JP6654147B2 - 張力調節を伴う組織移植片固定 - Google Patents
張力調節を伴う組織移植片固定 Download PDFInfo
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- JP6654147B2 JP6654147B2 JP2016567821A JP2016567821A JP6654147B2 JP 6654147 B2 JP6654147 B2 JP 6654147B2 JP 2016567821 A JP2016567821 A JP 2016567821A JP 2016567821 A JP2016567821 A JP 2016567821A JP 6654147 B2 JP6654147 B2 JP 6654147B2
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- screw
- suture
- tissue graft
- fixation device
- bone
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- 210000000988 bone and bone Anatomy 0.000 claims description 63
- 210000001519 tissue Anatomy 0.000 claims description 45
- 239000007943 implant Substances 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 3
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 2
- 229910001220 stainless steel Inorganic materials 0.000 claims description 2
- 239000010935 stainless steel Substances 0.000 claims description 2
- 239000010936 titanium Substances 0.000 claims description 2
- 229910052719 titanium Inorganic materials 0.000 claims description 2
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 claims description 2
- 239000010937 tungsten Substances 0.000 claims description 2
- 229910052721 tungsten Inorganic materials 0.000 claims description 2
- 210000001264 anterior cruciate ligament Anatomy 0.000 description 12
- 238000000034 method Methods 0.000 description 11
- 210000002303 tibia Anatomy 0.000 description 11
- 210000002435 tendon Anatomy 0.000 description 6
- 210000000689 upper leg Anatomy 0.000 description 5
- 238000003780 insertion Methods 0.000 description 4
- 230000037431 insertion Effects 0.000 description 4
- 238000009795 derivation Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 240000007643 Phytolacca americana Species 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 210000003041 ligament Anatomy 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 230000004983 pleiotropic effect Effects 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 230000000250 revascularization Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/16—Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans
- A61B17/17—Guides or aligning means for drills, mills, pins or wires
- A61B17/1796—Guides or aligning means for drills, mills, pins or wires for holes for sutures or flexible wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0805—Implements for inserting tendons or ligaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/064—Surgical staples, i.e. penetrating the tissue
- A61B17/0642—Surgical staples, i.e. penetrating the tissue for bones, e.g. for osteosynthesis or connecting tendon to bone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0414—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors having a suture-receiving opening, e.g. lateral opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0427—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors having anchoring barbs or pins extending outwardly from the anchor body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
- A61F2002/0817—Structure of the anchor
- A61F2002/0823—Modular anchors comprising a plurality of separate parts
- A61F2002/0829—Modular anchors comprising a plurality of separate parts without deformation of anchor parts, e.g. fixation screws on bone surface, extending barbs, cams, butterflies, spring-loaded pins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
- A61F2002/0847—Mode of fixation of anchor to tendon or ligament
- A61F2002/0852—Fixation of a loop or U-turn, e.g. eyelets, anchor having multiple holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
