JP6643690B2 - Pesticide formulation - Google Patents

Description

  The present invention relates to a stabilized pesticide formulation containing an active pesticide such as cyazofamid or amisulbrom. The preparation of the present invention is used for the purpose of controlling pests in the field of agriculture and horticulture.

  Cyazofamid, 4-chloro-2-cyano-1-dimethylsulfamoyl-5- (4-methylphenyl) imidazole, and amisulbrom, 1- (N, N-dimethylsulfamoyl) -3- ( 3-Bromo-6-fluoro-2-methylindol-1-yl) sulfonyl-1,2,4-triazole) is a sulfamoyl compound characterized by having a sulfamoyl group, each of which is described in The Pesticide Manual (Sixteenth). Edition), pages 249 to 250 and pages 38 to 39, which are compounds known as agricultural and horticultural fungicides.

  Hymexazole (5-methylisoxazol-3-ol) is a compound known as an agricultural and horticultural fungicide, as described on pages 622 to 623 of The Pesticide Manual (Sixteenth Edition).

  Patent Literature 1 describes a composition for controlling phytopathogenic bacteria comprising an active ingredient, himexazole and cyazofamid, and a plurality of formulation examples. Patent Document 2 discloses that at least one selected from the group consisting of epoxidized animal and vegetable oils, nonionic polyoxyethylene surfactants, anionic polyoxyethylene surfactants, polyhydric alcohols and basic substances A method for suppressing the decomposition of cyazofamid using the above stabilizer is described. Patent Document 3 discloses that a sulfonate containing an α-olefin sulfonate decomposes a water-soluble pesticide active ingredient such as nitenpyram [water solubility; 0.01 g / ml = 10 g / L or more (20 ° C)]. A method of suppression is described. Further, Patent Document 4 discloses that at least one interface selected from the group consisting of a naphthalene sulfonate formalin condensate, an alkyl naphthalene sulfonate formalin condensate, a dialkylnaphthalene sulfonate formalin condensate, and a polycarboxylate A method in which an activator inhibits the degradation of furazasulfuron is described.

Japanese Patent Application Laid-Open No. 2003-113007 Japanese Patent Application Laid-Open No. 2010-70542 Japanese Patent Application Laid-Open No. 7-291807 Japanese Patent Application Laid-Open No. 2007-262052

Sulfamoyl compounds such as cyazofamide and amisulbrom may degrade the binding site of the sulfamoyl group during long-term storage and tend to be more easily degraded in solid preparations. Therefore, the problem to be solved by the present invention is to provide an agricultural chemical formulation in which sulfamoyl compounds such as cyazofamid and amisulbrom are chemically stabilized, and furthermore, the decomposition of the sulfamoyl compound is suppressed, and the storage stability is improved. An object of the present invention is to provide a pesticide preparation having excellent properties.
Heretofore, it has not been known that hymexazole is involved in suppressing the decomposition of other pesticidal active ingredients. In addition, Patent Document 1 does not describe the storage stability of an active ingredient such as cyazofamide, and does not describe amisulbrom. The stabilizer described in Patent Document 2 only suppresses the decomposition of cyazofamide, and there is no description on a method of suppressing the decomposition of a sulfamoyl compound by a sulfonate. Patent Literature 3 discloses a water-insoluble agrochemical active ingredient such as cyazofamid or amisulbrom [cyazofamid aqueous solubility; 0.107 mg / L (20 ° C, pH 7), amisulbrom aqueous solubility; 0.11 mg / L (20 ° C)]. There is no description on a method for suppressing decomposition. Further, Patent Document 4 does not describe a method for suppressing the decomposition of a sulfamoyl compound such as cyazofamid or amisulbrom.

The present inventors have studied to solve the above-mentioned problems, and as a result, by using a specific sulfonate, decomposition of a sulfamoyl compound such as cyazofamide or amisulbrom (hereinafter, also simply referred to as a sulfamoyl compound of the present invention) is achieved. It has been found that a suppressed chemically stable composition can be prepared, and further, surprisingly, the use of the sulfonate in the presence of hymexazole has a remarkable effect of suppressing the decomposition of the sulfamoyl compound. And completed the present invention.
That is, the present invention relates to the following <1> to <14>.
<1> at least one selected from the group consisting of (a) at least one sulfamoyl compound selected from cyazofamid and amisulbromide, (b) hymexazole and (c) a salt of an α-olefin sulfonate and a naphthalenesulfonic acid formalin condensate. A pesticide formulation characterized by containing one type of sulfonate.
<2> The agricultural chemical formulation according to <1>, wherein the (a) sulfamoyl compound and the (b) himexazole are contained at a weight ratio of 1: 100 to 100: 1.
<3> The agricultural chemical formulation according to <1> or <2>, wherein the (a) sulfamoyl compound and the (b) himexazole are contained in a weight ratio of 1:10 to 10: 1.
<4> The method according to any one of <1> to <3>, wherein the (a) sulfamoyl compound and the (c) sulfonate are contained at a weight ratio of 1:40 to 40: 1. Pesticide formulation.
<5> The method according to any one of <1> to <4>, wherein the (a) sulfamoyl compound and the (c) sulfonate are contained in a weight ratio of 1:15 to 5: 1. Pesticide formulation.
<6> Based on the total amount of the preparation, 0.3 to 90% by weight of (a) the sulfamoyl compound, 0.3 to 90% by weight of (b) himexazole, and 0.1% of (c) the sulfonate. The agricultural chemical formulation according to any one of the above <1> to <5>, which contains the pesticide in an amount of from 60 to 60% by weight.
<7> The agricultural chemical preparation according to any one of <1> to <6>, wherein the preparation is a solid preparation.
<8> The agricultural chemical formulation according to <7>, wherein the solid preparation is a wettable powder, a powder, a wettable powder, a granule, or a water-soluble pack.
<9> characterized by adding (b) hymexazole and (c) at least one sulfonate selected from the group consisting of salts of α-olefin sulfonate and naphthalenesulfonic acid formalin condensate, a) A method for stabilizing an agricultural chemical formulation containing at least one sulfamoyl compound selected from cyazofamid and amisulbrom.
<10> The stabilization method according to <9>, wherein the decomposition of the (a) sulfamoyl compound is suppressed by adding the (b) hymexazole and the (c) sulfonate.
<11> A compounding ratio of the (a) sulfamoyl compound to the (b) himexazole in a weight ratio of 1: 100 to 100: 1, and a combination of the (a) sulfamoyl compound and the (c) sulfonate. The ratio is 1:40 to 40: 1 by weight, and the compounding ratio of the (b) hymexazole and the (c) sulfonate is 1:50 to 50: 1 by weight. The stabilization method according to 9> or <10>.
<12> The compounding ratio of the (a) sulfamoyl compound to the (b) himexazole is 1:10 to 10: 1 by weight, and the compounding ratio of the (a) sulfamoyl compound to the (c) sulfonate. Wherein the weight ratio is 1:15 to 5: 1; and the compounding ratio of the (b) hymexazole and the (c) sulfonate is 1: 2 to 30: 1 by weight, <9> to The stabilization method according to any one of <11>.
<13> The stabilizing method according to any one of <10> to <12>, wherein the preparation is a solid preparation, and the decomposition of the (a) sulfamoyl compound is suppressed in the solid preparation.
<14> The stabilizing method according to <13>, wherein the solid preparation is a wettable powder, a powder, a wettable powder, a granule, or a water-soluble pack.

