JP6983962B1 - Alkaline cosmetics - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a cosmetic having a good usability in which an active ingredient is added to an alkaline cosmetic and having no restrictions such as a container design. SOLUTION: This is an alkaline lotion containing a salt-type chemical, and when the coefficient of friction is measured with an instrument, a lotion showing an effect was obtained. In addition, by blending a specific chelating agent with an alkaline cosmetic that easily discolors, a transparent and highly photostable state was obtained. [Selection diagram] Fig. 1

Description

The present invention relates to an alkaline cosmetic, and more particularly to the provision of a transparent alkaline cosmetic that reproduces the smooth feeling of the skin after bathing in an alkaline hot spring by making it alkaline and can be expected to have the effect by blending a drug.

In Japan, there is a culture of soaking in hot springs for a long time, and it is also known that hot spring water may have a specific effect depending on its quality. For this reason, cosmetics using alkaline hot spring water (Patent Document 1), which gives a smooth feeling of use, are used. Alkaline cosmetics have also been used for the purpose of removing unnecessary keratin (Patent Document 2).

Japanese Unexamined Patent Publication No. 2013-155171 Japanese Unexamined Patent Publication No. 2004-161641

However, since it is alkaline, when the cosmetic containing a salt-type drug is exposed to light, discoloration occurs, and there is a limitation that the container must have a light-shielding property. It has been desired to develop a cosmetic that is comfortable to use by adding an active ingredient to an alkaline cosmetic and that has no restrictions such as container design.

As a result of diligent research to solve the above-mentioned problems, the present inventors have obtained an alkaline toner containing a salt-type chemical, which is effective when the coefficient of friction is measured with an instrument. Furthermore, they have found that a transparent and highly photostable state can be obtained by adding a specific chelating agent to an alkaline lotion that easily discolors, and have completed the present invention.

That is, the alkaline cosmetic according to the present invention is characterized by containing an acid-type or salt-type drug and having a pH of 9.0 or more.
Further, the alkaline cosmetic according to the present invention does not contain oil or contains 1% by mass or less, and contains 0.03% by mass or more of a chelating agent. Further, the thickener can be contained in an amount of 0 to 2% by mass.
The agent to be blended in the cosmetic water according to the present invention is one or more selected from 4-methoxysalicylic acid potassium salt, 1-piperidin propionic acid, tranexamic acid, carcinone, and L-ascorbic acid 2-glucoside. It is a drug.

According to the present invention, by obtaining an alkaline cosmetic having a pH of 9.0 or more, a smooth feel derived from the alkalinity can be obtained after application, and the feeling of use is also good. Further, by blending a specific chelating agent, it is possible to provide a transparent cosmetic that does not discolor and has excellent long-term photostability. Furthermore, the effect can be expected by appropriately removing unnecessary keratin and allowing the acid-type or salt-type drug to penetrate more.

It is a figure which showed the friction before and after applying a lotion.

Hereinafter, the best embodiment of the present invention will be described.
The alkaline cosmetics according to the present invention include (a) acid-type or salt-type agents, (c) chelating agents, and (e).
The aqueous phase is an essential component.
Further, the pH of the alkaline cosmetic according to the present invention is 9.0 or more.

The alkaline cosmetic according to the present invention is water-based, and the properties thereof are not particularly limited, and examples thereof include a lotion, a beauty essence, and a mask.

[(A) Acid-type or salt-type drug]
The alkaline cosmetic according to the present invention contains an acid-type or salt-type drug as an active ingredient. Examples of the acid-type or salt-type drug include 4-methoxysalicylic acid potassium salt, 1-piperidin propionic acid, tranexamic acid, carnosine, L-ascorbic acid 2-glucoside, citric acid and the like. Includes 2 or more types.
4-Methoxysalicylic acid potassium salt is added to cosmetics as a whitening ingredient. 1-Piperidine propionic acid has the effect of suppressing skin aging. Tranexamic acid has a whitening effect. Carnosine has antioxidant properties. L-ascorbic acid 2-glucoside has a whitening effect. Citric acid has a beautiful skin effect.

