JP7514111B2 - Column connection parts - Google Patents
Column connection parts Download PDFInfo
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- JP7514111B2 JP7514111B2 JP2020090379A JP2020090379A JP7514111B2 JP 7514111 B2 JP7514111 B2 JP 7514111B2 JP 2020090379 A JP2020090379 A JP 2020090379A JP 2020090379 A JP2020090379 A JP 2020090379A JP 7514111 B2 JP7514111 B2 JP 7514111B2
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 51
- 238000003466 welding Methods 0.000 claims description 22
- 239000000463 material Substances 0.000 claims description 14
- 238000005304 joining Methods 0.000 claims description 8
- 238000001746 injection moulding Methods 0.000 claims description 7
- 210000003734 kidney Anatomy 0.000 claims description 5
- 210000004185 liver Anatomy 0.000 claims description 5
- 210000004072 lung Anatomy 0.000 claims description 5
- 229920005672 polyolefin resin Polymers 0.000 claims description 5
- 239000012503 blood component Substances 0.000 claims description 4
- 210000000265 leukocyte Anatomy 0.000 claims description 4
- -1 polypropylene Polymers 0.000 claims description 4
- 239000004743 Polypropylene Substances 0.000 claims description 3
- 239000003463 adsorbent Substances 0.000 claims description 3
- 229920013716 polyethylene resin Polymers 0.000 claims description 3
- 229920001155 polypropylene Polymers 0.000 claims description 3
- 229920005989 resin Polymers 0.000 claims description 3
- 239000011347 resin Substances 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 230000001954 sterilising effect Effects 0.000 description 12
- 238000004659 sterilization and disinfection Methods 0.000 description 12
- 239000007788 liquid Substances 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 230000007547 defect Effects 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 238000004806 packaging method and process Methods 0.000 description 3
- 210000003200 peritoneal cavity Anatomy 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000000385 dialysis solution Substances 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 239000000306 component Substances 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000010894 electron beam technology Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000012779 reinforcing material Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 229920002725 thermoplastic elastomer Polymers 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
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- External Artificial Organs (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
本発明は、カラム用連結部材に関する。 The present invention relates to a column connection member.
医療分野や浄化器分野の液体を処理する器具の容器は、内圧が高くなっても液漏れを起こさない様に、高い気密性や耐圧強度が要求されている。その容器には、安全性が高いためルアーロック型のノズルが広く利用されており、その場合は、一般的に、ルアーロック構造をもつ容器の凹ねじに対応するねじ部を有する栓体が、該容器に具備される。 Containers for devices that process liquids in the medical and purifying fields are required to be highly airtight and pressure resistant to prevent liquid leakage even when the internal pressure is high. Luer lock nozzles are widely used for such containers because of their high safety. In such cases, the container is generally equipped with a stopper that has a threaded portion that corresponds to the concave thread of the container with a Luer lock structure.
特許文献１には、ルアーロック接続機構が設けられた血液の供給・排出ポートを有する血液浄化器が複数直列に接続されてなる血液浄化システムについて開示されている。 Patent Document 1 discloses a blood purification system in which multiple blood purifiers, each having a blood supply/discharge port with a Luer lock connection mechanism, are connected in series.
また、特許文献２には、第１部材と第２部材とを容易に接続することができる医療用コネクタについて開示されている。 Patent document 2 also discloses a medical connector that can easily connect a first member and a second member.
さらに、特許文献３には、透析液容器、および患者の腹膜腔の中に挿入されるカテーテルに簡単にかつ容易に取り付け可能なコネクタおよびキャップについて開示されており、コネクタおよびキャップは、例えば使用中の取り扱いのために腹膜腔内における感染の可能性を最小にしながら、容器と腹膜腔との間で透析液が容易に輸送されることを可能にするなどの記載がある。 Furthermore, Patent Document 3 discloses a connector and cap that can be simply and easily attached to a dialysis fluid container and a catheter that is inserted into a patient's peritoneal cavity, and describes that the connector and cap allow dialysis fluid to be easily transported between the container and the peritoneal cavity while minimizing the possibility of infection in the peritoneal cavity due to handling during use, for example.
