JP6630980B2 - Health management device and health management method - Google Patents

Description

The present invention measures the information of a living body, particularly a living body related to the circulatory system such as the heart, and can perform non-medical personnel without performing advanced detailed examinations and specialized medical examinations as conventionally performed in hospitals. Even related to the provision of a health management device and a health management method that can determine the health state of the living body, more specifically, a non-medical person determines the health state of the living body to be measured using the health management device, and as a result To provide a portable health management device and a health management method that are useful for making a decision to consult a specialized medical institution.
The present invention is firstly applied to a case where the living body to be measured is a human and exerts a great effect, but can also be applied to a case where the living body to be measured is not a human.
However, a particularly important purpose is utilization to humans, and in the following description, a case where a living body to be measured is a human will be described as an example.
Furthermore, the present invention contributes to the enhancement of wearable devices.

  In recent years, medical progress has been remarkable, and the causes of diseases that have so far made progress that seemed to be independent in each specialty are sometimes caused by different medical fields, which are considered to have different medical specialties. It has been reported that phenomena are responsible for the disease.

  Such reports often attract the interest of the viewers of the report and often become a barometer of the popularity of the report.

  However, the judgment of the relationship between the medical phenomena in a plurality of different fields, which are considered to have different medical specialties reported as the cause of the disease and the cause of the disease, has been conventionally performed in hospitals and the like. It may include estimates from some advanced workups or specialized consultations, and may not be officially recognized by the medical community.

  As a result, in addition to various circumstances, there may be strong criticism from a particular medical specialty, and the situation may develop into an excuse for the report.

  On the other hand, there is concern that insurance costs will rise from the viewpoint of medical administration and medicine, including pharmaceuticals, and not only will they rely on specialized medical institutions, but also expect non-medical personnel to maintain their health. I have.

  Also, in recent years, there has been a feeling that the topic of wearable devices has been increasing, mainly in the electronic equipment industry. As a part of a wearable device, the inventors who are developing medical technology are expected to realize a health management device that enables even non-medical persons to judge the health of a living body.

Electronic devices that can be considered as medical devices used by non-medical persons currently known include a wristwatch-type pulse meter and a blood pressure monitor that measures pressure by wrapping a cuff around the arm and applying pressure to the arm. . In the example of the pulsimeter, generally, the number of electrical pulses of the heart is measured, and the number of pulses for several seconds or an average value for a predetermined time is obtained and displayed as a heart rate . In the example of the blood pressure monitor, generally, the pressure applied to the cuff is continuously increased from a low pressure while detecting the pulse sound of the blood flow flowing through the arm with a sensor, and the pressure is reduced when the pressure is increased to a target value. , The systolic blood pressure (systolic blood pressure) and the diastolic blood pressure (diastolic blood pressure) are measured, determined as normal blood pressure, abnormal blood pressure, and the like, and displayed.

  The sphygmomanometer of Patent Literature 1 and the pulsimeter of Patent Literature 2 detect a pulse wave of blood sent from the heart to the whole body, process the respective processing circuits, and output blood pressure information and pulse information, respectively.

  Patent Literature 1 describes that there are a method of measuring blood pressure using a cuff and a method of measuring blood pressure without using a cuff as a method of measuring blood pressure. A method of measuring blood pressure by changing the pressure of a mounting portion using a cuff mounted on an arm has been used in clinical practice for many years, and its accuracy has been recognized by society. The main method of measuring blood pressure without using a cuff is to provide a pulse wave sensor on the heart side and the apical side, measure the pulse wave propagation time, and calculate the blood pressure. However, although the method of measuring blood pressure without using a cuff uses a plurality of sensors, there are advantages that the size can be reduced and the degree of restraint of the subject is low. It is also described that there is a problem that the blood pressure cannot be accurately measured due to mental stress or the like, because the blood vessel properties are changed only depending on the principle.

  Patent Literature 1 describes that a state in which blood vessel properties change independently of blood pressure due to mental stress or the like and hinders accurate blood pressure measurement is alleviated. The R wave of the cardiac potential waveform is detected, and the pulse wave on the artery is detected in synchronization with the pulse wave detected by the fingertip photoelectric pulse wave sensor, and the parameters related to the vascular properties are calculated and reflected in the blood pressure measurement. .

  Patent Literature 2 describes that a pulse wave of a human wrist is measured using a photoelectric sensor attached to a portable timepiece to calculate a pulse rate. Based on the medical recognition that arteries obey the blood vessel method, it measures pulse wave fluctuations when pressure is applied to blood vessels and describes changes in waveforms when examining wearing conditions .

  However, patent documents relating to a sphygmomanometer and a pulsimeter, including Patent Documents 1 and 2, disclose a measurement result and a rough change in a waveform change when a pulse wave has a maximum value, a minimum value, or pressure. Is described, but nothing is described except for the blood pressure and pulse values related to human health, and it relates to the intensity change of the movement of one heartbeat of the heart and health conditions such as diseases. No description found.

  Patent Literature 3 and Patent Literature 4 are patent documents by the present inventor and mainly describe estimation of a human disease using an apical pulsation diagram exemplified by measurement using a pressure sensor. In these documents, an apical pulsation diagram of a healthy person or a patient diagnosed based on a conventional diagnostic method other than the present invention or a patient diagnosed as having a specific disease is measured. It is described that an algorithm capable of determining whether the subject is a healthy person or a sick person was created using the measured apex pulsation diagram.

  However, in order to apply Patent Documents 3 and 4 to a wearable device, how to relate to the human body is important, but there is almost no specific description of this portion.

JP-A-8-140948 JP 2013-212320 A JP 2008-113728 A JP 2009-273817 A

  The present invention has been made in view of the above circumstances. The problem to be solved by the present invention is to provide a portable health management device and a health management method at low cost, which clarify how a sensor that can be used as a wearable device relates to a human body.

Another object of the present invention is to provide a wearable product using a sensor at low cost.

  A remarkable feature of the technical idea of the present invention made in order to solve the above-mentioned problem is that it is possible to recognize the individual differences of the heart and to more accurately determine the health condition of the living body to be measured as much as possible. It is in.

  A first invention (hereinafter also referred to as invention 1) as an example of the present invention made to solve the problem includes at least one of a pressure change, a change in a wave reflection state, and a change in an electric field and / or a magnetic field. In the apical pulsation diagram of a living body created as a detection sensor for detecting the apical pulsation diagram, when the abscissa is represented by orthogonal coordinate axes with the ordinate representing the detection value axis and the abscissa representing the time axis, the time axis of the heart A health management device characterized in that a health condition of a measured living body is determined by multiplying a correction coefficient only during a systole period.

  A second invention (hereinafter also referred to as invention 2) as an example of the present invention made to solve the problem includes at least one of a change in pressure, a change in a reflection state of a wave, and a change in an electric field and / or a magnetic field. Characteristic point P (2) in an apical pulsation diagram of a living body created as a detection sensor for detecting a point, where the abscissa pulsation diagram is represented by orthogonal coordinate axes with the vertical axis representing the detection value axis and the horizontal axis representing the time axis. A health management device characterized in that a health condition of a living body to be measured is determined by multiplying a correction coefficient only on a time axis between P and (6).

  A third invention (hereinafter referred to as Invention 3) as an example of the present invention developed by developing Invention 1 or 2 is a health management device according to Invention 1 or 2, wherein the heart rate of the living body to be measured is V. The health care device is characterized in that the correction coefficient by which the time axis is multiplied by ΔV / 60, which means the square root of V / 60, is used.

  A fourth invention (hereinafter also referred to as invention 4) as an example of the present invention made to solve the problem includes at least one of a change in pressure, a change in a reflection state of a wave, and a change in an electric field and / or a magnetic field. In the apical pulsation diagram of a living body created as a detection sensor for detecting the apex, when the apical pulsation diagram is represented by orthogonal coordinate axes in which the vertical axis is the detection value axis and the horizontal axis is the time axis, the apex for determining the health state The time axis is corrected so that the feature points P (2) and the feature points P (6) of the apical pulsation chart to be referred to for the pulsation chart and the determination are used to determine the health state of the living body to be measured. A health management device characterized by the following.

