JP7322665B2 - Packaging sheet inspection device - Google Patents

Description

TECHNICAL FIELD The present invention relates to an inspection device for confirming that a solid drug in each packaging bag of a packaging sheet is correct.

In recent years, dispensing pharmacies and the like have come to package drugs for the convenience of patients. That is, in order to take medicines that are taken at the same time or several kinds of medicines at one time, those medicines are collectively enclosed in one package bag. However, the medicine enclosed in the sachet is prepared for each sachet by the pharmacist who has prepared the medicine according to the prescription. Since this work is done by humans, mistakes can occur.

On the other hand, there is a device for confirming that the solid drug is correctly contained in the sachet. As an example of such a device, in order to read the printing or imprint on the surface of the solid drug, there is a device that images a transparent or translucent packaging bag with a camera to determine the printing or imprint (Patent Document 1, Patent document 2). In addition to this, there is a device that reads letters and the like attached to solid medicines by maximizing the contrast between the printed color and the background color, although it does not distinguish the medicines in the sachets (Patent Document 3). ). Furthermore, there is also an apparatus that recognizes the type of drug using a spectrum camera without using an imaging camera (Patent Document 4).

JP 2018-117921 A Japanese Patent No. 6100136 JP 2010-190786 A Japanese Patent No. 5917711

However, while the number and type of drugs in the sachet must be correct, the accuracy of confirmation by each of these devices is not sufficient. Therefore, there is a demand for a device that can accurately confirm the number and types of medicines in a sachet. It is also desirable that the time required for confirmation by the device is short.

The present invention has been made in view of the above circumstances, and an object of the present invention is to enable a sachet containing a plurality of sachets to check the drug in each sachet with high accuracy, and to provide a drug in a short time. It is to provide an inspection device that can be confirmed.

(1) In the present invention, a sheet-shaped sachet having an internal space in which a solid medicine is accommodated, and at least a portion corresponding to the internal space is formed of a translucent film, and is arranged in a row direction. and an inspection device for inspecting packaging sheets arranged in a column direction. This inspection apparatus includes a support section that supports the packaging sheet at a first support position, and a first irradiation section that irradiates visible light from a first direction into the internal space of the packaging bag at the first support position. a second irradiation unit that irradiates the internal space of the sachet at the first support position with visible light from a second direction different from the first direction; and the internal space of the sachet at the first support position. a camera that captures and outputs image data, a first scanning unit that scans the first irradiation unit, the second irradiation unit, and the camera in the row direction and the column direction with respect to the support unit, and a controller , a memory; The controller acquires prescription information and stores it in the memory, and drives the first scanning unit to start from a start position corresponding to a specific sachet and to a different sachet from the specific sachet. moving the first irradiation unit, the second irradiation unit, and the camera in the row direction or the column direction toward each inspection position corresponding to each packaging bag on the packaging sheet toward the end position corresponding to the packaging bag; and driving the first scanning unit to move the first irradiation unit, the second irradiation unit, and the camera from the end position in the row direction or In the second scanning process of sequentially moving to each inspection position adjacent to each other in the column direction, and at each inspection position in the first scanning process, the internal space of the corresponding sachet is irradiated with visible light from the first irradiation unit. Then, at each inspection position in the first imaging process of storing in the memory the first image data obtained by imaging with the camera, and in the first scanning process, the internal space of the corresponding sachet is scanned. A second photographing process of irradiating visible light from a second irradiation unit and storing second image data obtained by photographing with the camera in the memory and each inspection position in the second scanning process, corresponding to each A third photographing process of irradiating the internal space of the sachet with visible light from the first irradiation unit and the second irradiation unit, and storing in the memory third image data obtained by photographing with the camera. and an image of a first solid medicine having a stamp in the first image data corresponding to one sachet stored in the memory, and the first solid medicine in the second image data corresponding to the sachet Synthesizing processing for synthesizing an image of a medicine with an image of the medicine to generate synthetic data; Second judgment processing for judging the printing applied to the medicine, and the type of the solid medicine sealed in each sachet using at least one of the determined imprint of the first solid medicine and the printing of the second solid medicine and a first comparison process of comparing the determination result with the prescription information stored in the memory and outputting the comparison result.

The first irradiation unit, the second irradiation unit, and the camera sequentially move from the start position toward the end position to adjacent inspection positions in the row direction or the column direction, and from the end position, the first irradiation unit and the second irradiation unit Since the unit and the camera sequentially move to adjacent inspection positions in the row or column direction, the first image data and the second image data for determining the stamping of the solid medicine are acquired in the forward pass, and the printing is determined in the return pass. Third image data is obtained for performing. Therefore, the first scanning process and the second scanning process are efficiently performed.

(2) Preferably, the inspection device places the first irradiation section and the second irradiation section at a first irradiation position and relative to the packaging sheet at the first support position relative to the first irradiation position. The controller further includes a moving unit that moves to a second irradiation position which is a closer position, and the controller positions the first irradiation unit at the second irradiation position in the first imaging process, and moves the first irradiation part to the second irradiation position in the second imaging process. The second irradiation section is positioned at the second irradiation position, and the first irradiation section and the second irradiation section are positioned at the first irradiation position in the third imaging process.

By irradiating the visible light with the first irradiation unit or the second irradiation unit positioned at the second irradiation position, the first image data and the second image data are obtained by irradiating the visible light from the first irradiation position. The impression of the stamp of the solid drug in , is darker, and the determination accuracy of the stamp is improved. By irradiating the visible light with the first irradiation unit and the second irradiation unit positioned at the first irradiation position, the impression of the solid drug is obtained in the third image data rather than the irradiation of the visible light from the second irradiation position. is reduced, and the print determination accuracy is improved.

