JP7748877B2 - 複雑な生物学的マトリックスにおける試料間分析物変動性の制御 - Google Patents

複雑な生物学的マトリックスにおける試料間分析物変動性の制御

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Publication number
JP7748877B2
JP7748877B2 JP2021567993A JP2021567993A JP7748877B2 JP 7748877 B2 JP7748877 B2 JP 7748877B2 JP 2021567993 A JP2021567993 A JP 2021567993A JP 2021567993 A JP2021567993 A JP 2021567993A JP 7748877 B2 JP7748877 B2 JP 7748877B2
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dilution
analyte
model
dilution series
level
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JP2022532212A (ja
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トーマス フラハ
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Somalogic Inc
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Somalogic Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/20—Identification of molecular entities, parts thereof or of chemical compositions

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Computing Systems (AREA)
  • Theoretical Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2021567993A 2019-05-17 2020-05-15 複雑な生物学的マトリックスにおける試料間分析物変動性の制御 Active JP7748877B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962849212P 2019-05-17 2019-05-17
US62/849,212 2019-05-17
PCT/US2020/033033 WO2020236544A1 (en) 2019-05-17 2020-05-15 Controlling intersample analyte variability in complex biological matrices

Publications (2)

Publication Number Publication Date
JP2022532212A JP2022532212A (ja) 2022-07-13
JP7748877B2 true JP7748877B2 (ja) 2025-10-03

Family

ID=71016636

Family Applications (1)

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JP2021567993A Active JP7748877B2 (ja) 2019-05-17 2020-05-15 複雑な生物学的マトリックスにおける試料間分析物変動性の制御

Country Status (11)

Country Link
US (1) US12480956B2 (enExample)
EP (1) EP3969900A1 (enExample)
JP (1) JP7748877B2 (enExample)
KR (1) KR20220009948A (enExample)
CN (1) CN113826170B (enExample)
AU (1) AU2020278570A1 (enExample)
BR (1) BR112021022532A8 (enExample)
CA (1) CA3140053A1 (enExample)
IL (1) IL288014A (enExample)
SG (1) SG11202111365QA (enExample)
WO (1) WO2020236544A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220386905A1 (en) * 2021-03-02 2022-12-08 Pacific Diabetes Technologies Inc Signal processing algorithm for improving accuracy of a continuous glucose sensor and a combined continuous glucose sensor and insulin delivery cannula
GB202116626D0 (en) * 2021-11-18 2022-01-05 Fluidic Analytics Ltd Improvements in or relating to a method of analysing a component in a sample
CN117497037B (zh) * 2023-11-17 2024-08-16 上海倍谙基生物科技有限公司 一种基于广义线性模型的培养基组分敏感性分析方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012500401A (ja) 2008-08-21 2012-01-05 バイオ−ラッド ラボラトリーズ，インコーポレイティド 分析物の比を決定する校正表面方法
JP2013528379A (ja) 2010-05-21 2013-07-11 オームクス コーポレーション Ｐｓａ酵素活性アッセイによる癌の検出

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Publication number Priority date Publication date Assignee Title
DE69128350T2 (de) 1990-06-11 1998-03-26 Nexstar Pharmaceuticals Inc Nukleinsäureliganden
US5719273A (en) 1993-06-14 1998-02-17 Nexstar Pharmaceuticals, Inc. Palladium catalyzed nucleoside modifications methods using nucleophiles and carbon monoxide
US5945527A (en) 1996-05-30 1999-08-31 Nexstar Pharmaceuticals, Inc. Palladium catalyzed nucleoside modification methods using nucleophiles and carbon monoxide
US6242246B1 (en) 1997-12-15 2001-06-05 Somalogic, Inc. Nucleic acid ligand diagnostic Biochip
ES2371539T3 (es) * 2002-04-23 2012-01-04 Home Access Health Corporation Análisis cuantitativo de una muestra biológica de cantidad desconocida.
US7373256B2 (en) 2005-04-19 2008-05-13 Nicholson Jeremy K Method for the identification of molecules and biomarkers using chemical, biochemical and biological data
US7947447B2 (en) 2007-01-16 2011-05-24 Somalogic, Inc. Method for generating aptamers with improved off-rates
US7855054B2 (en) 2007-01-16 2010-12-21 Somalogic, Inc. Multiplexed analyses of test samples
MX2010000578A (es) 2007-07-17 2010-04-30 Somalogic Inc Metodo para generar aptameros con constantes de disociacion mejoradas.
US9551703B2 (en) * 2009-08-04 2017-01-24 The Johns Hopkins University High precision quantitative assay composition and methods of use therefor
AU2011240677B2 (en) 2010-04-12 2015-05-14 Somalogic Operating Co., Inc. 5-position modified pyrimidines and their use
CA2825196C (en) * 2011-01-21 2021-01-05 Theranos, Inc. Systems and methods for sample use maximization
EP3425090B1 (en) * 2014-02-18 2019-10-23 SomaLogic, Inc. Compositions and methods for detecting microorganisms
AU2016243656A1 (en) 2015-03-30 2017-11-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012500401A (ja) 2008-08-21 2012-01-05 バイオ−ラッド ラボラトリーズ，インコーポレイティド 分析物の比を決定する校正表面方法
JP2013528379A (ja) 2010-05-21 2013-07-11 オームクス コーポレーション Ｐｓａ酵素活性アッセイによる癌の検出

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
北山 秋雄, 外3，"パーソナルコンピュータを用いたELISA法の抗体価処理・解析システムの開発について"，千葉衛研報告，1988年，Vol.12，p.41-44 ，javascript:void(0)
原田 淳, 外，平行線検定（直線及びシグモイド曲線）による効力比較，第2期医薬安全性研究会 第21回定例会 公開資料，2017年11月18日，p.1-16，[online], [令和5年12月26日検索], インターネット＜URL：https://biostat.jp/archive_teireikai_2_download.php?id=140＞
森田 稔, 外3，"Protein-Gとモノクローナル抗体を用いたELISA法による風疹ウイルス抗体の測定について"，臨床とウイルス，1991年，Vol.19、No.2，p.135-142

Also Published As

Publication number Publication date
SG11202111365QA (en) 2021-11-29
US20220260585A1 (en) 2022-08-18
CA3140053A1 (en) 2020-11-26
BR112021022532A2 (enExample) 2021-12-28
BR112021022532A8 (pt) 2022-10-11
JP2022532212A (ja) 2022-07-13
CN113826170A (zh) 2021-12-21
CN113826170B (zh) 2024-12-27
US12480956B2 (en) 2025-11-25
IL288014A (en) 2022-01-01
AU2020278570A1 (en) 2022-01-06
EP3969900A1 (en) 2022-03-23
KR20220009948A (ko) 2022-01-25
WO2020236544A1 (en) 2020-11-26

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