JP7348786B2 - automatic analyzer - Google Patents

Description

The present disclosure relates to an automatic analyzer for, for example, clinical testing.

In recent years, automatic analyzers have been required to have high working efficiency and high reliability, and are becoming more multifunctional and smaller. One way to achieve this is to arrange a plurality of photometers with different sensitivities and measurement items on one cell disk. When arranging multiple photometers, by arranging them as close as possible to each other, reactions can be measured at approximately the same time. Reliability can be further increased by comparing and verifying data from multiple photometers in this state.

However, since the cells of the automatic analyzers currently in use are small, it is often difficult to arrange multiple photometers around them. Therefore, in reality, it is desirable to arrange a plurality of photometers at a distance as close as possible, and if possible, to adjacent cells. However, in this case, if the photometers are placed too close to each other, there is a possibility that the light incident on the cell from each light source will become stray light to the adjacent light receiver. Light incident on a cell is not only scattered by the reaction solution inside the cell and directly incident on an adjacent photoreceptor, but also may be incident on an adjacent cell and then incident on an adjacent photoreceptor due to scattering. .

One possible method for avoiding stray light from adjacent light sources is to shield the sides of the cell from light. As a method for shielding the side surfaces of a cell from light, a method for manufacturing an optical analysis cell in which black quartz glass and transparent quartz glass are combined is known (see, for example, Patent Document 1). Another possible method is to shield the sides from light by coating or painting.

JP2006-27930A

Using the conventional method described above, it is possible to block light that enters adjacent cells from the side of the cell, but scattered light passes through the transparent surface and strays into adjacent cells or the receiver of an adjacent photometer. There is still a risk of entering as

In automatic analyzers for clinical tests, attempts have been made to improve sensitivity by measuring the amount of scattered light instead of measuring the amount of transmitted light with a photometer. For example, in a reagent that utilizes an antigen-antibody reaction, an antigen contained in a sample is reacted with an antibody contained in the reagent. An antigen-antibody reaction product is created, the particles are irradiated with light, and the magnitude of the scattered or transmitted light is measured. Such scattering photometers measure high sensitivity by measuring minute changes in scattered light. Therefore, stray light that passes through the light-transmitting surface and enters may have a large effect on increasing sensitivity.

In view of this situation, the present disclosure provides that when a plurality of photometers are arranged on one cell disk in an automatic analyzer, light irradiated to the cell from one photometer light source is scattered within the cell, Provides a technique for preventing light from entering the light receivers of adjacent cells (cells placed close to each other) or adjacent photometers (photometers placed close to each other).

In order to solve the above problems, the present disclosure provides a cell disk in which a plurality of cells for reacting a sample and a reagent are mounted in an annular shape, a first light source and a second light source that irradiate the cells with light, and a first light source and a second light source that irradiate the cells with light. A first light receiver that detects the light emitted from the light source, a second light receiver that detects the light emitted from the second light source, and is arranged between each of the plurality of cells, and the width dimension of the side surface of the cell is a plurality of light shielding plates having a wide width, the plurality of light shielding plates allow the light emitted from the first light source to enter the second light receiver, and the light emitted from the second light source to enter the first light receiver. We propose an automated analyzer configured to prevent

Further features related to the present disclosure will become apparent from the description herein and the accompanying drawings. Aspects of the present disclosure may also be realized and realized by means of the elements and combinations of various elements and aspects of the following detailed description and appended claims.
It should be understood that the description herein is merely a typical example and does not limit the scope of the claims or applications of the present disclosure in any way.

According to the technology of the present disclosure, it is possible to realize an automatic analyzer in which a plurality of photometers are provided in one cell disk, each photometer is placed in a close position, and each photometer is not affected by stray light. It becomes possible.