(3) Preferably, the inspection device includes a third irradiation section that irradiates visible light from a third direction different from the first direction and the second direction to the internal space of the sachet at the first support position. and a fourth irradiation unit that irradiates the internal space of the sachet at the first support position with visible light from a fourth direction different from the first direction, the second direction, and the third direction. Further, the first irradiation section, the second irradiation section, the third irradiation section, and the fourth irradiation section are arranged in a ring at mutually different positions in the circumferential direction, and The first scanning unit scans the third irradiation unit and the fourth irradiation unit together with the first irradiation unit and the second irradiation unit in the row direction and the column direction with respect to the support unit. emits visible light from the third irradiation unit to the internal space of the corresponding sachet at each inspection position in the first scanning process, and captures the third image data obtained by the camera. In the fourth photographing process stored in the memory and at each inspection position in the first scanning process, the internal space of the corresponding sachet is irradiated with visible light from the fourth irradiation unit and photographed by the camera. and a fifth photographing process of storing in the memory the fourth image data obtained by the above process, and in the combining process, the image of the first solid medicine in the first image data and the image of the first solid drug in the sachet The image of the first solid drug in the corresponding second image data, the image of the first solid drug in the third image data corresponding to the sachet, and the fourth image corresponding to the sachet. and the image of the first solid drug in the data are combined to generate the combined data.

According to the above configuration, the accuracy of marking determination is further improved.

(4) Preferably, the support section supports the packaging sheet at a second support position different from the first support position, and the memory stores frequency characteristics including spectrum data of a plurality of types of solid drugs. A database is stored, and the inspection device includes a near-infrared light irradiation unit that irradiates near-infrared light to the inner space of the sachet at the second support position, and the sachet at the second support position. A spectrum camera that receives near-infrared light reflected from the inner space of the bag and outputs spectrum data, and the near-infrared light irradiation unit and the spectrum camera are scanned in the row direction and the column direction with respect to the support part. The controller drives the second scanning unit to move the packaging sheet to each inspection position corresponding to each packaging bag of the packaging sheet at the second support position. , a third scanning process in which the near-infrared light irradiation unit and the spectral camera are sequentially moved to adjacent inspection positions in the row direction or the column direction; A sixth photographing process of irradiating near-infrared light from the near-infrared light irradiation unit into the inner space of the bag and storing the spectrum data output from the spectrum camera in the memory, and a specific solid medicine in the spectrum data. and the spectrum data of the solid drug in the frequency characteristic database to determine the type of the specific solid drug, and compare the determination result with the prescription information stored in the memory. and a second comparison process for outputting a result.

According to the inspection apparatus of the present invention, it is possible to check the medicine in each of the packaging sheets made up of a plurality of packaging bags with high accuracy and in a short period of time.

FIG. 1 is a side view of the inspection device 10. FIG. FIG. 2 is a top view of the inspection device 10. FIG. FIG. 3 is a top view of the packaging sheet 20 to be inspected by the inspection device 10. FIG. FIG. 4 is a bottom view of the illumination device 42, and (A) to (D) are diagrams respectively showing the operation of the illumination bodies 14-1 to 14-4 in the first scanning process. FIG. 5 is a bottom view of the illumination device 42, showing the operation of the illumination bodies 14-1 to 14-4 in the second scanning process. FIG. 6 is a schematic side view showing the position of the illumination device 42 with respect to the packaging sheet 20. As shown in FIG. FIG. 7 is a block diagram of the inspection device 10. As shown in FIG.

Hereinafter, embodiments of the present invention will be described with reference to the drawings as appropriate. It should be noted that the embodiment described below is merely an example of the present invention, and it goes without saying that the embodiment of the present invention can be modified as appropriate without changing the gist of the present invention.

[Inspection device 10]
As shown in FIGS. 1 and 2, the inspection apparatus 10 has a conveying device 30, an image inspection section 40, a component inspection section 50 and a control device 60. FIG. The inspection device 10 inspects the packaging sheets 20 conveyed by the conveying device 30 .

[Package sheet 20]
As shown in FIG. 3, the packaging sheet 20 has a plurality of packaging bags 21 arranged in the row direction X1 and the column direction Y1. In the packaging sheet 20, the packaging bags 21 that are adjacent in the row direction X1 and the column direction Y1 are in contact at boundaries 22 of perforations. The packaging sheet 20 corresponds to packaging of medicines in one package. Therefore, in the illustrated example, four sachets 21 are lined up in the row direction X1, and one or more solid medicines are individually packaged in each of these for morning, noon, evening and before bedtime. . In the illustrated example, seven sachets 21 are lined up in the column direction Y1, and these are for taking medication on each day of the week.

The sachets 21 are rectangular in plan view, and each has an internal space 21a. The sachet 21 is made of a translucent film at least at a portion corresponding to the internal space 21a. Such a film is, for example, a synthetic resin film. One or more solid medicines 3 are accommodated in the internal space 21a of the sachet 21 . The solid drug 3 includes not only tablets but also capsules. Alternatively, the tablet may be a half tablet divided by a score line. The surface of the solid medicine 3 is usually printed or stamped with the product name and identification code of the medicine. As will be described in detail below, the inspection apparatus 10 according to the present embodiment determines the product name and identification code printed or stamped on the solid medicine 3 from the image, determines the components of the solid medicine 3, It is inspected whether the medicine is properly packaged in each of the packaging bags 21 of the packaging sheet 20.例文帳に追加

