JP6961534B2

JP6961534B2 - Filter jig and sampling method

Info

Publication number: JP6961534B2
Application number: JP2018107090A
Authority: JP
Inventors: 規宮城島; 竜太竹上
Original assignee: Fujifilm Corp
Current assignee: Fujifilm Corp
Priority date: 2018-06-04
Filing date: 2018-06-04
Publication date: 2021-11-05
Anticipated expiration: 2038-06-04
Also published as: JP2019208427A

Description

本発明は、濾過によって細胞および粒子等を回収するフィルター治具、および、このフィルター治具を用いるサンプリング方法に関する。 The present invention relates to a filter jig for collecting cells, particles, etc. by filtration, and a sampling method using the filter jig.

各種の病気における検査、医療等の研究における細胞の分離および細胞の篩分け、被処理液からの夾雑物の除去、ならびに、粒子を分散する液体からの粒子の回収等に、濾過によって目的を回収するフィルター治具が利用されている。 The purpose is recovered by filtration for examination in various diseases, cell separation and cell sieving in medical research, removal of impurities from the liquid to be treated, and recovery of particles from the liquid that disperses particles. Filter jigs are used.

例えば、単細胞（シングルセル）懸濁液の調製、単細胞の抽出、一定の大きさ細胞集団の抽出、および、細胞の凝集塊の除去等に、セルストレーナーと呼ばれるフィルター治具が用いられている。
一例として、特許文献１には、円筒状のチューブの開口部に保持されて、被処理液を濾過するセルストレーナーとして、上方が開口し被処理液を濾過する濾過部と、濾過部をチューブの開口に保持する保持部と、チューブに保持した際に、チューブの内部と外部とを連通する連通部とを有するセルストレーナーが記載されている。 For example, a filter jig called a cell strainer is used for preparing a single cell suspension, extracting a single cell, extracting a cell population of a certain size, and removing agglomerates of cells.
As an example, in Patent Document 1, as a cell strainer held in an opening of a cylindrical tube and filtering a liquid to be treated, a filtering portion having an upper opening for filtering the liquid to be treated and a filtering portion are used as a tube. Described is a cell strainer having a holding portion that is held in the opening and a communicating portion that communicates the inside and the outside of the tube when held in the tube.

特開２０１３−１４１４５６号公報Japanese Unexamined Patent Publication No. 2013-141456

特許文献１に記載されるセルストレーナーは、重力落下によって被処理液の濾過を行う。そのため、濾過のための減圧等による圧力によって、残渣および濾液に含まれる細胞等が損傷することを防止できる。
また、セルストレーナーを装着するチューブの内部と外部とを連通する連通部を有するために、この連通部が、いわゆるエア抜き（空気抜き）となって、重力落下でも、円滑な濾過を行うことが可能である。 The cell strainer described in Patent Document 1 filters the liquid to be treated by gravity drop. Therefore, it is possible to prevent the residue and the cells contained in the filtrate from being damaged by the pressure due to the reduced pressure for filtration or the like.
In addition, since it has a communication part that communicates the inside and outside of the tube to which the cell strainer is mounted, this communication part becomes so-called air bleeding (air bleeding), and smooth filtration can be performed even if gravity drops. Is.

このような特許文献１に記載されるセルストレーナーによれば、濾液中に目的物が存在する場合には、迅速かつ目的物を損傷することなく、濾過を行うことができる。
しかしながら、このセルストレーナーでは、目的物が残渣中に存在する場合には、スパチュラ等を用いてフィルター（濾過部）から残渣を取り出す必要があるため、手間がかかり、また、フィルターに残渣が残り易く回収率も低くなる。さらに、スパチュラ等を用いてフィルターから残渣等を取り出す際に、目的物を損傷してしまう可能性もある。 According to the cell strainer described in Patent Document 1, when the target product is present in the filtrate, filtration can be performed quickly and without damaging the target product.
However, in this cell strainer, when the target substance is present in the residue, it is necessary to take out the residue from the filter (filtration unit) using a spatula or the like, which is troublesome and tends to leave the residue on the filter. The recovery rate is also low. Further, when the residue or the like is taken out from the filter using a spatula or the like, the target object may be damaged.

また、スパチュラ等を用いずに、フィルターから残渣を回収する方法として、フィルターを洗浄液等に浸す方法もあるが、洗浄液中の目的物濃度が低くなりやすく、回収率が低くなってしまう可能性が高い。 Further, as a method of recovering the residue from the filter without using a spatula or the like, there is also a method of immersing the filter in a cleaning liquid or the like, but the concentration of the target substance in the cleaning liquid tends to be low, and the recovery rate may be low. high.

本発明の目的は、このような従来技術の問題点を解決することにあり、残渣中に目的物が存在する濾過を行う際に、濾過を円滑かつ迅速に行えると共に、目的物を高い回収率で容易に回収でき、しかも、目的物の損傷も防止できるフィルター治具、および、このフィルター治具を用いるサンプリング方法を提供することにある。 An object of the present invention is to solve such a problem of the prior art, and when performing filtration in which the target product is present in the residue, the filtration can be performed smoothly and quickly, and the target product can be recovered at a high recovery rate. It is an object of the present invention to provide a filter jig that can be easily collected by the user and can prevent damage to an object, and a sampling method using the filter jig.

この課題を解決するために、本発明は、以下の構成を有する。
［１］貫通孔を有する治具本体と、
治具本体の貫通孔の途中に設けられるフィルターと、
治具本体の、フィルターよりも貫通孔の一方の端部側、および、フィルターよりも貫通孔の他方の端部側に設けられる、エア抜き機構と、を有することを特徴とするフィルター治具。
［２］治具本体の外壁の一部が、エア抜き機構の少なくとも１つを構成する、［１］に記載のフィルター治具。
［３］治具本体の外壁の一部が、全てのエア抜き機構を構成する、［２］に記載のフィルター治具。
［４］エア抜き機構を構成する治具本体の外壁の一部が、治具本体の外観形状の連続性を失わせるように、外壁面が貫通孔に近接する形状を有する、［２］または［３］に記載のフィルター治具。
［５］エア抜き機構を構成する治具本体の外壁の一部が、治具本体の一部を欠損した形状を有する、［４］に記載のフィルター治具。
［６］治具本体の貫通孔の少なくとも一方の端部側に、貫通孔を通過した液体を収容する収容容器と係合する係合部を有する、［１］〜［５］のいずれかに記載のフィルター治具。
［７］係合部が、収容容器の外側に係合する、［６］に記載のフィルター治具。
［８］係合部が、収容容器に係合する凹部を有する、［６］または［７］に記載のフィルター治具。
［９］係合部が、治具本体の貫通孔の外周方向に１以上の切り欠き部を有する、［６］〜［８］のいずれかに記載のフィルター治具。
［１０］係合部への収容容器の挿入位置と、エア抜き機構の位置とが、貫通孔の外周方向で一致している、［６］〜［９］のいずれかに記載のフィルター治具。
［１１］治具本体の貫通孔が、少なくとも一方の端部に対応して、フィルターから端部に向かう方向に拡径する拡径部を有する、［１］〜［１０］のいずれかに記載のフィルター治具。
［１２］治具本体の貫通孔の貫通方向から見た際に、フィルターよりも貫通孔の一方の端部側に設けられるエア抜き機構と、フィルターよりも貫通孔の他方の端部側に設けられるエア抜き機構とが、貫通孔を挟んで対向している、［１］〜［１１］のいずれかに記載のフィルター治具。
［１３］［１］〜［１２］のいずれかに記載のフィルター治具を用いるサンプリング方法であって、治具本体の貫通孔に、被処理液を通液した後、
被処理液の通液方向とは逆の方向に、治具本体の貫通孔に回収液を通液させることにより、フィルタ上の残渣を回収する、サンプリング方法。
［１４］治具本体の貫通孔の一方の端部を上に、他方の端部を下にして、落下によって、被処理液の通液、および、回収液の通液の、少なくとも一方を行う、［１３］に記載のサンプリング方法。 In order to solve this problem, the present invention has the following configuration.
[1] A jig body having a through hole and
A filter provided in the middle of the through hole of the jig body and
A filter jig characterized by having an air bleeding mechanism provided on one end side of the through hole with respect to the filter and on the other end side of the through hole with respect to the filter of the jig main body.
[2] The filter jig according to [1], wherein a part of the outer wall of the jig body constitutes at least one of the air bleeding mechanisms.
[3] The filter jig according to [2], wherein a part of the outer wall of the jig body constitutes all the air bleeding mechanisms.
[4] A part of the outer wall of the jig body constituting the air bleeding mechanism has a shape in which the outer wall surface is close to the through hole so as to lose the continuity of the appearance shape of the jig body, [2] or The filter jig according to [3].
[5] The filter jig according to [4], wherein a part of the outer wall of the jig body constituting the air bleeding mechanism has a shape in which a part of the jig body is missing.
[6] One of [1] to [5], which has an engaging portion that engages with a storage container that stores the liquid that has passed through the through hole on at least one end side of the through hole of the jig body. The filter jig described.
[7] The filter jig according to [6], wherein the engaging portion engages with the outside of the storage container.
[8] The filter jig according to [6] or [7], wherein the engaging portion has a recess that engages with the storage container.
[9] The filter jig according to any one of [6] to [8], wherein the engaging portion has one or more notches in the outer peripheral direction of the through hole of the jig body.
[10] The filter jig according to any one of [6] to [9], wherein the insertion position of the storage container into the engaging portion and the position of the air bleeding mechanism coincide with each other in the outer peripheral direction of the through hole. ..
[11] The method according to any one of [1] to [10], wherein the through hole of the jig body has a diameter-expanded portion that expands in the direction from the filter toward the end, corresponding to at least one end. Filter jig.
[12] When viewed from the penetrating direction of the through hole of the jig body, an air bleeding mechanism provided on one end side of the through hole from the filter and an air bleeding mechanism provided on the other end side of the through hole from the filter. The filter jig according to any one of [1] to [11], wherein the air bleeding mechanism is opposed to the air bleeding mechanism with a through hole interposed therebetween.
[13] A sampling method using the filter jig according to any one of [1] to [12], after passing the liquid to be treated through the through hole of the jig body.
A sampling method in which the residue on the filter is recovered by passing the recovery liquid through the through hole of the jig body in the direction opposite to the flow direction of the liquid to be treated.
[14] With one end of the through hole of the jig body facing up and the other end facing down, at least one of the liquid to be treated and the liquid to be recovered is passed by dropping. , [13].