1 is a diagram illustrating an overall schematic configuration example of an automatic analyzer 100 commonly used in each embodiment. FIG. 3 is a schematic diagram showing the arrangement relationship between a light shielding plate 17 and a cell 8 in the first embodiment. FIG. 2 is a plan view of a general arrangement example of a plurality of photometers. FIG. 3 is a plan view showing an example of arrangement of a plurality of measurement units in the first embodiment. FIG. 7 is a schematic diagram showing an example of the arrangement relationship between a light shielding plate 17 and a cell 8 in a second embodiment. 7 is a diagram for explaining the technical effect obtained by bringing the scattered light receiver 21 closer to the cell 8. FIG. FIG. 7 is a schematic diagram showing an example of the arrangement relationship between a light shielding plate 17 and a cell 8 in a third embodiment. 7 is a diagram for explaining the technical effect obtained by bringing the light source 18 closer to the cell 8. FIG. FIG. 7 is a plan view showing the inside of the cell disk 9 when the light shielding plate 17 is arranged diagonally. It is a figure which shows the example of a schematic structure of the continuous cell 108 and the light-shielding plate unit 117 by 5th Embodiment.

Embodiments will be described below with reference to the accompanying drawings. In the accompanying drawings, functionally similar elements may be designated by the same number. Note that although the attached drawings show specific embodiments and implementation examples in accordance with the principles of the present disclosure, they are for the purpose of understanding the present disclosure, and are not intended to be construed as limiting the present disclosure in any way. It is not used.

Although the embodiments are described in sufficient detail for those skilled in the art to implement the present disclosure, other implementations and forms are possible without departing from the scope and spirit of the technical idea of the present disclosure. It is necessary to understand that it is possible to change the composition and structure and replace various elements. Therefore, the following description should not be interpreted as being limited to this.

(1) First embodiment <Example of overall configuration of automatic analyzer>
FIG. 1 is a diagram showing an overall schematic configuration example of an automatic analyzer 100 commonly used in each embodiment.

The automatic analyzer 100 mainly includes (i) three types of disks: a sample disk 3, a reagent disk 6, and a cell disk 9, and (ii) a sample dispensing mechanism 10 that moves samples and reagents between these disks. a reagent dispensing mechanism 11; (iii) a control circuit 101 that controls the operations of the sample dispensing mechanism 10 and the reagent dispensing mechanism 11; (iv) a transmitted light measurement circuit 102 that measures transmitted light; and (v) a scattering A scattered light measurement circuit 103 that measures light; (vi) an analysis unit 1041 that analyzes data measured by the transmitted light measurement circuit 102 and the scattered light measurement circuit 103; and (vii) that stores control data, measurement data, and analysis data. (viii) an input unit (input device: keyboard, mouse, various switches, microphone, scanner, etc.) 105 for inputting data to the data storage unit 1042; (ix) It includes an output unit (output device: display, printer, speaker, etc.) 106 that acquires data from the data storage unit 1042 and outputs it.

A plurality of sample cups 2 containing samples 1 are arranged on the circumference of the sample disk 3. A plurality of reagent bottles 5 containing reagents 4 are arranged on the reagent disk 6. A plurality of cells 8 are arranged around the circumference of the cell disk 9, in which the sample 1 and the reagent 4 are mixed to form a reaction liquid 7.

The sample dispensing mechanism 10 moves a certain amount of the sample 1 from the sample cup 2 to the cell 8. The reagent dispensing mechanism 11 moves a certain amount of the reagent 4 from the reagent bottle 5 to the cell 8 . The stirring unit 12 stirs and mixes the sample 1 and the reagent 4 within the cell 8 . The cleaning section (cleaning mechanism) 14 discharges the reaction liquid 7 from the cell 8 after the analysis and cleans it. The next sample 1 is again dispensed from the sample dispensing mechanism 10 into the cleaned cell 8, and a new reagent 4 is dispensed from the reagent dispensing mechanism 11, and used for another reaction.

The cell 8 is immersed in a constant temperature fluid 15 in a constant temperature bath whose temperature and flow rate are controlled, and the cell 8 and the reaction liquid 7 therein are moved while being kept at a constant temperature. Water is used as the constant temperature fluid 15, and the temperature and flow rate of the constant temperature fluid are controlled by a constant temperature fluid control section (not shown). The temperature of the constant temperature fluid 15 is controlled to 37±0.1° C., which is the reaction temperature.

A transmitted light measuring section 13 and a scattered light measuring section 16 are installed on a part of the circumference of the cell disk. The transmitted light measuring section 13 and the scattered light measuring section 16 irradiate the reaction liquid in the cell with light from a light source and measure the light after interacting with the reaction liquid.