  According to the present invention, it is possible to improve the storage stability of an agricultural chemical formulation containing at least one sulfamoyl compound selected from cyazofamid and amisulbrom, and to provide an agricultural chemical formulation in which cyazofamid and amisulbrom are chemically stabilized. it can.

The agricultural chemical formulation according to the present invention is selected from the group consisting of (a) at least one sulfamoyl compound selected from cyazofamid and amisulbromide, (b) hymexazole and (c) salts of α-olefin sulfonic acid salt and naphthalene sulfonic acid formalin condensate. It is characterized by containing at least one selected sulfonate.
In the present specification, (a) at least one sulfamoyl compound selected from cyazofamid and amisulbrom is simply referred to as “sulfamoyl compound of the present invention”, (c) α-olefin sulfonate and naphthalenesulfonic acid formalin condensate. At least one sulfonate selected from the group of salts may be simply referred to as “sulfonate of the present invention”, and the pesticide formulation according to the present invention may be simply referred to as “formulation of the present invention”. Further, when simply described as “ppm”, it means “weight ppm”, and “to” is used to mean that the numerical values described before and after it are included as the lower limit and the upper limit.

  The sulfamoyl compound of the present invention is characterized by having a sulfamoyl group. Cyazofamid and amisulbrom may be used alone or in a mixture, but it is more preferable to use cyazofamid alone.

  The compounding ratio of the sulfamoyl compound and himexazole in the preparation of the present invention is usually from 1: 300 to 300: 1, preferably from 1: 100 to 100: 1, more preferably from 1:10 to 10: 1 by weight. . Here, when the sulfamoyl compound is a mixture of cyazofamid and amisulbrom, the blending amount of the sulfamoyl compound means the total amount thereof.

  The compounding ratio of the sulfamoyl compound to the sulfonate of the present invention in the preparation of the present invention is usually 1:50 to 50: 1, preferably 1:40 to 40: 1, more preferably 1:15 to 1:50 by weight. 5: 1. Here, when the sulfamoyl compound is a mixture of cyazofamid and amisulbrom, the blending amount of the sulfamoyl compound means the total amount thereof. When the sulfonate comprises a plurality of salts, the blending amount of the sulfonate means the total amount.

  Examples of the sulfonic acid salt of the present invention include an α-olefin sulfonic acid salt and a salt of a naphthalene sulfonic acid formalin condensate, which may be used alone or in combination. When these are used as a mixture, the compounding ratio of the α-olefin sulfonic acid salt and the salt of the naphthalene sulfonic acid formalin condensate is usually 1: 100 to 100: 1 by weight, preferably 1:40 to 40: 1. , More preferably 1:20 to 20: 1.

  Examples of the α-olefin sulfonic acid salt of the present invention include salts of α-olefin sulfonic acid with alkali metals such as sodium and potassium, and salts with alkaline earth metals such as magnesium and calcium. Specifically, it is a sodium salt of an α-olefin sulfonic acid having 12 to 20 carbon atoms, more specifically, a sodium salt of an α-olefin sulfonic acid having 14 to 18 carbon atoms, an α-olefin having 14 to 16 carbon atoms Examples thereof include sodium sulfonic acid and sodium α-olefin sulfonic acid having 16 to 18 carbon atoms. More specifically, commercially available sulfonic acid salts such as Solpol 5115 (trade name; manufactured by Toho Chemical Industry Co., Ltd .; sodium salt of an α-olefin sulfonic acid having 14 to 18 carbon atoms) are exemplified.

Examples of the salt of the naphthalenesulfonic acid formalin condensate of the present invention include a salt of a naphthalenesulfonic acid formalin condensate and a salt with an alkali metal such as sodium and potassium, and a salt with an alkaline earth metal such as magnesium and calcium. Specifically, a sodium salt of a naphthalenesulfonic acid formalin condensate is suitable. More specifically, NK WG-2 (trade name, manufactured by Takemoto Yushi Co., Ltd.) or Tamol NN8906 (trade name, BASF Japan Co., Ltd.) Commercially available sulfonic acid salts.
(C) The sulfonate contains at least one of a salt of α-olefinsulfonic acid with an alkali metal or an alkaline earth metal and a salt of a naphthalenesulfonic acid formalin condensate with an alkali metal or an alkaline earth metal. And more preferably at least one of a sodium salt of an α-olefin sulfonic acid having 12 to 20 carbon atoms and a sodium salt of a naphthalene sulfonic acid formalin condensate, and an α-olefin having 14 to 18 carbon atoms It is more preferable to contain at least one of a sodium sulfonic acid salt and a sodium salt of a naphthalenesulfonic acid formalin condensate.

  The compounding ratio of Himexazole and the sulfonate salt of the present invention in the preparation of the present invention is usually 1: 200 to 200: 1, preferably 1:50 to 50: 1, more preferably 1: 2 to 30 by weight ratio. : 1. Here, when the sulfonate comprises a plurality of salts, the blending amount of the sulfonate means the total amount thereof.

(A) The total content of at least one sulfamoyl compound selected from cyazofamid and amisulbrom is 0.3 to 90% by weight, preferably 0.5 to 80% by weight, based on the total amount of the preparation of the present invention. And more preferably 0.5 to 50% by weight.
(B) The content of himexazole is 0.3 to 90% by weight, preferably 0.5 to 85% by weight, more preferably 1 to 80% by weight based on the total amount of the preparation of the present invention.
(C) The sum of the content of at least one sulfonate selected from the group of salts of α-olefin sulfonate and naphthalenesulfonic acid formalin condensate is 0.1 to 0.1% based on the total amount of the preparation of the present invention. It is 60% by weight, preferably 0.1 to 40% by weight, and more preferably 0.5 to 30% by weight.

