JP7158645B2 - specimen collection swab - Google Patents

Description

The present invention relates to specimen collection swabs.

Swabs are used to collect biological specimens in the field of clinical and diagnostic analysis. Such a swab has a sample-collecting portion made of a fibrous body made of natural fibers or synthetic fibers at the tip of a rod, and is exemplified by a cotton swab.

For example, an influenza virus infection test is performed by collecting mucus from the nasal cavity or throat using a cotton swab and determining the presence or absence of the influenza virus in the obtained mucus (Patent Document 1). However, since cotton, rayon, etc. are hydrophilic, there is a problem that the amount of collected specimen released is small. As means for solving such problems, there is known a method of removing oil from the fibers used for the cotton ball (Patent Document 2). A method of flocking cotton balls is also known (Patent Document 3).

Further, there is also known a technique of forming a specimen collecting portion with a nonwoven fabric composed of loop-shaped fibers for the purpose of collecting a sufficient amount of specimen for testing (Patent Document 4).

Japanese Patent Publication No. 2002-508193 JP-A-2003-315218 Japanese Patent Publication No. 2007-523663 JP 2017-015610 A

However, the swabs described in Patent Documents 1 to 3 are unstable in the amount of sample collected, have a low release efficiency of the collected sample, and furthermore cause pain and discomfort to the subject due to the material and shape of the sample collection part. There was a problem of giving

In addition, the swab described in Patent Document 4 is weak against the force of pulling out the nonwoven fabric in the extension direction of the rod because the sample collection part is formed of a nonwoven fabric having an extremely high porosity. Some parts fell off. If the cotton ball part falls off from the rod when collecting mucus from the nasal cavity or throat, it may cause a serious medical accident. Such a characteristic is hereinafter referred to as "drop-off avoidance".

Known methods for imparting the ability to prevent the sample collection swab from falling off include, for example, the use of an adhesive, the method of welding with heat, and the method of tying with a string, etc., when attaching the fibrous body as the sample collection part to the rod. It is However, in the method using an adhesive, the adhesive infiltrates into the fibrous body, lowering the porosity of the fibrous body and sometimes making it impossible to collect the required amount of sample. In addition, the method of welding with heat also reduces the porosity of the cotton ball portion because the fibrous body is used for welding. Furthermore, in the method of tying with a string or the like, it is very difficult to tie the fibrous body with a string because the diameter of the rod used for the swab is small, and it is difficult to give the swab a satisfactory ability to prevent it from coming off. .

Accordingly, an object of the present invention is to stably collect a sufficient amount of biological specimen such as mucus from the nasal cavity, throat, etc. for examination without giving pain or discomfort to the subject. To provide a specimen-collecting swab with high release efficiency of a collected specimen, and to provide a specimen-collection swab with high drop-off avoidance.

The inventors of the present invention found that the above problems can be solved by using a specimen collection swab that includes a rod and a bag-like fibrous body wrapped around the tip region of the rod, and have developed the present invention. Completed.

That is, the present invention includes a rod having a tip region portion having a distal end portion, a flange portion, and a return piece portion positioned therebetween and having a retaining tip, and wrapping the tip region portion of the rod. A sample collection swab comprising: a bag-like fibrous body that

Further, according to the present invention, there is provided a specimen collection swab comprising a rod and a bag-like fibrous body wrapped around a tip region of the rod, wherein the bag-like fibrous body is formed of nonwoven fabric. and the nonwoven fabric has a basis weight of 110 to 130 g/m ² .

In the specimen collection swab, the distance from the rod to the retaining tip is preferably longer than the distance from the rod to the extension end of the flange portion.

In the specimen collection swab, it is preferable that the fibrous body is wrapped around the rod without being fixed with an adhesive.

The sample-collecting swab preferably has a fibrous body made of polyethylene terephthalate.

Said specimen collection swab is preferably for biological specimen collection.

The specimen collection swab of the present invention can stably collect a sufficient amount of biological specimen such as mucus from the nasal cavity, throat, etc. for examination without causing pain or discomfort to the subject. It is useful in the fields of clinical and diagnostic analysis because it has a high release efficiency of the sample and a high drop-off avoidance.

An example of a rod and specimen collection swab is shown. 1 shows an example of a tip region of a rod and a bag-like fibrous body wrapped around the tip region. The device used in the evaluation of Examples is shown.