  A fifth invention (hereinafter, referred to as invention 5) as an example of the present invention developed by developing inventions 1 to 4 is the health management device according to any one of inventions 1 to 4, wherein the detection sensor is A health management device characterized by being a fibrous sensor.

  A sixth invention (hereinafter referred to as invention 6) as an example of the present invention developed by developing invention 5 is characterized in that, in the health management device according to invention 5, the detection sensor is a piezoelectric fiber. It is a health management device.

  A seventh invention (hereinafter referred to as Invention 7) as an example of the present invention developed by developing Invention 5 or 6 is the health management device according to Invention 5 or 6, wherein the detection sensor is a plurality of the fibrous forms. A health care device characterized by a structure in which the sensors are knitted in different directions.

  An eighth invention (hereinafter, referred to as invention 8) as an example of the present invention made by developing inventions 5 to 7 is the health management device according to any one of inventions 5 to 7, wherein the detection sensor The health management device is characterized in that the at least one sensor is a sensor formed by winding at least one sensor having a smaller diameter around the sensor.

  A ninth invention (hereinafter referred to as invention 9) as an example of the present invention developed by developing inventions 5 to 8 is the health management device according to any one of inventions 5 to 8, wherein at least one of the sensor devices is provided. A health management device characterized in that a part of a fiber-like detection sensor and a normal fiber having no sensor function are configured in a blended state.

  A tenth invention (hereinafter referred to as invention 10) as an example of the present invention developed by developing invention 9 is the health management device according to invention 9, wherein the fibrous detection sensor configured in the mixed spinning state comprises: The health care device is characterized in that the conductor for voltage output does not lose electrical continuity.

  An eleventh invention (hereinafter referred to as invention 11) as an example of the present invention developed by developing inventions 5 to 10 is the health management device according to any one of inventions 5 to 10, wherein the fibrous state detection is performed. A health management device characterized in that a sensor is subjected to a moisture-proof treatment.

  A twelfth invention (hereinafter referred to as invention 12) as an example of the present invention developed by developing invention 11 is that in the health management device according to invention 11, the moisture-proof treatment includes application of a water-repellent substance. It is a health management device characterized by the following.

  A thirteenth invention (hereinafter referred to as invention 13) as an example of the present invention developed from invention 11 or 12 is a moisture-proof treatment applied to the sensor or around the sensor in the health management device according to invention 11 or 12. A health care device characterized in that the agent contains particles having a diameter of 200 nanometers or less.

A fourteenth invention (hereinafter referred to as invention 14) as an example of the present invention developed from inventions 1 to 13 is the health management device according to any one of inventions 1 to 13, wherein the sensor is provided with the sensor. The health management device is characterized in that the means to be attached to the measurement living body is means utilizing suction force.

A fifteenth invention (hereinafter referred to as invention 15) as an example of the present invention developed by developing inventions 1 to 14 is the health management device according to any one of inventions 1 to 14, wherein A predetermined time before a position (hereinafter referred to as a QRS peak position) on the apex pulsation waveform corresponding to each QRS-positive peak value of the electrocardiogram at the same time, that is, the R wave, the predetermined time from the next QRS peak position The previous cardiac pulsation diagram waveform is defined as a unit waveform. In the unit waveform, when the lowest point C1 on the cardiac pulsation diagram waveform exists at the QRS peak position ± 30 ms (millisecond), the minimum point C1 is defined as a feature point P (2). ), If C1 is unclear, the QRS peak position of the apex pulsation waveform is taken as the feature point P (2), and the peak on the apex pulsation waveform within 160 ms before the QRS peak position. Positive vertex exists If the positive peak is not found in the apex pulsatile waveform within 160 ms before the QRS peak position, the QRS peak of the apical pulsatile waveform is detected. If the position is a feature point P (1), and a positive vertex of the apex pulsatile waveform is temporally 50 to 150 ms after the feature point P (2), it is defined as a feature point P (3), and a heart sound chart is obtained. If there is a positive vertex between the 2A sound that is the aortic closing sound of the above and less than 60 ms before the positive vertex, the positive vertex closest to the position corresponding to the 2A sound in the apex pulsation waveform is the feature point P (5). If the feature point P (5) is temporally less than 40 ms before the position corresponding to the 2A sound on the apex pulsatile waveform, it is defined as a feature point P ′ (5), If the feature point P (5) is at a position corresponding to the 2A sound in the apex pulsatile waveform If it is temporally before 40 ms to less than 50 ms, it is set as a feature point P ″ (5), and if the feature point P (5) is located at a position corresponding to the 2A sound in the apex pulsatile waveform, From 50 ms to less than 60 ms before, it is regarded as a feature point P ′ ″ (5), and each of the feature points P ′ (5), P ″ (5), P ″ Unless it is necessary to express the deviation of '(5) in a distinctive manner, it refers to any of the feature points P' (5), P '' (5), P '''(5) When expressed generically, the characteristic point P (5) is simply referred to as the characteristic point P (5). The characteristic point P (3) does not exist on the apex pulsation waveform, and the characteristic point P (5) as a generic name is used. ) Does not exist, the apex pulsatile waveform that is 150 ms temporally after the feature point P (2) and 60 ms or more temporally before the 2A sound is positive. When an extreme value exists, the feature point is defined as a feature point P (4). When a negative extreme value of the apex pulsation waveform exists 50 to 150 ms later from the 2A sound, it is defined as a feature point P (6). When the time between 100 and 240 ms after the sound 2A and the feature point P (6) is present, and the positive extreme value of the apical pulsation waveform exists after the feature point P (6) Makes it the characteristic point P (7), and temporally after the characteristic point P (7) and temporally before the characteristic point P (1) of the next unit waveform. If a positive extreme value exists, it is called a feature point P (8), and the feature points P (1), P (2), P (3), P (4), P (5), P ′ (5), P ″ (5), P ″ ′ (5), P (6), P (7), P (8) as a first feature point group, and feature points of an apex pulsation waveform With P (1) as the positive vertex, , The waveform portion rising on the apex pulsation diagram is defined as A wave, the position of the positive peak value of the A wave in the first derivative waveform of the apex pulsation diagram is defined as point a, and the positive extreme value rising from P (2). , The position of the positive peak value of the E wave in the first derivative waveform of the apex pulsation diagram is point e, the ascending wave portion rising from P (6) is the F wave, The position of the positive peak value of the F wave in the first derivative waveform of the pulsation diagram is point f, and the heights of the points a, e, and f, that is, the heights of the vertical axes are a, e, and f, respectively. ,
The first feature point determination means is a determination means for determining the presence / absence of at least two feature points in the first feature point group, and the second feature point determination means is defined as a vertical axis of the unit waveform. Determination of determining the height of at least one of P (1), P (2), and P (7) when the minimum vertical axis coordinate is 0 point and the maximum vertical axis coordinate is 1000 points. As a means, the third feature point determination means is configured to perform a P (2) -P (3) time between the feature points, that is, a time from P (2) to P (3) (hereinafter the same), P (6) -P (7) time, 2-P (6) time, that is, time from 2A sound to P (6) (the same applies hereinafter), 2-P (7) time, P (3) -P (5) A determination means for determining at least one of magnitudes by using a ratio of time to P (2) -P (6) time as a feature index,
The first waveform judging means is compared with a waveform judging pattern built in the health care device of the present invention or an apex rhythm chart inputted to the health care device of the present invention from the outside of the health care device, and a unit waveform portion is compared. The second waveform determining means as the determining means for determining the values of a, e, and f, and the third waveform determining means as the apical pulsation waveform Is a determining means for determining whether or not there is a section in which the differential waveform can be determined to be substantially horizontal as the tendency in the vicinity of the differential value between the point e and the lowest point immediately before the point f of the primary differential waveform, The fourth waveform determining means determines that the position of the lowest point immediately before the point f of the first derivative waveform of the apex pulsatile waveform is the point where the differential value immediately before the lowest point is zero and the position immediately after the lowest point is To determine whether the derivative of is located in the first half between the zero point The fifth waveform determination means determines whether the measured apical pulsation chart is a unimodal graph having P (3) and no P (5). In the case of the unimodal graph, , When the height of P (3) is normalized to 1000 points, the width of the graph at 700 points is less than 100 ms in a part temporally behind P (3), which is defined as a half width after P (3). The sixth waveform determining means determines the characteristic of the primary differential waveform between the time corresponding to the 2A sound in the primary differential waveform of the apex pulsation waveform and the vicinity of P (6). When extracted and used as determination means for determining the health state of the measured living body from its characteristics,
The evaluation means in the health management device of the present invention evaluates the health condition of the living body to be measured using the data processing result of the data processing means, and evaluates the first to third feature point determination means and the first to third characteristic points. A health management device comprising at least one of the nine determination means of the sixth waveform determination means.