The blending amount of the acid-type or salt-type drug in the present invention is 0.001 to 10.0% by mass. More preferably, it is 0.1 to 3.0% by mass. This is because if it is 0.001% by mass or less, the effect of the drug may not be sufficiently exhibited, and if it exceeds 10.0% by mass, the effect of the drug does not change.

[(B) Oil content]
The alkaline cosmetic according to the present invention does not have to contain oil. Further, when the oil content is contained for the purpose of blending a fragrance, a masking agent, an oily active ingredient, etc., it is preferably 1% by mass or less. This is because if it exceeds 1% by mass, the appearance is poor in a low temperature environment.

Examples of the oil content in the present invention include liquid fats and oils, solid fats and oils, waxes, hydrocarbons, higher fatty acids, higher alcohols, synthetic ester oils, silicone oils and the like.

[(C) Chelating agent]
In the alkaline cosmetics according to the present invention, the chelating agent is effective for maintaining the photostability of the alkaline cosmetics.
The blending amount of the chelating agent in the present invention is preferably 0.03 to 0.5% by mass, more preferably 0.05 to 0.1% by mass. If the blending amount of the chelating agent is 0.03% by mass or less, the effect may not be exhibited, and if it exceeds 0.5% by mass, it tends to precipitate in a low temperature environment, or cause discoloration or offensive odor. be.

Examples of the chelating agent included in the present invention include 1-hydroxyethane, 1-diphosphonic acid, 1-hydroxyethane-1,1-diphosphonic acid tetrasodium salt, disodium edetate, trisodium edetate, tetrasodium edetate, and citrate. Examples thereof include sodium acid, sodium polyphosphate, sodium metaphosphate, gluconic acid, phosphoric acid, succinic acid, ethylenediamine tetraacetic acid, ethylenediamine hydroxyethyl triacetate 3 sodium, and sodium hexametaphosphate.
Of these, ethylenediaminetetraacetic acid is preferable.

[(D) Thickener]
In the alkaline cosmetics according to the present invention, it is not necessary to add a thickener. Further, a thickener may be added for the purpose of imparting viscosity and improving usability. When a thickener is blended, it is preferably 2% by mass or less. More preferably, it is 0.2% by mass or less. This is because if it exceeds 2% by mass, it may cause a strange odor and deterioration of stickiness and skin familiarity.

Examples of the thickener in the present invention include Arabic gum, carrageenan, carrageenan, color yam gum, tragacanto gum, carob gum, quince seed (malmero), casein, dextrin, gelatin, sodium pectinate, sodium aragnate, methyl cellulose, ethyl cellulose, CMC, hydroxyethyl cellulose. , Hydroxypropyl Cellulose, PVA, PVM, PVP, Sodium Polyacrylate, Carrageenan Polymer, Locust Bean Gum, Gua Gum, Tamarinto Gum, Dialkyldimethylammonium Sulfate Cellulose, Xanthan Gum, Aluminum Magnesium Phosphate, Bentnite, Hectrite, A1Mg Syrate ( Bee gum), laponite, silicic anhydride and the like.
Of these, carboxyvinyl polymers are particularly preferable.

[(E) Aqueous phase]
The aqueous phase may contain components that are usually used as aqueous phase components in cosmetics, quasi-drugs, etc., and examples thereof include water and water-soluble alcohols. Further, a moisturizer, a water-soluble ultraviolet absorber, a powder, an organic amine, vitamins, a preservative, an antioxidant, a pH adjuster and the like can be appropriately blended.
Further, since the pH of this cosmetic is 9.0 or more, it is preferable to add an alkaline substance.

The water is not particularly limited, and examples thereof include purified water, ion-exchanged water, tap water, and the like.

Examples of the alkaline substance include sodium hydroxide, potassium hydroxide, sodium carbonate, potassium carbonate, sodium lactate, sodium citrate, sodium succinate, disodium monohydrogen phosphate and the like. These substances are alkaline and at the same time have an exfoliating effect. Particularly preferred are sodium hydroxide, potassium hydroxide and sodium carbonate.