<Specimen collection swab>
A specimen-collecting swab according to the present invention is characterized by comprising a rod and a bag-like fibrous body wrapped around a tip region of the rod.

A first aspect of the specimen collection swab in the present invention includes a rod having a distal end region portion having a distal end portion, a flange portion, and a return piece portion positioned between them and having a retaining tip, and the rod and a bag-like fibrous body wrapped around the tip region. A second aspect of the specimen-collecting swab of the present invention is a specimen-collecting swab comprising a rod and a bag-shaped fibrous body wrapped around a tip region of the rod, wherein the bag-shaped The fibrous body is formed of a nonwoven fabric, and the fabric weight of the nonwoven fabric is 110 to 130 g/m ² . The first aspect and the second aspect of the specimen collection swab according to the present invention may be collectively referred to as the "swab of the present invention".

An example of the swab of the present invention will be described with reference to FIGS. 1 and 2. FIG. (A) of FIG. 1 shows a rod (rod before attachment of a fiber body), and (B) of FIG. 1 shows a swab with a body. In FIGS. 1A and 1B, 1 indicates the handle, 2 the rod, 3 the distal end of the rod, and 4 the fibrous body, which is the specimen collecting portion.

(A) of FIG. 2 shows the tip region of the rod, and (B) of FIG. 2 shows the bag-like fibrous body wrapped around the tip region of the rod. In FIG. 2, 11 is the distal end portion, 12 is the return piece portion having the retaining tip, 13 is the retaining tip, 14 is the flange portion, and 15 is the fibrous body wrapped around the tip region of the rod. , and 16 indicates the bag opening of the fibrous body. As shown in the drawing, the return pieces having 12 retainer tips have a substantially triangular shape, one of which forms a pair with the other.

Since the swab of the first aspect has a rod of a specific shape, it exhibits a high ability to prevent falling off. In addition, since the swab of the second aspect includes a specific fibrous body as the sample-collecting portion, a sufficient amount of mucus, etc. for examination can be collected from the nasal cavity, throat, etc. without causing pain or discomfort to the subject. A constant amount of sample can be stably collected, and the sample is released with high efficiency.

[rod]
The shape of the rod is not particularly limited, but from the viewpoint of preventing the fiber body from falling off, it is preferable that the shape has a tip region portion having either one of a flange portion and a return piece portion having a retaining tip, It is more preferable to have a tip region portion having both a flange portion and a return piece portion having a retaining tip. If the rod has a tip region having both a flange and a barbed piece with a retaining tip, the barb with the retaining tip is located between the most distal portion and the flange, i.e. It is particularly preferable for the rod to have a distal end region portion having a distal end portion, a flange portion, and a return piece portion located therebetween and having a retaining tip, in order to exhibit high drop-off avoidance.

The flange portion exerts drop-off preventive properties by contacting the bag mouth portion of the fibrous body. That is, when a force to pull out the fibrous body is applied in the direction in which the rod extends toward the distal end (hereinafter, sometimes simply referred to as the "rod extending direction"), the bag mouth portion of the fibrous body touches the flange portion. The contact causes a stress in the direction opposite to the pull-out force, and as a result, the ability to avoid falling off is exhibited. Therefore, it is preferable that the flange portion has a width (the width in a longitudinal cross-sectional view passing through the central axis of the rod) that can come into contact with the bag mouth portion of the fibrous body. In addition, the shape of the flange portion is not particularly limited, but having a curved surface shape that forms an arc-shaped contour in a vertical cross-sectional view passing through the central axis of the rod, that is, a circular or substantially circular shape, is highly effective in preventing falling off. It is preferable in terms of being exhibited.

The return piece portion having the slip-off preventing tip exerts drop-off preventive properties by coming into contact with the interior of the bag and/or the mouth portion of the fibrous body. That is, when a force to pull out the fibrous body is applied in the extension direction of the rod, the inside of the bag and/or the bag mouth of the fibrous body come into contact with the return piece portion having the retaining tip, so that the pull-out force is applied. generates a stress in the opposite direction, and as a result, the ability to avoid falling off is exhibited. Therefore, it is necessary that the return piece portion having the retaining tip be provided with the retaining tip capable of contacting the inside of the bag and/or the bag opening of the fibrous body and exerting the stress. In addition, the shape of the return piece portion having the retainer tip is not particularly limited, but for example, a substantially triangular shape in which the retainer tip is oriented in the direction opposite to the direction in which the rod extends is recommended for high falling off. It is preferable in that avoidability is demonstrated. In addition, as shown in FIG. 2, two return pieces having retaining tips may exist on the surface of the rod, and one may be paired with the other, but is not limited to this. A mode in which 1 to 6 are present on the surface of the rod may be used.