  A sixteenth invention as an example of the present invention (hereinafter, also referred to as invention 16) made to solve the problem uses a health management device according to any one of inventions 1 to 15 to measure a living body to be measured. A health management method characterized by judging a health condition of a subject.

  Although the apical pulsation chart has been recognized as medically important in the past, the equipment is not custom-made, the measurement has extremely high medical expertise, and the user understands the use of the apical pulsation chart. It was a diagnosis of a circulatory organ that could not be measured or utilized with very few specialists. According to the present invention, it can be widely used by the general public by developing a measurement system that can measure not only medical professionals but also non-medical professionals and ordinary people, and developing algorithms that can be applied to the health management of the living body to be measured based on the measurement results. The use of a health management system was made possible. As a result, early detection of the disease of the subject, appropriate determination of whether to go to a hospital or the like where there are many medical professionals, and reduction of medical expenses have been realized. As a result, it has made it possible to drastically reduce the cost of National Health Insurance and paved the way for more appropriate use of medical expenses.

It is sectional drawing which image | photographed the human breast as a to-be-measured body by MRI. It is sectional drawing which image | photographed the human breast as a to-be-measured body by MRI. It is a figure which illustrates a heart typically. It is a figure which illustrates a heart typically. It is a schematic diagram explaining the positional relationship of a left ventricle, a left atrium, and an aorta. It is a schematic diagram explaining the motion of the whole heart. It is a schematic diagram explaining the end systole of a heart. It is a schematic diagram explaining an end diastole. It is sectional drawing of the example of the sensor apparatus used in embodiment of this invention. FIG. 10 is a schematic diagram of an example in which the sensor device of FIG. 9 is used for a living body. It is a schematic diagram which applied the sensor device of the present invention to the chest of the living body to be measured. It is an example of the apex pulsation diagram of the measured living body measured by the sensor device. It is an example of the apex pulsation diagram of the measured living body measured by the sensor device. It is an example of the apex pulsation diagram of the measured living body measured by the sensor device. It is a figure explaining an example of a display of a portable health management device of the present invention. It is a figure explaining the example which judges the health condition of a measured living body. It is a figure explaining the example which judges the health condition of a measured living body. It is a figure explaining the example which judges the health condition of a measured living body. It is a figure explaining the example which judges the health condition of a measured living body. It is a device that wraps around the chest and measures the apex rhythm. It is a figure explaining the example of a notch. It is a figure explaining the example of a notch. It is a figure explaining the example of a notch.

3, 11, 21: Electrocardiogram 4, 12, 22: Heart sound chart 5, 13, 23, 187, 197, A to D: Apical pulsation chart 6, 16, 25: One sound of heart sound chart 7, 17, 26: Two sounds of heart sound chart 10A, 18, 20A, 27: Notch 14, 24, 188: Primary differential waveform of apical pulsation chart 14a: Zero point of temporally preceding differential value of lowest point 4b 14b: Apical pulsation The lowest point of the primary differential waveform in the figure 14c: Zero point of the differential value temporally after the lowest point 4b 14d: Line with a differential value of 0 185, 195: ECG 185a, 195a: R wave of QRS wave of electrocardiogram 186 , 196: heart chart 186b, 196b: 2A sound of heart chart 250: thoracic vertebra 251: sternum 260: sensor device 260a: outer coating of sensor device 260b: inner coating of sensor device 260c, 260d: sensor body 260e: sensor holder Body 261A～261v: sensor body 262A～262f: sensor body 265: Chest epidermis 266: chest skin subcutaneous tissue 267,267A～267d: rib 268: left ventricular (LV)
269: right ventricle (right ventricle)
271: Left atrium (left atrium)
272: mitral valve 273: aortic valve 274: aorta 1010, 1011, 1012, F: arrow 1014: end-diastole of the heart 1015: end-systole of the heart 2701: apex (point of left ventricle)
P (1) to P (8), P (1) S to P (8) S, a, e, f: feature points

  Hereinafter, embodiments of the present invention will be described with reference to the drawings. Each drawing used in the description schematically shows the size, shape, arrangement relationship, and the like of each component so that the example of the present invention can be understood. For convenience of description of the present invention, the magnification may be partially changed in the drawings, and the drawings used in the description of the examples of the present invention may not necessarily be similar to the real thing or description of the embodiment. Also, in each of the drawings, the same components are denoted by the same reference numerals, and redundant description may be omitted.

  1 and 2 are cross-sectional views of a human chest as an object to be measured taken by MRI. FIG. 1 is taken in a supine position, and FIG. 2 is taken in a left lateral position. Reference numeral 250 indicates a thoracic vertebra, 265 indicates a thoracic epidermis of a living body to be measured, 267 indicates a rib, 268 indicates a left ventricle (hereinafter, also referred to as a left ventricle), 269 indicates a right ventricle (hereinafter, also referred to as a right ventricle), and 2701 indicates an apex (that is, apex). , The tip of the left ventricle).

  1 and 2 are MRI images of the same person. In FIG. 2 photographed in the left lateral position than in FIG. 1 photographed in the supine position, the apex 2701 is closer to the chest wall, that is, the chest epidermis 265. You can see that.

  FIG. 3 and FIG. 4 are diagrams schematically illustrating the heart based on the results of FIG. 1 and FIG. Reference numeral 271 denotes a left atrium (hereinafter, also referred to as left atrium), and 274 denotes an aorta. FIG. 3 is a diagram showing the positional relationship between the apex, the left ventricle, the left atrium, and the aorta, with the thoracic spine 250 on the right and the sternum 251 on the left. FIG. 4 is a diagram showing the arrangement of the right ventricle, the left ventricle, and the apex arranged inside the rib 267, omitting other organs.

  FIG. 5 is a schematic diagram illustrating the positional relationship between the left ventricle, the left atrium, and the aorta. Reference numeral 272 is a mitral valve, and 273 is an aortic valve.

FIG. 6 is a schematic diagram illustrating the movement of the entire heart 1013 (mainly, the left and right ventricles). Reference numerals 1010 and 1011 denote arrows for explaining the movement of the heart, and 1012 denotes arrows for explaining an example of the movement of the apex. The human heart repeats a contracting movement that narrows the rag. More specifically, when looking up at the entire heart from below, a systolic when apex is rotated in the arrow 1011 direction, i.e. counterclockwise direction, cardiac base is rotated in the arrow 1010 direction, i.e. clockwise same time. This reverse bouncing movement that follows is diastole, and the heart repeats this movement. During the systole, blood is pumped from the heart to the whole body. FIG. 7 is a schematic diagram illustrating the end-systole (reference numeral 1015) of the heart, and FIG. 8 is a schematic diagram illustrating the end-diastole (reference numeral 1014).

  FIG. 9 is a sectional view of an example of the sensor device used in the embodiment of the present invention. Reference numeral 260 denotes the sensor device, 260a denotes the outer coating of the sensor device, that is, the coating on the side opposite to the side facing the living body to be measured, 260b denotes the inner coating of the sensor device, that is, the side facing the living body to be measured, and 260c and 260d denote the same. A sensor meat portion surrounding the sensor of the device (that is, a portion excluding the sensor main body and its attached portion inside the sensor device is referred to as a meat portion), 260c is a sensor outer meat portion, and 260d is a sensor inner meat portion. , 261a to 261 are sensor bodies.

  Preferably, the inner coating 260b of the sensor device is less rigid than the outer coating 260a of the sensor device.