  The preparation of the present invention can be prepared as a solid preparation (eg, powder, wettable powder, wettable powder, granule, water-soluble pack), a surfactant (excluding the sulfonate of the present invention), a carrier, Formulation auxiliaries, such as oil absorbing agents and antidrift agents, can be added as needed. The preparation of the preparation can be carried out according to a usual method in the technical field.

  Examples of the surfactant include a fatty acid salt, a benzoate, an alkyl sulfosuccinate, a dialkyl sulfosuccinate, an alkyl sulfate, an alkyl sulfate, an alkyl diglycol ether sulfate, an alcohol sulfate, an alkyl sulfonate, Lignin sulfonate, alkyl diphenyl ether disulfonate, polystyrene sulfonate, alkyl phosphate, alkyl aryl phosphate, styryl aryl phosphate, polyoxyethylene alkyl ether sulfate, polyoxyethylene alkyl aryl ether sulfate Salt, polyoxyethylene styryl aryl ether sulfate, polyoxyethylene styryl aryl ether sulfate ammonium salt, polyoxyethylene alkyl aryl ether sulfate salt, Anionic surfactants such as oxyethylene alkyl ether phosphate, polyoxyethylene alkyl aryl phosphate, polyoxyethylene styryl aryl ether phosphate or a salt thereof; sorbitan fatty acid ester, glycerin fatty acid ester, fatty acid Polyglyceride, fatty alcohol polyglycol ether, acetylene glycol, acetylene alcohol, oxyalkylene block polymer, polyoxyethylene alkyl ether, polyoxyethylene alkyl aryl ether, polyoxyethylene styryl aryl ether, polyoxyethylene glycol alkyl ether, polyoxyethylene Fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene sorbitol fat Nonionic surfactants such as acid esters, polyoxyethylene glycerin fatty acid esters, polyoxyethylene hydrogenated castor oil, polyoxyethylene castor oil, and polyoxypropylene fatty acid esters; cationic surfactants such as alkoxylated aliphatic amines Surfactants and the like may be mentioned, and if necessary, two or more of these may be used in combination. The total content of the surfactant is 0 to 10% by weight, preferably 2 to 5% by weight, based on the total amount of the preparation of the present invention.

  Examples of the carrier include diatomaceous earth, slaked lime, calcium carbonate, talc, white carbon, bentonite, starch, sugars such as lactose and fructose, sodium carbonate, baking soda, clay, zeolite, ammonium sulfate, ammonium hydrogen sulfate, sodium sulfate, sodium chloride, and chloride. Potassium and the like may be mentioned, and if necessary, two or more of these may be mixed. The total content of the carrier is 0 to 90% by weight, preferably 10 to 50% by weight, based on the total amount of the preparation of the present invention.

  Examples of the oil absorbing agent include silicon dioxide, starch hydrolyzate, kaolin, clay, diatomaceous earth, calcium silicate, acid clay, carbon black, perlite (pearlite) processed product, ultrafine anhydrous aluminum oxide, ultrafine titanium oxide, and base. Magnesium carbonate, magnesium silicate aluminate, silica / alumina synthetic filler, hydrous magnesium silicate, and the like. If necessary, two or more of these may be used. The total content of the oil absorbing agent is from 0 to 60% by weight, preferably from 5 to 30% by weight, based on the total amount of the preparation of the present invention.

  Examples of the drift inhibitor include mineral oil, vegetable oil, ethylene glycol, alkyl phosphate derivative (trade name: Drilles A), liquid paraffin (trade name: Drilles C), and a mixture of two or more of these as necessary. May be. The total content of the anti-drift agent is 0 to 20% by weight, preferably 0.1 to 5% by weight, based on the total amount of the preparation of the present invention.

  Examples of the material of the water-soluble film used in the water-soluble pack include polyvinyl alcohol and polyethylene glycol.

  The use concentration of the preparation of the present invention varies depending on conditions such as the target crop, the method of use, the form of the preparation, and the amount of application, and therefore, it is difficult to unconditionally define the concentration. It is 10000 ppm, preferably 1 to 10000 ppm, more preferably 10 to 1000 ppm. In the case of soil treatment, the amount of the sulfamoyl compound is usually 0.1 g / a to 10000 g / a, preferably 1 g / a to 1000 g / a, and more preferably. Is from 10 g to 100 g / a.

  The formulation of the present invention may optionally contain other pesticides, such as fungicides, insecticides, acaricides, nematicides, soil pesticides, antivirals, attractants, herbicides, plant growth regulators. Can be mixed and used together.

