JP6806493B2 - Biopsy system and its operation method - Google Patents

Description

The present invention relates to a biomedical examination system for inspecting a subject using a device having a sensor for acquiring a biological signal from the subject and a terminal device capable of communicating with the device, and an operation method thereof .

There is known a biological examination system that acquires a biological signal from a subject and inspects the subject by an electrocardiogram, an electroencephalogram, an electromyogram, or the like (see, for example, Patent Documents 1 to 3 below). In such a biomedical examination system, a device having a sensor for acquiring a biological signal from a subject and a terminal device that performs data processing based on the biological signal acquired by the device are separated. Some have the provided configuration.

In this case, the biological signal acquired by the sensor is transmitted from the device to the terminal device via wired or wireless communication. Even when the amount of data transmitted from the device to the terminal device is large, if a terminal device having high data processing capability such as a desktop personal computer is used, the data received from the device is processed by the terminal device, and the subject's The test result can be obtained.

International Publication No. 2014/039646 Japanese Unexamined Patent Publication No. 2013-78543 Japanese Unexamined Patent Publication No. 2013-66719

In recent years, with the spread of mobile terminals such as smartphones, tablets, and mobile personal computers, a system has been proposed in which data is received from a device by these mobile terminals and the data is processed by a data processing unit provided in the mobile terminal. There is. However, since the above-mentioned mobile terminal generally has a lower data processing capacity than a desktop personal computer, the load at the time of data processing becomes very large. In particular, when a large amount of data (so-called big data) is collected at one time, the data processing capacity of the mobile terminal may be insufficient.

Since mobile terminals use battery power, it is very important to secure power. For example, in an emergency (disaster, etc.), the battery may not be charged, so processing of data from the device may interfere with the original functions of the mobile terminal such as calling, collecting and transmitting data. Therefore, it is preferable to reduce the load of data processing on the mobile terminal that receives data from the device. This is the same when not only a mobile terminal but also another terminal device having a low data processing capacity is used.

The present invention has been made in view of the above circumstances, and an object of the present invention is to provide a biopsy system and a biopsy method capable of reducing the burden of data processing in a terminal device that receives data from a device.

(1) The biopsy system according to the present invention includes a device and a terminal device. The device includes a sensor that acquires a biological signal from a subject, and a first data processing unit that processes data based on the biological signal input from the sensor. The terminal device has a second data processing unit that can communicate with the device and processes data received from the device, and a storage unit that stores data of reference frequency characteristics as comparative data.

The first data processing unit includes a basic data acquisition unit, a conversion processing unit, an inverse conversion processing unit, a first determination processing unit, and a transmission processing unit. The basic data acquisition unit acquires basic data representing the relationship between time and signal strength based on a biological signal input from the sensor. The transform processing unit generates transform data by performing a fast Fourier transform on the basic data. The inverse transform processing unit generates inverse transform data by performing an inverse fast Fourier transform on the transform data. The first determination processing unit determines an abnormality of the subject based on the basic data and the inverse conversion data. The transmission processing unit transmits the conversion data to the terminal device when the first determination processing unit determines that the abnormality is abnormal. The second data processing unit includes a second determination processing unit. The second determination processing unit determines the abnormality of the subject by comparing the conversion data received from the device with the comparison data.

(2) The biopsy method according to the present invention is a biopsy method for inspecting a subject using a device having a sensor that acquires a biosignal from the subject and a terminal device capable of communicating with the device. The basic data acquisition step, the conversion processing step, the inverse conversion processing step, the first determination processing step, the transmission processing step, and the second determination processing step are included.

In the basic data acquisition step, the device acquires basic data representing the relationship between time and signal strength based on a biological signal input from the sensor. In the conversion processing step, the device generates conversion data by performing a fast Fourier transform on the basic data. In the inverse transform processing step, the device generates inverse transform data by performing an inverse fast Fourier transform on the transform data. In the first determination processing step, the device determines an abnormality of the subject based on the basic data and the inverse conversion data. In the transmission processing step, when the device is determined to be abnormal by the first determination processing step, the conversion data is transmitted to the terminal device. In the second determination processing step, the terminal device determines the abnormality of the subject by comparing the conversion data received from the device with the comparison data which is the data of the reference frequency characteristic.

