JP6663880B2 - Glove sterilization support member and isolator - Google Patents

Description

  The present invention relates to a glove sterilization support member used for sterilizing a work chamber of an isolator or a surface of a glove, and an isolator using the same.

  An isolator is used when conducting research on a pathogen or the like or treating a tissue possibly infected with the pathogen or the like in regenerative medicine or the like. In the isolator, a worker can perform work from outside the work room through work gloves. For example, in regenerative medicine, the patient's tissue to be treated may be infected with an infectious disease.Before changing the patient's tissue to be treated, the work room should be Must be cleaned and disinfected to be sterile.

  In the research, pathogens are handled in the working room of the isolator. The pathogen refers to a virus, a bacterium, a fungus, or the like, each having a unique property, and the pathogen may affect another pathogen. When changing the type of pathogen or the like handled in the same isolator, it is necessary to clean, disinfect, and sterilize the gloves used in the work room and in the work. Sterilization is performed by supplying a sterilizing gas to a work room or a glove.

  If the work glove is not supported, the work glove hangs down and comes into contact with the surface of the work equipment in the work room or the wall of the work room, or the glove surface or each finger overlaps and comes into contact May be insufficiently sterilized.

  Patent Literature 1 is a document relating to an auxiliary tool for decontaminating (sterilizing) the entire surface of a work glove. Patent Literature 1 states that “a glove decontamination support includes an arm support member that is inserted into the arm of a working glove from the outside of the work chamber toward the wrist from the upper arm of the arm. A fixing member fixed to the opening of the port for stably holding the position of the arm supporting member, and a finger / palm supporting member for extending and supporting the palm of the working glove and each finger without contacting each other (Refer to the summary). "

JP-A-2006-77858

  As described in paragraphs 0061 and 0062 of the glove decontamination support of Patent Document 1, the arm of the working glove is placed inside the arm from the outside of the work chamber toward the wrist from the upper arm of the arm. By inserting, the arm extending member provided on the arm supporting member stably supports the arm of the working glove in a horizontal state without hanging down, and furthermore, the partition board provided at the tip slides. By the compressed air confined between the palm and each finger, the surfaces of the palm and each finger are maintained in an expanded state without contacting each other.

  However, if the air trapped between the palm and each finger of the glove cannot be compressed or the amount of compression is insufficient, the surfaces of the palm and each finger contact each other. Is too large, the flexible glove spreads out and does not consider contact with other work equipment or the wall surface of the work room.

  An object of the present invention is to provide a glove sterilization support member that can support a glove with a simple structure so as not to contact a wall surface of a work room or the like, and an isolator using the same.

  To solve the above problems, an example of the "support member for glove sterilization" of the present invention is a glove sterilization support member that supports a glove of an isolator in a state where the glove is extended into a work room, and includes an arm portion of the glove. A strut extending from the hand to the hand, a strut portion bent at the middle bend portion, a reinforcing portion connecting the strut portions on both sides of the bend portion, and a ring shape located near the bend portion and expanding the arm portion of the glove An arm portion enlarged portion, a ring-shaped palm portion enlarged portion located at the tip side of the support portion and expanding the palm portion of the glove, and a tube inserted into the finger portion of the glove attached to the tip of the support portion And a mounting portion provided on the rear end side of the support portion and for attaching the glove sterilization support member to the glove port of the isolator.

  In addition, to give an example of the “isolator” of the present invention, a work room, a glove provided on a front door of the work room, and a glove inserted into the glove at the time of sterilization to support the glove extended into the work room. An isolator comprising a glove sterilization support member, wherein the glove sterilization support member extends from an arm portion of the glove toward the user's hand, and is bent at an intermediate bent portion, and is provided on both sides of the bent portion. And a ring-shaped arm-enlarged portion that is located near the bent portion and extends the arm of the glove, and a ring-shaped arm that is located on the tip side of the strut and expands the palm of the glove. A palm enlarged portion, a tube attached to the finger of the glove attached to the forefront of the support portion, and a support member provided at the rear end of the support portion for sterilizing the glove and a glove port of the isolator. A mounting portion for mounting to those with a.