Examples of the active ingredient compound of a bactericide in the other pesticides (generic name; including some applications, or the Japan Plant Protection Association test code) include, for example,
Anilinopyrimidine compounds such as mepanipyrim, pyrimethanil, cyprodinil;
Trias such as 5-chloro-7- (4-methylpiperidin-1-yl) -6- (2,4,6-trifluorophenyl) [1,2,4] triazolo [1,5-a] pyrimidine Zolopyrimidine compounds;
Pyridinamine compounds such as fluazinam;
Triadimefon, bitertanol, triflumizole, etaconazole, etaconazole, propiconazole, propconazole, penconazole, flusilazole (flusilazole), microbutanyl (myclobutanil), cyproconazole ( cyproconazole), tebuconazole, tebuconazole, hexaconazole, furconazole cis (furconazole-cis), prochloraz (prochloraz), metconazole (metconazole), epoxyconazole (epoxiconazole), tetraconazole (tetraconazole), o Oxpoconazole fumarate, prothioconazole, triadimenol, flutriafol, difenoconazole, fluquinconazole azole), fenbuconazole, fenbuconazole, bromuconazole, diniconazole, tricyclazole (tricyclazole), probenazole (probenazole), simeconazole (simeconazole), pefurazoate, pefurazoate, ipconazole, imibenazole Azole compounds such as (imibenconazole), azaconazole, azaconazole, triticonazole, imazalil;
Quinoxaline-based compounds such as quinomethionate;
Dithiocarbamate-based compounds such as maneb, zineb, mancozeb, polycarbamate, metiram, propineb (propineb), thiram;
Organochlorine compounds such as fthalide, chlorothalonil, quintozene;
Imidazole compounds such as benomyl, thiophanate-methyl, carbendazim, thiabendazole, fuberiazole;
Cyanoacetamide-based compounds such as cymoxanil;
Metalaxyl, metalaxyl-M (also known as mefenoxam), oxadixyl, oxadixyl, ofurace, benalaxyl, benalaxyl-M (benalaxyl-M, also known as kiralaxylchiral) )), Furalaxyl, cyprofuram, carboxin, carboxin, oxycarboxin, thifluzamide, thifluzamide, boscalid, bixafen, isotianil, thiadinil Anilide compounds such as sedaxane;
Sulfamide compounds such as dichlofluanid;
Copper-based compounds such as cupric hydroxide and oxine copper;
Organophosphorus compounds such as fosetyl aluminum (fosetyl-Al), tolclofos-Methyl, edifenphos, iprobenfos;
Phthalimide-based compounds such as captan, captafol, and folpet;
Dicarboximide compounds such as procymidone, iprodione, vinclozolin;
Benzanilide compounds such as flutolanil, mepronil, benodanil;
Penthiopyrad (penthiopyrad), penflufen (penflufen), furametopyru (furametpyr), isopyrazam (isopyrazam), silthiofam (silthiopham), fenoxanil (fenoxanil), fenfuram (fenfuram), floxapyroxad (fluxapyroxad), benzobindiflupyr (vin) Amide compounds such as
Benzamide compounds such as fluopyram and zoxamide;
Thiophenamide-based compounds such as isofetamid;
Piperazine-based compounds such as triforine;
Pyridine compounds such as pyrifenox and pyrisoxazole;
Carbinol-based compounds such as fenarimol and nuarimol;
Piperidine compounds such as fenpropidin;
Morpholine-based compounds such as fenpropimorph and tridemorph;
Organotin compounds such as fentin hydroxide and fentin acetate;
Urea-based compounds such as pencicuron;
Cinamic acid-based compounds such as dimethomorph, flumorph, and pyrimorph;
Phenylcarbamate-based compounds such as dietofencarb;
Cyanopyrrole compounds such as fludioxonil and fenpiclonil;
Azoxystrobin (azoxystrobin), kresoxim-methyl, metominostrobin, trifloxystrobin, picoxystrobin, oryzastrobin, oryzastrobin, dimoxistrobin dimoxystrobin), pyraclostrobin, fluoxastrobin, fluoxastrobin, enestroburin, pyraoxystrobin, pyrametostrobin, coumoxystrobin, enoxast Strobilurin-based compounds such as robin (enoxastrobin), phenaminestrobin (fenaminstrobin), fluphenoxystrobin (flufenoxystrobin), triclopyricarb, mandestrobin (mandestrobin);
Oxazolidinone compounds such as famoxadone;
Thiazolecarboxamide compounds such as ethaboxam;
Valinamide compounds such as iprovalicarb, benthiavalicarb-isopropyl;
Acylaminoacid compounds such as valifenalate;
Imidazolinone-based compounds such as fenamidone;
Hydroxyanilide-based compounds such as fenhexamid;
Benzenesulfonamide-based compounds such as fursulfamide;
Oxime ether compounds such as cyflufenamid;
Anthraquinone-based compounds such as dithianon;
Crotonic acid-based compounds such as meptyldinocap;
Antibiotics such as validamycin, kasugamycin, polyoxins;
Guanidine-based compounds such as iminoctadine and dodine;
Quinoline-based compounds such as tebufloquin and quinoxyfen;
Thiazolidine compounds such as flutianil;
Carbamate compounds such as propamocarb hydrochloride and tolprocarb Sulfur compounds such as sulfur;
Other compounds include pyribencarb (pyribencarb), isoprothiolane (isoprothiolane), pyroquilon (pyroquilon), diclomedine (diclomezine), chlorpicrin (chloropicrin), dazomet (dazomet), metham sodium (metam-sodium), metrafenone (metrafenone), Nikobifen (nicobifen), UBF-307, diclosymet (diclocymet), proquinazide (proquinazid), mandipropamide (mandipropamid), fluopicolide (fluopicolide), carpropamid (carpropamid), pyriophenone (pyriofenone), ferimmin, spiramine, spiramine, spiramine (Fenpyrazamine), amethoctrazine (ametoctradin), oxathiapiprolin (picathbutrazox), NK-1001, SB-4303, MIF-10 01, MIF-1002, BAF-1107, SYJ-247, NNF-0721, and the like.
Furthermore, it can be mixed with or used in combination with a microbial bactericide such as Bacillus amyloliqefaciens strain QST713, Bacillus amyloliqefaciens strain FZB24, Bacillus amyloliqefaciens strain MBI600, and Bacillus amyloliqefaciens strain D747.

