JP6644094B2 - ホログラフィック装置および物体選別システム - Google Patents

ホログラフィック装置および物体選別システム Download PDF

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Publication number
JP6644094B2
JP6644094B2 JP2017567333A JP2017567333A JP6644094B2 JP 6644094 B2 JP6644094 B2 JP 6644094B2 JP 2017567333 A JP2017567333 A JP 2017567333A JP 2017567333 A JP2017567333 A JP 2017567333A JP 6644094 B2 JP6644094 B2 JP 6644094B2
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hologram
fluid channel
property
processing unit
present
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Japanese (ja)
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JP2018528450A (ja
JP2018528450A5 (https=
Inventor
ベンディックス・シュナイダー
ピーテル・ビーンストマン
ヨニ・ダンブレ
ヘールト・ファンメールベーク
リースベト・ラハー
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Universiteit Gent
Interuniversitair Microelektronica Centrum vzw IMEC
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Universiteit Gent
Interuniversitair Microelektronica Centrum vzw IMEC
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02Investigating particle size or size distribution
    • G01N15/0205Investigating particle size or size distribution by optical means
    • G01N15/0227Investigating particle size or size distribution by optical means using imaging; using holography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N15/147Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/02Details of features involved during the holographic process; Replication of holograms without interference recording
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/04Processes or apparatus for producing holograms
    • G03H1/0443Digital holography, i.e. recording holograms with digital recording means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/149Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012Red blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/016White blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02Investigating particle size or size distribution
    • G01N15/0205Investigating particle size or size distribution by optical means
    • G01N15/0227Investigating particle size or size distribution by optical means using imaging; using holography
    • G01N2015/0233Investigating particle size or size distribution by optical means using imaging; using holography using holography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N2015/1454Optical arrangements using phase shift or interference, e.g. for improving contrast
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1493Particle size
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/04Processes or apparatus for producing holograms
    • G03H1/0443Digital holography, i.e. recording holograms with digital recording means
    • G03H2001/0447In-line recording arrangement
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H2226/00Electro-optic or electronic components relating to digital holography
    • G03H2226/02Computing or processing means, e.g. digital signal processor [DSP]
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H2226/00Electro-optic or electronic components relating to digital holography
    • G03H2226/11Electro-optic recording means, e.g. CCD, pyroelectric sensors

Landscapes

  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Computing Systems (AREA)
  • Theoretical Computer Science (AREA)
  • Holo Graphy (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2017567333A 2015-06-30 2016-06-28 ホログラフィック装置および物体選別システム Expired - Fee Related JP6644094B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15174589.0 2015-06-30
EP15174589 2015-06-30
PCT/EP2016/065068 WO2017001438A1 (en) 2015-06-30 2016-06-28 Holographic device and object sorting system

Publications (3)

Publication Number Publication Date
JP2018528450A JP2018528450A (ja) 2018-09-27
JP2018528450A5 JP2018528450A5 (https=) 2019-06-20
JP6644094B2 true JP6644094B2 (ja) 2020-02-12

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JP2017567333A Expired - Fee Related JP6644094B2 (ja) 2015-06-30 2016-06-28 ホログラフィック装置および物体選別システム