[Conveyor 30]
As shown in FIGS. 1 and 2, the conveying device 30 is arranged below the image inspection section 40 and the component inspection section 50 . The conveying device 30 has a conveying belt 32 (an example of a support section), a driving pulley 34 and a driven pulley 36 . The drive pulley 34 is connected to a motor (not shown), and is rotated by the drive of the motor. This motor (not shown) is connected to the control device 60 of the inspection device 10 and controlled by the control device 60 . The driven pulley 36 rotates following the rotation of the drive pulley 34 . The rotation of these pulleys 34 and 36 drives the conveyor belt 32 in the row direction X2 opposite to the row direction X1 (see FIG. 3) of the packaging sheets 20 . In this way, the packaging sheet 20 placed on the conveyor belt 32 is conveyed directly below the image inspection section 40 or the component inspection section 50 . Here, as the position of the packaging sheet 20, the position directly below the image inspection unit 40 is the image inspection position (first support position) P1, and the position directly below the component inspection unit 50 is the component inspection position (second support position) P2. That is, the conveyor belt 32 supports the packaging sheet 20 at the image inspection position P1 and the component inspection position P2.

[Image inspection unit 40]
The image inspection section 40 includes a visible light illumination device 42 , a digital color camera 44 , and an image inspection scanning device 46 . The visible light illumination device 42 has an annular shape and consists of a support portion 12 positioned above and an illuminator group 13 positioned below. The visible light illumination device 42 is composed of eight illuminators 13a as shown in FIGS. 4A and 4B when the illuminator group 13 is viewed from below. The illuminator group 13 is annular, and the illuminator 13a is obtained by dividing the annular illumination portion 13 into eight equal parts along the circumferential direction. In this embodiment, these eight illuminators 13a constitute the illumination body 14 with a pair of illuminators 13a adjacent to each other. Therefore, in the illustrated example, the illuminator group 13 includes first to fourth illuminators (irradiating units) 14-1 to 14-4.

The illuminators 13a are, for example, LED (light emitting diode) illuminators in the visible wavelength range. However, the illuminator 13a may be any illuminator as long as it emits visible light and is useful for photographing by the digital color camera 44. FIG. These illuminators 13a can be individually controlled, but in this embodiment, each illuminator 14 is activated and deactivated. Although not shown, the visible light illumination device 42 is movably supported together with the digital color camera 44 .

The digital color camera 44 is, for example, a CCD digital color camera. The digital color camera 44 is arranged so that the lens faces straight down. In other words, the digital color camera 44 can take an image of an object positioned directly below. Therefore, the digital color camera 44 can photograph one or more packaging bags 21 of the packaging sheet 20 when the packaging sheet 20 is positioned at the image inspection position P1.

The image inspection scanning device 46 includes a first arm 46a extending in the left-right direction X and connected to the digital color camera 44, and a second image scanning arm 46b extending in the front-back direction Y connected to the first image scanning arm 46a. and For example, driving of a motor (not shown) is transmitted to move the digital color camera 44 in the horizontal direction X along the first arm 46a for image scanning. Similarly, for example, the first image scanning arm 46a moves in the front-rear direction Y along the second image scanning arm 46b by transmitting the drive of a motor (not shown). The front-rear direction Y is both the row direction X1 of the packaging sheets 20 placed on the conveyor belt 32 and the row direction X2 of the conveyor belt 32 . Similarly, the horizontal direction X is both the row direction Y1 of the packaging sheets 20 placed on the conveyor belt 32 and the opposite direction Y2.

With the above configuration, the digital color camera 44 can move in the front-rear direction Y and in the left-right direction X. As shown in FIG. As a result, the photographing location of the digital color camera 44 is changed. Further, since the visible light illumination device 42 is supported by the digital color camera 44 as described above, the visible light illumination device 42 is also moved in the front-rear direction Y and the left-right direction X in conjunction with the digital color camera 44 .

The image inspection scanning device 46 also includes a moving mechanism (not shown) for moving the visible light illumination device 42 in the vertical direction Z. As shown in FIG. Thereby, as shown in FIG. 6, the visible light illumination device 42 can move between an upper position P11 indicated by a solid line and a lower position P12 indicated by a two-dot chain line. A case where the visible light illumination device 42 is arranged at the upper position P11 and a case where it is arranged at the lower position P12 will be described in detail later.

[Component inspection unit 50]
The component inspection unit 50 includes a near-infrared illumination device 52 , a near-infrared spectrum camera 54 , and a scanning device 56 for component inspection. The near-infrared illuminator 52 is two LED illuminators 52a along the front-rear direction Y, and consists of the LED illuminators 52a in the near-infrared wavelength region. In this embodiment, these LED illuminators 52a are activated and deactivated at the same time. The near-infrared illuminator 52 is supported by a near-infrared spectrum camera 54 above via a plurality of links (not shown).

The near-infrared spectrum camera 54 is a line scanning hyperspectral camera. Therefore, the near-infrared spectrum camera 54 acquires a line-shaped hyperspectral image and scans the line. In this way, the near-infrared spectrum camera 54 acquires the wavelength distribution in the lower horizontal plane.

The component inspection scanning device 56 includes a component inspection first arm 56a that is connected to the near-infrared spectrum camera 54 and extends in the left-right direction X, and a component inspection first arm 56a that is connected to the component inspection first arm 56a and extends in the front-rear direction Y. and a second arm 56b for use. For example, the near-infrared spectrum camera 54 moves in the front-rear direction Y along the component inspection first arm 56a by transmitting the drive of a motor (not shown). Similarly, for example, the second component inspection arm 56a moves in the front-rear direction Y along the second component inspection arm 56b by transmitting the drive of a motor (not shown). Since the near-infrared illuminating device 52 is supported by the near-infrared spectrum camera 54 as described above, both the near-infrared illuminating device 52 and the near-infrared spectrum camera 54 move forward and backward in conjunction with the near-infrared spectrum camera 54 . It is moved in the Y direction and the X left and right direction.