しかしながら、特許文献１、特許文献２、および特許文献３に記載のシステムは、ノズルを有するカラム内を通水することにより滅菌をした後、封止状態を維持したまま、当該カラムを個別にとりだすことができないなどの課題があった。 However, the systems described in Patent Documents 1, 2, and 3 have problems, such as the inability to individually remove a column having a nozzle after sterilization by passing water through the column while maintaining the sealed state.
本発明は、上記の問題点を解決し、ノズルを有するカラム内を通水することにより滅菌をした後、封止状態を維持したまま、当該カラムを個別に取り出すことが可能な部材を提供することにある。 The present invention aims to solve the above problems and provide a component that allows a column having a nozzle to be sterilized by passing water through it, and then the column can be removed individually while maintaining the sealed state.
具体的には、本発明は以下の発明を包含する。
[１] カラムと連結することが可能なカラム用連結部材であって、前記カラム用連結部材は、前記カラムと連結するためのカラム連結部、前記カラム用連結部材同士あるいはカラム用連結部材と通水設備を接合するための接合部、内部を通水することが可能な通水部、及び通水部を溶着することのできる溶着部を有することを特徴とするカラム用連結部材。
[２] 前記カラム用連結部材が、射出成型で成形可能な材料で構成されていることを特徴とする、[１]に記載のカラム用連結部材。
[３] 前記射出成型で成形可能な材料が、ポリオレフィン樹脂であることを特徴とする、[２]に記載のカラム用連結部材。
[４] 前記ポリオレフィン樹脂が、ポリプロピレン樹脂、ポリエチレン樹脂であることを特徴とする、[３]に記載のカラム用連結部材。
[５] 前記カラム用連結部材を、カラム同士を連結させるため、あるいはカラムと通水設備を連結させるために使用することを特徴とする、[１]～[４]に記載のカラム用連結部材。
[６] 前記カラム連結部がねじリブを有することを特徴とする、[１]～[５]に記載のカラム用連結部材。
[７] 前記溶着部の外側にリブを有することを特徴とする、[１]～[６]に記載のカラム用連結部材。
[８] 前記リブを２本以上有することを特徴とする、[７]に記載のカラム用連結部材。
[９] 前記カラム用連結部材同士の接合が、カラム用連結部材（オス）の接合部（オス）とカラム用連結部材（メス）の接合部（メス）の接合であることを特徴とする、[１]～[８]に記載のカラム用連結部材。
[１０] 前記カラムが、白血球除去器、血液成分吸着材、プラズマセパレータ、人工腎臓、人工肝臓、人工肺、血漿分離器、限外濾過器、及び浄水器から選ばれる少なくとも一つであることを特徴とする、[１]～[９]に記載のカラム用連結部材。
[１１] [１]～[１０]のカラム用連結部材が連結されたカラムであって、前記カラム用連結部材が前記溶着部において溶着されていることにより、前記カラムが封止されている、カラム。
[１２] [１]～[１０]のカラム用連結部材によりカラムと通水設備を連結する工程、
前記カラムの内部を通水し滅菌をする工程、
前記カラム用連結部材の溶着部を溶着する工程、及び
前記カラム用連結部材の接合部を取り外し、封止されたカラムを得る工程、
を含む、カラムの製造方法。
Specifically, the present invention includes the following inventions.
[1] A column connecting member capable of being connected to a column, the column connecting member having a column connecting portion for connecting to the column, a joint portion for joining the column connecting members to each other or to a water passage facility, a water passage portion through which water can pass, and a welding portion for welding the water passage portion.
[2] The column connecting member according to [1], characterized in that the column connecting member is made of a material that can be molded by injection molding.
[3] The column connecting member according to [2], wherein the material that can be molded by injection molding is a polyolefin resin.
