JP7434778B2 - liquid injection port - Google Patents

Description

The present invention relates to liquid injection port systems and liquid injection ports.

BACKGROUND OF THE INVENTION Liquid injection ports that are implanted into the body are known. The liquid injection port has a liquid reservoir inside that temporarily stores liquid supplied from outside the body. When a liquid supply needle is inserted into the liquid reservoir from outside the body to supply liquid to the liquid reservoir, the liquid is introduced to the catheter via the liquid introduction connector, and is supplied from the catheter to a desired location within the body.
As such a liquid injection port, for example, there is one described in Patent Document 1.

JP 2016-10563 Publication

The inventors of the present application considered that there is a need for recognizing the position of a liquid injection port from outside the body.

The present invention has been made in view of the above problems, and provides a liquid injection port system and a liquid injection port that allow the position of the liquid injection port to be recognized from outside the body.

The present invention provides a housing portion having a recess that forms a liquid reservoir for temporarily storing liquid supplied from outside the body, a plug that closes an upper opening of the recess, and a housing that communicates with the liquid reservoir. a liquid injection port that is embedded in the body and includes a liquid introduction connector that is connected to a cage catheter; and a metal member;
a port detection device for detecting the position of the liquid injection port, the port detection device comprising a detection section that detects generation of an eddy current in the metal member of the liquid injection port;
The liquid injection port in a liquid injection port system comprising :
further comprising a metal frame holding the plug,
The thickness of the metal member is larger than the thickness of the frame,
The present invention provides a liquid injection port in which the metal member is disposed above the frame .

According to the present invention, it is possible to recognize the position of the liquid injection port from outside the body.

FIG. 2 is a perspective view of a liquid injection port according to the first embodiment. FIG. 3 is a plan view of the liquid injection port according to the first embodiment. FIG. 3 is a side sectional view of the liquid injection port according to the first embodiment. FIG. 1 is a diagram showing a block configuration of a liquid injection port system according to a first embodiment. FIG. 7 is a plan view of a liquid injection port according to a second embodiment.

Embodiments of the present invention will be described below with reference to the drawings. In addition, in all the drawings, the same reference numerals are given to the same components, and the explanation is omitted as appropriate.

[First embodiment]
First, a first embodiment will be described using FIGS. 1 to 4.
As shown in FIG. 4, the liquid injection port system 300 according to the present embodiment includes a liquid injection port 100 that is implanted in the body and a port detection device 200 for detecting the position of the liquid injection port 100. A liquid injection port system 300 comprising:
As shown in any of FIGS. 1 to 3, the liquid injection port 100 includes a housing part 10 having a recess that forms a liquid reservoir 50 that temporarily stores liquid supplied from outside the body, and an upper opening of the recess. It includes a plug body 20 that closes the opening 56, and a liquid introduction connector (connector part 36) that communicates with the liquid reservoir part 50 and is connected to a catheter. The housing portion 10 includes a metal member 90, and the port detection device 200 includes a detection unit 230 that detects generation of an eddy current in the metal member 90 of the liquid injection port 100.

Port detection device 200 is a well-known metal detector that detects metal using electromagnetic induction. According to this embodiment, the position of the liquid injection port 100 can be detected by detecting the metal member 90 with the port detection device 200. Therefore, it becomes possible to recognize the position of the liquid injection port 100 from outside the body.

Further, as shown in any of FIGS. 1 to 3, the liquid injection port 100 according to the present embodiment is the liquid injection port 100 in the liquid injection port system 300 of the present embodiment, and is a liquid injection port 100 in the liquid injection port system 300 of the present embodiment. The housing part 10 has a concave part constituting a liquid reservoir part 50 for temporarily storing liquid, a plug body 20 that closes the upper opening (opening 56) of the concave part, and a housing part 10 that communicates with the liquid reservoir part 50 and is connected to a catheter. The housing part 10 includes a metal member 90.