[Control device 60]
The control device 60 is a device that is connected to the image inspection section 40 and the component inspection section 50 and controls these inspection sections 40 and 50 . The controller 60 has a controller 62 and a memory 64, as shown in FIG. The controller 60 has a user interface 63, either internally or externally as shown, for entering prescription information. The user interface 63 is, for example, a screen and an input device (keyboard or mouse) for manual input by a pharmacist or the like. When the prescription information is electronic data, the user interface 63 may be a communication unit (not shown) or a terminal (not shown) for a USB (Universal Serial Bus) memory or the like.

Controller 62 includes an integrated control module 66 and acquisition module 68 for the entire examination. For image inspection, the controller 62 includes an outward scanning module 71, a first outward imaging module 72, a second outward imaging module 73, a synthesizing module 74, a marking determination module 75, a backward scanning module 76, a backward imaging module 77, and a print determination module. module 78 , and imaging contrast module 79 . The controller 62 further comprises a line scan module 81, a spectral imaging module 82, and a component inspection contrast module 83 for component inspection.

The memory 64 includes a prescription data storage unit 90, a frequency characteristic database 91, a first intermediate image data storage unit 92, a second intermediate image data storage unit 93, an engraving image data storage unit 94, a printing image data storage unit 95, and A spectrum data storage unit 96 is provided. The processing by each of the above modules and the writing and reading of the above data by these modules will be described later in connection with the description of the method of operation of inspection apparatus 10. FIG.

1 and 2, the control device 60 is provided on the side of the conveying device 30, but the control device 60 may be provided at any location. For example, controller 60 may be implemented in a personal computer. In that case, the control device 60 may be connected to the conveying device 30, the image inspection section 40, and the component inspection section 50 by wire or wirelessly. Also, the control device 60 may be implemented by being distributed to a plurality of devices or computers.

[Method of Operation of Inspection Apparatus 10]
The method of operation of the inspection apparatus 10 will now be described with reference to FIGS. 1 to 7. FIG. First, it is assumed that one or more packaging sheets 20 prepared by a pharmacist dispensing medicines according to a prescription and packing them into one package are prepared. Prescription information is entered into controller 60 via user interface 63 before or after pharmacist dispensing. The acquisition module 68 acquires this prescription information and stores it in the prescription data storage unit 90 as prescription data (an example of acquisition processing). The frequency characteristic database 91 includes spectral data of multiple types of solid medicines 3 .

The prepared packaging sheet 20 is placed, for example, on the conveyor belt 32 or a mounting section connected to the conveyor belt 32 . 1 and 2 show a state in which two packaging sheets 20 are placed on the conveyor belt 32, however, any number of packaging sheets 20 may be placed.

[Image inspection]
When one packaging sheet 20 to be inspected reaches the image inspection position P1, the integrated control module 66 sends a command to the outward scanning module (module for executing the first scanning process) 71 . This command initiates the image inspection. In this embodiment, the visible light illumination device 42 is positioned at the lower position P12 shown in FIG. 6 at the start of the image inspection. It is also assumed that the digital color camera 44 and the visible light illumination device 42 are at their starting positions at the start of the image inspection. These starting positions are the digital color camera 44 and the visible light illumination device for photographing a specific packaging bag 21 (in the illustrated example, the packaging bag 21-S on the upper right of the page) of the packaging sheet 20 in FIG. 42 is the suitable horizontal position. At this starting position, only the internal space 21a of the sachet 21-S needs to be photographed, and the internal spaces 21a of the other sachets 21 are not photographed.

In this state, the first forward imaging module (module for executing the first imaging process) 72 operates the illumination body 14-1 (FIG. 4(A)) to (Fig. 4(A)) remains stopped. In FIG. 4, the illuminators 13a that are turned on by operation are hatched, and the illuminators 13a that are turned off by stopping are not hatched. The first forward trip photographing module 72 then photographs the internal space 21 a of the sachet 21 -S with the digital color camera 44 and stores the photographed image in the first intermediate image data storage section 92 . After that, the second forward photographing module (module for executing the second photographing process) 73 stops the illumination body 14-2 (FIG. 4A) and restarts the illumination body 14-2 (FIG. 4A). Operate. The second forward trip photographing module 73 then photographs the internal space 21a of the sachet 21-S with the digital color camera 44 and stores the photographed image in the second intermediate image data storage unit 93. FIG. Although not shown in FIG. 7, the controller 62 further includes third and fourth forward imaging modules, and the memory 64 includes third and fourth intermediate image data storage units. The third and fourth forward photographing modules (the module for executing the fourth photographing process and the module for executing the fifth photographing process) follow the first and second outward photographing modules, respectively. 4(C)) or 14-4 (FIG. 4(D)) is operated, the internal space 21a of the sachet 21-S is photographed by the digital color camera 44, and these images are obtained as third and third images, respectively. 4 Store in the intermediate image data storage unit.

In this way, with the visible light illumination device 42 positioned at the lower position P12, the illumination bodies 14-1 to 14-4 irradiate the internal space 21a of the sachet 21-S with visible light from one obliquely upper direction. Therefore, if the solid medicine 3 in the internal space 21a is stamped, a shadow along the edge of the stamp appears in each image data. Since the shadow along the edge of the stamp differs depending on the irradiation direction of the visible light, when the image data written in the first to fourth intermediate image data storage units are synthesized by the synthesizing module (module for performing synthesizing processing) 74, Shadows along all the edges of the engraving applied to the solid medicine 3 clearly appear in the synthesized image. It should be noted that a known technique is employed for the process of synthesizing the images. The synthesizing module 74 stores data of the synthesized image in the stamp image data storage unit 94 . Note that the imprint of the solid medicine 3 clearly appears in the synthesized image. It is also possible to recognize the shape of each solid drug 3 from the synthesized image. Therefore, the number of solid medicines 3 in each sachet 21 is determined.