[4] The column connecting member according to [3], wherein the polyolefin resin is a polypropylene resin or a polyethylene resin.
[5] The column connecting member according to any one of [1] to [4], which is used for connecting columns to each other or for connecting a column to a water passage facility.
[6] The column connecting member according to any one of [1] to [5], wherein the column connecting portion has a twisted rib.
[7] The column connecting member according to any one of [1] to [6], further comprising a rib on the outside of the welded portion.
[8] The column connecting member according to [7], characterized in having two or more of the ribs.
[9] The column connecting member according to any one of [1] to [8], characterized in that the joining of the column connecting members is between a joint (male) of a column connecting member (male) and a joint (female) of a column connecting member (female).
[10] The column connecting member according to any one of [1] to [9], characterized in that the column is at least one selected from a leukocyte removal device, a blood component adsorbent, a plasma separator, an artificial kidney, an artificial liver, an artificial lung, a plasma separator, an ultrafilter, and a water purifier.
[11] A column to which the column connecting member according to any one of [1] to [10] is connected, wherein the column connecting member is welded at the welded portion, thereby sealing the column.
[12] A step of connecting the column and the water flow equipment using the column connecting members of [1] to [10];
a step of passing water through the inside of the column to sterilize it;
a step of welding the welded portion of the column connecting member, and a step of removing the joint portion of the column connecting member to obtain a sealed column;
A method for manufacturing a column, comprising:
ノズルを有するカラム内を通水することにより滅菌をした後、封止状態を維持したまま、当該カラムを個別に取り出すことができる。 After sterilization by passing water through a column with a nozzle, the column can be removed individually while still remaining sealed.
本発明のカラム用連結部材は、カラムと通水設備を連結させるために使用することができる。また、カラム同士を連結させるためにも使用することができる。 The column connecting member of the present invention can be used to connect a column to a water passage facility. It can also be used to connect columns to each other.
本発明のカラム用連結部材には、カラム用連結部材（オス）とカラム用連結部材（メス）の２種類があり、それらは互いに連結させることが可能である。 The column connecting members of the present invention are of two types: column connecting members (male) and column connecting members (female), which can be connected to each other.
以下、図面を参照しながら、本発明に係るカラム用連結部材の一実施形態について説明するが、本発明はこれらに限定されるものではない。 Below, an embodiment of a column connecting member according to the present invention will be described with reference to the drawings, but the present invention is not limited thereto.
図１は、カラム用連結部材（オス）１を正面から見た図として示すものであり、カラム本体のノズルに挿入する前の状態を示している。図２は、カラム用連結部材（オス）１を右側面から見た状態を示している。この図では、接合部（オス）４を手前にしているものである。図３は、カラム用連結部材（オス）１を上面から見た状態を示しているものである。 Figure 1 shows the column connecting member (male) 1 as seen from the front, showing the state before it is inserted into the nozzle of the column body. Figure 2 shows the column connecting member (male) 1 as seen from the right side. In this figure, the joint (male) 4 is facing forward. Figure 3 shows the column connecting member (male) 1 as seen from the top.
カラム用連結部材（オス）１は、カラム連結部９、通水部、溶着部３、及び接合部（オス）４を有する。 The column connecting member (male) 1 has a column connecting portion 9, a water passage portion, a welding portion 3, and a joint portion (male) 4.
カラム連結部９はカラムと連結する部分であり、カラムと連結可能であればその構造に特に制限はないが、ねじリブ６を有する構造であることが好ましい。ノズル側の内周壁に凹ねじが刻まれたカラムを使用した場合、該凹ねじにカラム用連結部材（オス）１のねじリブ６が螺合して両者（カラム本体とカラム用連結部材）を一体化することができる。また後述するが、接合部（オス）４をカラム用連結部材（メス）２の接合部（メス）７に接合することでシール性を生み出し、内液の通水が可能となる。 The column connecting part 9 is a part that connects to the column, and there are no particular limitations on its structure as long as it can be connected to the column, but a structure with a screw rib 6 is preferable. When a column with a concave thread engraved on the inner peripheral wall on the nozzle side is used, the screw rib 6 of the column connecting member (male) 1 can be screwed into the concave thread to integrate the two (column body and column connecting member). As will be described later, by joining the joint (male) 4 to the joint (female) 7 of the column connecting member (female) 2, a seal is created, allowing the internal liquid to pass through.