The transmitted light measuring section 13 irradiates the moving cell 8 with light from a halogen lamp light source, spectrally spectra the transmitted light using a diffraction grating, and then receives the light with a photodiode array in which photodiodes are arranged in an array. The wavelengths to be received are, for example, 340 nm, 405 nm, 450 nm, 480 nm, 505 nm, 546 nm, 570 nm, 600 nm, 660 nm, 700 nm, 750 nm, and 800 nm. The transmitted light measurement unit 13 sends transmitted light amount data (converted to the amount of current or voltage) received by the light receiver to the data storage unit 1042 in the PC via the transmitted light measurement circuit 102.

The scattered light measuring section 16 can use, for example, an LED light source as a light source, and irradiates the moving cell 8 with irradiation light from the LED light source, and receives transmitted light with a transmitted light receiver. In the case of an LED light source, for example, 700 nm can be used as the irradiation light wavelength. In each embodiment, an LED is used as a light source, but a laser, a xenon lamp, or a halogen lamp may also be used. The scattered light measurement unit 16 measures scattered light in directions 20° and 30° away from the optical axis in the air using scattered light receivers, and calculates scattered light amount data (current amount) incident on the light receivers. (converted into an amount of voltage) is sent to the data storage unit 1042 in the PC through the scattered light measurement circuit 103.

The concentration determination of a certain measurement substance in sample 1 is performed in the following procedure. That is, first, the sample dispensing mechanism 10 dispenses a certain amount of the sample 1 in the sample cup 2 into the cell. Next, the reagent dispensing mechanism 11 dispenses a fixed amount of the reagent 4 in the reagent bottle 5 into the cell. During these dispensing operations, the sample disk 3, reagent disk 6, and cell disk 9 are rotationally driven by respective drive units (not shown) under the control of the control circuit 101. The sample cup 2, reagent bottle 5, and cell 8 are moved in accordance with the timing of the sample dispensing mechanism 10 or the reagent dispensing mechanism 11. Subsequently, the stirring unit 12 stirs the sample 1 and the reagent 4 in the cell 8 to form a reaction liquid 7. The transmitted light and scattered light from the reaction liquid 7 are measured each time the cell disk 9 passes through the measurement positions of the transmitted light measuring section 13 and the scattered light measuring section 16 while the cell disk 9 is rotating. Each measurement data is sequentially stored in the data storage unit 1042 as reaction process data via the transmitted light measurement circuit 102 or the scattered light measurement circuit 103. After measurement for a certain period of time, for example about 10 minutes, the cleaning section (cleaning mechanism) 14 cleans the inside of the cell 8, and the next test item is analyzed. During this time, if necessary, another reagent 4 is additionally dispensed into the cell by the reagent dispensing mechanism 11, stirred by the stirring section 12, and further measured for a certain period of time. As a result, reaction process data of the reaction liquid 7 having a fixed time interval is stored in the data storage section 1042. From the stored reaction process data for each light reception angle of the scattered light measurement unit 16, the analysis unit 1041 determines the change in light amount due to the reaction over a certain period of time. Then, a quantitative result is calculated based on the calibration curve data stored in advance in the data storage unit 1042, and output (displayed) from the output unit 106. Data necessary for controlling and analyzing each section is input from the input section 105 to the data storage section 1042. Further, data, results, alarms, etc. in various storage units are outputted (displayed, etc.) by the output unit 106.

<Arrangement relationship between light shielding plate and cell>
FIG. 2 is a schematic diagram showing the arrangement relationship between the light shielding plate 17 and the cells 8 in the first embodiment. Each cell 8 is separated by a light shielding plate 17. The light shielding plate 17 has a height that is higher than the height of the reaction liquid 7 held in the cell 8 and a width that is larger than the width of the side surface of the cell 8 . This prevents light scattered within one cell 8 from passing through the side surface and transparent surface of the cell 8 and entering another adjacent (nearly placed) cell 8 or a light receiver, resulting in stray light. becomes possible.

