JP7078350B2 - Dna抗体構築物及びその使用方法 - Google Patents
Dna抗体構築物及びその使用方法 Download PDFInfo
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- JP7078350B2 JP7078350B2 JP2016538531A JP2016538531A JP7078350B2 JP 7078350 B2 JP7078350 B2 JP 7078350B2 JP 2016538531 A JP2016538531 A JP 2016538531A JP 2016538531 A JP2016538531 A JP 2016538531A JP 7078350 B2 JP7078350 B2 JP 7078350B2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
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- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
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- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/522—CH1 domain
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- C—CHEMISTRY; METALLURGY
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
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- C07K2317/55—Fab or Fab'
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
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- C12N2770/24171—Demonstrated in vivo effect
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- C12N2770/00011—Details
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- C12N2770/00011—Details
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
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JP2021108614A JP2021166534A (ja) | 2013-12-13 | 2021-06-30 | Dna抗体構築物及びその使用方法 |
JP2023108341A JP2023138998A (ja) | 2012-12-13 | 2023-06-30 | Dna抗体構築物及びその使用方法 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
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US201361896646P | 2013-10-28 | 2013-10-28 | |
USPCT/US2013/075137 | 2013-12-13 | ||
PCT/US2013/075137 WO2014093894A2 (en) | 2012-12-13 | 2013-12-13 | Dna antibody constructs and method of using same |
PCT/US2014/070188 WO2015089492A2 (en) | 2013-12-13 | 2014-12-13 | Dna antibody constructs and method of using same |
Related Child Applications (2)
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JP2020035240A Division JP2020108381A (ja) | 2012-12-13 | 2020-03-02 | Dna抗体構築物及びその使用方法 |
JP2021108614A Division JP2021166534A (ja) | 2012-12-13 | 2021-06-30 | Dna抗体構築物及びその使用方法 |
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JP2017500030A JP2017500030A (ja) | 2017-01-05 |
JP2017500030A5 JP2017500030A5 (enrdf_load_stackoverflow) | 2018-01-25 |
JP7078350B2 true JP7078350B2 (ja) | 2022-05-31 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2020108381A (ja) * | 2012-12-13 | 2020-07-16 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | Dna抗体構築物及びその使用方法 |
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GB201704417D0 (en) * | 2017-03-20 | 2017-05-03 | Univ Copenhagen | Improved li vaccine adjuvant |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2006526409A (ja) | 2003-06-03 | 2006-11-24 | セル ジェネシス インコーポレイテッド | ペプチド開裂部位を用いた単一ベクターからの組換えポリペプチドの高められた発現のための構成と方法 |
JP2012504955A (ja) | 2008-10-13 | 2012-03-01 | インスティテュート・フォー・リサーチ・イン・バイオメディシン | デングウイルス中和抗体およびその使用 |
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US7714119B2 (en) * | 2004-07-13 | 2010-05-11 | Biosante Pharmaceuticals, Inc. | AAV vector compositions and methods for enhanced expression of immunoglobulins using the same |
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- 2014-12-13 JP JP2016538531A patent/JP7078350B2/ja active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006526409A (ja) | 2003-06-03 | 2006-11-24 | セル ジェネシス インコーポレイテッド | ペプチド開裂部位を用いた単一ベクターからの組換えポリペプチドの高められた発現のための構成と方法 |
JP2012504955A (ja) | 2008-10-13 | 2012-03-01 | インスティテュート・フォー・リサーチ・イン・バイオメディシン | デングウイルス中和抗体およびその使用 |
Non-Patent Citations (3)
Title |
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Jianmin Fang et al.、Nature Biotechnology、英国、2005.04.17発行、Vol. 23, No. 5、p. 584-590 |
Jin Hee Kim et al.、PLoS ONE、米国、2011.04.発行、Vol. 6, Issue 4, e18556、p. 1-8 |
Pablo de Felipe et al、TRENDS in Biotechnology、米国、2006.02.発行、Vol. 24, No. 2、p. 68-75 |
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