前記ねじリブ６の形状は、カラム本体のノズルと螺合するものであれば特に制限はないが、ルアーロック型のコネクタに使用可能な形状であることが好ましい。ここでルアーロックとは、ＩＳＯ５９４－２で規定される固定方法であり、ねじ込み式で外れにくい特徴をもつ。 The shape of the screw rib 6 is not particularly limited as long as it can be screwed into the nozzle of the column body, but it is preferable that the shape be usable for a lure lock type connector. Here, lure lock is a fastening method defined in ISO594-2, and is characterized by being a screw-in type that is difficult to come off.
カラム用連結部材（オス）１の内部は、内液を通水できるような通水部を有している。これにより、カラム用連結部材によりカラムを通水装置と連結した際に、前記カラムに内液を通水し滅菌をすることができる。 The inside of the column connecting member (male) 1 has a water passage part that allows the internal liquid to pass through. This allows the internal liquid to pass through the column and sterilize it when the column is connected to a water passage device using the column connecting member.
前記通水部は、溶着が可能である溶着部３を有する。前記通水滅菌した後に溶着部３を溶着することにより、通水部が密封され、個々のカラムを封止状態とすることができる。 The water passage section has a welding section 3 that can be welded. By welding the welding section 3 after the water passage sterilization, the water passage section is sealed, and each column can be sealed.
前記溶着方法としては、超音波溶着、熱溶着など種々の溶着方法が使用できるが、タクトタイムや仕上がりの観点から、超音波溶着が好ましい。 Various welding methods can be used as the welding method, such as ultrasonic welding and heat welding, but ultrasonic welding is preferred from the standpoint of takt time and finish.
カラム用連結部材（オス）１の溶着部３の外側にはリブ５が配置されていることが好ましい。ここでリブとは補強材の役割を成すものであり、後述するが、滅菌中の高温高圧下においても溶着部３が変形しないよう支えている部材である。 It is preferable that a rib 5 is disposed on the outside of the welded portion 3 of the column connecting member (male) 1. Here, the rib acts as a reinforcing material, and as will be described later, is a member that supports the welded portion 3 so that it does not deform even under the high temperature and pressure during sterilization.
さらに、前記リブが配置されていることにより、溶着部を溶着させた際に生じる溶着部のバリなどがリブの外側に露出することを防ぎ、個々の封止済みカラムを包装袋に包装する際にバリなどが包装袋に接触して、穴あきの発生源となることを防ぐことができる。また、個々の封止済みのカラムを現場で使用する際に、手指を溶着部のバリなどで痛めることを防ぐことができる。 Furthermore, the presence of the rib prevents burrs and other defects from being exposed to the outside of the rib when welding the welded parts, and prevents the burrs and other defects from coming into contact with the packaging bag when packaging each sealed column in a packaging bag, which can cause holes. It also prevents fingers from being injured by burrs and other defects when using each sealed column on-site.
前記リブの本数には特に制限はないが、前記バリの露出の抑制の効果を得る観点から、２本以上が好ましく、また溶着部の溶着のし易さの観点から４本以下が好ましい。特に好ましくは、２本である。 There is no particular limit to the number of ribs, but from the viewpoint of obtaining the effect of suppressing the exposure of burrs, two or more are preferable, and from the viewpoint of ease of welding of the welded portion, four or less are preferable. Two ribs are particularly preferable.