The liquid injection port 100 is placed in a subcutaneously implanted state in the subject. The liquid injection port 100 includes a housing portion 10, a liquid reservoir portion 50, a connector portion 36, a plurality of rigid frames (an upper frame 60 and a lower frame 70), and a plug body 20.
The liquid reservoir part 50 is included in the housing part 10. The liquid reservoir 50 has an opening 56 and stores liquid.
The connector portion 36 communicates with the outside of the housing portion 10 from the liquid reservoir portion 50 .
The upper frame 60 and the lower frame 70 have higher rigidity than the housing part 10, and are combined with each other to form an annular frame.
The plug body 20 is also referred to as a diaphragm, and is made of an elastic body. The plug 20 is pushed into the frame and covers the opening 56.

The plurality of rigid frames include an annular upper frame 60 located above and an annular lower frame 70 located below.
Here, the upper and lower sides refer to the top side (upper side in FIG. 3) and the bottom side (lower side in FIG. 3) of the liquid injection port 100. Furthermore, when viewed from above or below, an annular shape is defined as a shape that surrounds a certain area (circle, square, etc.), or a shape that surrounds a certain area with a part of its outline missing (C-shape). or U-shape, etc.).
The upper frame 60 has a cylindrical portion formed in a cylindrical shape with a small dimension in the axial direction (vertical dimension), and an inner flange portion that projects inward from the upper end of the cylindrical portion.
The lower frame 70 has a cylindrical portion formed in a cylindrical shape with a small dimension in the axial direction (vertical dimension), and an inner flange portion projecting inward from the lower end of the cylindrical portion.
For example, the inner diameter of the cylindrical portion of the upper frame 60 and the outer diameter of the cylindrical portion of the lower frame 70 are set to be equal to each other, and the cylindrical portion of the lower frame 70 is placed within the cylindrical portion of the upper frame 60. It is embedded.
The inner flange portion of the upper frame 60 and the inner flange portion of the lower frame 70 are opposed to each other. The inner flange portion of the upper frame 60 and the inner flange portion of the lower frame 70 sandwich the plug body 20 from above and below, thereby applying a pressing force to the plug body 20.
Upper frame 60 and lower frame 70 are preferably formed from a highly rigid material. Examples of the material include metals such as titanium and stainless steel. Note that the upper frame 60 and the lower frame 70 are not limited to being made of a single material, but may be made of multiple types of materials.
In this embodiment, the annular frame into which the plug 20 is press-fitted is composed of two rigid frames, an upper frame 60 and a lower frame 70, and applies a pressing force to the plug 20 from above and below. , this aspect is just an example, and is not necessarily limited to this aspect. For example, an annular frame may be configured with three or more rigid frames, or a plurality of arc-shaped rigid frames may be combined to apply a pressing force from the side.

For example, the inner diameter of the inner flange of the upper frame 60 is equal to the inner diameter of the inner flange of the lower frame 70. Thereby, when the puncture needle (not shown) is inserted into the plug body 20, it is possible to suppress the puncture needle from colliding with the inner flange portion of the lower frame 70. However, this aspect is just an example, and even if the inner diameter of the inner flange portion of the upper frame 60 is smaller than the inner diameter of the inner flange portion of the lower frame 70, the same effect can be achieved.

The plug 20 is a member that covers the opening 56 of the liquid reservoir 50, and is made of an elastic material that can be pierced with a puncture needle (not shown). Furthermore, a strong pressing force is applied to the plug body 20 by the upper frame 60 and the lower frame 70, so that the hole created when the puncture needle is removed is naturally closed. Examples of the material for forming the plug body 20 include rubbers such as silicone, isoprene, and latex.

Preferably, the plug body 20 is integrally molded with the upper frame 60 or the lower frame 70. Thereby, even when a strong pressing force is applied, the plug body 20 can be made difficult to peel off from the frame body.
As an example, the plug body 20 is integrally molded with the lower frame 70. More specifically, the inner flange portion of the lower frame 70 is provided with a plurality of small holes having a diameter smaller than the width of the inner flange portion, and the plug body 20 is inserted into the upper portion of the inner flange portion through these small holes. and are interconnected below, thereby being integrated with the lower frame 70.
When the plug body 20 is integrally molded with the lower frame 70, the annular convex portion 28 and the annular recess portion 26, which are part of the plug body 20, are formed below the lower surface of the inner flange portion.
The plug body 20 has a puncture section upper surface 22 and a puncture lower surface 24. The puncture lower surface 24 protrudes below, for example, more than the recess 26 and the projection 28.
The annular convex portion 28 is formed on the lower surface of the plug body 20 and is made of one material with the plug body 20, and is in contact with the periphery of the opening 56 of the liquid reservoir portion 50. The annular convex portion 28 acts like a so-called O-ring, and prevents the liquid stored in the liquid reservoir 50 from leaking from the opening 56. It is desirable that the annular convex portion 28 extends in all directions around the central axis of the lower frame 70 and is formed in a closed annular shape with no missing portion.
Note that the present invention is not limited to the aspect in which the plug body 20 and the annular convex portion 28 are integrally molded, and instead of the convex portion 28, an O-ring formed of a separate member from the plug body 20 is used. 20 may be provided.

