JP7576037B2 - Ｔ細胞受容体及びその使用方法 - Google Patents

Ｔ細胞受容体及びその使用方法 Download PDF

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JP7576037B2
JP7576037B2 JP2021552605A JP2021552605A JP7576037B2 JP 7576037 B2 JP7576037 B2 JP 7576037B2 JP 2021552605 A JP2021552605 A JP 2021552605A JP 2021552605 A JP2021552605 A JP 2021552605A JP 7576037 B2 JP7576037 B2 JP 7576037B2
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hla
tcr
amino acid
acid sequence
seq
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JP2022524994A (ja
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直人 平野
憲治 村田
薫葉子 佐相
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ユニバーシティー ヘルス ネットワーク
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/00119—Melanoma antigens
    • A61K39/001192—Glycoprotein 100 [Gp100]
    • A—HUMAN NECESSITIES
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    • A61K35/14—Blood; Artificial blood
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    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
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JP2021552605A 2019-03-04 2020-03-03 Ｔ細胞受容体及びその使用方法 Active JP7576037B2 (ja)

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Application Number Priority Date Filing Date Title
US201962813651P 2019-03-04 2019-03-04
US62/813,651 2019-03-04
PCT/IB2020/051813 WO2020178744A1 (en) 2019-03-04 2020-03-03 T cell receptors and methods of use thereof

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JP2022524994A JP2022524994A (ja) 2022-05-11
JP2022524994A5 JP2022524994A5 (https=) 2023-03-13
JP7576037B2 true JP7576037B2 (ja) 2024-10-30

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US (1) US12611450B2 (https=)
EP (1) EP3935172A4 (https=)
JP (1) JP7576037B2 (https=)
KR (1) KR20210144737A (https=)
CN (1) CN113785065B (https=)
AU (1) AU2020231694A1 (https=)
BR (1) BR112021017479A2 (https=)
CA (1) CA3132438A1 (https=)
IL (1) IL286044A (https=)
MX (1) MX2021010537A (https=)
SG (1) SG11202109595TA (https=)
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Families Citing this family (6)

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Publication number Priority date Publication date Assignee Title
EP3935175A4 (en) 2019-03-04 2023-01-04 University Health Network T-LYMPHOCYTE RECEPTORS AND METHODS OF USE THEREOF
CN113795584B (zh) 2019-03-04 2025-09-30 大学健康网络 T细胞受体及其使用方法
KR20210144737A (ko) 2019-03-04 2021-11-30 유니버시티 헬스 네트워크 T 세포 수용체 및 이의 사용 방법
MX2021011462A (es) 2019-03-25 2021-12-15 Univ Health Network Receptores de linfocitos t y metodos de uso de los mismos.
WO2025085855A2 (en) * 2023-10-20 2025-04-24 BioNTech SE Multispecific t cell engagers compositions and methods of use thereof
CN117624340B (zh) * 2024-01-23 2024-04-30 北京臻知医学科技有限责任公司 识别人乙型肝炎病毒（hbv）抗原的t细胞受体（tcr）及其用途

Citations (3)

* Cited by examiner, † Cited by third party
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US20100015113A1 (en) 2007-01-12 2010-01-21 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Gp100-specific t cell receptors and related materials and methods of use
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