Examples of the water-soluble alcohol include lower alcohols, polyhydric alcohols, polyhydric alcohol polymers, divalent alcohol alkyl ethers, dihydric alcohol ether esters, glycerin monoalkyl ethers, sugar alcohols, monosaccharides, oligosaccharides, and polysaccharides. And their derivatives.

Examples of the lower alcohol include ethanol, propanol, isopropanol, isobutyl alcohol, t-butyl alcohol and the like.

Examples of the polyhydric alcohol include divalent alcohols (eg, dipropylene glycol, 1,3-butylene glycol, ethylene glycol, trimethylene glycol, 1,2-butylene glycol, tetramethylene glycol, 2,3-butylene glycol, penta). Methylene glycol, 2-butene-1,4-diol, hexylene glycol, Okuchiren glycol, etc.) Trivalent alcohols (eg, glycerin, trimethylolpropane, etc.), tetravalent alcohols (eg, diglycerin, 1, 2, 2, Pentaerythritol such as 6-hexanetriol), pentavalent alcohol (eg, xylitol, triglycene, etc.), hexavalent alcohol (eg, sorbitol, mannitol, etc.), polyhydric alcohol polymer (eg, diethylene glycol, polypropylene glycol, tetraethylene glycol, etc.) , Diglycerin-triglycene, tetraglycerin, polyglycerin, etc.), divalent alcohol alkyl ethers (eg, ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, ethylene glycol monophenyl ether, ethylene glycol monohexyl) Ethers, ethylene glycol mono2-methylhexyl ethers, ethylene glycol isoamyl ethers, ethylene glycol benzyl ethers, ethylene glycol isopropyl ethers, ethylene glycol dimethyl ethers, ethylene glycol diethyl ethers, ethylene glycol dibutyl ethers, etc.), dihydric alcohol alkyl ethers (eg) , Diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol monobutyl ether, diethylene glycol dimethyl ether, diethylene glycol diethyl ether, diethylene glycol butyl ether, diethylene glycol methyl ethyl ether, triethylene glycol monomethyl ether, triethylene glycol monoethyl ether, propylene glycol monomethyl ether, propylene glycol mono Ethyl ether, propylene glycol monobutyl ether, propylene glycol isopropyl ether, dipropylene glycol methyl ether, dipropylene glycol ethyl ether, dipropylene glycol butyl ether, etc.), dihydric alcohol ether ester ( For example, ethylene glycol monomethyl ether acetate, ethylene glycol monoethyl ether acetate, ethylene glycol monobutyl ether acetate, ethylene glycol monophenyl ether acetate, ethylene glycol diazibate, ethylene glycol disuccinate, diethylene glycol monoethyl ether acetate, diethylene glycol monobutyl ether acetate. , Propropylene glycol monomethyl ether acetate, propylene glycol monoethyl ether acetate, propylene glycol monopropyl ether acetate, propylene glycol monophenyl ether acetate, etc.), glycerin monoalkyl ether (eg, xyl alcohol, ceracyl alcohol, batyl alcohol, etc.), sugar Alcohols (eg, maltotriose, mannitol, sucrose, erythritol, glucose, fructose, starch-degrading sugar, maltose, starch-degrading sugar-reduced alcohol, etc.), glycerides, tetrahydrofurfuryl alcohols, POE-tetrahydrofurfuryl alcohols, Examples thereof include POP-butyl ether, POP / POE-butyl ether tripolyoxypropylene glycol ether, POP-glycerin ether, POP-glycerin ether phosphoric acid, POP / POE-pentaerythritol ether, polyglycerin and the like.

