JP7621979B2 - ウイルスベクターおよびその養子細胞療法における使用 - Google Patents

ウイルスベクターおよびその養子細胞療法における使用 Download PDF

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JP7621979B2
JP7621979B2 JP2021570189A JP2021570189A JP7621979B2 JP 7621979 B2 JP7621979 B2 JP 7621979B2 JP 2021570189 A JP2021570189 A JP 2021570189A JP 2021570189 A JP2021570189 A JP 2021570189A JP 7621979 B2 JP7621979 B2 JP 7621979B2
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マタ，メリンダ
ビュイアール，ヤニック
カルラ，マムタ
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イマティクス ユーエス，アイエヌシー．
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32—T-cell receptors [TCR]
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/34—Antigenic peptides
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    • A61K40/41—Vertebrate antigens
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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JP2021570189A 2019-05-27 2020-05-27 ウイルスベクターおよびその養子細胞療法における使用 Active JP7621979B2 (ja)

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JP2025005148A JP2025063184A (ja) 2019-05-27 2025-01-15 ウイルスベクターおよびその養子細胞療法における使用

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US201962853123P 2019-05-27 2019-05-27
US62/853,123 2019-05-27
PCT/US2020/034639 WO2020243134A1 (en) 2019-05-27 2020-05-27 Viral vectors and their use in adoptive cellular therapy

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US (2) US11975025B2 (cg-RX-API-DMAC7.html)
EP (1) EP3976805A1 (cg-RX-API-DMAC7.html)
JP (2) JP7621979B2 (cg-RX-API-DMAC7.html)
KR (1) KR20220029584A (cg-RX-API-DMAC7.html)
CN (1) CN113874516A (cg-RX-API-DMAC7.html)
AU (1) AU2020283500B2 (cg-RX-API-DMAC7.html)
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SG11202111865UA (en) * 2019-05-01 2021-11-29 Pact Pharma Inc Compositions and methods for the treatment of cancer using a tet2 engineered t cell therapy
PH12021553152A1 (en) * 2019-06-18 2022-08-15 Regeneron Pharma Mage-a4 t cell receptors and methods of use thereof
DE102020111571A1 (de) 2020-03-11 2021-09-16 Immatics US, Inc. Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
TW202241938A (zh) * 2020-12-31 2022-11-01 美商英麥提克斯股份有限公司 Ｃｄ８多肽、組合物及其使用方法
WO2022233956A1 (en) 2021-05-05 2022-11-10 Immatics Biotechnologies Gmbh Antigen binding proteins specifically binding prame
US20230190806A1 (en) * 2021-10-06 2023-06-22 Immatics Biotechnologies Gmbh Methods of treating metastatic lesions and compositions thereof
EP4448108A1 (en) * 2021-11-08 2024-10-23 Immatics Biotechnologies GmbH Adoptive cell therapy combination treatment and compositions thereof
EP4472742A1 (en) * 2022-02-03 2024-12-11 University College Cardiff Consultants Limited Novel t-cell receptor
US20230348561A1 (en) * 2022-04-28 2023-11-02 Immatics US, Inc. Dominant negative tgfbeta receptor polypeptides, cd8 polypeptides, cells, compositions, and methods of using thereof
EP4501954A1 (en) * 2023-08-02 2025-02-05 Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft A nucleic acid encoding a cd8 alpha beta co-receptor, cells and pharmaceutical compositions comprising the same
CN117777314B (zh) * 2024-02-26 2024-05-14 赛德特生物制药有限公司 慢病毒载体及其应用
WO2026008886A1 (en) 2024-07-05 2026-01-08 Immatics Biotechnologies Gmbh Means and methods for the quantification of target expression
WO2026033136A1 (en) 2024-08-09 2026-02-12 Immatics Biotechnologies Gmbh Advanced treatment modalities for anti-prame tcr-engineered immune cells

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