According to the present invention, basic data is acquired in the device based on the biological signal from the subject acquired by the sensor of the device, and fast Fourier transform and inverse fast Fourier transform are performed in the device with respect to the basic data. The device also makes an abnormality determination of the subject based on the obtained inverse transform data and the basic data. When the device is determined to be abnormal, the terminal device receives the converted data from the device and compares the converted data with the comparison data to determine the abnormality of the subject. In this way, the data processing based on the biological signal from the subject is distributed between the device side and the terminal device side, so that the burden of data processing in the terminal device that receives the data from the device can be reduced. ..

It is a block diagram which showed the structural example of the biopsy system which concerns on one Embodiment of this invention. It is a figure which showed an example of the waveform data of an electrocardiogram. It is a figure for demonstrating the difference value determination. It is a figure for demonstrating the histogram determination. It is a figure for demonstrating the comparison determination. It is a flowchart which showed an example of the processing by the 1st data processing part of a device. It is a flowchart which showed an example of the processing by the 2nd data processing part of a terminal apparatus.

1. 1. Configuration of Biopsy System FIG. 1 is a block diagram showing a configuration example of a biopsy system according to an embodiment of the present invention. This biopsy system is a system for inspecting an electrocardiogram, which is an example of biometric information of a subject, and is a terminal device 2 capable of communicating between a device 1 provided on the subject side and the device 1. And have. However, it is also possible to inspect not only the electrocardiogram of the subject but also other biological information such as electroencephalogram or electromyogram by the biopsy system according to the present invention.

The device 1 is composed of, for example, a wearable device worn by a subject. As the power source of the device 1, a primary battery, a secondary battery, a solar cell, or the like is used. The terminal device 2 is composed of a mobile terminal such as a smartphone, a tablet, or a mobile personal computer, and the subject can communicate with the device 1 while carrying it. That is, the device 1 is attached to the subject when the subject is living a daily life, and automatically transmits / receives data to / from the terminal device 2 carried by the subject. You can do it.

The device 1 includes a sensor 11, a first data processing unit 12, and a storage unit 13. The sensor 11 includes an electrode portion (not shown) for acquiring a biological signal such as a heartbeat from the subject. The electrode portion of the sensor 11 has an adhesive property that adheres to the body of the subject and a conductive property for detecting a biological signal as an electric signal. These characteristics can be compatible with each other, for example, by a configuration including a metal electrode and an adhesive material separated from each other, an adhesive material containing a conductive additive, and the like.

When the metal electrode and the adhesive material are provided separately, for example, an opening may be formed in the adhesive material to expose the metal electrode from the opening. The material of the metal electrode is not particularly limited as long as it is compatible with the human body, but for example, silver is preferably used. In this case, it is particularly preferable to use a silver paste in which silver particles having a particle size on the order of microns are dispersed in a resin. The material of the adhesive material is not particularly limited as long as it is compatible with the human body, but a resin material such as an acrylic resin or a silicon resin is preferably used. Acrylic resin is suitable for short-time application of, for example, several hours to one day, and silicone resin is suitable for longer-term application.

The biological signal detected by the metal electrode of the sensor 11 is input to the first data processing unit 12. At this time, the biological signal may be amplified by an amplifier (not shown) and input to the first data processing unit 12. The first data processing unit 12 has a configuration including, for example, a CPU (Central Processing Unit), and processes data based on a biological signal input from the sensor 11. The first data processing unit 12 functions as a basic data acquisition unit 121, a conversion processing unit 122, an inverse conversion processing unit 123, a first determination processing unit 124, a transmission processing unit 125, and the like when the CPU executes a program.

The basic data acquisition unit 121 acquires basic data representing a change over time in the intensity of the biological signal based on the biological signal input from the sensor 11. That is, the basic data represents the relationship between the signal strength of the biological signal and time. When an electrocardiogram is examined as biological information of a subject, the basic data is the waveform data of the electrocardiogram. The basic data acquired by the basic data acquisition unit 121 is stored in the storage unit 13. The storage unit 13 is composed of, for example, a RAM (Random Access Memory).

The transformation processing unit 122 performs a fast Fourier transform (FFT) on the basic data stored in the storage unit 13. By the processing of the conversion processing unit 122, conversion data representing the relationship between the frequency and the norm is generated. When the basic data is the waveform data of the electrocardiogram as shown in FIG. 2, the waves other than the R wave (P wave, Q wave, S wave, T wave, U wave, etc.) are detected as wide waves, but the frequency characteristics In the converted data converted into a value, it can be detected as a peak.

The inverse transform processing unit 123 performs an inverse fast Fourier transform (IFFT) on the transformed data. By the processing of the inverse conversion processing unit 123, the inverse conversion data representing the relationship between the signal strength and the time is generated again. In the present embodiment, the inverse fast Fourier transform is performed not on the entire transform data but on a part of the transform data. Specifically, the inverse fast Fourier transform is performed on the converted data whose frequency is equal to or less than a predetermined threshold value. Thereby, after removing the high frequency component which becomes a noise component from the conversion data, the inverse conversion data can be generated from the conversion data.

The first determination processing unit 124 determines an abnormality of the subject based on the basic data stored in the storage unit 13 and the inverse conversion data generated by the inverse conversion processing unit 123. Any method can be adopted as the method for determining the abnormality by the first determination processing unit 124, but in the present embodiment, the abnormality determination is performed using the difference value determination and the histogram determination. The specific method of the difference value determination and the histogram determination will be described later.

The transmission processing unit 125 transmits the conversion data generated by the conversion processing unit 122 to the terminal device 2 when the first determination processing unit 124 determines that there is an abnormality. For communication between the device 1 and the terminal device 2 by the transmission processing unit 125, it is preferable, but not limited to, wireless communication having low power consumption such as Bluetooth (registered trademark) is used. , Wired communication may be used.

The terminal device 2 includes a second data processing unit 21, a storage unit 22, and an input receiving unit 23. The second data processing unit 21 has a configuration including, for example, a CPU (Central Processing Unit), and processes data received from the device 1. The second data processing unit 21 functions as a reception processing unit 211, a second determination processing unit 212, a notification processing unit 213, and the like when the CPU executes a program.

The reception processing unit 211 performs a process of receiving data transmitted from the transmission processing unit 125 of the device 1. The second determination processing unit 212 determines the abnormality of the subject based on the data received by the reception processing unit 211. Any method can be adopted as the method for determining the abnormality by the second determination processing unit 212, but in the present embodiment, the conversion data received from the device 1 and the comparison data representing the healthy state of the subject are compared. A comparison determination is made to compare with. The specific method of comparison determination will be described later.

The comparison data is stored in advance in the storage unit 22. The storage unit 13 is composed of, for example, a ROM (Read Only Memory), a RAM (Random Access Memory), a hard disk, a memory card, or the like.

The input receiving unit 23 accepts the input of data by direct input or communication from the outside. When the input of the comparison data is received by the input receiving unit 23, the comparison data is stored in the storage unit 22. For example, when the comparison data is directly input to the input receiving unit 23 by operating the operation unit (not shown), the input comparison data is stored in the storage unit 22. Further, when comparison data is input from the outside to the input reception unit 23 by wired or wireless communication, the input comparison data is stored in the storage unit 22.

As a result, arbitrary comparison data can be stored in the storage unit 22, so that comparison determination can be performed using appropriate comparison data according to the subject. When the input reception unit 23 newly receives the input of the comparison data, the comparison data stored in the storage unit 22 may be updated by being overwritten with the new comparison data (update process). Process). In this case, it is possible to make a comparison judgment using more appropriate comparison data according to changes in the age and physical condition of the subject.

The notification processing unit 213 performs processing for notifying the final result of the abnormality determination of the subject. The processing by the notification processing unit 213 is performed by various processes such as a process of displaying the determination result on a display unit (not shown) provided in the terminal device 2 or a process of notifying the determination result by voice or the like. It can be carried out.

