JP7797199B2 - 子癇前症に特異的な循環ｒｎａシグネチャー - Google Patents

子癇前症に特異的な循環ｒｎａシグネチャー

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JP7797199B2
JP7797199B2 JP2021558675A JP2021558675A JP7797199B2 JP 7797199 B2 JP7797199 B2 JP 7797199B2 JP 2021558675 A JP2021558675 A JP 2021558675A JP 2021558675 A JP2021558675 A JP 2021558675A JP 7797199 B2 JP7797199 B2 JP 7797199B2
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rna
samples
adaboost
genes
eclampsia
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JP2023501760A5 (https=
JP2023501760A (ja
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サラ・イー・シュルツァバーガー
フィオナ・ケイパー
サラ・キニングス
スザンヌ・ローバック
カルロ・ランダイス－ヒンチリフ
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イルミナ インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2021558675A 2019-11-22 2020-11-20 子癇前症に特異的な循環ｒｎａシグネチャー Active JP7797199B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962939324P 2019-11-22 2019-11-22
US62/939,324 2019-11-22
PCT/US2020/061466 WO2021102236A1 (en) 2019-11-22 2020-11-20 Circulating rna signatures specific to preeclampsia

Publications (3)

Publication Number Publication Date
JP2023501760A JP2023501760A (ja) 2023-01-19
JP2023501760A5 JP2023501760A5 (https=) 2023-11-30
JP7797199B2 true JP7797199B2 (ja) 2026-01-13

Family

ID=73835822

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JP2021558675A Active JP7797199B2 (ja) 2019-11-22 2020-11-20 子癇前症に特異的な循環ｒｎａシグネチャー

Country Status (7)

Country Link
US (3) US11753685B2 (https=)
EP (1) EP4010495A1 (https=)
JP (1) JP7797199B2 (https=)
CN (1) CN113677807A (https=)
AU (1) AU2020387423A1 (https=)
CA (1) CA3131748A1 (https=)
WO (1) WO2021102236A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019227015A1 (en) 2018-05-25 2019-11-28 Illumina, Inc. Circulating rna signatures specific to preeclampsia
US11753685B2 (en) 2019-11-22 2023-09-12 Illumina, Inc. Circulating RNA signatures specific to preeclampsia
US20230394492A1 (en) * 2022-06-02 2023-12-07 Noodle Analytics, Inc. Ai-based defect diagnosis system and method
EP4532769A2 (en) 2022-06-03 2025-04-09 Illumina, Inc. Circulating rna biomarkers for preeclampsia
WO2024124587A1 (zh) * 2022-12-16 2024-06-20 深圳华大基因股份有限公司 子痫前期生物标志物及其用途
CN119068988B (zh) * 2024-08-13 2025-04-15 北京国浩宇医疗科技有限公司 一种针对单细胞表达谱的智能化异常检测系统

Citations (4)

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JP2006515517A (ja) 2003-01-17 2006-06-01 ザ チャイニーズ ユニバーシティ オブ ホンコン 妊娠障害診断マーカーとしての血中ｍＲＮＡ
JP2008524993A (ja) 2005-03-18 2008-07-17 ザ チャイニーズ ユニバーシティー オブ ホンコン 出生前診断およびモニタリングのためのマーカー
US20110171650A1 (en) 2008-09-16 2011-07-14 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Gene expression related to preeclampsia
JP2016511641A (ja) 2013-02-28 2016-04-21 ザ チャイニーズ ユニバーシティ オブ ホンコン 超並列ｒｎａ配列決定による母体血漿のトランスクリプトーム解析

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WO1991006678A1 (en) 1989-10-26 1991-05-16 Sri International Dna sequencing
ATE377093T1 (de) 2000-07-07 2007-11-15 Visigen Biotechnologies Inc Sequenzbestimmung in echtzeit
AU2002227156A1 (en) 2000-12-01 2002-06-11 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
US7057026B2 (en) 2001-12-04 2006-06-06 Solexa Limited Labelled nucleotides
WO2004018497A2 (en) 2002-08-23 2004-03-04 Solexa Limited Modified nucleotides for polynucleotide sequencing
DE102004035479A1 (de) 2004-07-14 2006-02-16 Volkswagen Ag Sicherheitssystem für einen Fahrzeugsitz
CA2579150C (en) 2004-09-17 2014-11-25 Pacific Biosciences Of California, Inc. Apparatus and method for analysis of molecules
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CA2648149A1 (en) 2006-03-31 2007-11-01 Solexa, Inc. Systems and devices for sequence by synthesis analysis
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EP2132343B1 (en) 2007-03-01 2012-08-29 Université Catholique de Louvain Method for the determination and the classification of rheumatic conditions
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EP4532769A2 (en) 2022-06-03 2025-04-09 Illumina, Inc. Circulating rna biomarkers for preeclampsia

Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
JP2006515517A (ja) 2003-01-17 2006-06-01 ザ チャイニーズ ユニバーシティ オブ ホンコン 妊娠障害診断マーカーとしての血中ｍＲＮＡ
JP2008524993A (ja) 2005-03-18 2008-07-17 ザ チャイニーズ ユニバーシティー オブ ホンコン 出生前診断およびモニタリングのためのマーカー
US20110171650A1 (en) 2008-09-16 2011-07-14 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Gene expression related to preeclampsia
JP2016511641A (ja) 2013-02-28 2016-04-21 ザ チャイニーズ ユニバーシティ オブ ホンコン 超並列ｒｎａ配列決定による母体血漿のトランスクリプトーム解析

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Also Published As

Publication number Publication date
AU2020387423A1 (en) 2021-09-30
US11753685B2 (en) 2023-09-12
US20250270646A1 (en) 2025-08-28
US20230135486A1 (en) 2023-05-04
JP2023501760A (ja) 2023-01-19
US20210155987A1 (en) 2021-05-27
WO2021102236A1 (en) 2021-05-27
US12359256B2 (en) 2025-07-15
EP4010495A1 (en) 2022-06-15
CN113677807A (zh) 2021-11-19
CA3131748A1 (en) 2021-05-27

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