- A61F2002/0847—Mode of fixation of anchor to tendon or ligament
- A61F2002/0858—Fixation of tendon or ligament between anchor and bone, e.g. interference screws, wedges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
- A61F2002/0847—Mode of fixation of anchor to tendon or ligament
- A61F2002/0864—Fixation of tendon or ligament between anchor elements, e.g. by additional screws in the anchor, anchor crimped around tendon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
- A61F2002/0847—Mode of fixation of anchor to tendon or ligament
- A61F2002/087—Anchor integrated into tendons, e.g. bone blocks, integrated rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
- A61F2002/0876—Position of anchor in respect to the bone
- A61F2002/0882—Anchor in or on top of a bone tunnel, i.e. a hole running through the entire bone
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Rheumatology (AREA)
- Rehabilitation Therapy (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dentistry (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
Description
本出願は、2014年5月15日に出願された米国仮特許出願第61/993,336号の優先権を主張し、その全体の内容が、本明細書において参照により組み込まれている。
15 主体部
20、25 縫合糸貫通孔
30 球状丸めネジ貫通孔、球状丸め凹所
35、40 スパイク部
45、50 主スパイク部
55、60 先細り先端部
100 脛骨トンネル
105 脛骨
110 拡張器
115 槌
130 ドリル案内部
135 BTB移植片
137 基部
140 ドリル通路
145 遠位端
147 第1のカニューレ挿入部
150 第2のカニューレ挿入部
160 縫合糸
170 縫合糸
175 大腿骨側
180 骨ブロック
200 組織移植片固定装置
205 案内ワイヤ
210 衝突体器具
300 組織移植片固定装置
400 組織移植片固定装置
405 木槌
410 衝突体
500 ネジ
505 貫通孔
510 組織移植片固定装置
515 案内ワイヤ
520、525 縫合糸の端
Claims (8)
- 球状丸めネジ貫通孔を挟んで位置決めされた一対の縫合糸貫通孔が設けられる主体部であって、前記一対の縫合糸貫通孔が縫合糸を受け入れる大きさとされ、前記球状丸めネジ貫通孔が固定ネジの丸め頭部を受け入れる大きさとされる、主体部と、
互いに実質的に平行に、前記主体部の下側から延びる2つのスパイク部であって、所定距離で離間され、トンネルが形成された骨へと突き刺されるように適合される2つのスパイク部と、を備え、
前記固定ネジの前記丸め頭部が球状に丸められてなり、かつ、
前記2つスパイク部の各々は、前記球状丸めネジ貫通孔及び前記一対の縫合糸貫通孔が整列する線上に略整列するように、前記一対の縫合糸貫通孔の外側に配設されている
組織移植片固定装置。 - 前記2つのスパイク部と、前記球状丸めネジ貫通孔内に配置された前記固定ネジとの配置が、形成された前記骨の前記トンネルへの案内を可能にする、請求項1に記載の組織移植片固定装置。
- 前記主体部が略平坦な板の形で形成される、請求項1または2に記載の組織移植片固定装置。
- 前記主体部と前記2つのスパイク部とが、ステンレス鋼、チタン、タングステン、およびポリマ材料から成る群から選択される材料から構築される、請求項1〜3のいずれか1項に記載の組織移植片固定装置。
- 前記2つのスパイク部の各々が、
主スパイク部と、
先細り先端部と
を備える、請求項1〜4のいずれか1項に記載の組織移植片固定装置。 - 前記先細り先端部が多面的である、請求項5に記載の組織移植片固定装置。
- 前記先細り先端部が、45度の角度で、形成された前記骨の前記トンネルの内部を向いて位置決めされる、請求項5または6に記載の組織移植片固定装置。
- 前記球状丸めネジ貫通孔が前記固定ネジの角度付けを可能にする、請求項1〜7のいずれか1項に記載の組織移植片固定装置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461993336P | 2014-05-15 | 2014-05-15 | |
US61/993,336 | 2014-05-15 | ||
PCT/US2015/031055 WO2015175922A1 (en) | 2014-05-15 | 2015-05-15 | Tissue graft fixation with tension adjustment |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2017520289A JP2017520289A (ja) | 2017-07-27 |
JP2017520289A5 JP2017520289A5 (ja) | 2018-06-14 |
JP6654147B2 true JP6654147B2 (ja) | 2020-02-26 |
Family
ID=53277085
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016567821A Active JP6654147B2 (ja) | 2014-05-15 | 2015-05-15 | 張力調節を伴う組織移植片固定 |
Country Status (10)
Country | Link |
---|---|
US (1) | US20170239037A1 (ja) |
EP (1) | EP3142601A1 (ja) |
JP (1) | JP6654147B2 (ja) |
KR (1) | KR20170005470A (ja) |
CN (1) | CN106456316B (ja) |
AU (1) | AU2015258930A1 (ja) |
BR (1) | BR112016026485A2 (ja) |
MX (1) | MX2016014943A (ja) |
RU (1) | RU2016148699A (ja) |
WO (1) | WO2015175922A1 (ja) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017210659A1 (en) * | 2016-06-02 | 2017-12-07 | Armington Sam | Adjustable cleat and suture |
US10722344B2 (en) | 2016-06-02 | 2020-07-28 | Parcus Medical, Llc | Adjustable fixation device |