  ADVANTAGE OF THE INVENTION According to this invention, the support member for glove sterilization which can support a glove so that it may not contact the wall surface of a work room etc., and an isolator using the same can be provided.

It is a front view showing an example of an isolator device. It is a right side view of the isolator apparatus of FIG. FIG. 2 is a diagram illustrating a flow of an airflow during operation of the isolator device of FIG. 1. FIG. 2 is a diagram showing a flow of an air flow at the time of sterilization of the isolator device of FIG. 1. It is a perspective view which shows the support member for glove sterilization of Example 1 of this invention. It is the front view and side view which show the support member for glove sterilization of Example 1 of this invention. It is a figure which shows the state which supported the glove with the support member for glove sterilization of Example 1. FIG. FIG. 4 is a schematic diagram illustrating an isolator device according to a second embodiment of the present invention. It is the front view and side view which show the support member for glove sterilization of Example 3 of this invention.

  Prior to the description of the embodiments, an isolator device to which the present invention is applied will be described. 1 and 2 are a front view and a side view, respectively, showing an example of the isolator device. 3 and 4 show internal cross-sectional views thereof.

  In the main isolator room 10, a work room 12 for handling a sample such as a pathogen is provided in a case (housing). An air-tight air-supply damper 14 is provided on the upper part of the case, and takes in air from outside the isolator.

  A fan 16 is provided in the upper part of the working chamber 12, and a HEPA filter 18 and a punching plate 20 are provided downstream thereof, so that clean rectified air is supplied to the working chamber 12. A slit is provided in the lower part of the working chamber 12, and the air discharged from the slit returns to the upstream side of the fan 16, and the air circulates. Part of the air is discharged to the outside from an airtight damper 22 for exhaust provided on the upper surface of the case.

  A front door 23 made of glass or resin is attached to the front side of the work room 12, and an opening is opened in the front door 23, and a plurality (left side, center, right side in the figure) for attaching work gloves. Glove port 24 is provided. The glove port 24 is provided with a glove 25 for handling a sample in the working room (FIG. 2).

  A pass box 40 is attached to a side surface of the work chamber 12 via a connecting portion 48. The pass box 40 is provided with a circulation fan 42 and a HEPA filter 44 at an upper part, and a punching plate 44 at a lower part, so that air is circulated when the pass box is operated. A pass box side opening / closing door 26 is provided on the pass box side of the work chamber 12, and a sample or the like is carried in / out through the pass box 40.

  The isolator device includes a sterilizing gas generator 50 used for sterilization, and supplies a sterilizing gas such as hydrogen peroxide gas to the main isolator room 10 from a condition (going) path 54.

  The sterilizing gas returns from the pass box 40 to the sterilizing gas generator 50 through a condition (return) path 52. The isolator main chamber 10 is provided with an aeration path 56 for removing a sterilizing gas after the sterilization process is completed (FIG. 2).

  The flow of air during normal work of processing a sample in the work room will be described with reference to FIG. Air is taken in from the outside of the isolator by the airtight damper 14 for air supply. Air is sent to the pressurized chamber by the fan 16, and clean and aligned air is sent into the working chamber 12 by the HEPA filter 18 and the punching plate 20 on the downstream side.

  The air in the working room is exhausted from a slit provided in the lower part of the working room, returns to the upstream side of the fan 16, and circulates. Part of the air is discharged from the airtight damper 22 for exhaust to the outside. Thus, by supplying clean and aligned air to the work chamber 12, contamination of the sample during the work can be prevented.

  When changing the patient tissue to be handled or when changing the type of pathogen or the like to be handled, it is necessary to sterilize the glove used in the work room or in the work. The flow of sterilization gas during sterilization will be described with reference to FIG. At the time of sterilization, the airtight damper 14 for air supply and the airtight damper 22 for exhaust air are closed to shut off the flow of air to the outside of the isolator.

  For example, hydrogen peroxide gas generated by the sterilizing gas generator 50 is supplied to the flow path of the main isolator chamber. The sterilizing gas is sent into the pressurized chamber by the fan 16, passes through the HEPA filter 18 and the punching plate 20, and is sent into the working chamber 12. At the time of sterilization, the opening / closing door 26 on the pass box side is opened, and the sterilizing gas in the work room is sent to the pass box 40.