The engraving determination module (module that executes the first determination process) 75 determines engraving of the engraved solid medicine 3 from the combined data stored in the engraving image data storage unit 94 . A well-known technique is adopted for image processing for judging the engraving.

After that, the outward scanning module 71 drives the image inspection scanning device 46 to detect the digital color camera 44 and the visible light illumination device 42 in a packaging bag (illustrated) different from the packaging bag 21-S positioned at the starting position. In this example, the package bag 21-E) at the bottom left of the page is moved to a position suitable for photographing in the following procedure. Specifically, the forward scanning module 71 moves the digital color camera 44 and the visible light illumination device 42 to the sachets adjacent to the sachets 21-S (in the illustrated example, below the surface of the sachets 21-S). (21-12) is moved to a position suitable for photographing. In this state, the first to fourth forward imaging modules perform the same processing as in the case of the sachet 21-S, and the stamp determination module 75 determines the stamp of the solid medicine 3 that has been stamped.

The outward scanning module 71 similarly scans the digital color camera 44 and the visible light illumination device 42 to the packaging bag adjacent to the packaging bag 21-12 (in the illustrated example, the part below the paper surface of the packaging bag 21-12). The package 21-13) is moved to a position suitable for photographing, and similar processing is performed. (in the illustrated example, the packaging bag 21-14 below the paper surface of the packaging bag 21-13) is moved to a position suitable for photographing, and similar processing is performed. This process is repeated for each sachet 21 along the route indicated by the two-dot chain line in FIG. That is, when it moves sequentially to the packaging bag 21 on the lower side of the page and reaches the lowermost packaging bag 21 on the page, it moves to the packaging bag 21 on the left side of the page and then sequentially moves to the packaging bag 21 on the upper side of the page. When it reaches the uppermost packaging bag 21 on the page, it moves to the packaging bag 21 on the left side of the page. In this way, similar processing is performed up to the sachet 21-E corresponding to the end position.

As described above, it is possible to determine the marking of the solid medicine 3 on which all the packaging bags 21 have been marked. Note that the determination processing by the stamp determination module 75 may be performed collectively after the combined data for all the packaging bags 21 is stored in the stamp image data storage unit 94 .

A moving mechanism (not shown) moves the visible light illumination device 42 from the lower position P12 to the upper position P11. Then, the return photographing module (module for executing the third photographing process) 77 operates all the illumination bodies 14-1 to 14-4, as shown in FIG. Next, the return trip photographing module 77 photographs the internal space 21a of the sachet 21-E with the digital color camera 44, and stores the image in the image data storage unit 95 for printing.

In this way, with the visible light illumination device 42 positioned at the upper position P11, the illumination bodies 14-1 to 14-4 irradiate the internal space 21a of the sachet 21-S with visible light from all obliquely upward directions. Therefore, if printing is applied to the solid medicine 3 in the internal space 21a, it is difficult for a stamp impression to appear in the photographed image, and the printing appears clearly. The return photographing module 77 stores data of the photographed image in the print image data storage unit 95 . A print determination module (a module that executes a second determination process) 78 determines printing of the printed solid medicine 3 from the image data stored in the print image data storage unit 95 . Note that a known technique is employed for image processing for determining printing. The image data also allows recognition of the shape of each solid medicine 3 . As described above, the number of solid medicines 3 in each sachet 21 is determined from the image data in the image data storage unit 94 for stamping. The number of solid medicines 3 in each sachet 21 may be determined from the image data. Using the image data in both storage units 94 and 95 improves the accuracy of inspection.

After that, the inward scanning module 76 drives the image inspection scanning device 46 to move the digital color camera 44 and the visible light illumination device 42 from the end position to the sachet adjacent to the sachet 21-E (shown in the figure). In the example, the sachet 21-73) on the paper surface of the sachet 21-E is moved to a position suitable for photographing. In this state, the return trip photographing module 77 performs the same processing as in the case of the sachet 21-E, and stores the data of the photographed image in the image data storage unit 94 for engraving.

The return scanning module 76 similarly scans the digital color camera 44 and the visible light illumination device 42 to the sachets adjacent to the sachets 21-73 (in the illustrated example, the division of the sachets 21-73 on the paper surface). The package 21-72) is moved to a position suitable for photographing, and similar processing is performed. (in the illustrated example, the packaging bag 21-71 on the paper surface of the packaging bag 21-72) is moved to a position suitable for photographing, and similar processing is performed. This process is repeated for each sachet 21 along the route indicated by the two-dot chain line in FIG. That is, the scanning path of the forward scanning module 71 is reversed to sequentially move to the packaging bag 21, and the same processing is performed until reaching the packaging bag 21-S corresponding to the start position.

As described above, it is possible to determine whether the printed solid medicine 3 is printed on all the sachets 21 . Note that the determination processing by the print determination module 78 may be performed collectively after the image data for all the packaging bags 21 is stored in the print image data storage unit 95 .