前記接合部（オス）４の形状は、後述する接合部（メス）７に接合することのできる形状であれば特に制限はないが、ルアーテーパが好ましい。ルアーテーパとはＩＳＯ５９４－１に規定される形状である。 There are no particular limitations on the shape of the male joint 4 as long as it can be joined to the female joint 7 described below, but a lure taper is preferred. A lure taper is a shape specified in ISO 594-1.
カラム用連結部材（オス）の材質に特に制限はないが、射出成形機で成形できるものが好ましい。ここで、射出成型機で成形できるとは、通常の一般的な条件で射出成型ができることを意味する。好ましい材質としては、ポリオレフィン樹脂が挙げられる。その中でも密封性や成形しやすさ及び低コストであることから、ポリプロピレン樹脂、ポリエチレン樹脂が好ましく用いられる。 There are no particular restrictions on the material of the column connecting member (male), but it is preferable that it be made of a material that can be molded using an injection molding machine. Here, being able to be molded using an injection molding machine means that it can be injection molded under normal general conditions. Preferred materials include polyolefin resins. Among these, polypropylene resins and polyethylene resins are preferably used because of their sealing properties, ease of molding, and low cost.
カラム用連結部材（オス）を構成する材料は全て同一の材料であっても良いし、部分的に異なる材料を組み合わせても良い。好ましくは、全て同一の材料であることが、射出成型機で一体に成形することが可能となるため好ましい。 The materials constituting the column connecting member (male) may all be the same material, or may be a combination of partially different materials. It is preferable that all be the same material, since this allows for integral molding using an injection molding machine.
図４は、カラム用連結部材（メス）４を正面から見た図として示すものであり、カラム本体のノズルに挿入する前の状態を示している。 Figure 4 shows the column connecting member (female) 4 as seen from the front, showing the state before it is inserted into the nozzle of the column body.
カラム用連結部材（メス）４は接合部（オス）４ではなく接合部（メス）７を有している点以外はカラム用連結部材（オス）１と構造、材料等の特徴は同じである。この接合部（メス）７を接合部（オス）４に接合することでシール性を生み出し、内液の通水を可能にしている。 The column connecting member (female) 4 has the same structure, materials, and other characteristics as the column connecting member (male) 1, except that it has a connecting member (female) 7 instead of a connecting member (male) 4. By joining this connecting member (female) 7 to the connecting member (male) 4, a seal is created, allowing the internal liquid to pass through.
接合部（メス）７の形状は、後述する接合部（オス）４に接合することのできる形状であれば特に制限はないが、ルアーテーパが好ましい。ルアーテーパとはＩＳＯ５９４－１に規定される形状である。 There are no particular limitations on the shape of the female joint 7 as long as it can be joined to the male joint 4 described below, but a lure taper is preferred. A lure taper is a shape specified in ISO 594-1.
図５は、カラム用連結部材（オス）１とカラム用連結部材（メス）２を接合した状態を示すものであり、接合部（オス）４を接合部（メス）７にはめ込んで、接合部(接合時)８のようになっている。この状態でカラム連結部９がカラムのノズルに接続していることで、内液通水を可能にするものである。 Figure 5 shows the state in which a column connecting member (male) 1 and a column connecting member (female) 2 are joined, with the connecting part (male) 4 fitted into the connecting part (female) 7 to form the connecting part (connected) 8. In this state, the column connecting part 9 is connected to the nozzle of the column, allowing the internal liquid to pass through.
図６は、各カラム用連結部材を用いて複数のカラムを連結させた時の図である。内液を互いに通水できる状態で滅菌をした後、溶着部３を溶着し、その後接合部（オス）と接合部（メス）が接合した接合部（接合時）８を取り外すことで、封止状態を維持したまま、カラムを個別に取り出すことができる。 Figure 6 shows multiple columns connected together using each column connection member. After sterilization so that the internal fluid can flow through each other, the welded parts 3 are welded together, and then the joint part (male) and the joint part (female) are joined at the joint part (when joined) 8, which is removed, allowing the columns to be removed individually while maintaining the sealed state.