<Technical effect>
The technical effects obtained by configuring the width of the light shielding plate 17 to be larger than the side width of the cell 8 will be described with reference to FIGS. 3 and 4. FIG. 3 is a plan view of a typical arrangement of multiple photometers. FIG. 4 is a plan view showing an example of arrangement of a plurality of measurement units in the first embodiment.

A portion of the light irradiated onto the cell 8 from the light sources 18 and 20 is scattered forward and backward. When the width of the light shielding plate 17 is the same as or smaller than the width of the side surface of the cell 8, the scattered light is transmitted to the adjacent transmitted light receiver 19 and scattered light receiver as forward scattered light 24, as shown in FIG. 21 and enters the adjacent cell 8 as backscattered light 25. These forward scattered light 24 and backward scattered light 25 may become stray light.

Therefore, as shown in FIG. 4, a light shielding plate 17 that is wider than the width of the side surface of the cell 8 (for example, it can have a width three times as wide as the width of the side surface of the cell 8) is arranged. This can prevent stray light from entering the adjacent transmitted light receiver 19, scattered light receiver 21, and cell 8. In FIG. 4, the light shielding plate 17 is configured to be larger than the side surface of the cell 8 on both sides of the light sources 18 and 20 and the transmitted light receiver 19 and scattered light receiver 21. (a configuration in which the light beams protrude from both sides of the transmitted light receiver 19 and the scattered light receiver 21). However, if there is no problem in detection, the light shielding plate 17 is configured to be larger than the side surface of the cell 8 on either the light sources 18 and 20 side or the transmitted light receiver 19 and scattered light receiver 21 side (transmitted light It may also be configured such that it protrudes from either the light receiver 19 or the scattered light receiver 21 side. If the dimensions of the light sources 18 and 20 are large, the forward scattered light 24 becomes stray light. If the dimensions of the transmitted light receiver 19 and the scattered light receiver 21 are large, the backscattered light 25 becomes stray light.

Regarding the protrusion size of the light shielding plate 17 from both ends of the cell 8, the protrusion size toward the light sources 18 and 20 side and the protrusion size toward the transmitted light receiver 19 and scattered light receiver 21 side are made to be approximately the same. Alternatively, one of the protrusion sizes may be larger than the other protrusion size.

(2) Second Embodiment In the second embodiment, the light shielding plate 17 is arranged to protrude (protrude) toward the light source side with respect to the cell 8, and the transmitted light receiver 19 and the scattered light receiver on the opposite side are arranged. A method of improving the performance of the transmitted light measuring section 13 and the scattered light measuring section 16 while improving the light blocking performance by arranging the light transmitting section 21 close to the cell 8 will be described. The other device configurations are the same as in the first embodiment.

<Arrangement relationship between light shielding plate and cell>
FIG. 5 is a schematic diagram showing an example of the arrangement relationship between the light shielding plate 17 and the cells 8 in the second embodiment. As shown in FIG. 5, the light shielding plate 17 is configured to protrude (protrude) only toward the light sources 18 and 20. In this case, the light shielding plate 17 does not protrude (does not protrude) toward the transmitted light receiver 19 and scattered light receiver 21 side of the cell 8 . Therefore, by providing the cutout portion 41 in the cell disk 9, the transmitted light receiver 19 and the scattered light receiver 21 can be brought closer to the cell 8. That is, the transmitted light receiver 19 and the scattered light receiver 21 are arranged in the cutout 41 . As a result, the distance from the transmitted light receiver 19 and the scattered light receiver 21 to one end of the cell 8 is shorter than the distance from the light sources 18 and 20 to the other end of the cell 8. can do.

<Technical effects when placing the scattered light receiver close to the cell>
FIG. 6 is a diagram for explaining the technical effect obtained by bringing the scattered light receiver 21 close to the cell 8, and shows an example of a schematic internal configuration of the scattered light measuring section 16.