The image inspection comparison module (module that executes the first comparison processing) 79 is the stamp of the stamped solid medicine 3, and the stamp determined by the stamp determination module 75 and the printed solid medicine 3 using at least one of the markings determined by the print determination module 78 to determine the type (product name or identification number) of the solid medicine 3 enclosed in each sachet 21, and the determination result and the prescription information stored in the prescription data storage unit 90, and the result of the comparison is output to a screen inside or outside the control device 60. FIG. This screen may be a user interface 63 into which prescription information is entered. Note that the output of the comparison result may be output only when the determination result and the prescription information do not match. It is preferable that the sachets 21 in which the determination result and the prescription information do not match are specified in the output comparison result.

[Component inspection]
After the image inspection, the packaging sheet 20 is transported from the image inspection position P1 to the component inspection position P2 by the transport device 30 . However, in the comparison result, if the determination result and the prescription information do not match, the packaging sheet 20 may be conveyed beyond the component inspection position P2 to the take-out position (not shown). In other words, since there is a possibility that the drug is not properly packaged in at least one sachet 21, even if the image inspection comparison module 79 outputs so as to prompt the pharmacist's visual confirmation without performing the ingredient inspection, good.

When the packaging sheet 20 that has passed the image inspection reaches the component inspection position P2 from the image inspection position P1, the integrated control module 66 sends a command to the line scanning module (module for executing the third scanning process) 81. This command initiates component inspection. In this embodiment, it is assumed that the near-infrared spectrum camera 54 and the near-infrared illumination device 52 are at their starting positions at the start of the component inspection. These start positions are the near-infrared spectrum camera for line scanning from the left end of the paper surface of the specific packaging bag 21 (in the illustrated example, the packaging bag 21-E at the bottom left of the paper surface) of the packaging sheet 20 in FIG. 54 and the near-infrared illuminator 52 are suitable horizontal positions. At this position, the near-infrared illumination device 52 can irradiate the near-infrared rays to the left end portion of the paper surface of the sachet 21-E, and the near-infrared spectrum camera 54 can detect the sachet 21-E and its interior at line 5 in the figure. Acquire spectral data from an object.

When the component inspection starts, the line scanning module 81 drives the component inspection scanning device 56 to perform line scanning of the near-infrared spectrum camera 54 and the near-infrared illumination device 52 along the row direction X1. During line scanning, the spectral imaging module (module that executes the sixth imaging process) 82 irradiates the line 5 with near-infrared light from the near-infrared illumination device 52, and the near-infrared spectral camera 54 detects that line. Acquire the spectroscopic spectrum from 5. Therefore, if the line 5 is scanned in the row direction X2, a rectangular space extending over the sachets 21-E, 21-64, 21-54, 21-44, 21-34, 21-24, and 21-14 in plan view is obtained, and the spectral imaging module 82 stores the spectral data in the spectral data storage unit 96 .

The conveying device 30 or the component inspection scanning device 56 is provided with an encoder (not shown). Encoders detect the displacement positions of the near-infrared spectrum camera 54 and the near-infrared illumination device 52 . From this displacement position, the relationship between the sachets 21-E, 21-64, . Further, it is determined from the displacement position that the near-infrared spectrum camera 54 and the near-infrared illumination device 52 have reached the right end of the packaging bag 21-14 on the lower right of the page, and the component inspection scanning device 56 is stopped. be done.

Next, the line scanning module 81 drives the component inspection scanning device 56 so that the line 5 is positioned at the right end of the paper surface of the packaging bag 21-14 on the lower right side of the paper surface and the packaging bag 21-13 on the upper side of the paper surface. , moves the near-infrared spectrum camera 54 and the near-infrared illuminator 52 . Thereafter, the line scanning module 81 drives the component inspection scanning device 56 to perform line scanning of the near-infrared spectrum camera 54 and the near-infrared illumination device 52 in the row direction X2. During line scanning, the spectral imaging module 82 irradiates the line 5 with near-infrared light from the near-infrared illumination device 52 , and the near-infrared spectrum camera 54 acquires the spectrum from the line 5 . Therefore, by scanning the line 5 in the row direction X2, spectrum data in a rectangular space in plan view over the sachets 21-13, 21-23, . 82 stores the spectral data in the spectral data storage unit 96 .

Similarly, the line 5 is scanned in the row direction X1 from the sachets 21-72 on the upper side of the sachets 21-73, and the sachets 21-72, 21-62, . Spectral data in a rectangular space covering 12 in plan view is acquired, and the spectral imaging module 82 stores the spectral data in the spectral data storage unit 96 . Furthermore, in the same manner, the line 5 is scanned in the row direction X2 from the sachet 21-S on the upper side of the sachet 21-12, and the sachets 21-S, 21-21, . Spectral data in a rectangular space extending from −71 in plan view is obtained, and the spectral imaging module 82 stores the spectral data in the spectral data storage unit 96 .

The component inspection comparison module (module for executing the second comparison process) 83 compares the spectrum information of the specific solid drug 3 in the spectrum data storage unit 96 with each spectrum data stored in the frequency characteristic database 91, The type of solid drug 3 is determined. The component test comparison module 83 compares this determination result with the prescription information stored in the prescription data storage unit 90 and outputs the comparison result to a screen inside or outside the control device 60 . This screen may be a user interface 63 into which prescription information is entered. Note that the output of the comparison result may be output only when the determination result and the prescription information do not match. It is preferable that the sachets 21 in which the determination result and the prescription information do not match are specified in the output comparison result.

[Action and effect of the embodiment]
According to the above-described embodiment, the first irradiation unit 14-1 and the second irradiation unit 14- 2, and a first scanning process in which the camera 44 is sequentially moved to adjacent inspection positions in the row direction or the column direction, and the first and second forward scanning modules 71 perform the first irradiation from the end position to the start position. Since the backward scanning module 76 executes the second scanning process in which the unit 14-1, the second irradiation unit 14-2, and the camera 44 are sequentially moved to adjacent inspection positions in the row direction or the column direction, the solid medicine 3 1st intermediate image data and second intermediate image data for judging engraving are acquired, and printing image data for judging printing in the return pass are acquired. Therefore, the first scanning process and the second scanning process can be efficiently performed.

