JP6842127B2 - 細胞毒性剤と細胞結合受容体との共役体 - Google Patents
細胞毒性剤と細胞結合受容体との共役体 Download PDFInfo
- Publication number
- JP6842127B2 JP6842127B2 JP2019095746A JP2019095746A JP6842127B2 JP 6842127 B2 JP6842127 B2 JP 6842127B2 JP 2019095746 A JP2019095746 A JP 2019095746A JP 2019095746 A JP2019095746 A JP 2019095746A JP 6842127 B2 JP6842127 B2 JP 6842127B2
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- alkyl
- heteroalkyl
- cycloalkyl
- mmol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019095746A JP6842127B2 (ja) | 2019-05-22 | 2019-05-22 | 細胞毒性剤と細胞結合受容体との共役体 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019095746A JP6842127B2 (ja) | 2019-05-22 | 2019-05-22 | 細胞毒性剤と細胞結合受容体との共役体 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017057224A Division JP6585650B2 (ja) | 2017-03-23 | 2017-03-23 | 細胞毒性剤と細胞結合受容体との共役体 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021016477A Division JP7044419B2 (ja) | 2021-02-04 | 2021-02-04 | 細胞毒性剤と細胞結合受容体との共役体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019167359A JP2019167359A (ja) | 2019-10-03 |
| JP2019167359A5 JP2019167359A5 (enExample) | 2020-02-06 |
| JP6842127B2 true JP6842127B2 (ja) | 2021-03-17 |
Family
ID=68106227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019095746A Active JP6842127B2 (ja) | 2019-05-22 | 2019-05-22 | 細胞毒性剤と細胞結合受容体との共役体 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP6842127B2 (enExample) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101678124A (zh) * | 2007-03-14 | 2010-03-24 | 恩多塞特公司 | 结合配体连接的微管溶素递药缀合物 |
| US8394922B2 (en) * | 2009-08-03 | 2013-03-12 | Medarex, Inc. | Antiproliferative compounds, conjugates thereof, methods therefor, and uses thereof |
-
2019
- 2019-05-22 JP JP2019095746A patent/JP6842127B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2019167359A (ja) | 2019-10-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6117921B2 (ja) | 細胞毒性剤と細胞結合受容体との共役体 | |
| JP6817288B2 (ja) | 新規な連結体及び生体分子と薬物との特異的共役におけるその使用 | |
| JP6759326B2 (ja) | 細胞結合分子の共役のための架橋連結体 | |
| JP6700321B2 (ja) | 細胞結合分子の特異的共役体 | |
| CN105641707B (zh) | 细胞毒素分子同细胞结合受体分子的共轭体 | |
| CN108026123A (zh) | 用于偶联的亲水链接体 | |
| JP7149610B2 (ja) | 細胞結合分子の特異的共役体 | |
| JP2021006531A (ja) | 細胞結合分子の共役のための架橋連結体 | |
| JP6585650B2 (ja) | 細胞毒性剤と細胞結合受容体との共役体 | |
| JP7774882B2 (ja) | 新規な連結体及び生体分子と薬物との特異的共役におけるその使用 | |
| JP7044419B2 (ja) | 細胞毒性剤と細胞結合受容体との共役体 | |
| JP6842127B2 (ja) | 細胞毒性剤と細胞結合受容体との共役体 | |
| HK1258097A1 (en) | Conjugates of cell binding molecules with cytotoxic agents | |
| NZ719369A (en) | Conjugates of cell binding molecules with cytotoxic agents | |
| NZ719369B2 (en) | Conjugates of Cell Binding Molecules with Cytotoxic Agents | |
| HK1210059B (en) | Conjugates of cell binding molecules with cytotoxic agents |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20190621 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20191219 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20200407 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20200707 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20200716 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20210105 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20210204 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6842127 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |