JP6707081B2 - 正の選択下で遺伝子を同定する方法 - Google Patents

正の選択下で遺伝子を同定する方法 Download PDF

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JP6707081B2
JP6707081B2 JP2017522100A JP2017522100A JP6707081B2 JP 6707081 B2 JP6707081 B2 JP 6707081B2 JP 2017522100 A JP2017522100 A JP 2017522100A JP 2017522100 A JP2017522100 A JP 2017522100A JP 6707081 B2 JP6707081 B2 JP 6707081B2
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mutations
distribution
scores
gene
genes
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JP2017537380A (ja
JP2017537380A5 (cg-RX-API-DMAC10.html
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リチタージ・オリビエ
スー・テン−クウェイ
カトソニス・パナジオティス
コワル・アマンダ・ミシェル
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Baylor College of Medicine
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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B10/00—ICT specially adapted for evolutionary bioinformatics, e.g. phylogenetic tree construction or analysis
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10—Complex mathematical operations
    • G06F17/11—Complex mathematical operations for solving equations, e.g. nonlinear equations, general mathematical optimization problems
    • G06F17/13—Differential equations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/60—In silico combinatorial chemistry
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/40—Population genetics; Linkage disequilibrium

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  • Life Sciences & Earth Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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JP2017522100A 2014-10-22 2015-10-21 正の選択下で遺伝子を同定する方法 Expired - Fee Related JP6707081B2 (ja)

Applications Claiming Priority (3)

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US201462067294P 2014-10-22 2014-10-22
US62/067,294 2014-10-22
PCT/US2015/056646 WO2016064995A1 (en) 2014-10-22 2015-10-21 Method to identify genes under positive selection

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JP2017537380A JP2017537380A (ja) 2017-12-14
JP2017537380A5 JP2017537380A5 (cg-RX-API-DMAC10.html) 2018-11-29
JP6707081B2 true JP6707081B2 (ja) 2020-06-10

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US (1) US10886005B2 (cg-RX-API-DMAC10.html)
EP (1) EP3210141A1 (cg-RX-API-DMAC10.html)
JP (1) JP6707081B2 (cg-RX-API-DMAC10.html)
AU (1) AU2015336005B2 (cg-RX-API-DMAC10.html)
CA (1) CA2965163A1 (cg-RX-API-DMAC10.html)
WO (1) WO2016064995A1 (cg-RX-API-DMAC10.html)

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Publication number Priority date Publication date Assignee Title
WO2016064995A1 (en) 2014-10-22 2016-04-28 Baylor College Of Medicine Method to identify genes under positive selection
US10395759B2 (en) 2015-05-18 2019-08-27 Regeneron Pharmaceuticals, Inc. Methods and systems for copy number variant detection
JP6765433B2 (ja) 2016-02-12 2020-10-07 リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 異常な核型の検出のための方法
US11281977B2 (en) * 2017-07-31 2022-03-22 Cognizant Technology Solutions U.S. Corporation Training and control system for evolving solutions to data-intensive problems using epigenetic enabled individuals
CN110782947A (zh) * 2019-10-18 2020-02-11 湖南大学 基于蛋白质序列功能区域的癌症驱动识别
WO2021178952A1 (en) * 2020-03-06 2021-09-10 The Research Institute At Nationwide Children's Hospital Genome dashboard
CN113643754B (zh) * 2021-08-11 2023-12-29 苏州赛美科基因科技有限公司 一种错义变异基因的评分处理方法、优化评分方法及装置
CN116897723A (zh) * 2022-08-01 2023-10-20 中国农业科学院都市农业研究所 一种基于植物感光基因调节的光源排列系统及方法

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Publication number Priority date Publication date Assignee Title
EP2899660A1 (en) 1999-08-27 2015-07-29 Iris Biotechnologies Inc. Artificial intelligence system for genetic analysis
WO2003046153A2 (en) 2001-11-28 2003-06-05 Baylor College Of Medicine The use of quantitative evolutionary trace analysis to determine functional residues
KR101325736B1 (ko) * 2010-10-27 2013-11-08 삼성에스디에스 주식회사 바이오 마커 추출 장치 및 방법
WO2014007863A1 (en) 2012-07-03 2014-01-09 Baylor College Of Medicine Biological action of missense genotype perturbations on phenotype
WO2016064995A1 (en) 2014-10-22 2016-04-28 Baylor College Of Medicine Method to identify genes under positive selection

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CA2965163A1 (en) 2016-04-28
US20170316148A1 (en) 2017-11-02
JP2017537380A (ja) 2017-12-14
AU2015336005B2 (en) 2018-07-26
AU2015336005A1 (en) 2017-05-11
WO2016064995A1 (en) 2016-04-28
US10886005B2 (en) 2021-01-05
EP3210141A1 (en) 2017-08-30

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