  Further, the sensor meat portion 260c and the sensor meat portion 260d can be made of the same material. However, the rigidity of the sensor meat portion 260c can be configured to be greater than the rigidity of the sensor meat portion 260d by changing the material or structure.

  Alternatively, the lubricating property of the sensor meat part 260c can be configured to be lower than the lubricity of the sensor meat part 260d. As an example, the sensor meat portion 260c can be made of an elastic resin, and the sensor meat portion 260d can be made of a lubricant. In this case, it is preferable that the resin and the lubricant are not mixed irreversibly.

  One particularly preferred example is that the inner coating 260b is formed of a soft material such as cloth. The sensor device is preferably configured such that the sensor body can move integrally with the inner coating 260b of the sensor device. With this configuration, for example, the sensor device is pressed against the skin of the living body to be measured from the outside of the outer coating 260a of the sensor device, or the inner coating 260b of the sensor device is placed inside the skin of the living body to be measured inside the sensor device. When the inner covering 260b is inserted between the ribs of the living body to be measured by applying a pressing force to the inner body 260b, the sensor body is also easily inserted between the ribs together with the inner covering 260b, and the movement of the apex 2701 is easily detected. Beat detection reliability can be improved. As an example of such a configuration, the sensor main body is bonded to the inner coating 260b, sewn with a thread or the like, or the sensor main body is arranged between the inner coating 260b and the coating (not shown) inside the inner coating 260b. And many other variations. Alternatively, a force such as a gas or a liquid can be used to exert a force on the inner coating 260b to press the inner coating 260b against the epidermis of the living body to be measured with which the inner coating 260b abuts.

  It is preferable that the inner coating 260b can be easily inserted between the adjacent ribs when an external force is applied to the outer coating 260a or when a force is applied to the inner coating 260b by some means. And it is preferable that the sensor main body near the inner coating 260b can enter into the vicinity of the inner coating 260b inserted between the adjacent ribs. More preferably, for example, when the sensor device 260 is used as shown in the example of FIG. 11 described later, when some force is applied to the outer coating 260a, the pressure is transmitted, so that the inner coating is formed. The sensor device 260 is positioned so that the sensor body 260 adjacent thereto can enter with the inner sheath 260b such that the proximal sensor body 260b approaches the proximal apex so as to partially penetrate between adjacent ribs adjacent thereto. It is preferable to configure.

  When, for example, a fibrous material is used as the material of the pressure-sensitive sensor of the sensor main body, at least a part of the sensor main body can be in the form of a cloth by utilizing the flexibility of the fibrous material. For example, when a fibrous pressure-sensitive sensor is used as an example of a material for the pressure-sensitive sensor of the sensor body while maintaining the necessary electrical insulation, a material that generates a positive or negative voltage in the sensor material due to pressure is used. Can be. In such a case, it is necessary to collect the positive and negative electricity generated by the displacement and to take it out. When a fibrous sensor is used, the fibrous sensor and a normal fiber having no sensor function are configured in a mixed state and / or a mixed spinning state as long as the continuity of the conductive portion of one fibrous sensor is not lost. Thus, a robust and highly reliable sensor can be configured.

  In the case of a non-conductive linear structure sensor body, as a means for extracting positive and negative voltages, for example, a conductor part capable of extracting one voltage is provided at the center of the sensor main body or at a position close to the center. A conductor portion from which the other voltage can be taken out is provided on the surface or a portion close to the outer surface of the sensor main body, and can be a part of the sensor output section of the pressure-sensitive sensor main body. In accordance with the movement of the apex, it can be detected as a voltage signal in which one becomes relatively positive and the other becomes negative.

  As a preferred example, the conductor provided at the center or near the center of the sensor main body is preferably in a linear form, and the conductor provided at the outer surface of the sensor main body or the portion near the outer surface of the sensor main body has at least a part thereof. A foil form is preferred.

  Further, the material of the sensor main body may lower the pressure detection sensitivity due to moisture. When such a sensor is attached to human skin and used, moisture-proof measures may be required.

  As an example of the moisture proof measure, there is a method in which a water repellent substance is mixed with a moisture proofing agent and applied to the sensor or the vicinity of the sensor or sprayed. In addition, application and spraying can be performed by mixing fine particles having a particle diameter of 200 nm or less with those to be applied, so that the moisture-proof effect can be enhanced.

  In the case of contact with human skin, washing is often required. In that case, it may be required to withstand bending or contact with other things. In this case, depending on the physical properties of the material, it is preferable to apply a paint or the like containing fine particles, particularly ultrafine particles, to the surface of the sensor body by coating or the like. Further, as an example of the moisture proof measure, a conventional moisture proof technique can be used.

  FIG. 10 is a schematic view of a sensor device using a sensor having the structure shown in FIG. 9 at least partially as an embodiment of the present invention. Reference numeral 260e denotes a sensor holder of the sensor device, and 262a to 262f denote sensor main bodies arranged substantially in parallel with each other. The sensor main body is arranged in a direction substantially orthogonal to the sensors 261a to 261d arranged in substantially parallel with each other. It constitutes the sensor body. By configuring each sensor body with one sensor, the cost of the sensor device can be reduced. Hereinafter, the same is applied, but the alphabets following the numerals such as a, d, f, and v mean arbitrary numerals that are increased or decreased according to the actual situation or as necessary.

  Although not shown, at least one of the sensor main bodies 261a to 261d and 262a to 262f is provided with a sub-sensor that forms a predetermined angle with the sensor main body to provide pressure detection reliability. Can be increased.

  More preferably, as many auxiliary sensors as possible are provided with sensors wound around each of the sensor main bodies 261a to 261d and / or the sensor main bodies 262a to 262f as sub-sensors to further increase detection reliability. Can be enhanced.

  Further, a sensor different from the sensor at an angle of several degrees or less may be arranged as an auxiliary sensor in each sensor main body, for example, to improve detection reliability.

  Further, each sensor main body is formed to be thinner, and the narrowly formed sub-sensor is wound around each of the main bodies, so that usability can be improved, sensor detection reliability can be improved, and sensitivity can be increased.

  Further, in addition to each sensor main body, the sensor device of the present invention can be configured together with each sensor main body by weaving ordinary fibers that cannot detect pressure and displacement as described above. In addition, the ordinary fibers can be woven between the sensor main bodies 261a to 261v and / or the sensor main bodies 262a to 262f or at predetermined intervals to constitute the sensor device of the present invention. Further, the intervals between the sensor bodies 261a to 261d and the intervals between the sensor bodies 262a to 262f may be different. Further, at least a part of one of the sensor main bodies 261a to 261d and the sensor main bodies 262a to 262f can be replaced with the normal fiber instead of the sensor main body.

  For example, the sensor holding body 260e in FIG. 10 can use the mutual holding force generated by knitting each sensor main body as shown in the figure. Configuration is possible. For example, it is more preferable to arrange a nonwoven fabric in close contact with the sensor on at least one of the drawing side and the back side of FIG. By doing so, the strength of the sensor device can be increased without making the sensor body thinner or losing the flexibility of the sensor.

  When the health state of the living body to be measured is determined with reference to each characteristic point described later of the apical pulsation waveform, the horizontal axis of the apical pulsation waveform, that is, the time axis, is corrected as follows. . When the heart rate per minute of the living body to be measured is V, the heart rate correction coefficient is the square root of V / 60 (hereinafter, the square root of V / 60 is also referred to as √V / 60), and the time axis of the apical pulsation waveform Is corrected as described below and used as an apex pulsation diagram. That is, particularly preferably, when a trace of a 2A sound which is an aortic closing sound of a heart sound diagram can be found in a heart beat diagram, such as a notch which may appear delicately in the heart beat diagram waveform, at least the following features A value obtained by multiplying the actual time axis from the point P (2) to the position where the trace of the 2A sound of the heart sound chart is found in the apical pulsatile waveform by the heartbeat correction coefficient is used as the time axis. If no trace of the 2A sound is found in the apex pulsation waveform, a value obtained by multiplying the actual time axis from at least the following characteristic point P (2) to the position of the following characteristic point P (6) by the heartbeat correction coefficient. Is used as a time axis.