本発明によれば、残渣中に目的物が存在する濾過において、濾過を円滑かつ迅速に行えると共に、目的物を高い回収率（高濃度）で容易に回収でき、しかも、目的物の損傷も防止できる。 According to the present invention, in filtration in which the target product is present in the residue, the filtration can be performed smoothly and quickly, the target product can be easily recovered at a high recovery rate (high concentration), and damage to the target product is prevented. can.

本発明のフィルター治具の一例の概略側面図である。It is a schematic side view of an example of the filter jig of this invention. 図１に示すフィルター治具の概略正面図である。It is a schematic front view of the filter jig shown in FIG. 図１に示すフィルター治具の部分斜視図である。It is a partial perspective view of the filter jig shown in FIG. 本発明のフィルター治具の別の例の概略側面図である。It is a schematic side view of another example of the filter jig of this invention. 本発明のフィルター治具に用いられる液受け容器の一例の概略図である。It is the schematic of an example of the liquid receiving container used for the filter jig of this invention. 本発明のフィルター治具に用いられる回収容器の一例の概略図である。It is the schematic of an example of the collection container used for the filter jig of this invention. 図１に示すフィルター治具を説明するための概略斜視図である。It is a schematic perspective view for demonstrating the filter jig shown in FIG. 図１に示すフィルター治具の作用を説明するための概略側面図である。It is a schematic side view for demonstrating the operation of the filter jig shown in FIG. 本発明のフィルター治具の別の例を説明するための概念図である。It is a conceptual diagram for demonstrating another example of the filter jig of this invention. 本発明のフィルター治具の別の例の概略正面図である。It is a schematic front view of another example of the filter jig of this invention.

以下、本発明のフィルター治具およびサンプリング方法について、添付の図面に示される好適実施例を基に詳細に説明する。
なお、以下に示す全ての図は、あくまで、本発明を説明するために、本発明のフィルター治具の一例を概念的に示す図である。従って、各部材の位置関係、大きさ、および、形状等は、実際の本発明のフィルター治具とは異なる。 Hereinafter, the filter jig and the sampling method of the present invention will be described in detail based on the preferred examples shown in the accompanying drawings.
It should be noted that all the figures shown below are diagrams conceptually showing an example of the filter jig of the present invention in order to explain the present invention. Therefore, the positional relationship, size, shape, etc. of each member are different from the actual filter jig of the present invention.

図１に、本発明のフィルター治具の側面図を、図２に、図１に示すフィルター治具の正面図を、図３に図１に示すフィルター治具の部分斜視図を、それぞれ、概念的に示す。図２は、本発明のフィルター治具を、図１中における左側から観察した図である。 FIG. 1 is a side view of the filter jig of the present invention, FIG. 2 is a front view of the filter jig shown in FIG. 1, and FIG. 3 is a partial perspective view of the filter jig shown in FIG. Shown. FIG. 2 is a view of the filter jig of the present invention observed from the left side in FIG.

図示例のフィルター治具１０は、第１部材１２と、第２部材１４と、フィルター１６とを有する。第１部材１２および第２部材１４は、本発明のフィルター治具１０における治具本体１８を構成する。
なお、第１部材１２および第２部材１４は、同じ物である。従って、同じ部材（部位）には、同じ符号を付す。 The filter jig 10 of the illustrated example has a first member 12, a second member 14, and a filter 16. The first member 12 and the second member 14 constitute a jig body 18 in the filter jig 10 of the present invention.
The first member 12 and the second member 14 are the same. Therefore, the same members (parts) are designated by the same reference numerals.

本発明のフィルター治具１０は、基本的に、フィルター１６によって濾別した残渣に目的物が存在する場合に対応して、被処理液（処理を行う液体）の濾過を行うものである。
このような本発明のフィルター治具１０は、医療等の研究および病気の治療等における細胞の分離および細胞の篩分け、各種生体の成体と幼体とのふるい分け、シリコーン粒子等の粒子が分散している液体からの粒子の回収、および、ロッドや平板などの異形無機粒子と球粒子との分別等、濾過を行う全ての用途に利用可能である。
後述するが、本発明のフィルター治具（サンプリング方法）は、重力による濾過を円滑に行えると共に、目的物（残渣）を高い回収率（高濃度）で容易に回収でき、目的物の損傷も防止できる。この点を考慮すると、本発明のフィルター治具（サンプリング方法）は、検査を含む医療用途には、好適に利用される。 The filter jig 10 of the present invention basically filters the liquid to be treated (the liquid to be treated) in response to the presence of the target substance in the residue filtered by the filter 16.
In such a filter jig 10 of the present invention, in research such as medical treatment and treatment of diseases, cell separation and cell sieving, sieving of adult and juveniles of various living bodies, particles such as silicone particles are dispersed. It can be used for all purposes of filtration, such as recovery of particles from existing liquids and separation of deformed inorganic particles such as rods and flat plates from spherical particles.
As will be described later, the filter jig (sampling method) of the present invention can smoothly perform filtration by gravity, easily recover the target product (residue) at a high recovery rate (high concentration), and prevent damage to the target product. can. Considering this point, the filter jig (sampling method) of the present invention is suitably used for medical applications including inspection.

第１部材１２および第２部材１４は、軸線方向（中心線方向）に略円筒状の貫通孔２０を有する円錐台の下底側の端部にフランジを設けてなる、略円錐台形状の部材である。なお、下底とは、円錐台における、大径側の面である。
なお、第１部材１２および第２部材１４の形成材料には、制限はなく、処理する被処理液等に応じて、十分な耐性を有する材料を、適宜、選択すればよい。一例として、ポリプロピレン、ポリエチレン、ポリエチレンテレフタレート、および、ポリテトラフルオロエチレン等の樹脂材料が例示される。 The first member 12 and the second member 14 are substantially truncated cone-shaped members having flanges at the lower bottom end of the truncated cone having a substantially cylindrical through hole 20 in the axial direction (center line direction). Is. The lower base is a surface on the large diameter side of the truncated cone.
The materials for forming the first member 12 and the second member 14 are not limited, and a material having sufficient resistance may be appropriately selected depending on the liquid to be treated and the like. As an example, resin materials such as polypropylene, polyethylene, polyethylene terephthalate, and polytetrafluoroethylene are exemplified.

第１部材１２と第２部材１４とは、上底を対面して、フィルター１６を挟んで当接されて、液密に接合される。この第１部材１２と第２部材１４との接合によって、本発明のフィルター治具における、貫通孔を有する治具本体１８が構成される。図示例のフィルター冶具１０の第１部材１２および第２部材１４において、上底側は、フィルター１６側であり、下底側は、フィルター１６とは逆側である。第１部材１２および第２部材１４において、下底側は、後述する被処理液または回収液の流入口（または流出口）となる。
なお、第１部材１２と第２部材１４の接合方法には制限はなく、接着剤を用いる方法、粘着剤を用いる方法、治具を用いる方法、凹凸を嵌合する方法、ネジ止め、ボルトとナットとによる締結、粘着テープによる接合等、貫通孔を有する複数の部材を、貫通孔が連通するように液密に接合できる公知の方法が、全て利用可能である。
また、必要に応じて、第１部材１２と第２部材１４との間には、両者を液密に接合するためのパッキンを設けてもよい。 The first member 12 and the second member 14 face each other with the upper bottom facing each other, are brought into contact with each other with the filter 16 interposed therebetween, and are liquidtightly joined. By joining the first member 12 and the second member 14, the jig body 18 having a through hole in the filter jig of the present invention is configured. In the first member 12 and the second member 14 of the filter jig 10 of the illustrated example, the upper bottom side is the filter 16 side, and the lower bottom side is the opposite side to the filter 16. In the first member 12 and the second member 14, the lower bottom side serves as an inlet (or outlet) for the liquid to be treated or the recovered liquid, which will be described later.
The method of joining the first member 12 and the second member 14 is not limited, and the method of using an adhesive, the method of using an adhesive, the method of using a jig, the method of fitting unevenness, screwing, and bolts are used. All known methods that can join a plurality of members having through-holes in a liquid-tight manner so that the through-holes communicate with each other, such as fastening with a nut and joining with an adhesive tape, can be used.
Further, if necessary, a packing for liquid-tightly joining the first member 12 and the second member 14 may be provided.