WO2019055723A1 (en) * | 2017-09-15 | 2019-03-21 | Dsm Ip Assets, B.V. | MEDICAL FIXING DEVICE FOR POLYMERIC CABLES |
WO2020010292A1 (en) | 2018-07-06 | 2020-01-09 | Neal Fearnot | Storage devices, loading devices, delivery systems kits, and associated methods |
US11446134B2 (en) | 2020-02-24 | 2022-09-20 | Community Blood Center | Suture guide devices for preparing tendon grafts and methods incorporating the same |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
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US4988351A (en) * | 1989-01-06 | 1991-01-29 | Concept, Inc. | Washer for use with cancellous screw for attaching soft tissue to bone |
US5352229A (en) * | 1993-05-12 | 1994-10-04 | Marlowe Goble E | Arbor press staple and washer and method for its use |
USD364462S (en) * | 1994-03-28 | 1995-11-21 | Michelson Gary K | Spinal fixation staple |
CA2551185C (en) * | 1994-03-28 | 2007-10-30 | Sdgi Holdings, Inc. | Apparatus and method for anterior spinal stabilization |
EP1510188B1 (en) * | 1997-07-23 | 2015-03-18 | Arthrotek, Inc. | Apparatus for tibial fixation of soft tissue |
US5931869A (en) * | 1997-07-23 | 1999-08-03 | Arthrotek, Inc. | Apparatus and method for tibial fixation of soft tissue |
US6117139A (en) * | 1998-12-25 | 2000-09-12 | Nagoya Screw Mfg., Co., Ltd. | Ligament graft-securing device |
JP3370300B2 (ja) * | 1998-12-25 | 2003-01-27 | メイラ株式会社 | 移植靭帯固定用器具 |
US6464706B1 (en) * | 1999-06-10 | 2002-10-15 | Thomas F. Winters | Tissue fixation device and method |
FR2804598B1 (fr) * | 2000-02-07 | 2002-04-26 | Jacques Afriat | Dispositif de fixation d'un implant ou d'un transplant formant ligament prothetique sur un os |
JP2002272756A (ja) * | 2001-03-16 | 2002-09-24 | Yoshio Koga | 膝関節の前十字靱帯再建手術用器具およびその再建靱帯脛骨側固定器具 |
US8317815B2 (en) * | 2006-10-06 | 2012-11-27 | Surgiquest, Inc. | Visualization trocar |
US8123749B2 (en) * | 2005-03-24 | 2012-02-28 | Depuy Spine, Inc. | Low profile spinal tethering systems |
US7842037B2 (en) * | 2006-09-27 | 2010-11-30 | Dupuy Products, Inc. | Flexible bone fixation device |
EP2081502B8 (en) * | 2006-10-31 | 2014-04-02 | Orthonoble Inc. | A medical device for attaching tissue to bone |
CN201389046Y (zh) * | 2009-04-08 | 2010-01-27 | 黄长明 | 一种缝线紧缩固定装置 |
US8808335B2 (en) * | 2010-03-08 | 2014-08-19 | Miami Device Solutions, Llc | Locking element for a polyaxial bone anchor, bone plate assembly and tool |
-
2015
- 2015-05-15 KR KR1020167034728A patent/KR20170005470A/ko unknown
- 2015-05-15 JP JP2016567821A patent/JP6654147B2/ja active Active
- 2015-05-15 BR BR112016026485A patent/BR112016026485A2/pt not_active Application Discontinuation
- 2015-05-15 RU RU2016148699A patent/RU2016148699A/ru unknown
- 2015-05-15 CN CN201580025218.5A patent/CN106456316B/zh not_active Expired - Fee Related
- 2015-05-15 EP EP15726818.6A patent/EP3142601A1/en not_active Withdrawn
- 2015-05-15 US US15/310,163 patent/US20170239037A1/en not_active Abandoned
- 2015-05-15 MX MX2016014943A patent/MX2016014943A/es unknown
- 2015-05-15 AU AU2015258930A patent/AU2015258930A1/en not_active Abandoned
- 2015-05-15 WO PCT/US2015/031055 patent/WO2015175922A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
CN106456316A (zh) | 2017-02-22 |
KR20170005470A (ko) | 2017-01-13 |
US20170239037A1 (en) | 2017-08-24 |
AU2015258930A1 (en) | 2016-11-24 |
BR112016026485A2 (pt) | 2017-08-15 |
WO2015175922A1 (en) | 2015-11-19 |
CN106456316B (zh) | 2019-09-03 |
JP2017520289A (ja) | 2017-07-27 |
MX2016014943A (es) | 2017-04-11 |
EP3142601A1 (en) | 2017-03-22 |
RU2016148699A (ru) | 2018-06-18 |
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