  FIG. 11 is a schematic diagram of a cross section near the sensor device when the sensor device of the present invention is applied as a pulsation detection sensor to the chest of a living body to be measured as an embodiment of the present invention. In the figure, only the minimum necessary for description is left, and the others are omitted. Reference numeral 266 denotes subcutaneous tissue of the thoracic epidermis, 267a to 267d denote ribs, and F denotes an arrow indicating a force applied to the sensor device from inside and / or outside the sensor device. The arrow is conceptually illustrated, and the direction of the force may not coincide with the direction of the arrow. In FIG. 11, the arrow F is described on the outer coating 260a that hits the outside of the sensor device. However, the technical idea of the present invention is not narrowly limited to this, and the arrow F is formed from outside the sensor device and / or from inside the sensor device. What is exerted or an internally generated force may be used.

  FIGS. 12 to 14 show examples of apical pulsation diagrams of the measured living body measured by contacting the sensor device shown in FIG. 11 with the chest epidermis of the measured living body. FIG. 12 is an apical pulsation diagram of a healthy person, and FIGS. 13 and 14 are apical pulsation diagrams of an unhealthy person, that is, a sick person. is there. 12 to 14, the vertical axis represents the detected intensity of the apical pulsation of the sensor body normalized to the minimum value of one beat of 0 and the maximum value to 1000, and the horizontal axis represents at least a partial correction. It is a time axis representing the apical pulsation diagram with respect to the time axis of the apical pulsation chart.

  12 to 14, reference numerals 185 and 195 denote an electrocardiogram, 185a and 195a denote R waves of a QRF wave of an electrocardiogram, 186 and 196 denote heart sound diagrams, 186b and 196b denote 2A sounds of a heart sound diagram, and 187 and 197 denote heart beats. FIG. 188 is a first derivative waveform of an apex pulsation diagram, P (1) to P (8) are characteristic points of an apex pulsation diagram described later, and a, e, and f are first derivative waveforms of an apex pulsation diagram described later. It is a feature point.

  The present inventor measures the apical pulsation diagram in the same manner as in the examples of FIGS. 12 to 14 for many of the living subjects to be measured this time, and includes the apical pulsation diagram determined by the conventional determination method, This was compared with the conventional diagnosis without using the apical rhythm chart of the health status. As a result, the present inventor has found a more accurate health state determination method than the health state determination method of the living body to be measured based on the apical pulsation diagram measured in the past.

  The measurement method of the apical pulsation diagram of the living body to be measured was measured by the following method. Unless otherwise specified, the sensor for measuring the apical pulsatility is located near the apex of the subject with the heart in the normal position in the left lateral position when the subject is in the normal position, and in the right lateral position when the subject is the right thoracic heart. , And synchronized with the R wave of the electrocardiogram QRS waveform, the electrocardiogram, the phonocardiogram and the apical pulsation chart were measured. The vertical and horizontal axes of the apex pulsatile waveform were taken in the same manner as in FIGS.

  As described later, the present inventor has also tried a method of applying the present invention to a method that can more easily determine and determine the health state of a living body to be measured, and has found a method that is useful for maintaining health and performing early consultation.

  Hereinafter, the characteristic points and the like of the apex pulsation diagram will be described. In the present invention, the apex pulsatile waveform for one beat of the living body to be measured is referred to as a unit waveform. From the predetermined time before the position on the apex pulsation waveform corresponding to each QRS-positive peak value of the electrocardiogram of the same measured body at the same time, that is, the R-wave (hereinafter also referred to as the QRS peak position), the next QRS peak An apex pulsatile waveform up to the predetermined time before the position is a unit waveform. The feature points P (1) to P (8) illustrated in the apical pulsation diagrams 187 and 197 are defined as follows.

  The characteristic point P (2) is defined as the lowest point C1 on the apex pulsation waveform at the QRS peak position ± 30 ms (millisecond) in the unit waveform. If C1 is unclear, the QRS peak position of the apex pulsation waveform is set as the feature point P (2).

  The feature point P (1) is defined as a positive vertex on the apex pulsatile waveform which is temporally within 160 ms before the QRS peak position. If a positive vertex on the apex pulsatile waveform cannot be found within 160 ms before the QRS peak position, the QRS peak position of the apex pulsatile waveform is set as the feature point P (1). In the latter case, the feature point P (1) is located at the same position as the feature point P (2).

  The feature point P (3) is defined as the positive vertex of the apex pulsatile waveform that is temporally 50 to 150 ms after the feature point P (2).

  The feature point P (5) is defined as a positive vertex closest to the position corresponding to the 2A sound of the apex pulsatile waveform between the 2A sound which is the aortic closing sound of the heart sound chart and less than 60 ms before it. If the feature point P (5) is temporally less than 40 ms before the position corresponding to the 2A sound on the apex pulsatile waveform, the feature point P (5) is changed to the feature point P (5). If it is set to '(5) and it is temporally before 40 ms to less than 50 ms from the position corresponding to the 2A sound in the apex pulsatile waveform, the feature point P (5) is changed to the feature point P' '(5 ), And when the point is temporally less than 50 ms to less than 60 ms from the position corresponding to the 2A sound in the apex pulsation waveform, the feature point P (5) is regarded as a feature point P ′ ″ (5). I do. Further, each feature point P ′ (5) is required unless it is necessary to express the deviation of each of the feature points P ′ (5), P ″ (5), and P ′ ″ (5) in a distinctive manner. , P ″ (5), or P ′ ″ (5), or when expressed collectively, is simply referred to as a feature point P (5).

  When the characteristic point P (4) does not exist on the apex pulsation waveform and the characteristic point P (5) as a generic term does not exist, the characteristic point P (2) From the apex pulsatile waveform that is 150 ms or more temporally from the time and 60 ms or more temporally before the 2A sound.

  The feature point P (6) is defined as the negative extreme value of the apex pulsatile waveform that is temporally 50 to 150 ms after the 2A sound.

  The feature point P (7) is temporally from the 2A sound to 100 to 240 ms later, and when the feature point P (6) exists, the apex located after the feature point P (6) The positive extreme value of the pulsatile waveform.

  The feature point P (8) is set as a positive extreme value of the apex pulsation waveform waveform temporally between the feature point P (7) and the feature point P (1) of the next unit waveform.

  The feature points P (1), P (2), P (3), P (4), P (5), P ′ (5), P ″ (5), P ′ ″ (5), P (6), P (7), and P (8) are defined as a first feature point group.

  The characteristic point P (1) of the apex pulsation diagram is defined as a positive vertex, and the waveform portion rising on the apex pulsation diagram from the front is defined as A wave, and the A wave in the first derivative waveform of the apex pulsation diagram is defined. Is defined as point a. The waveform portion rising from P (2) and having a positive extreme value is defined as an E wave, and the position of the positive peak value of the E wave in the primary differential waveform of the apex pulsation diagram is defined as a point e. The ascending wave portion rising from P (6) is defined as F wave, and the position of the positive peak value of the F wave in the first derivative waveform of the apex pulsation diagram is defined as point f. The height of each of the points a, e, and f, that is, the height of the vertical axis is defined as a, e, and f, respectively.

  The health care apparatus of the present invention requires a sensor for detecting a heartbeat, and detects an apical heartbeat of a living body to be measured, such as associated electronic circuits, data processing means, data storage means, display means, and transmission / reception means. It includes a means and a part having minimum functions necessary for processing the detected data to determine the health condition of the living body to be measured. However, the form is not narrowly limited to having a portion having a necessary minimum function, and various forms are possible according to the application.

  For example, the health management device of the present invention is not narrowly limited to those in which the above functions are mounted on the living body to be measured, and is not attached to the living body to be measured and the living body to be measured, but is arranged outside the living body to be measured It is also possible to configure the parts separately. For example, it has a sensor part having at least a receiving means, and the sensor part can be controlled from outside the living body to be measured to measure at least a part of the apical pulsation, and the measurement data can be sent outside the living body to be measured. A portable health management device according to the present invention includes a device that can be processed by the disposed health management device to determine the health state of the living body to be measured.

  Further, the feature points P (1) to P (8), A wave, E wave, F wave, a point, e point, f point, a, e, f, etc. Some of them do not appear in the first-order differential waveform, and some appear and some do not, depending on the health condition of the living body to be measured.