なお、本発明のフィルター治具において、治具本体は、２つの部材を接合して構成されるのに制限はされない。すなわち、本発明のフィルター治具では、１つの部材によって、貫通孔を有する治具本体を構成してもよく、または、３個以上の部材を組み合わせて上述したような公知の方法で接合することで、貫通孔を有する治具本体を構成してもよい。
１つの部材または３個以上の部材を組み合わせて、貫通孔を有する治具本体を構成する場合には、公知の各種の方法で、貫通孔の途中に、貫通孔を閉塞するようにフィルター１６を設ければよい。本発明において、冶具本体を１つの部材で構成する場合には、射出成型等によって第１部材１２と第２部材１４とフィルター１６とを一体化して成型した構成であってもよい。また、冶具本体を複数の部材で構成する場合でも、射出成型等によって、1つの部材とフィルター１６とを一体化して成型してもよい。
また、本発明のフィルター治具において、治具本体の形状は、２つの略円錐台形状の部材を上底側で当接した形状にも制限はされない。本発明のフィルター治具において、治具本体の形状は、円筒状でも、楕円筒状でも、六角筒等の角筒状でも、立方体または直方体に貫通孔を設けたような形状でもよい。すなわち、本発明のフィルター治具において、治具本体は、濾過する被処理液を通液する貫通孔を有するものであれば、各種の形状が利用可能である。 In the filter jig of the present invention, the jig body is not limited to being formed by joining two members. That is, in the filter jig of the present invention, a jig body having a through hole may be formed by one member, or three or more members may be combined and joined by a known method as described above. Therefore, a jig body having a through hole may be configured.
When a jig body having a through hole is formed by combining one member or three or more members, a filter 16 is used in various known methods so as to close the through hole in the middle of the through hole. It may be provided. In the present invention, when the jig main body is composed of one member, the first member 12, the second member 14, and the filter 16 may be integrally molded by injection molding or the like. Further, even when the jig main body is composed of a plurality of members, one member and the filter 16 may be integrally molded by injection molding or the like.
Further, in the filter jig of the present invention, the shape of the jig body is not limited to the shape in which two substantially truncated cone-shaped members are in contact with each other on the upper bottom side. In the filter jig of the present invention, the shape of the jig body may be a cylindrical shape, an elliptical cylinder shape, a square cylinder shape such as a hexagonal cylinder, or a shape in which a through hole is provided in a cube or a rectangular parallelepiped. That is, in the filter jig of the present invention, various shapes can be used as long as the jig body has a through hole for passing the liquid to be filtered.

第１部材１２と第２部材１４との間には、第１部材１２と第２部材１４を組み合わせて構成された治具本体１８の貫通孔を閉塞するように、フィルター１６が設けられる。
フィルター１６は、フィルター治具１０によって被処理液の濾過を行うためのフィルターであり、被処理液の種類等に応じて、各種の液体の濾過を行うための公知のフィルター（濾過材）が、全て、利用可能である。 A filter 16 is provided between the first member 12 and the second member 14 so as to close the through hole of the jig main body 18 formed by combining the first member 12 and the second member 14.
The filter 16 is a filter for filtering the liquid to be treated by the filter jig 10, and a known filter (filter material) for filtering various liquids depending on the type of the liquid to be treated and the like can be used. All are available.

フィルター１６のメッシュサイズ（孔径）は、濾過（濾別）によって回収する目的物に応じて、適宜、選択すればよい。
さらに、フィルター１６の大きさ、および、フィルター治具１０の大きさにも、制限はなく、フィルター治具１０の用途、濾過を行う被処理液の種類、濾過を行う被処理液の量、濾別する残渣、および、想定される残渣の量等に応じて、適宜、設定すればよい。 The mesh size (pore diameter) of the filter 16 may be appropriately selected according to the object to be collected by filtration (filter separation).
Further, the size of the filter 16 and the size of the filter jig 10 are not limited, and the use of the filter jig 10, the type of the liquid to be filtered, the amount of the liquid to be filtered, and the filter are not limited. It may be appropriately set according to the amount of the residue to be separated and the expected amount of the residue.

図１〜図３に示すように、第１部材１２および第２部材１４は、後述するフランジ部２６を含んで、筒状の円錐台の外壁（外周面）の一部を下底から上底に向かって、すなわち、フィルター１６とは逆側からフィルター１６側に向かって、途中まで切り欠いたような形状を有し、この切り欠き部が、エア抜き機構２４を構成する。言い換えれば、第１部材１２は、下底にフランジ部を有する筒状の円錐台を形成する壁の外壁側の一部を、下底から上底の途中まで欠損したような形状を有し、この欠損部が、エア抜き機構２４を構成する。
前述のように、第１部材１２と第２部材１４とは、上底側を当接して、フィルター１６を挟んで接合され、治具本体１８が構成される。従って、治具本体１８において、エア抜き機構２４は、フィルター１６よりも貫通孔の端部側の両側に、設けられる。なお、貫通孔の端部とは、貫通孔の貫通方向の端部である。
エア抜き機構２４に関しては、後に詳述する。 As shown in FIGS. 1 to 3, the first member 12 and the second member 14 include a flange portion 26 described later, and a part of the outer wall (outer peripheral surface) of the cylindrical truncated cone is formed from a lower bottom to an upper bottom. That is, from the side opposite to the filter 16 toward the filter 16 side, it has a shape that is cut out halfway, and this cutout portion constitutes the air bleeding mechanism 24. In other words, the first member 12 has a shape in which a part of the outer wall side of the wall forming the cylindrical truncated cone having a flange portion on the lower base is missing from the lower bottom to the middle of the upper bottom. This defective portion constitutes the air bleeding mechanism 24.
As described above, the first member 12 and the second member 14 are brought into contact with each other on the upper bottom side and joined with the filter 16 interposed therebetween to form the jig body 18. Therefore, in the jig main body 18, the air bleeding mechanism 24 is provided on both sides of the through hole on both sides of the filter 16. The end of the through hole is the end of the through hole in the penetrating direction.
The air bleeding mechanism 24 will be described in detail later.

前述のように、第１部材１２および第２部材１４は、略円筒状の貫通孔２０を有する。貫通孔２０は、濾過を行う被処理液の流路となる。
貫通孔２０すなわち治具本体１８の貫通孔は、略円筒状に制限はされない。すなわち、貫通孔２０は、楕円筒状でも、三角筒、四角筒および六角筒等の角筒状であってもよい。しかしながら、角部への粒子等の付着を防止できる、デッドスペースを無くせる等の点で、貫通孔２０は、楕円筒状および円筒状が好ましい。 As described above, the first member 12 and the second member 14 have a substantially cylindrical through hole 20. The through hole 20 serves as a flow path for the liquid to be filtered.
The through hole 20, that is, the through hole of the jig body 18, is not limited to a substantially cylindrical shape. That is, the through hole 20 may have an elliptical cylinder shape or a square cylinder shape such as a triangular cylinder, a square cylinder, and a hexagonal cylinder. However, the through hole 20 is preferably oval-cylindrical or cylindrical in terms of preventing particles and the like from adhering to the corners and eliminating dead space.

