JP7293217B2 - 分析物データの無線通信のための糖尿病管理パートナインターフェース - Google Patents
分析物データの無線通信のための糖尿病管理パートナインターフェース Download PDFInfo
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Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7959598B2 (en) | 2008-08-20 | 2011-06-14 | Asante Solutions, Inc. | Infusion pump systems and methods |
| US9561324B2 (en) | 2013-07-19 | 2017-02-07 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
| WO2015047870A1 (en) | 2013-09-26 | 2015-04-02 | Companion Medical, Inc. | System for administering a medicament |
| CN105792751B (zh) | 2013-11-27 | 2019-07-05 | 雅培糖尿病护理公司 | 用于修正基于永久rom的编程的系统和方法 |
| EP3659651A3 (en) | 2014-07-10 | 2020-10-14 | Companion Medical, Inc. | Medicine administering system including injection pen and companion device |
| WO2016081620A1 (en) | 2014-11-19 | 2016-05-26 | Abbott Diabetes Care Inc. | Systems, devices, and methods for revising or supplementing rom-based rf commands |
| WO2017091624A1 (en) | 2015-11-24 | 2017-06-01 | Insulet Corporation | Wearable automated medication delivery system |
| HK1257246A1 (zh) | 2016-01-13 | 2019-10-18 | Bigfoot Biomedical, Inc. | 糖尿病管理系统的用户界面 |
| HK1257093A1 (zh) | 2016-01-14 | 2019-10-11 | Bigfoot Biomedical, Inc. | 调整胰岛素输送速率 |
| US10610643B2 (en) | 2016-01-14 | 2020-04-07 | Bigfoot Biomedical, Inc. | Occlusion resolution in medication delivery devices, systems, and methods |
| EP3407940A4 (en) | 2016-01-29 | 2019-09-04 | Companion Medical, Inc. | PURPOSES OF AUTOMATIC DRUG DISPOSAL |
| US12383166B2 (en) | 2016-05-23 | 2025-08-12 | Insulet Corporation | Insulin delivery system and methods with risk-based set points |
| US20170348479A1 (en) | 2016-06-03 | 2017-12-07 | Bryan Choate | Adhesive system for drug delivery device |
| CA3037432A1 (en) | 2016-12-12 | 2018-06-21 | Bigfoot Biomedical, Inc. | Alarms and alerts for medication delivery devices and related systems and methods |
| CN110574414B (zh) * | 2016-12-27 | 2023-04-04 | 株式会社电装 | 用于微定位传感器通信的系统和方法 |
| US10881793B2 (en) | 2017-01-13 | 2021-01-05 | Bigfoot Biomedical, Inc. | System and method for adjusting insulin delivery |
| US10610644B2 (en) | 2017-01-13 | 2020-04-07 | Bigfoot Biomedical, Inc. | Insulin delivery methods, systems and devices |
| US11027063B2 (en) | 2017-01-13 | 2021-06-08 | Bigfoot Biomedical, Inc. | Insulin delivery methods, systems and devices |
| US10500334B2 (en) | 2017-01-13 | 2019-12-10 | Bigfoot Biomedical, Inc. | System and method for adjusting insulin delivery |
| US10758675B2 (en) | 2017-01-13 | 2020-09-01 | Bigfoot Biomedical, Inc. | System and method for adjusting insulin delivery |
| WO2018227163A1 (en) | 2017-06-09 | 2018-12-13 | Companion Medical, Inc. | Intelligent medication delivery systems and methods |
| WO2019075352A1 (en) | 2017-10-12 | 2019-04-18 | Companion Medical, Inc. | INTELLIGENT DRUG DELIVERY SYSTEMS AND METHODS OF RECOMMENDATION AND DOSE MANAGEMENT |
| AU2018362257B2 (en) | 2017-10-30 | 2023-01-12 | Dexcom, Inc. | Diabetes management partner interface for wireless communication of analyte data |
| US11197964B2 (en) | 2017-12-12 | 2021-12-14 | Bigfoot Biomedical, Inc. | Pen cap for medication injection pen having temperature sensor |
| US11083852B2 (en) | 2017-12-12 | 2021-08-10 | Bigfoot Biomedical, Inc. | Insulin injection assistance systems, methods, and devices |