Insecticides, acaricides, nematicides or soil pesticides among the above other pesticides, that is, the active ingredient compounds of the pesticides (generic names; including some applications, or Japan Plant Protection Association Test Code )
Profenofos, dichlorvos, fenamiphos, fenitrothion, EPN, diazinon, chlorpyrifos, chlorpyrifos-methyl, acephate, acephate, prothiophos Fosthiazate, cadusafos, disulfoton, isoxathion, isofenphos, ethion, etrimfos, quinalphos, dimethylvinphos, methinephos ), Sulprofos, thiometon, vamidothion, pyraclofos, pyridafenthion, pyrimiphos-methyl, pirimiphos-methyl Paphos (propaphos), hosalon (phosalone), formothion (formothion), malathion (malathion), tetrachlorvinphos (tetrachlorvinphos), chlorfenvinphos (chlorfenvinphos), cyanophos (cyanophos), trichlorfon (trichlorfon), methidathion (methidathion) , Phenthoate, ESP, azinphos-methyl, fenthion, heptenophos, methoxychlor, methoxychlor, parathion, phosphocarb, demeton-S-methyl (demeton-S-) methyl), monocrotophos, methamidophos, imicyafos, parathion-methyl, terbufos, phosphamidon, phosmet, phorate Organophosphate compounds such;
Carbaryl, propoxur, aldicarb, carbofuran, thiodicarb, methomyl, methomyl, oxamyl, oxamyl, ethiofencarb, pirimicarb, fenobucarb, fenobucarb Carbamates such as carbosulfan, benfuracarb, bendiocarb, bendiocarb, furathiocarb, furothiocarb, isoprocarb, isoprocarb, metolcarb, metolcarb, xylylcarb, XMC, fenothiocarb Compound;
Nereistoxin derivatives such as cartap, thiocyclam, bensultap, thiosultap-sodium;
Organochlorine compounds such as dicofol, tetradifon, endosulfan, dienochlor, dieldrin;
Organometallic compounds such as fenbutatin oxide and cyhexatin;
Fenvalerate, permethrin, cypermethrin, deltamethrin, deltamethrin, cyhalothrin, cyhalothrin, tefluthrin, tefluthrin, ethofenprox, flufenprox, cyfluthrin , Fenpropathrin, flucythrinate, fluvalinate, cycloprothrin, lambda-cyhalothrin, pyrethrins, esfenvalerate, tetramethrin (Tetramethrin), resmethrin (resmethrin), protrifenbute, bifenthrin (bifenthrin), zeta-cypermethrin (zeta-cypermethrin), acrinathrin (acrinathrin), alpha-cypermethet (Alpha-cypermethrin), allethrin (allethrin), gamma-cyhalothrin (gamma-cyhalothrin), theta-cypermethrin (theta-cypermethrin), tau-fluvalinate (tau-fluvalinate), tralomethrin (tralomethrin), profluthrin Pyrethroid compounds such as, beta-cypermethrin, beta-cyfluthrin, metofluthrin, phenothrin, flumethrin;
Diflubenzuron, diflubenzuron, chlorfluazuron, teflubenzuron, flufenoxuron, flufenoxuron, lufenuron, novalron, triflumuron, hexaflumuron, hexaflumuron, bisflumuron Benzoylurea-based compounds such as (bistrifluron), noviflumuron, fluazuron;
Juvenile hormone-like compounds such as methoprene, pyriproxyfen, fenoxycarb, diofenolan;
Pyridazinone compounds such as pyridaben;
Pyrazole compounds such as fenpyroximate, fipronil, tebufenpyrad, tebufenpyrad, ethiprole, tolfenpyrad, acetoprole, acetoprole, pyrafluprole and pyriprole;
Imidacloprid (imidacloprid), nitenpyram (nitenpyram), acetamiprid (acetamiprid), thiacloprid (thiacloprid), thiamethoxam (thiamethoxam), clothianidin (clothianidin), niginotefuran (nidinotefuran), dinotefuran (ninote nicotine) Nooid compounds;
Hydrazine compounds such as tebufenozide, methoxyfenozide, methoxyfenozide, chromafenozide, and halofenozide;
Pyridine compounds such as pyridalyl and flonicamid;
Cyclic ketoenol compounds such as spirodiclofen, spiromesifen, and spirotetramat;
Strobilurin-based compounds such as fluacrypyrim;
Pyrimidinamine-based compounds such as flufenerim;
Dinitro compounds;
Organic sulfur compounds such as malathion;
Urea compounds such as flufenoxuron;
Triazine-based compounds such as cyromazine;
Hydrazone-based compounds such as hydramethylnon;
Other compounds include buprofezin, hexythiazox, amitraz, chlordimeform, chlordimeform, silafluofen, triazamate, triazamate, pymetrozine, pyrimidifener, and chlorimifen. ), Indoxacarb, acequinocyl, ethoxazole, etoxazole, cyromazine, 1,3-dichloropropene (1,3-dichloropropene), diafenthiuron, benclothiaz , Bifenazate, propargite, clofentezine, metaflumizone, metaflumizone, flubendiamide, fluflundiamide, cyflumetofen, chlorantrani Prolol (chlorantraniliprole), cyantranililiprol (cyantraniliprole), cyenopyraphen (cyenopyrafen), pyrifluquinazone (pyrifluquinazone), fenazaquin (fenazaquin), amidoflumet (amidoflumet), sulfluramide (sulfluramid), hydramethylnon (hydramethylnon) meta , Sulfoxaflor, cypropene, fluensulfone, ryanodine, verbutin, and the like; and the like. Furthermore, Bacillus thuringiensis aizawai, Bacillus thuringiensis kurstaki, Bacillus thuringiensis israelensis, Bacillus thuringiensis japonensis, Bacillus thuringiensis tenebrionis or crystalline protein toxins produced by Bacillus thuringiensis, entomopathogenic filamentous fungi, entomopathogenic filamentous fungi, Microbial pesticides such as avermectin, emamectin benzoate, milbemectin, milbemycin, milbemycin, spinosad, ivermectin, ivermectin, lepimectin, DE-175, ectamectin ), Antibiotics such as emamectin, spinetoram and semi-synthetic antibiotics; natural products such as azadirachtin, rotenone; repellents such as deet; Mixed with , Can also be used in combination.

  It is known that the sulfamoyl compound of the present invention is treated for controlling various plant diseases. Therefore, the preparation of the present invention can be used for plants infected with or at risk of phytopathogenic bacteria, for example, grass crops (rice, wheat, barley, oat, rye, corn, etc.), cruciferous crops (cabbage, Chinese cabbage, Radish, turnip, broccoli, cauliflower, nabana, etc., asteraceous crops (lettuce, burdock, shungiku, etc.), solanaceous crops (potato, eggplant, tomato, peppers, etc.), cucumber crops (cucumber, pumpkin, melon, watermelon, etc.) ), Leek crops (leek, leek, rakkyo, garlic, etc.), Apiaceae crops (celery, carrot, parsley, etc.), lily crops (lily, tulip, asparagus, etc.), Polygonaceae (buckwheat, etc.), legumes Crops (soybeans, kidney beans, adzuki beans, etc.), Convolvulaceae (sweet potatoes, etc.), Acalyptaceous crops (spinach, sugar beet) ), Grape crops (grapes, etc.), rose crops (roses, strawberries, apples, pears, peaches, loquats, almonds, etc.) or citrus crops (citrus, lemons, oranges, etc.), for example, Phytophthora Spp. It has a controlling effect on diseases caused by phytopathogenic fungi such as genus Bacillus, Plasmodiophora, Picium, Rosellinia, Helicobasidium, Streptomyces. In addition, it has an effect of controlling viral diseases mediated by Olpidium spp., Polymixa spp., And Spongospora spp. In particular, it shows a high control effect on diseases caused by Phytophthora, Peronospora, Aphanomyces, Spongospora, Plasmodiophora and Picium.

  The preparations of the present invention include rice blast; rice sheath blight; wheat and other barley wilt; downy mildew of cruciferous vegetables, spinach, onion, pumpkin, soybeans, grapes, etc .; Diseases of pepper, pepper, watermelon, pumpkin, tobacco, tomato, strawberry, cucumber, etc .; dry rot of onion; brown rot of watermelon; carrot spot rot; Seedling blight of vegetables such as beans, lettuce, cucumber, tomato, cabbage, Chinese cabbage; Cabbage verticillium wilt; Chinese cabbage yellow blight; Brassicaceae root-knot disease; It shows a controlling effect on rot, melon necrotic leaf spot, sugar beet root disease, lettuce big vein disease and the like.

The present invention also relates to (a) a method for stabilizing an agricultural chemical formulation containing at least one sulfamoyl compound selected from cyazofamid and amisulbrom.
That is, the method is characterized in that (b) hymexazole and (c) at least one sulfonate selected from the group consisting of α-olefin sulfonate and a salt of naphthalenesulfonic acid formalin condensate are added. Thereby, (a) at least one sulfamoyl compound selected from cyazofamid and amisulbrom can be chemically stabilized. In particular, the decomposition of the sulfamoyl compound can be suppressed.