In the scattered light measurement unit 16, the transmitted light of the light irradiated from the light source 20 to the cell 8 is received by the transmitted light receiver 211, and the scattered light is received by the scattered light receivers provided in the directions of 20° and 30°. Light is received at 212 and 213. At this time, the shape of the scattered light receiver 21 when placed close to the cell 8 (in the case of the configuration shown in FIG. 5) is expressed by reference numeral 26. Further, the shape of the scattered light receiver 21 when placed at a position far from the cell 8 is expressed by reference numeral 27. As can be seen from FIG. 6, by arranging the scattered light receiver 21 at a position close to the cell 8, the overall shape (size) of the scattered light receiver 21 can be reduced, and the device (automatic analyzer 100) It becomes possible to reduce the size of the device without changing the processing capacity of the device.

(3) Third Embodiment In the third embodiment, the light shielding plate 17 is arranged to protrude (protrude) from the cell 8 toward the receiver side, and the light sources 18 and 20 on the opposite side are brought closer to the cell. A method of improving the performance of the transmitted light measurement unit 13 and the scattered light measurement unit 16 while improving the light blocking performance by arranging the light shielding units will be described. The other device configurations are the same as in the first embodiment.

<Arrangement relationship between light shielding plate and cell>
FIG. 7 is a schematic diagram showing an example of the arrangement relationship between the light shielding plate 17 and the cells 8 in the third embodiment. As shown in FIG. 7, the light shielding plate 17 is configured to protrude (protrude) toward the transmitted light receiver 19 and scattered light receiver 21 side. In this case, the light shielding plate 17 does not protrude toward the light sources 18 and 20 of the cell 8. Therefore, by providing the cutout portion 42 in the cell disk 9, the light sources 18 and 20 can be brought closer to the cell 8. That is, the light sources 18 and 20 are placed in the cutout 42 . As a result, the distance from the light sources 18 and 20 to one end of the cell 8 is shorter than the distance from the transmitted light receiver 19 and the scattered light receiver 21 to the other end of the cell 8. can do.

<Technical effect when bringing the light source closer to the cell>
FIG. 8 is a diagram for explaining the technical effect obtained by bringing the light source 18 closer to the cell 8, and shows an example of a schematic internal configuration of the transmitted light measuring section 13.

In the optical system of the transmitted light measurement unit 13, light emitted from the light source 18 passes through the entrance slit 28 and is irradiated onto the cell 8. The transmitted light 23 that has passed through the cell 8 and the light receiving slit 29 is received (detected) by the transmitted light receiver 19 .

8(a) is a diagram when the entrance slit 28 is arranged near the cell 8 (this embodiment), and FIG. 8(b) is a diagram when the entrance slit 28 is arranged far from the cell 8. It is. In FIG. 8(b), since the light passing through the entrance slit 28 hits the cell bottom and the reaction liquid surface, the light reflected from these surfaces passes through the light receiving slit 29 and enters the detection section (transmitted light receiver 19). There is a risk of In the case of FIG. 8(b), in order to avoid this danger, it is necessary to raise the optical axis 30 and the reaction liquid level 31, which increases the amount of reaction liquid required for measurement.

On the other hand, by arranging the entrance slit 28 near the cell 8 as shown in FIG. 8(a), it is possible to perform measurements with a smaller amount of reaction liquid while preventing stray light due to reflection from the cell bottom and the reaction liquid surface 31. becomes possible.

(4) Fourth Embodiment In the fourth embodiment, by arranging the light shielding plate 17 having a width larger than the cell 8 diagonally with respect to the cell 8, the constant temperature fluid 15 contained in the cell disk 9 can be A method for improving the temperature control performance of the cell 8 and reaction liquid is disclosed.

FIG. 9 is a plan view showing the inside of the cell disk 9 when the light shielding plate 17 is arranged diagonally. For example, water is used as the constant temperature fluid 15. Further, it is assumed that the cell disk 9, the cell 8, and the light shielding plate 17 rotate counterclockwise during the measurement. Furthermore, a case is assumed in which the light shielding plate 17 protrudes to the outside of the cell 8 (a protruding configuration). Other device configurations are similar to other embodiments.

When the cell disk 9 rotates counterclockwise, the flow 32 of the constant temperature fluid 15 flowing outside the cells 8 impinges on the light shielding plate 17, passes between the cells, and heads inward. At this time, by tilting the light shielding plate 17 with respect to the rotation direction, it is possible to guide the constant temperature fluid 15 so that it is easier to direct the constant temperature fluid 15 between the cells 8, thereby improving the temperature control performance of the cells 8 and the reaction liquid. (The temperature of the reaction solution can be made uniform).