The housing part 10 includes a lid part 12 located above and a bottom part 14 located below. The lid portion 12 and the bottom portion 14 are made of, for example, a resin material. The housing part 10 is constructed by assembling the lid part 12 and the bottom part 14 together.
The liquid reservoir part 50 is included in the housing part 10, has an opening 56, and stores liquid. With the puncture needle reaching the liquid reservoir 50 via the stopper 20, a liquid such as a medicinal solution is supplied to the liquid reservoir 50 through the puncture needle. Note that examples of the liquid medicine include anticancer drugs and nutritional supplements. The connector portion 36 communicates with the outside of the housing portion 10 from the liquid reservoir portion 50 .

The lid portion 12 is formed with an opening 12a for inserting a puncture needle into the plug body 20 from the outside.
As shown in FIG. 3, for example, the inner diameter of the opening 12a is set to be equal to the inner diameter of the inner flange portion of the upper frame 60. Hereinafter, the inner diameter of the opening 12a or the inner diameter of the inner flange portion of the upper frame 60 will be referred to as the puncture opening diameter D1 (FIGS. 2 and 3). The upper part of the plug body 20 is disposed across the inner region of the inner flange portion of the upper frame 60 and the inner region of the opening 12 a of the lid portion 12 .

The liquid reservoir 50 is a part that stores liquid such as a medicinal solution injected through a puncture needle (not shown) inserted into the stopper 20.
The liquid reservoir portion 50 is constituted by a recess formed in the bottom portion 14. Therefore, the bottom surface 52 of the liquid reservoir 50 is made of a resin material, and the side surfaces 54 thereof are also made of a resin material. That is, the wall surfaces (bottom surface 52 and side surfaces 54) surrounding the liquid reservoir portion 50 are formed of a resin material.
Note that the present invention is not limited to this example, and the liquid reservoir portion 50 may be constituted by a separate member from the bottom portion 14. In this case, the liquid reservoir portion 50 may be made of a resin material, or may be made of another material. Further, the liquid reservoir portion 50 may be formed by a portion of the lower frame 70.
For example, in the bottom portion 14, a portion around the opening 56 of the liquid reservoir portion 50 is an annular convex portion that projects upward. Furthermore, as described above, the annular recess 26 is adjacent to the annular protrusion 28 on the lower surface of the plug body 20 . The annular convex portion around the opening 56 in the bottom portion 14 fits into the annular recess 26 . Thereby, the peripheral edge of the opening 56 together with the annular convex portion 28 functions as a so-called O-ring, and liquid leakage from the opening 56 can be suppressed more reliably.
In this embodiment, the annular recess 26 is formed on the inner diameter side of the annular protrusion 28, but the annular recess 26 is formed on the outer diameter side of the annular protrusion 28. The same effect can be achieved even in the mode in which this is done.

The housing part 10 is a part that accommodates and protects other components.
The housing portion 10 is made of, for example, a resin material. As mentioned above, the housing portion 10 includes an upper lid portion 12 and a lower bottom portion 14.
As shown in FIG. 3, the upper frame 60 and the lower frame 70 are sandwiched between the lid part 12 and the bottom part 14 from above and below. Note that the pressing force applied by the lid part 12 and the bottom part 14 to the upper frame 60 and the lower frame 70 is equal to the pressing force applied to the plug body 20 by the inner flange part of the upper frame 60 and the inner flange part of the lower frame 70. It is less than the pressure.
The pressing force exerted by the lid portion 12 and the bottom portion 14 on the upper frame 60 and the lower frame 70 is also transmitted to the locations where the annular protrusion 28 and the annular recess 26 come into contact. Therefore, the liquid tightness at the location is improved.