| US11077243B2 (en) | 2017-12-12 | 2021-08-03 | Bigfoot Biomedical, Inc. | Devices, systems, and methods for estimating active medication from injections |
| US11116899B2 (en) | 2017-12-12 | 2021-09-14 | Bigfoot Biomedical, Inc. | User interface for diabetes management systems and devices |
| US10987464B2 (en) | 2017-12-12 | 2021-04-27 | Bigfoot Biomedical, Inc. | Pen cap for insulin injection pens and associated methods and systems |
| US11464459B2 (en) | 2017-12-12 | 2022-10-11 | Bigfoot Biomedical, Inc. | User interface for diabetes management systems including flash glucose monitor |
| WO2019118531A2 (en) | 2017-12-12 | 2019-06-20 | Bigfoot Biomedical, Inc. | Therapy assist information and/or tracking device and related methods and systems |
| US10752209B2 (en) * | 2018-02-12 | 2020-08-25 | FELL Technology AS | System and method for wirelessly linking electronic components and/or sensors using sub-1 GHz frequencies (700-1000 MHz) for long range, robustness in wet environment and highly resistant to wireless noise |
| US10388412B1 (en) * | 2018-03-29 | 2019-08-20 | Reciprocal Labs Corporation | Decreased latency wireless communication for use with medicament devices |
| USD928199S1 (en) | 2018-04-02 | 2021-08-17 | Bigfoot Biomedical, Inc. | Medication delivery device with icons |
| WO2019213608A1 (en) | 2018-05-04 | 2019-11-07 | Dexcom, Inc. | Systems and methods relating to an analyte sensor system having a battery located within a disposable base |
| US11664107B2 (en) | 2018-05-08 | 2023-05-30 | Medtronic Minimed, Inc. | Intelligent medication delivery systems and methods using a prescription-regulated software application |
| US10898653B2 (en) | 2018-05-08 | 2021-01-26 | Companion Medical, Inc. | Intelligent medication delivery systems and methods for dose setting and dispensing monitoring |
| USD893020S1 (en) | 2018-05-11 | 2020-08-11 | Companion Medical, Inc. | Injection pen |
| US20190385728A1 (en) * | 2018-06-18 | 2019-12-19 | Bigfoot Biomedical, Inc. | Presenting insulin therapy setting recommendations associated with a therapy insight for a person with diabetes (pwd) and related methods |
| US11587663B2 (en) | 2018-06-20 | 2023-02-21 | Medtronic Minimed, Inc. | Intelligent medication delivery systems and methods for medicine dose calculation and reporting |
| USD892819S1 (en) | 2018-06-20 | 2020-08-11 | Companion Medical, Inc. | Display screen with graphical user interface |
| JP7307147B2 (ja) | 2018-07-17 | 2023-07-11 | インスレット コーポレイション | 薬剤送出ポンプ用の低い起動力を有するバルブ |
| WO2020056001A1 (en) * | 2018-09-11 | 2020-03-19 | Senseonics, Incorporated | An analyte monitoring system |
| US11882438B2 (en) * | 2018-10-29 | 2024-01-23 | Zorday IP, LLC | Network-enabled electronic cigarette |
| US12205699B1 (en) | 2018-10-30 | 2025-01-21 | Bigfoot Biomedical, Inc. | Method of pairing therapy devices using shared secrets, and related systems, methods and devices |
| USD920343S1 (en) | 2019-01-09 | 2021-05-25 | Bigfoot Biomedical, Inc. | Display screen or portion thereof with graphical user interface associated with insulin delivery |
| CN109806002B (zh) * | 2019-01-14 | 2021-02-23 | 微创(上海)医疗机器人有限公司 | 一种手术机器人 |
| US11948671B2 (en) | 2019-04-11 | 2024-04-02 | Medtronic Minimed, Inc. | Intelligent accessories for medicine dispensing device |
| US11135973B2 (en) * | 2019-04-12 | 2021-10-05 | Akaisha Pinckney | Driver alert system to prevent abandonment of a person or an animal in a vehicle and components thereof |