図１および図３に示すように、図示例のフィルター治具１０において、第１部材１２および第２部材１４の貫通孔２０は、好ましい態様として、下底側の端部すなわちフィルター１６とは逆側の端部に、下底側の端部に向かって拡径する、拡径部２０ａを有する。すなわち、フィルター治具１０は、治具本体１８において、貫通孔の両端部に、拡径部２０ａを有する。
後述するが、フィルター治具１０においては、第１部材１２および第２部材１４の貫通孔２０下底側の端部が、被処理液の流入口、および、被処理液の濾過によって濾別した残渣を回収するための回収液の流入口になる。従って、流入口に、このような拡径部２０ａを有することにより、フィルター１６による濾過面積に比して、被処理液および回収液の入口を大きくできるので、作業性を向上できる。
また、フィルター１６による濾過面積は、フィルター治具１０の用途に応じて決定され、他方、第１部材１２および第２部材１４の下底側の大きさは、基本的に、フィルター治具１０に係合させる、液体を収容する収容容器の大きさによって決まる。従って、このような拡径部２０ａを有することにより、フィルター１６による濾過面積によらず、貫通孔２０への液体の流入口の大きさを、収容容器に合わせることが可能になる。 As shown in FIGS. 1 and 3, in the filter jig 10 of the illustrated example, the through hole 20 of the first member 12 and the second member 14 is preferably opposite to the lower bottom end portion, that is, the filter 16. At the end on the side, there is a diameter-expanded portion 20a that expands in diameter toward the end on the lower bottom side. That is, the filter jig 10 has enlarged diameter portions 20a at both ends of the through holes in the jig main body 18.
As will be described later, in the filter jig 10, the ends of the first member 12 and the second member 14 on the lower bottom side of the through hole 20 are filtered by the inflow port of the liquid to be treated and the filtration of the liquid to be treated. It serves as an inflow port for the recovery liquid for recovering the residue. Therefore, by having such an enlarged diameter portion 20a at the inflow port, the inlets of the liquid to be treated and the recovered liquid can be made larger than the filtration area by the filter 16, so that workability can be improved.
Further, the filtration area by the filter 16 is determined according to the use of the filter jig 10, while the size of the lower bottom side of the first member 12 and the second member 14 is basically determined by the filter jig 10. It depends on the size of the containment container to be engaged with and which contains the liquid. Therefore, by having such an enlarged diameter portion 20a, the size of the inflow port of the liquid into the through hole 20 can be adjusted to the storage container regardless of the filtration area by the filter 16.

なお、このような拡径部２０ａは、第１部材１２および第２部材１４の一方のみが有するものであってもよい。すなわち、拡径部は、治具本体１８の貫通孔の一方の端部のみが有してもよい。
しかしながら、後述するが、本発明のフィルター治具１０は、被処理液の濾過を行った後、濾過とは逆方向に回収液を流して、フィルター１６で濾別した残渣を回収する。従って、作業性を考慮すると、拡径部２０ａは、第１部材１２および第２部材１４の両方、すなわち、治具本体の貫通孔の両端部に設けるのが好ましい。 It should be noted that such an enlarged diameter portion 20a may be provided only by one of the first member 12 and the second member 14. That is, the enlarged diameter portion may be provided only at one end of the through hole of the jig main body 18.
However, as will be described later, in the filter jig 10 of the present invention, after filtering the liquid to be treated, the recovery liquid is flowed in the direction opposite to the filtration, and the residue filtered by the filter 16 is recovered. Therefore, in consideration of workability, it is preferable that the enlarged diameter portions 20a are provided on both the first member 12 and the second member 14, that is, at both ends of the through holes of the jig body.

本発明の貫通孔２０の拡径部２０ａは、貫通孔２０の下底側の端部すなわちフィルター１６とは逆側の端部（液体の流入口）のみに設ける構成に制限はされない。
例えば、図４に概念的に示すように、第１部材１２および第２部材１４の貫通孔２０は、全域が、上底から下底に向かって、すなわち、フィルター１６から治具本体１８における被処理液および回収液の流入口に向かって、漸次、拡径していてもよい。また、図４に示すような、全域が上底から下底に向かって、漸次、拡径する貫通孔でも、下底側（液の流入口側）の端部に、図２等と同様の、より大きく径が広がる拡径部２０ａを有してもよい。このような構成を有することにより、上述した利点に加え、被処理液の濾過による残渣の回収液による回収を容易にし、さらに、回収液の量も少くし、残渣を回収した回収液における目的物の濃度を高くできる。
あるいは、貫通孔２０の下底側の端部に、同様の拡径部２０ａを有し、かつ、貫通孔２０が、拡径部２０ａの下底側の端部から上底に向かって、すなわち、液体の流入口側からフィルター１６に向かって、漸次、拡径してもよい。なお、この液体の流入口側からフィルター１６に向かう拡径は、全域でも部分的でもよい。または、貫通孔２０は、全域が同じ径であってもよい。
本発明において、第１部材１２および第２部材１４の貫通孔２０の下底側の径、すなわち、冶具本体１８における被処理液等の流入口の径は、基本的に回収容器３４等の径で決まるが、大きい方が作業性を良好にできる。他方、第１部材１２および第２部材１４の貫通孔２０の上底側の径、すなわち、フィルター冶具におけるフィルター１６の大きさは、大きい方が被処理液の濾過は容易になるが、大きすぎると、残渣の回収に必要な回収液の量が多くなってしまう。 The enlarged diameter portion 20a of the through hole 20 of the present invention is not limited to the configuration provided only at the lower bottom side end portion of the through hole 20, that is, the end portion (liquid inlet) opposite to the filter 16.
For example, as conceptually shown in FIG. 4, the entire through hole 20 of the first member 12 and the second member 14 is covered from the upper bottom to the lower bottom, that is, from the filter 16 to the jig body 18. The diameter may be gradually increased toward the inlet of the treatment liquid and the recovery liquid. Further, even in a through hole whose entire diameter gradually expands from the upper bottom to the lower bottom as shown in FIG. 4, the same as in FIG. , It may have a diameter-expanded portion 20a having a larger diameter. By having such a configuration, in addition to the above-mentioned advantages, the recovery of the residue by filtration of the liquid to be treated is facilitated, the amount of the recovery liquid is also reduced, and the target product in the recovery liquid in which the residue is recovered. Can be increased in concentration.
Alternatively, the through hole 20 has a similar enlarged diameter portion 20a at the lower bottom side end portion, and the through hole 20 is directed from the lower bottom side end portion of the enlarged diameter portion 20a toward the upper bottom, that is, , The diameter may be gradually increased from the liquid inlet side toward the filter 16. The diameter of the liquid from the inlet side toward the filter 16 may be expanded over the entire area or partially. Alternatively, the through hole 20 may have the same diameter in the entire area.
In the present invention, the diameter of the lower bottom side of the through hole 20 of the first member 12 and the second member 14, that is, the diameter of the inflow port of the liquid to be treated in the jig main body 18, is basically the diameter of the collection container 34 or the like. However, the larger the size, the better the workability. On the other hand, the larger the diameter of the upper bottom side of the through hole 20 of the first member 12 and the second member 14, that is, the size of the filter 16 in the filter jig, the easier it is to filter the liquid to be treated, but it is too large. As a result, the amount of recovery liquid required for recovery of the residue increases.

第１部材１２および第２部材１４は、共に、下底側の端部すなわちフィルター１６とは逆側の端部に、円錐台の下底から外方に突出するように、平板状のフランジ部２６（鍔部２６）を有する。
また、第１部材１２および第２部材１４には、好ましい態様として、フランジ部２６の下面（フィルター１６と逆側面）には、係合部３０が設けられる。
以下の説明では、第１部材１２および第２部材１４におけるフィルター１６と逆側を、『下』とも言う。 Both the first member 12 and the second member 14 have flat flange portions so as to project outward from the lower bottom of the truncated cone at the lower bottom side end, that is, the end opposite to the filter 16. It has 26 (flange part 26).
Further, as a preferred embodiment, the first member 12 and the second member 14 are provided with an engaging portion 30 on the lower surface (opposite side surface to the filter 16) of the flange portion 26.
In the following description, the side of the first member 12 and the second member 14 opposite to the filter 16 is also referred to as "lower".

第１部材１２および第２部材１４のフランジ部２６は、上述したエア抜き機構２４に対応する領域において、第１部材１２および第２部材１４における円錐台形状の部分の外壁と同一面となるように、切り欠かれた状態（欠損した状態）となっており、このフランジ部２６の切り欠かれた領域も、エア抜き機構２４の一部を構成する。 The flange portion 26 of the first member 12 and the second member 14 is flush with the outer wall of the truncated cone-shaped portion of the first member 12 and the second member 14 in the region corresponding to the air bleeding mechanism 24 described above. In addition, it is in a notched state (missing state), and the notched region of the flange portion 26 also constitutes a part of the air bleeding mechanism 24.

係合部３０は、下側（フィルター１６と逆側）の端部が内側に突出する略Ｌ字状の断面を有するもので、フランジ部２６の輪の外側に沿う形状を有する。すなわち、係合部３０は、内側に、フランジ部２６の輪に沿うように凹部（溝部）を有する。
図１〜図３に示すように、係合部３０は、フランジ部２６の周方向に、エア抜き機構２４の中心から、９０°の回転角で中心が位置するように、３個所に設けられる。従って、係合部３０の１個所は、エア抜き機構２４と対向して、エア抜き機構２４と共に貫通孔２０を挟む位置に設けられる。 The engaging portion 30 has a substantially L-shaped cross section in which the lower end (opposite to the filter 16) projects inward, and has a shape along the outside of the ring of the flange portion 26. That is, the engaging portion 30 has a recess (groove portion) inside along the ring of the flange portion 26.
As shown in FIGS. 1 to 3, the engaging portions 30 are provided at three positions in the circumferential direction of the flange portion 26 so that the center is located at a rotation angle of 90 ° from the center of the air bleeding mechanism 24. .. Therefore, one part of the engaging portion 30 is provided at a position facing the air bleeding mechanism 24 and sandwiching the through hole 20 together with the air bleeding mechanism 24.