Since the housing portion 10 comes into contact with living tissue, it is preferably biocompatible. Further, since the liquid injection port 100 is buried under the skin for a long period of time, it is preferable that the housing portion 10 has a certain strength and does not deform due to body heat. Further, it is preferable that the housing portion 10 is formed of a material that is easy to process.
Examples of materials that meet the above conditions include polyether sulfone resin, polyurethane resin, polypropylene resin, and polyethylene terephthalate resin.

The connector portion 36 functions as a flow path for discharging the liquid stored in the liquid reservoir portion 50 to the outside of the liquid injection port 100, more specifically to a catheter (not shown) connected to the tip of the connector portion 36. It is a member.
The base end of the connector portion 36 is fitted into a communication hole 58 provided in the side surface 54 of the liquid reservoir portion 50, as shown in FIG. The inner diameter of the connector portion 36 and the inner diameter of the communication hole 58 are approximately equal, so that the liquid stored in the liquid reservoir portion 50 flows smoothly to the connector portion 36 via the communication hole 58. .
Since the connector portion 36 serves as a liquid flow path, it is preferably formed of a chemical-resistant material. Furthermore, since a long catheter (not shown) is connected and the load applied to the catheter is also applied to the connector part 36, it is desirable that the connector part 36 has a certain level of strength (rigidity).
Examples of the material constituting the connector portion 36 include metals such as titanium and stainless steel, hard resin materials, and ceramics.
The shape of the outer circumferential surface of the connector portion 36 includes a tapered portion that expands from the distal end to the proximal end, and the outer diameter decreases discontinuously (steeply) at the proximal end of the tapered portion. ing. For this reason, the catheter (not shown) fitted into the connector part 36 (fitted externally) is prevented from falling off from the connector part 36.

Liquid injection port 100 further includes a lock base 34 and a lock top 32.
The lock base portion 34 is provided so as to surround the periphery of the connector portion 36. A catheter (not shown) connected to the distal end of the connector portion 36 is fitted into a groove formed by the lock base 34 and the connector portion 36.
It is desirable that the lock base portion 34 has the same strength (rigidity) as the connector portion 36. Therefore, examples of the material for forming the lock base 34 include metals such as titanium and stainless steel, hard resin materials, and ceramics.

The lock top 32 is provided to enclose the connector portion 36 and the lock base 34, and protects a catheter (not shown) attached to the connector portion 36 and the lock base 34. Since the inner wall surface of the lock top 32 contacts the catheter when the catheter is bent, it is preferable that the inner wall surface has appropriate flexibility. Therefore, examples of the material for forming the lock top 32 include rubbers such as silicone, isoprene, and latex.

Port detection device 200 forms an electromagnetic field around port detection device 200 . The detection unit 230 determines whether the electromagnetic field is distorted based on the occurrence of an eddy current in the metal member 90 of the liquid injection port 100, and detects whether the metal member 90 is present at a short distance. do.
The port detection device 200 includes, for example, a primary coil that forms an electromagnetic field and a secondary coil that generates an induced current based on the generation of an eddy current in the metal member 90. The port detection device 200 further includes, for example, a current detection section that detects an induced current generated in the secondary coil.

The metal material constituting the metal member 90 is not particularly limited as long as it is a metal. As an example, the metal member 90 is made of titanium, stainless steel, or the like.

The shape of the metal member 90 is not particularly limited, but as an example, as shown in FIG. 2, it may be formed in an annular shape surrounding the opening 12a. In this case, the inner diameter D2 (FIGS. 2 and 3) of the metal member 90 is preferably as close to the puncture opening diameter D1 as possible. The inner diameter D2 is preferably +30% or less with respect to the puncture opening diameter D1, more preferably +20% or less with respect to the puncture opening diameter D1, and should be +10% or less with respect to the puncture opening diameter D1. is more preferable.
As an example, the metal member 90 has a flat shape with a thin thickness (vertical dimension).

