JP7476165B2 - がんに対するｂ＊０７拘束性ペプチドおよびペプチド組み合わせによる免疫療法 - Google Patents

がんに対するｂ＊０７拘束性ペプチドおよびペプチド組み合わせによる免疫療法 Download PDF

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JP7476165B2
JP7476165B2 JP2021500808A JP2021500808A JP7476165B2 JP 7476165 B2 JP7476165 B2 JP 7476165B2 JP 2021500808 A JP2021500808 A JP 2021500808A JP 2021500808 A JP2021500808 A JP 2021500808A JP 7476165 B2 JP7476165 B2 JP 7476165B2
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cancer
peptide
cell
cells
peptides
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JP2021535900A (ja
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シュスター，ハイコ
ダニエル，コバレフスキ
スホール，オリバー
フリッチェ，イェンス
ヴァインシェンク，トニ
シン，ハープリート
シマック，ギーゼラ
レーマー，ミヒャエル
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イマティクス バイオテクノロジーズ ゲーエムベーハー
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
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    • A61K40/42—Cancer antigens
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • C07K16/2833—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
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JP2021500808A 2018-07-31 2019-07-30 がんに対するｂ＊０７拘束性ペプチドおよびペプチド組み合わせによる免疫療法 Active JP7476165B2 (ja)

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JP2024067072A JP2024099639A (ja) 2018-07-31 2024-04-17 がんに対するｂ＊０７拘束性ペプチドおよびペプチド組み合わせによる免疫療法

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Application Number Priority Date Filing Date Title
US201862712691P 2018-07-31 2018-07-31
DE102018118550.2 2018-07-31
US62/712,691 2018-07-31
DE102018118550 2018-07-31
US201862717462P 2018-08-10 2018-08-10
DE102018119555.9 2018-08-10
DE102018119555 2018-08-10
US62/717,462 2018-08-10
PCT/EP2019/070430 WO2020025576A1 (en) 2018-07-31 2019-07-30 Immunotherapy with b*07 restricted peptides and combination of peptides against cancers and related methods

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JP2021535900A5 JP2021535900A5 (https=) 2022-08-08
JP7476165B2 true JP7476165B2 (ja) 2024-04-30

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JP2024067072A Pending JP2024099639A (ja) 2018-07-31 2024-04-17 がんに対するｂ＊０７拘束性ペプチドおよびペプチド組み合わせによる免疫療法

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EA201992416A1 (ru) * 2017-04-10 2020-02-25 Имматикс Байотекнолоджиз Гмбх Пептиды и комбинации пептидов для применения в иммунотерапии лейкозов и других видов рака
WO2018189148A1 (en) * 2017-04-10 2018-10-18 Immatics Biotechnologies Gmbh Peptides and combination thereof for use in the immunotherapy against cancers
TW202016131A (zh) * 2018-05-16 2020-05-01 德商英麥提克生物技術股份有限公司 用於抗癌免疫治療的肽
TW202019955A (zh) 2018-07-31 2020-06-01 德商英麥提克生物技術股份有限公司 B*07 限制肽和肽組合的抗癌免疫治療和相關方法
EP4103584A4 (en) * 2020-02-12 2024-08-07 La Jolla Institute for Immunology NOVEL CORONAVIRUS T-CELL EPITOPES AND RELATED USES
CA3173666A1 (en) * 2020-04-14 2021-10-21 Claude Perreault Novel tumor-specific antigens for acute myeloid leukemia (aml) and uses thereof
IL297419B2 (en) 2020-04-22 2025-02-01 BioNTech SE Coronavirus vaccine
JP2024501482A (ja) * 2020-12-14 2024-01-12 ビオンテック ユーエス インコーポレイテッド がん免疫療法のための組織特異的抗原
TW202241925A (zh) 2021-01-15 2022-11-01 德商英麥提克生物技術股份有限公司 用於不同類型癌症免疫治療的ｈｌａ展示肽
US12186387B2 (en) 2021-11-29 2025-01-07 BioNTech SE Coronavirus vaccine
WO2024002985A1 (en) 2022-06-26 2024-01-04 BioNTech SE Coronavirus vaccine

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WO2017097699A1 (en) 2015-12-11 2017-06-15 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against various cancers
WO2017202806A1 (en) 2016-05-25 2017-11-30 Immatics Biotechnologies Gmbh Novel peptides, combination of peptides as targets and for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers
JP2018519243A (ja) 2015-03-27 2018-07-19 イマティクス バイオテクノロジーズ ゲーエムベーハー 様々な腫瘍に対する免疫療法で使用される新規ペプチドおよびペプチドの組み合わせ

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