  The first feature point determination means is defined as a determination means for determining the presence or absence of at least two feature points in the first feature point group.

  The second feature point determination means performs P (1), P (2), and P (P) when the minimum vertical coordinate of the vertical axis of the unit waveform is 0 point and the maximum vertical coordinate of the vertical axis is 1000 points. (7) is defined as a judging means for judging the height of at least one of them.

  The third feature point determination means calculates the time between P (2) -P (3) between the feature points, that is, the time from P (2) to P (3) (hereinafter the same), P (6) -P (7) time, 2-P (6) time, that is, the time from 2A to P (6) (the same applies hereinafter), 2-P (7) time, P (3) -P (5) It is defined as a determination unit that determines a ratio of at least one of the time and the P (2) -P (6) time as a feature index.

  The first waveform judging means is compared with a waveform judging pattern built in the health management device of the present invention or an apex rhythm chart inputted from outside the health management device to the health management device of the present invention, and a part of the unit waveform is compared. It is defined as a determination means for determining the type of the target waveform or the entire waveform.

  The second waveform determining means is defined as determining means for determining the values of a, e, and f.

  The third waveform judging means determines that the apex pulsatile waveform changes in the vicinity of the point where the differential value between the point e and the lowest point immediately before the point f of the primary differential waveform is close to zero, and the differential waveform changes substantially horizontally as the tendency. Then, it is defined as a judging means for judging the presence or absence of a section which can be judged.

  The fourth waveform determining means determines that the position of the lowest point immediately before the point f of the first derivative waveform of the apex pulsatile waveform is the point where the differential value immediately before the lowest point is zero and the point immediately after the lowest point Is defined as a judging means for judging whether or not the differential value of is located in the first half between the zero point.

  The fifth waveform determining means determines whether or not the measured apical pulsation chart is a unimodal graph having P (3) and no P (5). In the case of the unimodal graph, P (3) is determined. The width of the graph at 700 points when the height of 3) is normalized to 1000 points is P (3), which is defined as the shoulder width after P (3). It is defined as a judgment means.

The sixth waveform determination means extracts a feature of the primary differential waveform between the 2A sound in the primary differential waveform of apex cardiogram waveform from a phase equivalent to a time in the vicinity of P (6), measured from its characteristics It is defined as determination means for determining the health state of a living body.

  The determining means in the health management device of the present invention determines the health state of the living body to be measured using the data processing result of the data processing means, and determines the first to third feature point determining means and the first to third characteristic points. It has at least one of the nine determination means of the sixth waveform determination means.

The positive extreme value of the A wave, which is a positive wave due to left atrial contraction, is defined as point A, and the health management device of the present invention determines whether the height of point A is less than 300 points or more than 300 points. When,
Determining means for determining whether the height of the C1 point is less than 300 points or more than 300 points;
determining means for determining whether the height of the point a is less than one-fourth, one-fourth or more, and less than one-half or one-half or more of the point e; ,
Determining means for determining whether the height of the point F is less than 50 points, 50 points or more, and less than 200 points, or 200 points or more;
determining means for determining whether the height of the point f is less than one half, one half or more, and less than two thirds or two thirds or more of the point e; ,
At P (7), at least one of the judging means for judging whether or not there is an overshoot, which is a phenomenon in which the rising wave reaches the peak, immediately thereafter falls temporarily and then rises again afterwards. It has one determining means.

  Furthermore, the health management device of the present invention may include a display unit and / or measurement data capable of displaying at least one of the evaluation result of the evaluation unit and the information on the waveform and the waveform type of the apexcardiogram, and the data of the data processing unit. , And data output means for outputting at least one of the evaluation result of the evaluation means and the evaluation result of the health condition of the living body to be measured.

  The inventor performed an apex pulsigram of more than 8000 subjects. The results were carefully compared with the results of the health assessment by the conventional method, which had been diagnosed without using an apical pulsation diagram. As a result, it has been concluded that the health condition of the subject can be determined even more accurately using the apical rhythm chart of the present invention. Then, the inventors have concluded that the determination method using the apex rhythm diagram of the present invention can alert the subject even if he is not a medical professional.

  The heart rate of the subject varies depending on the subject. In order to accurately determine the state of health, it is preferable to normalize the time of one beat, which is the sum of the systole and the diastole of the apical pulsation diagram. However, the movement of the heart is significantly different between systole and diastole. Therefore, the variation of the feature points differs depending on the type of the disease. Therefore, the present inventor considers the types of diseases and heart movements of healthy persons and sick persons, and by changing the normalization of the time axis of the apical pulsation diagram, it is possible to determine the health state more accurately. I found it.

  Therefore, according to the present invention, when a trace of the 2A sound can be found, such as a notch, the time obtained by multiplying the time axis from the feature point P (2) of the apical pulsation diagram to the 2A sound of the heart sound diagram by the heartbeat correction coefficient is obtained. When the axis is applied and no trace of the 2A sound is found, the time axis obtained by multiplying the time from the feature points P (2) to P (6) by the heartbeat correction coefficient is applied, whereby the subject is measured. They found that their health status could be determined more accurately.

  FIGS. 21, 22, and 23 are diagrams illustrating examples of notches. FIG. 21 shows that there is no feature point P (5), there is no P (4), there is a feature point P (3), and it is determined that the subject is a healthy person whose P3 half width is 100 ms or less. FIG. FIG. 22 is a diagram of an apex pulsation in which feature points P (3) and P (5) are present but P (4) is absent and is determined to be a healthy person, although feature points are not shown. FIG. 23 is a diagram showing an apex pulsation in which feature points P (3) and P (5) do not exist, and the fourth waveform determination means determines that the subject is sick, although feature points are not shown. That is, in the fourth waveform determining means, the position of the lowest point immediately before the point f of the first derivative waveform of the apex pulsatile waveform is determined by the point where the differential value immediately before the lowest point is zero and the lowest point. If it is located in the first half between the point where the differential value immediately after is zero, it is determined to be healthy, and if it is located in the second half, it is determined to be sick.

  Reference numerals 3, 11 and 21 are electrocardiograms, 4, 12 and 22 are electrocardiograms, 5, 13 and 23 are apical pulsation diagrams, 14, 24 are first derivative waveforms of apical pulsation diagrams, and 6, 16, and 25 are electrocardiograms. , 17, 17, 26 are the two tones of the heart chart, 10A is the notch corresponding to one of the heart charts, 20A, 18, 27 are the notches corresponding to the two sounds of the heart chart, and 14b is the pulsation chart The lowest point of the first derivative waveform, 14a is the zero point of the differential value temporally before the lowest point 4b, 14c is the zero point of the differential value temporally after the lowest point 4b, and 14d is the zero point of the differential value. Line. Since it was confirmed that the lowest point 4b was temporally behind the intermediate point between the zero points 14a and 14c of the differential value on the line 14d where the differential value was 0, the measured fabric was a sick person. Has been determined. Since the notches in FIGS. 22 and 23 are difficult to understand in the drawings, the portions enclosed by squares including the notches 18 and 27 in FIGS. 23 and 22 are enlarged in the upper right part of the entire drawings. It is shown. In the enlarged view, the intersection between the two sounds 26 of the heart sound diagram 22 and the wavy line in FIG. 22 and the intersection of the two sounds 17 and the wavy line of the heart sound diagram 12 in the heart sound diagram 23 are 2A sounds.

  In FIG. 21, the notch 10A corresponding to the heart sound 1 and the notch 20A corresponding to the heart sound 2 in the heart sound diagram clearly appear in the apex pulsatile diagram to the extent that they can be understood without enlarging the diagram. In FIGS. 22 and 23, the notch has a small amplitude and cannot be seen unless it is enlarged, but is detected and confirmed by the hyperopic circuit.

  Using data-processed apical pulsation charts, we examined data of healthy subjects and patients with valvular diseases and hypertension, and investigated apical pulsation charts that can respond to standard symptoms and their distribution status. .

  In hypertension, P (1) increases on the apex pulsatile chart, and at the same time, a of the first differential waveform of the apex pulsation chart also becomes a high value. Also, the height from P (6) to P (7) decreases. In some cases, P (7) may not be recognized.