| US11666254B2 (en) * | 2019-05-17 | 2023-06-06 | Senseonics, Incorporated | Interoperability validation in an analyte monitoring system |
| WO2020242964A1 (en) | 2019-05-29 | 2020-12-03 | Dexcom, Inc. | System and method for wireless communication of analyte data |
| US11484210B1 (en) * | 2019-06-20 | 2022-11-01 | Waleed Bahaa El Deen Abdul Raheem Ahmed | Methods and systems for early detection of diabetes and advising those considered pre diabetic or diabetic |
| DE102019118965A1 (de) * | 2019-07-12 | 2021-01-14 | Workaround Gmbh | Nebengerät für ein Sensor- und/oder Informationssystem sowie Sensor- und/oder Informationssystem |
| US11957876B2 (en) | 2019-07-16 | 2024-04-16 | Beta Bionics, Inc. | Glucose control system with automated backup therapy protocol generation |
| DE112020003392T5 (de) | 2019-07-16 | 2022-05-19 | Beta Bionics, Inc. | Blutzuckerkontrollsystem |
| CA3146872A1 (en) | 2019-07-16 | 2021-01-21 | Beta Bionics, Inc. | Blood glucose control system |
| US20210060244A1 (en) * | 2019-08-28 | 2021-03-04 | Medtronic Minimed, Inc. | Method and system for verifying whether a non-medical client device is operating correctly with a medical device controlled by the non-medical client device and causing a notification to be generated |
| EP4042441A4 (en) * | 2019-10-04 | 2023-10-11 | Beta Bionics, Inc. | GLUCOSE REGULATION SYSTEM |
| CN114901125A (zh) * | 2019-11-15 | 2022-08-12 | 德克斯康公司 | 评估预测数据与相应的接收数据的差异的联合状态估计预测 |
| BR102020003529A2 (pt) * | 2020-02-20 | 2021-08-31 | Nilton Braz Giraldelli | Sistema para interpretação da medição de bioanalitos |
| BR102020005234A2 (pt) * | 2020-03-16 | 2021-09-28 | Nilton Braz Giraldelli | Sistema para interpretação e gerenciamento da medição de bioanalitos |
| USD977502S1 (en) | 2020-06-09 | 2023-02-07 | Insulet Corporation | Display screen with graphical user interface |
| US11851205B2 (en) | 2020-07-06 | 2023-12-26 | Honeywell International Inc. | Air quality monitoring |
| US11635312B2 (en) | 2020-07-06 | 2023-04-25 | Honeywell International Inc. | Systems and methods for remote sensor calibration |
| SE546662C2 (en) * | 2020-07-09 | 2025-01-14 | Pink Nectarine Health Ab | Method and system for monitoring a plurality of wearable devices in a self-organizing network |
| AU2021333768B2 (en) | 2020-08-27 | 2025-01-02 | Insulet Corporation | Wearable micro-dosing drug delivery device |
| US20220126017A1 (en) * | 2020-10-23 | 2022-04-28 | Insulet Corporation | Body conforming wearable device for providing output and input for a drug delivery system |
| US20220189603A1 (en) | 2020-12-07 | 2022-06-16 | Beta Bionics, Inc. | Medicament pumps and control systems for managing glucose control therapy data of a subject |
| CA3201977A1 (en) * | 2020-12-18 | 2022-06-23 | Insulet Corporation | Scheduling of medicament bolus deliveries by a medicament delivery device at future dates and times with a computing device |
| EP4262921A1 (en) | 2020-12-18 | 2023-10-25 | Insulet Corporation | Adhesive pad with a metallic coil for securing an on-body medical device |
| WO2022147985A1 (en) * | 2021-01-05 | 2022-07-14 | Medtrum Technologies Inc. | A skin patch drug infusion device |
| US12491310B2 (en) | 2021-01-12 | 2025-12-09 | Insulet Corporation | Wearable drug delivery device with removal element |