Examples of the monosaccharide include tricarbose (eg, D-glycerylaldehyde, dihydroxyacetone, etc.), tetracarbose (eg, D-erythrose, D-erythrose, D-treose, erythritol, etc.), and pentacarbonate (eg, erythritol). , L-arabinose, D-xylose, L-lyxose, D-arabinose, D-ribose, D-librose, D-xylrose, L-xylrose, etc.), Hexosaccharide (eg, D-glucose, D-talose, D) -Bushicose, D-galactose, D-fluctose, L-galactose, L-mannose, D-tagatose, etc.), seven-carbon sugar (eg, aldoheptose, heprose, etc.), eight-carbon sugar (eg, octulose, etc.), deoxy sugar (eg, octulose, etc.) For example, 2-deoxy-D-ribose, 6-deoxy-L-galactose, 6-deoxy-L-mannose, etc., amino sugars (eg, D-glucosamine, D-galactosamine, sialic acid, aminouronic acid, muramic acid, etc.) ), Uronic acid (for example, D-glucuronic acid, D-mannuronic acid, L-gluuronic acid, D-galacturonic acid, L-isulonic acid, etc.) and the like.

Examples of oligosaccharides include sucrose, gunthianose, umbelliferose, lactose, planteose, isolycnoses, α, α-trehalose, raffinose, lycnoses, umbilicin, stachyose velvas and the like.

Examples of the polysaccharide include cellulose, quince seed, starch, galactan, dermatan sulfate, glycogen, arabic gum, heparan sulfate-tragant gum, keratan sulfate, chondroitin, xanthan gum, guagam, dextran, kerato sulfate, locust bean gum, succinoglucan and the like. Can be mentioned.

Examples of other polyols include polyoxyethylene methylglucoside (Glucam E-10) and polyoxypropylene methylglucoside (Glucam P-10).

Natural water-soluble polymers include, for example, plant-based polymers (eg, Arabic gum, tragacanto gum, galactan, guar gum, carob gum, color yam gum, carrageenan, pectin, canten, quince seed (malmero), algae colloid (cassow extract), starch. (Rice, corn, potato, wheat), glycyrrhizinic acid), microbial macromolecules (eg, xanthan gum, dextran, succinoglucan, purulan, etc.), animal macromolecules (eg, collagen, casein, albumin, gelatin, etc.), etc. Can be mentioned.

Examples of the semi-synthetic water-soluble polymer include a starch-based polymer (for example, carboxymethyl starch, methyl hydroxypropyl starch, etc.) and a cellulose-based polymer (methyl cellulose, ethyl cellulose, methyl hydroxypropyl cellulose, hydroxyethyl cellulose, cellulose sulfate, etc.). , Hydroxypropyl cellulose, carboxymethyl cellulose, sodium carboxymethyl cellulose, crystalline cellulose, cellulose powder, etc.), alginic acid-based polymers (for example, sodium alginate, propylene glycol alginate, etc.) and the like.

Examples of the synthetic water-soluble polymer include vinyl-based polymers (for example, polyvinyl alcohol, polyvinyl methyl ether, polyvinylpyrrolidone, carboxyvinyl polymer, etc.) and polyoxyethylene-based polymers (for example, polyethylene glycol 20,000, 40). , 000, 60,000, etc.), acrylic polymers (eg, sodium polyacrylate, polyethyl acrylate, polyacrylamide, etc.), polyethyleneimine, cationic polymers, and the like.

Moisturizing agents include, for example, chondroitin sulfate, hyaluronic acid, mucoitin sulfate, caronic acid, atelocolagen, cholesteryl-12-hydroxystearate, sodium lactate, bile acid salt, DL-pyrrolidone carboxylate, short chain soluble collagen, etc. Examples thereof include diglycerin (EO) PO adduct, Izayoi rose extract, Hyaluronic acid extract, Merilot extract and the like.

Examples of the water-soluble ultraviolet absorber include 2,4-dihydroxybenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone, 2,2'-dihydroxy-4,4'-dimethoxybenzophenone, 2,2', 4, 4'-Tetrahydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonate, 4-phenylbenzophenone, Benzophenone-based ultraviolet absorbers such as 2-ethylhexyl-4'-phenyl-benzophenone-2-carboxylate, 2-hydroxy-4-n-octoxybenzophenone, 4-hydroxy-3-carboxybenzophenone, phenylbenzimidazole-5- Sulfonic acid and its salts, benzoimidazole-based ultraviolet absorbers such as phenylene-bis-benzoimidazole-tetrasulfonic acid and its salts, 3- (4'-methylbenzylidene) -d, l-phenyl, 3-benziliden-d, Examples thereof include l-phenyl, urocanic acid, urocanic acid ethyl ester and the like.