As described above, when the tip region of the rod has a distal end portion, a flange portion, and a return piece portion positioned between them and having a retaining tip, the return piece portion having the flange portion and the retaining tip As compared with the case of having only one of the above, there is a tendency that high drop-off avoidance is exhibited. This is because when a force is applied to pull out the fibrous body in the extension direction of the rod, the flange portion comes into contact with the bag opening of the fibrous body and the retaining tip comes into contact with the inside of the bag of the fibrous body. The stress in the direction opposite to the force applied to the fibrous body is dispersed in the bag mouth portion of the fibrous body and the inside of the bag. This is considered to be due to the fact that no breakage occurred and no dropout from the rod occurred.

For this reason, the tip region of the rod has a distal end, a flange, and a return piece positioned therebetween and having a retaining tip, and furthermore, the distance from the rod to the retaining tip is If the length is longer than the length of the extended end of the flange portion, when a force is applied to pull out the fibrous body in the extension direction of the rod, the retaining tip can easily come into contact with the inside of the bag. Falling-avoidability is demonstrated.

Moreover, from the viewpoint of avoidance of falling off, it is preferable that the distal end portion and the bag bottom portion of the fibrous body are adhered to each other.

Although the shape of the tip of the rod is not particularly limited, it is preferably approximately spherical, for example. For example, when collecting mucus from the nasal cavity or throat, the tip of the swab may touch the nasal cavity or throat. .

The tip region of the rod refers to the portion that is wrapped around the fibrous body, and may have, for example, a tip, a return piece having a retaining tip, and a flange.

The rod may or may not have a handle to make it easier to hold. Also, the handle may be made of the same material as the rod, but is preferably the same.

The material of the rod is not particularly limited as long as it is a material generally used for swabs, and examples thereof include paper, wood, metal, and plastic. Among these, plastics are preferable from the viewpoint of workability, and examples thereof include vinyl chloride, polyethylene, polypropylene, polyester, polystyrene, polyamide, and polycarbonate.

Since the rod may be heated when the fibrous body is attached or when the swab is sterilized, it is preferable to use a material that does not melt depending on the heating temperature. The melting point of the rod is, for example, preferably 60° C. or higher, more preferably 80° C. or higher, still more preferably 100° C. or higher.

The cross-sectional shape of the rod is not particularly limited, and examples thereof include circular, triangular, quadrangular, hexagonal, and flat. Also, when the handle is provided on the rod, it may have the same shape, but it is particularly preferable that the cross section is a hexagonal cross section.

Although the length of the rod is not particularly limited, it is preferably 60 to 250 mm, more preferably 80 to 200 mm.

Although the length of the handle is not particularly limited, it is preferably 30 to 150 mm, more preferably 60 to 120 mm. Although the diameter of the handle is not particularly limited, it is preferably 0.4 to 10.0 mm, more preferably 1.0 to 5.0 mm. Here, the diameter of the handle refers to the longest diameter in the sectional view of the handle.

Although the length from the tip of the rod to the retaining tip is not particularly limited, it is, for example, 4 to 30 mm, more preferably 6 to 25 mm, further preferably 8 to 20 mm. In addition, the "tip of the rod" can be rephrased as "the tip of the most distal part of the rod".

Although the length from the tip of the rod to the flange portion is not particularly limited, it is, for example, 5 to 30 mm, more preferably 8 to 25 mm, still more preferably 10 to 20 mm.

The length from the retainer tip to the flange portion is not particularly limited, but is, for example, 0.3 to 10 mm, more preferably 0.5 to 5 mm, still more preferably 0.8 to 3 mm.

Although the thickness of the flange portion is not particularly limited, it is, for example, 0.1 to 3 mm, more preferably 0.2 to 2 mm, still more preferably 0.3 to 1 mm.

Although the diameter of the rod (rod in the tip region) is not particularly limited, it is preferably 0.3 to 2.5 mm, more preferably 0.4 to 2.0 mm. Here, the diameter of the rod refers to the longest diameter in the cross section of the rod.