2. 2. Difference value determination FIG. 3 is a diagram for explaining the difference value determination. The difference value determination performed by the first determination processing unit 124 of the device 1 is performed by comparing the peak included in the waveform W11 of the basic data with the peak included in the waveform W12 of the inverse conversion data. The basic data is the data before the fast Fourier transform is performed, while the inverse transform data is the data obtained by performing the fast Fourier transform on the basic data and further performing the inverse fast Fourier transform. Therefore, as shown in FIG. 3, the variation that occurs in the biological signal of the subject appears as a deviation of the waveforms W11 and W12.

Specifically, the difference value A between the signal strength of the specific peak P11 (height of the peak apex) in the basic data and the signal strength of the corresponding peak P12 (height of the peak apex) in the inverse conversion data is the subject. This is due to the variation in signal strength that occurs in the examiner's biological signal. When the basic data is the waveform data of the electrocardiogram, variations such as blood pressure or blood component amount (blood resistivity) appear as the difference value A.

Therefore, based on the difference value A, it is possible to determine the abnormality of the subject regarding blood pressure, blood component amount, and the like. In this case, if the difference value A is equal to or greater than a predetermined threshold value, it may be determined to be abnormal. In this example, the difference value A of the signal intensities of the peaks corresponding to the R waves of the electrocardiogram is calculated as the specific peaks P11 and P12, but the difference values of the signal intensities of other peaks may be calculated.

Further, the difference value B between the detection time of the specific peak P21 in the basic data (time of the peak apex) and the detection time of the corresponding peak P22 in the inverse conversion data (time of the peak apex) is the biological signal of the subject. This is due to the variation in time that occurs in. When the basic data is the waveform data of the electrocardiogram, the variation such as the heartbeat appears as the difference value B.

Therefore, it is possible to determine the abnormality of the subject regarding the heartbeat and the like based on the difference value B. In this case, if the difference value B is equal to or greater than a predetermined threshold value, it may be determined to be abnormal. In this example, the difference value B of the detection time of the peak corresponding to the T wave of the electrocardiogram is calculated as the specific peaks P21 and P22, but the difference value of the detection time of other peaks may be calculated.

3. 3. Histogram determination FIG. 4 is a diagram for explaining the histogram determination. In the histogram determination performed by the first determination processing unit 124 of the device 1, the signal strength is divided into a plurality of divisions, and the number of times the signal strength of each division is detected is used as the detection frequency for each signal strength in the basic data (for each division). ) Is calculated, and the histogram data indicating the detection frequency for each signal strength (for each division) in the inverse conversion data is calculated. Then, by comparing the histogram data, the abnormality of the subject is determined.

Specifically, as shown in FIG. 4, the intersection D of the detection frequency D1 of the basic data in a certain signal strength category and the detection frequency D2 of the inverse conversion data in the same signal strength category is plotted. By plotting such intersections D for all signal strength divisions, the detection frequencies for each signal strength (for each division) in each histogram data of the basic data and the inverse conversion data are associated with each other. If the basic data and the inverse conversion data are the same data, the points plotted in this way will be distributed on the same straight line L1.

However, as shown in FIG. 4, each plotted point may be separated from the straight line L1 due to the variation in the biological signal of the subject. Based on the variation of such histogram data, it is possible to determine blood pressure, blood component amount, heartbeat, and other abnormalities of the subject.

In this example, the detection frequency of the basic data and the detection frequency of the inverse conversion data are compared for each signal strength by comparing the detection frequencies for each signal strength (for each division) in each histogram data of the basic data and the inverse conversion data. (For example, D2 / D1) is calculated as a comparison reference value. Then, the abnormality of the subject is determined based on whether or not the comparison reference value is within a predetermined threshold range. The threshold range is, for example, a range between the lower limit of distribution represented by the straight line L1 and the upper limit of distribution represented by the straight line L2.

However, the comparison reference value is not limited to the ratio of the detection frequency of the basic data and the detection frequency of the inverse conversion data, and may be another value. For example, the slope of the straight line connecting each point plotted for each signal strength and the origin is calculated as a comparison reference value, and the subject's abnormality is based on whether or not the comparison reference value is within a predetermined threshold range. May be determined.

The histogram determination process may be performed in the same process as the difference value determination process, or may be performed in separate processes. Since the basic data acquisition unit 121 continuously acquires basic data based on the biological signal input from the sensor 11, each process of histogram determination and difference value determination is performed from the viewpoint of preventing delay in processing. Is preferably done in a separate process.