  Hypertensive heart disease results from a period of hypertensive state. In hypertensive heart disease, P (5) is not observed in addition to the characteristic points of hypertension, and the posterior half width may increase. Neither P (3) nor P (5) is recognized and P (4) may be present. This is caused by left ventricular hypertrophy or left ventricular contraction disorder.

  In the case of a patient with dilated cardiomyopathy, none of P (3) and P (5) is recognized because P (3) and P (5) are not recognized because the entire left ventricle shows a thinning of the myocardial wall thickness and a decrease in contractile force. Is often present. Further, at the time of acute exacerbation of heart failure, P (7) increases, and f may be larger than e in the first derivative waveform of the apex pulsation diagram.

  In the case of hypertrophic cardiomyopathy, P (5) may not be present due to local, distorted hypertrophy of the left ventricle. Further, when there is a remarkable hypertrophy, P (6) may not be recognized due to a decrease in diastolic function. In general, the contractility is maintained, but P (3) may not be observed due to the enlargement described above. Due to the decrease in dilatation, P (1) is often increased and, at the same time, a of the first derivative waveform of the apex pulsation diagram is often displayed.

The following can be said about valvular disease.
In the case of aortic regurgitation, since the blood flows backward from the aorta to the left ventricle, a curve that rises from P (6) to the right ascending to the start point of P (1) may be observed on the apex pulsation chart. . In the case of altitude backflow, the position of the starting point of P (1) may exceed 500 points. P (5) may not be recognized due to efferent left ventricular hypertrophy.
In the case of aortic stenosis, afferent left ventricular hypertrophy is observed, and P (1) increases due to diastolic dysfunction, and at the same time, a of the first differential waveform of the apex pulsation diagram also increases. Also, the height from P (6) to P (7) decreases. In some cases, P (7) may not be recognized. Due to aortic stenosis, left ventricular systolic time is prolonged, and P (3) may be absent and P (4) may occur.
In the case of mitral stenosis, the mitral orifice becomes narrow, so that P (6) to P (7) are small, and a gently rising waveform from P (7) to P (1) is exhibited. There are many. Due to the enhancement of the I sound, it often shows traces and notches that match the I sound.
In the case of mitral regurgitation, a large amount of blood flows into the left ventricle from the left atrium during diastole because blood flows back from the left ventricle to the left atrium during systole. Therefore, P (7) increases. F of the first derivative waveform of the apex pulsation diagram shows a high value. The left ventricle exhibits efferent hypertrophy, similar to aortic regurgitation. Therefore, P (5) may not exist.

  In the case of myocardial infarction disease, extensive myocardial damage occurs in the anterior wall and anterior septal infarction due to obstruction of the left anterior descending coronary artery. Both contractile and diastolic abilities are reduced. Therefore, neither P (3) nor P (5) is recognized, and P (4) may be present. In addition, even if P (3) exists, P (5) is often not recognized. In the acute phase, P (7) may be high. When heart failure resolves, P (7) often decreases.

  Other causes of myocardial damage (aorticitis syndrome, cardiac sarcoidosis, etc.) and secondary myocardial damage due to impaired stimulation (e.g., complete left leg block, intraventricular conduction impairment) can also result in systolic or diastolic impairment.

  The apical rhythm chart also shows various characteristic points according to each disease. For example, in myocardial damage due to the above and other causes, as the severity increases, neither P (3) nor P (5) is recognized, and P (4) often exists.

  In the case of a stimulus conduction system disorder, for example, in the case of a complete left leg block or intraventricular conduction disorder, the contraction time of the left ventricle becomes longer, so that P (3) does not exist and P (4) is indicated. There are many.

  FIG. 15 is a schematic diagram illustrating an example of a display device of the portable health management device of the present invention. Reference numeral 1000 denotes a display device, 1000a denotes a frame portion of the display device, 1000b denotes a display screen, and 1001 to 1009 denote display portions allocated to the display screen. The number and layout of the display portions 1001 to 1009, enlargement / reduction, movement, and the like of each display portion can be appropriately changed by software.

  In the display part, for example, when a commonly used display for a mobile phone or a smartphone can be used as appropriate, in addition to these, an apical pulsation diagram in which the health state of the living body to be measured is to be examined, An apical pulsation chart of a healthy person other than the living body to be examined, an average apical pulsation chart or numerical value for evaluating the presence or absence of a disease in a sick person, an apical pulsation chart or numerical value used as a boundary between a sick person and a healthy person, statistics Information necessary for knowing the health condition stored in a memory (not shown), such as an apical pulsation diagram or a numerical value in consideration of the value, can be displayed as appropriate.

  These memories and display functions may be comprehensively provided in the portable health management device of the present invention, or may be provided only with frequently used ones. In addition, the portable health management device of the present invention may be a device that displays the health state of the living body to be measured, which is determined from the measured apical beats, using colors, numerical values, codes, or the like, instead of a graph or the like. For example, the judgment that the health condition is extremely high is determined by blue or predetermined characters or numerical values indicating that the health condition is extremely high, and the judgment that the health condition is not extremely high but the possibility of the health condition is high is high. The judgment that the possibility of a diseased person such as hypertension, valvular disease, myocardial infarction, etc. is extremely high with green or predetermined characters or numerical values indicating the state is red or predetermined characters or numerical values indicating the disease state The device represented by

  In the portable health management device of the present invention, the display function for a mobile phone or a smartphone is an example and is not essential. As described above, various variations are possible, such as a high-function product, a user-friendly device, for example, a small device, a simplified or single-function device, and an inexpensive product.

  Although not shown, an adjustment device for the time axis of the apical pulsation diagram is arranged in the health management device. In this mode, as is often used in smartphones, enlargement / reduction may be performed with a finger, or enlargement / reduction means such as a knob may be used.

  In the portable health management device of the present invention, the time of the characteristic point P (2) and the time on the cardiac pulsation diagram corresponding to the next 2A sound, and the characteristic point P (2) The time between and the next feature point P (6) is important. It is preferable to arrange means for easily detecting, correcting, or adjusting these time intervals. Further, the electrocardiogram, the electrocardiogram, and the differential waveform chart are the same as described above.

  In addition, time is determined so that the measured feature points P (2) and P (6) of the apex pulsogram and the feature points P (2) and P (6) of the other apex pulsograms match. The axes can be modified and compared.

  In the portable health management device of the present invention, by arranging the adjustment means on the vertical axis, it is possible to easily determine a feature point.

  In the display part of FIG. 15, at least one of the apical pulsation diagram and the health state data of the measured living body is displayed to facilitate the transition of the determination of the health state, and the measured living body is easily consulted with a medical institution. be able to.

  16 and 17 are diagrams illustrating an example in which the health state of the living body to be measured is determined using, for example, the display device of FIG. Reference symbol A is a measured apical pulsation diagram of the measured living body, B is an average apical pulsation diagram of the living body determined to be a healthy person used for comparison, and P (1) to P (7) are the measured measured pulsation diagrams. The characteristic points P (1) S to P (7) S of the apical pulsation diagram of the living body are the respective characteristic points of the average apical pulsation diagram being analyzed. FIG. 16A shows the apex pulsation diagram of the measured living body displayed on the display portion 1001 of FIG. 15, and FIG. 16B shows the average apex pulsation diagram displayed on the display portion 1002 of FIG. FIG. 10 is a diagram that is copied and displayed next to A in a display portion 1001. As can be seen from the figure, feature points P (1) to P (3) and P (5) to P (7) exist in the apical pulsation diagram A, but P (4) does not. Similarly, feature points P (1) S to P (3) S and P (5) S to P (7) S exist in the apex pulsation diagram B, but P (4) S does not exist.

  FIG. 17 is a diagram in which the apex pulsation diagram B in FIG. For convenience of explanation, the apical pulsation diagrams A and B, which are superimposed, are slightly shifted above and below the figures. In FIG. 16, only the feature points P (1) to P (7) and the feature points and P (1) S to P (7) S are shown in FIG. 16 for convenience of size, but in FIG. is there.