The length from the surface of the rod to the retaining tip (the height of the retaining tip when the rod surface is the base) is not particularly limited, but is, for example, 0.1 to 5 mm, more preferably 0.2 to 0.2 mm. 3 mm, more preferably 0.3 to 1 mm.

Although the diameter of the flange portion is not particularly limited, it is, for example, 0.3 to 10 mm, more preferably 0.5 to 5 mm, still more preferably 0.8 to 3 mm.

[Fibrous body]
The fibrous body is not particularly limited as long as it has a bag-like shape and can be wrapped around the tip region of the rod. In the swab of the present invention, the fibrous body corresponds to the specimen collecting portion.

The fibrous body may be made of fibers such as polyester, polyamide, polypropylene, polyurethane, acrylic, rayon, carbon fiber, alginate, cotton, and silk, but is preferably made of polyester such as polyethylene terephthalate. .

Examples of the fibrous body include bag-shaped cloth such as woven fabric, knitted fabric (knitted fabric), lace, felt, and non-woven fabric. Among these, a bag-like non-woven fabric is preferable from the viewpoint of sample collection amount and release efficiency.

The non-woven fabric is not particularly limited, but it is formed into a web by a dry method, a wet method, a spunbond method, a meltblown method, an airlaid method, etc., and this web is subjected to an immersion method (chemical bond method), a spray method (chemical bond method), a thermal bond. entanglement method, needle punch method, spunlace method (hydroentanglement method) or the like. Among these, nonwoven fabrics produced by the spunlace method tend to increase the amount of specimens collected from the swab, increase the discharge efficiency of the collected specimens, and reduce the pain given to the subject.

Although the basis weight of the nonwoven fabric is not particularly limited, it is preferably 40 to 200 g/m ² , more preferably 80 to 160 g/m ² , still more preferably 100 to 140 g/m ² . Furthermore, when the basis weight of the non-woven fabric is 110 to 130 g/m ² , there is a tendency that the sample collection amount of the swab is improved and the discharge efficiency of the collected sample is increased.

The average diameter of the fibers forming the fibrous body is not particularly limited. be. When a nonwoven fabric is used, the fiber length is not particularly limited, but for example, the average fiber length is preferably 10 to 100 mm.

The method of attaching the fibrous body to the rod is not particularly limited, but for example, the cloth is folded in two, the rod is sandwiched between one side and the other side, and then the cloth is welded and melted to form a bag-like fibrous body. is preferred. The above method eliminates the need for welding and fusing the folds, which is effective in simplifying the work. In addition, since the fold portion becomes the tip portion of the fibrous body, the tip portion has a soft shape, which is effective in that it does not cause pain or discomfort to the subject.

The fibrous body may have its surface raised and fluffed. The method of raising the fabric includes an emery raising method using sandpaper and a clothing raising method. The raised period may be raised in advance on the nonwoven fabric, or may be performed after the cloth is attached to the rod.

The fibrous body may be fixed to the rod with an adhesive, or may be wrapped around the rod without being fixed with an adhesive.

When attaching the fibrous body to the rod via an adhesive, the type of adhesive is not particularly limited, but ethylene vinyl acetate-based, polyolefin-based, polyamide-based, synthetic rubber-based, acrylic-based, and polyurethane-based hot-melt adhesives can be used. Moreover, the form may be any of an organic solvent-soluble product, a water-soluble product, an emulsion, a solvent-free product, and the like. When an adhesive is used, it should be used in such an amount that it does not fill the voids in the fibrous body, and its viscosity should be such that it does not easily penetrate into the voids.

When fixing the fibrous body to the rod with an adhesive, the fixing may be performed by heating the adhesive. Heaters, ultrasonic waves, and lasers can be used as heating means.

The length of the fibrous body is not particularly limited as long as it can be wrapped around the tip region of the rod. is. The length of the fibrous body is the length along the rod, and can be rephrased as the length from the mouth of the bag to the bottom of the bag.

The bag opening of the fiber body preferably has a diameter smaller than that of the flange in order to prevent the bag from coming off in contact with the flange.

The swabs of the invention are preferably sterile. As a sterilization means, chemical sterilization by ethylene oxide gas, radiation sterilization, electron beam sterilization, or the like can be used. Dry heat sterilization by an autoclave is not preferable when a resin having a low melting point is used for the thermoplastic resin layer.