後述するが、本発明のフィルター治具１０は、発明における収容容器である液受け容器３２を装着して、液受け容器３２と逆側の貫通孔２０から被処理液を流入して、被処理液の濾過を行う。次いで、液受け容器３２と逆側に、本発明における収容容器である回収容器３４を装着して、液受け容器３２を取り外して、こちら側から回収液を流入し、被処理液の濾過とは逆に回収液を流すことで、フィルター１６で濾別した残渣を回収容器３４に回収する（図８参照）。なお、濾液が不要である場合には、液受け容器３２は、必ずしも装着する必要はなく、濾液を、直接、廃棄してもよい。
図５および図６（図７および図８も参照）に概念的に示すように、液受け容器３２および回収容器３４は、共に、一方の端面が閉塞する略円筒状の容器である。液受け容器３２は、液体の流入口となる開放端に対応して、外方向に突出するフランジ３２ａを有する。同様に、回収容器３４も、液体の流入口となる開放端に対応して、外方向に突出するフランジ３４ａを有する。 As will be described later, the filter jig 10 of the present invention is equipped with the liquid receiving container 32 which is the storage container of the present invention, and the liquid to be treated flows in from the through hole 20 on the opposite side of the liquid receiving container 32 to be treated. Filter the liquid. Next, the recovery container 34, which is the storage container in the present invention, is attached to the opposite side of the liquid receiving container 32, the liquid receiving container 32 is removed, and the recovered liquid flows in from this side. On the contrary, by flowing the recovery liquid, the residue filtered by the filter 16 is recovered in the recovery container 34 (see FIG. 8). When the filtrate is not required, the liquid receiving container 32 does not necessarily have to be attached, and the filtrate may be directly discarded.
As conceptually shown in FIGS. 5 and 6 (see also FIGS. 7 and 8), both the liquid receiving container 32 and the collecting container 34 are substantially cylindrical containers in which one end face is closed. The liquid receiving container 32 has a flange 32a that projects outward, corresponding to an open end that serves as a liquid inlet. Similarly, the recovery container 34 also has a flange 34a that projects outward, corresponding to the open end that serves as the inflow port for the liquid.

図７に回収容器３４を例示して示すように、フィルター治具１０では、エア抜き機構２４側から、係合部３０の凹部に回収容器３４（液受け容器３２）のフランジ３４ａ（フランジ３２ａ）を挿入することで、フィルター治具１０に回収容器３４を装着する。回収容器３４は、フランジ３４ａが、エア抜き機構２４と対向する位置に設けられる係合部３０の凹部に挿入され、かつ、係合部３０のフランジ部２６からの立設部に当接するまで、押し込まれる。これにより、フィルター治具１０に装着する回収容器３４の位置決めを行うことができる。
フィルター治具１０の係合部３０は、内方に突出する下側の端部と第１部材１２（第２部材１４）のフランジ部２６とで、回収容器３４のフランジ３４ａを厚さ方向に挟み、かつ、貫通孔２０を挟んで対向する２つの係合部３０によって、回収容器３４のフランジ３４ａを直径方向に挟む。
フィルター治具１０は、これにより、係合部３０と回収容器３４のフランジ３４ａとを、緩く嵌合して、回収容器３４を装着し、かつ、保持する。 As shown by exemplifying the recovery container 34 in FIG. 7, in the filter jig 10, the flange 34a (flange 32a) of the recovery container 34 (liquid receiving container 32) is placed in the recess of the engaging portion 30 from the air bleeding mechanism 24 side. Is inserted to attach the collection container 34 to the filter jig 10. In the collection container 34, until the flange 34a is inserted into the recess of the engaging portion 30 provided at a position facing the air bleeding mechanism 24 and comes into contact with the vertical portion of the engaging portion 30 from the flange portion 26. Be pushed in. As a result, the collection container 34 to be mounted on the filter jig 10 can be positioned.
The engaging portion 30 of the filter jig 10 is a lower end portion protruding inward and a flange portion 26 of the first member 12 (second member 14), and the flange 34a of the collection container 34 is set in the thickness direction. The flange 34a of the collection container 34 is sandwiched in the radial direction by the two engaging portions 30 that are sandwiched and that face each other with the through hole 20 in between.
As a result, the filter jig 10 loosely fits the engaging portion 30 and the flange 34a of the recovery container 34, and mounts and holds the recovery container 34.

フィルター治具１０は、好ましい態様として、このような係合部３０を有することにより、液受け容器３２および回収容器３４を位置決めして装着し、かつ、保持できる。以下の説明では、液受け容器３２および回収容器３４をまとめて、『容器』とも言う。
そのため、フィルター治具１０によれば、被処理液の濾過および残渣の回収を行っている最中に、作業者が、フィルター治具１０と容器とを位置決めして保持する必要がなく、作業性を大幅に向上できる。また、被処理液の濾過および残渣の回収を行っている最中に、フィルター治具１０から液受け容器３２および回収容器３４が不用意に外れることも防止できる。
また、フィルター治具１０の係合部３０は、好ましい態様として。液受け容器３２および回収容器３４の外側に係合して、容器を保持する。外側から係合して容器を保持することにより、フィルター治具を容器の内側（液体の収容部）に係合して容器を装着する場合に比して、容器を確実に保持することができ、例えば容器を装着されたフィルター治具１０が横転した場合等における容器の脱落を、好適に防止できる。
なお、本発明のフィルター治具において、液受け容器３２および回収容器３４を位置決めして保持するための係合部は、容器の外側に係合する構成に制限はされない。すなわち、本発明のフィルター治具は、液受け容器３２および回収容器３４の内側に係合して、容器を保持する係合部を有する構成であってもよい。 As a preferred embodiment, the filter jig 10 can position, mount, and hold the liquid receiving container 32 and the collecting container 34 by having such an engaging portion 30. In the following description, the liquid receiving container 32 and the collecting container 34 are collectively referred to as a “container”.
Therefore, according to the filter jig 10, it is not necessary for the operator to position and hold the filter jig 10 and the container during the filtration of the liquid to be treated and the recovery of the residue, and the workability is improved. Can be greatly improved. Further, it is possible to prevent the liquid receiving container 32 and the recovery container 34 from being inadvertently removed from the filter jig 10 during the filtration of the liquid to be treated and the recovery of the residue.
Further, the engaging portion 30 of the filter jig 10 is a preferred embodiment. It engages with the outside of the liquid receiving container 32 and the collecting container 34 to hold the container. By engaging from the outside to hold the container, the container can be held more reliably than when the filter jig is engaged with the inside of the container (liquid accommodating portion) to mount the container. For example, when the filter jig 10 to which the container is mounted rolls over, the container can be suitably prevented from falling off.
In the filter jig of the present invention, the engaging portion for positioning and holding the liquid receiving container 32 and the collecting container 34 is not limited to the configuration in which the liquid receiving container 32 and the collecting container 34 are engaged with the outside of the container. That is, the filter jig of the present invention may be configured to have an engaging portion that engages inside the liquid receiving container 32 and the collecting container 34 to hold the container.

図示例のフィルター治具１０において、第１部材１２および第２部材１４は、フランジ部２６の周方向に分割された、３つの係合部３０を有する。
本発明のフィルター治具は、これに制限はされず、例えば、３つの係合部３０をフランジ部２６の周方向に接続したような、１個の係合部を有する構成でもよい。
しかしながら、液受け容器３２および回収容器３４と係合して、容器を保持する係合部３０は、図示例のように、フランジ部の周方向（貫通孔２０の外周方向）に分割して、複数個を設けることにより、係合部３０に容器のフランジ部を嵌合した際に係合部３０が広がることが可能になる。そのため、周方向に複数の係合部３０を設けることにより、係合部３０（フィルター治具１０）と、容器とを、適度な嵌合力で係合することができ、その結果、フィルター治具１０への容器の着脱を容易かつ円滑に行うことを可能にし、かつ、フィルター治具１０に装着した容器が不要に脱落することも好適に防止できる。 In the filter jig 10 of the illustrated example, the first member 12 and the second member 14 have three engaging portions 30 divided in the circumferential direction of the flange portion 26.
The filter jig of the present invention is not limited to this, and may have a configuration having one engaging portion, for example, three engaging portions 30 connected in the circumferential direction of the flange portion 26.
However, the engaging portion 30 that engages with the liquid receiving container 32 and the collecting container 34 and holds the container is divided in the circumferential direction of the flange portion (outer peripheral direction of the through hole 20) as shown in the illustrated example. By providing a plurality of the engaging portions, the engaging portion 30 can be expanded when the flange portion of the container is fitted to the engaging portion 30. Therefore, by providing a plurality of engaging portions 30 in the circumferential direction, the engaging portion 30 (filter jig 10) and the container can be engaged with an appropriate fitting force, and as a result, the filter jig It is possible to easily and smoothly attach / detach the container to / from the filter jig 10, and it is also possible to preferably prevent the container attached to the filter jig 10 from being unnecessarily dropped off.