カラムを連結させた状態において、滅菌のためカラムを高温高圧環境下に曝した場合、カラムの自重により、カラム用連結部材が変形する恐れがある。この変形を回避するためにリブ５を設けており、変形に耐えうる強度を実現している。 When columns are connected and exposed to a high-temperature, high-pressure environment for sterilization, the weight of the columns may cause the column connection members to deform. Ribs 5 are provided to prevent this deformation, providing the strength to withstand deformation.
カラム用連結部材同士を接合させるのに、本発明のカラム用連結部材を用いずに、塩化ビニルや熱可塑性エラストマーでできたチューブを使用して接合する方法も考えられる。チューブを使用すると、カラムの配置を柔軟に行えるなどメリットも挙げられるが通水滅菌後に当該チューブは不要となるため、廃棄物が増える観点から好ましくない。本発明のカラム用連結部材を用いると、当該チューブの費用が無くなる分、安価とすることができる。 It is also possible to join column connecting members together using tubes made of polyvinyl chloride or thermoplastic elastomers, rather than using the column connecting member of the present invention. Using tubes has the advantage of allowing for flexible column placement, but is not preferable in terms of increasing waste, as the tubes become unnecessary after water sterilization. Using the column connecting member of the present invention eliminates the cost of the tubes, making it cheaper.
また、チューブを用いないことにより、自動機（マシン）によるハンドリングしやすさが向上し、工程を自働化しやすくなるメリットが挙げられる。 Another advantage of not using tubes is that it is easier to handle using automated machines, making it easier to automate the process.
本発明のカラム用連結部材が連結されたカラムに通水するための通水設備としては、特に制限はないが、カラム用連結部材が接合可能であるものであることが好ましい。例えば、通水設備にカラム用連結部材の接合部と接合可能な接合部を設けることにより、カラム用連結部材を通水設備と接合することが可能となり、通水設備とカラムを連結することができる。 There are no particular limitations on the water passage equipment for passing water through a column to which the column connecting member of the present invention is connected, but it is preferable that the column connecting member can be joined. For example, by providing the water passage equipment with a joint that can be joined to the joint of the column connecting member, it becomes possible to join the column connecting member to the water passage equipment, and the water passage equipment and the column can be connected.
本発明のカラム用連結部材が用いられ得るカラムとしては、例えば、白血球除去器、血液成分吸着材、プラズマセパレータ、人工腎臓、人工肝臓、人工肺、血漿分離器、限外濾過器、浄水器等が挙げられる。これらの機器の内部には、注射用蒸留水、イオン交換水、限外濾過水等の水、生理食塩水、緩衝液、輸液、透析液等の塩を含有する水溶液に例示される流体が充填される。 Columns for which the column connecting member of the present invention can be used include, for example, leukocyte removers, blood component adsorbents, plasma separators, artificial kidneys, artificial livers, artificial lungs, plasma separators, ultrafilters, water purifiers, etc. The interior of these devices is filled with fluids such as water for injection, ion-exchanged water, ultrafiltered water, etc., and aqueous solutions containing salts such as physiological saline, buffer solutions, infusions, and dialysis fluids.
これらのうち、人工腎臓、人工肝臓、人工肺等の滅菌方法としては、高圧蒸気滅菌、加熱滅菌、放射線滅菌、電子線滅菌等が用いられる。これらは、いずれも加熱を伴い、医療用具内の内圧が内容液体の膨張のため上昇することから、高い耐圧気密性が要求される。 Of these, methods of sterilization for artificial kidneys, artificial livers, artificial lungs, etc. include high-pressure steam sterilization, heat sterilization, radiation sterilization, and electron beam sterilization. All of these methods involve heating, and the internal pressure of the medical device rises due to the expansion of the liquid contained within, so high pressure-resistance and airtightness are required.