  The preferred form in the stabilizing method according to the present invention is the same as the preferred form in the agrochemical preparation described above, and among them, (a) at least one kind of sulfamoyl compound selected from cyazofamide and amisulbrom and (b) hymexazole The compounding ratio is usually 1: 300 to 300: 1, preferably 1: 100 to 100: 1, more preferably 1:10 to 10: 1 by weight, and the (a) sulfamoyl compound and (c) α -The mixing ratio with at least one sulfonic acid salt selected from the group consisting of olefin sulfonic acid or a salt thereof and naphthalene sulfonic acid formalin condensate or a salt thereof is usually from 1:50 to 50: 1 by weight. , Preferably 1:40 to 40: 1, more preferably 1:15 to 5: 1; the (b) himexazole and the (c) sulfo Mixing ratio of the acid salt, typically in a weight ratio of 1: 200 to 200: 1, preferably 1: 50 to 50: 1, more preferably 1: 2 to 30: 1.

Hereinafter, Examples, Test Examples, Formulation Examples, and Reference Examples according to the present invention are described, but these do not limit the present invention.
Example 1
(1) (a) 0.6 parts by weight of a pulverized cyazofamid drug substance (purity 95.1%, average particle diameter 13 μm) (2) (b) Himexazole drug substance (purity 99%) 4.1 parts by weight (3) (C) Solpol 5115 (trade name, α-olefinsulfonic acid sodium salt) 0.5 parts by weight (4) Perlite 10.0 parts by weight (5) Sodium sulfate 84.8 parts by weight The mixture was pulverized and mixed with a machine to obtain a powder.

Example 2
(1) (a) 0.6 parts by weight of a pulverized cyazofamid drug substance (purity: 95%, average particle diameter: 13 μm) (2) (b) Himexazole drug substance (purity: 99%) 4.1 parts by weight (3) ( c) Solpol 5115 (trade name, α-olefin sulfonic acid sodium salt) 5.0 parts by weight (4) Perlite 15.0 parts by weight (5) Sodium sulfate 75.3 parts by weight And pulverized and mixed to obtain a powder.

Example 3
(1) (a) Finely pulverized cyazofamid drug substance (purity 95%, average particle diameter 13 μm) 4.2 parts by weight (2) (b) Himexazole drug substance (purity 99%) 30.3 parts by weight (3) ( c) Solpol 5115 (trade name, α-olefin sulfonate sodium salt) 1.0 part by weight (4) Perlite 15.0 parts by weight (5) Sodium sulfate 49.5 parts by weight The above components were mixed and centrifuged and milled. The mixture was pulverized and mixed to obtain a wettable powder.

Example 4
(1) (a) Finely pulverized cyazofamid drug substance (purity 95%, average particle diameter 13 μm) 4.2 parts by weight (2) (b) Himexazole drug substance (purity 99%) 30.3 parts by weight (3) ( c) Solpol 5115 (trade name, α-olefinsulfonic acid sodium salt) 10.0 parts by weight (4) Perlite 10.0 parts by weight (5) Sodium sulfate 45.5 parts by weight The mixture was pulverized and mixed to obtain a wettable powder.

Example 5
(1) (a) Finely pulverized cyazofamid drug substance (purity 95%, average particle diameter 13 μm) 4.2 parts by weight (2) (b) Himexazole drug substance (purity 99%) 30.3 parts by weight (3) ( c) NK WG-2 (trade name, sodium salt of naphthalenesulfonic acid formalin condensate) 5.0 parts by weight (4) Perlite 15.0 parts by weight (5) Sodium sulfate 45.5 parts by weight The above components were mixed, The mixture was pulverized and mixed by a centrifugal pulverizer to obtain a wettable powder.

Example 6
(1) (a) Finely pulverized cyazofamid drug substance (purity 95%, average particle diameter 13 μm) 4.2 parts by weight (2) (b) Himexazole drug substance (purity 99%) 30.3 parts by weight (3) ( c) Tamol NN8906 (trade name, sodium salt of naphthalenesulfonic acid formalin condensate) 10.0 parts by weight (4) Perlite 10.0 parts by weight (5) Sodium sulfate 45.5 parts by weight The above components were mixed and centrifugally crushed. The mixture was ground and mixed to obtain a wettable powder.

Example 7
(1) (a) Cyazofamide bulk material (purity 95%, average particle size 13 μm) 4.2 parts by weight (2) (b) Himexazole bulk material (purity 99%) 30.3 parts by weight (3-1) (C) Solpol 5115 (trade name, sodium salt of α-olefin sulfonic acid) 0.5 parts by weight (3-2) (c) NK WG-2 (trade name, sodium salt of naphthalene sulfonic acid formalin condensate) 10 0.0 parts by weight (4) Perlite 15.0 parts by weight (5) Sodium sulfate 40.0 parts by weight The above components were mixed and pulverized and mixed by a centrifugal pulverizer to obtain a wettable powder.

Example 8
(1) (a) Cyazofamide bulk material (purity 95%, average particle size 13 μm) 4.2 parts by weight (2) (b) Himexazole bulk material (purity 99%) 30.3 parts by weight (3-1) (C) Sorpol 5115 (trade name, α-olefin sulfonic acid sodium salt) 1.0 part by weight (3-2) (c) NK WG-2 (trade name, sodium salt of naphthalene sulfonic acid formalin condensate) 10 0.0 parts by weight (4) Perlite 15.0 parts by weight (5) Sodium sulfate 39.5 parts by weight The above components were mixed and pulverized and mixed by a centrifugal pulverizer to obtain a wettable powder.

Example 9
(1) (a) Cyazofamide bulk material (purity 95%, average particle size 13 μm) 4.2 parts by weight (2) (b) Himexazole bulk material (purity 99%) 30.3 parts by weight (3-1) ) (C) Solpol 5115 (trade name, sodium salt of α-olefin sulfonic acid) 5.0 parts by weight (3-2) (c) NK WG-2 (trade name, sodium salt of naphthalene sulfonic acid formalin condensate) 30 0.0 parts by weight (4) Perlite 15.0 parts by weight (5) Sodium sulfate 15.5 parts by weight The above components were mixed and pulverized and mixed by a centrifugal pulverizer to obtain a wettable powder.