| US11747859B2 (en) * | 2021-03-16 | 2023-09-05 | Shailesh Nirgudkar | Personal safety headband |
| US12465686B2 (en) | 2021-03-25 | 2025-11-11 | Beta Bionics, Inc. | Emergency medicament dose control |
| KR102543830B1 (ko) * | 2021-05-24 | 2023-06-20 | 주식회사 지투이 | 인슐린펌프 |
| US12496398B2 (en) | 2021-05-28 | 2025-12-16 | Insulet Corporation | Threshold based automatic glucose control response |
| EP4101482A1 (en) | 2021-06-07 | 2022-12-14 | Insulet Corporation | Exercise safety prediction based on physiological conditions |
| US11701473B2 (en) | 2021-06-23 | 2023-07-18 | Medtronic Minimed, Inc. | Reusable injection pens |
| US20220409053A1 (en) * | 2021-06-23 | 2022-12-29 | Abbott Diabetes Care Inc. | Medical monitoring systems with cloud communication interface |
| EP4113533A3 (en) * | 2021-06-30 | 2023-03-29 | Insulet Corporation | Transitions to replacement on-body medical devices from expiring on-body medical devices that avoid downtime |
| US12495042B2 (en) * | 2021-08-16 | 2025-12-09 | Capital One Services, Llc | Systems and methods for resetting an authentication counter |
| CN118102975A (zh) * | 2021-10-11 | 2024-05-28 | 雅培糖尿病护理公司 | 用于在分析传感器与外部装置之间通信的系统、装置和方法 |
| WO2023069914A1 (en) * | 2021-10-22 | 2023-04-27 | Dexcom, Inc. | Proximity-based data access authentication and authorization in an analyte monitoring system |
| US20240122542A1 (en) * | 2022-10-13 | 2024-04-18 | Guardian Watch Inc. LLC | Wearable device |
| EP4609404A1 (en) * | 2022-10-24 | 2025-09-03 | Abbott Diabetes Care Inc. | Facilitating persistent connection to remote analyte monitoring systems |
| CA3275991A1 (en) | 2023-01-06 | 2024-07-11 | Insulet Corporation | Automatic or manual administration of meal boluses with subsequent automatic relaxation of safety constraints |
| WO2025117463A1 (en) * | 2023-11-27 | 2025-06-05 | Tandem Diabetes Care, Inc. | Adaptive delivery profiles for automated insulin delivery treatment system |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120096451A1 (en) | 2010-10-15 | 2012-04-19 | Roche Diagnostics Operations, Inc. | Firmware update in a medical device with multiple processors |
| US20140369268A1 (en) | 2013-06-15 | 2014-12-18 | Olympus Corporation | Flexible reservation-based mac for wireless body area networks |
| JP2017503619A (ja) | 2013-11-07 | 2017-02-02 | デックスコム・インコーポレーテッド | 分析物値の伝送及び連続的監視のためのシステム及び方法 |
| US20170181628A1 (en) | 2015-12-28 | 2017-06-29 | Dexcom, Inc. | Intelligent wireless communications for continuous analyte monitoring |
| US20170189614A1 (en) | 2016-01-05 | 2017-07-06 | Bigfoot Biomedical, Inc. | Operating multi-modal medicine delivery systems |
| US20170281000A1 (en) | 2016-03-31 | 2017-10-05 | Dexcom, Inc. | Systems and methods for display device and sensor electronics unit communication |
Family Cites Families (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2106280C (en) | 1992-09-30 | 2000-01-18 | Yennun Huang | Apparatus and methods for fault-tolerant computing employing a daemon monitoring process and fault-tolerant library to provide varying degrees of fault tolerance |
| US6001067A (en) | 1997-03-04 | 1999-12-14 | Shults; Mark C. | Device and method for determining analyte levels |
| US6119028A (en) | 1997-10-20 | 2000-09-12 | Alfred E. Mann Foundation | Implantable enzyme-based monitoring systems having improved longevity due to improved exterior surfaces |