  The sterilizing gas returns to the sterilizing gas generator 50 through the pass box 40. In this way, by circulating the sterilizing gas to the isolator including the working chamber, the isolator including the working chamber and the working glove can be sterilized.

The sterilization process is performed as follows.
(1) Dehumidification process The humidity is reduced by dry air. By lowering the humidity, the required concentration of sterilizing gas (eg, aqueous hydrogen peroxide gas) is maintained below the saturation level during subsequent conditioning and decontamination steps. The return air is dried and heated through a drying cartridge.
(2) Conditioning process While the sterilant is being injected into the air stream, the dry air continues to circulate until just before the sterilizing gas leaves the equipment. The condition step is a step for quickly reaching a target sterilization concentration.
(3) Decontamination process The sterilizing agent is used to maintain the sterilizing gas concentration in the entire isolator with a sterilizing agent for a specific period of time, and sterilize the working room and working gloves.
(4) Aeration Step The injection of the sterilizing agent is stopped, and dry air is circulated for a certain period of time in order to reduce the sterilizing gas concentration in the isolator and the connection hose.

  The work glove is made of thin rubber, and when the worker pulls out the arm from the glove, the work glove hangs down and contacts the surface of the work equipment in the work room or the wall of the work room, Fingers may overlap and come into contact, resulting in inadequate sterilization of the contacted parts.

  Hereinafter, embodiments of the present invention for solving this problem will be described with reference to the drawings. In each of the drawings for describing the embodiments, the same components will be given the same names and symbols as much as possible, and the repeated description thereof will be omitted.

  FIG. 5 is a perspective view illustrating the glove sterilizing support member of the first embodiment. FIG. 6A shows a front view of the glove sterilization support member of Example 1, and FIG. 6B shows a side view of the glove sterilization support member.

  The glove sterilization support member 100 according to the first embodiment includes a strut 110 that extends from the arm of the glove to the hand when inserted into the glove, and the strut 110 is bent at a bending portion 115 in the middle. , And comprises a rear support portion 110a on the arm side and a front support portion 110b on the hand side. A bar-shaped reinforcing portion 120 connecting the rear support portion 110a and the front support portion 110b is provided.

  In the vicinity of the bent portion 115 of the support portion, a ring-shaped glove arm expanding portion 130 that expands the glove arm when inserted into the glove is attached. Attachment of the globe arm enlarged portion 130 may be fixed to the support 110 by welding, brazing, or the like at a part of the ring. The glove arm enlarged portion 130 may be attached to the reinforcing portion 120.

  At the tip of the front support 110a, there is attached a ring-shaped palm enlargement 140 that extends the base of the index finger of the glove when inserted into the glove. The glove palm enlarged portion 140 may be attached to the support 110 by welding, brazing, or the like at a part of the ring.

  The front end of the front support 110b can be connected by fitting a vinyl tube 150 therein. The vinyl tube 150 is inserted into the index finger of the glove, and may be long enough to reach the tip of the index finger.

  It is desirable that the tip of the vinyl tube 150 has a length that contacts the finger of the glove. This makes it possible to eliminate or reduce finger wrinkling of the glove.

  The provision of the palm enlarged portion 140 facilitates insertion of the glove sterilizing support member 100 into the palm of the glove. Further, by providing the vinyl tube 150 at the tip of the palm enlarged portion 140, the glove can be easily inserted into the finger portion.

  Further, any material may be used for the vinyl tube 150. However, by using a member softer than the glove, even if the vinyl tube comes into contact with the finger portion of the glove, it is hardly damaged. Since the scratch is hard to be made, the man-hour for inserting the vinyl tube 150 by the user can be reduced.

  When the length of the vinyl tube 150 is longer than the length of the finger of the glove, if the member of the vinyl tube 150 is softer than the glove, the length of the vinyl tube 150 is strictly adjusted because the member is bent in the finger of the glove. There is no necessity, and the convenience of the user in the sterilization operation can be improved.

  At the rear end side of the rear support portion 110a, a substantially ring-shaped mounting portion 160 lacking a part of the circumference is provided for mounting the glove sterilizing support member to the glove port. The mounting portion 160 is provided with a plurality of stopper portions 170 at a plurality of positions in the circumferential direction.