4. Comparison determination FIG. 5 is a diagram for explaining the comparison determination. The comparison determination performed by the second determination processing unit 212 of the terminal device 2 is performed by comparing the waveform W21 of the conversion data received from the device 1 with the waveform W22 of the comparison data stored in the storage unit 22. .. The comparative data is, for example, data of a subject in a healthy state, that is, data obtained by measuring the subject in a healthy state. However, the comparison data is not limited to the data acquired from the subject, and may be, for example, data of a reference healthy person, that is, data obtained by measuring a general healthy person.

In the healthy waveform W22, a peak appears at a frequency corresponding to the characteristic of the change over time of the biological signal. Specifically, in each of the waveforms W21 and W22, the peak appearing at frequency F1 is the interval between adjacent R waves (RR interval), and the peak appearing at frequency F2 is the interval between adjacent Q waves (QT interval) and frequency. The peak that appears at F3 is the width of the T wave (T wave width), the peak that appears at frequency F4 is the interval between adjacent S and T waves (ST interval), and the peak that appears at frequency F5 is the interval between adjacent P and Q waves ( The peaks appearing at frequency F6 (PQ interval) correspond to the intervals between adjacent Q and S waves (QRS interval), respectively.

In the comparison determination, parameters such as the position (frequency), height or half width of peaks appearing in the waveforms W21 and W22 at specific frequencies F1 to F6 as described above are compared. The full width at half maximum means the width at half the height of the peak. In this case, if the difference between the above parameters in the waveforms W21 and W22 is equal to or greater than a predetermined threshold value, it may be determined to be abnormal. It is also possible to determine a specific symptom of abnormality depending on whether the difference between the above parameters is equal to or greater than a predetermined threshold value at which frequency of the frequencies F1 to F6 appears.

5. Processing in the device FIG. 6 is a flowchart showing an example of processing by the first data processing unit 12 of the device 1. In the device 1, basic data is continuously acquired based on the biological signal input from the sensor 11 (step S101: basic data acquisition step). Then, the transformed data is generated by performing the fast Fourier transform on the acquired basic data (step S102: conversion processing step), and the inverse fast Fourier transform is performed on the generated transformed data. The conversion data is generated (step S103: inverse transform processing step).

Of the basic data, the conversion data, and the reverse conversion data thus obtained, the abnormality of the subject is determined in the device 1 based on the basic data and the reverse conversion data (step S104: first determination processing step). ). In the abnormality determination in the device 1, the general symptom of the subject is determined by mathematical data analysis such as the above-mentioned difference value determination or histogram determination. Since the device 1 may be used by an unspecified number of subjects, in the first determination processing step, a general abnormality determination is performed instead of an individual abnormality determination for a specific subject. It has become.

If an abnormality is determined by the first determination processing step (Yes in step S105), the conversion data generated at the time of the determination is transmitted to the terminal device 2 (step S106: transmission processing step). In this way, conversion data that is data other than the data (basic data and inverse conversion data) used in the first determination processing step in the device 1 is transmitted to the terminal device 2, and the conversion data is used in the terminal device 2. The processing that was done is performed.

6. Processing in the terminal device FIG. 7 is a flowchart showing an example of processing by the second data processing unit 21 of the terminal device 2. The terminal device 2 monitors whether or not the converted data is received from the device 1 (step S201). Since the terminal device 2 is carried by the subject, the conversion data is automatically received by the terminal device 2 each time the device 1 detects an abnormality of the subject and the conversion data is transmitted. It has become like.

When the terminal device 2 receives the converted data from the device 1 (Yes in step S201), the terminal device 2 performs an abnormality determination of the subject. Specifically, the comparison data is read from the storage unit 22 (step S202), and the abnormality of the subject is determined based on the comparison data and the conversion data received from the device 1 (step S203: Second determination processing step).

In the abnormality determination in the terminal device 2, the individual symptom of the subject is determined using the data of the subject's normal condition or the data of the reference healthy subject as in the above-mentioned comparison determination. To. That is, it is not a general symptom such as the abnormality determination performed by the device 1, but an individual abnormality determination is performed by comparison with the reference frequency characteristic data.