In the case of this embodiment, as shown in FIGS. 2 and 3, in the metal member 90, each of the plurality of portions distributed and arranged so as to surround the center of the plug body 20 in a plan view is different from other portions. The thick portion 91 is formed thicker than the other.
The magnitude of the eddy current generated in each part of the metal member 90 by the electromagnetic field generated by the port detection device 200 increases according to the thickness of each part, so the port detection device 200 is scanned along the body surface of the subject and detected. The center position of the stopper 20 can be recognized by determining a plurality of locations (locations corresponding to the thick portion 91) where the eddy current increases. Furthermore, the detection accuracy of the port detection device 200 can be improved while suppressing an increase in the planar dimensions of the liquid injection port 100.

In the case of this embodiment, the thick portions 91 are arranged at three or more locations in the circumferential direction of the metal member 90 (for example, three locations as shown in FIG. 2). Moreover, it is preferable that the plurality of thick parts 91 are arranged at equal angular intervals in the circumferential direction of the metal member 90.
The thick portion 91 is preferably a portion of the metal member 90 that partially protrudes upward (rather than downward). Since the thick portion 91 protrudes upward, that is, toward the body surface side, the detection accuracy of the thick portion 91 by the port detection device 200 is further improved.

Note that the present invention is not limited to this example. In the metal member 90, each of the plurality of portions distributed in a manner surrounding the center of the plug body 20 in a plan view is wider than other portions ( For example, it is also preferable that the plug body 20 has a wide portion formed to be wide in the radial direction.
The magnitude of the eddy current generated in each part of the metal member 90 by the electromagnetic field generated by the port detection device 200 increases according to the area of each part. The center position of the plug body 20 can be recognized by determining a plurality of locations (locations corresponding to the wide portions) where the eddy current is large.

It is preferable that the metal member 90 is disposed above the plug body 20. In the case of this embodiment, the metal member 90 is disposed above the portion of the stopper 20 located outside the opening 12a in plan view.
This allows the metal member 90 to be located closer to the body surface, thereby improving the detection accuracy of the metal member 90 by the port detection device 200.
The metal member 90 is, for example, embedded in the lid portion 12.

As described above, in the case of this embodiment, the liquid injection port 100 further includes a metal frame (for example, composed of the upper frame 60 and the lower frame 70) holding the stopper 20. There is. As shown in FIG. 3, the thickness of the metal member 90 is greater than the thickness of the frame.
Preferably, the minimum thickness of the metal member 90 is greater than the maximum thickness of the frame. As a result, the port detection device 200 performs a detection operation mainly based on the eddy current generated in the metal member 90, so that the detection accuracy of the metal member 90 by the port detection device 200 is further improved.

Here, depending on the type of metal, the induced current exhibits a specific phase angle. Therefore, it is also possible to selectively detect a specific metal by removing the phase angle of a type of metal that does not need to be detected. Therefore, by using different materials for the metal material forming the frame (upper frame 60, lower frame 70) and the metal member forming the metal member 90, it is possible to selectively detect the metal member 90. becomes.

[Second embodiment]
Next, a second embodiment will be described using FIG. 5.
The liquid injection port 100 according to the present embodiment is different from the liquid injection port 100 according to the first embodiment described above in the points described below. It is configured similarly to injection port 100.

As shown in FIG. 5, in the case of this embodiment, the housing part 10 includes a plurality of metal members 90, and these metal members 90 are distributed and arranged so as to surround the center of the plug body 20 in a plan view. ing.
According to this embodiment, by scanning the port detection device 200 along the body surface of the subject and determining a plurality of locations (locations corresponding to each metal member 90) where the detected eddy current becomes large, the plug is detected. 20 center positions can be recognized.

In the case of this embodiment, the metal members 90 are arranged at three or more locations (for example, five locations as shown in FIG. 2) in the circumferential direction of the plug body 20. Moreover, it is preferable that the plurality of metal members 90 are arranged at equal angular intervals in the circumferential direction of the plug body 20.

The present invention is not limited to the above-described embodiments, but also includes various modifications and improvements as long as the object of the present invention is achieved.
Furthermore, the above-described embodiments can be combined as appropriate without departing from the spirit of the present invention.

