JP7272952B2 - 内因性および起源ＤＮＡのワンショットガイドＲＮＡ（ｏｇＲＮＡ）標的化のためのシステムおよび方法 - Google Patents

内因性および起源ＤＮＡのワンショットガイドＲＮＡ（ｏｇＲＮＡ）標的化のためのシステムおよび方法 Download PDF

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JP7272952B2
JP7272952B2 JP2019530105A JP2019530105A JP7272952B2 JP 7272952 B2 JP7272952 B2 JP 7272952B2 JP 2019530105 A JP2019530105 A JP 2019530105A JP 2019530105 A JP2019530105 A JP 2019530105A JP 7272952 B2 JP7272952 B2 JP 7272952B2
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アリ イー． フリートラント，
ハリハラン ジャヤラム，
ベレット イーサン スタインバーグ，
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エディタス・メディシン、インコーポレイテッド
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    • C12N2810/10—Vectors comprising a non-peptidic targeting moiety

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JP2019530105A 2016-12-05 2017-12-05 内因性および起源ＤＮＡのワンショットガイドＲＮＡ（ｏｇＲＮＡ）標的化のためのシステムおよび方法 Active JP7272952B2 (ja)

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JP2022208855A JP2023052089A (ja) 2016-12-05 2022-12-26 内因性および起源ＤＮＡのワンショットガイドＲＮＡ（ｏｇＲＮＡ）標的化のためのシステムおよび方法

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US201662430154P 2016-12-05 2016-12-05
US62/430,154 2016-12-05
US201762503640P 2017-05-09 2017-05-09
US62/503,640 2017-05-09
PCT/US2017/064720 WO2018106693A1 (en) 2016-12-05 2017-12-05 SYSTEMS AND METHODS FOR ONE-SHOT GUIDE RNA (ogRNA) TARGETING OF ENDOGENOUS AND SOURCE DNA

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JP2022208855A Withdrawn JP2023052089A (ja) 2016-12-05 2022-12-26 内因性および起源ＤＮＡのワンショットガイドＲＮＡ（ｏｇＲＮＡ）標的化のためのシステムおよび方法

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CN (1) CN110168084A (https=)
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CN115491373A (zh) * 2015-10-30 2022-12-20 爱迪塔斯医药公司 治疗单纯疱疹病毒的crispr/cas相关方法及组合物
US11866726B2 (en) 2017-07-14 2024-01-09 Editas Medicine, Inc. Systems and methods for targeted integration and genome editing and detection thereof using integrated priming sites
CA3082450A1 (en) 2017-11-21 2019-05-31 Crispr Therapeutics Ag Materials and methods for treatment of autosomal dominant retinitis pigmentosa
WO2019118875A1 (en) * 2017-12-15 2019-06-20 Ou Li Crispr-mediated genome editing with vectors
EP3823633A4 (en) 2018-06-29 2023-05-03 Editas Medicine, Inc. SYNTHETIC LEAD MOLECULES, COMPOSITIONS AND METHODS RELATED THERETO
US12227547B2 (en) 2018-09-10 2025-02-18 The Regents Of The University Of California Modulators of CAS9 polypeptides and methods of use thereof
CA3130515A1 (en) 2019-02-25 2020-09-03 Editas Medicine, Inc. Crispr/rna-guided nuclease-related methods and compositions for treating rho-associated autosomal-dominant retinitis pigmentosa (adrp)
SG11202109741VA (en) * 2019-03-12 2021-10-28 Crispr Therapeutics Ag Novel high fidelity rna-programmable endonuclease systems and uses thereof
MA56393A (fr) * 2019-06-28 2022-05-04 Bayer Healthcare Llc Matériels et méthodes de régulation de l'édition de gènes
WO2021053582A1 (en) * 2019-09-18 2021-03-25 Crispr Therapeutics Ag All-in-one self inactivating crispr vectors
WO2021062201A1 (en) * 2019-09-25 2021-04-01 Spotlight Therapeutics Compositions and methods for nucleoprotein targeting and expression
CA3180775A1 (en) * 2020-05-29 2021-12-16 Regents Of The University Of Minnesota Copolymers for intracellular therapeutic nucleic acid payload delivery
AU2021391783A1 (en) * 2020-12-03 2023-06-22 Scribe Therapeutics Inc. Compositions and methods for the targeting of bcl11a
WO2022221741A1 (en) 2021-04-16 2022-10-20 Editas Medicine, Inc. Crispr/rna-guided nuclease-related methods and compositions for treating rho-associated autosomal-dominant retinitis pigmentosa (adrp)
WO2025179057A1 (en) * 2024-02-21 2025-08-28 The Regents Of The University Of California In vivo modification of cell genomes

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US12264331B2 (en) 2025-04-01
JP2019536462A (ja) 2019-12-19
US10494649B2 (en) 2019-12-03
US20230416787A1 (en) 2023-12-28
JP2023052089A (ja) 2023-04-11
AU2017373797A1 (en) 2019-06-20
MX2024002327A (es) 2024-03-07
US9963719B1 (en) 2018-05-08
MX2019006475A (es) 2019-09-26
US11692205B2 (en) 2023-07-04
US10006054B1 (en) 2018-06-26
EP3548614A1 (en) 2019-10-09
KR20190088555A (ko) 2019-07-26
US20180251792A1 (en) 2018-09-06
US11028411B2 (en) 2021-06-08
US20220017927A1 (en) 2022-01-20
KR102604903B1 (ko) 2023-11-21
AU2017373797B2 (en) 2024-08-29
CA3046076A1 (en) 2018-06-14
US20200056208A1 (en) 2020-02-20
WO2018106693A1 (en) 2018-06-14
CN110168084A (zh) 2019-08-23
US20180201956A1 (en) 2018-07-19

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