  The support member for glove sterilization of this embodiment can be manufactured by bending a metal, for example, stainless steel wire, and fixing necessary portions by welding, brazing, or the like.

  The working glove is made of thin rubber, for example, chloroprene rubber having a thickness of 0.4 mm, and when the worker pulls his arm out of the glove, he drops into the working room and comes into contact with working equipment or the surface of the working room. Also, wrinkles on the glove cause the surfaces of the glove to come into contact with each other. The thickness of the glove is preferably about 1.0 mm or less in consideration of workability. However, the present invention can be implemented even when the thickness is 1.0 mm or more.

  Even if the sterilizing gas is supplied in this state, the sterilizing gas may not spread to the surface of the work room or the entire surface of the glove, and sufficient sterilization may not be performed. In addition, the amount of contact of the sterilizing gas at the portion where the surfaces of the gloves come into contact with each other or the portion where the glove contacts the inside of the isolator chamber is smaller than in other places, so that a longer sterilization time is required.

  Therefore, at the time of sterilization, the support member for glove sterilization of the present embodiment is inserted into the work glove, and the work glove is supported in the work room to reduce the contacting portion, thereby enabling efficient sterilization work. .

  The ring-shaped mounting part 160 with a part of the circumference cut away is shrunk, inserted into the glove port provided on the front door, and the mounting part 160 is expanded by spring force to mount and fix the glove sterilizing support member to the glove port. I do. Since the mounting portion 160 is provided with the plurality of stopper portions 170, the insertion position of the glove sterilizing support member is defined, and the glove is not damaged by excessive insertion.

  A bent portion 115 is provided in the support 110 of the glove sterilizing support member, and a reinforcing portion 120 connecting the front support 110b and the rear support 110a is attached. A ring-shaped glove arm enlarged portion 130 is provided near the bent portion 115.

  That is, the glove arm enlarged portion 130 is provided closer to the bending portion 115 than the center of the rear support portion 110a. The glove arm enlarged portion 130 can be provided on the bent portion 115 side of the front support portion 110b with respect to the center portion, but when provided on the rear support portion 110a side, it is substantially parallel to the mounting portion 160. Therefore, it becomes easier to support the glove. Further, insertion into the glove is facilitated.

  Since the arm portion of the glove is supported by the reinforcing portion 120 and the ring-shaped glove arm portion enlarging portion 130, the glove near the bent portion can be supported while suppressing the generation of wrinkles. In addition, the weight of the glove is supported by the support 110, but the support strength can be increased by the reinforcement 120.

  Further, when the depth of the work chamber is shorter than the length of the glove, if the glove is supported horizontally, the tip of the glove may come into contact with the back of the work chamber. In the glove sterilization support member of the present embodiment, since the strut portion 110 is bent at the bending portion 115, the tip of the glove can be supported in the work room without contacting the front end of the work room.

  At the tip of the front support 110a, a ring-shaped globe palm enlarged portion 140 is attached, which expands the base of the index finger of the glove when inserted into the glove. The front end of the front support 110b can be connected by fitting a vinyl tube 150, and the vinyl tube 150 to be inserted into the index finger of the glove can be attached.

  By adjusting the length of the vinyl tube 150 according to the length of the finger of the glove, a state in which wrinkles are small can be maintained. Further, by inserting the vinyl tube 150 into the forefinger portion and expanding the base of the forefinger by the ring-shaped palm enlarged portion 140, the tip of the glove is generally widened, and the generation of wrinkles and the overlapping of surfaces are suppressed.

  The finger of the glove has a large angle between the thumb and the index finger, but has a small angle between the index finger, the middle finger, the ring finger, and the little finger. By supporting the index finger with the vinyl tube 150 or the like, it is possible to prevent each finger of the glove from touching.

  The ring-shaped globe arm enlarged portion 130, the ring-shaped glove palm enlarged portion 140, and the substantially ring-shaped mounting portion 160 are respectively attached to the support portion by welding, brazing, or the like at a part of the ring-shaped periphery. The structure is simple.