Note that also in the fourth embodiment, the width of the light shielding plate 17 is configured to be larger than the width of the side surface of the cell 8, so it is possible to expect the technical effects described in the first embodiment. It is.

(5) Fifth Embodiment The fifth embodiment includes a series of cells 108 and a light-shielding plate unit (continuous light-shielding plate) in which a plurality of light-shielding plates 17 are made detachable from the series of cells to improve workability. The configuration of 117 will be disclosed. FIG. 10 is a diagram showing a schematic configuration example of the connected cells 108 and the light shielding plate unit 117 according to the fifth embodiment.

As shown in FIG. 10, the continuous cell 108 has a structure in which a plurality of cells 8 are connected at the upper part. Similarly, the light shielding plate unit 117 also has a continuous light shielding plate shape in which a plurality of light shielding plates 17 are connected. The light shielding plate unit 117 and the continuous cell 108 have a structure that can be attached and detached by inserting each cell 8 between each light shielding plate 17. Further, the relationship between the width dimension of each light shielding plate 17 of the light shielding plate unit 117 and the width dimension of the side surface of each cell 8 of the series of cells 108 can adopt the relationship described in the first to third embodiments. .

In this way, by integrating the light shielding plate unit 117 and the continuous cell 108, when the continuous cell 108 is removed from the cell disk 9, the light shielding plate unit 117 can also be removed. Maintenance work such as cleaning inside the thermostatic chamber is generally performed by removing the cell 8 from the cell disk 9, and at that time, it is possible to remove the continuous cell 108 and the light shielding plate unit 117 from the cell disk 9 at the same time. becomes. Therefore, the convenience of operating the automatic analyzer 100 can be improved. Furthermore, when replacing a cell 8 that has been used for a long period of time, by removing the light shielding plate unit 117 from the continuous cell 108, only the continuous cell 108 can be replaced, thereby reducing the number of parts that require periodic replacement. It becomes possible.

(6) Summary (i) According to each embodiment, a plurality of light shielding plates 17 having a width wider than the width dimension of the side surface of the cell 8 are arranged between each cell. These plural light shielding plates 17 are configured to prevent the light emitted from the light source 18 from entering the scattered light receiver 21 and to prevent the light emitted from the light source 20 from entering the transmitted light receiver 19. By arranging such a light shielding plate, it becomes possible to prevent stray light from entering each light receiver. Note that, for example, light emitted from the light source 18 passes through the side surface and transparent surface of the cell 8 and enters the adjacent cell 8 or the scattered light receiver 21, or light emitted from the light source 20 passes through the side surface of the cell 8 and enters the scattered light receiver 21. The light that passes through the transparent surface and enters the adjacent cell 8 or transmitted light receiver 19 is defined as stray light. In other words, the plurality of light shielding plates 17 prevent the light emitted from the light source 18 from passing through the side surfaces and transparent surfaces of the cells 8 and entering the adjacent cells 8 and the scattered light receiver 21, and prevent the light emitted from the light source 20 from entering the adjacent cells 8 and the scattered light receiver 21. This prevents light from passing through the side surface and light-transmitting surface of the cell 8 and entering the adjacent cell 8 or the transmitted light receiver 19.

(ii) According to the second embodiment, the plurality of light shielding plates 17 protrude from the ends of the cells 8 toward the light sources 18 and 20. At this time, a notch 41 is provided in the outer periphery (part) of the cell disk 9, and the transmitted light receiver 19 and the scattered light receiver 21 are disposed therein. As a result, the distance from the transmitted light receiver 19 and the scattered light receiver 21 to one end of the cell 8 can be configured to be shorter than the distance from the light sources 18 and 20 to the other end of the cell 8. Therefore, it is possible to reduce the size of the light receiver.