Further, the first irradiation unit 14-1 is positioned at the second irradiation position P12 in the first imaging process by the first outward imaging module 72, and the second irradiation unit 14-2 is positioned in the second imaging process by the second outward imaging module 73. is positioned at the second irradiation position P12, the first and second irradiation units 14-1 and 14-2 are positioned at the first irradiation position P11 in the third photographing process by the backward photographing module 77, and from the first irradiation position P11 Also, since the second irradiation position P12 is close to the packaging sheet 20, by irradiating visible light from the first irradiation unit 14-1 and the second irradiation unit 14-2 positioned at the second irradiation position P12, solid medicine The irradiation angle for the Therefore, the shadow of the stamp given to the solid medicine 3 becomes clear. Further, by irradiating visible light from the first irradiation unit 14-1 and the second irradiation unit 14-2 positioned at the first irradiation position P11, the entire internal space 21a of the sachet 21 can be uniformly illuminated. can be done. Furthermore, in each of the first scanning process and the second scanning process, the positions of the first irradiation section 14-1 and the second irradiation section 14-2 are moved between the first irradiation position P11 and the first irradiation position P12. Since there is no need, the first scanning process and the second scanning process are performed efficiently.

In addition, the first irradiation section 14-1, the second irradiation section 14-2, the third irradiation section 14-3, and the fourth irradiation section 14-4 are annularly arranged at mutually different positions in the circumferential direction. At each inspection position in one scanning process, the internal space 21a of the corresponding sachet 21 is irradiated with light from the first to fourth irradiation units 14-1 to 14-4, and photographed by the camera 44. 3 is irradiated with visible light from four directions. Therefore, the shadow of the entire imprint of the solid medicine 3 becomes clear.

Further, since the spectral data is acquired at the second supporting position P2 different from the first supporting position P1, in addition to the determination of the type based on the engraving or printing applied to the solid medicine 3, the spectral information of the solid medicine 3 can also be used. A determination of type is made. Therefore, the accuracy of determining the type of solid medicine 3 is improved.

[Modification]
Although the embodiments of the present invention have been described in detail above, the above description is merely illustrative of the present invention in every respect. It goes without saying that various modifications and variations can be made without departing from the scope of the invention. Regarding each component of the inspection apparatus 10 according to the above embodiment, the component may be omitted, replaced, or added as appropriate according to the embodiment.

For example, the scanning path of the packaging sheet 20 indicated by the chain double-dashed line in FIG. , can be any path. Also, different scanning paths may be taken in the first scanning process by the forward scanning module 71 and the second scanning process by the backward scanning module 76 .

In the above embodiment, the digital color camera 44 and the visible light illumination device 42 are moved horizontally by the scanning device 46 for image inspection. It may be horizontally moved on a horizontally movable support (not shown). That is, as long as the digital color camera 44 and the visible light illumination device 42 and the packaging sheet 20 can move relative to each other, any element may move.

In the above-described embodiment, the second imaging process for determining the printing applied to the solid medicine 3 is executed after the first imaging process for determining the stamp applied to the solid medicine 3. , the order of these processes may be reversed. Also, the order of image inspection and component inspection may be reversed.

Further, in the above-described embodiment, the first imaging process and the second imaging process are executed while scanning all the packaging bags 21 of the packaging sheet 20. The first photographing process and the second photographing process may be performed only for the bag 21, and another photographing process other than the first photographing process and the second photographing process may be performed in scanning the other sachets 21. For example, when scanning four sachets 21 arranged in the row direction X1 in the morning, afternoon, evening, and before bedtime, the first imaging process and the second photographic process are executed, and the other 24 sachets are scanned. In the scanning of 21, an imaging process capable of counting the number of solid medicines 3 contained in each sachet 21 may be executed. To count the number of solid medicines 3, for example, edge detection processing is performed on the image of the sachet 21 captured by the image inspection unit 40, and the number of shapes surrounded by edges is counted. treatment can be used. In the scanning of the four sachets 21 arranged in at least one row direction X1, the first imaging process and the second imaging process are executed, so that the solid medicines 3 in the sachets 21 can be confirmed with high accuracy. For the other sachets 21, the positions in the same row direction X1, that is, the dosing timings in the morning, noon, evening, and before bedtime are the same, and the first imaging process and the second imaging process are performed. Since the same number of solid medicines 3 as the number of solid medicines 3 in each sachet 21 that has been executed is enclosed, the solid medicines 3 can be easily confirmed. As a result, the confirmation time of the solid medicine 3 for one packaging sheet 20 can be further shortened.

Moreover, the packaging sheet 20 to be inspected by the inspection device 10 is not necessarily limited to a plurality of packaging bags 21 arranged in the row direction X1 and the column direction Y1. A plurality of sachets 21 may be arranged side by side. That is, the first imaging process and the second imaging process may be performed when scanning is performed only in the row direction X1 or only in the column direction Y1.