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Country Link
US (1) US10295451B2 (https=)
EP (1) EP3317728B1 (https=)
JP (1) JP6644094B2 (https=)
CN (1) CN107735733B (https=)
CA (1) CA2988037A1 (https=)
WO (1) WO2017001438A1 (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12109593B2 (en) 2015-07-16 2024-10-08 Sortera Technologies, Inc. Classification and sorting with single-board computers
US12246355B2 (en) 2015-07-16 2025-03-11 Sortera Technologies, Inc. Sorting of Zorba
US12103045B2 (en) 2015-07-16 2024-10-01 Sortera Technologies, Inc. Removing airbag modules from automotive scrap
US10722922B2 (en) 2015-07-16 2020-07-28 UHV Technologies, Inc. Sorting cast and wrought aluminum
US12551931B2 (en) 2015-07-16 2026-02-17 Sortera Technologies, Inc. Classifying of materials with contaminants
US12403505B2 (en) 2015-07-16 2025-09-02 Sortera Technologies, Inc. Sorting of aluminum alloys
US10710119B2 (en) 2016-07-18 2020-07-14 UHV Technologies, Inc. Material sorting using a vision system
US12194506B2 (en) 2015-07-16 2025-01-14 Sortera Technologies, Inc. Sorting of contaminants
US12017255B2 (en) 2015-07-16 2024-06-25 Sortera Technologies, Inc. Sorting based on chemical composition
US12290842B2 (en) 2015-07-16 2025-05-06 Sortera Technologies, Inc. Sorting of dark colored and black plastics
US12208421B2 (en) 2015-07-16 2025-01-28 Sortera Technologies, Inc. Metal separation in a scrap yard
US12508628B2 (en) 2015-07-16 2025-12-30 Sortera Technologies, Inc. Sorting between metal alloys
US11969764B2 (en) 2016-07-18 2024-04-30 Sortera Technologies, Inc. Sorting of plastics
US11278937B2 (en) 2015-07-16 2022-03-22 Sortera Alloys, Inc. Multiple stage sorting
US11964304B2 (en) 2015-07-16 2024-04-23 Sortera Technologies, Inc. Sorting between metal alloys
US12280403B2 (en) 2015-07-16 2025-04-22 Sortera Technologies, Inc. Sorting based on chemical composition
US10625304B2 (en) 2017-04-26 2020-04-21 UHV Technologies, Inc. Recycling coins from scrap
WO2018064660A1 (en) * 2016-09-30 2018-04-05 University Of Utah Research Foundation Lensless imaging device
US10408852B2 (en) * 2017-04-26 2019-09-10 Lawrence Livermore National Security, Llc Automated control of microfluidic devices based on machine learning
EP3631693A1 (en) * 2017-05-29 2020-04-08 Universiteit Gent Mixing wave-based computing
JP6928948B2 (ja) * 2017-08-09 2021-09-01 学校法人日本大学 口臭判定装置及びプログラム
CN111164389B (zh) * 2017-08-10 2022-09-02 联邦科学及工业研究组织 用于监测沿通道的材料流动参数的设备和方法
US20200311465A1 (en) * 2017-11-14 2020-10-01 miDiagnostics NV Classification of a population of objects by convolutional dictionary learning with class proportion data
US11280729B2 (en) 2019-03-25 2022-03-22 Asahi Kasei Microdevices Corporation Optical density measuring apparatus and optical waveguide
EP3953655A4 (en) 2019-07-02 2023-01-11 Brentwood Industries, Inc. Cooling tower splash bar hanger and related assembly
WO2021003369A1 (en) * 2019-07-02 2021-01-07 The Regents Of The University Of California Magnetically modulated computational cytometer and methods of use
US11653534B2 (en) 2020-03-05 2023-05-16 Samsung Display Co., Ltd. Display device and electronic apparatus
DE102021205022A1 (de) * 2021-05-18 2022-11-24 Q.ant GmbH Sensoranordnung zur Detektion von Partikelmerkmalen
KR20250073486A (ko) 2022-10-21 2025-05-27 솔테라 테크노롤지스 인코포레이티드 재료 분류를 위한 보정 기법들
KR102740003B1 (ko) * 2022-12-12 2024-12-06 서울대학교산학협력단 홀로그램 스케일링 방법 및 그 장치

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1015640C2 (nl) * 2000-07-06 2002-01-08 Univ Delft Tech Inrichting en werkwijze voor het bepalen van de vorm en/of grootte van kleine deeltjes.
US6760107B1 (en) * 2002-04-12 2004-07-06 Pointsource Technologies, Llc Detection of scattered light from particles
WO2007051170A2 (en) * 2005-10-28 2007-05-03 The Regents Of The University Of California Apparatus and method for improved optical detection of particles in fluid
US8634074B2 (en) * 2010-06-08 2014-01-21 University Corporation For Atmospheric Research Method and system for high volume sample rate holographic particle measurement
WO2012082776A2 (en) * 2010-12-14 2012-06-21 The Regents Of The University Of California Method and device for holographic opto-fluidic microscopy
JP5946193B2 (ja) * 2011-11-24 2016-07-05 国立大学法人東京農工大学 測定装置及び測定方法
EP2602608B1 (en) * 2011-12-07 2016-09-14 Imec Analysis and sorting of biological cells in flow
US10222315B2 (en) * 2014-10-13 2019-03-05 New York University Machine-learning approach to holographic particle characterization
GB2539017B (en) * 2015-06-03 2019-12-18 Toshiba Res Europe Limited An optical measuring device

Also Published As

Publication number Publication date
CN107735733B (zh) 2020-05-26
JP2018528450A (ja) 2018-09-27
EP3317728A1 (en) 2018-05-09
EP3317728B1 (en) 2019-10-30
US20180195945A1 (en) 2018-07-12
CN107735733A (zh) 2018-02-23
WO2017001438A1 (en) 2017-01-05
US10295451B2 (en) 2019-05-21
CA2988037A1 (en) 2017-01-05

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