Examples of the powder component include inorganic powders (eg, talc, kaolin, mica, silk mica (serisite), white mica, gold mica, synthetic mica, red mica, black mica, permiculite, magnesium carbonate, calcium carbonate, silicic acid. Aluminum, barium silicate, calcium silicate, magnesium silicate, strontium silicate, metal tungstate, magnesium, silica, zeolite, barium sulfate, calcined calcium sulfate (baked sekko), calcium phosphate, fluoroapatite, hydroxyapatite, ceramic powder , Metal soap (eg zinc myristate, calcium palmitate, aluminum stearate), boron nitride, etc.), organic powder (eg polyamide resin powder (nylon powder), polyethylene powder, polymethyl methacrylate powder, polystyrene powder, styrene And acrylic acid copolymer resin powder, benzoguanamine resin powder, polytetrafluorinated ethylene powder, cellulose powder, etc.), inorganic white pigments (eg, titanium dioxide, zinc oxide, etc.), inorganic red pigments (eg, iron oxide (eg, iron oxide) Bengala), iron titanate, etc.), inorganic brown pigments (eg, γ-iron oxide, etc.), inorganic yellow pigments (eg, yellow iron oxide, yellow clay, etc.), inorganic black pigments (eg, black iron oxide, low). Secondary titanium oxide, etc.), Inorganic purple pigments (eg, mango violet, cobalt violet, etc.), Inorganic green pigments (eg, chromium oxide, chromium hydroxide, cobalt titanate, etc.), Inorganic blue pigments (eg, ultramarine, etc.) Navy blue, etc.), pearl pigments (eg, titanium oxide coated mica, titanium oxide coated bismuth oxychloride, titanium oxide coated talc, colored titanium oxide coated mica, bismuth oxychloride, fish scale foil, etc.), metal powder pigments (eg, aluminum powder) , Copper powder, etc.), organic pigments such as zirconium, barium or aluminum lake (eg, Red 201, Red 202, Red 204, Red 205, Red 220, Red 226, Red 228, Red Organic pigments such as 405, orange 203, orange 204, yellow 205, yellow 401, and blue 404, red 3, red 104, red 106, red 227, red 230, red 401. No., Red No. 505, Orange No. 205, Yellow No. 4, Yellow No. 5, Yellow No. 202, Yellow No. 203, Green No. 3 and Blue No. 1, etc.), Natural pigments (eg, chlorophyll, β-carotene, etc.) Can be mentioned.

Examples of the organic amine include monoethanolamine, diethanolamine, triethanolamine, morpholine, tetrax (2-hydroxypropyl) ethylenediamine, triisopropanolamine, 2-amino-2-methyl-1,3-propanediol and 2-amino. -2-Methyl-1-propanol and the like can be mentioned.

Examples of vitamins include vitamins A, B1, B2, B6, C, E and their derivatives, pantothenic acid and its derivatives, biotin and the like.
Examples of the antioxidant include tocopherols, dibutylhydroxytoluene, butylhydroxyanisole, gallic acid esters and the like.
Examples of the antioxidant aid include phosphoric acid, citric acid, ascorbic acid, maleic acid, malonic acid, succinic acid, fumaric acid, kephalin, hexametaphosphate, phytic acid, ethylenediamine tetraacetic acid and the like.

Examples of the pH adjuster include buffers such as lactic acid-sodium lactate, citric acid-sodium citrate, and succinate-sodium succinate.

Further, in the present invention, PEG / PPG dimethyl ether that is soluble in water may be blended as an aqueous phase component. Examples of specific compounds include PEG1500, PEG / PPG-14 / 7 dimethyl ether, PEG / PPG-17 / 4 dimethyl ether and the like.

The proportion of the aqueous phase in the alkaline cosmetic according to the present invention is not particularly limited, but as a guide, it is 50 to 90% by mass, preferably 60 to 80% by mass.