  When the support member for glove sterilization is inserted into the glove, the strut portion 110 and the reinforcing portion 120 contact the glove over the entire length to support the glove, thereby suppressing the generation of wrinkles due to the hanging of the glove. Can be. Even when wrinkles occur, the shape is such that the glove is placed on the support portion 110 and the reinforcing portion 120, so that overlapping of the wrinkles is suppressed, and efficient sterilization work can be realized.

  FIG. 7 shows a state in which the glove sterilizing support member of the present embodiment is inserted into the working glove. As can be seen in the figure, the surfaces of the glove do not come into contact with each other at the arms of the glove, and the fingers at the tip do not come into contact with each other.

  According to the glove sterilizing support member of the present embodiment, the working glove can be supported in the working room in a spread state with a simple structure, and the working room of the working glove and the isolator can be effectively sterilized. Can be.

  As shown in FIG. 4, at the time of sterilization, the pass box-side opening / closing door 26 of the work chamber 12 is opened so that the sterilizing gas flows to the pass box 40 through the connecting portion 48. Since the glove mounting opening on the pass box side (right side) shown in FIG. 1 is provided near the pass box side opening / closing door 26, when the pass box side opening / closing door 26 is opened as shown in FIG. The tip of the glove may come into contact with the pass box side opening / closing door 26.

  This embodiment solves this problem, and FIG. 8 shows a plan view near the pass box side opening / closing door 26. The glove sterilization support member 100 is usually attached so that the front side support portion 110b rises upward. In this embodiment, the glove sterilization support member 100 on the pass box side is rotated 90 ° right, The front support portion 110b is attached so as to enter the connection portion 48 with the pass box and the pass box 40.

  Therefore, the tip of the glove faces the back of the pass box 40 or the back of the connecting portion 48 with the pass box. In the present embodiment, a slit for sucking a sterilizing gas is provided on the back of the pass box or the back of the connecting portion on the extension of the tip of the glove.

  In FIG. 8, reference numeral 47 denotes a slit provided on the back of the pass box, and reference numeral 49a denotes a slit provided on the back of the connecting portion 48. The slit for sucking the sterilizing gas may be provided on the bottom surface of the connecting portion 48 as indicated by reference numeral 49b.

  By providing a slit for aspirating sterilizing gas on the extension of the tip of the glove or on the bottom of the tip of the glove, the tip of the glove can be stretched by airflow and effectively sterilized. Can be suppressed.

  According to the present embodiment, the work glove arranged on the pass box side can be satisfactorily sterilized.

  In the third embodiment, the glove sterilizing support member of the present invention is provided with a drive unit for moving the tip end side of the column.

  FIG. 9A is a front view of the glove sterilizing support member of the present embodiment, and FIG. 9B is a side view of the glove sterilizing support member of the present embodiment. As shown in the drawing, a driving section 180 is provided in a part of the support section 110 so as to be operated by an operation section 190.

  By periodically moving the front support up and down or left and right by the driving device at the time of sterilization, the working glove into which the glove sterilizing support member is inserted can be moved up and down or left and right. Thereby, the sterilizing gas in the working chamber can be stirred, and the stagnation of the airflow can be suppressed.

  Further, at the time of sterilization, the front support portion is moved by the driving device to move the position of the glove. This allows the airflow to flow along the moved glove, so that the airflow of the sterilizing gas can be controlled and the sterilization time can be reduced. For example, the airflow may be stagnated in the corners of the working chamber. However, the airflow can be effectively sterilized by changing the flow of the airflow using the glove sterilizing support member of the present embodiment.

Reference Signs List 10 Isolator main room 12 Work room 14 Airtight damper 16 for air supply Fan 18 HEPA filter 20 Punching plate 22 Airtight damper 23 for exhaust 23 Front door 24 Globe port 25 Glove 26 Pass box side opening / closing door 40 Pass box 42 Circulating fan 44 HEPA filter 46 Punching plate 47 Pass box rear slit 48 Connecting part 49a Connecting part rear slit 49b Connecting part bottom slit 50 Sterilizing gas generator 52 Condition (return) path 54 Condition (going) path 56 Aeration path 100 Glove sterilization support member 110 Column 115 Bending part 120 Reinforcing part 130 Glove arm expanding part 140 Glove palm expanding part 150 Vinyl tube 160 Mounting part 170 Stopper part 180 Drive part 190 Operating part