(iii) According to the third embodiment, the plurality of light shielding plates 17 protrude from the end of the cell 8 toward the transmitted light receiver 19 and the scattered light receiver 21 side. At this time, a notch 42 is provided in the inner circumference (part) of the cell disk 9, and the light sources 18 and 20 are arranged here. This allows the distance from the light sources 18 and 20 to one end of the cell 8 to be shorter than the distance from the transmitted light receiver 19 and the scattered light receiver 21 to the other end of the cell 8. Therefore, it is possible to prevent stray light due to reflection from the bottom surface of the cell 8 and the reaction liquid surface 31, and to perform measurement using a smaller amount of reaction liquid.

(iv) According to the fourth embodiment, the plurality of light shielding plates 17 are arranged with an inclination with respect to the rotation direction of the cell disk 9. Thereby, the flow of the constant temperature fluid 15 can be induced between the cells 8 by the rotation of the cell disk 9, and it becomes possible to improve the temperature control performance of the cells 8 and the reaction liquid.

(v) According to the fifth embodiment, the plurality of cells 8 are formed by combining individual cells (continuous cells 108), and the plurality of light shielding plates 17 are formed by combining individual light shielding plates. (continuous light shielding plate 117). Then, by inserting each cell 8 in the continuous cell 108 into the gap between the respective light shielding plates 17 of the continuous light shielding plate 117, the continuous cell 108 and the continuous light shielding plate 117 are configured to be integrated. As a result, only the cell 8 can be replaced, making it possible to reduce the number of parts that require periodic replacement.

1 Sample 2 Sample cup 3 Sample disk 4 Reagent 5 Reagent bottle 6 Reagent disk 7 Reaction liquid 8 Cell 9 Cell disk 10 Sample dispensing mechanism 11 Reagent dispensing mechanism 12 Stirring section 13 Transmitted light measuring section 14 Cleaning section (cleaning mechanism)
15 Constant temperature fluid 16 Scattered light measurement section 17 Light shielding plates 18, 20 Light source 19 Transmitted light receivers 21, 26, 27 Scattered light receiver 22 Irradiated light 23 Transmitted light 24 Forward scattered light 25 Backward scattered light 28 Input slit 29 Light receiving slit 30 Optical axis 31 Reaction liquid surface 32 Flow of constant temperature fluid

Claims (6)

a cell disk in which a plurality of cells for reacting a sample and a reagent are placed in a circular shape;
a first light source and a second light source that irradiate the cell with light;
a first light receiver that detects the light emitted from the first light source;
a second light receiver that detects the light emitted from the second light source;
a plurality of light shielding plates arranged between each of the plurality of cells and having a width wider than a width dimension of a side surface of the cell,
The plurality of light shielding plates are configured to prevent light emitted from the first light source from entering the second light receiver and prevent light emitted from the second light source from entering the first light receiver. , automatic analyzer. In claim 1,
In the automatic analyzer, the plurality of light shielding plates protrude from an end of the cell toward at least one of the first and second light sources or the first and second light receivers. In claim 1,
The plurality of light shielding plates protrude from an end of the cell in a direction toward the first and second light sources,
A notch is provided in a part of the outer periphery of the cell disk,
The first and second light receivers are arranged in the cutout, and the distance from the first and second light receivers to one end of the cell is such that the distance from the first and second light sources to one end of the cell is shorter than the distance to the other end of the automated analyzer. In claim 1,
The plurality of light shielding plates protrude from an end of the cell toward the first and second light receivers,
A notch is provided in a part of the inner periphery of the cell disk,
The first and second light sources are arranged in the notch, and the distance from the first and second light sources to one end of the cell is equal to the distance from the first and second light receivers to the other end of the cell. Automated analyzer, shorter than the distance to one end. In claim 1,
The plurality of light shielding plates are arranged to be inclined with respect to the rotation direction of the cell disk so that the rotation of the cell disk induces a flow of constant temperature fluid contained in the cell disk between the cells. Automatic analyzer. In claim 1,
The plurality of cells are connected cells formed by combining individual cells,
The plurality of light shielding plates are continuous light shielding plates formed by combining individual light shielding plates,
The automatic analyzer is configured such that the continuous cells and the continuous light-shielding plate are integrated by inserting each cell in the continuous cell into a gap between each light-shielding plate of the continuous light-shielding plate.

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