| US6081736A (en) | 1997-10-20 | 2000-06-27 | Alfred E. Mann Foundation | Implantable enzyme-based monitoring systems adapted for long term use |
| US6175752B1 (en) | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
| US6424847B1 (en) | 1999-02-25 | 2002-07-23 | Medtronic Minimed, Inc. | Glucose monitor calibration methods |
| US8260393B2 (en) | 2003-07-25 | 2012-09-04 | Dexcom, Inc. | Systems and methods for replacing signal data artifacts in a glucose sensor data stream |
| US8010174B2 (en) | 2003-08-22 | 2011-08-30 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
| US9247901B2 (en) | 2003-08-22 | 2016-02-02 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
| US7294105B1 (en) | 2002-09-03 | 2007-11-13 | Cheetah Omni, Llc | System and method for a wireless medical communication system |
| US7460898B2 (en) | 2003-12-05 | 2008-12-02 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| US7276029B2 (en) | 2003-08-01 | 2007-10-02 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US7519408B2 (en) | 2003-11-19 | 2009-04-14 | Dexcom, Inc. | Integrated receiver for continuous analyte sensor |
| US20080119703A1 (en) | 2006-10-04 | 2008-05-22 | Mark Brister | Analyte sensor |
| US7591801B2 (en) | 2004-02-26 | 2009-09-22 | Dexcom, Inc. | Integrated delivery device for continuous glucose sensor |
| US8275437B2 (en) | 2003-08-01 | 2012-09-25 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US20070208245A1 (en) | 2003-08-01 | 2007-09-06 | Brauker James H | Transcutaneous analyte sensor |
| US7774145B2 (en) | 2003-08-01 | 2010-08-10 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8233959B2 (en) | 2003-08-22 | 2012-07-31 | Dexcom, Inc. | Systems and methods for processing analyte sensor data |
| EP2301428B1 (en) | 2003-12-09 | 2016-11-30 | Dexcom, Inc. | Signal processing for continuous analyte sensor |
| US7647097B2 (en) * | 2003-12-29 | 2010-01-12 | Braingate Co., Llc | Transcutaneous implant |
| US7946984B2 (en) | 2004-07-13 | 2011-05-24 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8374668B1 (en) | 2007-10-23 | 2013-02-12 | Abbott Diabetes Care Inc. | Analyte sensor with lag compensation |
| WO2007120381A2 (en) | 2006-04-14 | 2007-10-25 | Dexcom, Inc. | Analyte sensor |
| US20070255125A1 (en) | 2006-04-28 | 2007-11-01 | Moberg Sheldon B | Monitor devices for networked fluid infusion systems |
| US8579853B2 (en) * | 2006-10-31 | 2013-11-12 | Abbott Diabetes Care Inc. | Infusion devices and methods |
| US20090076350A1 (en) * | 2007-09-14 | 2009-03-19 | Corventis, Inc. | Data Collection in a Multi-Sensor Patient Monitor |
| CA2715628A1 (en) | 2008-02-21 | 2009-08-27 | Dexcom, Inc. | Systems and methods for processing, transmitting and displaying sensor data |
| US8769257B2 (en) | 2008-12-23 | 2014-07-01 | Intel Corporation | Method and apparatus for extending transport layer security protocol for power-efficient wireless security processing |
| US8344847B2 (en) | 2009-07-09 | 2013-01-01 | Medtronic Minimed, Inc. | Coordination of control commands in a medical device system having at least one therapy delivery device and at least one wireless controller device |
| US11210611B2 (en) * | 2011-12-21 | 2021-12-28 | Deka Products Limited Partnership | System, method, and apparatus for electronic patient care |
| US9041730B2 (en) | 2010-02-12 | 2015-05-26 | Dexcom, Inc. | Receivers for analyzing and displaying sensor data |