Example 10
(1) (a) Cyazofamide bulk material (purity 95%, average particle size 13 μm) 4.2 parts by weight (2) (b) Himexazole bulk material (purity 99%) 30.3 parts by weight (3-1) ) (C) Solpol 5115 (trade name, sodium salt of α-olefin sulfonic acid) 5.0 parts by weight (3-2) (c) NK WG-2 (trade name, sodium salt of naphthalene sulfonic acid formalin condensate) 45 5.5 parts by weight (4) perlite 15.0 parts by weight The above components were mixed and pulverized and mixed with a centrifugal pulverizer to obtain a wettable powder.

Reference Example 1
(1) (a) Cyazofamid bulk material (purity 95%, average particle size 13 μm) 0.6 parts by weight (4) Perlite 15.0 parts by weight (5) Sodium sulfate 84.4 parts by weight Then, the mixture was pulverized and mixed by a centrifugal pulverizer to obtain a powder.

Reference Example 2
(1) (a) 0.6 parts by weight of a finely divided cyazofamide bulk (purity 95%, average particle size 13 μm) (3) (c) Sorpol 5115 (trade name, sodium α-olefin sulfonate) 1.0 Parts by weight (4) 15.0 parts by weight of perlite (5) 83.4 parts by weight of sodium sulfate The above components were mixed and pulverized and mixed by a centrifugal pulverizer to obtain a powder.

Reference Example 3
(1) (a) 0.6 parts by weight of a pulverized cyazofamid drug substance (purity: 95%, average particle size: 13 μm) (2) (b) 4.1 parts by weight: hymexazole drug substance (purity: 99%) 4.1 parts by weight (4) Perlite 10.0 parts by weight (5) 85.3 parts by weight of sodium sulfate The above components were mixed and pulverized and mixed by a centrifugal pulverizer to obtain a powder.

Reference example 4
(1) (a) Pulverized cyazofamid drug substance (purity 95%, average particle diameter 13 μm) 4.2 parts by weight (2) (b) Himexazole drug substance (purity 99%) 30.3 parts by weight (3) Solpol 5050 (trade name, dialkyl sulfosuccinate sodium salt) 10.0 parts by weight (4) Perlite 10.0 parts by weight (5) Sodium sulfate 45.5 parts by weight The above components were mixed and crushed and mixed by a centrifugal crusher. , A wettable powder was obtained.

Reference Example 5
(1) (a) Finely ground cyazofamide substance (purity 95%, average particle size 13 μm) 4.2 parts by weight (2) (b) Himexazole substance (purity 99%) 30.3 parts by weight (3) Suprazil WP (trade name, dialkylnaphthalenesulfonic acid sodium salt) 5.0 parts by weight (4) Perlite 15.0 parts by weight (5) Sodium sulfate 45.5 parts by weight The above components were mixed and crushed and mixed by a centrifugal crusher. , A wettable powder was obtained.

Reference example 6
(1) (a) Pulverized cyazofamid drug substance (purity: 95%, average particle diameter: 13 μm) 4.2 parts by weight (2) (b) Himexazole drug substance (purity: 99%) 30.3 parts by weight (3) NK WG-4 (trade name, lignin sulfonic acid sodium salt) 5.0 parts by weight (4) Perlite 15.0 parts by weight (5) Sodium sulfate 45.5 parts by weight The above components were mixed and crushed and mixed by a centrifugal crusher. Then, a wettable powder was obtained.

Test example 1
The dusts obtained in Examples 1 and 2 and Reference Examples 1 to 3 were stored in a thermostat at 54 ° C. for 14 days. The content of cyazofamide in the powder before and after the lapse of time was quantified by high performance liquid chromatography, and the decomposition rate of each cyazofamide was calculated by the following formula, and the change with time was evaluated. Table 1 shows the results. In addition, in this specification, the number of each component in a table | surface is a content rate (weight%) immediately after manufacture.
Decomposition rate (%) = [(XY) / X] * 100
X: content immediately after production Y: content after storage

  As in Reference Example 2, the α-olefin sulfonate alone suppressed the decomposition of cyazofamide, but as in Examples 1 and 2, the combined use with himexazole significantly increased the decomposition suppression effect.

Test example 2
According to Test Example 1, the change over time of the wettable powders obtained in Examples 3 to 6 and Reference Examples 4 to 6 was evaluated. Table 2 shows the results.
Here, the sodium dialkylsulfosuccinate used in Reference Example 4 is a sulfonate in which decomposition of nitenpyram was suppressed in Examples 1 to 3 of Patent Document 3. The ligninsulfonic acid sodium salt used in Reference Example 6 is a compound described in Formulation Example 4 of Patent Document 1.

  In the sulfonic acid salt, as shown in Examples, the salt of α-olefin sulfonic acid salt and naltarene sulfonic acid formalin condensate remarkably suppressed the decomposition of cyazofamid, but the sulfonic acid salt shown in Reference Example was sufficient. No significant decomposition inhibiting effect was obtained.

Test example 3
According to Test Example 1, the change over time of the wettable powders obtained in Examples 7 to 10 was evaluated. Table 3 shows the results.

Formulation Example 1
(1) (a) 5.3 parts by weight of a pulverized cyazofamid drug substance (purity: 95%, average particle size: 13 μm) (2) (b) 0.5 part by weight of himexazole drug substance (purity: 99%) (3) ( c) NK WG-2 (trade name, sodium salt of naphthalenesulfonic acid formalin condensate) 20.0 parts by weight (4) 15.0 parts by weight of perlite (5) 59.2 parts by weight of sodium sulfate The mixture is pulverized and mixed by a centrifugal pulverizer to obtain a powder.

Formulation Example 2
(1) (a) 0.6 parts by weight of a pulverized cyazofamide substance (purity: 95%, average particle diameter: 13 μm) (2) (b) 50.0 parts by weight (3): Himexazole substance (purity: 99%) ) (C) Solpol 5115 (trade name, sodium salt of α-olefin sulfonic acid) 5.0 parts by weight (3-2) (c) NK WG-2 (trade name, sodium salt of naphthalene sulfonic acid formalin condensate) 15 0.0 parts by weight (4) Perlite 15.0 parts by weight (5) Sodium sulfate 14.4 parts by weight The above components were mixed and pulverized and mixed by a centrifugal pulverizer to obtain a wettable powder.

Formulation Example 3
(1) (a) 31.6 parts by weight of a pulverized cyazofamid drug substance (purity: 95%, average particle diameter: 13 μm) (2) (b) 5.1 parts by weight of a hymexazole drug substance (purity: 99%) (3-1) (C) Sorpol 5115 (trade name, α-olefin sulfonic acid sodium salt) 1.0 part by weight (3-2) (c) NK WG-2 (trade name, sodium salt of naphthalene sulfonic acid formalin condensate) 10 0.0 parts by weight (4) Perlite 10.0 parts by weight (5) Sodium sulfate 42.3 parts by weight The above components are mixed and pulverized and mixed with a centrifugal pulverizer to obtain a wettable powder.