This embodiment includes the following technical ideas.
(1) A liquid injection port that is implanted in the body,
a port detection device for detecting the position of the liquid injection port;
A liquid injection port system comprising:
The liquid injection port is
a housing portion having a recess that forms a liquid reservoir for temporarily storing liquid supplied from outside the body;
a plug blocking the upper opening of the recess;
a liquid introduction connector that communicates with the liquid reservoir and is connected to the catheter;
Equipped with
The housing portion includes a metal member,
The port detection device is a liquid injection port system including a detection section that detects generation of an eddy current in the metal member of the liquid injection port.
(2) The liquid injection port in the liquid injection port system according to (1),
a housing portion having a recess that forms a liquid reservoir for temporarily storing liquid supplied from outside the body;
a plug blocking the upper opening of the recess;
a liquid introduction connector that communicates with the liquid reservoir and is connected to the catheter;
Equipped with
The housing portion includes a liquid injection port including a metal member.
(3) In the metal member, each of the plurality of portions distributed in a manner surrounding the center of the plug in a plan view is a thick wall portion that is thicker than other portions. The liquid injection port described in (2).
(4) The liquid injection port according to (2), wherein the housing portion includes a plurality of the metal members, and these metal members are distributed and arranged so as to surround the center of the plug body in a plan view. .
(5) The liquid injection port according to any one of (2) to (4), wherein the metal member is arranged above the plug body.
(6) further comprising a metal frame holding the stopper;
The liquid injection port according to any one of (2) to (5), wherein the thickness of the metal member is larger than the thickness of the frame.

10 Housing section 12 Lid section 12a Opening 14 Bottom section 20 Plug body 22 Puncture section top surface 24 Puncture bottom surface 26 Recess section 28 Convex section 32 Lock top 34 Lock base section 36 Connector section 50 Liquid reservoir section 52 Bottom surface 54 Side surface 56 Opening 58 Communication hole 60 Upper side Frame 70 Lower frame 90 Metal member 91 Thick wall portion 100 Liquid injection port 200 Port detection device 230 Detection section 300 Liquid injection port system

Claims (5)

a housing portion having a recess that forms a liquid reservoir for temporarily storing liquid supplied from outside the body; a plug that closes an upper opening of the recess; and a plug that communicates with the liquid reservoir and is connected to a catheter. a liquid inlet port that is implanted in the body and includes a liquid introduction connector and a metal member;
a port detection device for detecting the position of the liquid injection port, the port detection device comprising a detection section that detects generation of an eddy current in the metal member of the liquid injection port;
The liquid injection port in a liquid injection port system comprising :
further comprising a metal frame holding the plug,
The thickness of the metal member is larger than the thickness of the frame,
A liquid injection port , wherein the metal member is disposed above the frame . a housing portion having a recess that forms a liquid reservoir for temporarily storing liquid supplied from outside the body; a plug that closes an upper opening of the recess; and a plug that communicates with the liquid reservoir and is connected to a catheter. a liquid inlet port that is implanted in the body and includes a liquid introduction connector and a metal member;
a port detection device for detecting the position of the liquid injection port, the port detection device comprising a detection section that detects generation of an eddy current in the metal member of the liquid injection port;
The liquid injection port in a liquid injection port system comprising:
further comprising a metal frame holding the plug,
The metal material constituting the frame and the metal material constituting the metal member are different materials,
A liquid injection port in which a phase angle of the eddy current generated in the frame body and a phase angle of the eddy current generated in the metal member are different from each other. The metal member is formed in an annular shape surrounding the center of the plug body in plan view,
In the metal member, each of the plurality of portions distributed and arranged so as to surround the center of the plug body in a plan view is a thick portion formed to be thicker than other portions ,
The liquid injection port according to claim 1 or 2 , wherein the thick portion is a portion of the metal member that partially projects upward . 3. The liquid injection port according to claim 1 , wherein the housing portion includes a plurality of the metal members, and these metal members are distributed and arranged so as to surround the center of the plug body in a plan view. The liquid injection port according to any one of claims 1 to 4, wherein the metal member is arranged above the plug body.

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