また、本発明のカラム用連結部材が使用できるコネクタは特に制限はないが、例えばルアーロック型のコネクタに使用でき、特にＩＳＯ５９４－２ルアーロック型コネクタに好適に使用できる。このため、この規格のルアーロック型コネクタを有しているカラムに対して、本発明のカラム用連結部材（封止栓）を具備することが最も好ましい。 The column connecting member of the present invention can be used with any connector, but it can be used with luer lock connectors, for example, and is particularly suitable for ISO594-2 luer lock connectors. For this reason, it is most preferable to equip a column having a luer lock connector of this standard with the column connecting member (sealing plug) of the present invention.
本発明のカラム用連結部材と、該カラム用連結部材を具備するカラムは、例えば、白血球除去器、血液成分吸着、プラズマセパレータ、人工腎臓、人工肝臓、人工肺、血漿分離器、限外濾過器、浄水器などの医療材料分野、浄水化技術分野などで利用することができる。 The column connecting member of the present invention and a column equipped with the column connecting member can be used, for example, in the medical materials field, water purification technology field, etc., such as leukocyte removal devices, blood component adsorption, plasma separators, artificial kidneys, artificial livers, artificial lungs, plasma separators, ultrafilters, and water purifiers.
１：カラム用連結部材（オス）
２：カラム用連結部材（メス）
３：溶着部
４：接合部（オス）
５：リブ
６：ねじリブ
７：接合部（メス）
８：接合部（接合時）
９：カラム連結部
1: Column connecting member (male)
2: Column connection member (female)
3: Welded part 4: Joint part (male)
5: Rib 6: Twist rib 7: Joint (female)
8: Joint (when joined)
9: Column connection part
Claims (12)
前記カラムに連結されているカラム用連結部材と、を有し、a column connecting member connected to the column,
前記カラム用連結部材は、前記カラムと連結されているカラム連結部、前記カラム用連結部材の内部を通水することが可能な通水部、他のカラム用連結部材及び／又は通水設備と接合するための接合部であって通水設備と接合されている接合部、及び前記通水部の内部を溶着によって密封している溶着部を有する、封止されたカラム。The column connecting member is a sealed column having a column connecting portion connected to the column, a water passing portion that allows water to pass through the inside of the column connecting member, a joint portion for joining to another column connecting member and/or water passing equipment and which is joined to water passing equipment, and a welding portion that seals the inside of the water passing portion by welding.
前記カラムの内部を通水し滅菌をする工程、
前記カラム用連結部材の前記溶着部を溶着する工程、及び
前記カラム用連結部材の前記接合部を取り外し、封止されたカラムを得る工程、
を含む、封止されたカラムの製造方法。 a step of connecting a column and a water passage facility by a column connecting member capable of being connected to a column, the column connecting member having a column connecting portion for connecting to the column, a joint portion for joining the column connecting members to each other or to the column connecting member and the water passage facility, a water passage portion that allows water to pass through the inside of the column connecting member, and a welding portion made of a material that can be welded to seal the inside of the water passage portion;
a step of passing water through the inside of the column to sterilize it;
a step of welding the welded portion of the column connecting member; and a step of removing the joint portion of the column connecting member to obtain a sealed column.
A method for producing a sealed column comprising:
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000126288A (en) | 1998-10-26 | 2000-05-09 | Terumo Corp | Bag for peritoneal dialysis |
| JP2006340957A (en) | 2005-06-10 | 2006-12-21 | Asahi Kasei Medical Co Ltd | Coupler for medical instrument, and medical instrument |
| JP2018157896A (en) | 2017-03-22 | 2018-10-11 | 日機装株式会社 | Medical connector |
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- 2020-05-25 JP JP2020090379A patent/JP7514111B2/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000126288A (en) | 1998-10-26 | 2000-05-09 | Terumo Corp | Bag for peritoneal dialysis |
| JP2006340957A (en) | 2005-06-10 | 2006-12-21 | Asahi Kasei Medical Co Ltd | Coupler for medical instrument, and medical instrument |
| JP2018157896A (en) | 2017-03-22 | 2018-10-11 | 日機装株式会社 | Medical connector |
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