The swab of the present invention can stably collect a sufficient amount of biological specimen such as mucus from the nasal cavity, throat, etc. for examination without causing pain or discomfort to the subject. Since it has a high release efficiency and high drop-off avoidance, it can be used for collecting biological specimens (for collecting biological specimens), and is useful in the fields of clinical and diagnostic analysis.

Hereinafter, the present invention will be described more specifically with reference to examples. The present invention is not limited by these.

(Production Example 1: Production of rod)
Using an injection molding machine manufactured by Sumitomo Heavy Industries, polypropylene is melted at 180°C and poured into a mold. A rod having parts in this order was obtained. The shape of the tip region of the rod is the same as the shape shown in FIG. 1 mm, the thickness of the flange portion is 0.5 mm, the diameter of the nearly spherical body at the most distal end is 1.38 mm, the diameter of the rod (rod in the tip region) is 0.90 mm, the length from the surface of the rod to the retaining tip The length (the height of the retaining tip when the rod surface is the base) is 0.4 mm, the length from the rod surface to the retaining tip (the height of the retaining tip when the rod surface is the base) ) is 0.4 mm, the length along the rod of the return piece portion having the retaining tip (the length along the rod in the triangular shape) is 2.0 mm, the diameter of the flange portion is 1.5 mm, and the length of the handle is The length was 86 mm and the rod length was 152 mm.

(Production Example 2: Production of swab 1)
A non-woven fabric manufactured by Yuho Co., Ltd. (material: polyethylene terephthalate, manufacturing method: spunlace method, weight per unit area: 120 g/m ² ) is folded in two along the direction of flow (longitudinal direction), and the tip of the rod is applied to the crease. A swab 1 was produced by sandwiching a rod between one surface and the other surface and then attaching a cotton ball portion by ultrasonically welding and fusing.

(Production Example 3: Production of swab 2)
A swab 2 was produced in the same manner as in Production Example 2, except that a nonwoven fabric manufactured by Shinwa Co., Ltd. (material: polyethylene terephthalate, manufacturing method: spunlace method, basis weight: 100 g/m ² ) was used as the nonwoven fabric.

(Evaluation 1: Measurement of tensile strength)
After threading the cotton balls of swabs 1 and 2, the thread passed through the cotton balls of swab 1 was fixed to the grip of Instron 5582 (universal material testing machine), and the handle of swab 1 was fixed. Then, the cotton ball was pulled in the direction of elongation of the swab at a pulling speed of 100 mm/min, and the maximum load was measured. As a result, the tensile strength of swab 1 was 17.3N, and the tensile strength of swab 2 was 13.7N. The test atmosphere had a temperature of 23±2° C. and a relative humidity of 50±10%.

As described above, it is understood that the swab 1 using a nonwoven fabric with a basis weight of 120 g/m ² and the swab 2 using a nonwoven fabric with a basis weight of 100 g/m ² both have high tensile strength. can.

(Evaluation 2: sample collection amount)
Zelina (trade name, manufactured by Well Harmony) was dissolved in water to a concentration of 0.5% by weight to prepare a 0.5% by weight aqueous Zelina solution (gel solution). Also, gelatin was dissolved in water to a concentration of 1.0% by weight to prepare a 1.0% by weight gelatin aqueous solution.

Swab 1, a floc swab manufactured by Copan, and a sponge swab manufactured by Nipro were immersed in distilled water, 0.5% by weight aqueous Zelina solution, and 1.0% by weight aqueous Zelina solution for 10 seconds, respectively, and then pulled up to increase the weight. Minutes (mg) were measured. The results are set forth in Table 1 below. The weight increase relative to distilled water is the "amount of water collected", the weight increase relative to the 0.5% by weight aqueous solution of Zelina is the "amount of 0.5% by weight Zelina collected", and the weight increase relative to the 1.0% by weight aqueous solution of Zelina is This is referred to as "1.0% by weight of gelatin collected".

The swab 2 was immersed in distilled water for 10 seconds and then pulled up to measure the weight increase (mg). The results are listed in Table 2. The amount of weight increase with respect to distilled water is referred to as "amount of collected water". Table 2 also shows the results of swab 1 for comparison.