3 Solid drug 10 Inspection device 14-1 First irradiation unit 14-2 Second irradiation unit 14-3 Third irradiation unit 14-4 Fourth Irradiation unit 20 Package sheet 21 Package bag 21a Internal space 32 Support unit 44 Camera 46 First operation unit 62 Controller 64 Memory P1... First support position P11... First irradiation position P12... Second irradiation position

Claims (4)

Sheet-shaped sachets having an internal space containing a solid drug, and at least a portion corresponding to the internal space being made of a translucent film are arranged in rows and columns. An inspection device for inspecting a package sheet,
a support portion that supports the packaging sheet at the first support position;
a first irradiation unit that irradiates visible light from a first direction into the internal space of the sachet at the first support position;
a second irradiation unit that irradiates visible light from a second direction different from the first direction to the internal space of the sachet at the first support position;
a camera that captures an image of the internal space of the sachet at the first support position and outputs image data;
a first scanning unit that scans the first irradiation unit, the second irradiation unit, and the camera in the row direction and the column direction with respect to the support unit;
a controller;
with a memory and
The above controller is
an acquisition process of acquiring prescription information and storing it in the memory;
By driving the first scanning unit, each sachet of the sachet is scanned from the start position corresponding to the specific sachet to the end position corresponding to the sachet different from the specific sachet. a first scanning process in which the first irradiation unit, the second irradiation unit, and the camera are sequentially moved to inspection positions adjacent to each other in the row direction or the column direction to each inspection position corresponding to the bag;
driving the first scanning unit to sequentially move the first irradiation unit, the second irradiation unit, and the camera from the end position to each inspection position adjacent in the row direction or the column direction; a scanning process;
At each inspection position in the first scanning process, the first image data obtained by irradiating the internal space of the corresponding sachet with visible light from the first irradiation unit and photographing with the camera is stored in the memory. a first photographing process to be stored in
At each inspection position in the first scanning process, the internal space of the corresponding sachet is irradiated with visible light from the second irradiation unit, and the second image data obtained by photographing with the camera is stored in the memory. a second photographing process to be stored in
At each inspection position in the second scanning process, the internal space of the corresponding sachet is irradiated with visible light from the first irradiation unit and the second irradiation unit and photographed by the camera. a third imaging process of storing three image data in the memory;
An image of a first solid drug having a stamp in the first image data corresponding to one sachet stored in the memory, and an image of the first solid drug having a stamp in the second image data corresponding to the sachet a synthesis process for synthesizing an image and generating synthesized data;
a first determination process for determining the stamp given to the first solid medicine from the combined data;
a second determination process for determining printing applied to the second solid medicine in the third image data;
The type of the solid drug enclosed in each sachet is determined using at least one of the determined stamping of the first solid drug and printing of the second solid drug, and the determination result and the above stored in the memory are determined. and a first comparison process for comparing the prescription information with the prescription information and outputting a comparison result. Move the first irradiation section and the second irradiation section to a first irradiation position and a second irradiation position which is closer than the first irradiation position to the packaging sheet at the first support position. It is further equipped with a moving part,
The above controller is
positioning the first irradiation unit at the second irradiation position in the first imaging process;
positioning the second irradiation unit at the second irradiation position in the second imaging process;
The inspection apparatus according to claim 1, wherein the first irradiation section and the second irradiation section are positioned at the first irradiation position in the third imaging process. a third irradiation unit that irradiates visible light from a third direction different from the first direction and the second direction to the internal space of the sachet at the first support position;
a fourth irradiation unit that irradiates the internal space of the sachet at the first support position with visible light from a fourth direction different from the first direction, the second direction, and the third direction; and
The first irradiation section, the second irradiation section, the third irradiation section, and the fourth irradiation section are annularly arranged at different positions in the circumferential direction,
The first scanning unit scans the third irradiation unit and the fourth irradiation unit together with the first irradiation unit and the second irradiation unit in the row direction and the column direction with respect to the support unit,
The above controller is
At each inspection position in the first scanning process, the internal space of the corresponding sachet is irradiated with visible light from the third irradiation unit, and the third image data obtained by photographing with the camera is stored in the memory. a fourth photographing process to be stored in
At each inspection position in the first scanning process, the fourth image data obtained by irradiating the internal space of the corresponding sachet with visible light from the fourth irradiation unit and photographing with the camera is stored in the memory. further executing a fifth photographing process to be stored in
In the synthesizing process, the image of the first solid medicine in the first image data, the image of the first solid medicine in the second image data corresponding to the sachet, and the image of the first solid medicine corresponding to the sachet 2. The combined data is generated by synthesizing the image of the first solid drug in the third image data and the image of the first solid drug in the fourth image data corresponding to the sachet. Or the inspection device according to 2. The support portion supports the packaging sheet at a second support position different from the first support position,
The memory stores a frequency characteristic database containing spectral data of a plurality of types of solid drugs,
a near-infrared light irradiation unit that irradiates near-infrared light to the inner space of the sachet at the second support position;
a spectral camera that receives near-infrared light reflected from the inner space of the sachet at the second support position and outputs spectral data;
a second scanning unit that scans the near-infrared light irradiation unit and the spectrum camera in the row direction and the column direction with respect to the support unit,
The above controller is
By driving the second scanning unit, the near-infrared light irradiation unit and the spectral camera are moved in a row direction or a column direction to each inspection position corresponding to each packaging bag of the packaging sheet at the second support position. a third scanning process of sequentially moving to adjacent inspection positions in the direction;
At each inspection position in the third scanning process, the near-infrared light is irradiated from the near-infrared light irradiation unit to the inner space of the corresponding sachet, and the spectrum data output by the spectrum camera is stored in the memory. a sixth photographing process to be stored;
The type of the specific solid drug is determined by comparing the spectral information of the specific solid drug in the spectral data with the spectral data of the solid drug in the frequency characteristic database, and the determination result and the above stored in the memory. 4. The inspection apparatus according to any one of claims 1 to 3, which performs a second comparison process of comparing the prescription information and outputting a comparison result.

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