係合部３０は、第１部材１２および第２部材１４の一方のみが有するものであってもよい。すなわち、係合部３０は、治具本体１８の貫通孔の一方の端部のみに対応して設けてもよい。
しかしながら、後述するが、本発明のフィルター治具１０は、被処理液の濾過を行った後、逆方向に回収液を流して、濾過によって濾別した残渣を回収容器に回収する。従って、作業性を考慮すると、係合部３０は、第１部材１２および第２部材１４の両方、すなわち、治具本体１８の貫通孔の両端部に対応して設けるのが好ましい。
また、第１部材１２および第２部材１４の係合部３０、すなわち、治具本体１８の貫通孔の両端の係合部は、図示例のように同じ構成を有するのに制限はされず、異なる構成であってもよい。 The engaging portion 30 may be held by only one of the first member 12 and the second member 14. That is, the engaging portion 30 may be provided corresponding to only one end of the through hole of the jig main body 18.
However, as will be described later, in the filter jig 10 of the present invention, after filtering the liquid to be treated, the recovery liquid is flowed in the reverse direction, and the residue filtered by filtration is collected in the recovery container. Therefore, in consideration of workability, it is preferable that the engaging portion 30 is provided corresponding to both the first member 12 and the second member 14, that is, both ends of the through holes of the jig body 18.
Further, the engaging portions 30 of the first member 12 and the second member 14, that is, the engaging portions at both ends of the through holes of the jig body 18, are not limited to having the same configuration as shown in the illustrated example. It may have a different configuration.

以下、図８を参照して、本発明のフィルター治具１０の作用、すなわち、本発明のサンプリング方法を説明することにより、本発明について、より詳細に説明する。 Hereinafter, the present invention will be described in more detail by explaining the operation of the filter jig 10 of the present invention, that is, the sampling method of the present invention with reference to FIG.

上述したように、本発明のフィルター治具１０は、基本的に、濾別した残渣に目的物が存在する濾過に利用されるものである。
本発明のフィルター治具１０を用いて被処理液の濾過、すなわち、目的物の濾別を行う場合には、まず、第２部材１４（または第１部材１２）のエア抜き機構２４側から、係合部３０の凹部に液受け容器３２のフランジ３２ａを挿入させて、図８の左側に示すように、フィルター治具１０（治具本体１８）に、液受け容器３２を装着する。なお、濾液が不要である場合には、液受け容器３２を装着せずに、濾液を、そのまま廃棄してもよいのは、前述のとおりである。 As described above, the filter jig 10 of the present invention is basically used for filtration in which the target substance is present in the filtered residue.
When filtering the liquid to be treated using the filter jig 10 of the present invention, that is, filtering the target object, first, from the air bleeding mechanism 24 side of the second member 14 (or the first member 12), The flange 32a of the liquid receiving container 32 is inserted into the recess of the engaging portion 30, and the liquid receiving container 32 is attached to the filter jig 10 (jig main body 18) as shown on the left side of FIG. As described above, when the filtrate is not required, the filtrate may be discarded as it is without attaching the liquid receiving container 32.

次いで、液受け容器３２を下方にして、第１部材１２の貫通孔２０に被処理液を流入させ、被処理液の濾過を行う。
ここで、図８（図３および図７も参照）に示すように、第２部材１４は、外壁の一部を切り欠いた形状、すなわち、第２部材１４（治具本体１８）の外壁の一部を欠損した形状のエア抜き機構２４を有する。そのため、フィルター治具１０（第２部材１４）は、液受け容器３２を装着された状態で、液受け容器３２における液体の流入口の全面を覆わず、液受け容器３２の流入口の一部が外部に開口した状態となる。
そのため、このエア抜き機構２４によって開口された部分が、エア抜きとして作用するので、重力落下（自重落下）による濾過でも、円滑かつ迅速に濾過を行うことができる。 Next, with the liquid receiving container 32 facing downward, the liquid to be treated flows into the through hole 20 of the first member 12, and the liquid to be treated is filtered.
Here, as shown in FIG. 8 (see also FIGS. 3 and 7), the second member 14 has a shape in which a part of the outer wall is cut out, that is, the outer wall of the second member 14 (jig main body 18). It has an air bleeding mechanism 24 having a shape in which a part is missing. Therefore, the filter jig 10 (second member 14) does not cover the entire surface of the liquid inflow port in the liquid receiving container 32 with the liquid receiving container 32 attached, and is a part of the inflow port of the liquid receiving container 32. Is open to the outside.
Therefore, since the portion opened by the air bleeding mechanism 24 acts as an air bleeder, filtration by gravity drop (self-weight drop) can be performed smoothly and quickly.

被処理液の濾過が終了したら、第１部材１２（または第２部材１４）のエア抜き機構２４側から、係合部３０の凹部に回収容器３４のフランジ３４ａを挿入させて、図８の右側に示すように、フィルター治具１０（治具本体１８）に、回収容器３４を装着する。 When the filtration of the liquid to be processed is completed, the flange 34a of the collection container 34 is inserted into the recess of the engaging portion 30 from the air bleeding mechanism 24 side of the first member 12 (or the second member 14), and the right side of FIG. As shown in the above, the collection container 34 is attached to the filter jig 10 (jig main body 18).

次いで、回収容器３４を下方にして、第２部材１４から液受け容器３２を取り外して、第２部材１４の貫通孔２０に回収液（洗浄液）を流入させ、回収液を濾過とは逆方向に流すことにより、フィルター１６によって濾別した、フィルター１６上の残渣を回収容器３４に回収する。
ここで、図３、図７および図８に示すように、第１部材１２も、外壁の一部を切り欠いた形状のエア抜き機構２４を有する。そのため、フィルター治具１０（第１部材１２）は、回収容器３４を装着された状態でも、回収容器３４における流入口の全面を覆わず、回収容器３４の流入口の一部が外部に開口した状態となる。
そのため、このエア抜き機構２４によって開口された部分が、エア抜きとして作用するので、回収液を重力落下させる残渣の回収も、円滑かつ迅速に濾過を行うことができる。 Next, with the recovery container 34 facing downward, the liquid receiving container 32 is removed from the second member 14, the recovery liquid (cleaning liquid) is allowed to flow into the through hole 20 of the second member 14, and the recovery liquid is flowed in the direction opposite to the filtration. By flowing, the residue on the filter 16 filtered by the filter 16 is collected in the collection container 34.
Here, as shown in FIGS. 3, 7, and 8, the first member 12 also has an air bleeding mechanism 24 having a shape in which a part of the outer wall is cut out. Therefore, the filter jig 10 (first member 12) does not cover the entire inflow port of the collection container 34 even when the collection container 34 is attached, and a part of the inflow port of the collection container 34 opens to the outside. It becomes a state.
Therefore, since the portion opened by the air bleeding mechanism 24 acts as an air bleeder, the recovery of the residue that causes the recovery liquid to drop by gravity can be smoothly and quickly filtered.

上述のように、本発明のフィルター治具１０およびサンプリング方法によれば、第１部材１２、すなわち、治具本体１８の貫通孔の一方の端部に液受け容器３２を装着して、被処理液の濾過を行い、次いで、第２部材１４、すなわち、治具本体１８の貫通孔の他方の端部に回収容器３４を装着して、濾過とは逆に回収液を流すことによって、フィルター１６で濾別した残渣を回収容器３４に回収する。
そのため、本発明によれば、濾過によって捕集した残渣を目的物とする濾過において、スパチュラ等によって残渣の回収を行う必要がないので、残渣の回収時に目的物を損傷することを防止できる。しかも、被処理液の濾過とは逆方向に回収液を流す逆洗のようにして残渣を回収できるので、フィルターを回収液に浸漬して残渣を回収する場合に比して、回収液の量を少なくできる。すなわち、本発明によれば、残渣を回収した回収液における目的物の濃度を高くでき、目的物の回収率も高くできる。 As described above, according to the filter jig 10 and the sampling method of the present invention, the liquid receiving container 32 is attached to one end of the through hole of the first member 12, that is, the jig body 18, and is to be treated. The filter 16 is filtered by filtering the liquid, and then the recovery container 34 is attached to the other end of the through hole of the second member 14, that is, the jig body 18, and the recovery liquid is flowed in the opposite direction to the filtration. The residue filtered by the above is collected in a collection container 34.
Therefore, according to the present invention, in the filtration using the residue collected by filtration as the target substance, it is not necessary to recover the residue with a spatula or the like, so that it is possible to prevent the target object from being damaged when the residue is recovered. Moreover, since the residue can be recovered by backwashing in which the recovery liquid is flowed in the direction opposite to the filtration of the liquid to be treated, the amount of the recovery liquid is compared with the case where the filter is immersed in the recovery liquid to recover the residue. Can be reduced. That is, according to the present invention, the concentration of the target product in the recovery liquid in which the residue is recovered can be increased, and the recovery rate of the target product can also be increased.