Further, the alkaline cosmetic according to the present invention may contain a surfactant as an aqueous phase component within a range that does not impair the effects of the present invention. Examples of such surfactants include amphoteric surfactants, cationic surfactants, anionic surfactants, nonionic surfactants and the like.
The blending amount when the surfactant is contained is preferably 5.0% by mass or less. More preferably, it is 1.0% by mass or less.

The amphoteric tenside has at least one cationic and one anionic functional group, is cationic when the solution is acidic, is anionic when the solution is alkaline, and is close to a nonionic surfactant near the isoelectric point. It has properties.
Amphoteric surfactants are classified into carboxylic acid type, sulfate ester type, sulfonic acid type and phosphoric acid ester type according to the type of anionic group. Carboxylic acid type, sulfuric acid ester type and sulfonic acid type are preferable for the present invention. The carboxylic acid type is further classified into an amino acid type and a betaine type. Particularly preferably, it is a betaine type.
Specifically, for example, an imidazoline-based amphoteric surfactant (for example, 2-undecyl-N, N, N- (hydroxyethylcarboxymethyl) -2-imidazoline sodium, 2-cocoyl-2-imidazolinium hydroxide- 1-Carboxytyloxy 2-sodium salt, etc.); Betaine-based surfactants (eg, 2-heptadecyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine, lauryldimethylaminoacetic acid betaine, alkylbetaine, amide betaine, sulfo) Betaine, etc.) and the like.

Examples of the cationic surfactant include quaternary ammonium salts such as cetyltrimethylammonium chloride, stearyltrimethylammonium chloride, behenyltrimethylammonium chloride, behenyldimethylhydroxyethylammonium chloride, stearyldimethylbenzylammonium chloride, and cetiltriethylammonium methylsulfate. Can be mentioned. In addition, stearate diethylaminoethylamide, stearate dimethylaminoethylamide, palmitate diethylaminoethylamide, palmitate dimethylaminoethylamide, myristic acid diethylaminoethylamide, myristic acid dimethylaminoethylamide, behenic acid diethylaminoethylamide, behenate dimethyl. Aminoethylamide, diethylaminopropylamide stearate, dimethylaminopropylamide stearate, diethylaminopropylamide palmitate, dimethylaminopropylamide palmitate, diethylaminopropylamide myristic acid, dimethylaminopropylamide myristine, diethylaminopropylamide behenic acid, behenin Examples thereof include amide amine compounds such as acid dimethylaminopropylamide.

Examples of the anionic surfactant include a carboxylate type such as fatty acid soap, N-acylglutamate and alkyl ether acetic acid, a sulfonic acid type such as α-olefin sulfonate, alkane sulfonate and alkylbenzene sulfonic acid, and higher alcohols. It is classified into a sulfate ester salt type such as a sulfate ester salt, a phosphoric acid ester salt type, and the like. It is preferably a carboxylate type, a sulfonic acid type and a sulfate ester salt type, and particularly preferably a sulfate ester salt type.
Specifically, for example, fatty acid soap (for example, sodium laurate, sodium palmitate, etc.), higher alkyl sulfate ester salt (for example, sodium lauryl sulfate, potassium lauryl sulfate, etc.), alkyl ether sulfate ester salt (for example, POE-). Triethanolamine lauryl sulfate, POE-sodium lauryl sulfate, etc.), N-acylsarcosic acid (eg, sodium lauroyl sarcosin, etc.), higher fatty acid amide sulfonate (eg, N-myristoyl-N-methyltaurine sodium, coconut oil fatty acid, etc.) Methyl taurid sodium, lauryl methyl taurid sodium, etc.), phosphate ester salts (POE-oleyl ether phosphate sodium, POE-stearyl ether phosphate, etc.), sulfosuccinates (eg, di-2-ethylhexyl sulfosuccinate sodium, etc.) Monolauroyl monoethanolamide polyoxyethylene sulfosuccinate sodium, lauryl polypropylene glycol sulfosuccinate sodium, etc.), alkylbenzene sulfonates (eg, linear dodecylbenzene sulfonate sodium, linear dodecylbenzene sulfonate triethanolamine, lineardodecylbenzene sulfonic acid, etc.) ), Higher fatty acid ester sulfate ester salt (eg, hardened coconut oil fatty acid sodium glycerin sulfate, etc.), N-acylglutamate (eg, N-sodium lauroyl glutamate, disodium N-stearoyl glutamate, N-myristoyl-L-glutamic acid). Monosodium, etc.), sulfated oil (eg, funnel oil, etc.), POE-alkyl ether carboxylic acid, POE-alkylallyl ether carboxylate, α-olefin sulfonate, higher fatty acid ester sulfonate, secondary alcohol sulfate Examples thereof include ester salts, higher fatty acid alkyrrole amide sulfate ester salts, sodium lauroyl monoethanolamide succinate, ditriethanolamine N-palmitoyl aspartate, and sodium caseinate.