  In FIG. 17, the characteristic point P (1) which is the positive extreme value of the A wave when the detected value of the apex pulsation, that is, the value on the vertical axis is normalized with the minimum value of one heartbeat normalized to 0 and the maximum value to 1000. ) The detection intensity does not exceed 300, and the blood pressure of the measured living body is normal blood pressure, and the characteristic points P (2), P (3), P (6), and P (7) are in the normal range, and P (5). Is P ′ (5). P (2) -P (3) time between feature points, that is, time from P (2) to P (3) (the same applies hereinafter), P (6) -P (7) time, 2-P (6) time, that is, time from 2A sound to P (6) (the same applies hereinafter), 2-P (7) time, P (3) -P (5) time and P (2) -P (6 ) Time ratio is also normal. In addition, as a result of the judgment by each judging means, all are within the normal range.

  It can be said that the subject to be measured in the apical pulsation diagram shown in FIG. 17 is extremely likely to be a healthy person. In this sense, the health state of the living body to be measured is represented by a blue mark indicating that the possibility of being a healthy person is extremely high.

18 and 19 are apical pulsation diagrams of a living body to be measured which are different from the living body to be measured in FIGS. 16 and 17, wherein reference symbol C denotes a measured apical pulsation diagram of the living body to be measured, and D denotes a patient used for comparison. P (1) to P (7) are the average apical pulsation diagrams of the living body determined as, and P (1) S to P (7) are the characteristic points of the measured apical pulsation chart of the measured living body. S is each feature point of the average apex rhythm of the patient being analyzed. FIG. 18C is an apical pulsation diagram of the measured living body displayed on the display portion 1001 of FIG. 15, and FIG. 18D is an average apical heartbeat of the sick person displayed on the display portion 1003 of FIG. FIG. 14 is a diagram in which a moving image is copied and displayed next to C in a display portion 1001. As can be seen from the figure, although the feature points P (1), (2), P (4), P (6), and P (7) exist in the apex pulsation diagram C, P (3) P ( 5) does not exist. Similarly, there are feature points P (1) S, (2) S, P (4) S, P (6) S, and P (7) S in the average apical rhythm chart D of the patient. , P (3) S and P (5) S do not exist. This living body to be measured was found to have dilated cardiomyopathy.

  It can be said that the living body to be measured in the apical pulsation diagram shown in FIG. 19 is very likely to be a patient. In this sense, the health condition of the living body to be measured is represented by a red mark indicating that the possibility of being a sick person is extremely high.

  The inventor has reached the above conclusion as a result of comparing the results of measurement of the apex pulsation of more than 8,000 persons to be measured with the results obtained by using a method not using the conventional results of measurement of the apex pulsation. It is.

  The above-mentioned usage does not require a medical institution to perform an expensive test or perform an operation. In today's information processing technology and management system, the judgment method of each feature point can be created so that the result can be obtained by the information processing technology. It is not very difficult. As described above, the portable health management device or the health management method of the present invention is used for daily health management, and the health of the subject is managed on a daily basis. This greatly contributes to a significant reduction in medical expenses, and also brings a great advantage that medical expenses can be concentrated on treatment of a disease that one really wants to treat.

  The portable health management device and the health management method of the present invention include, for example, as described above, a sensor unit for detecting the movement of the apex and a small attached part attached to the chest of a living body, and controlling it from outside the body. In addition, the above-mentioned processing can be performed by the measuring instrument body outside the living body. It has also begun to be reported that, during the rapid development of healthcare, a heart disease that was previously thought to be of little relevance is closely linked to another disease.

  Heart disease detection is not limited to apex. For example, measurement of one beat of the jugular vein and the carotid artery includes a lot of information. As a simple measurement method, there is a method in which a foil-like detection body is attached to a part of the neck as a sensor to detect the movement. There is also a method of detecting the reflection of the wave by applying a cosmetic containing a material that easily reflects the wave such as visible light or infrared light to the neck.

  The present inventor compared the apex pulsation diagrams and health states of many measured organisms and found that the health state of the measured organisms was determined more accurately. For example, when P (3) and P ′ (5) are present, the possibility of left ventricular contraction disorder is extremely low, and when P (3) and P ″ (5) are present, the possibility of left ventricular contraction disorder is extremely low. If it is low and there are P (3) and P ′ ″ (5), the display method is devised so as to recommend a diagnosis by a doctor worried about the possibility of left ventricular contraction disorder. In the case of a unimodal waveform, if the post-P3 half width is 100 ms or more, it may be considered that there is a possibility of left ventricular contraction disorder or left ventricular hypertrophy.

  As a simple method for determining the apex pulsation diagram, the time axis is corrected so that the characteristic points P (2) and P (6) of the living body to be determined match, and the various determination means are applied. is there.

  FIG. 20 shows an apparatus which measures the apical pulsation wrapped around the chest to determine the health condition of the living body to be measured. Reference numeral 100 is a belt-type portable health management device, 101 is a sensor device, 102 is a power supply unit, 103 is a transmission / reception unit, 104 is a display unit, 105 and 106 are adjustment tools, 107 and 108 are mounting units, and 109 is a sensor holding unit. It is a belt. The paper surface in FIG. 20 is the surface to be attached to the chest of the living body to be measured, and the sensor body is arranged on the surface to be attached to the chest. The display unit 104 has a main body disposed on the back side of the drawing. The sensor holding belt 109 is made of a stretchable cloth or leather, or other material that can be wrapped around the chest of the living body so that the sensor device 101 can be pressed against the skin of the living body to be measured. The mounting portions 107 and 108 are made of fasteners such as hook-and-loop fasteners and hooks. The sensor holding belt 109 is pulled to both sides in the longitudinal direction, and the mounting portions 107 and 108 are overlapped in a stretched state to measure the sensor device 101. The mounting part is stopped while being pressed against the skin of the living body. If the apex pulsation diagram is not correctly detected by looking at the display unit 104 after being attached to the chest, the adjusters 105 and 106, which are also arranged on the back side of the sensor device 101 of the sensor holding belt 109, are correctly adjusted. To be displayed.

  The present invention is extremely important in the medical treatment of the circulatory system, and a pulsatile chart on the chest and abdomen that was not accurately measured and recorded without having a very high level of specialized knowledge, can be easily performed by non-medical professionals Since it can be measured and determined in a wide range, it can be used for wearable devices, sports, and the like, and can be used in a wide range of fields such as general healthcare equipment, sports equipment, and medical supplies. .

Claims (5)

Sensors and / or sensor and / or an electric field and at least one of the living body using a detection sensor constructed using a sensor for detecting a change apical beat of the magnetic field detecting a change in the reflection state of the wave detecting pressure changes in the figure, test detection value axis and the vertical axis the apex cardiogram, when expressed on the horizontal axis in orthogonal coordinate axes and the time axis, only by multiplying the correction coefficient during the systole of the time axis, the health care device comprising a Turkey to determine the health state of the measurement living body. Sensors and / or sensor and / or an electric field and at least one of the living body using a detection sensor constructed using a sensor for detecting a change apical beat of the magnetic field detecting a change in the reflection state of the wave detecting pressure changes in the figure, test detection value axis and the vertical axis the apex cardiogram, when expressed on the horizontal axis in orthogonal coordinate axes and the time axis, the feature point P (2) correction only the time axis between to P (6) multiplied by a coefficient, health care device comprising a Turkey to determine the health status of the subject living body.   3. The health management device according to claim 1, wherein a correction coefficient by which a time axis when a heart rate of the living body to be measured is V is ΔV / 60, which means a square root of V / 60. 4. And health management equipment. Sensors and / or sensor and / or an electric field and at least one of the living body using a detection sensor constructed using a sensor for detecting a change apical beat of the magnetic field detecting a change in the reflection state of the wave detecting pressure changes in the figure, test detection value axis and the vertical axis the apex cardiogram, when expressed on the horizontal axis in orthogonal coordinate axes and the time axis, apical cardiogram be a reference determined determining apex cardiogram health feature point P (2) to each other and the feature point P (6) so as to coincide with each other time to correct the axis of the health management device comprising the Turkey to determine the health status of the subject living body.   The health care device according to any one of claims 1 to 4, wherein the detection sensor is a fibrous sensor.