さらに、本発明のフィルター治具１０は、フィルター１６を挟んで接合される第１部材１２および第２部材１４の両方に、エア抜き機構２４を有する。すなわち、フィルター治具１０は、フィルター１６を挟むようにして、治具本体１８の貫通孔の両端部側に、エア抜き機構２４を有する。
そのため、被処理液の濾過を行う際にも、回収液によって残渣の回収を行う際にも、エア抜き機構２４によって、液受け容器３２および回収容器３４からのエア抜きを好適に行うことができ、重力による落下で、円滑かつ迅速な濾過および残渣の回収が可能になる。しかも、重力よる落下で濾過および残渣の回収を行うため、減圧（または加圧）等に起因して、残渣中の目的物が損傷することも防止できる。
加えて、フィルター治具１０自身（治具本体自身）が、貫通孔のフィルター１６の両側、すなわち、被処理液の濾過および残渣の回収の両方に対応してエア抜き機構を有するので、装着が可能であれば、液受け容器３２および回収容器３４の形状および種類等によらず、好適にエア抜きを行って、円滑かつ迅速な濾過および残渣の回収が可能である。 Further, the filter jig 10 of the present invention has an air bleeding mechanism 24 on both the first member 12 and the second member 14 which are joined with the filter 16 interposed therebetween. That is, the filter jig 10 has an air bleeding mechanism 24 on both ends of the through holes of the jig body 18 so as to sandwich the filter 16.
Therefore, the air bleeding mechanism 24 can suitably bleed air from the liquid receiving container 32 and the recovery container 34 both when filtering the liquid to be treated and when recovering the residue with the recovery liquid. Gravity drops allow for smooth and rapid filtration and residue recovery. Moreover, since filtration and recovery of the residue are performed by dropping due to gravity, it is possible to prevent damage to the target substance in the residue due to decompression (or pressurization) or the like.
In addition, since the filter jig 10 itself (the jig body itself) has an air bleeding mechanism corresponding to both sides of the filter 16 in the through hole, that is, both filtration of the liquid to be treated and recovery of the residue, mounting is possible. If possible, regardless of the shape and type of the liquid receiving container 32 and the recovery container 34, air can be appropriately bleeded to enable smooth and rapid filtration and recovery of the residue.

さらに、図示例のフィルター治具１０は、好ましい態様として、第１部材１２および第２部材１４すなわち治具本体１８の外壁の一部（外壁面の一部の形状）が、液受け容器３２および回収容器３４からエア抜きを行うためのエア抜き機構を構成する。図示例においては、第１部材１２および第２部材１４（治具本体１８）の外壁の一部を切り欠いた形状のエア抜き機構２４、すなわち、第１部材１２および第２部材１４を構成する壁の外側の一部を欠損した形状のエア抜き機構２４を有する。
言い換えれば、図示例のフィルター治具１０は、液受け容器３２および回収容器３４を装着した際に、フィルター治具１０が液受け容器３２および回収容器３４の流入口の全面を覆うことなく、容器の流入口の一部が外部に開口するように、外壁の一部に、外壁を切り欠いた（欠損した）ような形状のエア抜き機構２４を設けている。
このエア抜き機構２４は、第１部材１２および第２部材１４の貫通孔２０（治具本体の貫通孔）には連通していない。すなわち、エア抜き機構２４は、貫通孔２０における通液とは無関係であり、また、貫通孔２０は、エア抜きとは無関係である。
従って、治具本体１８の外壁の一部にエア抜き機構２４を有するフィルター治具１０によれば、濾過および残渣の回収の際に、エア抜きに起因して、被処理液および回収液がフィルター治具１０の外部に漏れることが無い。すなわち、本発明のフィルター治具１０においては、治具本体１８の外壁にエア抜き機構２４を設けることにより、エア抜き機構２４から、被処理液および回収液がフィルター治具１０の外部に漏れることが無い。 Further, in the filter jig 10 of the illustrated example, as a preferred embodiment, a part of the outer wall (a part of the shape of the outer wall surface) of the first member 12 and the second member 14, that is, the jig main body 18, is formed of the liquid receiving container 32 and the liquid receiving container 32. An air bleeding mechanism for bleeding air from the collection container 34 is configured. In the illustrated example, the air bleeding mechanism 24 having a shape in which a part of the outer wall of the first member 12 and the second member 14 (jig main body 18) is cut out, that is, the first member 12 and the second member 14 are configured. It has an air bleeding mechanism 24 having a shape in which a part of the outside of the wall is missing.
In other words, in the filter jig 10 of the illustrated example, when the liquid receiving container 32 and the collecting container 34 are attached, the filter jig 10 does not cover the entire inflow port of the liquid receiving container 32 and the collecting container 34. An air bleeding mechanism 24 having a shape such that the outer wall is cut out (missing) is provided in a part of the outer wall so that a part of the inflow port of the above can be opened to the outside.
The air bleeding mechanism 24 does not communicate with the through holes 20 (through holes of the jig body) of the first member 12 and the second member 14. That is, the air bleeding mechanism 24 is irrelevant to the liquid passing through the through hole 20, and the through hole 20 is irrelevant to the air bleeding.
Therefore, according to the filter jig 10 having the air bleeding mechanism 24 on a part of the outer wall of the jig main body 18, the liquid to be treated and the recovered liquid are filtered due to the air bleeding at the time of filtration and recovery of the residue. It does not leak to the outside of the jig 10. That is, in the filter jig 10 of the present invention, by providing the air bleeding mechanism 24 on the outer wall of the jig main body 18, the liquid to be treated and the recovered liquid leak to the outside of the filter jig 10 from the air bleeding mechanism 24. There is no.

また、図示例のフィルター治具１０は、好ましい態様として、貫通孔２０の貫通方向から見た際に、治具本体１８の貫通孔を挟んで対向するように、エア抜き機構２４を設けている。
このような構成を有するフィルター治具１０は、質量バランス、特に、治具本体１８の貫通孔の方向に対して直交する方向の質量バランスを良好にできるので、被処理液の濾過中および残渣の回収中に、フィルター治具１０が不要に倒れる等を防止できる。 Further, as a preferred embodiment, the filter jig 10 of the illustrated example is provided with an air bleeding mechanism 24 so as to face the through hole of the jig body 18 when viewed from the through hole 20. ..
Since the filter jig 10 having such a configuration can improve the mass balance, particularly the mass balance in the direction orthogonal to the direction of the through hole of the jig main body 18, during filtration of the liquid to be treated and of the residue. It is possible to prevent the filter jig 10 from falling unnecessarily during collection.

さらに、図示例のフィルター治具１０は、好ましい態様として、フィルター治具１０への液受け容器３２および回収容器３４の装着を、エア抜き機構２４側から行うように、エア抜き機構２４および係合部３０が設けられる。すなわち、エア抜き機構２４の位置と、係合部３０への容器の挿入位置とが、貫通孔の周方向で一致している。
このような構成を有することにより、係合部３０による液受け容器３２および回収容器３４の保持を確実にできる、フィルター治具１０への容器の装着方向を容易に認識できる等の点で好ましい。 Further, the filter jig 10 of the illustrated example is preferably engaged with the air bleeding mechanism 24 so that the liquid receiving container 32 and the collecting container 34 are mounted on the filter jig 10 from the air bleeding mechanism 24 side. A portion 30 is provided. That is, the position of the air bleeding mechanism 24 and the position of inserting the container into the engaging portion 30 coincide with each other in the circumferential direction of the through hole.
Having such a configuration is preferable in that the liquid receiving container 32 and the collecting container 34 can be reliably held by the engaging portion 30, and the mounting direction of the container on the filter jig 10 can be easily recognized.

エア抜き機構２４の形状および大きさ等には、制限はない。
すなわち、エア抜き機構２４を構成する切り欠き（欠損部）の形状および大きさ等は、被処理液の量、ならびに、液受け容器３２および回収容器３４の流入口の大きさおよび形状等に応じて、容器の流入口に十分なエア抜きが行える面積の開口を設けられる形状および大きさを、適宜、設定すればよい。 There are no restrictions on the shape and size of the air bleeding mechanism 24.
That is, the shape and size of the notch (defective portion) constituting the air bleeding mechanism 24 depends on the amount of the liquid to be treated and the size and shape of the inflow port of the liquid receiving container 32 and the recovery container 34. Therefore, the shape and size of the inflow port of the container to be provided with an opening having an area capable of sufficiently bleeding air may be appropriately set.