Other ingredients include, for example, preservatives (ethylparaben, butylparaben, chlorphenesin, phenoxyethanol, etc.); anti-inflammatory agents (eg, glycylic acid derivative, glycyrrhetinic acid derivative, salicylic acid derivative, hinokithiol, zinc oxide, allantin, etc.). Whitening agents (eg, placenta extract, yukinoshita extract, albutin, etc.); Various extracts (eg, sardines, olen, shikon, shakuyaku, assembly, birch, sage, biwa, carrot, aloe, zenia oi, iris, grapes, etc. Yokuinin, Hechima, Yuri, Saffron, Senkyu, Shokyo, Otogirisou, Ononis, Garlic, Togarashi, Chimpi, Toki, Seaweed, etc.; Activators (eg, royal jelly, photosensitizers, cholesterol derivatives, etc.); Blood circulation promoters (eg, Nonyl acid vanillyl amide, nicotinic acid benzyl ester, nicotinic acid β-butoxyethyl ester, capsaicin, zingeron, cantalistinki, ictamol, tannic acid, α-borneol, tocopherol nicotinate, inositol hexanicotinate, cyclandelate, cinnaridine , Trazoline, acetylcholine, verapamil, cepharanthin, γ-orizanol, etc.); antilipolytic agents (eg, sulfur, thiantoll, etc.); anti-inflammatory agents (eg, tranexamic acid, thiotaurine, hypotaurine, etc.) and the like.

The present invention will be described in more detail below with reference to specific examples, but the present invention is not limited to the following examples. The blending amount is mass% unless otherwise specified.

First, the inventors examined whether the friction between the alkaline toner according to the present invention and the toner in the neutral region was different.
[Friction measurement method]
Both cheeks of 15 men and women were applied and measured, and 30 minutes after washing the face, 2 mL of alkaline preparation A or neutral preparation B was applied to either the left or right cheek with cotton.
A friction meter (FR700, C + K) was used to measure the friction, and the measurement was performed 12 times after the probe was placed, and the average value of the 2nd to 8th times was calculated.
The composition of the lotion used for the measurement is shown in Table 1, and the results are shown in FIG.

For the effect of the drug on the skin, compare the difference or ratio obtained by subtracting the value before application from each measured value, and if there is normality, the paired-t test, if there is no normality, the Wilcoxon signed rank sum test. Therefore, a significant difference test was performed on both sides. The significance level was set to 5%.
In both cases, it was found that the neutral preparation B was significantly higher, and the alkaline preparation A had a smaller increase in friction (leading to a slippery and smooth state).

The inventors examined the amount of 4-methoxysalicylic acid potassium salt and the amount of thickener. The results are shown in Table 2.
The evaluation methods were as follows.

[Evaluation of turbidity]
[Method]
The turbidity of cosmetics was measured with a Poic integrating sphere turbidity meter (blackboard method). The lower the turbidity, the higher the transparency, and the higher the turbidity, the more turbid.
[Evaluation criteria]
A: Transparent B: Slight turbidity is observed, but acceptable.
C: Turbidity is observed.