| US8781550B2 (en) * | 2010-10-15 | 2014-07-15 | Roche Diagnostics Operations, Inc. | Communication protocol that supports structured collection procedures used in diabetes care |
| JP5799883B2 (ja) * | 2011-06-16 | 2015-10-28 | コニカミノルタ株式会社 | 接続制御装置、情報処理装置、画像形成装置、携帯型移動端末、情報処理システム、接続制御装置の制御方法、及び接続制御装置の制御プログラム |
| EP2723229B1 (en) | 2011-06-23 | 2018-09-26 | University Of Virginia Patent Foundation | Unified platform for monitoring and control of blood glucose levels in diabetic patients |
| US9152784B2 (en) | 2012-04-18 | 2015-10-06 | Mcafee, Inc. | Detection and prevention of installation of malicious mobile applications |
| US20140012511A1 (en) | 2012-07-09 | 2014-01-09 | Dexcom, Inc. | Systems and methods for leveraging smartphone features in continuous glucose monitoring |
| GB201214976D0 (en) | 2012-08-22 | 2012-10-03 | Connect In Ltd | Monitoring system |
| CN102843236B (zh) | 2012-09-12 | 2014-12-10 | 飞天诚信科技股份有限公司 | 一种动态口令的生成及认证方法与系统 |
| US20140235984A1 (en) * | 2013-02-01 | 2014-08-21 | Edwards Lifesciences Corporation | System for a blood analyte sensor |
| US20140324445A1 (en) * | 2013-04-26 | 2014-10-30 | Roche Diagnostics Operations, Inc. | Diabetes management system medical device usage statistics |
| AU2014370122A1 (en) | 2013-12-27 | 2016-07-07 | Abbott Diabetes Care Inc. | Application interface and display control in an analyte monitoring environment |
| KR102167646B1 (ko) * | 2014-04-01 | 2020-10-19 | 삼성전자주식회사 | 프레임 정보를 제공하는 전자 장치 및 방법 |
| WO2015179526A1 (en) | 2014-05-21 | 2015-11-26 | Abbott Diabetes Care Inc. | Management of multiple devices within an analyte monitoring environment |
| ES2921199T3 (es) | 2014-08-01 | 2022-08-19 | Becton Dickinson Co | Dispositivo de inyección con monitorización continua de glucosa |
| US10200443B2 (en) * | 2014-08-22 | 2019-02-05 | Microsoft Technology Licensing, Llc | Remote user interface event notification |
| US9626336B2 (en) * | 2014-08-22 | 2017-04-18 | Microsoft Technology Licensing, Llc | Remote management of a graphical user interface |
| WO2016086033A2 (en) | 2014-11-25 | 2016-06-02 | Abbott Diabetes Care Inc. | Analyte monitoring systems and related test and monitoring methods |
| KR20160071826A (ko) * | 2014-12-12 | 2016-06-22 | 삼성전자주식회사 | 무선 네트워크 연결 방법 및 그 전자 장치 및 방법 |
| US9956393B2 (en) * | 2015-02-24 | 2018-05-01 | Elira, Inc. | Systems for increasing a delay in the gastric emptying time for a patient using a transcutaneous electro-dermal patch |
| US10335302B2 (en) * | 2015-02-24 | 2019-07-02 | Elira, Inc. | Systems and methods for using transcutaneous electrical stimulation to enable dietary interventions |
| US10424219B2 (en) | 2015-05-07 | 2019-09-24 | Dexcom, Inc. | System and method for educating users, including responding to patterns |
| US10095834B2 (en) | 2015-05-08 | 2018-10-09 | YC Wellness, Inc. | Integration platform and application interfaces for remote data management and security |
| JP2018524718A (ja) * | 2015-06-25 | 2018-08-30 | ガンブロ・ルンディア・エービーGambro Lundia Ab | 分散データベースを有する医療装置システム及び方法 |
| EP3138488B1 (en) | 2015-09-02 | 2019-06-05 | Roche Diabetes Care GmbH | Sensor module and kit for determining an analyte concentration |
| EP3373810A4 (en) * | 2016-01-14 | 2020-03-25 | Bigfoot Biomedical, Inc. | DIABETES MANAGEMENT SYSTEM |