Formulation Example 4
(1) (a) 1.1 parts by weight of a pulverized cyazofamid drug substance (purity: 95%, average particle size: 13 μm) (2) (b) 80.8 parts by weight (3-1): Himexazole drug substance (purity: 99%) ) (C) Sorpol 5115 (trade name, α-olefin sulfonic acid sodium salt) 5.0 parts by weight (3-2) (c) NK WG-2 (trade name, naphthalene sulfonic acid formalin condensate sodium salt) 10 0.0 parts by weight (5) Sodium sulfate 3.1 parts by weight The above components are mixed and pulverized and mixed by a centrifugal pulverizer to obtain a wettable powder.

Formulation Example 5
(1) (a) Finely pulverized cyazofamid drug substance (purity: 95%, average particle diameter: 13 μm) 5.3 parts by weight (2) (b) Himexazole drug substance (purity: 99%) 5.1 parts by weight (3) ( c) Solpol 5115 (trade name, α-olefin sulfonate sodium salt) 5.0 parts by weight (4) Bentonite 20.0 parts by weight (5) Clay 64.6 parts by weight The above components were mixed and centrifuged with a centrifugal mill. After pulverization and mixing, an appropriate amount of water is added and kneaded, granulated, and dried to obtain granules.

Formulation Example 6
(1) (a) Cyazofamide bulk material (purity 95%, average particle size 13 μm) 4.2 parts by weight (2) (b) Himexazole bulk material (purity 99%) 30.3 parts by weight (3-1) ) (C) Sorpol 5115 (trade name, α-olefin sulfonic acid sodium salt) 5.0 parts by weight (3-2) (c) NK WG-2 (trade name, naphthalene sulfonic acid formalin condensate sodium salt) 10 0.0 parts by weight (4) Bentonite 10.0 parts by weight (5) Sodium sulfate 40.5 parts by weight After mixing the above components, pulverizing and mixing with a centrifugal pulverizer, adding an appropriate amount of water, kneading, granulating, Dry to obtain a wettable powder.

Formulation Example 7
(1) (a) 5.3 mg by weight of amisulbromide (purity: 95%) (2) (b) 0.5 part by weight of himexazole (purity: 99%) (3) (c) NK WG-2 (product) Name, sodium salt of naphthalenesulfonic acid formalin condensate) 20.0 parts by weight (4) 15.0 parts by weight of perlite (5) 59.2 parts by weight of sodium sulfate The above components were mixed and crushed and mixed by a centrifugal crusher. , Get a powder.

Formulation Example 8
(1) (a) 0.6% by weight of an amisulbromine drug substance (purity: 95%) (2) (b) 50.0 parts by weight of a himexazole drug substance (purity: 99%) (3-1) (c) Solpol 5115 (product) Name, α-olefinsulfonic acid sodium salt) 5.0 parts by weight (3-2) (c) NK WG-2 (trade name, sodium salt of naphthalenesulfonic acid formalin condensate) 15.0 parts by weight (4) perlite 15.0 parts by weight (5) Sodium sulfate 14.4 parts by weight The above components are mixed and pulverized and mixed by a centrifugal pulverizer to obtain a wettable powder.

Although the present invention has been described in detail and with reference to specific embodiments, it will be apparent to those skilled in the art that various changes and modifications can be made without departing from the spirit and scope of the invention.
This application is based on Japanese Patent Application (No. 2014-218200) filed on Oct. 27, 2014, the contents of which are incorporated herein by reference.

Claims (14)

A pesticide formulation containing (a) cyazofamid, (b) hymexazole, and (c) at least one sulfonate selected from the group consisting of salts of α-olefin sulfonate and naphthalenesulfonic acid formalin condensate. The agricultural chemical formulation according to claim 1, wherein the (a) cyazofamid and the (b) himexazole are contained in a weight ratio of 1: 100 to 100: 1. The agricultural chemical formulation according to claim 1 or 2, wherein the (a) cyazofamid and the (b) himexazole are contained at a weight ratio of 1:10 to 10: 1. The agricultural chemical formulation according to any one of claims 1 to 3, wherein the (a) cyazofamid and the (c) sulfonate are contained at a weight ratio of 1:40 to 40: 1. The agricultural chemical formulation according to any one of claims 1 to 4, wherein the (a) cyazofamid and the (c) sulfonate are contained at a weight ratio of 1:15 to 5: 1. Based on the total amount of the preparation, (a) 0.3 to 90% by weight of cyazofamide, (b) 0.3 to 90% by weight of himexazole, and (c) 0.1 to 60% by weight of sulfonate. The agricultural chemical formulation according to any one of claims 1 to 5, which contains the agricultural chemical.   The agricultural chemical formulation according to any one of claims 1 to 6, wherein the formulation is a solid preparation.   The agricultural chemical formulation according to claim 7, wherein the solid preparation is a wettable powder, a powder, a wettable powder, a granule, or a water-soluble pack. (B) hymexazole and (c) at least one sulfonate selected from the group consisting of a salt of an α-olefin sulfonate and a salt of a naphthalenesulfonic acid formalin condensate ; A method for stabilizing a pesticide formulation containing: The stabilization method according to claim 9, wherein the decomposition of the (a) cyazofamide is suppressed by adding the (b) hymexazole and the (c) sulfonate. The compounding ratio of the (a) cyazofamide and the (b) himexazole is 1: 100 to 100: 1 by weight, and the compounding ratio of the (a) cyazofamide and the (c) sulfonate is a weight ratio. The stabilization according to claim 9 or 10, wherein the compounding ratio of the (b) hymexazole and the (c) sulfonate is 1:50 to 50: 1 by weight, and the compounding ratio of the (b) himexazole to the (c) sulfonate is 1:50 to 50: 1. Method. The compounding ratio of the (a) cyazofamide and the (b) himexazole is 1:10 to 10: 1 by weight, and the compounding ratio of the (a) cyazofamide and the (c) sulfonate is a weight ratio. 12. The compound according to any one of claims 9 to 11, wherein the compounding ratio of the (b) hymexazole and the (c) sulfonate is 1: 2 to 30: 1 by weight. The method of stabilization described in 1. The stabilization method according to any one of claims 10 to 12, wherein the preparation is a solid preparation, and the decomposition of the (a) cyazofamid is suppressed in the solid preparation.   14. The method according to claim 13, wherein the solid preparation is a wettable powder, a powder, a wettable powder, a granule, or a water-soluble pack.