Since the terminal device 2 is not used by an unspecified number of subjects like the device 1 but is individually owned by each subject, it is individual for a specific subject. Suitable for making anomaly judgment. In this way, the data processing based on the biological signal from the subject is distributed between the device 1 side and the terminal device 2 side, thereby reducing the burden of data processing in the terminal device 2 that receives the data from the device 1. can do.

If, as a result of the abnormality determination in the terminal device 2, it is determined that the subject has an abnormality (Yes in step S204), that fact (incorrectity) is notified to the subject via the terminal device 2. (Step S205: Notification processing step). The device 1 is worn on the subject on a daily basis, and when an abnormality of the subject is detected in the device 1, the converted data is transmitted to the terminal device 2 at any time, so that the subject has an abnormality. At that time, the terminal device 2 can be notified in real time.

On the other hand, when it is determined that the subject has no abnormality (No in step S204), the comparison data is updated with the conversion data used for the determination (step S206: update processing step). That is, since the converted data when it is determined that the subject has no abnormality is the latest data as the normal data of the subject, the converted data is overwritten in the storage unit 22 as comparison data. , Subsequent comparison judgment can be optimized.

7. Modifications In the above embodiments, the biopsy system including the device 1 and the terminal device 2 has been described, but the device 1 or the terminal device 2 included in the biopsy system may be individually provided, or the device 1 or the terminal device 2 may be provided individually. It is also possible to individually provide programs executed by such computers. In this case, the program may be provided in a state of being stored in a storage medium, or the program itself may be provided by wire or wirelessly.

(1) The biopsy system according to the present invention acquires basic data representing the relationship between time and signal strength based on a sensor that acquires a biometric signal from a subject and a biometric signal input from the sensor. A basic data acquisition unit, a conversion processing unit that generates conversion data by performing a high-speed Fourier transform on the basic data, and a conversion processing unit that generates inverse conversion data by performing an inverse fast Fourier transform on the conversion data. Calculates the difference value between the inverse transform processing unit, the signal strength of a specific peak in the basic data, and the signal strength of the corresponding peak in the inverse transform data, and determines the abnormality of the subject based on the difference value. It may be provided with a determination processing unit for determination.

(2) The biopsy system according to the present invention acquires basic data representing the relationship between time and signal strength based on a sensor that acquires a biometric signal from a subject and a biometric signal input from the sensor. A basic data acquisition unit, a conversion processing unit that generates conversion data by performing a high-speed Fourier transform on the basic data, and a conversion processing unit that generates inverse conversion data by performing an inverse fast Fourier transform on the conversion data. The difference value between the inverse transform processing unit, the detection time of a specific peak in the basic data, and the detection time of the corresponding peak in the inverse transform data is calculated, and the abnormality of the subject is determined based on the difference value. It may be provided with a determination processing unit for determination.

(3) The biopsy system according to the present invention acquires basic data representing the relationship between time and signal strength based on a sensor that acquires a biometric signal from a subject and a biometric signal input from the sensor. The basic data acquisition unit, the conversion processing unit that generates conversion data by performing high-speed Fourier conversion on the basic data, and the inverse conversion data by performing inverse high-speed Fourier conversion on the conversion data. The inverse conversion processing unit, the histogram data representing the detection frequency for each signal strength in the basic data, and the histogram data representing the detection frequency for each signal strength in the inverse conversion data are calculated, and the histogram data are compared. Therefore, it may be provided with a determination processing unit for determining an abnormality of the subject.

(4) The determination processing unit calculates a comparison reference value by comparing the detection frequencies for each signal strength in each of the calculated histogram data, and whether or not the comparison reference value is within a predetermined threshold range. The abnormality of the subject may be determined based on.

(5) The inverse transform processing unit may generate inverse transform data by performing inverse fast Fourier transform on the converted data whose frequency is equal to or less than a predetermined threshold value.

