JP7665628B2 - ペプチド - Google Patents

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Publication number
JP7665628B2
JP7665628B2 JP2022537314A JP2022537314A JP7665628B2 JP 7665628 B2 JP7665628 B2 JP 7665628B2 JP 2022537314 A JP2022537314 A JP 2022537314A JP 2022537314 A JP2022537314 A JP 2022537314A JP 7665628 B2 JP7665628 B2 JP 7665628B2
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JP
Japan
Prior art keywords
intein
degradation
tag
genetic construct
domain
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Active
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JP2022537314A
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English (en)
Japanese (ja)
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JP2023507409A5 (https=
JP2023507409A (ja
Inventor
タバソリ，アリ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Southampton
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University of Southampton
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Publication of JP2023507409A5 publication Critical patent/JP2023507409A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

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  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2022537314A 2019-12-18 2020-12-17 ペプチド Active JP7665628B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1918693.1 2019-12-18
GBGB1918693.1A GB201918693D0 (en) 2019-12-18 2019-12-18 Peptide
PCT/GB2020/053263 WO2021123789A1 (en) 2019-12-18 2020-12-17 Peptide

Publications (3)

Publication Number Publication Date
JP2023507409A JP2023507409A (ja) 2023-02-22
JP2023507409A5 JP2023507409A5 (https=) 2023-10-02
JP7665628B2 true JP7665628B2 (ja) 2025-04-21

Family

ID=69186767

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022537314A Active JP7665628B2 (ja) 2019-12-18 2020-12-17 ペプチド

Country Status (7)

Country Link
US (1) US20240279646A1 (https=)
EP (1) EP4077662A1 (https=)
JP (1) JP7665628B2 (https=)
CN (1) CN114867854A (https=)
CA (1) CA3164788A1 (https=)
GB (1) GB201918693D0 (https=)
WO (1) WO2021123789A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3847254A4 (en) 2018-09-07 2022-08-10 Beam Therapeutics Inc. COMPOSITIONS AND METHODS FOR DELIVERING A NUCLEOBASE EDITING SYSTEM
WO2025250838A1 (en) * 2024-05-31 2025-12-04 University Of Washington Boolean logic-gated protein presentation via autonomously compiled molecular topology

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015042159A (ja) 2013-08-26 2015-03-05 国立大学法人 東京大学 大環状ペプチド、その製造方法、及び大環状ペプチドライブラリを用いるスクリーニング方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001247296A1 (en) * 2000-03-06 2001-09-17 Rigel Pharmaceuticals, Inc. In vivo production of cyclic peptides
IL282362B2 (en) * 2018-10-15 2025-10-01 Fond Telethon Ets Intein proteins and their uses

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015042159A (ja) 2013-08-26 2015-03-05 国立大学法人 東京大学 大環状ペプチド、その製造方法、及び大環状ペプチドライブラリを用いるスクリーニング方法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ACS Chem. Biol.，2016年，11，1624-1630
Cancer Res ，2002年，62，2013-2018
Curr Opin Chem Biol，2019年06月，50，111-119
The journal of biological chemistry，2002年，277，37512-37518

Also Published As

Publication number Publication date
EP4077662A1 (en) 2022-10-26
US20240279646A1 (en) 2024-08-22
JP2023507409A (ja) 2023-02-22
CA3164788A1 (en) 2021-06-24
GB201918693D0 (en) 2020-01-29
WO2021123789A1 (en) 2021-06-24
CN114867854A (zh) 2022-08-05

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