| SI3261357T1 (sl) | 2016-06-23 | 2019-03-29 | Roche Diabetes Care Gmbh | Postopek za brezžično podatkovno komunikacijo med senzorskim sistemom in sprejemnikom, sistem za brezžično podatkovno komunikacijo in računalniški programski produkt |
| US10638962B2 (en) | 2016-06-29 | 2020-05-05 | Glysens Incorporated | Bio-adaptable implantable sensor apparatus and methods |
| US9905063B1 (en) | 2016-08-10 | 2018-02-27 | Elwha Llc | Systems and methods for individual identification and authorization utilizing conformable electronics |
| CN113398380B (zh) * | 2016-09-27 | 2023-07-28 | 比格福特生物医药公司 | 药物注射和疾病管理系统、设备和方法 |
| US20180121610A1 (en) | 2016-10-28 | 2018-05-03 | Always In Touch, Inc. | Selecting a healthcare data processing approach |
| WO2018118822A1 (en) | 2016-12-20 | 2018-06-28 | Abbott Diabetes Care Inc. | Systems, devices and methods for wireless communications in analyte monitoring devices |
| US20170173262A1 (en) * | 2017-03-01 | 2017-06-22 | François Paul VELTZ | Medical systems, devices and methods |
| US20180279911A1 (en) | 2017-03-28 | 2018-10-04 | Glysens Incorporated | Analyte sensor user interface apparatus and methods |
| USD839294S1 (en) | 2017-06-16 | 2019-01-29 | Bigfoot Biomedical, Inc. | Display screen with graphical user interface for closed-loop medication delivery |
| AU2018362257B2 (en) | 2017-10-30 | 2023-01-12 | Dexcom, Inc. | Diabetes management partner interface for wireless communication of analyte data |
| CN111971982A (zh) | 2018-02-05 | 2020-11-20 | 雅培糖尿病护理公司 | 用于电子装置之间的节能无线通信的系统、装置和方法 |
| CA3253956A1 (en) | 2022-03-18 | 2023-09-21 | Dexcom, Inc. | CONTINUOUS MULTI-ANALYTICAL SENSOR SYSTEMS |
-
2018
- 2018-10-24 AU AU2018362257A patent/AU2018362257B2/en active Active
- 2018-10-24 EP EP23184160.2A patent/EP4236548A1/en active Pending
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- 2018-10-24 US US16/169,886 patent/US11363025B2/en active Active
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- 2018-10-24 US US16/169,661 patent/US11153317B2/en active Active
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- 2023-04-05 AU AU2023202112A patent/AU2023202112B2/en active Active
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- 2023-10-09 US US18/483,473 patent/US12047381B2/en active Active
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-
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- 2025-05-08 AU AU2025203318A patent/AU2025203318A1/en active Pending
- 2025-06-24 JP JP2025106414A patent/JP2025157252A/ja active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120096451A1 (en) | 2010-10-15 | 2012-04-19 | Roche Diagnostics Operations, Inc. | Firmware update in a medical device with multiple processors |
| US20140369268A1 (en) | 2013-06-15 | 2014-12-18 | Olympus Corporation | Flexible reservation-based mac for wireless body area networks |
| JP2017503619A (ja) | 2013-11-07 | 2017-02-02 | デックスコム・インコーポレーテッド | 分析物値の伝送及び連続的監視のためのシステム及び方法 |
| US20170181628A1 (en) | 2015-12-28 | 2017-06-29 | Dexcom, Inc. | Intelligent wireless communications for continuous analyte monitoring |
| US20170189614A1 (en) | 2016-01-05 | 2017-07-06 | Bigfoot Biomedical, Inc. | Operating multi-modal medicine delivery systems |
| US20170281000A1 (en) | 2016-03-31 | 2017-10-05 | Dexcom, Inc. | Systems and methods for display device and sensor electronics unit communication |
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