidos del MHC de clase II novedosos y potentes derivados de survivina y neurocan
EP2576614A4 (en) * 2010-05-24 2013-11-13 Phosimmune Inc CLASS I-MHC PHOSPHOPEPTIDES FOR CANCER IMMUNOTHERAPY AND DIAGNOSIS
SG11201507883SA (en) * 2013-03-29 2015-10-29 Sumitomo Dainippon Pharma Co Ltd Wt1-antigen peptide conjugate vaccine
HRP20191671T1 (hr) * 2014-05-09 2019-12-13 Immatics Biotechnologies Gmbh Nova imunoterapija za liječenje nekoliko tumora krvi, kao što je akutna mijeloidna leukemija (aml)
HRP20200967T1 (hr) * 2014-06-20 2020-10-16 Immatics Biotechnologies Gmbh Nova imunoterapija protiv nekoliko tumora krvi, posebice kronične limfoidne leukemije (cll)
GB201411037D0 (en) * 2014-06-20 2014-08-06 Immatics Biotechnologies Gmbh Novel immunotherapy against several tumors of the blood, in particular chronic lymphoid leukemai (CLL)
EP3277841A1 (en) * 2015-03-31 2018-02-07 INSERM (Institut National de la Santé et de la Recherche Médicale) New biomarker for outcome in aml
GB201511546D0 (en) * 2015-07-01 2015-08-12 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
GB201513921D0 (en) * 2015-08-05 2015-09-23 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers
CN109071605A (zh) * 2016-04-06 2018-12-21 伊玛提克斯生物技术有限公司 用于aml和其他癌症免疫治疗的新型肽和肽组合物
TWI796299B (zh) * 2016-08-26 2023-03-21 德商英麥提克生物技術股份有限公司 用於頭頸鱗狀細胞癌和其他癌症免疫治療的新型肽和支架
EA201992416A1 (ru) * 2017-04-10 2020-02-25 Имматикс Байотекнолоджиз Гмбх Пептиды и комбинации пептидов для применения в иммунотерапии лейкозов и других видов рака
US10925947B2 (en) * 2018-06-29 2021-02-23 Immatics Biotechnologies Gmbh A*03 restricted peptides for use in immunotherapy against cancers and related methods
TW202019955A (zh) * 2018-07-31 2020-06-01 德商英麥提克生物技術股份有限公司 B*07 限制肽和肽組合的抗癌免疫治療和相關方法
CN112639136B (zh) * 2018-08-30 2024-08-02 蒙特利尔大学 用于鉴定肿瘤特异性抗原的基于蛋白质基因组学的方法
TW202024121A (zh) * 2018-09-18 2020-07-01 德商英麥提克生物技術股份有限公司 A*01 限制肽和肽組合物在抗癌免疫治療中的用途和相關方法

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JP2017524337A (ja) 2014-05-09 2017-08-31 イマティクス バイオテクノロジーズ ゲーエムベーハー 急性骨髄性白血病(aml)などの血液のいくつかの腫瘍に対する新規免疫療法
JP2018520670A (ja) 2015-06-24 2018-08-02 アイム・セラピューティクス・べー・フェー Aml抗原及びその使用

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Front. Immunol.,2019年,Vol.10, No.2934,pp.1-7
Genome Medicine,2019年,Vol.11, No.29,pp.1-3

Also Published As

Publication number Publication date
EP4136099A4 (en) 2024-08-07
CN115397842A (zh) 2022-11-25
CA3173666A1 (en) 2021-10-21
AU2021256477A1 (en) 2022-11-10
BR112022020376A2 (pt) 2022-11-22
JP2026009916A (ja) 2026-01-21
JP2023521219A (ja) 2023-05-23
US20230287070A1 (en) 2023-09-14
MX2022012758A (es) 2022-11-30
EP4136099A1 (en) 2023-02-22
IL296881A (en) 2022-12-01
WO2021207823A1 (en) 2021-10-21
KR20220167288A (ko) 2022-12-20

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