[Evaluation of light stability]
[Method]
The test sample was placed in a transparent airtight glass container, exposed to sunlight (50 megajoules), visually observed, and evaluated according to the following evaluation criteria.
[Evaluation criteria]
A: No discoloration is observed.
B: Slight discoloration is observed, but it is acceptable.
C: Some discoloration is observed.
D: Clear discoloration is observed.

In addition, the evaluation criteria for "appearance immediately after" are the same, but the result is that they have not been exposed to sunlight.

From Table 2, Example 1 showed that photostability was obtained without the addition of the potassium 4-methoxysalicylic acid salt, but in Example 2, a slight discoloration was observed when 1% by mass of the potassium 4-methoxysalicylic acid salt was contained. .. Further, when 3% by mass of the potassium 4-methoxysalicylic acid salt was contained in Example 3, a slight discoloration was observed immediately after the preparation, and the stability was not good. However, even when 3% by mass of 4-methoxysalicylic acid potassium salt was added as in Example 4, no discoloration was observed immediately after the addition of sodium alginate, which is a thickener.
It is considered that the greater the amount of both the 4-methoxysalicylic acid potassium salt and the thickener, the more likely it is that discoloration will occur.

Next, the inventors examined whether or not the photostability changes depending on the amount and type of (c) chelating agent when 3% by mass of 4-methoxysalicylic acid potassium salt is added. The results are shown in Table 3.

From Table 3 Example 5-6, (a) even when 3% by mass of 4-methoxysalicylic acid potassium salt is contained, (c) immediately after adding disodium edetate or trisodium edetate as a chelating agent. It was shown that the appearance and light stability of the were good. However, there were some chelating agents such as Example 8 in which no effect was obtained.

Furthermore, the inventors examined whether the photostability was changed depending on the drug to be blended. The results are shown in Table 4.

From Table 4, it was shown that a certain level of photostability can be obtained regardless of which drug is blended. In addition, the photostability was good not only with one type but also with a plurality of combinations.

[Prescription example 1: Toner]
Ingredient content (mass%)
Water Residual Ethyl Alcohol 3.0
Glycerin 3.0
Dipropylene glycol 6.0
Polyethylene glycol 1540, polyethylene glycol 300
11.0
Polyoxyethylene (14) Polyoxypropylene (7) Dimethyl ether
1.0
Polyoxyethylene polyoxypropylene decyltetradecyl ether (24EO) (13PO) 0.3
4-Methoxysalicylic acid potassium salt 3.0
Disodium edetate 0.1
Panax ginseng extract 0.1
Sodium hydrogen carbonate Appropriate amount Sodium hydroxide Appropriate amount Phenoxyethanol Appropriate amount Formulated fragrance Appropriate amount

[Prescription example 2: Toner]
Ingredient content (mass%)
Water Residual Ethyl Alcohol 3.0
Glycerin 3.0
Dipropylene glycol 6.0
Polyethylene glycol 1540, polyethylene glycol 300
11.0
Polyoxyethylene (14) Polyoxypropylene (7) Dimethyl ether
1.0
Polyoxyethylene polyoxypropylene decyltetradecyl ether (24EO) (13PO) 0.3
4-Methoxysalicylic acid potassium salt 3.0
Disodium edetate 0.1
Mishima Psycho Root Extract 0.1
Sodium hydrogen carbonate Appropriate amount Sodium hydroxide Appropriate amount Phenoxyethanol Appropriate amount Formulated fragrance Appropriate amount

Claims (3)

(A) One or more acid-type or salt-type active ingredients (drugs) selected from the group consisting of potassium 4-methoxysalicylic acid, tranexamic acid, and carnosine, and
(C) The chelating agent contains one or more selected from the group consisting of disodium edetate, trisodium edetate, and pentaethylenetriaminepentaacetic acid in an amount of 0.05 to 0.1% by mass.
A cosmetic characterized by having a pH of 9.0 or higher. The cosmetic according to claim 1, wherein (b) oil is not contained, or even if it is contained, it is 1% by mass or less. The cosmetic according to claim 1 or 2, wherein the amount of the thickener (d) is 0 to 2% by mass.

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