なお、本発明のフィルター治具において、第１部材１２および第２部材１４（治具本体１８）の外壁に設けるエア抜き機構は、図示例のように、外壁の一部を切り欠いた形状に制限はされない。
一例として、治具本体の外壁に設けるエア抜き機構は、第１部材（第２部材）を貫通孔２０の貫通方向に見た図９に概念的に示すように、外壁の一部の形状を凹状にしてエア抜き機構３８を有することで、液受け容器３２および回収容器３４を本発明のフィルター治具に装着した際に、容器の流入口の一部を開口した状態として、エア抜きを行うようにしてもよい。また、例えば、第１部材１２には、切り欠き状のエア抜き機構２４を設け、第２部材１４には凹状のエア抜き機構３８を設けた構成でもよい。
すなわち、本発明のフィルター治具において、第１部材１２および第２部材１４（治具本体１８）の外壁に設けるエア抜き機構は、治具本体１８の外観形状の連続性を失わせるように、外壁面が貫通孔に近接する形状を有するものであれば、各種の構成および形状のものが利用可能である。 In the filter jig of the present invention, the air bleeding mechanism provided on the outer walls of the first member 12 and the second member 14 (jig main body 18) has a shape in which a part of the outer wall is cut out as shown in the illustrated example. There are no restrictions.
As an example, the air bleeding mechanism provided on the outer wall of the jig body has a shape of a part of the outer wall as conceptually shown in FIG. 9 when the first member (second member) is viewed in the penetrating direction of the through hole 20. By having the air bleeding mechanism 38 in a concave shape, when the liquid receiving container 32 and the collecting container 34 are attached to the filter jig of the present invention, the air is bleeding with a part of the inflow port of the container opened. You may do so. Further, for example, the first member 12 may be provided with a notch-shaped air bleeding mechanism 24, and the second member 14 may be provided with a concave air bleeding mechanism 38.
That is, in the filter jig of the present invention, the air bleeding mechanism provided on the outer wall of the first member 12 and the second member 14 (jig body 18) is such that the continuity of the appearance shape of the jig body 18 is lost. Various configurations and shapes can be used as long as the outer wall surface has a shape close to the through hole.

図示例のフィルター治具１０において、第１部材１２および第２部材１４は、共に、エア抜き機構２４を、１個、有するものであるが、本発明は、これに制限はされない。
第１部材１２および第２部材１４は、少なくとも一方が、外壁に複数のエア抜き機構２４を有してもよい。すなわち、本発明のフィルター治具は、治具本体が、フィルター１６よりも貫通孔の端部側の少なくとも一方において、複数のエア抜き機構２４を有してもよい。この際において、各容器（フィルターに対して貫通孔の両端部側）に形成されるエア抜き機構は、同じものでも、異なるものでもよい。 In the filter jig 10 of the illustrated example, the first member 12 and the second member 14 both have one air bleeding mechanism 24, but the present invention is not limited thereto.
At least one of the first member 12 and the second member 14 may have a plurality of air bleeding mechanisms 24 on the outer wall. That is, in the filter jig of the present invention, the jig main body may have a plurality of air bleeding mechanisms 24 on at least one of the ends of the through holes with respect to the filter 16. At this time, the air bleeding mechanism formed in each container (both ends of the through hole with respect to the filter) may be the same or different.

図示例のフィルター治具１０は、第１部材１２および第２部材１４（治具本体）の外壁の一部が、エア抜き機構を構成するものであるが、本発明は、これに制限はされず、各種のエア抜き機構が利用可能である。
一例として、図１０に概念的に示すフィルター治具４０のように、第１部材１２ａおよび第２部材１４ｂ（治具本体１８ａ）に、外面から貫通孔２０に到るエア抜きのための貫通孔４２を設けて、エア抜き機構を構成してもよい。
また、例えば、エア抜きのための貫通孔４２を有する第１部材１２ａと、外壁を切り欠いた形状のエア抜き機構２４を有する第２部材１４とを組み合わせて、本発明のフィルター治具を構成してもよい。 In the filter jig 10 of the illustrated example, a part of the outer wall of the first member 12 and the second member 14 (jig main body) constitutes an air bleeding mechanism, but the present invention is limited to this. However, various air bleeding mechanisms can be used.
As an example, like the filter jig 40 conceptually shown in FIG. 10, through holes for bleeding air from the outer surface to the through holes 20 in the first member 12a and the second member 14b (jig main body 18a). 42 may be provided to form an air bleeding mechanism.
Further, for example, the filter jig of the present invention is configured by combining a first member 12a having a through hole 42 for bleeding air and a second member 14 having an air bleeding mechanism 24 having a shape in which an outer wall is cut out. You may.

以上、本発明のフィルター治具およびサンプリング方法について詳細に説明したが、本発明は上述の例に限定はされず、本発明の要旨を逸脱しない範囲において、各種の改良や変更を行ってもよいのは、もちろんである。
例えば、図１〜図３に示すフィルター治具１０は、第１部材１２と第２部材１４とが同じものであったが、本発明は、これに制限はされず、例えば、第１部材と第２部材とで、形状が異なってもよく、あるいは、第１部材と第２部材とで、大きさが異なってもよい。 Although the filter jig and the sampling method of the present invention have been described in detail above, the present invention is not limited to the above-mentioned examples, and various improvements and changes may be made without departing from the gist of the present invention. Of course.
For example, in the filter jig 10 shown in FIGS. 1 to 3, the first member 12 and the second member 14 are the same, but the present invention is not limited to this, for example, with the first member. The shape of the second member may be different, or the size of the first member and the second member may be different.

各種の用途における、残渣が目的物を含む濾過に、好適に利用可能である。 It can be suitably used for filtration in which the residue contains an object in various applications.

１０，４０フィルター治具
１２，１２ａ第１部材
１４，１４ａ第２部材
１６フィルター
１８，１８ａ治具本体
２０，４２貫通孔
２４，３８エア抜き機構
２６フランジ部
３０係合部
３２液受け容器
３２ａ．３４ａフランジ
３４回収容器 10,40 Filter jig 12, 12a 1st member 14, 14a 2nd member 16 Filter 18, 18a Jig body 20, 42 Through hole 24, 38 Air bleeding mechanism 26 Flange part 30 Engagement part 32 Liquid receiving container 32a. 34a Flange 34 Recovery container

Claims

A cylindrical jig body having a through hole that serves as a flow path for the liquid to be treated,
A filter provided in the middle of the through hole of the jig body so as to divide the flow path of the liquid to be treated into a first flow path and a second flow path in the flow direction of the liquid to be treated.
An air bleeding mechanism provided on the first flow path side and the second flow path side of the jig body.
It has an engaging portion provided on both ends of the through hole of the jig body, which engages with a storage container for containing the liquid that has passed through the through hole, and holds the storage container.
The jig main body has flange portions having notches on both end portions of the through hole, and the engaging portions are provided on the flange portions.
A filter jig characterized in that the notch in the flange portion constitutes at least a part of the air bleeding mechanism, and the engaging portion also serves as a positioning means for the storage container.

The filter jig according to claim 1, wherein a part of the outer wall of the jig body constitutes at least one of the air bleeding mechanisms.

The filter jig according to claim 2, wherein a part of the outer wall of the jig body constitutes all the air bleeding mechanisms.

2. Or the filter jig according to 3.

The filter jig according to claim 4, wherein a part of the outer wall of the jig body constituting the air bleeding mechanism has a shape in which a part of the jig body is missing.

The filter jig according to any one of claims 1 to 5 , wherein the engaging portion engages with the outside of the storage container.

The filter jig according to any one of claims 1 to 6 , wherein the engaging portion has a recess that engages with the storage container.

The filter jig according to any one of claims 1 to 7 , wherein the engaging portion has one or more notches in the outer peripheral direction of the through hole of the jig body.

The filter jig according to any one of claims 1 to 8 , wherein the insertion position of the storage container into the engaging portion and the position of the air bleeding mechanism coincide with each other in the outer peripheral direction of the through hole. Ingredients.

The through hole of the jig body, at least one of in response to the end, has an enlarged diameter portion whose diameter increases toward the end portion from the filter, according to any one of claims 1-9 Filter jig.

When viewed from the penetration direction of the through hole of the jig body, and the air vent mechanism provided in the first flow path side, and the air vent mechanism provided in the second flow path side, said through The filter jig according to any one of claims 1 to 10 , which faces each other with a hole in between.

The sampling method using the filter jig according to any one of claims 1 to 11 , after passing the liquid to be treated through the through hole of the jig main body.
A sampling method in which a residue on a filter is recovered by passing a recovery liquid through the through hole of the jig body in a direction opposite to the flow direction of the liquid to be treated.

With one end of the through hole of the jig body facing up and the other end facing down, at least one of the liquid to be treated and the liquid to be recovered is passed by dropping. The sampling method according to claim 12.