(6) The biopsy method according to the present invention is a biopsy method for inspecting a subject using a sensor that acquires a biometric signal from the subject, and is based on the biometric signal input from the sensor. The basic data acquisition step of acquiring the basic data representing the relationship between time and signal strength, the conversion processing step of generating the conversion data by performing the fast Fourier transform on the basic data, and the conversion data On the other hand, the difference value between the inverse transform processing step of generating inverse transform data by performing the inverse fast Fourier transform, the signal strength of a specific peak in the basic data, and the signal strength of the corresponding peak in the inverse transform data. May be provided with a determination processing step of calculating the data and determining the abnormality of the subject based on the difference value.

(7) The biopsy method according to the present invention is a biopsy method for inspecting a subject using a sensor that acquires a biometric signal from the subject, and is based on the biometric signal input from the sensor. The basic data acquisition step of acquiring the basic data representing the relationship between time and signal strength, the conversion processing step of generating the conversion data by performing the fast Fourier transform on the basic data, and the conversion data On the other hand, the difference value between the inverse transform processing step of generating inverse transform data by performing the inverse fast Fourier transform, the detection time of a specific peak in the basic data, and the detection time of the corresponding peak in the inverse transform data. May be provided with a determination processing step of calculating the data and determining the abnormality of the subject based on the difference value.

(8) The biopsy method according to the present invention is a biopsy method for inspecting a subject using a sensor that acquires a biometric signal from the subject, and is based on the biometric signal input from the sensor. The basic data acquisition step of acquiring the basic data representing the relationship between time and signal strength, the conversion processing step of generating conversion data by performing high-speed Fourier conversion on the basic data, and the conversion data On the other hand, the inverse conversion processing step of generating the inverse conversion data by performing the inverse high-speed Fourier transformation, the histogram data showing the detection frequency for each signal strength in the basic data, and the detection frequency for each signal strength in the inverse conversion data. It may be provided with a determination processing step of determining an abnormality of the subject by calculating the histogram data representing the above and comparing the histogram data.

(9) In the determination processing step, a comparison reference value is calculated by comparing the detection frequencies for each signal strength in each of the calculated histogram data, and whether or not the comparison reference value is within a predetermined threshold range. The abnormality of the subject may be determined based on.

(10) In the inverse transform processing step, the inverse transform data may be generated by performing the inverse fast Fourier transform on the data whose frequency is equal to or less than a predetermined threshold value among the converted data.

1 Device 2 Terminal device 11 Sensor 12 1st data processing unit 13 Storage unit 21 2nd data processing unit 22 Storage unit 23 Input reception unit 121 Basic data acquisition unit 122 Conversion processing unit 123 Inverse conversion processing unit 124 Judgment processing unit 125 Transmission processing Unit 211 Reception processing unit 212 Judgment processing unit 213 Notification processing unit

Claims (20)