Swabs 1 and 2 were immersed in water in which food blue was dissolved (food blue solution) for 10 seconds, then withdrawn, the absorbance of the cotton bulb of swab 1 was measured, and the release rate was determined by dividing by the absorbance of the food blue solution. (%) was calculated. The results are set forth in Table 2 below. In addition, it is obtained by calculating as below the release rate (%). Release rate (%) = [(absorbance of swab cotton ball)/(absorbance of edible green solution)] x 100

As described above, swab 1 showed high values for the amount of collected water and gel-like solution and the release rate of water. On the other hand, the flock swabs manufactured by Copan and the sponge swabs manufactured by Nipro showed low values in terms of the amount of water and gel-like solution collected. Additionally, swab 2 nominated a significantly lower release rate. The reason for the large difference in release rate between swab 1 and swab 2 is not clear, but it is presumed to be due to the manufacturing method of the nonwoven fabric used and the difference in basis weight. That is, the swab 1 has a basis weight of 120 g/m ² and uses a nonwoven fabric formed by the spunlace method, so it is considered that the water collection amount and release rate (release efficiency) are high. be done.

(Evaluation 3)
Zelina (trade name, manufactured by Well Harmony) was dissolved in water to a concentration of 1.5% by weight to prepare a 1.5% by weight aqueous Zelina solution (gel solution). Also, gelatin was dissolved in water to a concentration of 3.0% by weight to prepare a 3.0% by weight gelatin aqueous solution.

The swab 1 was fixed to an Instron 5582 load cell using swab-fixing silicon, and the position where the tip of the cotton ball of the swab touched the surface of the 1.5% by weight gelatin aqueous solution placed in the beaker was the measurement start point. Then, the load and displacement were measured when the load cell was continuously lowered. The load cell maximum load is 100 N, and the crosshead speed is 500 mm/min. A specific method will be described with reference to FIG. 3, 21 is a load cell, 22 is silicon for fixing a swab (swab fixing silicon), 23 is a swab 1, 24 is a fibrous body, and 25 is a beaker containing a 1.5% by weight gelatin aqueous solution.

When the measurement was started, the load increased as the displacement increased until the tip of the cotton ball portion of the swab was inserted into the surface of the aqueous gelatin solution. Then, when the displacement exceeded a certain level, the tip of the cotton ball portion of the swab was inserted into the surface of the gelatin aqueous solution, and the load dropped sharply. The displacement and load at this time are referred to as "load (N) when inserting swab" and "displacement (mm) when inserting swab".

In addition, the load and displacement when using a 3% by weight aqueous solution of Zelina instead of an aqueous solution of 1.5% by weight of Zelina, and using a flock swab manufactured by Copan and a sponge swab manufactured by Nipro in place of swab 1. was measured. Table 3 shows the above measurement results.

Compared to the floc swab and the sponge swab, the swab 1 has a lower "load (N) when the swab is inserted" and a smaller "displacement (mm) when the swab is inserted". From this, it can be understood that the swab of the present invention can easily collect highly viscous specimens. Therefore, by using the swab of the present invention, it is possible to collect specimens from the nasal cavity and the oral cavity without making the subject feel pain.

Reference numerals 1: handle 2: rod 3: distal end 4: sample collecting portion 11: distal end 12: retainer tip Returning piece portion 13... Retaining tip 14... Flange part 15... Fiber body 16... Fiber body bag opening 21... Load cell 22... Swab Silicon for fixation (silicon for swab fixation)
23 ... swab 1
24...Fibrous body 25...Beaker containing 1.5% by weight gelatin aqueous solution

Claims (6)

a rod having a distal end region having a distal end portion, a flange portion, and a barb portion positioned therebetween and having a retaining tip;
A sample collection swab comprising: a bag-like fibrous body wrapped around the tip region of the rod ,
A specimen collection swab in which the distance from the central axis of the rod to the retaining tip is longer than the distance from the central axis of the rod to the extended end of the flange. A specimen collection swab comprising a rod and a bag-like fibrous body (excluding taslan-treated cloth) wrapped around a tip region of the rod,
The bag-shaped fibrous body is formed of a nonwoven fabric,
A specimen collection swab in which the nonwoven fabric has a basis weight of 110 to 130 g/m ² . 3. The specimen collection swab of Claim 2, wherein the nonwoven is a spunlaced nonwoven. The specimen collection swab according to any one of claims 1 to 3, wherein the fibrous body is wrapped around the rod without being fixed with an adhesive. The specimen collection swab according to any one of claims 1 to 4, wherein the fibrous body is made of polyethylene terephthalate. The specimen collection swab according to any one of Claims 1 to 5, which is for biological specimen collection.

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