Claims (16)

A glove sterilization support member that supports the isolator glove in a state where the glove is extended into the work room,
A strut extending from the arm of the glove toward the hand and bent at the middle bend,
A reinforcing portion connecting the strut portions on both sides of the bending portion,
A ring-shaped arm enlarged portion that is located near the bent portion and expands the arm of the glove;
A ring-shaped palm expanding section located on the tip side of the support section and expanding the palm of the glove,
A tube attached to the finger of the glove attached to the tip of the strut,
A mounting portion that is provided on the rear end side of the support portion and attaches the glove sterilizing support member to the glove port of the isolator.
A support member for glove sterilization comprising: The support member for glove sterilization according to claim 1,
The glove sterilization support member, wherein the support portion includes a rear support portion connected to the bending portion from the arm portion side of the glove, and a front support portion connected to the bending portion from the hand side. . The support member for glove sterilization according to claim 1,
The support member for sterilizing gloves, wherein the tube is a vinyl tube inserted into the index finger of a glove. The support member for glove sterilization according to claim 1,
A support member for glove sterilization, wherein the attachment portion is a substantially ring-shaped member lacking a part of a circumference. The support member for glove sterilization according to claim 4,
A support member for glove sterilization, wherein the attachment portion includes a plurality of stopper portions for defining an insertion position into the glove. The support member for glove sterilization according to claim 1,
The support member for sterilizing gloves, wherein the support portion, the reinforcing portion, the enlarged arm portion, the enlarged palm portion, and the attachment portion are made of a metal wire. The support member for glove sterilization according to claim 1,
A support member for glove sterilization, comprising: a drive unit for moving a tip end side of the support portion at a part of the support portion. A working room, a glove provided at a front door of the working room, and an isolator including a glove sterilizing support member that is inserted into the glove during sterilization and supports the glove in a state where the glove is extended into the working room.
The glove sterilizing support member,
A strut extending from the arm of the glove toward the hand and bent at the middle bend,
A reinforcing portion connecting the strut portions on both sides of the bending portion,
A ring-shaped arm enlarged portion that is located near the bent portion and expands the arm of the glove;
A ring-shaped palm expanding section located on the tip side of the support section and expanding the palm of the glove,
A tube attached to the finger of the glove attached to the tip of the strut,
An isolator provided on a rear end side of the support portion and attaching a glove sterilizing support member to a glove port of the isolator. The isolator according to claim 8,
The isolator according to claim 1, wherein the support portion includes a rear support portion connected to the bent portion from the arm portion side of the glove, and a front support portion connected to the bent portion from the hand side. The isolator according to claim 8,
The tube of the glove sterilizing support member is a vinyl tube inserted into the index finger of the glove. The isolator according to claim 8,
A pass box connected to the work chamber;
An isolator, wherein the glove sterilizing support member on the pass box side is attached such that a tip is located in the pass box during sterilization. The isolator according to claim 11,
An isolator characterized in that a slit for sucking gas is provided on a back surface of the pass box on an extension of a tip of the glove located in the pass box. The isolator according to claim 8,
A connection unit that connects the work chamber and the pass box;
The support member for glove sterilization on the pass box side is attached at the time of sterilization so that the tip is located on the connecting portion side,
An isolator characterized in that a slit for sucking gas is provided on a back surface of the connecting portion and / or a bottom surface of the connecting portion on an extension of a glove tip. The isolator according to claim 8,
An isolator characterized in that a drive part for moving the tip side of the support part is provided on a part of the support part of the glove sterilizing support member, and the position of the glove is movable. The isolator according to claim 8,
An isolator characterized in that a drive part for periodically driving the distal end side of the support part is provided on a part of the support part of the glove sterilizing support member, and the glove can be driven up and down or left and right. The isolator according to claim 8,
In addition, it has a pass box and a sterilizing gas generator,
An isolator, wherein during sterilization, sterilizing gas supplied from the sterilizing gas generator to the working chamber returns to the sterilizing gas generator through the pass box.

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