A device having a sensor that acquires a biological signal from a subject and a first data processing unit that processes data based on the biological signal input from the sensor.
It is provided with a terminal device capable of communicating with the device and having a second data processing unit that processes data received from the device and a storage unit that stores data of reference frequency characteristics as comparison data.
The first data processing unit
A basic data acquisition unit that acquires basic data representing the relationship between time and signal strength based on a biological signal input from the sensor.
A conversion processing unit that generates conversion data by performing a fast Fourier transform on the basic data,
An inverse transform processing unit that generates inverse transform data by performing inverse fast Fourier transform on the transformed data,
A first determination processing unit that determines an abnormality of a subject based on the basic data and the inverse conversion data, and
Includes a transmission processing unit that transmits the converted data to the terminal device when it is determined to be abnormal by the first determination processing unit.
The second data processing unit
A biopsy system including a second determination processing unit that determines an abnormality of a subject by comparing the conversion data received from the device with the comparison data. The living body according to claim 1, wherein the inverse transform processing unit generates inverse transform data by performing inverse fast Fourier transform on data having a frequency equal to or lower than a predetermined threshold value among the converted data. Inspection system. The first determination processing unit calculates a difference value between the signal strength of a specific peak in the basic data and the signal strength of the corresponding peak in the inverse conversion data, and the abnormality of the subject is based on the difference value. The biopsy system according to claim 1 or 2, wherein the determination is made. The first determination processing unit calculates a difference value between the detection time of a specific peak in the basic data and the detection time of the corresponding peak in the inverse conversion data, and the abnormality of the subject is based on the difference value. The biopsy system according to any one of claims 1 to 3, wherein the biopsy system is characterized in that. The first determination processing unit calculates histogram data representing the detection frequency for each signal strength in the basic data and histogram data representing the detection frequency for each signal strength in the inverse conversion data, and compares the histogram data. The biopsy system according to any one of claims 1 to 4, wherein the abnormality of the subject is determined by the operation. The first determination processing unit calculates a comparison reference value by comparing the detection frequencies for each signal strength in each of the calculated histogram data, and determines whether or not the comparison reference value is within a predetermined threshold range. The biopsy system according to claim 5, wherein the abnormality of the subject is determined based on the above. The biopsy system according to any one of claims 1 to 6, wherein the device is a wearable device worn by a subject. The terminal device has an input receiving unit that accepts input of data by direct input or communication from the outside, and is characterized in that comparison data for which input is received by the input receiving unit is stored in the storage unit. The biopsy system according to any one of claims 1 to 7. The biopsy system according to claim 8, wherein the comparison data stored in the storage unit is updated when the input of the comparison data is newly received by the input reception unit. The biopsy system according to any one of claims 1 to 9, wherein the comparison data is data of a healthy subject or data of a reference healthy subject. A biomedical examination system including a device having a sensor for acquiring a biological signal from a subject and a terminal device capable of communicating with the device is an operation method of the biomedical examination system for inspecting a subject.
A basic data acquisition step in which the device acquires basic data representing the relationship between time and signal strength based on a biological signal input from the sensor.
A conversion processing step in which the device generates transformation data by performing a fast Fourier transform on the basic data.
An inverse transform processing step in which the device generates inverse transform data by performing an inverse fast Fourier transform on the transform data.
A first determination processing step in which the device determines an abnormality of the subject based on the basic data and the inverse conversion data.
A transmission processing step of transmitting the conversion data to the terminal device when the device is determined to be abnormal by the first determination processing step.
The terminal device includes a second determination processing step of determining an abnormality of the subject by comparing the conversion data received from the device with comparison data which is data of a reference frequency characteristic. A characteristic method of operating a biopsy system . The living body according to claim 11, wherein in the inverse transform processing step, inverse transform data is generated by performing inverse fast Fourier transform on data having a frequency equal to or lower than a predetermined threshold value among the converted data. How to operate the inspection system . In the first determination processing step, a difference value between the signal strength of a specific peak in the basic data and the signal strength of the corresponding peak in the inverse conversion data is calculated, and the abnormality of the subject is calculated based on the difference value. The method of operating the biopsy system according to claim 11 or 12, wherein the method of operating the biopsy system . In the first determination processing step, a difference value between the detection time of a specific peak in the basic data and the detection time of the corresponding peak in the inverse conversion data is calculated, and the abnormality of the subject is calculated based on the difference value. The method for operating a biopsy system according to any one of claims 11 to 13, wherein the method of operating the biopsy system is characterized by determining. In the first determination processing step, histogram data representing the detection frequency for each signal strength in the basic data and histogram data representing the detection frequency for each signal strength in the inverse conversion data are calculated, and the histogram data are compared. The method for operating a biopsy system according to any one of claims 11 to 14, wherein the abnormality of the subject is determined by the operation . In the first determination processing step, a comparison reference value is calculated by comparing the detection frequencies for each signal strength in each of the calculated histogram data, and whether or not the comparison reference value is within a predetermined threshold range is determined. The method of operating a biopsy system according to claim 15, wherein an abnormality of a subject is determined based on the method . The method for operating a biopsy system according to any one of claims 11 to 16, wherein the device is a wearable device worn by a subject. The terminal device is characterized by having an input receiving unit that receives input of data by direct input or communication from the outside, and a storage unit that stores comparison data for which input is received by the input receiving unit. The method for operating a biopsy system according to any one of 11 to 17. The biopsy according to claim 18, further comprising an update processing step of updating the comparison data stored in the storage unit when a new input of comparison data is received in the input reception unit. How the system works . The method for operating a biopsy system according to any one of claims 11 to 19, wherein the comparison data is data on a healthy subject or data on a reference healthy subject.

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